Id |
Subject |
Object |
Predicate |
Lexical cue |
T454 |
0-11 |
NN |
denotes |
Suppression |
T455 |
12-14 |
IN |
denotes |
of |
T456 |
15-21 |
NNP |
denotes |
GATA-3 |
T457 |
22-29 |
NNP |
denotes |
Nuclear |
T458 |
30-36 |
NN |
denotes |
Import |
T459 |
37-40 |
CC |
denotes |
and |
T460 |
41-56 |
NNP |
denotes |
Phosphorylation |
T461 |
56-57 |
: |
denotes |
: |
T462 |
58-59 |
NNP |
denotes |
A |
T463 |
60-65 |
NNP |
denotes |
Novel |
T464 |
66-75 |
NNP |
denotes |
Mechanism |
T465 |
76-78 |
IN |
denotes |
of |
T466 |
79-93 |
NNP |
denotes |
Corticosteroid |
T467 |
94-100 |
NNP |
denotes |
Action |
T468 |
101-103 |
IN |
denotes |
in |
T469 |
104-112 |
NNP |
denotes |
Allergic |
T470 |
113-120 |
NNP |
denotes |
Disease |
T471 |
455-465 |
NNP |
denotes |
Background |
T472 |
466-472 |
NNP |
denotes |
GATA-3 |
T473 |
473-478 |
VBZ |
denotes |
plays |
T474 |
479-480 |
DT |
denotes |
a |
T475 |
481-489 |
JJ |
denotes |
critical |
T476 |
490-494 |
NN |
denotes |
role |
T477 |
495-497 |
IN |
denotes |
in |
T478 |
498-508 |
VBG |
denotes |
regulating |
T479 |
509-512 |
DT |
denotes |
the |
T480 |
513-523 |
NN |
denotes |
expression |
T481 |
524-526 |
IN |
denotes |
of |
T482 |
527-530 |
DT |
denotes |
the |
T483 |
531-540 |
NNS |
denotes |
cytokines |
T484 |
541-552 |
VBP |
denotes |
interleukin |
T485 |
553-554 |
-LRB- |
denotes |
( |
T486 |
554-556 |
NNP |
denotes |
IL |
T487 |
556-557 |
-RRB- |
denotes |
) |
T488 |
557-559 |
CD |
denotes |
-4 |
T489 |
559-560 |
, |
denotes |
, |
T490 |
561-565 |
NN |
denotes |
IL-5 |
T491 |
565-566 |
, |
denotes |
, |
T492 |
567-570 |
CC |
denotes |
and |
T493 |
571-576 |
NN |
denotes |
IL-13 |
T494 |
577-581 |
IN |
denotes |
from |
T495 |
582-583 |
NNP |
denotes |
T |
T496 |
584-592 |
JJ |
denotes |
helper-2 |
T497 |
593-594 |
-LRB- |
denotes |
( |
T498 |
594-597 |
JJ |
denotes |
Th2 |
T499 |
597-598 |
-RRB- |
denotes |
) |
T500 |
599-604 |
NNS |
denotes |
cells |
T501 |
605-608 |
CC |
denotes |
and |
T502 |
609-618 |
RB |
denotes |
therefore |
T503 |
619-621 |
VBZ |
denotes |
is |
T504 |
622-623 |
DT |
denotes |
a |
T505 |
624-627 |
JJ |
denotes |
key |
T506 |
628-636 |
NN |
denotes |
mediator |
T507 |
637-639 |
IN |
denotes |
of |
T508 |
640-648 |
JJ |
denotes |
allergic |
T509 |
649-657 |
NNS |
denotes |
diseases |
T510 |
657-658 |
. |
denotes |
. |
T511 |
659-674 |
NNS |
denotes |
Corticosteroids |
T512 |
675-678 |
VBP |
denotes |
are |
T513 |
679-685 |
RB |
denotes |
highly |
T514 |
686-695 |
JJ |
denotes |
effective |
T515 |
696-698 |
IN |
denotes |
in |
T516 |
699-710 |
VBG |
denotes |
suppressing |
T517 |
711-719 |
JJ |
denotes |
allergic |
T518 |
720-732 |
NN |
denotes |
inflammation |
T519 |
732-733 |
, |
denotes |
, |
T520 |
734-737 |
CC |
denotes |
but |
T521 |
738-743 |
PRP$ |
denotes |
their |
T522 |
744-751 |
NNS |
denotes |
effects |
T523 |
752-754 |
IN |
denotes |
on |
T524 |
755-761 |
NN |
denotes |
GATA-3 |
T525 |
762-765 |
VBP |
denotes |
are |
T526 |
766-773 |
JJ |
denotes |
unknown |
T527 |
773-774 |
. |
denotes |
. |
T528 |
775-777 |
PRP |
denotes |
We |
T529 |
778-790 |
VBD |
denotes |
investigated |
T530 |
791-794 |
DT |
denotes |
the |
T531 |
795-801 |
NN |
denotes |
effect |
T532 |
802-804 |
IN |
denotes |
of |
T533 |
805-808 |
DT |
denotes |
the |
T534 |
809-823 |
JJ |
denotes |
corticosteroid |
T535 |
824-835 |
NN |
denotes |
fluticasone |
T536 |
836-846 |
NN |
denotes |
propionate |
T537 |
847-849 |
IN |
denotes |
on |
T538 |
850-856 |
JJ |
denotes |
GATA-3 |
T539 |
857-867 |
NN |
denotes |
regulation |
T540 |
868-870 |
IN |
denotes |
in |
T541 |
871-876 |
JJ |
denotes |
human |
T542 |
877-890 |
NNS |
denotes |
T-lymphocytes |
T543 |
891-893 |
IN |
denotes |
in |
T544 |
894-899 |
NN |
denotes |
vitro |
T545 |
900-903 |
CC |
denotes |
and |
T546 |
904-906 |
IN |
denotes |
in |
T547 |
907-911 |
NN |
denotes |
vivo |
T548 |
911-912 |
. |
denotes |
. |
T549 |
914-921 |
NNS |
denotes |
Methods |
T550 |
922-925 |
CC |
denotes |
and |
T551 |
926-934 |
NNS |
denotes |
Findings |
T552 |
935-937 |
IN |
denotes |
In |
T553 |
938-939 |
DT |
denotes |
a |
T554 |
940-941 |
NNP |
denotes |
T |
T555 |
942-952 |
NN |
denotes |
lymphocyte |
T556 |
953-957 |
NN |
denotes |
cell |
T557 |
958-962 |
NN |
denotes |
line |
T558 |
963-964 |
-LRB- |
denotes |
( |
T559 |
964-970 |
JJ |
denotes |
HuT-78 |
T560 |
970-971 |
-RRB- |
denotes |
) |
T561 |
972-975 |
CC |
denotes |
and |
T562 |
976-986 |
JJ |
denotes |
peripheral |
T563 |
987-992 |
NN |
denotes |
blood |
T564 |
993-1004 |
NN |
denotes |
mononuclear |
T565 |
1005-1010 |
NNS |
denotes |
cells |
T566 |
1011-1021 |
VBN |
denotes |
stimulated |
T567 |
1022-1024 |
IN |
denotes |
by |
T568 |
1025-1033 |
JJ |
denotes |
anti-CD3 |
T569 |
1034-1037 |
CC |
denotes |
and |
T570 |
1038-1047 |
JJ |
denotes |
anti-CD28 |
T571 |
1048-1050 |
IN |
denotes |
in |
T572 |
1051-1056 |
NN |
denotes |
vitro |
T573 |
1057-1059 |
PRP |
denotes |
we |
T574 |
1060-1072 |
VBD |
denotes |
demonstrated |
T575 |
1073-1077 |
IN |
denotes |
that |
T576 |
1078-1089 |
NN |
denotes |
fluticasone |
T577 |
1090-1098 |
NNS |
denotes |
inhibits |
T578 |
1099-1106 |
JJ |
denotes |
nuclear |
T579 |
1107-1120 |
NN |
denotes |
translocation |
T580 |
1121-1123 |
IN |
denotes |
of |
T581 |
1124-1130 |
NNP |
denotes |
GATA-3 |
T582 |
1131-1134 |
CC |
denotes |
and |
T583 |
1135-1145 |
NN |
denotes |
expression |
T584 |
1146-1148 |
IN |
denotes |
of |
T585 |
1149-1152 |
JJ |
denotes |
Th2 |
T586 |
1153-1162 |
NNS |
denotes |
cytokines |
T587 |
1163-1166 |
IN |
denotes |
via |
T588 |
1167-1168 |
DT |
denotes |
a |
T589 |
1169-1178 |
NN |
denotes |
mechanism |
T590 |
1179-1190 |
JJ |
denotes |
independent |
T591 |
1191-1193 |
IN |
denotes |
of |
T592 |
1194-1201 |
JJ |
denotes |
nuclear |
T593 |
1202-1211 |
NN |
denotes |
factor-κB |
T594 |
1212-1215 |
CC |
denotes |
and |
T595 |
1216-1218 |
VBZ |
denotes |
is |
T596 |
1219-1222 |
JJ |
denotes |
due |
T597 |
1222-1223 |
, |
denotes |
, |
T598 |
1224-1226 |
IN |
denotes |
in |
T599 |
1227-1231 |
NN |
denotes |
part |
T600 |
1231-1232 |
, |
denotes |
, |
T601 |
1233-1235 |
TO |
denotes |
to |
T602 |
1236-1247 |
NN |
denotes |
competition |
T603 |
1248-1255 |
IN |
denotes |
between |
T604 |
1256-1262 |
NNP |
denotes |
GATA-3 |
T605 |
1263-1266 |
CC |
denotes |
and |
T606 |
1267-1270 |
DT |
denotes |
the |
T607 |
1271-1287 |
JJ |
denotes |
ligand-activated |
T608 |
1288-1302 |
NN |
denotes |
glucocorticoid |
T609 |
1303-1311 |
NN |
denotes |
receptor |
T610 |
1312-1315 |
IN |
denotes |
for |
T611 |
1316-1323 |
JJ |
denotes |
nuclear |
T612 |
1324-1333 |
NN |
denotes |
transport |
T613 |
1334-1341 |
IN |
denotes |
through |
T614 |
1342-1345 |
DT |
denotes |
the |
T615 |
1346-1353 |
JJ |
denotes |
nuclear |
T616 |
1354-1362 |
NN |
denotes |
importer |
T617 |
1363-1373 |
NN |
denotes |
importin-α |
T618 |
1373-1374 |
. |
denotes |
. |
T619 |
1375-1377 |
IN |
denotes |
In |
T620 |
1378-1386 |
NN |
denotes |
addition |
T621 |
1386-1387 |
, |
denotes |
, |
T622 |
1388-1399 |
NN |
denotes |
fluticasone |
T623 |
1400-1407 |
VBZ |
denotes |
induces |
T624 |
1408-1411 |
DT |
denotes |
the |
T625 |
1412-1422 |
NN |
denotes |
expression |
T626 |
1423-1425 |
IN |
denotes |
of |
T627 |
1426-1443 |
JJ |
denotes |
mitogen-activated |
T628 |
1444-1451 |
NN |
denotes |
protein |
T629 |
1452-1458 |
NN |
denotes |
kinase |
T630 |
1459-1460 |
-LRB- |
denotes |
( |
T631 |
1460-1464 |
NNP |
denotes |
MAPK |
T632 |
1464-1465 |
-RRB- |
denotes |
) |
T633 |
1466-1479 |
JJ |
denotes |
phosphatase-1 |
T634 |
1480-1481 |
-LRB- |
denotes |
( |
T635 |
1481-1486 |
NNP |
denotes |
MKP-1 |
T636 |
1486-1487 |
-RRB- |
denotes |
) |
T637 |
1487-1488 |
, |
denotes |
, |
T638 |
1489-1492 |
DT |
denotes |
the |
T639 |
1493-1503 |
JJ |
denotes |
endogenous |
T640 |
1504-1513 |
NN |
denotes |
inhibitor |
T641 |
1514-1516 |
IN |
denotes |
of |
T642 |
1517-1520 |
CD |
denotes |
p38 |
T643 |
1521-1525 |
NNP |
denotes |
MAPK |
T644 |
1525-1526 |
, |
denotes |
, |
T645 |
1527-1532 |
WDT |
denotes |
which |
T646 |
1533-1535 |
VBZ |
denotes |
is |
T647 |
1536-1545 |
JJ |
denotes |
necessary |
T648 |
1546-1549 |
IN |
denotes |
for |
T649 |
1550-1556 |
JJ |
denotes |
GATA-3 |
T650 |
1557-1564 |
JJ |
denotes |
nuclear |
T651 |
1565-1578 |
NN |
denotes |
translocation |
T652 |
1578-1579 |
. |
denotes |
. |
T653 |
1580-1585 |
DT |
denotes |
These |
T654 |
1586-1596 |
JJ |
denotes |
inhibitory |
T655 |
1597-1604 |
NNS |
denotes |
effects |
T656 |
1605-1607 |
IN |
denotes |
of |
T657 |
1608-1619 |
NN |
denotes |
fluticasone |
T658 |
1620-1623 |
VBP |
denotes |
are |
T659 |
1624-1629 |
JJ |
denotes |
rapid |
T660 |
1629-1630 |
, |
denotes |
, |
T661 |
1631-1637 |
JJ |
denotes |
potent |
T662 |
1637-1638 |
, |
denotes |
, |
T663 |
1639-1642 |
CC |
denotes |
and |
T664 |
1643-1652 |
VBN |
denotes |
prolonged |
T665 |
1652-1653 |
. |
denotes |
. |
T666 |
1654-1656 |
PRP |
denotes |
We |
T667 |
1657-1661 |
RB |
denotes |
also |
T668 |
1662-1674 |
VBD |
denotes |
demonstrated |
T669 |
1675-1679 |
IN |
denotes |
that |
T670 |
1680-1687 |
JJ |
denotes |
inhaled |
T671 |
1688-1699 |
NN |
denotes |
fluticasone |
T672 |
1700-1708 |
VBZ |
denotes |
inhibits |
T673 |
1709-1715 |
JJ |
denotes |
GATA-3 |
T674 |
1716-1723 |
JJ |
denotes |
nuclear |
T675 |
1724-1737 |
NN |
denotes |
translocation |
T676 |
1738-1740 |
IN |
denotes |
in |
T677 |
1741-1751 |
JJ |
denotes |
peripheral |
T678 |
1752-1757 |
NN |
denotes |
blood |
T679 |
1758-1769 |
NNS |
denotes |
lymphocytes |
T680 |
1770-1772 |
IN |
denotes |
of |
T681 |
1773-1781 |
NNS |
denotes |
patients |
T682 |
1782-1786 |
IN |
denotes |
with |
T683 |
1787-1793 |
NN |
denotes |
asthma |
T684 |
1794-1796 |
IN |
denotes |
in |
T685 |
1797-1801 |
NN |
denotes |
vivo |
T686 |
1801-1802 |
. |
denotes |
. |
T687 |
1804-1815 |
NNS |
denotes |
Conclusions |
T688 |
1816-1831 |
NNS |
denotes |
Corticosteroids |
T689 |
1832-1836 |
VBP |
denotes |
have |
T690 |
1837-1838 |
DT |
denotes |
a |
T691 |
1839-1845 |
JJ |
denotes |
potent |
T692 |
1846-1856 |
JJ |
denotes |
inhibitory |
T693 |
1857-1863 |
NN |
denotes |
effect |
T694 |
1864-1866 |
IN |
denotes |
on |
T695 |
1867-1873 |
JJ |
denotes |
GATA-3 |
T696 |
1874-1877 |
IN |
denotes |
via |
T697 |
1878-1881 |
CD |
denotes |
two |
T698 |
1882-1893 |
VBG |
denotes |
interacting |
T699 |
1894-1904 |
NNS |
denotes |
mechanisms |
T700 |
1905-1909 |
WDT |
denotes |
that |
T701 |
1910-1918 |
RB |
denotes |
potently |
T702 |
1919-1927 |
VBP |
denotes |
suppress |
T703 |
1928-1931 |
JJ |
denotes |
Th2 |
T704 |
1932-1940 |
NN |
denotes |
cytokine |
T705 |
1941-1951 |
NN |
denotes |
expression |
T706 |
1951-1952 |
. |
denotes |
. |
T707 |
1953-1957 |
DT |
denotes |
This |
T708 |
1958-1963 |
NN |
denotes |
novel |
T709 |
1964-1973 |
NN |
denotes |
mechanism |
T710 |
1974-1976 |
IN |
denotes |
of |
T711 |
1977-1983 |
NN |
denotes |
action |
T712 |
1984-1986 |
IN |
denotes |
of |
T713 |
1987-2002 |
NNS |
denotes |
corticosteroids |
T714 |
2003-2006 |
MD |
denotes |
may |
T715 |
2007-2014 |
VB |
denotes |
account |
T716 |
2015-2018 |
IN |
denotes |
for |
T717 |
2019-2022 |
DT |
denotes |
the |
T718 |
2023-2031 |
JJ |
denotes |
striking |
T719 |
2032-2040 |
JJ |
denotes |
clinical |
T720 |
2041-2049 |
NN |
denotes |
efficacy |
T721 |
2050-2052 |
IN |
denotes |
of |
T722 |
2053-2068 |
NNS |
denotes |
corticosteroids |
T723 |
2069-2071 |
IN |
denotes |
in |
T724 |
2072-2075 |
DT |
denotes |
the |
T725 |
2076-2085 |
NN |
denotes |
treatment |
T726 |
2086-2088 |
IN |
denotes |
of |
T727 |
2089-2097 |
JJ |
denotes |
allergic |
T728 |
2098-2106 |
NNS |
denotes |
diseases |
T729 |
2106-2107 |
. |
denotes |
. |
T730 |
2109-2115 |
VB |
denotes |
Please |
T731 |
2116-2119 |
VB |
denotes |
see |
T732 |
2120-2125 |
RB |
denotes |
later |
T733 |
2126-2128 |
IN |
denotes |
in |
T734 |
2129-2132 |
DT |
denotes |
the |
T735 |
2133-2140 |
NN |
denotes |
article |
T736 |
2141-2144 |
IN |
denotes |
for |
T737 |
2145-2152 |
NNS |
denotes |
Editors |
T738 |
2152-2153 |
POS |
denotes |
' |
T739 |
2154-2161 |
NN |
denotes |
Summary |
T2279 |
7246-7258 |
NNP |
denotes |
Inflammation |
T2280 |
7259-7261 |
IN |
denotes |
in |
T2281 |
7262-7270 |
JJ |
denotes |
allergic |
T2282 |
7271-7279 |
NNS |
denotes |
diseases |
T2283 |
7280-7284 |
JJ |
denotes |
such |
T2284 |
7285-7287 |
IN |
denotes |
as |
T2285 |
7288-7294 |
NN |
denotes |
asthma |
T2286 |
7294-7295 |
, |
denotes |
, |
T2287 |
7296-7304 |
NN |
denotes |
rhinitis |
T2288 |
7304-7305 |
, |
denotes |
, |
T2289 |
7306-7309 |
CC |
denotes |
and |
T2290 |
7310-7316 |
JJ |
denotes |
atopic |
T2291 |
7317-7327 |
NN |
denotes |
dermatitis |
T2292 |
7328-7330 |
VBZ |
denotes |
is |
T2293 |
7331-7339 |
VBN |
denotes |
mediated |
T2294 |
7340-7343 |
IN |
denotes |
via |
T2295 |
7344-7354 |
NN |
denotes |
expression |
T2296 |
7355-7357 |
IN |
denotes |
of |
T2297 |
7358-7361 |
DT |
denotes |
the |
T2298 |
7362-7371 |
NNS |
denotes |
cytokines |
T2299 |
7372-7383 |
VBP |
denotes |
interleukin |
T2300 |
7384-7385 |
-LRB- |
denotes |
( |
T2301 |
7385-7387 |
NNP |
denotes |
IL |
T2302 |
7387-7388 |
-RRB- |
denotes |
) |
T2303 |
7388-7390 |
CD |
denotes |
-4 |
T2304 |
7390-7391 |
, |
denotes |
, |
T2305 |
7392-7396 |
NN |
denotes |
IL-5 |
T2306 |
7396-7397 |
, |
denotes |
, |
T2307 |
7398-7401 |
CC |
denotes |
and |
T2308 |
7402-7407 |
NN |
denotes |
IL-13 |
T2309 |
7408-7412 |
IN |
denotes |
from |
T2310 |
7413-7414 |
NNP |
denotes |
T |
T2311 |
7415-7423 |
JJ |
denotes |
helper-2 |
T2312 |
7424-7425 |
-LRB- |
denotes |
( |
T2313 |
7425-7428 |
JJ |
denotes |
Th2 |
T2314 |
7428-7429 |
-RRB- |
denotes |
) |
T2315 |
7430-7435 |
NNS |
denotes |
cells |
T2316 |
7435-7436 |
. |
denotes |
. |
T2317 |
7437-7441 |
NN |
denotes |
IL-4 |
T2318 |
7442-7445 |
CC |
denotes |
and |
T2319 |
7446-7451 |
JJ |
denotes |
IL-13 |
T2320 |
7452-7460 |
VB |
denotes |
regulate |
T2321 |
7461-7464 |
DT |
denotes |
the |
T2322 |
7465-7475 |
NN |
denotes |
expression |
T2323 |
7476-7478 |
IN |
denotes |
of |
T2324 |
7479-7482 |
NNP |
denotes |
IgE |
T2325 |
7483-7487 |
IN |
denotes |
from |
T2326 |
7488-7489 |
NNP |
denotes |
B |
T2327 |
7490-7501 |
NNS |
denotes |
lymphocytes |
T2328 |
7501-7502 |
, |
denotes |
, |
T2329 |
7503-7510 |
IN |
denotes |
whereas |
T2330 |
7511-7515 |
NNP |
denotes |
IL-5 |
T2331 |
7516-7521 |
VBZ |
denotes |
plays |
T2332 |
7522-7523 |
DT |
denotes |
a |
T2333 |
7524-7527 |
JJ |
denotes |
key |
T2334 |
7528-7532 |
NN |
denotes |
role |
T2335 |
7533-7535 |
IN |
denotes |
in |
T2336 |
7536-7548 |
JJ |
denotes |
eosinophilic |
T2337 |
7549-7561 |
NN |
denotes |
inflammation |
T2338 |
7562-7563 |
NNP |
denotes |
[ |
T2339 |
7563-7564 |
CD |
denotes |
1 |
T2340 |
7564-7565 |
NNP |
denotes |
] |
T2341 |
7565-7566 |
. |
denotes |
. |
T2342 |
7567-7570 |
CD |
denotes |
Th2 |
T2343 |
7571-7580 |
NNS |
denotes |
cytokines |
T2344 |
7581-7584 |
VBP |
denotes |
are |
T2345 |
7585-7594 |
VBN |
denotes |
regulated |
T2346 |
7595-7597 |
IN |
denotes |
by |
T2347 |
7598-7601 |
DT |
denotes |
the |
T2348 |
7602-7606 |
NN |
denotes |
zinc |
T2349 |
7607-7613 |
NN |
denotes |
finger |
T2350 |
7614-7627 |
NN |
denotes |
transcription |
T2351 |
7628-7634 |
NN |
denotes |
factor |
T2352 |
7635-7641 |
NNP |
denotes |
GATA-3 |
T2353 |
7641-7642 |
, |
denotes |
, |
T2354 |
7643-7648 |
WDT |
denotes |
which |
T2355 |
7649-7651 |
VBZ |
denotes |
is |
T2356 |
7652-7665 |
RB |
denotes |
predominantly |
T2357 |
7666-7675 |
VBN |
denotes |
expressed |
T2358 |
7676-7678 |
IN |
denotes |
in |
T2359 |
7679-7682 |
JJ |
denotes |
Th2 |
T2360 |
7683-7688 |
NNS |
denotes |
cells |
T2361 |
7689-7690 |
VBP |
denotes |
[ |
T2362 |
7690-7691 |
CD |
denotes |
2 |
T2363 |
7691-7692 |
NNP |
denotes |
] |
T2364 |
7692-7693 |
, |
denotes |
, |
T2365 |
7693-7694 |
NNP |
denotes |
[ |
T2366 |
7694-7695 |
CD |
denotes |
3 |
T2367 |
7695-7696 |
NNP |
denotes |
] |
T2368 |
7696-7697 |
. |
denotes |
. |
T2369 |
7698-7704 |
JJ |
denotes |
GATA-3 |
T2370 |
7705-7715 |
VBZ |
denotes |
determines |
T2371 |
7716-7719 |
NNP |
denotes |
Th2 |
T2372 |
7720-7724 |
NN |
denotes |
cell |
T2373 |
7725-7740 |
NN |
denotes |
differentiation |
T2374 |
7741-7744 |
CC |
denotes |
and |
T2375 |
7745-7756 |
RB |
denotes |
selectively |
T2376 |
7757-7766 |
VBZ |
denotes |
activates |
T2377 |
7767-7770 |
DT |
denotes |
the |
T2378 |
7771-7780 |
NNS |
denotes |
promoters |
T2379 |
7781-7783 |
IN |
denotes |
of |
T2380 |
7784-7788 |
NN |
denotes |
IL-4 |
T2381 |
7788-7789 |
, |
denotes |
, |
T2382 |
7790-7794 |
NN |
denotes |
IL-5 |
T2383 |
7794-7795 |
, |
denotes |
, |
T2384 |
7796-7799 |
CC |
denotes |
and |
T2385 |
7800-7805 |
NN |
denotes |
IL-13 |
T2386 |
7806-7813 |
IN |
denotes |
through |
T2387 |
7814-7823 |
NN |
denotes |
chromatin |
T2388 |
7824-7835 |
VBG |
denotes |
remodelling |
T2389 |
7836-7837 |
NNP |
denotes |
[ |
T2390 |
7837-7838 |
CD |
denotes |
4 |
T2391 |
7838-7839 |
NNP |
denotes |
] |
T2392 |
7840-7841 |
NN |
denotes |
[ |
T2393 |
7841-7842 |
CD |
denotes |
7 |
T2394 |
7842-7843 |
NNP |
denotes |
] |
T2395 |
7843-7844 |
. |
denotes |
. |
T2396 |
7845-7848 |
DT |
denotes |
The |
T2397 |
7849-7852 |
JJ |
denotes |
key |
T2398 |
7853-7857 |
NN |
denotes |
role |
T2399 |
7858-7860 |
IN |
denotes |
of |
T2400 |
7861-7867 |
NN |
denotes |
GATA-3 |
T2401 |
7868-7870 |
IN |
denotes |
in |
T2402 |
7871-7879 |
JJ |
denotes |
allergic |
T2403 |
7880-7886 |
NN |
denotes |
airway |
T2404 |
7887-7899 |
NN |
denotes |
inflammation |
T2405 |
7900-7903 |
VBZ |
denotes |
has |
T2406 |
7904-7908 |
VBN |
denotes |
been |
T2407 |
7909-7921 |
VBN |
denotes |
demonstrated |
T2408 |
7922-7924 |
IN |
denotes |
in |
T2409 |
7925-7929 |
NNS |
denotes |
mice |
T2410 |
7930-7932 |
IN |
denotes |
by |
T2411 |
7933-7936 |
DT |
denotes |
the |
T2412 |
7937-7944 |
VBN |
denotes |
reduced |
T2413 |
7945-7952 |
NN |
denotes |
release |
T2414 |
7953-7955 |
IN |
denotes |
of |
T2415 |
7956-7959 |
JJ |
denotes |
Th2 |
T2416 |
7960-7969 |
NNS |
denotes |
cytokines |
T2417 |
7970-7972 |
IN |
denotes |
in |
T2418 |
7973-7980 |
NNS |
denotes |
animals |
T2419 |
7981-7988 |
VBN |
denotes |
treated |
T2420 |
7989-7993 |
IN |
denotes |
with |
T2421 |
7994-8011 |
JJ |
denotes |
dominant-negative |
T2422 |
8012-8019 |
NNS |
denotes |
mutants |
T2423 |
8020-8022 |
IN |
denotes |
of |
T2424 |
8023-8029 |
NN |
denotes |
GATA-3 |
T2425 |
8030-8033 |
CC |
denotes |
and |
T2426 |
8034-8036 |
IN |
denotes |
by |
T2427 |
8037-8042 |
JJ |
denotes |
local |
T2428 |
8043-8054 |
NN |
denotes |
application |
T2429 |
8055-8057 |
IN |
denotes |
of |
T2430 |
8058-8067 |
JJ |
denotes |
antisense |
T2431 |
8068-8084 |
NNS |
denotes |
oligonucleotides |
T2432 |
8085-8087 |
TO |
denotes |
to |
T2433 |
8088-8094 |
NNP |
denotes |
GATA-3 |
T2434 |
8095-8096 |
NNP |
denotes |
[ |
T2435 |
8096-8097 |
CD |
denotes |
8 |
T2436 |
8097-8098 |
NNP |
denotes |
] |
T2437 |
8098-8099 |
, |
denotes |
, |
T2438 |
8099-8100 |
NNP |
denotes |
[ |
T2439 |
8100-8101 |
CD |
denotes |
9 |
T2440 |
8101-8102 |
NNP |
denotes |
] |
T2441 |
8102-8103 |
. |
denotes |
. |
T2442 |
8104-8115 |
RB |
denotes |
Furthermore |
T2443 |
8115-8116 |
, |
denotes |
, |
T2444 |
8117-8128 |
JJ |
denotes |
conditional |
T2445 |
8129-8138 |
NN |
denotes |
knock-out |
T2446 |
8139-8141 |
IN |
denotes |
of |
T2447 |
8142-8145 |
DT |
denotes |
the |
T2448 |
8146-8151 |
NNP |
denotes |
Gata3 |
T2449 |
8152-8156 |
NN |
denotes |
gene |
T2450 |
8157-8159 |
IN |
denotes |
in |
T2451 |
8160-8164 |
NNS |
denotes |
mice |
T2452 |
8165-8172 |
VBZ |
denotes |
reduces |
T2453 |
8173-8183 |
NN |
denotes |
expression |
T2454 |
8184-8186 |
IN |
denotes |
of |
T2455 |
8187-8190 |
JJ |
denotes |
Th2 |
T2456 |
8191-8200 |
NNS |
denotes |
cytokines |
T2457 |
8201-8203 |
IN |
denotes |
in |
T2458 |
8204-8209 |
NN |
denotes |
vitro |
T2459 |
8210-8213 |
CC |
denotes |
and |
T2460 |
8214-8216 |
IN |
denotes |
in |
T2461 |
8217-8221 |
NN |
denotes |
vivo |
T2462 |
8222-8223 |
NNP |
denotes |
[ |
T2463 |
8223-8225 |
CD |
denotes |
10 |
T2464 |
8225-8226 |
NNP |
denotes |
] |
T2465 |
8226-8227 |
, |
denotes |
, |
T2466 |
8228-8231 |
CC |
denotes |
and |
T2467 |
8232-8239 |
JJ |
denotes |
similar |
T2468 |
8240-8247 |
NNS |
denotes |
results |
T2469 |
8248-8252 |
VBP |
denotes |
have |
T2470 |
8253-8257 |
VBN |
denotes |
been |
T2471 |
8258-8266 |
VBN |
denotes |
reported |
T2472 |
8267-8269 |
IN |
denotes |
in |
T2473 |
8270-8278 |
JJ |
denotes |
isolated |
T2474 |
8279-8285 |
NN |
denotes |
murine |
T2475 |
8286-8289 |
NNP |
denotes |
CD4 |
T2476 |
8289-8290 |
NNP |
denotes |
+ |
T2477 |
8291-8302 |
VBZ |
denotes |
lymphocytes |
T2478 |
8303-8304 |
NNP |
denotes |
[ |
T2479 |
8304-8306 |
CD |
denotes |
11 |
T2480 |
8306-8307 |
NNP |
denotes |
] |
T2481 |
8307-8308 |
. |
denotes |
. |
T2482 |
8309-8316 |
RB |
denotes |
Finally |
T2483 |
8316-8317 |
, |
denotes |
, |
T2484 |
8318-8327 |
NN |
denotes |
knockdown |
T2485 |
8328-8330 |
IN |
denotes |
of |
T2486 |
8331-8337 |
JJ |
denotes |
GATA-3 |
T2487 |
8338-8348 |
NN |
denotes |
expression |
T2488 |
8349-8354 |
VBG |
denotes |
using |
T2489 |
8355-8360 |
NNP |
denotes |
siRNA |
T2490 |
8361-8363 |
IN |
denotes |
in |
T2491 |
8364-8369 |
JJ |
denotes |
human |
T2492 |
8370-8371 |
NNP |
denotes |
T |
T2493 |
8372-8377 |
NNS |
denotes |
cells |
T2494 |
8378-8385 |
NNS |
denotes |
results |
T2495 |
8386-8388 |
IN |
denotes |
in |
T2496 |
8389-8393 |
NN |
denotes |
loss |
T2497 |
8394-8396 |
IN |
denotes |
of |
T2498 |
8397-8405 |
JJ |
denotes |
anti-CD3 |
T2499 |
8405-8406 |
NN |
denotes |
/ |
T2500 |
8406-8419 |
JJ |
denotes |
CD28-mediated |
T2501 |
8420-8423 |
JJ |
denotes |
Th2 |
T2502 |
8424-8432 |
NN |
denotes |
cytokine |
T2503 |
8433-8443 |
NN |
denotes |
expression |
T2504 |
8444-8445 |
NNP |
denotes |
[ |
T2505 |
8445-8447 |
CD |
denotes |
12 |
T2506 |
8447-8448 |
NNP |
denotes |
] |
T2507 |
8448-8449 |
. |
denotes |
. |
T2508 |
8450-8452 |
IN |
denotes |
In |
T2509 |
8453-8458 |
NN |
denotes |
order |
T2510 |
8459-8462 |
IN |
denotes |
for |
T2511 |
8463-8469 |
NN |
denotes |
GATA-3 |
T2512 |
8470-8472 |
TO |
denotes |
to |
T2513 |
8473-8481 |
VB |
denotes |
regulate |
T2514 |
8482-8486 |
NN |
denotes |
gene |
T2515 |
8487-8497 |
NN |
denotes |
expression |
T2516 |
8497-8498 |
, |
denotes |
, |
T2517 |
8499-8501 |
PRP |
denotes |
it |
T2518 |
8502-8506 |
MD |
denotes |
must |
T2519 |
8507-8518 |
VB |
denotes |
translocate |
T2520 |
8519-8523 |
IN |
denotes |
from |
T2521 |
8524-8527 |
DT |
denotes |
the |
T2522 |
8528-8537 |
NN |
denotes |
cytoplasm |
T2523 |
8538-8542 |
IN |
denotes |
into |
T2524 |
8543-8546 |
DT |
denotes |
the |
T2525 |
8547-8554 |
NN |
denotes |
nucleus |
T2526 |
8555-8557 |
TO |
denotes |
to |
T2527 |
8558-8564 |
VB |
denotes |
access |
T2528 |
8565-8568 |
PRP$ |
denotes |
its |
T2529 |
8569-8575 |
NN |
denotes |
target |
T2530 |
8576-8581 |
NNS |
denotes |
genes |
T2531 |
8581-8582 |
. |
denotes |
. |
T2532 |
8583-8591 |
JJ |
denotes |
Enhanced |
T2533 |
8592-8599 |
JJ |
denotes |
nuclear |
T2534 |
8600-8610 |
NN |
denotes |
expression |
T2535 |
8611-8613 |
IN |
denotes |
of |
T2536 |
8614-8620 |
NN |
denotes |
GATA-3 |
T2537 |
8621-8630 |
VBG |
denotes |
following |
T2538 |
8631-8632 |
NNP |
denotes |
T |
T2539 |
8633-8637 |
NN |
denotes |
cell |
T2540 |
8638-8646 |
NN |
denotes |
receptor |
T2541 |
8647-8657 |
NN |
denotes |
activation |
T2542 |
8658-8661 |
VBD |
denotes |
was |
T2543 |
8662-8667 |
JJ |
denotes |
first |
T2544 |
8668-8680 |
VBN |
denotes |
demonstrated |
T2545 |
8681-8683 |
IN |
denotes |
in |
T2546 |
8684-8690 |
NN |
denotes |
murine |
T2547 |
8691-8692 |
NNP |
denotes |
T |
T2548 |
8693-8698 |
NNS |
denotes |
cells |
T2549 |
8699-8700 |
NNP |
denotes |
[ |
T2550 |
8700-8702 |
CD |
denotes |
13 |
T2551 |
8702-8703 |
NNP |
denotes |
] |
T2552 |
8704-8707 |
CC |
denotes |
and |
T2553 |
8708-8711 |
VBD |
denotes |
was |
T2554 |
8712-8720 |
RB |
denotes |
recently |
T2555 |
8721-8730 |
VBN |
denotes |
confirmed |
T2556 |
8731-8733 |
IN |
denotes |
in |
T2557 |
8734-8739 |
JJ |
denotes |
human |
T2558 |
8740-8741 |
NNP |
denotes |
T |
T2559 |
8742-8747 |
NNS |
denotes |
cells |
T2560 |
8748-8757 |
VBG |
denotes |
following |
T2561 |
8758-8759 |
NNP |
denotes |
T |
T2562 |
8760-8764 |
NN |
denotes |
cell |
T2563 |
8765-8773 |
NN |
denotes |
receptor |
T2564 |
8774-8777 |
CC |
denotes |
and |
T2565 |
8778-8789 |
NN |
denotes |
co-receptor |
T2566 |
8790-8801 |
NN |
denotes |
stimulation |
T2567 |
8802-8803 |
NNP |
denotes |
[ |
T2568 |
8803-8805 |
CD |
denotes |
12 |
T2569 |
8805-8806 |
NNP |
denotes |
] |
T2570 |
8806-8807 |
. |
denotes |
. |
T2571 |
8808-8814 |
JJ |
denotes |
GATA-3 |
T2572 |
8815-8823 |
VBZ |
denotes |
contains |
T2573 |
8824-8825 |
DT |
denotes |
a |
T2574 |
8826-8835 |
JJ |
denotes |
classical |
T2575 |
8836-8843 |
JJ |
denotes |
nuclear |
T2576 |
8844-8850 |
NN |
denotes |
import |
T2577 |
8851-8857 |
NN |
denotes |
signal |
T2578 |
8858-8859 |
NNP |
denotes |
[ |
T2579 |
8859-8861 |
CD |
denotes |
14 |
T2580 |
8861-8862 |
NNP |
denotes |
] |
T2581 |
8863-8866 |
CC |
denotes |
and |
T2582 |
8867-8869 |
VBZ |
denotes |
is |
T2583 |
8870-8881 |
VBN |
denotes |
transported |
T2584 |
8882-8886 |
IN |
denotes |
into |
T2585 |
8887-8890 |
DT |
denotes |
the |
T2586 |
8891-8898 |
NN |
denotes |
nucleus |
T2587 |
8899-8901 |
IN |
denotes |
by |
T2588 |
8902-8905 |
DT |
denotes |
the |
T2589 |
8906-8913 |
JJ |
denotes |
nuclear |
T2590 |
8914-8920 |
NN |
denotes |
import |
T2591 |
8921-8928 |
NN |
denotes |
protein |
T2592 |
8929-8939 |
NN |
denotes |
importin-α |
T2593 |
8940-8941 |
-LRB- |
denotes |
( |
T2594 |
8941-8945 |
RB |
denotes |
also |
T2595 |
8946-8951 |
VBN |
denotes |
known |
T2596 |
8952-8954 |
IN |
denotes |
as |
T2597 |
8955-8968 |
NN |
denotes |
karyopherin-α |
T2598 |
8968-8969 |
-RRB- |
denotes |
) |
T2599 |
8970-8971 |
NNP |
denotes |
[ |
T2600 |
8971-8973 |
CD |
denotes |
12 |
T2601 |
8973-8974 |
NNP |
denotes |
] |
T2602 |
8974-8975 |
. |
denotes |
. |
T2603 |
8976-8984 |
NN |
denotes |
Deletion |
T2604 |
8985-8987 |
IN |
denotes |
of |
T2605 |
8988-8989 |
DT |
denotes |
a |
T2606 |
8990-8996 |
NN |
denotes |
region |
T2607 |
8997-9009 |
VBG |
denotes |
encompassing |
T2608 |
9010-9013 |
DT |
denotes |
the |
T2609 |
9014-9020 |
JJ |
denotes |
GATA-3 |
T2610 |
9021-9028 |
JJ |
denotes |
nuclear |
T2611 |
9029-9041 |
NN |
denotes |
localisation |
T2612 |
9042-9050 |
NN |
denotes |
sequence |
T2613 |
9051-9052 |
-LRB- |
denotes |
( |
T2614 |
9052-9055 |
NNP |
denotes |
NLS |
T2615 |
9055-9056 |
-RRB- |
denotes |
) |
T2616 |
9057-9063 |
NN |
denotes |
region |
T2617 |
9064-9066 |
IN |
denotes |
in |
T2618 |
9067-9073 |
NN |
denotes |
murine |
T2619 |
9074-9077 |
CC |
denotes |
and |
T2620 |
9078-9083 |
JJ |
denotes |
human |
T2621 |
9084-9089 |
NNS |
denotes |
cells |
T2622 |
9090-9098 |
VBZ |
denotes |
prevents |
T2623 |
9099-9102 |
PRP$ |
denotes |
its |
T2624 |
9103-9110 |
JJ |
denotes |
nuclear |
T2625 |
9111-9123 |
NN |
denotes |
localisation |
T2626 |
9124-9125 |
NNP |
denotes |
[ |
T2627 |
9125-9127 |
CD |
denotes |
12 |
T2628 |
9127-9128 |
NNP |
denotes |
] |
T2629 |
9128-9129 |
, |
denotes |
, |
T2630 |
9129-9130 |
NNP |
denotes |
[ |
T2631 |
9130-9132 |
CD |
denotes |
14 |
T2632 |
9132-9133 |
NNP |
denotes |
] |
T2633 |
9133-9134 |
. |
denotes |
. |
T2634 |
9135-9138 |
DT |
denotes |
The |
T2635 |
9139-9147 |
NN |
denotes |
affinity |
T2636 |
9148-9150 |
IN |
denotes |
of |
T2637 |
9151-9154 |
DT |
denotes |
the |
T2638 |
9155-9165 |
JJ |
denotes |
importin-α |
T2639 |
9166-9169 |
NNP |
denotes |
NLS |
T2640 |
9170-9181 |
NN |
denotes |
interaction |
T2641 |
9182-9184 |
VBZ |
denotes |
is |
T2642 |
9185-9194 |
VBN |
denotes |
regulated |
T2643 |
9195-9197 |
IN |
denotes |
by |
T2644 |
9198-9213 |
NN |
denotes |
phosphorylation |
T2645 |
9214-9215 |
NNP |
denotes |
[ |
T2646 |
9215-9217 |
CD |
denotes |
15 |
T2647 |
9217-9218 |
NNP |
denotes |
] |
T2648 |
9218-9219 |
, |
denotes |
, |
T2649 |
9220-9223 |
CC |
denotes |
and |
T2650 |
9224-9226 |
PRP |
denotes |
we |
T2651 |
9227-9231 |
VBP |
denotes |
have |
T2652 |
9232-9237 |
VBN |
denotes |
shown |
T2653 |
9238-9242 |
IN |
denotes |
that |
T2654 |
9243-9246 |
CD |
denotes |
p38 |
T2655 |
9247-9264 |
JJ |
denotes |
mitogen-activated |
T2656 |
9265-9272 |
NN |
denotes |
protein |
T2657 |
9273-9279 |
NN |
denotes |
kinase |
T2658 |
9280-9281 |
-LRB- |
denotes |
( |
T2659 |
9281-9285 |
NNP |
denotes |
MAPK |
T2660 |
9285-9286 |
-RRB- |
denotes |
) |
T2661 |
9287-9292 |
VBZ |
denotes |
plays |
T2662 |
9293-9294 |
DT |
denotes |
a |
T2663 |
9295-9303 |
JJ |
denotes |
critical |
T2664 |
9304-9308 |
NN |
denotes |
role |
T2665 |
9309-9311 |
IN |
denotes |
in |
T2666 |
9312-9327 |
VBG |
denotes |
phosphorylating |
T2667 |
9328-9334 |
NN |
denotes |
GATA-3 |
T2668 |
9335-9337 |
TO |
denotes |
to |
T2669 |
9338-9345 |
VB |
denotes |
enhance |
T2670 |
9346-9349 |
PRP$ |
denotes |
its |
T2671 |
9350-9361 |
NN |
denotes |
interaction |
T2672 |
9362-9366 |
IN |
denotes |
with |
T2673 |
9367-9377 |
JJ |
denotes |
importin-α |
T2674 |
9378-9381 |
CC |
denotes |
and |
T2675 |
9382-9392 |
JJ |
denotes |
subsequent |
T2676 |
9393-9402 |
NN |
denotes |
transport |
T2677 |
9403-9407 |
IN |
denotes |
into |
T2678 |
9408-9411 |
DT |
denotes |
the |
T2679 |
9412-9419 |
NN |
denotes |
nucleus |
T2680 |
9420-9421 |
NNP |
denotes |
[ |
T2681 |
9421-9423 |
CD |
denotes |
12 |
T2682 |
9423-9424 |
NNP |
denotes |
] |
T2683 |
9424-9425 |
. |
denotes |
. |
T2684 |
9426-9441 |
NNS |
denotes |
Corticosteroids |
T2685 |
9442-9445 |
VBP |
denotes |
are |
T2686 |
9446-9452 |
RB |
denotes |
highly |
T2687 |
9453-9462 |
JJ |
denotes |
effective |
T2688 |
9463-9465 |
IN |
denotes |
in |
T2689 |
9466-9469 |
DT |
denotes |
the |
T2690 |
9470-9479 |
NN |
denotes |
treatment |
T2691 |
9480-9482 |
IN |
denotes |
of |
T2692 |
9483-9491 |
JJ |
denotes |
allergic |
T2693 |
9492-9504 |
NN |
denotes |
inflammation |
T2694 |
9504-9505 |
, |
denotes |
, |
T2695 |
9506-9510 |
IN |
denotes |
with |
T2696 |
9511-9517 |
JJ |
denotes |
marked |
T2697 |
9518-9529 |
NN |
denotes |
suppression |
T2698 |
9530-9532 |
IN |
denotes |
of |
T2699 |
9533-9536 |
JJ |
denotes |
Th2 |
T2700 |
9537-9546 |
NNS |
denotes |
cytokines |
T2701 |
9547-9549 |
IN |
denotes |
in |
T2702 |
9550-9557 |
NNS |
denotes |
airways |
T2703 |
9558-9560 |
IN |
denotes |
of |
T2704 |
9561-9569 |
NNS |
denotes |
patients |
T2705 |
9570-9574 |
IN |
denotes |
with |
T2706 |
9575-9581 |
NN |
denotes |
asthma |
T2707 |
9582-9583 |
NNP |
denotes |
[ |
T2708 |
9583-9585 |
CD |
denotes |
16 |
T2709 |
9585-9586 |
NNP |
denotes |
] |
T2710 |
9586-9587 |
. |
denotes |
. |
T2711 |
9588-9603 |
NNS |
denotes |
Corticosteroids |
T2712 |
9604-9611 |
VBP |
denotes |
mediate |
T2713 |
9612-9617 |
PRP$ |
denotes |
their |
T2714 |
9618-9635 |
JJ |
denotes |
anti-inflammatory |
T2715 |
9636-9643 |
NNS |
denotes |
effects |
T2716 |
9644-9651 |
IN |
denotes |
through |
T2717 |
9652-9659 |
JJ |
denotes |
binding |
T2718 |
9660-9662 |
TO |
denotes |
to |
T2719 |
9663-9677 |
JJ |
denotes |
glucocorticoid |
T2720 |
9678-9687 |
NNS |
denotes |
receptors |
T2721 |
9688-9689 |
-LRB- |
denotes |
( |
T2722 |
9689-9692 |
NNS |
denotes |
GRs |
T2723 |
9692-9693 |
-RRB- |
denotes |
) |
T2724 |
9693-9694 |
, |
denotes |
, |
T2725 |
9695-9700 |
WDT |
denotes |
which |
T2726 |
9701-9705 |
RB |
denotes |
then |
T2727 |
9706-9717 |
VBP |
denotes |
translocate |
T2728 |
9718-9720 |
TO |
denotes |
to |
T2729 |
9721-9724 |
DT |
denotes |
the |
T2730 |
9725-9732 |
NN |
denotes |
nucleus |
T2731 |
9733-9738 |
WRB |
denotes |
where |
T2732 |
9739-9743 |
PRP |
denotes |
they |
T2733 |
9744-9752 |
VBP |
denotes |
interact |
T2734 |
9753-9757 |
IN |
denotes |
with |
T2735 |
9758-9772 |
JJ |
denotes |
glucocorticoid |
T2736 |
9773-9781 |
NN |
denotes |
response |
T2737 |
9782-9790 |
NNS |
denotes |
elements |
T2738 |
9791-9792 |
-LRB- |
denotes |
( |
T2739 |
9792-9796 |
NNS |
denotes |
GREs |
T2740 |
9796-9797 |
-RRB- |
denotes |
) |
T2741 |
9798-9800 |
IN |
denotes |
in |
T2742 |
9801-9804 |
DT |
denotes |
the |
T2743 |
9805-9813 |
NN |
denotes |
promoter |
T2744 |
9814-9821 |
NNS |
denotes |
regions |
T2745 |
9822-9824 |
IN |
denotes |
of |
T2746 |
9825-9842 |
JJ |
denotes |
steroid-sensitive |
T2747 |
9843-9848 |
NNS |
denotes |
genes |
T2748 |
9848-9849 |
. |
denotes |
. |
T2749 |
9850-9863 |
RB |
denotes |
Alternatively |
T2750 |
9863-9864 |
, |
denotes |
, |
T2751 |
9865-9874 |
VBN |
denotes |
activated |
T2752 |
9875-9877 |
NNP |
denotes |
GR |
T2753 |
9878-9887 |
NNS |
denotes |
interacts |
T2754 |
9888-9892 |
IN |
denotes |
with |
T2755 |
9893-9904 |
NN |
denotes |
coactivator |
T2756 |
9905-9914 |
NNS |
denotes |
molecules |
T2757 |
9915-9917 |
TO |
denotes |
to |
T2758 |
9918-9926 |
VB |
denotes |
suppress |
T2759 |
9927-9930 |
DT |
denotes |
the |
T2760 |
9931-9941 |
NN |
denotes |
expression |
T2761 |
9942-9944 |
IN |
denotes |
of |
T2762 |
9945-9957 |
JJ |
denotes |
inflammatory |
T2763 |
9958-9963 |
NNS |
denotes |
genes |
T2764 |
9964-9966 |
IN |
denotes |
by |
T2765 |
9967-9977 |
VBG |
denotes |
inhibiting |
T2766 |
9978-9981 |
DT |
denotes |
the |
T2767 |
9982-9988 |
NN |
denotes |
action |
T2768 |
9989-9991 |
IN |
denotes |
of |
T2769 |
9992-10007 |
JJ |
denotes |
proinflammatory |
T2770 |
10008-10021 |
NN |
denotes |
transcription |
T2771 |
10022-10029 |
NNS |
denotes |
factors |
T2772 |
10030-10034 |
JJ |
denotes |
such |
T2773 |
10035-10037 |
IN |
denotes |
as |
T2774 |
10038-10045 |
JJ |
denotes |
nuclear |
T2775 |
10046-10055 |
NNP |
denotes |
factor-κB |
T2776 |
10056-10057 |
-LRB- |
denotes |
( |
T2777 |
10057-10062 |
NNP |
denotes |
NF-κB |
T2778 |
10062-10063 |
-RRB- |
denotes |
) |
T2779 |
10064-10071 |
IN |
denotes |
through |
T2780 |
10072-10075 |
DT |
denotes |
the |
T2781 |
10076-10087 |
NN |
denotes |
recruitment |
T2782 |
10088-10090 |
IN |
denotes |
of |
T2783 |
10091-10103 |
NN |
denotes |
co-repressor |
T2784 |
10104-10113 |
NNS |
denotes |
molecules |
T2785 |
10114-10118 |
JJ |
denotes |
such |
T2786 |
10119-10121 |
IN |
denotes |
as |
T2787 |
10122-10129 |
NN |
denotes |
histone |
T2788 |
10130-10143 |
JJ |
denotes |
deacetylase-2 |
T2789 |
10144-10145 |
NNP |
denotes |
[ |
T2790 |
10145-10147 |
CD |
denotes |
17 |
T2791 |
10147-10148 |
NNP |
denotes |
] |
T2792 |
10148-10149 |
, |
denotes |
, |
T2793 |
10149-10150 |
NNP |
denotes |
[ |
T2794 |
10150-10152 |
CD |
denotes |
18 |
T2795 |
10152-10153 |
NNP |
denotes |
] |
T2796 |
10153-10154 |
. |
denotes |
. |
T2797 |
10155-10162 |
NNP |
denotes |
Nuclear |
T2798 |
10163-10175 |
NN |
denotes |
localisation |
T2799 |
10176-10179 |
CC |
denotes |
and |
T2800 |
10180-10189 |
NN |
denotes |
retention |
T2801 |
10190-10192 |
IN |
denotes |
of |
T2802 |
10193-10195 |
NNP |
denotes |
GR |
T2803 |
10196-10198 |
VBZ |
denotes |
is |
T2804 |
10199-10207 |
VBN |
denotes |
mediated |
T2805 |
10208-10215 |
IN |
denotes |
through |
T2806 |
10216-10219 |
DT |
denotes |
the |
T2807 |
10220-10227 |
JJ |
denotes |
nuclear |
T2808 |
10228-10240 |
NN |
denotes |
localisation |
T2809 |
10241-10250 |
NNS |
denotes |
sequences |
T2810 |
10251-10254 |
NNP |
denotes |
NL1 |
T2811 |
10255-10258 |
CC |
denotes |
and |
T2812 |
10259-10262 |
NNP |
denotes |
NL2 |
T2813 |
10263-10264 |
NNP |
denotes |
[ |
T2814 |
10264-10266 |
CD |
denotes |
19 |
T2815 |
10266-10267 |
NNP |
denotes |
] |
T2816 |
10267-10268 |
, |
denotes |
, |
T2817 |
10269-10271 |
IN |
denotes |
by |
T2818 |
10272-10279 |
JJ |
denotes |
nuclear |
T2819 |
10280-10289 |
NN |
denotes |
retention |
T2820 |
10290-10297 |
VBZ |
denotes |
signals |
T2821 |
10298-10299 |
NNP |
denotes |
[ |
T2822 |
10299-10301 |
CD |
denotes |
20 |
T2823 |
10301-10302 |
NNP |
denotes |
] |
T2824 |
10302-10303 |
, |
denotes |
, |
T2825 |
10304-10307 |
CC |
denotes |
and |
T2826 |
10308-10310 |
IN |
denotes |
by |
T2827 |
10311-10318 |
NN |
denotes |
control |
T2828 |
10319-10321 |
IN |
denotes |
of |
T2829 |
10322-10329 |
JJ |
denotes |
nuclear |
T2830 |
10330-10336 |
NN |
denotes |
export |
T2831 |
10337-10340 |
IN |
denotes |
via |
T2832 |
10341-10342 |
DT |
denotes |
a |
T2833 |
10343-10354 |
JJ |
denotes |
chromosomal |
T2834 |
10355-10361 |
NN |
denotes |
region |
T2835 |
10362-10373 |
NN |
denotes |
maintenance |
T2836 |
10374-10375 |
CD |
denotes |
1 |
T2837 |
10376-10377 |
-LRB- |
denotes |
( |
T2838 |
10377-10382 |
NN |
denotes |
CRM-1 |
T2839 |
10382-10383 |
-RRB- |
denotes |
) |
T2840 |
10384-10393 |
JJ |
denotes |
dependent |
T2841 |
10394-10401 |
NN |
denotes |
pathway |
T2842 |
10402-10403 |
NNP |
denotes |
[ |
T2843 |
10403-10405 |
CD |
denotes |
21 |
T2844 |
10405-10406 |
NNP |
denotes |
] |
T2845 |
10406-10407 |
. |
denotes |
. |
T2846 |
10408-10411 |
CD |
denotes |
NL1 |
T2847 |
10411-10412 |
, |
denotes |
, |
T2848 |
10413-10418 |
WDT |
denotes |
which |
T2849 |
10419-10421 |
VBZ |
denotes |
is |
T2850 |
10422-10429 |
JJ |
denotes |
similar |
T2851 |
10430-10432 |
TO |
denotes |
to |
T2852 |
10433-10436 |
DT |
denotes |
the |
T2853 |
10437-10441 |
NNP |
denotes |
SV40 |
T2854 |
10442-10445 |
NNP |
denotes |
NLS |
T2855 |
10445-10446 |
, |
denotes |
, |
T2856 |
10447-10452 |
VBZ |
denotes |
binds |
T2857 |
10453-10455 |
TO |
denotes |
to |
T2858 |
10456-10466 |
VB |
denotes |
importin-α |
T2859 |
10467-10468 |
NNP |
denotes |
[ |
T2860 |
10468-10470 |
CD |
denotes |
22 |
T2861 |
10470-10471 |
NNP |
denotes |
] |
T2862 |
10471-10472 |
. |
denotes |
. |
T2863 |
10473-10476 |
CD |
denotes |
NL1 |
T2864 |
10477-10479 |
VBZ |
denotes |
is |
T2865 |
10480-10489 |
VBN |
denotes |
activated |
T2866 |
10490-10494 |
DT |
denotes |
both |
T2867 |
10495-10497 |
IN |
denotes |
by |
T2868 |
10498-10512 |
JJ |
denotes |
glucocorticoid |
T2869 |
10513-10521 |
NNS |
denotes |
agonists |
T2870 |
10522-10526 |
JJ |
denotes |
such |
T2871 |
10527-10529 |
IN |
denotes |
as |
T2872 |
10530-10543 |
NN |
denotes |
dexamethasone |
T2873 |
10544-10547 |
CC |
denotes |
and |
T2874 |
10548-10559 |
NN |
denotes |
fluticasone |
T2875 |
10560-10570 |
NN |
denotes |
propionate |
T2876 |
10571-10572 |
-LRB- |
denotes |
( |
T2877 |
10572-10574 |
NNP |
denotes |
FP |
T2878 |
10574-10575 |
-RRB- |
denotes |
) |
T2879 |
10576-10579 |
CC |
denotes |
and |
T2880 |
10580-10582 |
IN |
denotes |
by |
T2881 |
10583-10597 |
JJ |
denotes |
glucocorticoid |
T2882 |
10598-10609 |
NNS |
denotes |
antagonists |
T2883 |
10610-10614 |
JJ |
denotes |
such |
T2884 |
10615-10617 |
IN |
denotes |
as |
T2885 |
10618-10630 |
NN |
denotes |
mifepristone |
T2886 |
10631-10632 |
-LRB- |
denotes |
( |
T2887 |
10632-10637 |
NNP |
denotes |
RU486 |
T2888 |
10637-10638 |
-RRB- |
denotes |
) |
T2889 |
10639-10640 |
NNP |
denotes |
[ |
T2890 |
10640-10642 |
CD |
denotes |
23 |
T2891 |
10642-10643 |
NNP |
denotes |
] |
T2892 |
10643-10644 |
. |
denotes |
. |
T2893 |
10645-10648 |
CD |
denotes |
NL1 |
T2894 |
10649-10652 |
MD |
denotes |
can |
T2895 |
10653-10655 |
VB |
denotes |
be |
T2896 |
10656-10663 |
VBN |
denotes |
mutated |
T2897 |
10663-10664 |
, |
denotes |
, |
T2898 |
10665-10668 |
CC |
denotes |
and |
T2899 |
10669-10672 |
DT |
denotes |
the |
T2900 |
10673-10682 |
VBG |
denotes |
resulting |
T2901 |
10683-10685 |
NNP |
denotes |
GR |
T2902 |
10686-10691 |
RB |
denotes |
still |
T2903 |
10692-10704 |
VBZ |
denotes |
translocates |
T2904 |
10705-10707 |
TO |
denotes |
to |
T2905 |
10708-10711 |
DT |
denotes |
the |
T2906 |
10712-10719 |
NN |
denotes |
nucleus |
T2907 |
10720-10722 |
IN |
denotes |
in |
T2908 |
10723-10731 |
NN |
denotes |
response |
T2909 |
10732-10734 |
TO |
denotes |
to |
T2910 |
10735-10742 |
NNS |
denotes |
ligands |
T2911 |
10742-10743 |
, |
denotes |
, |
T2912 |
10744-10747 |
CC |
denotes |
but |
T2913 |
10748-10751 |
IN |
denotes |
via |
T2914 |
10752-10763 |
NN |
denotes |
interaction |
T2915 |
10764-10768 |
IN |
denotes |
with |
T2916 |
10769-10777 |
NN |
denotes |
importin |
T2917 |
10778-10779 |
CD |
denotes |
7 |
T2918 |
10779-10780 |
, |
denotes |
, |
T2919 |
10781-10783 |
DT |
denotes |
an |
T2920 |
10784-10789 |
NN |
denotes |
event |
T2921 |
10790-10794 |
WDT |
denotes |
that |
T2922 |
10795-10803 |
VBZ |
denotes |
requires |
T2923 |
10804-10806 |
DT |
denotes |
an |
T2924 |
10807-10813 |
RB |
denotes |
as-yet |
T2925 |
10814-10821 |
JJ |
denotes |
unknown |
T2926 |
10822-10831 |
NN |
denotes |
component |
T2927 |
10832-10833 |
NNP |
denotes |
[ |
T2928 |
10833-10835 |
CD |
denotes |
23 |
T2929 |
10835-10836 |
NNP |
denotes |
] |
T2930 |
10836-10837 |
. |
denotes |
. |
T2931 |
10838-10841 |
CD |
denotes |
NL2 |
T2932 |
10842-10844 |
VBZ |
denotes |
is |
T2933 |
10845-10851 |
RB |
denotes |
poorly |
T2934 |
10852-10859 |
VBN |
denotes |
defined |
T2935 |
10859-10860 |
, |
denotes |
, |
T2936 |
10861-10869 |
VBG |
denotes |
residing |
T2937 |
10870-10872 |
IN |
denotes |
in |
T2938 |
10873-10876 |
DT |
denotes |
the |
T2939 |
10877-10891 |
JJ |
denotes |
ligand-binding |
T2940 |
10892-10898 |
NN |
denotes |
domain |
T2941 |
10898-10899 |
, |
denotes |
, |
T2942 |
10900-10903 |
CC |
denotes |
and |
T2943 |
10904-10908 |
RB |
denotes |
much |
T2944 |
10909-10913 |
JJR |
denotes |
less |
T2945 |
10914-10916 |
VBZ |
denotes |
is |
T2946 |
10917-10922 |
VBN |
denotes |
known |
T2947 |
10923-10928 |
IN |
denotes |
about |
T2948 |
10929-10932 |
PRP$ |
denotes |
its |
T2949 |
10933-10942 |
NN |
denotes |
mechanism |
T2950 |
10943-10945 |
IN |
denotes |
of |
T2951 |
10946-10948 |
NNP |
denotes |
GR |
T2952 |
10949-10955 |
NN |
denotes |
import |
T2953 |
10956-10957 |
NNP |
denotes |
[ |
T2954 |
10957-10959 |
CD |
denotes |
24 |
T2955 |
10959-10960 |
NNP |
denotes |
] |
T2956 |
10960-10961 |
. |
denotes |
. |
T2957 |
10962-10963 |
DT |
denotes |
A |
T2958 |
10964-10971 |
NN |
denotes |
variety |
T2959 |
10972-10974 |
IN |
denotes |
of |
T2960 |
10975-10980 |
JJ |
denotes |
other |
T2961 |
10981-10988 |
NNS |
denotes |
factors |
T2962 |
10989-10992 |
VBP |
denotes |
are |
T2963 |
10993-10997 |
RB |
denotes |
also |
T2964 |
10998-11007 |
JJ |
denotes |
important |
T2965 |
11008-11011 |
IN |
denotes |
for |
T2966 |
11012-11015 |
DT |
denotes |
the |
T2967 |
11016-11026 |
NN |
denotes |
regulation |
T2968 |
11027-11029 |
IN |
denotes |
of |
T2969 |
11030-11032 |
NNP |
denotes |
GR |
T2970 |
11033-11043 |
NN |
denotes |
activation |
T2971 |
11044-11047 |
CC |
denotes |
and |
T2972 |
11048-11055 |
JJ |
denotes |
nuclear |
T2973 |
11056-11062 |
NN |
denotes |
import |
T2974 |
11063-11072 |
VBG |
denotes |
including |
T2975 |
11073-11083 |
NNS |
denotes |
chaperones |
T2976 |
11084-11088 |
JJ |
denotes |
such |
T2977 |
11089-11091 |
IN |
denotes |
as |
T2978 |
11092-11097 |
NNP |
denotes |
Hsp90 |
T2979 |
11098-11101 |
CC |
denotes |
and |
T2980 |
11102-11107 |
JJ |
denotes |
other |
T2981 |
11108-11121 |
NNS |
denotes |
immunophilins |
T2982 |
11122-11123 |
NNP |
denotes |
[ |
T2983 |
11123-11125 |
CD |
denotes |
24 |
T2984 |
11125-11126 |
NNP |
denotes |
] |
T2985 |
11127-11128 |
NNP |
denotes |
[ |
T2986 |
11128-11130 |
CD |
denotes |
26 |
T2987 |
11130-11131 |
NNP |
denotes |
] |
T2988 |
11132-11135 |
CC |
denotes |
and |
T2989 |
11136-11149 |
JJ |
denotes |
FK506-binding |
T2990 |
11150-11158 |
NNS |
denotes |
proteins |
T2991 |
11159-11163 |
WDT |
denotes |
that |
T2992 |
11164-11167 |
MD |
denotes |
may |
T2993 |
11168-11170 |
VB |
denotes |
be |
T2994 |
11171-11177 |
VBN |
denotes |
linked |
T2995 |
11178-11180 |
TO |
denotes |
to |
T2996 |
11181-11187 |
VB |
denotes |
dynein |
T2997 |
11188-11194 |
CC |
denotes |
and/or |
T2998 |
11195-11209 |
VB |
denotes |
peptidylprolyl |
T2999 |
11210-11219 |
JJ |
denotes |
isomerase |
T3000 |
11220-11221 |
NNP |
denotes |
[ |
T3001 |
11221-11223 |
CD |
denotes |
27 |
T3002 |
11223-11224 |
NNP |
denotes |
] |
T3003 |
11224-11225 |
, |
denotes |
, |
T3004 |
11225-11226 |
NNP |
denotes |
[ |
T3005 |
11226-11228 |
CD |
denotes |
28 |
T3006 |
11228-11229 |
NNP |
denotes |
] |
T3007 |
11229-11230 |
. |
denotes |
. |
T3008 |
11231-11238 |
RB |
denotes |
However |
T3009 |
11238-11239 |
, |
denotes |
, |
T3010 |
11240-11243 |
DT |
denotes |
the |
T3011 |
11244-11253 |
JJ |
denotes |
molecular |
T3012 |
11254-11259 |
NN |
denotes |
basis |
T3013 |
11260-11263 |
IN |
denotes |
for |
T3014 |
11264-11267 |
DT |
denotes |
the |
T3015 |
11268-11278 |
NN |
denotes |
inhibition |
T3016 |
11279-11281 |
IN |
denotes |
of |
T3017 |
11282-11285 |
JJ |
denotes |
Th2 |
T3018 |
11286-11295 |
NNS |
denotes |
cytokines |
T3019 |
11296-11298 |
IN |
denotes |
by |
T3020 |
11299-11314 |
NNS |
denotes |
corticosteroids |
T3021 |
11315-11317 |
VBZ |
denotes |
is |
T3022 |
11318-11321 |
RB |
denotes |
not |
T3023 |
11322-11326 |
RB |
denotes |
well |
T3024 |
11327-11337 |
VBN |
denotes |
understood |
T3025 |
11337-11338 |
, |
denotes |
, |
T3026 |
11339-11346 |
IN |
denotes |
because |
T3027 |
11347-11350 |
DT |
denotes |
the |
T3028 |
11351-11356 |
NNS |
denotes |
genes |
T3029 |
11357-11365 |
VBG |
denotes |
encoding |
T3030 |
11366-11370 |
NN |
denotes |
IL-4 |
T3031 |
11370-11371 |
, |
denotes |
, |
T3032 |
11372-11376 |
NN |
denotes |
IL-5 |
T3033 |
11376-11377 |
, |
denotes |
, |
T3034 |
11378-11381 |
CC |
denotes |
and |
T3035 |
11382-11387 |
NNP |
denotes |
IL-13 |
T3036 |
11388-11390 |
VBP |
denotes |
do |
T3037 |
11391-11394 |
RB |
denotes |
not |
T3038 |
11395-11399 |
VB |
denotes |
have |
T3039 |
11400-11403 |
DT |
denotes |
any |
T3040 |
11404-11416 |
JJ |
denotes |
recognisable |
T3041 |
11417-11420 |
NNP |
denotes |
GRE |
T3042 |
11421-11429 |
NN |
denotes |
sequence |
T3043 |
11430-11431 |
NNP |
denotes |
[ |
T3044 |
11431-11433 |
CD |
denotes |
29 |
T3045 |
11433-11434 |
NNP |
denotes |
] |
T3046 |
11435-11438 |
CC |
denotes |
and |
T3047 |
11439-11442 |
VBP |
denotes |
are |
T3048 |
11443-11447 |
RB |
denotes |
only |
T3049 |
11448-11454 |
RB |
denotes |
partly |
T3050 |
11455-11464 |
VBN |
denotes |
regulated |
T3051 |
11465-11467 |
IN |
denotes |
by |
T3052 |
11468-11473 |
NNP |
denotes |
NF-κB |
T3053 |
11474-11476 |
IN |
denotes |
in |
T3054 |
11477-11482 |
JJ |
denotes |
human |
T3055 |
11483-11488 |
NNS |
denotes |
cells |
T3056 |
11489-11490 |
NNP |
denotes |
[ |
T3057 |
11490-11492 |
CD |
denotes |
30 |
T3058 |
11492-11493 |
NNP |
denotes |
] |
T3059 |
11494-11495 |
NNP |
denotes |
[ |
T3060 |
11495-11497 |
CD |
denotes |
32 |
T3061 |
11497-11498 |
NNP |
denotes |
] |
T3062 |
11498-11499 |
. |
denotes |
. |
T3063 |
11500-11505 |
VBG |
denotes |
Using |
T3064 |
11506-11520 |
NN |
denotes |
overexpression |
T3065 |
11521-11524 |
CC |
denotes |
and |
T3066 |
11525-11537 |
JJ |
denotes |
CAT-reporter |
T3067 |
11538-11543 |
NNS |
denotes |
genes |
T3068 |
11543-11544 |
, |
denotes |
, |
T3069 |
11545-11553 |
NNP |
denotes |
Lavender |
T3070 |
11554-11557 |
CC |
denotes |
and |
T3071 |
11558-11568 |
NNS |
denotes |
colleagues |
T3072 |
11569-11570 |
NNP |
denotes |
[ |
T3073 |
11570-11572 |
CD |
denotes |
33 |
T3074 |
11572-11573 |
NNP |
denotes |
] |
T3075 |
11574-11578 |
VBP |
denotes |
have |
T3076 |
11579-11584 |
VBN |
denotes |
shown |
T3077 |
11585-11589 |
IN |
denotes |
that |
T3078 |
11590-11592 |
NNP |
denotes |
GR |
T3079 |
11593-11600 |
VBD |
denotes |
reduced |
T3080 |
11601-11616 |
JJ |
denotes |
GATA-3-mediated |
T3081 |
11617-11621 |
NN |
denotes |
IL-5 |
T3082 |
11622-11625 |
CC |
denotes |
and |
T3083 |
11626-11629 |
CD |
denotes |
-13 |
T3084 |
11630-11638 |
NN |
denotes |
promoter |
T3085 |
11639-11647 |
NN |
denotes |
activity |
T3086 |
11648-11650 |
IN |
denotes |
in |
T3087 |
11651-11656 |
JJ |
denotes |
human |
T3088 |
11657-11660 |
NNP |
denotes |
CD4 |
T3089 |
11660-11661 |
CD |
denotes |
+ |
T3090 |
11662-11663 |
NNP |
denotes |
T |
T3091 |
11664-11669 |
NNS |
denotes |
cells |
T3092 |
11669-11670 |
. |
denotes |
. |
T3093 |
11671-11674 |
DT |
denotes |
The |
T3094 |
11675-11682 |
NNS |
denotes |
authors |
T3095 |
11683-11693 |
VBD |
denotes |
postulated |
T3096 |
11694-11698 |
IN |
denotes |
that |
T3097 |
11699-11704 |
JJ |
denotes |
local |
T3098 |
11705-11716 |
NN |
denotes |
recruitment |
T3099 |
11717-11719 |
IN |
denotes |
of |
T3100 |
11720-11722 |
NNP |
denotes |
GR |
T3101 |
11723-11726 |
MD |
denotes |
may |
T3102 |
11727-11732 |
VB |
denotes |
alter |
T3103 |
11733-11736 |
DT |
denotes |
the |
T3104 |
11737-11744 |
NN |
denotes |
ability |
T3105 |
11745-11747 |
IN |
denotes |
of |
T3106 |
11748-11754 |
JJ |
denotes |
GATA-3 |
T3107 |
11755-11761 |
CC |
denotes |
either |
T3108 |
11762-11764 |
TO |
denotes |
to |
T3109 |
11765-11769 |
NN |
denotes |
bind |
T3110 |
11770-11772 |
TO |
denotes |
to |
T3111 |
11773-11776 |
PRP$ |
denotes |
its |
T3112 |
11777-11783 |
NN |
denotes |
target |
T3113 |
11784-11788 |
NN |
denotes |
site |
T3114 |
11788-11789 |
, |
denotes |
, |
T3115 |
11790-11792 |
TO |
denotes |
to |
T3116 |
11793-11798 |
VB |
denotes |
cause |
T3117 |
11799-11814 |
JJ |
denotes |
transcriptional |
T3118 |
11815-11828 |
NN |
denotes |
up-regulation |
T3119 |
11828-11829 |
, |
denotes |
, |
T3120 |
11830-11832 |
CC |
denotes |
or |
T3121 |
11833-11835 |
TO |
denotes |
to |
T3122 |
11836-11844 |
VB |
denotes |
maintain |
T3123 |
11845-11847 |
DT |
denotes |
an |
T3124 |
11848-11859 |
NN |
denotes |
environment |
T3125 |
11860-11864 |
WDT |
denotes |
that |
T3126 |
11865-11867 |
VBZ |
denotes |
is |
T3127 |
11868-11878 |
JJ |
denotes |
permissive |
T3128 |
11879-11882 |
IN |
denotes |
for |
T3129 |
11883-11896 |
NN |
denotes |
transcription |
T3130 |
11896-11897 |
. |
denotes |
. |
T3131 |
11898-11900 |
PRP |
denotes |
We |
T3132 |
11901-11910 |
RB |
denotes |
therefore |
T3133 |
11911-11923 |
VBD |
denotes |
investigated |
T3134 |
11924-11927 |
DT |
denotes |
the |
T3135 |
11928-11935 |
NNS |
denotes |
effects |
T3136 |
11936-11938 |
IN |
denotes |
of |
T3137 |
11939-11940 |
DT |
denotes |
a |
T3138 |
11941-11950 |
JJ |
denotes |
synthetic |
T3139 |
11951-11965 |
NN |
denotes |
corticosteroid |
T3140 |
11965-11966 |
, |
denotes |
, |
T3141 |
11967-11969 |
NNP |
denotes |
FP |
T3142 |
11969-11970 |
, |
denotes |
, |
T3143 |
11971-11973 |
IN |
denotes |
on |
T3144 |
11974-11980 |
JJ |
denotes |
GATA-3 |
T3145 |
11981-11996 |
NN |
denotes |
phosphorylation |
T3146 |
11997-12000 |
CC |
denotes |
and |
T3147 |
12001-12008 |
JJ |
denotes |
nuclear |
T3148 |
12009-12022 |
NN |
denotes |
translocation |
T3149 |
12023-12025 |
IN |
denotes |
in |
T3150 |
12026-12027 |
DT |
denotes |
a |
T3151 |
12028-12029 |
NNP |
denotes |
T |
T3152 |
12030-12040 |
NN |
denotes |
lymphocyte |
T3153 |
12041-12045 |
NN |
denotes |
cell |
T3154 |
12046-12050 |
NN |
denotes |
line |
T3155 |
12051-12052 |
-LRB- |
denotes |
( |
T3156 |
12052-12058 |
JJ |
denotes |
HuT-78 |
T3157 |
12058-12059 |
-RRB- |
denotes |
) |
T3158 |
12060-12063 |
CC |
denotes |
and |
T3159 |
12064-12066 |
IN |
denotes |
in |
T3160 |
12067-12077 |
JJ |
denotes |
peripheral |
T3161 |
12078-12083 |
NN |
denotes |
blood |
T3162 |
12084-12095 |
NN |
denotes |
mononuclear |
T3163 |
12096-12101 |
NNS |
denotes |
cells |
T3164 |
12102-12111 |
VBN |
denotes |
activated |
T3165 |
12112-12114 |
IN |
denotes |
by |
T3166 |
12115-12123 |
JJ |
denotes |
anti-CD3 |
T3167 |
12124-12127 |
CC |
denotes |
and |
T3168 |
12128-12137 |
JJ |
denotes |
anti-CD28 |
T3169 |
12138-12148 |
NNS |
denotes |
antibodies |
T3170 |
12149-12151 |
IN |
denotes |
in |
T3171 |
12152-12157 |
NN |
denotes |
vitro |
T3172 |
12157-12158 |
. |
denotes |
. |
T3173 |
12159-12161 |
PRP |
denotes |
We |
T3174 |
12162-12166 |
RB |
denotes |
also |
T3175 |
12167-12174 |
VBD |
denotes |
studied |
T3176 |
12175-12178 |
DT |
denotes |
the |
T3177 |
12179-12186 |
NNS |
denotes |
effects |
T3178 |
12187-12189 |
IN |
denotes |
of |
T3179 |
12190-12197 |
JJ |
denotes |
inhaled |
T3180 |
12198-12209 |
NN |
denotes |
fluticasone |
T3181 |
12210-12217 |
NN |
denotes |
therapy |
T3182 |
12218-12220 |
IN |
denotes |
on |
T3183 |
12221-12227 |
JJ |
denotes |
GATA-3 |
T3184 |
12228-12239 |
JJ |
denotes |
subcellular |
T3185 |
12240-12252 |
NN |
denotes |
localization |
T3186 |
12253-12255 |
IN |
denotes |
in |
T3187 |
12256-12266 |
JJ |
denotes |
peripheral |
T3188 |
12267-12272 |
NN |
denotes |
blood |
T3189 |
12273-12284 |
NN |
denotes |
mononuclear |
T3190 |
12285-12290 |
NNS |
denotes |
cells |
T3191 |
12291-12292 |
-LRB- |
denotes |
( |
T3192 |
12292-12297 |
NNS |
denotes |
PBMCs |
T3193 |
12297-12298 |
-RRB- |
denotes |
) |
T3194 |
12299-12303 |
IN |
denotes |
from |
T3195 |
12304-12312 |
NNS |
denotes |
patients |
T3196 |
12313-12317 |
IN |
denotes |
with |
T3197 |
12318-12324 |
NN |
denotes |
asthma |
T3198 |
12324-12325 |
. |
denotes |
. |
T3810 |
12350-12362 |
NNS |
denotes |
Participants |
T3811 |
12363-12366 |
CC |
denotes |
and |
T3812 |
12367-12372 |
NNP |
denotes |
Study |
T3813 |
12373-12379 |
NNP |
denotes |
Design |
T3814 |
12380-12382 |
PRP |
denotes |
We |
T3815 |
12383-12390 |
VBD |
denotes |
studied |
T3816 |
12391-12399 |
NNS |
denotes |
patients |
T3817 |
12400-12404 |
IN |
denotes |
with |
T3818 |
12405-12409 |
JJ |
denotes |
mild |
T3819 |
12410-12416 |
NN |
denotes |
asthma |
T3820 |
12417-12420 |
WP |
denotes |
who |
T3821 |
12421-12425 |
VBD |
denotes |
were |
T3822 |
12426-12429 |
RB |
denotes |
not |
T3823 |
12430-12437 |
VBN |
denotes |
treated |
T3824 |
12438-12442 |
IN |
denotes |
with |
T3825 |
12443-12450 |
JJ |
denotes |
inhaled |
T3826 |
12451-12466 |
NNS |
denotes |
corticosteroids |
T3827 |
12467-12470 |
WP |
denotes |
who |
T3828 |
12471-12474 |
VBD |
denotes |
had |
T3829 |
12475-12479 |
VBN |
denotes |
been |
T3830 |
12480-12488 |
VBN |
denotes |
included |
T3831 |
12489-12491 |
IN |
denotes |
in |
T3832 |
12492-12493 |
DT |
denotes |
a |
T3833 |
12494-12504 |
RB |
denotes |
previously |
T3834 |
12505-12513 |
VBN |
denotes |
reported |
T3835 |
12514-12526 |
NN |
denotes |
double-blind |
T3836 |
12526-12527 |
, |
denotes |
, |
T3837 |
12528-12546 |
JJ |
denotes |
placebo-controlled |
T3838 |
12546-12547 |
, |
denotes |
, |
T3839 |
12548-12557 |
JJ |
denotes |
crossover |
T3840 |
12558-12563 |
NN |
denotes |
study |
T3841 |
12564-12568 |
IN |
denotes |
with |
T3842 |
12569-12571 |
NNP |
denotes |
FP |
T3843 |
12572-12573 |
NNP |
denotes |
[ |
T3844 |
12573-12575 |
CD |
denotes |
34 |
T3845 |
12575-12576 |
NNP |
denotes |
] |
T3846 |
12576-12577 |
. |
denotes |
. |
T3847 |
12578-12583 |
CD |
denotes |
Seven |
T3848 |
12584-12592 |
NNS |
denotes |
patients |
T3849 |
12593-12597 |
IN |
denotes |
with |
T3850 |
12598-12602 |
JJ |
denotes |
mild |
T3851 |
12603-12609 |
NN |
denotes |
asthma |
T3852 |
12610-12617 |
VBD |
denotes |
entered |
T3853 |
12618-12621 |
DT |
denotes |
the |
T3854 |
12622-12627 |
NN |
denotes |
study |
T3855 |
12628-12631 |
CC |
denotes |
and |
T3856 |
12632-12636 |
VBD |
denotes |
were |
T3857 |
12637-12647 |
VBN |
denotes |
randomized |
T3858 |
12648-12650 |
TO |
denotes |
to |
T3859 |
12651-12658 |
VB |
denotes |
receive |
T3860 |
12659-12660 |
DT |
denotes |
a |
T3861 |
12661-12667 |
JJ |
denotes |
single |
T3862 |
12668-12678 |
NN |
denotes |
inhalation |
T3863 |
12679-12681 |
IN |
denotes |
of |
T3864 |
12682-12684 |
NNP |
denotes |
FP |
T3865 |
12685-12686 |
-LRB- |
denotes |
( |
T3866 |
12686-12689 |
CD |
denotes |
100 |
T3867 |
12690-12693 |
CC |
denotes |
and |
T3868 |
12694-12697 |
CD |
denotes |
500 |
T3869 |
12698-12700 |
NN |
denotes |
µg |
T3870 |
12700-12701 |
-RRB- |
denotes |
) |
T3871 |
12702-12704 |
CC |
denotes |
or |
T3872 |
12705-12706 |
DT |
denotes |
a |
T3873 |
12707-12714 |
VBN |
denotes |
matched |
T3874 |
12715-12722 |
NN |
denotes |
placebo |
T3875 |
12723-12730 |
NN |
denotes |
control |
T3876 |
12731-12734 |
IN |
denotes |
via |
T3877 |
12735-12736 |
DT |
denotes |
a |
T3878 |
12737-12743 |
NN |
denotes |
spacer |
T3879 |
12744-12751 |
NN |
denotes |
chamber |
T3880 |
12751-12752 |
, |
denotes |
, |
T3881 |
12753-12756 |
CC |
denotes |
and |
T3882 |
12757-12760 |
DT |
denotes |
the |
T3883 |
12761-12766 |
JJ |
denotes |
other |
T3884 |
12767-12776 |
NN |
denotes |
treatment |
T3885 |
12777-12780 |
VBD |
denotes |
was |
T3886 |
12781-12786 |
VBN |
denotes |
given |
T3887 |
12787-12792 |
IN |
denotes |
after |
T3888 |
12793-12794 |
DT |
denotes |
a |
T3889 |
12795-12803 |
JJ |
denotes |
wash-out |
T3890 |
12804-12810 |
NN |
denotes |
period |
T3891 |
12811-12813 |
IN |
denotes |
of |
T3892 |
12814-12816 |
IN |
denotes |
at |
T3893 |
12817-12822 |
JJS |
denotes |
least |
T3894 |
12823-12824 |
CD |
denotes |
6 |
T3895 |
12825-12827 |
NN |
denotes |
d. |
T3896 |
12828-12833 |
NNP |
denotes |
Blood |
T3897 |
12834-12837 |
VBD |
denotes |
was |
T3898 |
12838-12843 |
VBN |
denotes |
taken |
T3899 |
12844-12847 |
IN |
denotes |
for |
T3900 |
12848-12859 |
NN |
denotes |
preparation |
T3901 |
12860-12862 |
IN |
denotes |
of |
T3902 |
12863-12868 |
NNS |
denotes |
PBMCs |
T3903 |
12869-12871 |
IN |
denotes |
at |
T3904 |
12872-12873 |
CD |
denotes |
1 |
T3905 |
12874-12877 |
CC |
denotes |
and |
T3906 |
12878-12879 |
CD |
denotes |
2 |
T3907 |
12880-12881 |
NN |
denotes |
h |
T3908 |
12882-12887 |
IN |
denotes |
after |
T3909 |
12888-12892 |
NN |
denotes |
drug |
T3910 |
12893-12907 |
NN |
denotes |
administration |
T3911 |
12907-12908 |
. |
denotes |
. |
T3912 |
12909-12912 |
DT |
denotes |
All |
T3913 |
12913-12921 |
NNS |
denotes |
patients |
T3914 |
12922-12926 |
VBD |
denotes |
gave |
T3915 |
12927-12935 |
VBN |
denotes |
informed |
T3916 |
12936-12943 |
NN |
denotes |
consent |
T3917 |
12944-12947 |
CC |
denotes |
and |
T3918 |
12948-12951 |
DT |
denotes |
the |
T3919 |
12952-12957 |
NN |
denotes |
study |
T3920 |
12958-12961 |
VBD |
denotes |
was |
T3921 |
12962-12970 |
VBN |
denotes |
approved |
T3922 |
12971-12973 |
IN |
denotes |
by |
T3923 |
12974-12977 |
DT |
denotes |
the |
T3924 |
12978-12984 |
NNPS |
denotes |
Ethics |
T3925 |
12985-12994 |
NNP |
denotes |
Committee |
T3926 |
12995-12997 |
IN |
denotes |
of |
T3927 |
12998-13001 |
DT |
denotes |
the |
T3928 |
13002-13007 |
NNP |
denotes |
Royal |
T3929 |
13008-13016 |
NNP |
denotes |
Brompton |
T3930 |
13017-13020 |
CC |
denotes |
and |
T3931 |
13021-13030 |
NNP |
denotes |
Harefield |
T3932 |
13031-13040 |
NNPS |
denotes |
Hospitals |
T3933 |
13041-13044 |
NNP |
denotes |
NHS |
T3934 |
13045-13050 |
NNP |
denotes |
Trust |
T3935 |
13050-13051 |
. |
denotes |
. |
T3936 |
13052-13055 |
DT |
denotes |
The |
T3937 |
13056-13064 |
JJ |
denotes |
clinical |
T3938 |
13065-13070 |
NN |
denotes |
study |
T3939 |
13071-13074 |
VBD |
denotes |
was |
T3940 |
13075-13084 |
VBN |
denotes |
conducted |
T3941 |
13085-13091 |
IN |
denotes |
before |
T3942 |
13092-13095 |
DT |
denotes |
the |
T3943 |
13096-13107 |
NN |
denotes |
requirement |
T3944 |
13108-13111 |
IN |
denotes |
for |
T3945 |
13112-13120 |
NNP |
denotes |
Clinical |
T3946 |
13121-13126 |
NNP |
denotes |
Trial |
T3947 |
13127-13139 |
NNP |
denotes |
Registration |
T3948 |
13139-13140 |
. |
denotes |
. |
T4142 |
13142-13152 |
NNS |
denotes |
Antibodies |
T4143 |
13153-13156 |
CC |
denotes |
and |
T4144 |
13157-13165 |
NNS |
denotes |
Reagents |
T4145 |
13166-13169 |
DT |
denotes |
The |
T4146 |
13170-13180 |
JJ |
denotes |
monoclonal |
T4147 |
13181-13191 |
NNS |
denotes |
antibodies |
T4148 |
13192-13199 |
IN |
denotes |
against |
T4149 |
13200-13205 |
JJ |
denotes |
human |
T4150 |
13206-13209 |
NNP |
denotes |
CD3 |
T4151 |
13209-13210 |
, |
denotes |
, |
T4152 |
13211-13215 |
NNP |
denotes |
CD28 |
T4153 |
13215-13216 |
, |
denotes |
, |
T4154 |
13217-13219 |
NNP |
denotes |
GR |
T4155 |
13219-13220 |
, |
denotes |
, |
T4156 |
13221-13224 |
CC |
denotes |
and |
T4157 |
13225-13235 |
JJ |
denotes |
importin-α |
T4158 |
13236-13240 |
VBD |
denotes |
were |
T4159 |
13241-13250 |
VBN |
denotes |
purchased |
T4160 |
13251-13255 |
IN |
denotes |
from |
T4161 |
13256-13258 |
NNP |
denotes |
BD |
T4162 |
13259-13270 |
NNP |
denotes |
Biosciences |
T4163 |
13271-13272 |
-LRB- |
denotes |
( |
T4164 |
13272-13278 |
NNP |
denotes |
Oxford |
T4165 |
13278-13279 |
, |
denotes |
, |
T4166 |
13280-13286 |
NNP |
denotes |
United |
T4167 |
13287-13294 |
NNP |
denotes |
Kingdom |
T4168 |
13294-13295 |
-RRB- |
denotes |
) |
T4169 |
13295-13296 |
. |
denotes |
. |
T4170 |
13297-13303 |
NN |
denotes |
Rabbit |
T4171 |
13304-13314 |
NNS |
denotes |
antibodies |
T4172 |
13315-13322 |
IN |
denotes |
against |
T4173 |
13323-13328 |
JJ |
denotes |
human |
T4174 |
13329-13335 |
NNP |
denotes |
GATA-3 |
T4175 |
13336-13337 |
-LRB- |
denotes |
( |
T4176 |
13337-13341 |
NNP |
denotes |
H-48 |
T4177 |
13341-13342 |
-RRB- |
denotes |
) |
T4178 |
13343-13346 |
CC |
denotes |
and |
T4179 |
13347-13349 |
NNP |
denotes |
GR |
T4180 |
13350-13351 |
-LRB- |
denotes |
( |
T4181 |
13351-13355 |
NNP |
denotes |
E-20 |
T4182 |
13355-13356 |
, |
denotes |
, |
T4183 |
13357-13364 |
JJ |
denotes |
sc-1003 |
T4184 |
13364-13365 |
-RRB- |
denotes |
) |
T4185 |
13366-13370 |
VBD |
denotes |
were |
T4186 |
13371-13379 |
VBN |
denotes |
obtained |
T4187 |
13380-13384 |
IN |
denotes |
from |
T4188 |
13385-13390 |
NNP |
denotes |
Santa |
T4189 |
13391-13395 |
NNP |
denotes |
Cruz |
T4190 |
13396-13409 |
NNP |
denotes |
Biotechnology |
T4191 |
13410-13411 |
-LRB- |
denotes |
( |
T4192 |
13411-13416 |
NNP |
denotes |
Santa |
T4193 |
13417-13421 |
NNP |
denotes |
Cruz |
T4194 |
13421-13422 |
, |
denotes |
, |
T4195 |
13423-13433 |
NNP |
denotes |
California |
T4196 |
13433-13434 |
, |
denotes |
, |
T4197 |
13435-13441 |
NNP |
denotes |
United |
T4198 |
13442-13448 |
NNPS |
denotes |
States |
T4199 |
13448-13449 |
-RRB- |
denotes |
) |
T4200 |
13449-13450 |
, |
denotes |
, |
T4201 |
13451-13461 |
JJ |
denotes |
polyclonal |
T4202 |
13462-13468 |
NN |
denotes |
rabbit |
T4203 |
13469-13479 |
NNS |
denotes |
antibodies |
T4204 |
13480-13487 |
IN |
denotes |
against |
T4205 |
13488-13499 |
JJ |
denotes |
phospho-p38 |
T4206 |
13500-13503 |
NNP |
denotes |
MAP |
T4207 |
13504-13510 |
NN |
denotes |
kinase |
T4208 |
13511-13514 |
CC |
denotes |
and |
T4209 |
13515-13528 |
NN |
denotes |
phospho-ATF-2 |
T4210 |
13529-13533 |
IN |
denotes |
from |
T4211 |
13534-13538 |
NNP |
denotes |
Cell |
T4212 |
13539-13548 |
NNP |
denotes |
Signaling |
T4213 |
13549-13559 |
NNP |
denotes |
Technology |
T4214 |
13560-13561 |
-LRB- |
denotes |
( |
T4215 |
13561-13564 |
NNP |
denotes |
New |
T4216 |
13565-13572 |
NNP |
denotes |
England |
T4217 |
13573-13580 |
NNPS |
denotes |
Biolabs |
T4218 |
13580-13581 |
, |
denotes |
, |
T4219 |
13582-13590 |
NNP |
denotes |
Hertford |
T4220 |
13590-13591 |
, |
denotes |
, |
T4221 |
13592-13594 |
NNP |
denotes |
UK |
T4222 |
13594-13595 |
-RRB- |
denotes |
) |
T4223 |
13595-13596 |
, |
denotes |
, |
T4224 |
13597-13607 |
JJ |
denotes |
monoclonal |
T4225 |
13608-13616 |
NN |
denotes |
antibody |
T4226 |
13617-13624 |
IN |
denotes |
against |
T4227 |
13625-13638 |
NN |
denotes |
phosphoserine |
T4228 |
13639-13640 |
-LRB- |
denotes |
( |
T4229 |
13640-13645 |
JJ |
denotes |
clone |
T4230 |
13646-13649 |
NNP |
denotes |
4H4 |
T4231 |
13649-13650 |
-RRB- |
denotes |
) |
T4232 |
13651-13655 |
IN |
denotes |
from |
T4233 |
13656-13664 |
NNP |
denotes |
Affiniti |
T4234 |
13665-13673 |
NNP |
denotes |
Research |
T4235 |
13674-13682 |
NNP |
denotes |
Products |
T4236 |
13683-13684 |
-LRB- |
denotes |
( |
T4237 |
13684-13690 |
NNP |
denotes |
Exeter |
T4238 |
13690-13691 |
, |
denotes |
, |
T4239 |
13692-13694 |
NNP |
denotes |
UK |
T4240 |
13694-13695 |
-RRB- |
denotes |
) |
T4241 |
13695-13696 |
, |
denotes |
, |
T4242 |
13697-13700 |
CC |
denotes |
and |
T4243 |
13701-13711 |
NNS |
denotes |
antibodies |
T4244 |
13712-13719 |
IN |
denotes |
against |
T4245 |
13720-13726 |
NN |
denotes |
rabbit |
T4246 |
13727-13741 |
NNP |
denotes |
IgG-conjugated |
T4247 |
13742-13747 |
NNP |
denotes |
TRITC |
T4248 |
13748-13752 |
IN |
denotes |
from |
T4249 |
13753-13757 |
NNP |
denotes |
Dako |
T4250 |
13758-13768 |
NNP |
denotes |
Cytomation |
T4251 |
13769-13770 |
-LRB- |
denotes |
( |
T4252 |
13770-13779 |
NNP |
denotes |
Cambridge |
T4253 |
13779-13780 |
, |
denotes |
, |
T4254 |
13781-13783 |
NNP |
denotes |
UK |
T4255 |
13783-13784 |
-RRB- |
denotes |
) |
T4256 |
13784-13785 |
. |
denotes |
. |
T4257 |
13786-13789 |
DT |
denotes |
The |
T4258 |
13790-13797 |
JJ |
denotes |
anti-GR |
T4259 |
13798-13806 |
NN |
denotes |
antibody |
T4260 |
13807-13808 |
-LRB- |
denotes |
( |
T4261 |
13808-13813 |
NNP |
denotes |
Clone |
T4262 |
13814-13816 |
CD |
denotes |
41 |
T4263 |
13816-13817 |
-RRB- |
denotes |
) |
T4264 |
13818-13822 |
IN |
denotes |
from |
T4265 |
13823-13825 |
NNP |
denotes |
BD |
T4266 |
13826-13838 |
NNP |
denotes |
Transduction |
T4267 |
13839-13851 |
NNP |
denotes |
Laboratories |
T4268 |
13852-13853 |
-LRB- |
denotes |
( |
T4269 |
13853-13859 |
NNP |
denotes |
Oxford |
T4270 |
13859-13860 |
, |
denotes |
, |
T4271 |
13861-13863 |
NNP |
denotes |
UK |
T4272 |
13863-13864 |
-RRB- |
denotes |
) |
T4273 |
13865-13868 |
VBD |
denotes |
was |
T4274 |
13869-13873 |
VBN |
denotes |
used |
T4275 |
13874-13877 |
IN |
denotes |
for |
T4276 |
13878-13885 |
JJ |
denotes |
Western |
T4277 |
13886-13890 |
NN |
denotes |
blot |
T4278 |
13891-13899 |
NN |
denotes |
analysis |
T4279 |
13899-13900 |
. |
denotes |
. |
T4280 |
13901-13904 |
DT |
denotes |
All |
T4281 |
13905-13910 |
JJ |
denotes |
other |
T4282 |
13911-13919 |
NNS |
denotes |
reagents |
T4283 |
13920-13924 |
VBD |
denotes |
were |
T4284 |
13925-13934 |
VBN |
denotes |
purchased |
T4285 |
13935-13939 |
IN |
denotes |
from |
T4286 |
13940-13945 |
NNP |
denotes |
Sigma |
T4287 |
13946-13947 |
-LRB- |
denotes |
( |
T4288 |
13947-13952 |
NNP |
denotes |
Poole |
T4289 |
13952-13953 |
, |
denotes |
, |
T4290 |
13954-13956 |
NNP |
denotes |
UK |
T4291 |
13956-13957 |
-RRB- |
denotes |
) |
T4292 |
13957-13958 |
. |
denotes |
. |
T4470 |
13960-13964 |
NNP |
denotes |
Cell |
T4471 |
13965-13972 |
NNP |
denotes |
Culture |
T4472 |
13973-13976 |
CC |
denotes |
and |
T4473 |
13977-13981 |
NNP |
denotes |
PBMC |
T4474 |
13982-13991 |
NNP |
denotes |
Isolation |
T4475 |
13992-13993 |
NNP |
denotes |
A |
T4476 |
13994-13999 |
JJ |
denotes |
human |
T4477 |
14000-14001 |
NNP |
denotes |
T |
T4478 |
14002-14006 |
NN |
denotes |
cell |
T4479 |
14007-14011 |
NN |
denotes |
line |
T4480 |
14012-14013 |
-LRB- |
denotes |
( |
T4481 |
14013-14019 |
JJ |
denotes |
HuT-78 |
T4482 |
14019-14020 |
-RRB- |
denotes |
) |
T4483 |
14021-14024 |
VBD |
denotes |
was |
T4484 |
14025-14034 |
VBN |
denotes |
purchased |
T4485 |
14035-14039 |
IN |
denotes |
from |
T4486 |
14040-14045 |
NNP |
denotes |
ECACC |
T4487 |
14046-14054 |
NNP |
denotes |
European |
T4488 |
14055-14065 |
NNP |
denotes |
Collection |
T4489 |
14066-14068 |
IN |
denotes |
of |
T4490 |
14069-14073 |
NNP |
denotes |
Cell |
T4491 |
14074-14081 |
NNP |
denotes |
Culture |
T4492 |
14082-14083 |
-LRB- |
denotes |
( |
T4493 |
14083-14092 |
NNP |
denotes |
Wiltshire |
T4494 |
14092-14093 |
, |
denotes |
, |
T4495 |
14094-14096 |
NNP |
denotes |
UK |
T4496 |
14096-14097 |
-RRB- |
denotes |
) |
T4497 |
14098-14102 |
VBD |
denotes |
were |
T4498 |
14103-14111 |
VBN |
denotes |
cultured |
T4499 |
14112-14114 |
IN |
denotes |
as |
T4500 |
14115-14125 |
RB |
denotes |
previously |
T4501 |
14126-14135 |
VBN |
denotes |
described |
T4502 |
14136-14137 |
NNP |
denotes |
[ |
T4503 |
14137-14139 |
CD |
denotes |
12 |
T4504 |
14139-14140 |
NNP |
denotes |
] |
T4505 |
14140-14141 |
. |
denotes |
. |
T4506 |
14142-14147 |
NNS |
denotes |
PBMCs |
T4507 |
14148-14152 |
VBD |
denotes |
were |
T4508 |
14153-14161 |
VBN |
denotes |
isolated |
T4509 |
14162-14164 |
IN |
denotes |
by |
T4510 |
14165-14172 |
NN |
denotes |
density |
T4511 |
14173-14187 |
NN |
denotes |
centrifugation |
T4512 |
14188-14192 |
IN |
denotes |
over |
T4513 |
14193-14207 |
NNP |
denotes |
Ficoll-Hypaque |
T4514 |
14208-14209 |
-LRB- |
denotes |
( |
T4515 |
14209-14216 |
NN |
denotes |
density |
T4516 |
14216-14217 |
, |
denotes |
, |
T4517 |
14218-14223 |
CD |
denotes |
1.077 |
T4518 |
14224-14228 |
NN |
denotes |
g/ml |
T4519 |
14228-14229 |
: |
denotes |
; |
T4520 |
14230-14238 |
NNP |
denotes |
Amersham |
T4521 |
14239-14250 |
NNP |
denotes |
Biosciences |
T4522 |
14250-14251 |
, |
denotes |
, |
T4523 |
14252-14260 |
NNP |
denotes |
Amersham |
T4524 |
14260-14261 |
, |
denotes |
, |
T4525 |
14262-14264 |
NNP |
denotes |
UK |
T4526 |
14264-14265 |
-RRB- |
denotes |
) |
T4527 |
14266-14268 |
IN |
denotes |
as |
T4528 |
14269-14279 |
RB |
denotes |
previously |
T4529 |
14280-14289 |
VBN |
denotes |
described |
T4530 |
14290-14291 |
NNP |
denotes |
[ |
T4531 |
14291-14293 |
CD |
denotes |
34 |
T4532 |
14293-14294 |
NNP |
denotes |
] |
T4533 |
14294-14295 |
. |
denotes |
. |
T4534 |
14296-14301 |
NNS |
denotes |
Cells |
T4535 |
14302-14306 |
VBD |
denotes |
were |
T4536 |
14307-14317 |
VBN |
denotes |
stimulated |
T4537 |
14318-14322 |
IN |
denotes |
with |
T4538 |
14323-14331 |
JJ |
denotes |
anti-CD3 |
T4539 |
14331-14332 |
NN |
denotes |
/ |
T4540 |
14332-14336 |
NNP |
denotes |
CD28 |
T4541 |
14337-14338 |
-LRB- |
denotes |
( |
T4542 |
14338-14339 |
CD |
denotes |
1 |
T4543 |
14340-14342 |
NN |
denotes |
µg |
T4544 |
14342-14343 |
NN |
denotes |
/ |
T4545 |
14343-14345 |
NN |
denotes |
ml |
T4546 |
14346-14350 |
DT |
denotes |
each |
T4547 |
14350-14351 |
-RRB- |
denotes |
) |
T4548 |
14352-14355 |
IN |
denotes |
for |
T4549 |
14356-14357 |
CD |
denotes |
1 |
T4550 |
14358-14359 |
NN |
denotes |
h |
T4551 |
14360-14362 |
IN |
denotes |
at |
T4552 |
14363-14365 |
CD |
denotes |
37 |
T4553 |
14365-14366 |
CD |
denotes |
° |
T4554 |
14366-14367 |
NNP |
denotes |
C |
T4555 |
14368-14370 |
TO |
denotes |
to |
T4556 |
14371-14380 |
VB |
denotes |
stimulate |
T4557 |
14381-14384 |
JJ |
denotes |
Th2 |
T4558 |
14385-14393 |
NN |
denotes |
cytokine |
T4559 |
14394-14401 |
NN |
denotes |
release |
T4560 |
14402-14404 |
IN |
denotes |
in |
T4561 |
14405-14408 |
DT |
denotes |
the |
T4562 |
14409-14417 |
NN |
denotes |
presence |
T4563 |
14418-14420 |
CC |
denotes |
or |
T4564 |
14421-14428 |
NN |
denotes |
absence |
T4565 |
14429-14431 |
IN |
denotes |
of |
T4566 |
14432-14434 |
NNP |
denotes |
FP |
T4567 |
14435-14436 |
-LRB- |
denotes |
( |
T4568 |
14436-14438 |
CD |
denotes |
10 |
T4569 |
14438-14439 |
NN |
denotes |
− |
T4570 |
14439-14441 |
CD |
denotes |
12 |
T4571 |
14442-14444 |
TO |
denotes |
to |
T4572 |
14445-14447 |
CD |
denotes |
10 |
T4573 |
14447-14448 |
CD |
denotes |
− |
T4574 |
14448-14450 |
NNP |
denotes |
8M |
T4575 |
14450-14451 |
-RRB- |
denotes |
) |
T4576 |
14451-14452 |
. |
denotes |
. |
T4577 |
14453-14462 |
NNS |
denotes |
Cytospins |
T4578 |
14463-14467 |
VBD |
denotes |
were |
T4579 |
14468-14476 |
JJ |
denotes |
prepared |
T4580 |
14477-14480 |
CC |
denotes |
and |
T4581 |
14481-14487 |
JJ |
denotes |
GATA-3 |
T4582 |
14488-14500 |
NN |
denotes |
localization |
T4583 |
14501-14511 |
VBN |
denotes |
determined |
T4584 |
14512-14514 |
IN |
denotes |
by |
T4585 |
14515-14523 |
JJ |
denotes |
confocal |
T4586 |
14524-14534 |
NN |
denotes |
microscopy |
T4587 |
14535-14537 |
IN |
denotes |
as |
T4588 |
14538-14548 |
RB |
denotes |
previously |
T4589 |
14549-14558 |
VBN |
denotes |
described |
T4590 |
14559-14560 |
NNP |
denotes |
[ |
T4591 |
14560-14562 |
CD |
denotes |
12 |
T4592 |
14562-14563 |
NNP |
denotes |
] |
T4593 |
14563-14564 |
. |
denotes |
. |
T4717 |
14566-14573 |
VB |
denotes |
Reverse |
T4718 |
14574-14587 |
NNP |
denotes |
Transcription |
T4719 |
14588-14591 |
NNP |
denotes |
PCR |
T4720 |
14592-14597 |
NNP |
denotes |
Total |
T4721 |
14598-14601 |
NNP |
denotes |
RNA |
T4722 |
14602-14605 |
VBD |
denotes |
was |
T4723 |
14606-14615 |
VBN |
denotes |
extracted |
T4724 |
14616-14621 |
VBG |
denotes |
using |
T4725 |
14622-14627 |
NN |
denotes |
lysis |
T4726 |
14628-14634 |
NN |
denotes |
buffer |
T4727 |
14635-14636 |
-LRB- |
denotes |
( |
T4728 |
14636-14642 |
NNP |
denotes |
RNeasy |
T4729 |
14643-14646 |
NN |
denotes |
kit |
T4730 |
14646-14647 |
: |
denotes |
; |
T4731 |
14648-14654 |
NNP |
denotes |
Qiagen |
T4732 |
14654-14655 |
, |
denotes |
, |
T4733 |
14656-14663 |
NNP |
denotes |
Crawley |
T4734 |
14663-14664 |
, |
denotes |
, |
T4735 |
14665-14667 |
NNP |
denotes |
UK |
T4736 |
14667-14668 |
-RRB- |
denotes |
) |
T4737 |
14668-14669 |
. |
denotes |
. |
T4738 |
14670-14676 |
IN |
denotes |
During |
T4739 |
14677-14680 |
NNP |
denotes |
RNA |
T4740 |
14681-14693 |
NN |
denotes |
purification |
T4741 |
14693-14694 |
, |
denotes |
, |
T4742 |
14695-14702 |
JJ |
denotes |
genomic |
T4743 |
14703-14706 |
NN |
denotes |
DNA |
T4744 |
14707-14710 |
VBD |
denotes |
was |
T4745 |
14711-14719 |
VBN |
denotes |
digested |
T4746 |
14720-14724 |
IN |
denotes |
with |
T4747 |
14725-14735 |
JJ |
denotes |
RNase-free |
T4748 |
14736-14741 |
NNP |
denotes |
DNase |
T4749 |
14742-14743 |
-LRB- |
denotes |
( |
T4750 |
14743-14751 |
NNP |
denotes |
Amersham |
T4751 |
14752-14763 |
NNPS |
denotes |
Biosciences |
T4752 |
14763-14764 |
-RRB- |
denotes |
) |
T4753 |
14764-14765 |
. |
denotes |
. |
T4754 |
14766-14770 |
JJ |
denotes |
Next |
T4755 |
14770-14771 |
, |
denotes |
, |
T4756 |
14772-14775 |
CD |
denotes |
0.5 |
T4757 |
14776-14778 |
NN |
denotes |
µg |
T4758 |
14779-14781 |
IN |
denotes |
of |
T4759 |
14782-14787 |
JJ |
denotes |
total |
T4760 |
14788-14791 |
NNP |
denotes |
RNA |
T4761 |
14792-14795 |
VBD |
denotes |
was |
T4762 |
14796-14804 |
JJ |
denotes |
reversed |
T4763 |
14805-14816 |
VBN |
denotes |
transcribed |
T4764 |
14817-14822 |
VBG |
denotes |
using |
T4765 |
14823-14826 |
DT |
denotes |
the |
T4766 |
14827-14832 |
JJ |
denotes |
avian |
T4767 |
14833-14847 |
NN |
denotes |
myeloblastosis |
T4768 |
14848-14853 |
NN |
denotes |
virus |
T4769 |
14854-14856 |
NNP |
denotes |
RT |
T4770 |
14857-14858 |
-LRB- |
denotes |
( |
T4771 |
14858-14865 |
NNP |
denotes |
Promega |
T4772 |
14865-14866 |
, |
denotes |
, |
T4773 |
14867-14878 |
NNP |
denotes |
Southampton |
T4774 |
14878-14879 |
, |
denotes |
, |
T4775 |
14880-14882 |
NNP |
denotes |
UK |
T4776 |
14882-14883 |
-RRB- |
denotes |
) |
T4777 |
14883-14884 |
. |
denotes |
. |
T4778 |
14885-14888 |
IN |
denotes |
For |
T4779 |
14889-14897 |
JJ |
denotes |
relative |
T4780 |
14898-14912 |
NN |
denotes |
quantification |
T4781 |
14912-14913 |
, |
denotes |
, |
T4782 |
14914-14920 |
NN |
denotes |
RT-PCR |
T4783 |
14921-14924 |
VBD |
denotes |
was |
T4784 |
14925-14932 |
VBN |
denotes |
carried |
T4785 |
14933-14936 |
IN |
denotes |
out |
T4786 |
14937-14942 |
VBG |
denotes |
using |
T4787 |
14943-14947 |
NNP |
denotes |
cDNA |
T4788 |
14948-14954 |
NNS |
denotes |
probes |
T4789 |
14954-14955 |
. |
denotes |
. |
T4790 |
14956-14963 |
NNS |
denotes |
Primers |
T4791 |
14964-14967 |
IN |
denotes |
for |
T4792 |
14968-14972 |
NN |
denotes |
IL-4 |
T4793 |
14973-14977 |
VBD |
denotes |
were |
T4794 |
14978-14982 |
IN |
denotes |
from |
T4795 |
14983-14996 |
NNP |
denotes |
Sigma-Genosys |
T4796 |
14997-14998 |
-LRB- |
denotes |
( |
T4797 |
14998-15007 |
NNP |
denotes |
Cambridge |
T4798 |
15007-15008 |
, |
denotes |
, |
T4799 |
15009-15011 |
NNP |
denotes |
UK |
T4800 |
15011-15012 |
-RRB- |
denotes |
) |
T4801 |
15012-15013 |
. |
denotes |
. |
T4802 |
15014-15023 |
NNS |
denotes |
Sequences |
T4803 |
15024-15026 |
IN |
denotes |
of |
T4804 |
15027-15032 |
NNP |
denotes |
GADPH |
T4805 |
15033-15037 |
VBD |
denotes |
used |
T4806 |
15038-15041 |
VBP |
denotes |
are |
T4807 |
15042-15044 |
IN |
denotes |
as |
T4808 |
15045-15052 |
VBZ |
denotes |
follows |
T4809 |
15052-15053 |
: |
denotes |
: |
T4810 |
15054-15061 |
RB |
denotes |
forward |
T4811 |
15062-15063 |
CD |
denotes |
5 |
T4812 |
15063-15064 |
SYM |
denotes |
′ |
T4813 |
15064-15065 |
: |
denotes |
- |
T4814 |
15065-15088 |
NNP |
denotes |
CCACCCATGGCAAATTCCATGGC |
T4815 |
15088-15089 |
, |
denotes |
, |
T4816 |
15090-15097 |
VB |
denotes |
reverse |
T4817 |
15098-15099 |
CD |
denotes |
3 |
T4818 |
15099-15100 |
SYM |
denotes |
′ |
T4819 |
15100-15101 |
: |
denotes |
- |
T4820 |
15101-15124 |
NNP |
denotes |
TCTAGACGGCAGGTCAGGTCCAC |
T4821 |
15124-15125 |
. |
denotes |
. |
T5013 |
15127-15131 |
NNP |
denotes |
Cell |
T5014 |
15132-15145 |
NNP |
denotes |
Fractionation |
T5015 |
15145-15146 |
, |
denotes |
, |
T5016 |
15147-15166 |
NNP |
denotes |
Immunoprecipitation |
T5017 |
15166-15167 |
, |
denotes |
, |
T5018 |
15168-15171 |
CC |
denotes |
and |
T5019 |
15172-15179 |
JJ |
denotes |
Western |
T5020 |
15180-15184 |
NNP |
denotes |
Blot |
T5021 |
15185-15193 |
NNP |
denotes |
Analysis |
T5022 |
15194-15201 |
NNP |
denotes |
Nuclear |
T5023 |
15202-15205 |
CC |
denotes |
and |
T5024 |
15206-15217 |
JJ |
denotes |
cytoplasmic |
T5025 |
15218-15227 |
NNS |
denotes |
fractions |
T5026 |
15228-15232 |
VBD |
denotes |
were |
T5027 |
15233-15241 |
VBN |
denotes |
prepared |
T5028 |
15242-15244 |
IN |
denotes |
as |
T5029 |
15245-15255 |
RB |
denotes |
previously |
T5030 |
15256-15265 |
VBN |
denotes |
described |
T5031 |
15266-15267 |
NNP |
denotes |
[ |
T5032 |
15267-15269 |
CD |
denotes |
35 |
T5033 |
15269-15270 |
NNP |
denotes |
] |
T5034 |
15270-15271 |
. |
denotes |
. |
T5035 |
15272-15277 |
JJ |
denotes |
Whole |
T5036 |
15278-15282 |
NN |
denotes |
cell |
T5037 |
15283-15290 |
NNS |
denotes |
lysates |
T5038 |
15291-15295 |
VBD |
denotes |
were |
T5039 |
15296-15304 |
VBN |
denotes |
prepared |
T5040 |
15305-15307 |
IN |
denotes |
in |
T5041 |
15308-15313 |
NN |
denotes |
NP-40 |
T5042 |
15314-15319 |
NN |
denotes |
lysis |
T5043 |
15320-15326 |
NN |
denotes |
buffer |
T5044 |
15327-15328 |
-LRB- |
denotes |
( |
T5045 |
15328-15331 |
CD |
denotes |
0.5 |
T5046 |
15331-15332 |
NN |
denotes |
% |
T5047 |
15333-15340 |
NNP |
denotes |
Nonidet |
T5048 |
15341-15345 |
NNP |
denotes |
P-40 |
T5049 |
15345-15346 |
, |
denotes |
, |
T5050 |
15347-15349 |
CD |
denotes |
20 |
T5051 |
15350-15352 |
NNP |
denotes |
mM |
T5052 |
15353-15361 |
NNP |
denotes |
Tris-HCl |
T5053 |
15362-15363 |
NNP |
denotes |
[ |
T5054 |
15363-15365 |
NNP |
denotes |
pH |
T5055 |
15366-15369 |
CD |
denotes |
7.5 |
T5056 |
15369-15370 |
NNP |
denotes |
] |
T5057 |
15370-15371 |
, |
denotes |
, |
T5058 |
15372-15375 |
CD |
denotes |
150 |
T5059 |
15376-15378 |
NNP |
denotes |
mM |
T5060 |
15379-15383 |
NNP |
denotes |
NaCl |
T5061 |
15383-15384 |
-RRB- |
denotes |
) |
T5062 |
15385-15387 |
IN |
denotes |
in |
T5063 |
15388-15391 |
DT |
denotes |
the |
T5064 |
15392-15400 |
NN |
denotes |
presence |
T5065 |
15401-15403 |
IN |
denotes |
of |
T5066 |
15404-15412 |
JJ |
denotes |
complete |
T5067 |
15413-15421 |
NN |
denotes |
protease |
T5068 |
15422-15430 |
NN |
denotes |
cocktail |
T5069 |
15431-15440 |
NN |
denotes |
inhibitor |
T5070 |
15440-15441 |
. |
denotes |
. |
T5071 |
15442-15449 |
NNS |
denotes |
Lysates |
T5072 |
15450-15454 |
VBD |
denotes |
were |
T5073 |
15455-15466 |
VBN |
denotes |
centrifuged |
T5074 |
15467-15469 |
IN |
denotes |
at |
T5075 |
15470-15471 |
CD |
denotes |
4 |
T5076 |
15471-15472 |
CD |
denotes |
° |
T5077 |
15472-15473 |
NNP |
denotes |
C |
T5078 |
15474-15477 |
IN |
denotes |
for |
T5079 |
15478-15480 |
CD |
denotes |
10 |
T5080 |
15481-15484 |
NN |
denotes |
min |
T5081 |
15485-15487 |
IN |
denotes |
at |
T5082 |
15488-15494 |
CD |
denotes |
12,000 |
T5083 |
15495-15498 |
NN |
denotes |
rpm |
T5084 |
15499-15501 |
IN |
denotes |
in |
T5085 |
15502-15504 |
DT |
denotes |
an |
T5086 |
15505-15514 |
NNP |
denotes |
Eppendorf |
T5087 |
15515-15530 |
NN |
denotes |
microcentrifuge |
T5088 |
15531-15533 |
TO |
denotes |
to |
T5089 |
15534-15540 |
VB |
denotes |
remove |
T5090 |
15541-15549 |
JJ |
denotes |
cellular |
T5091 |
15550-15556 |
NN |
denotes |
debris |
T5092 |
15556-15557 |
. |
denotes |
. |
T5093 |
15558-15565 |
NNS |
denotes |
Samples |
T5094 |
15566-15570 |
VBD |
denotes |
were |
T5095 |
15571-15575 |
RB |
denotes |
then |
T5096 |
15576-15594 |
VBN |
denotes |
immunoprecipitated |
T5097 |
15595-15599 |
IN |
denotes |
with |
T5098 |
15600-15606 |
DT |
denotes |
either |
T5099 |
15607-15609 |
CD |
denotes |
10 |
T5100 |
15610-15612 |
NN |
denotes |
µl |
T5101 |
15613-15615 |
IN |
denotes |
of |
T5102 |
15616-15624 |
NN |
denotes |
antibody |
T5103 |
15625-15632 |
IN |
denotes |
against |
T5104 |
15633-15639 |
NNP |
denotes |
GATA-3 |
T5105 |
15640-15642 |
CC |
denotes |
or |
T5106 |
15643-15653 |
JJ |
denotes |
importin-α |
T5107 |
15654-15659 |
VBG |
denotes |
using |
T5108 |
15660-15663 |
NNP |
denotes |
A/G |
T5109 |
15664-15671 |
JJ |
denotes |
agarose |
T5110 |
15672-15678 |
NN |
denotes |
slurry |
T5111 |
15679-15681 |
IN |
denotes |
in |
T5112 |
15682-15685 |
DT |
denotes |
the |
T5113 |
15686-15694 |
NN |
denotes |
presence |
T5114 |
15695-15697 |
IN |
denotes |
of |
T5115 |
15698-15706 |
NN |
denotes |
protease |
T5116 |
15707-15716 |
NN |
denotes |
inhibitor |
T5117 |
15717-15722 |
VBG |
denotes |
using |
T5118 |
15723-15726 |
DT |
denotes |
the |
T5119 |
15727-15732 |
NNP |
denotes |
Catch |
T5120 |
15733-15736 |
CC |
denotes |
and |
T5121 |
15737-15744 |
NNP |
denotes |
Release |
T5122 |
15745-15756 |
NN |
denotes |
methodology |
T5123 |
15757-15758 |
-LRB- |
denotes |
( |
T5124 |
15758-15765 |
NNP |
denotes |
Upstate |
T5125 |
15766-15779 |
NNP |
denotes |
Biotechnology |
T5126 |
15779-15780 |
, |
denotes |
, |
T5127 |
15781-15785 |
NNP |
denotes |
Lake |
T5128 |
15786-15792 |
NNP |
denotes |
Placid |
T5129 |
15792-15793 |
, |
denotes |
, |
T5130 |
15794-15797 |
NNP |
denotes |
New |
T5131 |
15798-15802 |
NNP |
denotes |
York |
T5132 |
15802-15803 |
, |
denotes |
, |
T5133 |
15804-15807 |
NNP |
denotes |
USA |
T5134 |
15807-15808 |
-RRB- |
denotes |
) |
T5135 |
15808-15809 |
. |
denotes |
. |
T5136 |
15810-15817 |
JJ |
denotes |
Western |
T5137 |
15818-15822 |
NN |
denotes |
blot |
T5138 |
15823-15831 |
NN |
denotes |
analysis |
T5139 |
15832-15835 |
VBD |
denotes |
was |
T5140 |
15836-15845 |
VBN |
denotes |
performed |
T5141 |
15846-15851 |
VBG |
denotes |
using |
T5142 |
15852-15863 |
JJ |
denotes |
anti-GATA-3 |
T5143 |
15863-15864 |
, |
denotes |
, |
T5144 |
15865-15880 |
JJ |
denotes |
anti-importin-α |
T5145 |
15880-15881 |
, |
denotes |
, |
T5146 |
15882-15889 |
JJ |
denotes |
anti-GR |
T5147 |
15889-15890 |
, |
denotes |
, |
T5148 |
15891-15901 |
JJ |
denotes |
anti-p-p38 |
T5149 |
15902-15905 |
NNP |
denotes |
MAP |
T5150 |
15906-15912 |
NN |
denotes |
kinase |
T5151 |
15912-15913 |
, |
denotes |
, |
T5152 |
15914-15926 |
JJ |
denotes |
anti-p-ATF-2 |
T5153 |
15926-15927 |
, |
denotes |
, |
T5154 |
15928-15931 |
CC |
denotes |
and |
T5155 |
15932-15945 |
JJ |
denotes |
anti-p-serine |
T5156 |
15945-15946 |
. |
denotes |
. |
T5157 |
15947-15961 |
JJ |
denotes |
Immunoreactive |
T5158 |
15962-15970 |
NNS |
denotes |
proteins |
T5159 |
15971-15975 |
VBD |
denotes |
were |
T5160 |
15976-15984 |
VBN |
denotes |
detected |
T5161 |
15985-15990 |
VBG |
denotes |
using |
T5162 |
15991-15993 |
DT |
denotes |
an |
T5163 |
15994-16002 |
JJ |
denotes |
enhanced |
T5164 |
16003-16020 |
NN |
denotes |
chemiluminescence |
T5165 |
16021-16024 |
NNP |
denotes |
ECL |
T5166 |
16025-16028 |
NN |
denotes |
kit |
T5167 |
16029-16030 |
-LRB- |
denotes |
( |
T5168 |
16030-16038 |
NNP |
denotes |
Amersham |
T5169 |
16039-16050 |
NNPS |
denotes |
Biosciences |
T5170 |
16050-16051 |
-RRB- |
denotes |
) |
T5171 |
16051-16052 |
. |
denotes |
. |
T5318 |
16054-16063 |
NNP |
denotes |
Chromatin |
T5319 |
16064-16083 |
NNP |
denotes |
Immunoprecipitation |
T5320 |
16084-16093 |
NNP |
denotes |
Chromatin |
T5321 |
16094-16113 |
NN |
denotes |
immunoprecipitation |
T5322 |
16114-16115 |
-LRB- |
denotes |
( |
T5323 |
16115-16117 |
NNP |
denotes |
IP |
T5324 |
16117-16118 |
-RRB- |
denotes |
) |
T5325 |
16119-16122 |
VBD |
denotes |
was |
T5326 |
16123-16132 |
VBN |
denotes |
performed |
T5327 |
16133-16135 |
IN |
denotes |
as |
T5328 |
16136-16146 |
RB |
denotes |
previously |
T5329 |
16147-16156 |
VBN |
denotes |
described |
T5330 |
16157-16158 |
NNP |
denotes |
[ |
T5331 |
16158-16160 |
CD |
denotes |
12 |
T5332 |
16160-16161 |
NNP |
denotes |
] |
T5333 |
16162-16164 |
IN |
denotes |
in |
T5334 |
16165-16171 |
NNP |
denotes |
HuT-78 |
T5335 |
16172-16179 |
NNS |
denotes |
T-cells |
T5336 |
16180-16184 |
IN |
denotes |
with |
T5337 |
16185-16186 |
CD |
denotes |
2 |
T5338 |
16187-16189 |
NN |
denotes |
µg |
T5339 |
16190-16192 |
IN |
denotes |
of |
T5340 |
16193-16204 |
JJ |
denotes |
anti-GATA-3 |
T5341 |
16205-16206 |
-LRB- |
denotes |
( |
T5342 |
16206-16211 |
NNP |
denotes |
Santa |
T5343 |
16212-16216 |
NNP |
denotes |
Cruz |
T5344 |
16217-16230 |
NNP |
denotes |
Biotechnology |
T5345 |
16230-16231 |
-RRB- |
denotes |
) |
T5346 |
16231-16232 |
, |
denotes |
, |
T5347 |
16233-16235 |
CC |
denotes |
or |
T5348 |
16236-16244 |
JJ |
denotes |
isotypic |
T5349 |
16245-16259 |
NN |
denotes |
immunoglobulin |
T5350 |
16260-16261 |
NNP |
denotes |
G |
T5351 |
16262-16264 |
IN |
denotes |
as |
T5352 |
16265-16266 |
DT |
denotes |
a |
T5353 |
16267-16279 |
JJ |
denotes |
non-specific |
T5354 |
16280-16287 |
NN |
denotes |
control |
T5355 |
16288-16289 |
-LRB- |
denotes |
( |
T5356 |
16289-16294 |
NNP |
denotes |
Santa |
T5357 |
16295-16299 |
NNP |
denotes |
Cruz |
T5358 |
16300-16313 |
NNP |
denotes |
Biotechnology |
T5359 |
16313-16314 |
-RRB- |
denotes |
) |
T5360 |
16315-16324 |
RB |
denotes |
overnight |
T5361 |
16325-16327 |
IN |
denotes |
at |
T5362 |
16328-16329 |
CD |
denotes |
4 |
T5363 |
16329-16330 |
CD |
denotes |
° |
T5364 |
16330-16332 |
NNP |
denotes |
C. |
T5365 |
16333-16341 |
NNP |
denotes |
Promoter |
T5366 |
16342-16351 |
NNS |
denotes |
sequences |
T5367 |
16352-16356 |
VBD |
denotes |
were |
T5368 |
16357-16365 |
VBN |
denotes |
detected |
T5369 |
16366-16370 |
IN |
denotes |
with |
T5370 |
16371-16374 |
NNP |
denotes |
PCR |
T5371 |
16375-16382 |
NNS |
denotes |
primers |
T5372 |
16383-16386 |
IN |
denotes |
for |
T5373 |
16387-16390 |
DT |
denotes |
the |
T5374 |
16391-16395 |
NN |
denotes |
IL-5 |
T5375 |
16396-16404 |
NN |
denotes |
promoter |
T5376 |
16405-16406 |
-LRB- |
denotes |
( |
T5377 |
16406-16407 |
FW |
denotes |
− |
T5378 |
16407-16410 |
CD |
denotes |
445 |
T5379 |
16411-16413 |
TO |
denotes |
to |
T5380 |
16414-16416 |
CD |
denotes |
+4 |
T5381 |
16416-16417 |
-RRB- |
denotes |
) |
T5382 |
16417-16418 |
: |
denotes |
: |
T5383 |
16419-16426 |
RB |
denotes |
forward |
T5384 |
16427-16428 |
CD |
denotes |
5 |
T5385 |
16428-16429 |
SYM |
denotes |
′ |
T5386 |
16429-16430 |
: |
denotes |
- |
T5387 |
16430-16453 |
NN |
denotes |
TTAATCTAGCCACAGTCATAG-3 |
T5388 |
16453-16454 |
NN |
denotes |
′ |
T5389 |
16455-16458 |
CC |
denotes |
and |
T5390 |
16459-16466 |
NN |
denotes |
reverse |
T5391 |
16466-16467 |
: |
denotes |
: |
T5392 |
16468-16469 |
CD |
denotes |
5 |
T5393 |
16469-16470 |
SYM |
denotes |
′ |
T5394 |
16470-16471 |
: |
denotes |
- |
T5395 |
16471-16494 |
NN |
denotes |
TCATGGCTCTGAAACGTTCTG-3 |
T5396 |
16494-16495 |
NN |
denotes |
′ |
T5397 |
16495-16496 |
. |
denotes |
. |
T5398 |
16497-16500 |
NNP |
denotes |
PCR |
T5399 |
16501-16504 |
VBD |
denotes |
was |
T5400 |
16505-16514 |
VBN |
denotes |
performed |
T5401 |
16515-16520 |
VBG |
denotes |
using |
T5402 |
16521-16522 |
DT |
denotes |
a |
T5403 |
16523-16529 |
NNP |
denotes |
Hybaid |
T5404 |
16530-16538 |
NNP |
denotes |
Omnigene |
T5405 |
16539-16546 |
JJ |
denotes |
thermal |
T5406 |
16547-16553 |
NN |
denotes |
cycler |
T5407 |
16554-16555 |
-LRB- |
denotes |
( |
T5408 |
16555-16561 |
NNP |
denotes |
Hybaid |
T5409 |
16561-16562 |
, |
denotes |
, |
T5410 |
16563-16570 |
NNP |
denotes |
Ashford |
T5411 |
16570-16571 |
, |
denotes |
, |
T5412 |
16572-16574 |
NNP |
denotes |
UK |
T5413 |
16574-16575 |
-RRB- |
denotes |
) |
T5414 |
16576-16580 |
IN |
denotes |
with |
T5415 |
16581-16588 |
NN |
denotes |
cycling |
T5416 |
16589-16599 |
NNS |
denotes |
parameters |
T5417 |
16600-16602 |
IN |
denotes |
of |
T5418 |
16603-16605 |
CD |
denotes |
72 |
T5419 |
16605-16606 |
CD |
denotes |
° |
T5420 |
16606-16607 |
NNP |
denotes |
C |
T5421 |
16608-16611 |
IN |
denotes |
for |
T5422 |
16612-16614 |
CD |
denotes |
10 |
T5423 |
16615-16618 |
NN |
denotes |
min |
T5424 |
16618-16619 |
, |
denotes |
, |
T5425 |
16620-16622 |
CD |
denotes |
35 |
T5426 |
16623-16629 |
NNS |
denotes |
cycles |
T5427 |
16630-16632 |
IN |
denotes |
at |
T5428 |
16633-16635 |
CD |
denotes |
94 |
T5429 |
16635-16636 |
CD |
denotes |
° |
T5430 |
16636-16637 |
NNP |
denotes |
C |
T5431 |
16638-16641 |
IN |
denotes |
for |
T5432 |
16642-16644 |
CD |
denotes |
45 |
T5433 |
16645-16646 |
PRP |
denotes |
s |
T5434 |
16646-16647 |
, |
denotes |
, |
T5435 |
16648-16650 |
CD |
denotes |
52 |
T5436 |
16650-16651 |
NN |
denotes |
° |
T5437 |
16651-16652 |
NNP |
denotes |
C |
T5438 |
16653-16656 |
IN |
denotes |
for |
T5439 |
16657-16659 |
CD |
denotes |
45 |
T5440 |
16660-16661 |
PRP |
denotes |
s |
T5441 |
16661-16662 |
, |
denotes |
, |
T5442 |
16663-16665 |
CD |
denotes |
72 |
T5443 |
16665-16666 |
NN |
denotes |
° |
T5444 |
16666-16667 |
NNP |
denotes |
C |
T5445 |
16668-16671 |
IN |
denotes |
for |
T5446 |
16672-16674 |
CD |
denotes |
45 |
T5447 |
16675-16677 |
NN |
denotes |
s. |
T5754 |
16679-16688 |
CD |
denotes |
GR-GATA-3 |
T5755 |
16689-16691 |
IN |
denotes |
In |
T5756 |
16692-16697 |
NNP |
denotes |
Vitro |
T5757 |
16698-16709 |
NNP |
denotes |
Competition |
T5758 |
16710-16715 |
NNP |
denotes |
Assay |
T5759 |
16716-16719 |
IN |
denotes |
for |
T5760 |
16720-16730 |
NNP |
denotes |
Importin-α |
T5761 |
16731-16732 |
-LRB- |
denotes |
( |
T5762 |
16732-16743 |
NNP |
denotes |
Far-Western |
T5763 |
16744-16749 |
NNP |
denotes |
ELISA |
T5764 |
16749-16750 |
-RRB- |
denotes |
) |
T5765 |
16751-16769 |
NNP |
denotes |
Immunoprecipitated |
T5766 |
16770-16780 |
NN |
denotes |
importin-α |
T5767 |
16781-16782 |
-LRB- |
denotes |
( |
T5768 |
16782-16797 |
JJ |
denotes |
anti-importin-α |
T5769 |
16797-16798 |
, |
denotes |
, |
T5770 |
16799-16804 |
NNP |
denotes |
Santa |
T5771 |
16805-16809 |
NNP |
denotes |
Cruz |
T5772 |
16810-16823 |
NNP |
denotes |
Biotechnology |
T5773 |
16823-16824 |
-RRB- |
denotes |
) |
T5774 |
16825-16829 |
IN |
denotes |
from |
T5775 |
16830-16836 |
JJ |
denotes |
HuT-78 |
T5776 |
16837-16842 |
NNS |
denotes |
cells |
T5777 |
16843-16846 |
VBD |
denotes |
was |
T5778 |
16847-16856 |
VBN |
denotes |
separated |
T5779 |
16857-16859 |
IN |
denotes |
by |
T5780 |
16860-16868 |
NNP |
denotes |
SDS-PAGE |
T5781 |
16869-16872 |
CC |
denotes |
and |
T5782 |
16873-16881 |
VBN |
denotes |
purified |
T5783 |
16882-16886 |
IN |
denotes |
from |
T5784 |
16887-16890 |
DT |
denotes |
the |
T5785 |
16891-16898 |
VBN |
denotes |
excised |
T5786 |
16899-16902 |
NN |
denotes |
gel |
T5787 |
16903-16905 |
IN |
denotes |
by |
T5788 |
16906-16920 |
NN |
denotes |
electroelution |
T5789 |
16921-16922 |
NNP |
denotes |
[ |
T5790 |
16922-16924 |
CD |
denotes |
36 |
T5791 |
16924-16925 |
NNP |
denotes |
] |
T5792 |
16925-16926 |
. |
denotes |
. |
T5793 |
16927-16936 |
RB |
denotes |
Similarly |
T5794 |
16936-16937 |
, |
denotes |
, |
T5795 |
16938-16944 |
NN |
denotes |
GATA-3 |
T5796 |
16945-16948 |
VBD |
denotes |
was |
T5797 |
16949-16957 |
VBN |
denotes |
isolated |
T5798 |
16958-16962 |
IN |
denotes |
from |
T5799 |
16963-16976 |
JJ |
denotes |
nonstimulated |
T5800 |
16977-16983 |
JJ |
denotes |
HuT-78 |
T5801 |
16984-16989 |
NNS |
denotes |
cells |
T5802 |
16990-16992 |
CC |
denotes |
or |
T5803 |
16993-16998 |
NNS |
denotes |
cells |
T5804 |
16999-17009 |
VBD |
denotes |
stimulated |
T5805 |
17010-17013 |
IN |
denotes |
for |
T5806 |
17014-17016 |
CD |
denotes |
30 |
T5807 |
17017-17020 |
NN |
denotes |
min |
T5808 |
17021-17025 |
IN |
denotes |
with |
T5809 |
17026-17034 |
JJ |
denotes |
anti-CD3 |
T5810 |
17034-17035 |
NN |
denotes |
/ |
T5811 |
17035-17039 |
CD |
denotes |
CD28 |
T5812 |
17040-17043 |
CC |
denotes |
and |
T5813 |
17044-17046 |
NNP |
denotes |
GR |
T5814 |
17047-17050 |
VBD |
denotes |
was |
T5815 |
17051-17059 |
VBN |
denotes |
isolated |
T5816 |
17060-17064 |
IN |
denotes |
from |
T5817 |
17065-17067 |
NNP |
denotes |
FP |
T5818 |
17068-17069 |
-LRB- |
denotes |
( |
T5819 |
17069-17071 |
CD |
denotes |
10 |
T5820 |
17071-17072 |
NN |
denotes |
− |
T5821 |
17072-17073 |
CD |
denotes |
8 |
T5822 |
17074-17075 |
NNP |
denotes |
M |
T5823 |
17075-17076 |
, |
denotes |
, |
T5824 |
17077-17079 |
CD |
denotes |
30 |
T5825 |
17080-17083 |
NN |
denotes |
min |
T5826 |
17083-17084 |
-RRB- |
denotes |
) |
T5827 |
17085-17095 |
VBD |
denotes |
stimulated |
T5828 |
17096-17102 |
JJ |
denotes |
HuT-78 |
T5829 |
17103-17108 |
NNS |
denotes |
cells |
T5830 |
17108-17109 |
. |
denotes |
. |
T5831 |
17110-17115 |
DT |
denotes |
These |
T5832 |
17116-17124 |
NNS |
denotes |
proteins |
T5833 |
17125-17129 |
VBD |
denotes |
were |
T5834 |
17130-17142 |
RB |
denotes |
subsequently |
T5835 |
17143-17151 |
VBN |
denotes |
refolded |
T5836 |
17152-17154 |
IN |
denotes |
in |
T5837 |
17155-17162 |
NN |
denotes |
glycine |
T5838 |
17163-17171 |
NN |
denotes |
solution |
T5839 |
17171-17172 |
. |
denotes |
. |
T5840 |
17173-17176 |
CD |
denotes |
100 |
T5841 |
17177-17179 |
NN |
denotes |
µl |
T5842 |
17180-17182 |
IN |
denotes |
of |
T5843 |
17183-17193 |
JJ |
denotes |
importin-α |
T5844 |
17194-17202 |
NN |
denotes |
solution |
T5845 |
17203-17204 |
-LRB- |
denotes |
( |
T5846 |
17204-17207 |
CD |
denotes |
100 |
T5847 |
17208-17213 |
NN |
denotes |
ng/ml |
T5848 |
17214-17216 |
IN |
denotes |
in |
T5849 |
17217-17220 |
NNP |
denotes |
TBS |
T5850 |
17220-17221 |
-RRB- |
denotes |
) |
T5851 |
17222-17225 |
VBD |
denotes |
was |
T5852 |
17226-17231 |
VBN |
denotes |
added |
T5853 |
17232-17234 |
TO |
denotes |
to |
T5854 |
17235-17242 |
JJ |
denotes |
96-well |
T5855 |
17243-17249 |
NNS |
denotes |
plates |
T5856 |
17250-17256 |
VBN |
denotes |
coated |
T5857 |
17257-17261 |
IN |
denotes |
with |
T5858 |
17262-17266 |
NN |
denotes |
goat |
T5859 |
17267-17282 |
JJ |
denotes |
anti-importin-α |
T5860 |
17283-17291 |
NN |
denotes |
antibody |
T5861 |
17291-17292 |
. |
denotes |
. |
T5862 |
17293-17298 |
IN |
denotes |
After |
T5863 |
17299-17300 |
CD |
denotes |
1 |
T5864 |
17301-17302 |
NN |
denotes |
h |
T5865 |
17303-17313 |
NN |
denotes |
incubation |
T5866 |
17313-17314 |
, |
denotes |
, |
T5867 |
17315-17321 |
NNP |
denotes |
GATA-3 |
T5868 |
17322-17323 |
-LRB- |
denotes |
( |
T5869 |
17323-17326 |
CD |
denotes |
100 |
T5870 |
17327-17332 |
NN |
denotes |
ng/ml |
T5871 |
17333-17335 |
IN |
denotes |
in |
T5872 |
17336-17339 |
NNP |
denotes |
TBS |
T5873 |
17339-17340 |
-RRB- |
denotes |
) |
T5874 |
17341-17345 |
IN |
denotes |
from |
T5875 |
17346-17356 |
VBN |
denotes |
stimulated |
T5876 |
17357-17359 |
CC |
denotes |
or |
T5877 |
17360-17372 |
JJ |
denotes |
unstimulated |
T5878 |
17373-17378 |
NNS |
denotes |
cells |
T5879 |
17379-17383 |
VBD |
denotes |
were |
T5880 |
17384-17389 |
VBN |
denotes |
added |
T5881 |
17390-17392 |
TO |
denotes |
to |
T5882 |
17393-17396 |
DT |
denotes |
the |
T5883 |
17397-17414 |
JJ |
denotes |
importin-α-coated |
T5884 |
17415-17420 |
NNS |
denotes |
wells |
T5885 |
17420-17421 |
. |
denotes |
. |
T5886 |
17422-17424 |
NNP |
denotes |
GR |
T5887 |
17425-17426 |
-LRB- |
denotes |
( |
T5888 |
17426-17428 |
CD |
denotes |
10 |
T5889 |
17429-17431 |
CC |
denotes |
or |
T5890 |
17432-17435 |
CD |
denotes |
100 |
T5891 |
17436-17441 |
NN |
denotes |
ng/ml |
T5892 |
17442-17444 |
IN |
denotes |
in |
T5893 |
17445-17448 |
NNP |
denotes |
TBS |
T5894 |
17448-17449 |
-RRB- |
denotes |
) |
T5895 |
17450-17454 |
IN |
denotes |
from |
T5896 |
17455-17465 |
VBN |
denotes |
stimulated |
T5897 |
17466-17468 |
CC |
denotes |
or |
T5898 |
17469-17481 |
JJ |
denotes |
unstimulated |
T5899 |
17482-17487 |
NNS |
denotes |
cells |
T5900 |
17488-17492 |
VBD |
denotes |
were |
T5901 |
17493-17498 |
VBN |
denotes |
added |
T5902 |
17499-17501 |
TO |
denotes |
to |
T5903 |
17502-17506 |
DT |
denotes |
some |
T5904 |
17507-17512 |
NNS |
denotes |
wells |
T5905 |
17512-17513 |
. |
denotes |
. |
T5906 |
17514-17519 |
IN |
denotes |
After |
T5907 |
17520-17521 |
DT |
denotes |
a |
T5908 |
17522-17529 |
JJ |
denotes |
further |
T5909 |
17530-17531 |
CD |
denotes |
1 |
T5910 |
17532-17533 |
NN |
denotes |
h |
T5911 |
17534-17544 |
NN |
denotes |
incubation |
T5912 |
17544-17545 |
, |
denotes |
, |
T5913 |
17546-17549 |
DT |
denotes |
the |
T5914 |
17550-17555 |
NN |
denotes |
plate |
T5915 |
17556-17559 |
VBD |
denotes |
was |
T5916 |
17560-17566 |
VBN |
denotes |
washed |
T5917 |
17567-17570 |
CC |
denotes |
and |
T5918 |
17571-17580 |
VBN |
denotes |
incubated |
T5919 |
17581-17585 |
IN |
denotes |
with |
T5920 |
17586-17593 |
JJ |
denotes |
primary |
T5921 |
17594-17604 |
NNS |
denotes |
antibodies |
T5922 |
17605-17606 |
-LRB- |
denotes |
( |
T5923 |
17606-17607 |
DT |
denotes |
a |
T5924 |
17608-17615 |
NN |
denotes |
mixture |
T5925 |
17616-17618 |
IN |
denotes |
of |
T5926 |
17619-17625 |
NN |
denotes |
rabbit |
T5927 |
17626-17637 |
JJ |
denotes |
anti-GATA-3 |
T5928 |
17638-17641 |
CC |
denotes |
and |
T5929 |
17642-17647 |
NN |
denotes |
mouse |
T5930 |
17648-17655 |
JJ |
denotes |
anti-GR |
T5931 |
17655-17656 |
, |
denotes |
, |
T5932 |
17657-17662 |
NNP |
denotes |
Santa |
T5933 |
17663-17667 |
NNP |
denotes |
Cruz |
T5934 |
17668-17681 |
NNP |
denotes |
Biotechnology |
T5935 |
17681-17682 |
-RRB- |
denotes |
) |
T5936 |
17683-17686 |
IN |
denotes |
for |
T5937 |
17687-17690 |
CD |
denotes |
1.5 |
T5938 |
17691-17692 |
NN |
denotes |
h |
T5939 |
17692-17693 |
, |
denotes |
, |
T5940 |
17694-17697 |
CC |
denotes |
and |
T5941 |
17698-17702 |
RB |
denotes |
then |
T5942 |
17703-17712 |
VBN |
denotes |
incubated |
T5943 |
17713-17717 |
IN |
denotes |
with |
T5944 |
17718-17727 |
JJ |
denotes |
secondary |
T5945 |
17728-17738 |
NNS |
denotes |
antibodies |
T5946 |
17738-17739 |
. |
denotes |
. |
T5947 |
17740-17744 |
CD |
denotes |
FITC |
T5948 |
17745-17750 |
NNS |
denotes |
swine |
T5949 |
17751-17762 |
JJ |
denotes |
anti-rabbit |
T5950 |
17763-17766 |
NNP |
denotes |
IgG |
T5951 |
17767-17768 |
-LRB- |
denotes |
( |
T5952 |
17768-17772 |
NNP |
denotes |
Dako |
T5953 |
17772-17773 |
, |
denotes |
, |
T5954 |
17774-17783 |
NNP |
denotes |
Cambridge |
T5955 |
17783-17784 |
, |
denotes |
, |
T5956 |
17785-17787 |
NNP |
denotes |
UK |
T5957 |
17787-17788 |
-RRB- |
denotes |
) |
T5958 |
17789-17792 |
VBD |
denotes |
was |
T5959 |
17793-17797 |
VBN |
denotes |
used |
T5960 |
17798-17801 |
IN |
denotes |
for |
T5961 |
17802-17805 |
DT |
denotes |
the |
T5962 |
17806-17815 |
NN |
denotes |
detection |
T5963 |
17816-17818 |
IN |
denotes |
of |
T5964 |
17819-17825 |
NNP |
denotes |
GATA-3 |
T5965 |
17825-17826 |
, |
denotes |
, |
T5966 |
17827-17830 |
CC |
denotes |
and |
T5967 |
17831-17840 |
JJ |
denotes |
rhodamine |
T5968 |
17841-17847 |
NN |
denotes |
donkey |
T5969 |
17848-17858 |
JJ |
denotes |
anti-mouse |
T5970 |
17859-17862 |
NNP |
denotes |
IgG |
T5971 |
17863-17864 |
-LRB- |
denotes |
( |
T5972 |
17864-17869 |
NNP |
denotes |
Novus |
T5973 |
17869-17870 |
, |
denotes |
, |
T5974 |
17871-17880 |
NNP |
denotes |
Littleton |
T5975 |
17880-17881 |
, |
denotes |
, |
T5976 |
17882-17890 |
NNP |
denotes |
Colorado |
T5977 |
17890-17891 |
, |
denotes |
, |
T5978 |
17892-17895 |
NNP |
denotes |
USA |
T5979 |
17895-17896 |
-RRB- |
denotes |
) |
T5980 |
17897-17900 |
VBD |
denotes |
was |
T5981 |
17901-17905 |
VBN |
denotes |
used |
T5982 |
17906-17909 |
IN |
denotes |
for |
T5983 |
17910-17913 |
DT |
denotes |
the |
T5984 |
17914-17923 |
NN |
denotes |
detection |
T5985 |
17924-17926 |
IN |
denotes |
of |
T5986 |
17927-17929 |
NNP |
denotes |
GR |
T5987 |
17929-17930 |
. |
denotes |
. |
T5988 |
17931-17935 |
NNP |
denotes |
FITC |
T5989 |
17936-17939 |
CC |
denotes |
and |
T5990 |
17940-17949 |
JJ |
denotes |
rhodamine |
T5991 |
17950-17956 |
NNS |
denotes |
levels |
T5992 |
17957-17961 |
VBD |
denotes |
were |
T5993 |
17962-17970 |
VBN |
denotes |
measured |
T5994 |
17971-17975 |
IN |
denotes |
with |
T5995 |
17976-17977 |
DT |
denotes |
a |
T5996 |
17978-17989 |
JJ |
denotes |
fluorescent |
T5997 |
17990-18001 |
JJ |
denotes |
micro-plate |
T5998 |
18002-18008 |
NN |
denotes |
reader |
T5999 |
18009-18010 |
-LRB- |
denotes |
( |
T6000 |
18010-18017 |
NNP |
denotes |
Bioline |
T6001 |
18017-18018 |
, |
denotes |
, |
T6002 |
18019-18025 |
NNP |
denotes |
London |
T6003 |
18025-18026 |
, |
denotes |
, |
T6004 |
18027-18029 |
NNP |
denotes |
UK |
T6005 |
18029-18030 |
-RRB- |
denotes |
) |
T6006 |
18030-18031 |
. |
denotes |
. |
T6161 |
18033-18038 |
NNP |
denotes |
NF-κB |
T6162 |
18039-18049 |
NNP |
denotes |
Activation |
T6163 |
18050-18055 |
NNP |
denotes |
NF-κB |
T6164 |
18056-18063 |
JJ |
denotes |
binding |
T6165 |
18064-18072 |
NN |
denotes |
activity |
T6166 |
18073-18075 |
IN |
denotes |
in |
T6167 |
18076-18083 |
JJ |
denotes |
nuclear |
T6168 |
18084-18092 |
NNS |
denotes |
extracts |
T6169 |
18093-18096 |
VBD |
denotes |
was |
T6170 |
18097-18107 |
VBN |
denotes |
determined |
T6171 |
18108-18113 |
VBG |
denotes |
using |
T6172 |
18114-18116 |
DT |
denotes |
an |
T6173 |
18117-18128 |
JJ |
denotes |
ELISA-based |
T6174 |
18129-18132 |
NN |
denotes |
kit |
T6175 |
18133-18134 |
-LRB- |
denotes |
( |
T6176 |
18134-18142 |
JJ |
denotes |
Trans-AM |
T6177 |
18143-18146 |
NNS |
denotes |
p65 |
T6178 |
18146-18147 |
, |
denotes |
, |
T6179 |
18148-18154 |
NNP |
denotes |
Active |
T6180 |
18155-18160 |
NNP |
denotes |
Motif |
T6181 |
18160-18161 |
, |
denotes |
, |
T6182 |
18162-18171 |
NNP |
denotes |
Rixensart |
T6183 |
18171-18172 |
, |
denotes |
, |
T6184 |
18173-18180 |
NNP |
denotes |
Belgium |
T6185 |
18180-18181 |
-RRB- |
denotes |
) |
T6186 |
18181-18182 |
. |
denotes |
. |
T6187 |
18183-18185 |
IN |
denotes |
In |
T6188 |
18186-18191 |
NN |
denotes |
brief |
T6189 |
18191-18192 |
, |
denotes |
, |
T6190 |
18193-18194 |
CD |
denotes |
5 |
T6191 |
18195-18197 |
NN |
denotes |
µg |
T6192 |
18198-18200 |
IN |
denotes |
of |
T6193 |
18201-18208 |
JJ |
denotes |
nuclear |
T6194 |
18209-18217 |
NNS |
denotes |
extracts |
T6195 |
18218-18222 |
VBD |
denotes |
were |
T6196 |
18223-18232 |
VBN |
denotes |
incubated |
T6197 |
18233-18237 |
IN |
denotes |
with |
T6198 |
18238-18239 |
DT |
denotes |
a |
T6199 |
18240-18245 |
NN |
denotes |
plate |
T6200 |
18246-18252 |
VBN |
denotes |
coated |
T6201 |
18253-18257 |
IN |
denotes |
with |
T6202 |
18258-18260 |
DT |
denotes |
an |
T6203 |
18261-18266 |
JJ |
denotes |
NF-κB |
T6204 |
18267-18276 |
NN |
denotes |
consensus |
T6205 |
18277-18292 |
NN |
denotes |
oligonucleotide |
T6206 |
18292-18293 |
. |
denotes |
. |
T6207 |
18294-18300 |
NNS |
denotes |
Plates |
T6208 |
18301-18305 |
VBD |
denotes |
were |
T6209 |
18306-18312 |
VBN |
denotes |
washed |
T6210 |
18313-18319 |
IN |
denotes |
before |
T6211 |
18320-18328 |
NN |
denotes |
addition |
T6212 |
18329-18331 |
IN |
denotes |
of |
T6213 |
18332-18334 |
DT |
denotes |
an |
T6214 |
18335-18343 |
JJ |
denotes |
anti-p65 |
T6215 |
18344-18352 |
NN |
denotes |
antibody |
T6216 |
18352-18353 |
. |
denotes |
. |
T6217 |
18354-18362 |
NN |
denotes |
Antibody |
T6218 |
18363-18370 |
JJ |
denotes |
binding |
T6219 |
18371-18374 |
VBD |
denotes |
was |
T6220 |
18375-18383 |
VBN |
denotes |
detected |
T6221 |
18384-18388 |
IN |
denotes |
with |
T6222 |
18389-18390 |
DT |
denotes |
a |
T6223 |
18391-18400 |
JJ |
denotes |
secondary |
T6224 |
18401-18415 |
JJ |
denotes |
HRP-conjugated |
T6225 |
18416-18424 |
NN |
denotes |
antibody |
T6226 |
18425-18428 |
CC |
denotes |
and |
T6227 |
18429-18438 |
VBN |
denotes |
developed |
T6228 |
18439-18443 |
IN |
denotes |
with |
T6229 |
18444-18447 |
NNP |
denotes |
TMB |
T6230 |
18448-18457 |
NN |
denotes |
substrate |
T6231 |
18457-18458 |
. |
denotes |
. |
T6232 |
18459-18462 |
DT |
denotes |
The |
T6233 |
18463-18472 |
NN |
denotes |
intensity |
T6234 |
18473-18475 |
IN |
denotes |
of |
T6235 |
18476-18479 |
DT |
denotes |
the |
T6236 |
18480-18488 |
NN |
denotes |
reaction |
T6237 |
18489-18492 |
VBD |
denotes |
was |
T6238 |
18493-18501 |
VBN |
denotes |
measured |
T6239 |
18502-18504 |
IN |
denotes |
at |
T6240 |
18505-18508 |
CD |
denotes |
450 |
T6241 |
18509-18511 |
NN |
denotes |
nm |
T6242 |
18511-18512 |
. |
denotes |
. |
T6486 |
18514-18532 |
NNP |
denotes |
Immunofluorescence |
T6487 |
18533-18541 |
NNP |
denotes |
Staining |
T6488 |
18542-18560 |
NNP |
denotes |
Immunofluorescence |
T6489 |
18561-18569 |
VBG |
denotes |
staining |
T6490 |
18570-18573 |
VBD |
denotes |
was |
T6491 |
18574-18583 |
VBN |
denotes |
performed |
T6492 |
18584-18586 |
IN |
denotes |
as |
T6493 |
18587-18597 |
RB |
denotes |
previously |
T6494 |
18598-18607 |
VBN |
denotes |
described |
T6495 |
18608-18609 |
NNP |
denotes |
[ |
T6496 |
18609-18611 |
CD |
denotes |
34 |
T6497 |
18611-18612 |
NNP |
denotes |
] |
T6498 |
18612-18613 |
. |
denotes |
. |
T6499 |
18614-18617 |
DT |
denotes |
All |
T6500 |
18618-18626 |
VBG |
denotes |
staining |
T6501 |
18627-18630 |
VBD |
denotes |
was |
T6502 |
18631-18640 |
VBN |
denotes |
performed |
T6503 |
18641-18643 |
IN |
denotes |
at |
T6504 |
18644-18648 |
NN |
denotes |
room |
T6505 |
18649-18660 |
NN |
denotes |
temperature |
T6506 |
18661-18664 |
CC |
denotes |
and |
T6507 |
18665-18670 |
IN |
denotes |
under |
T6508 |
18671-18685 |
NN |
denotes |
humidification |
T6509 |
18685-18686 |
. |
denotes |
. |
T6510 |
18687-18692 |
NNS |
denotes |
Cells |
T6511 |
18693-18697 |
VBD |
denotes |
were |
T6512 |
18698-18707 |
VBN |
denotes |
collected |
T6513 |
18708-18711 |
CC |
denotes |
and |
T6514 |
18712-18721 |
NNS |
denotes |
cytospins |
T6515 |
18722-18730 |
VBN |
denotes |
prepared |
T6516 |
18731-18733 |
IN |
denotes |
in |
T6517 |
18734-18735 |
DT |
denotes |
a |
T6518 |
18736-18750 |
NN |
denotes |
cytocentrifuge |
T6519 |
18751-18752 |
-LRB- |
denotes |
( |
T6520 |
18752-18759 |
NNP |
denotes |
Shandon |
T6521 |
18760-18762 |
NNP |
denotes |
II |
T6522 |
18762-18763 |
, |
denotes |
, |
T6523 |
18764-18771 |
NNP |
denotes |
Shandon |
T6524 |
18771-18772 |
, |
denotes |
, |
T6525 |
18773-18780 |
NNP |
denotes |
Runcorn |
T6526 |
18780-18781 |
, |
denotes |
, |
T6527 |
18782-18784 |
NNP |
denotes |
UK |
T6528 |
18784-18785 |
-RRB- |
denotes |
) |
T6529 |
18785-18786 |
. |
denotes |
. |
T6530 |
18787-18792 |
NNS |
denotes |
Cells |
T6531 |
18793-18797 |
VBD |
denotes |
were |
T6532 |
18798-18811 |
VBN |
denotes |
permeabilized |
T6533 |
18811-18812 |
, |
denotes |
, |
T6534 |
18813-18820 |
VBN |
denotes |
blocked |
T6535 |
18820-18821 |
, |
denotes |
, |
T6536 |
18822-18825 |
CC |
denotes |
and |
T6537 |
18826-18830 |
RB |
denotes |
then |
T6538 |
18831-18840 |
VBN |
denotes |
incubated |
T6539 |
18841-18845 |
IN |
denotes |
with |
T6540 |
18846-18848 |
NNP |
denotes |
GR |
T6541 |
18849-18850 |
-LRB- |
denotes |
( |
T6542 |
18850-18851 |
CD |
denotes |
1 |
T6543 |
18851-18852 |
CD |
denotes |
∶ |
T6544 |
18852-18854 |
CD |
denotes |
50 |
T6545 |
18855-18859 |
NN |
denotes |
E-20 |
T6546 |
18860-18865 |
NNP |
denotes |
Santa |
T6547 |
18866-18870 |
NNP |
denotes |
Cruz |
T6548 |
18871-18884 |
NNP |
denotes |
Biotechnology |
T6549 |
18884-18885 |
-RRB- |
denotes |
) |
T6550 |
18886-18888 |
CC |
denotes |
or |
T6551 |
18889-18900 |
JJ |
denotes |
anti-GATA-3 |
T6552 |
18901-18902 |
-LRB- |
denotes |
( |
T6553 |
18902-18906 |
JJ |
denotes |
H-48 |
T6554 |
18906-18907 |
: |
denotes |
; |
T6555 |
18908-18913 |
NNP |
denotes |
Santa |
T6556 |
18914-18918 |
NNP |
denotes |
Cruz |
T6557 |
18919-18932 |
NNP |
denotes |
Biotechnology |
T6558 |
18932-18933 |
-RRB- |
denotes |
) |
T6559 |
18934-18942 |
NN |
denotes |
antibody |
T6560 |
18943-18946 |
IN |
denotes |
for |
T6561 |
18947-18948 |
CD |
denotes |
1 |
T6562 |
18949-18950 |
NN |
denotes |
h |
T6563 |
18951-18953 |
IN |
denotes |
at |
T6564 |
18954-18958 |
NN |
denotes |
room |
T6565 |
18959-18970 |
NN |
denotes |
temperature |
T6566 |
18970-18971 |
. |
denotes |
. |
T6567 |
18972-18977 |
IN |
denotes |
After |
T6568 |
18978-18983 |
CD |
denotes |
three |
T6569 |
18984-18990 |
NNS |
denotes |
washes |
T6570 |
18991-18993 |
IN |
denotes |
in |
T6571 |
18994-19012 |
JJ |
denotes |
phosphate-buffered |
T6572 |
19013-19019 |
NN |
denotes |
saline |
T6573 |
19020-19021 |
-LRB- |
denotes |
( |
T6574 |
19021-19024 |
NNP |
denotes |
PBS |
T6575 |
19024-19025 |
-RRB- |
denotes |
) |
T6576 |
19025-19026 |
, |
denotes |
, |
T6577 |
19027-19032 |
NNS |
denotes |
cells |
T6578 |
19033-19037 |
VBD |
denotes |
were |
T6579 |
19038-19047 |
VBN |
denotes |
incubated |
T6580 |
19048-19052 |
IN |
denotes |
with |
T6581 |
19053-19067 |
JJ |
denotes |
tetrarhodamine |
T6582 |
19068-19082 |
NN |
denotes |
isothiocyanate |
T6583 |
19083-19093 |
VBN |
denotes |
conjugated |
T6584 |
19094-19098 |
NN |
denotes |
goat |
T6585 |
19099-19110 |
JJ |
denotes |
anti-rabbit |
T6586 |
19111-19119 |
NN |
denotes |
antibody |
T6587 |
19120-19121 |
-LRB- |
denotes |
( |
T6588 |
19121-19125 |
NNP |
denotes |
Dako |
T6589 |
19125-19126 |
-RRB- |
denotes |
) |
T6590 |
19126-19127 |
. |
denotes |
. |
T6591 |
19128-19137 |
NNS |
denotes |
Cytospins |
T6592 |
19138-19142 |
VBD |
denotes |
were |
T6593 |
19143-19157 |
VBN |
denotes |
counterstained |
T6594 |
19158-19162 |
IN |
denotes |
with |
T6595 |
19163-19164 |
CD |
denotes |
4 |
T6596 |
19164-19165 |
CD |
denotes |
′ |
T6597 |
19165-19167 |
SYM |
denotes |
,6 |
T6598 |
19167-19168 |
: |
denotes |
- |
T6599 |
19168-19192 |
JJ |
denotes |
diamidino-2-phenylindole |
T6600 |
19193-19208 |
NN |
denotes |
dihydrochloride |
T6601 |
19209-19210 |
-LRB- |
denotes |
( |
T6602 |
19210-19214 |
NNP |
denotes |
DAPI |
T6603 |
19214-19215 |
-RRB- |
denotes |
) |
T6604 |
19215-19216 |
, |
denotes |
, |
T6605 |
19217-19218 |
DT |
denotes |
a |
T6606 |
19219-19230 |
JJ |
denotes |
fluorescent |
T6607 |
19231-19235 |
JJ |
denotes |
blue |
T6608 |
19236-19243 |
JJ |
denotes |
nuclear |
T6609 |
19244-19250 |
NN |
denotes |
indole |
T6610 |
19251-19260 |
NN |
denotes |
chromatin |
T6611 |
19261-19266 |
VBP |
denotes |
stain |
T6612 |
19266-19267 |
, |
denotes |
, |
T6613 |
19268-19271 |
CC |
denotes |
and |
T6614 |
19272-19279 |
VBD |
denotes |
mounted |
T6615 |
19280-19282 |
IN |
denotes |
in |
T6616 |
19283-19286 |
NNP |
denotes |
PBS |
T6617 |
19286-19287 |
: |
denotes |
: |
T6618 |
19287-19295 |
NN |
denotes |
glycerol |
T6619 |
19296-19297 |
-LRB- |
denotes |
( |
T6620 |
19297-19299 |
CD |
denotes |
50 |
T6621 |
19299-19300 |
NN |
denotes |
∶ |
T6622 |
19300-19302 |
CD |
denotes |
50 |
T6623 |
19302-19303 |
-RRB- |
denotes |
) |
T6624 |
19303-19304 |
. |
denotes |
. |
T6625 |
19305-19308 |
DT |
denotes |
The |
T6626 |
19309-19323 |
JJ |
denotes |
immunopositive |
T6627 |
19324-19330 |
NN |
denotes |
signal |
T6628 |
19331-19334 |
VBD |
denotes |
was |
T6629 |
19335-19348 |
VBN |
denotes |
characterised |
T6630 |
19349-19354 |
VBG |
denotes |
using |
T6631 |
19355-19360 |
NN |
denotes |
laser |
T6632 |
19361-19369 |
VBG |
denotes |
scanning |
T6633 |
19370-19378 |
JJ |
denotes |
confocal |
T6634 |
19379-19389 |
NN |
denotes |
microscopy |
T6635 |
19390-19392 |
IN |
denotes |
on |
T6636 |
19393-19394 |
DT |
denotes |
a |
T6637 |
19395-19400 |
NNP |
denotes |
Leica |
T6638 |
19401-19404 |
NNP |
denotes |
TCS |
T6639 |
19405-19410 |
NNP |
denotes |
NT/SP |
T6640 |
19411-19422 |
JJ |
denotes |
interactive |
T6641 |
19423-19428 |
NN |
denotes |
laser |
T6642 |
19429-19438 |
NN |
denotes |
cytometer |
T6643 |
19439-19447 |
VBN |
denotes |
equipped |
T6644 |
19448-19452 |
IN |
denotes |
with |
T6645 |
19453-19461 |
JJ |
denotes |
confocal |
T6646 |
19462-19468 |
NNS |
denotes |
optics |
T6647 |
19469-19470 |
-LRB- |
denotes |
( |
T6648 |
19470-19475 |
NNP |
denotes |
Leica |
T6649 |
19476-19488 |
NNP |
denotes |
Microsystems |
T6650 |
19488-19489 |
, |
denotes |
, |
T6651 |
19490-19497 |
NNP |
denotes |
Wetzlar |
T6652 |
19497-19498 |
, |
denotes |
, |
T6653 |
19499-19506 |
NNP |
denotes |
Germany |
T6654 |
19506-19507 |
-RRB- |
denotes |
) |
T6655 |
19507-19508 |
. |
denotes |
. |
T6656 |
19509-19511 |
TO |
denotes |
To |
T6657 |
19512-19521 |
VB |
denotes |
determine |
T6658 |
19522-19525 |
DT |
denotes |
the |
T6659 |
19526-19537 |
NN |
denotes |
specificity |
T6660 |
19538-19540 |
IN |
denotes |
of |
T6661 |
19541-19544 |
DT |
denotes |
the |
T6662 |
19545-19555 |
NNS |
denotes |
antibodies |
T6663 |
19555-19556 |
, |
denotes |
, |
T6664 |
19557-19563 |
NN |
denotes |
rabbit |
T6665 |
19564-19569 |
NN |
denotes |
serum |
T6666 |
19570-19584 |
NN |
denotes |
immunoglobulin |
T6667 |
19585-19586 |
-LRB- |
denotes |
( |
T6668 |
19586-19590 |
NNP |
denotes |
Dako |
T6669 |
19590-19591 |
-RRB- |
denotes |
) |
T6670 |
19592-19595 |
CC |
denotes |
and |
T6671 |
19596-19605 |
JJ |
denotes |
secondary |
T6672 |
19606-19616 |
NNS |
denotes |
antibodies |
T6673 |
19617-19624 |
IN |
denotes |
without |
T6674 |
19625-19628 |
DT |
denotes |
the |
T6675 |
19629-19636 |
JJ |
denotes |
primary |
T6676 |
19637-19641 |
VBD |
denotes |
were |
T6677 |
19642-19646 |
VBN |
denotes |
used |
T6678 |
19647-19649 |
IN |
denotes |
as |
T6679 |
19650-19658 |
NNS |
denotes |
controls |
T6680 |
19658-19659 |
. |
denotes |
. |
T6681 |
19660-19670 |
RB |
denotes |
Positively |
T6682 |
19671-19678 |
VBN |
denotes |
stained |
T6683 |
19679-19685 |
NNS |
denotes |
nuclei |
T6684 |
19686-19689 |
CC |
denotes |
and |
T6685 |
19690-19695 |
JJ |
denotes |
total |
T6686 |
19696-19701 |
NNS |
denotes |
cells |
T6687 |
19702-19706 |
VBD |
denotes |
were |
T6688 |
19707-19714 |
VBN |
denotes |
counted |
T6689 |
19715-19716 |
-LRB- |
denotes |
( |
T6690 |
19716-19719 |
CD |
denotes |
500 |
T6691 |
19719-19720 |
-RRB- |
denotes |
) |
T6692 |
19721-19723 |
IN |
denotes |
on |
T6693 |
19724-19728 |
DT |
denotes |
each |
T6694 |
19729-19734 |
NN |
denotes |
slide |
T6695 |
19735-19739 |
IN |
denotes |
with |
T6696 |
19740-19743 |
DT |
denotes |
the |
T6697 |
19744-19752 |
NN |
denotes |
observer |
T6698 |
19753-19760 |
VBD |
denotes |
blinded |
T6699 |
19761-19763 |
TO |
denotes |
to |
T6700 |
19764-19767 |
DT |
denotes |
the |
T6701 |
19768-19777 |
NN |
denotes |
treatment |
T6702 |
19777-19778 |
. |
denotes |
. |
T6937 |
19780-19790 |
NNP |
denotes |
GATA-3-GFP |
T6938 |
19791-19800 |
NNP |
denotes |
Construct |
T6939 |
19801-19804 |
NNP |
denotes |
The |
T6940 |
19805-19811 |
NNP |
denotes |
GATA-3 |
T6941 |
19812-19817 |
NN |
denotes |
clone |
T6942 |
19818-19819 |
-LRB- |
denotes |
( |
T6943 |
19819-19827 |
NNP |
denotes |
BC003070 |
T6944 |
19827-19828 |
-RRB- |
denotes |
) |
T6945 |
19829-19837 |
JJ |
denotes |
complete |
T6946 |
19838-19842 |
NNP |
denotes |
cDNA |
T6947 |
19843-19846 |
VBD |
denotes |
was |
T6948 |
19847-19855 |
VBN |
denotes |
obtained |
T6949 |
19856-19860 |
IN |
denotes |
from |
T6950 |
19861-19871 |
NNP |
denotes |
Invitrogen |
T6951 |
19872-19876 |
NNP |
denotes |
Life |
T6952 |
19877-19889 |
NNPS |
denotes |
Technologies |
T6953 |
19890-19892 |
IN |
denotes |
as |
T6954 |
19893-19894 |
DT |
denotes |
a |
T6955 |
19895-19896 |
CD |
denotes |
5 |
T6956 |
19896-19897 |
SYM |
denotes |
′ |
T6957 |
19897-19898 |
: |
denotes |
- |
T6958 |
19899-19906 |
JJ |
denotes |
EcoRI/3 |
T6959 |
19906-19907 |
SYM |
denotes |
′ |
T6960 |
19907-19908 |
: |
denotes |
- |
T6961 |
19908-19912 |
NNP |
denotes |
XhoI |
T6962 |
19913-19919 |
NN |
denotes |
insert |
T6963 |
19920-19922 |
IN |
denotes |
of |
T6964 |
19923-19929 |
NN |
denotes |
GATA-3 |
T6965 |
19930-19932 |
IN |
denotes |
in |
T6966 |
19933-19936 |
DT |
denotes |
the |
T6967 |
19937-19942 |
NNP |
denotes |
pOTB7 |
T6968 |
19943-19949 |
NN |
denotes |
vector |
T6969 |
19949-19950 |
. |
denotes |
. |
T6970 |
19951-19957 |
NN |
denotes |
GATA-3 |
T6971 |
19958-19961 |
VBD |
denotes |
was |
T6972 |
19962-19969 |
VBN |
denotes |
excised |
T6973 |
19970-19974 |
IN |
denotes |
from |
T6974 |
19975-19980 |
NNP |
denotes |
pOTB7 |
T6975 |
19981-19986 |
VBG |
denotes |
using |
T6976 |
19987-19991 |
NNP |
denotes |
XhoI |
T6977 |
19992-20001 |
NN |
denotes |
digestion |
T6978 |
20002-20005 |
CC |
denotes |
and |
T6979 |
20006-20014 |
NN |
denotes |
pEGFP-C2 |
T6980 |
20015-20016 |
-LRB- |
denotes |
( |
T6981 |
20016-20024 |
NNP |
denotes |
Clontech |
T6982 |
20024-20025 |
, |
denotes |
, |
T6983 |
20026-20047 |
NNP |
denotes |
Saint-Germain-en-Laye |
T6984 |
20047-20048 |
, |
denotes |
, |
T6985 |
20049-20055 |
NNP |
denotes |
France |
T6986 |
20055-20056 |
-RRB- |
denotes |
) |
T6987 |
20057-20060 |
VBD |
denotes |
was |
T6988 |
20061-20069 |
VBN |
denotes |
digested |
T6989 |
20070-20074 |
IN |
denotes |
with |
T6990 |
20075-20080 |
NNP |
denotes |
BamHI |
T6991 |
20080-20081 |
. |
denotes |
. |
T6992 |
20082-20085 |
NNP |
denotes |
DNA |
T6993 |
20086-20089 |
VBD |
denotes |
was |
T6994 |
20090-20099 |
VBN |
denotes |
recovered |
T6995 |
20100-20102 |
IN |
denotes |
by |
T6996 |
20103-20109 |
NN |
denotes |
phenol |
T6997 |
20110-20120 |
NN |
denotes |
extraction |
T6998 |
20121-20124 |
CC |
denotes |
and |
T6999 |
20125-20132 |
NN |
denotes |
ethanol |
T7000 |
20133-20146 |
NN |
denotes |
precipitation |
T7001 |
20146-20147 |
, |
denotes |
, |
T7002 |
20148-20151 |
CC |
denotes |
and |
T7003 |
20152-20156 |
DT |
denotes |
both |
T7004 |
20157-20160 |
DT |
denotes |
the |
T7005 |
20161-20167 |
NNP |
denotes |
GATA-3 |
T7006 |
20168-20176 |
NN |
denotes |
fragment |
T7007 |
20177-20180 |
CC |
denotes |
and |
T7008 |
20181-20184 |
DT |
denotes |
the |
T7009 |
20185-20193 |
NN |
denotes |
pEGFP-C2 |
T7010 |
20194-20200 |
NN |
denotes |
vector |
T7011 |
20201-20212 |
JJ |
denotes |
blunt-ended |
T7012 |
20213-20215 |
IN |
denotes |
by |
T7013 |
20216-20226 |
NN |
denotes |
incubation |
T7014 |
20227-20231 |
IN |
denotes |
with |
T7015 |
20232-20238 |
NNP |
denotes |
Klenow |
T7016 |
20239-20240 |
-LRB- |
denotes |
( |
T7017 |
20240-20247 |
NNP |
denotes |
Bioline |
T7018 |
20248-20257 |
NNP |
denotes |
Bio-27029 |
T7019 |
20257-20258 |
-RRB- |
denotes |
) |
T7020 |
20259-20262 |
IN |
denotes |
for |
T7021 |
20263-20265 |
CD |
denotes |
30 |
T7022 |
20266-20269 |
NN |
denotes |
min |
T7023 |
20270-20272 |
IN |
denotes |
at |
T7024 |
20273-20275 |
CD |
denotes |
37 |
T7025 |
20275-20276 |
CD |
denotes |
° |
T7026 |
20276-20278 |
NNP |
denotes |
C. |
T7027 |
20279-20285 |
NNP |
denotes |
Klenow |
T7028 |
20286-20289 |
VBD |
denotes |
was |
T7029 |
20290-20301 |
VBN |
denotes |
inactivated |
T7030 |
20302-20304 |
IN |
denotes |
by |
T7031 |
20305-20315 |
NN |
denotes |
incubation |
T7032 |
20316-20319 |
IN |
denotes |
for |
T7033 |
20320-20322 |
CD |
denotes |
10 |
T7034 |
20323-20326 |
NN |
denotes |
min |
T7035 |
20327-20329 |
IN |
denotes |
at |
T7036 |
20330-20332 |
CD |
denotes |
75 |
T7037 |
20332-20333 |
CD |
denotes |
° |
T7038 |
20333-20335 |
NNP |
denotes |
C. |
T7039 |
20336-20339 |
NNP |
denotes |
DNA |
T7040 |
20340-20343 |
VBD |
denotes |
was |
T7041 |
20344-20353 |
VBN |
denotes |
recovered |
T7042 |
20354-20356 |
IN |
denotes |
by |
T7043 |
20357-20363 |
NN |
denotes |
phenol |
T7044 |
20364-20374 |
NN |
denotes |
extraction |
T7045 |
20375-20378 |
CC |
denotes |
and |
T7046 |
20379-20386 |
NN |
denotes |
ethanol |
T7047 |
20387-20400 |
NN |
denotes |
precipitation |
T7048 |
20400-20401 |
, |
denotes |
, |
T7049 |
20402-20405 |
CC |
denotes |
and |
T7050 |
20406-20410 |
DT |
denotes |
both |
T7051 |
20411-20414 |
DT |
denotes |
the |
T7052 |
20415-20426 |
JJ |
denotes |
blunt-ended |
T7053 |
20427-20433 |
JJ |
denotes |
GATA-3 |
T7054 |
20434-20442 |
NN |
denotes |
fragment |
T7055 |
20443-20446 |
CC |
denotes |
and |
T7056 |
20447-20450 |
DT |
denotes |
the |
T7057 |
20451-20454 |
NNP |
denotes |
GFP |
T7058 |
20455-20461 |
NN |
denotes |
vector |
T7059 |
20462-20466 |
VBD |
denotes |
were |
T7060 |
20467-20479 |
RB |
denotes |
subsequently |
T7061 |
20480-20488 |
VBN |
denotes |
digested |
T7062 |
20489-20493 |
IN |
denotes |
with |
T7063 |
20494-20499 |
NNP |
denotes |
EcoRI |
T7064 |
20500-20506 |
IN |
denotes |
before |
T7065 |
20507-20510 |
DT |
denotes |
the |
T7066 |
20511-20512 |
CD |
denotes |
5 |
T7067 |
20512-20513 |
SYM |
denotes |
′ |
T7068 |
20513-20514 |
: |
denotes |
- |
T7069 |
20514-20521 |
JJ |
denotes |
EcoRI/3 |
T7070 |
20521-20522 |
NN |
denotes |
′ |
T7071 |
20523-20528 |
JJ |
denotes |
blunt |
T7072 |
20529-20532 |
NN |
denotes |
end |
T7073 |
20533-20539 |
NN |
denotes |
GATA-3 |
T7074 |
20540-20548 |
NN |
denotes |
fragment |
T7075 |
20549-20552 |
VBD |
denotes |
was |
T7076 |
20553-20561 |
VBN |
denotes |
inserted |
T7077 |
20562-20566 |
IN |
denotes |
into |
T7078 |
20567-20570 |
DT |
denotes |
the |
T7079 |
20571-20572 |
CD |
denotes |
5 |
T7080 |
20572-20573 |
SYM |
denotes |
′ |
T7081 |
20573-20574 |
: |
denotes |
- |
T7082 |
20574-20581 |
JJ |
denotes |
EcoRI/3 |
T7083 |
20581-20582 |
NN |
denotes |
′ |
T7084 |
20583-20588 |
JJ |
denotes |
blunt |
T7085 |
20589-20594 |
VBN |
denotes |
ended |
T7086 |
20595-20598 |
NNP |
denotes |
GFP |
T7087 |
20599-20605 |
NN |
denotes |
vector |
T7088 |
20605-20606 |
. |
denotes |
. |
T7089 |
20607-20615 |
JJ |
denotes |
Positive |
T7090 |
20616-20622 |
NNS |
denotes |
clones |
T7091 |
20623-20627 |
VBD |
denotes |
were |
T7092 |
20628-20637 |
VBN |
denotes |
confirmed |
T7093 |
20638-20640 |
IN |
denotes |
by |
T7094 |
20641-20650 |
NN |
denotes |
digestion |
T7095 |
20651-20654 |
CC |
denotes |
and |
T7096 |
20655-20659 |
NN |
denotes |
size |
T7097 |
20660-20668 |
NN |
denotes |
analysis |
T7098 |
20669-20671 |
IN |
denotes |
by |
T7099 |
20672-20673 |
CD |
denotes |
1 |
T7100 |
20673-20674 |
NN |
denotes |
% |
T7101 |
20675-20682 |
JJ |
denotes |
agarose |
T7102 |
20683-20686 |
NN |
denotes |
gel |
T7103 |
20687-20702 |
NN |
denotes |
electrophoresis |
T7104 |
20703-20706 |
CC |
denotes |
and |
T7105 |
20707-20709 |
IN |
denotes |
by |
T7106 |
20710-20720 |
VBG |
denotes |
sequencing |
T7107 |
20720-20721 |
. |
denotes |
. |
T7254 |
20723-20735 |
NNP |
denotes |
Transfection |
T7255 |
20736-20742 |
NNP |
denotes |
HuT-78 |
T7256 |
20743-20748 |
NNS |
denotes |
cells |
T7257 |
20749-20753 |
VBD |
denotes |
were |
T7258 |
20754-20765 |
VBN |
denotes |
transfected |
T7259 |
20766-20770 |
IN |
denotes |
with |
T7260 |
20771-20777 |
DT |
denotes |
either |
T7261 |
20778-20781 |
CD |
denotes |
EP8 |
T7262 |
20782-20784 |
CC |
denotes |
or |
T7263 |
20785-20788 |
NNP |
denotes |
GFP |
T7264 |
20789-20795 |
NN |
denotes |
vector |
T7265 |
20796-20800 |
RB |
denotes |
only |
T7266 |
20801-20804 |
NNP |
denotes |
DNA |
T7267 |
20805-20810 |
VBG |
denotes |
using |
T7268 |
20811-20819 |
NN |
denotes |
solution |
T7269 |
20820-20821 |
NN |
denotes |
R |
T7270 |
20821-20822 |
, |
denotes |
, |
T7271 |
20823-20832 |
NN |
denotes |
programme |
T7272 |
20833-20838 |
NN |
denotes |
V-001 |
T7273 |
20839-20841 |
IN |
denotes |
at |
T7274 |
20842-20843 |
DT |
denotes |
a |
T7275 |
20844-20849 |
NN |
denotes |
ratio |
T7276 |
20850-20852 |
IN |
denotes |
of |
T7277 |
20853-20854 |
CD |
denotes |
3 |
T7278 |
20854-20855 |
CD |
denotes |
× |
T7279 |
20855-20858 |
CD |
denotes |
106 |
T7280 |
20859-20866 |
CD |
denotes |
cells/4 |
T7281 |
20867-20869 |
NN |
denotes |
µg |
T7282 |
20870-20873 |
NN |
denotes |
DNA |
T7283 |
20874-20877 |
IN |
denotes |
for |
T7284 |
20878-20879 |
CD |
denotes |
7 |
T7285 |
20880-20881 |
CD |
denotes |
8 |
T7286 |
20882-20883 |
NN |
denotes |
h |
T7287 |
20884-20886 |
IN |
denotes |
in |
T7288 |
20887-20895 |
JJ |
denotes |
complete |
T7289 |
20896-20902 |
NN |
denotes |
medium |
T7290 |
20903-20904 |
-LRB- |
denotes |
( |
T7291 |
20904-20906 |
CD |
denotes |
10 |
T7292 |
20906-20907 |
NN |
denotes |
% |
T7293 |
20908-20914 |
JJ |
denotes |
bovine |
T7294 |
20915-20920 |
NN |
denotes |
serum |
T7295 |
20921-20923 |
IN |
denotes |
in |
T7296 |
20924-20932 |
NNP |
denotes |
RPMI1640 |
T7297 |
20932-20935 |
CD |
denotes |
+15 |
T7298 |
20936-20947 |
NN |
denotes |
L-glutamine |
T7299 |
20947-20948 |
-RRB- |
denotes |
) |
T7300 |
20949-20958 |
VBG |
denotes |
according |
T7301 |
20959-20961 |
TO |
denotes |
to |
T7302 |
20962-20965 |
DT |
denotes |
the |
T7303 |
20966-20973 |
JJ |
denotes |
general |
T7304 |
20974-20979 |
NNP |
denotes |
Amaxa |
T7305 |
20980-20988 |
NN |
denotes |
protocol |
T7306 |
20989-20992 |
IN |
denotes |
for |
T7307 |
20993-21006 |
NN |
denotes |
nucleofection |
T7308 |
21006-21007 |
. |
denotes |
. |
T7309 |
21008-21011 |
DT |
denotes |
The |
T7310 |
21012-21018 |
NN |
denotes |
medium |
T7311 |
21019-21022 |
VBD |
denotes |
was |
T7312 |
21023-21035 |
RB |
denotes |
subsequently |
T7313 |
21036-21043 |
VBN |
denotes |
changed |
T7314 |
21044-21046 |
TO |
denotes |
to |
T7315 |
21047-21048 |
CD |
denotes |
1 |
T7316 |
21048-21049 |
NN |
denotes |
% |
T7317 |
21050-21054 |
NNP |
denotes |
RPMI |
T7318 |
21055-21058 |
IN |
denotes |
for |
T7319 |
21059-21061 |
CD |
denotes |
24 |
T7320 |
21062-21063 |
NN |
denotes |
h |
T7321 |
21064-21070 |
IN |
denotes |
before |
T7322 |
21071-21082 |
VBN |
denotes |
transfected |
T7323 |
21083-21088 |
NNS |
denotes |
cells |
T7324 |
21089-21093 |
VBD |
denotes |
were |
T7325 |
21094-21099 |
VBN |
denotes |
added |
T7326 |
21100-21102 |
TO |
denotes |
to |
T7327 |
21103-21111 |
JJ |
denotes |
anti-CD3 |
T7328 |
21111-21112 |
NN |
denotes |
/ |
T7329 |
21112-21116 |
CD |
denotes |
CD28 |
T7330 |
21117-21124 |
VBN |
denotes |
treated |
T7331 |
21125-21130 |
NNS |
denotes |
wells |
T7332 |
21131-21134 |
CC |
denotes |
and |
T7333 |
21135-21139 |
VBP |
denotes |
live |
T7334 |
21140-21144 |
NN |
denotes |
cell |
T7335 |
21145-21160 |
JJ |
denotes |
videomicroscopy |
T7336 |
21161-21170 |
VBN |
denotes |
performed |
T7337 |
21170-21171 |
. |
denotes |
. |
T7473 |
21173-21183 |
NNP |
denotes |
Time-Lapse |
T7474 |
21184-21194 |
NNP |
denotes |
Microscopy |
T7475 |
21195-21201 |
NNP |
denotes |
HuT-78 |
T7476 |
21202-21207 |
NNS |
denotes |
cells |
T7477 |
21208-21218 |
VBG |
denotes |
expressing |
T7478 |
21219-21229 |
NNP |
denotes |
GATA-3-GFP |
T7479 |
21230-21234 |
VBD |
denotes |
were |
T7480 |
21235-21245 |
VBN |
denotes |
maintained |
T7481 |
21246-21248 |
IN |
denotes |
at |
T7482 |
21249-21251 |
CD |
denotes |
37 |
T7483 |
21251-21252 |
CD |
denotes |
° |
T7484 |
21252-21253 |
NNP |
denotes |
C |
T7485 |
21254-21256 |
IN |
denotes |
in |
T7486 |
21257-21263 |
NN |
denotes |
growth |
T7487 |
21264-21270 |
NN |
denotes |
medium |
T7488 |
21271-21273 |
IN |
denotes |
in |
T7489 |
21274-21275 |
DT |
denotes |
a |
T7490 |
21276-21282 |
JJ |
denotes |
closed |
T7491 |
21283-21287 |
CD |
denotes |
FCS2 |
T7492 |
21288-21297 |
NN |
denotes |
perfusion |
T7493 |
21298-21305 |
NN |
denotes |
chamber |
T7494 |
21306-21307 |
-LRB- |
denotes |
( |
T7495 |
21307-21316 |
NNPS |
denotes |
Bioptechs |
T7496 |
21316-21317 |
, |
denotes |
, |
T7497 |
21318-21324 |
NNP |
denotes |
Butler |
T7498 |
21324-21325 |
, |
denotes |
, |
T7499 |
21326-21338 |
NNP |
denotes |
Pennsylvania |
T7500 |
21338-21339 |
, |
denotes |
, |
T7501 |
21340-21343 |
NNP |
denotes |
USA |
T7502 |
21343-21344 |
-RRB- |
denotes |
) |
T7503 |
21345-21353 |
VBN |
denotes |
combined |
T7504 |
21354-21358 |
IN |
denotes |
with |
T7505 |
21359-21361 |
DT |
denotes |
an |
T7506 |
21362-21371 |
JJ |
denotes |
objective |
T7507 |
21372-21378 |
NN |
denotes |
heater |
T7508 |
21379-21380 |
-LRB- |
denotes |
( |
T7509 |
21380-21389 |
NNPS |
denotes |
Bioptechs |
T7510 |
21389-21390 |
-RRB- |
denotes |
) |
T7511 |
21391-21393 |
IN |
denotes |
on |
T7512 |
21394-21397 |
DT |
denotes |
the |
T7513 |
21398-21403 |
NN |
denotes |
stage |
T7514 |
21404-21405 |
DT |
denotes |
a |
T7515 |
21406-21411 |
NNP |
denotes |
Zeiss |
T7516 |
21412-21420 |
NNP |
denotes |
Axiovert |
T7517 |
21421-21424 |
CD |
denotes |
200 |
T7518 |
21425-21435 |
NN |
denotes |
microscope |
T7519 |
21436-21437 |
-LRB- |
denotes |
( |
T7520 |
21437-21446 |
NNP |
denotes |
Thornwood |
T7521 |
21446-21447 |
, |
denotes |
, |
T7522 |
21448-21451 |
NNP |
denotes |
New |
T7523 |
21452-21456 |
NNP |
denotes |
York |
T7524 |
21456-21457 |
, |
denotes |
, |
T7525 |
21458-21461 |
NNP |
denotes |
USA |
T7526 |
21461-21462 |
-RRB- |
denotes |
) |
T7527 |
21462-21463 |
. |
denotes |
. |
T7528 |
21464-21476 |
NNS |
denotes |
Observations |
T7529 |
21477-21481 |
VBD |
denotes |
were |
T7530 |
21482-21486 |
VBN |
denotes |
made |
T7531 |
21487-21489 |
IN |
denotes |
by |
T7532 |
21490-21492 |
CD |
denotes |
40 |
T7533 |
21492-21493 |
CD |
denotes |
× |
T7534 |
21493-21496 |
CD |
denotes |
1.0 |
T7535 |
21497-21499 |
NNP |
denotes |
NA |
T7536 |
21500-21513 |
NN |
denotes |
oil-immersion |
T7537 |
21514-21523 |
NN |
denotes |
objective |
T7538 |
21524-21528 |
NN |
denotes |
lens |
T7539 |
21528-21529 |
, |
denotes |
, |
T7540 |
21530-21533 |
CC |
denotes |
and |
T7541 |
21534-21546 |
NN |
denotes |
fluorescence |
T7542 |
21547-21550 |
CC |
denotes |
and |
T7543 |
21551-21556 |
NN |
denotes |
phase |
T7544 |
21557-21565 |
NN |
denotes |
contrast |
T7545 |
21566-21572 |
NNS |
denotes |
images |
T7546 |
21573-21577 |
VBD |
denotes |
were |
T7547 |
21578-21586 |
VBN |
denotes |
gathered |
T7548 |
21587-21592 |
VBG |
denotes |
using |
T7549 |
21593-21594 |
DT |
denotes |
a |
T7550 |
21595-21604 |
NNP |
denotes |
Hamamatsu |
T7551 |
21605-21612 |
NNP |
denotes |
ORCA-ER |
T7552 |
21613-21620 |
VBD |
denotes |
charged |
T7553 |
21621-21628 |
VBN |
denotes |
coupled |
T7554 |
21629-21635 |
NN |
denotes |
device |
T7555 |
21636-21642 |
NN |
denotes |
camera |
T7556 |
21643-21644 |
-LRB- |
denotes |
( |
T7557 |
21644-21655 |
NNP |
denotes |
Bridgewater |
T7558 |
21655-21656 |
, |
denotes |
, |
T7559 |
21657-21660 |
NNP |
denotes |
New |
T7560 |
21661-21667 |
NNP |
denotes |
Jersey |
T7561 |
21667-21668 |
, |
denotes |
, |
T7562 |
21669-21672 |
NNP |
denotes |
USA |
T7563 |
21672-21673 |
-RRB- |
denotes |
) |
T7564 |
21674-21680 |
VBN |
denotes |
driven |
T7565 |
21681-21683 |
IN |
denotes |
by |
T7566 |
21684-21691 |
NNP |
denotes |
Openlab |
T7567 |
21692-21700 |
NN |
denotes |
software |
T7568 |
21701-21702 |
-LRB- |
denotes |
( |
T7569 |
21702-21713 |
NNP |
denotes |
Improvision |
T7570 |
21713-21714 |
, |
denotes |
, |
T7571 |
21715-21723 |
NNP |
denotes |
Coventry |
T7572 |
21723-21724 |
, |
denotes |
, |
T7573 |
21725-21727 |
NNP |
denotes |
UK |
T7574 |
21727-21728 |
-RRB- |
denotes |
) |
T7575 |
21728-21729 |
. |
denotes |
. |
T7576 |
21730-21741 |
NNS |
denotes |
Photographs |
T7577 |
21742-21746 |
VBD |
denotes |
were |
T7578 |
21747-21752 |
VBN |
denotes |
taken |
T7579 |
21753-21755 |
IN |
denotes |
at |
T7580 |
21756-21757 |
CD |
denotes |
0 |
T7581 |
21757-21758 |
, |
denotes |
, |
T7582 |
21759-21761 |
CD |
denotes |
30 |
T7583 |
21761-21762 |
, |
denotes |
, |
T7584 |
21763-21765 |
CD |
denotes |
60 |
T7585 |
21765-21766 |
, |
denotes |
, |
T7586 |
21767-21770 |
CD |
denotes |
120 |
T7587 |
21770-21771 |
, |
denotes |
, |
T7588 |
21772-21775 |
CC |
denotes |
and |
T7589 |
21776-21779 |
CD |
denotes |
240 |
T7590 |
21780-21783 |
NN |
denotes |
min |
T7591 |
21783-21784 |
. |
denotes |
. |
T7691 |
21786-21799 |
NNP |
denotes |
Densitometric |
T7692 |
21800-21808 |
NNP |
denotes |
Analysis |
T7693 |
21809-21821 |
NNP |
denotes |
Densitometry |
T7694 |
21822-21824 |
IN |
denotes |
of |
T7695 |
21825-21828 |
NNP |
denotes |
ECL |
T7696 |
21829-21840 |
NNS |
denotes |
immunoblots |
T7697 |
21841-21844 |
VBD |
denotes |
was |
T7698 |
21845-21854 |
VBN |
denotes |
performed |
T7699 |
21855-21860 |
VBG |
denotes |
using |
T7700 |
21861-21869 |
NNP |
denotes |
Gelworks |
T7701 |
21870-21872 |
NNP |
denotes |
ID |
T7702 |
21873-21885 |
JJ |
denotes |
intermediate |
T7703 |
21886-21894 |
NN |
denotes |
software |
T7704 |
21895-21896 |
-LRB- |
denotes |
( |
T7705 |
21896-21907 |
NNP |
denotes |
Ultraviolet |
T7706 |
21908-21916 |
NNPS |
denotes |
Products |
T7707 |
21916-21917 |
, |
denotes |
, |
T7708 |
21918-21932 |
NNP |
denotes |
Cambridgeshire |
T7709 |
21932-21933 |
, |
denotes |
, |
T7710 |
21934-21936 |
NNP |
denotes |
UK |
T7711 |
21936-21937 |
-RRB- |
denotes |
) |
T7712 |
21937-21938 |
. |
denotes |
. |
T7713 |
21939-21946 |
RB |
denotes |
Briefly |
T7714 |
21946-21947 |
, |
denotes |
, |
T7715 |
21948-21959 |
NNS |
denotes |
immunoblots |
T7716 |
21960-21964 |
VBD |
denotes |
were |
T7717 |
21965-21972 |
VBN |
denotes |
scanned |
T7718 |
21973-21976 |
CC |
denotes |
and |
T7719 |
21977-21982 |
NNS |
denotes |
gates |
T7720 |
21983-21987 |
VBD |
denotes |
were |
T7721 |
21988-21993 |
VBN |
denotes |
drawn |
T7722 |
21994-22001 |
RB |
denotes |
tightly |
T7723 |
22002-22008 |
IN |
denotes |
around |
T7724 |
22009-22013 |
DT |
denotes |
each |
T7725 |
22014-22018 |
NN |
denotes |
band |
T7726 |
22018-22019 |
. |
denotes |
. |
T7727 |
22020-22030 |
NN |
denotes |
Background |
T7728 |
22031-22037 |
NNS |
denotes |
values |
T7729 |
22038-22042 |
IN |
denotes |
from |
T7730 |
22043-22047 |
DT |
denotes |
each |
T7731 |
22048-22052 |
NN |
denotes |
lane |
T7732 |
22053-22057 |
VBD |
denotes |
were |
T7733 |
22058-22068 |
VBN |
denotes |
subtracted |
T7734 |
22069-22071 |
TO |
denotes |
to |
T7735 |
22072-22081 |
VB |
denotes |
normalize |
T7736 |
22082-22086 |
DT |
denotes |
each |
T7737 |
22087-22098 |
NN |
denotes |
measurement |
T7738 |
22098-22099 |
. |
denotes |
. |
T7739 |
22100-22103 |
DT |
denotes |
The |
T7740 |
22104-22109 |
NNS |
denotes |
bands |
T7741 |
22110-22114 |
VBD |
denotes |
were |
T7742 |
22115-22125 |
VBN |
denotes |
quantified |
T7743 |
22126-22131 |
VBG |
denotes |
using |
T7744 |
22132-22135 |
DT |
denotes |
the |
T7745 |
22136-22144 |
NNPS |
denotes |
Gelworks |
T7746 |
22145-22153 |
NN |
denotes |
software |
T7747 |
22153-22154 |
. |
denotes |
. |
T7748 |
22155-22158 |
DT |
denotes |
All |
T7749 |
22159-22166 |
JJ |
denotes |
Western |
T7750 |
22167-22172 |
NNS |
denotes |
blots |
T7751 |
22173-22177 |
VBD |
denotes |
were |
T7752 |
22178-22185 |
VBN |
denotes |
exposed |
T7753 |
22186-22188 |
TO |
denotes |
to |
T7754 |
22189-22193 |
NN |
denotes |
film |
T7755 |
22194-22197 |
IN |
denotes |
for |
T7756 |
22198-22205 |
VBG |
denotes |
varying |
T7757 |
22206-22213 |
NNS |
denotes |
lengths |
T7758 |
22214-22216 |
IN |
denotes |
of |
T7759 |
22217-22221 |
NN |
denotes |
time |
T7760 |
22221-22222 |
, |
denotes |
, |
T7761 |
22223-22226 |
CC |
denotes |
and |
T7762 |
22227-22231 |
RB |
denotes |
only |
T7763 |
22232-22237 |
NNS |
denotes |
films |
T7764 |
22238-22248 |
VBG |
denotes |
generating |
T7765 |
22249-22262 |
JJ |
denotes |
subsaturating |
T7766 |
22263-22269 |
NNS |
denotes |
levels |
T7767 |
22270-22272 |
IN |
denotes |
of |
T7768 |
22273-22282 |
NN |
denotes |
intensity |
T7769 |
22283-22287 |
VBD |
denotes |
were |
T7770 |
22288-22296 |
VBN |
denotes |
selected |
T7771 |
22297-22300 |
IN |
denotes |
for |
T7772 |
22301-22314 |
JJ |
denotes |
densitometric |
T7773 |
22315-22325 |
NN |
denotes |
evaluation |
T7774 |
22325-22326 |
. |
denotes |
. |
T7934 |
22328-22339 |
NNP |
denotes |
Statistical |
T7935 |
22340-22348 |
NNP |
denotes |
Analysis |
T7936 |
22349-22353 |
NNP |
denotes |
Data |
T7937 |
22354-22358 |
IN |
denotes |
from |
T7938 |
22359-22364 |
CD |
denotes |
three |
T7939 |
22365-22367 |
CC |
denotes |
or |
T7940 |
22368-22372 |
JJR |
denotes |
more |
T7941 |
22373-22384 |
JJ |
denotes |
independent |
T7942 |
22385-22396 |
NNS |
denotes |
experiments |
T7943 |
22397-22400 |
VBP |
denotes |
are |
T7944 |
22401-22410 |
VBN |
denotes |
presented |
T7945 |
22411-22413 |
IN |
denotes |
as |
T7946 |
22414-22417 |
DT |
denotes |
the |
T7947 |
22418-22422 |
JJ |
denotes |
mean |
T7948 |
22422-22423 |
NN |
denotes |
± |
T7949 |
22423-22431 |
NN |
denotes |
standard |
T7950 |
22432-22437 |
NN |
denotes |
error |
T7951 |
22438-22440 |
IN |
denotes |
of |
T7952 |
22441-22444 |
DT |
denotes |
the |
T7953 |
22445-22449 |
NN |
denotes |
mean |
T7954 |
22450-22451 |
-LRB- |
denotes |
( |
T7955 |
22451-22454 |
NNP |
denotes |
SEM |
T7956 |
22454-22455 |
-RRB- |
denotes |
) |
T7957 |
22455-22456 |
, |
denotes |
, |
T7958 |
22457-22463 |
IN |
denotes |
except |
T7959 |
22464-22469 |
WRB |
denotes |
where |
T7960 |
22470-22476 |
VBN |
denotes |
stated |
T7961 |
22477-22480 |
CC |
denotes |
and |
T7962 |
22481-22485 |
VBD |
denotes |
were |
T7963 |
22486-22494 |
VBN |
denotes |
compared |
T7964 |
22495-22500 |
VBG |
denotes |
using |
T7965 |
22501-22509 |
NNP |
denotes |
GraphPad |
T7966 |
22510-22515 |
NNP |
denotes |
Prism |
T7967 |
22516-22517 |
CD |
denotes |
4 |
T7968 |
22518-22519 |
-LRB- |
denotes |
( |
T7969 |
22519-22527 |
NNP |
denotes |
GraphPad |
T7970 |
22528-22536 |
NNP |
denotes |
Software |
T7971 |
22536-22537 |
, |
denotes |
, |
T7972 |
22538-22561 |
NN |
denotes |
http://www.graphpad.com |
T7973 |
22561-22562 |
-RRB- |
denotes |
) |
T7974 |
22562-22563 |
. |
denotes |
. |
T7975 |
22564-22571 |
NNS |
denotes |
Results |
T7976 |
22572-22576 |
VBD |
denotes |
were |
T7977 |
22577-22585 |
JJ |
denotes |
analysed |
T7978 |
22586-22591 |
VBG |
denotes |
using |
T7979 |
22592-22599 |
JJ |
denotes |
one-way |
T7980 |
22600-22605 |
NNP |
denotes |
ANOVA |
T7981 |
22606-22610 |
IN |
denotes |
with |
T7982 |
22611-22623 |
NNP |
denotes |
Newman-Keuls |
T7983 |
22624-22628 |
NN |
denotes |
post |
T7984 |
22629-22633 |
NN |
denotes |
test |
T7985 |
22634-22640 |
IN |
denotes |
except |
T7986 |
22641-22644 |
IN |
denotes |
for |
T7987 |
22645-22648 |
DT |
denotes |
the |
T7988 |
22649-22653 |
NNS |
denotes |
data |
T7989 |
22654-22658 |
IN |
denotes |
from |
T7990 |
22659-22662 |
DT |
denotes |
the |
T7991 |
22663-22665 |
IN |
denotes |
in |
T7992 |
22666-22670 |
NN |
denotes |
vivo |
T7993 |
22671-22678 |
VBD |
denotes |
inhaled |
T7994 |
22679-22681 |
NNP |
denotes |
FP |
T7995 |
22682-22687 |
NN |
denotes |
study |
T7996 |
22687-22688 |
, |
denotes |
, |
T7997 |
22689-22694 |
WDT |
denotes |
which |
T7998 |
22695-22698 |
VBD |
denotes |
was |
T7999 |
22699-22707 |
VBN |
denotes |
analysed |
T8000 |
22708-22710 |
IN |
denotes |
by |
T8001 |
22711-22719 |
NNP |
denotes |
Friedman |
T8002 |
22719-22721 |
POS |
denotes |
's |
T8003 |
22722-22726 |
NN |
denotes |
test |
T8004 |
22727-22731 |
IN |
denotes |
with |
T8005 |
22732-22742 |
JJ |
denotes |
subsequent |
T8006 |
22743-22752 |
NNP |
denotes |
Wilcoxson |
T8007 |
22753-22760 |
VBD |
denotes |
matched |
T8008 |
22761-22765 |
NN |
denotes |
pair |
T8009 |
22766-22772 |
VBD |
denotes |
signed |
T8010 |
22773-22777 |
NN |
denotes |
rank |
T8011 |
22778-22781 |
NN |
denotes |
sum |
T8012 |
22782-22786 |
NN |
denotes |
test |
T8013 |
22786-22787 |
. |
denotes |
. |
T8014 |
22788-22792 |
NNP |
denotes |
Data |
T8015 |
22793-22797 |
IN |
denotes |
from |
T8016 |
22798-22802 |
DT |
denotes |
this |
T8017 |
22803-22811 |
NN |
denotes |
analysis |
T8018 |
22812-22815 |
VBP |
denotes |
are |
T8019 |
22816-22825 |
VBN |
denotes |
presented |
T8020 |
22826-22828 |
IN |
denotes |
as |
T8021 |
22829-22830 |
DT |
denotes |
a |
T8022 |
22831-22847 |
NNS |
denotes |
box-and-whiskers |
T8023 |
22848-22852 |
NN |
denotes |
plot |
T8024 |
22852-22853 |
. |
denotes |
. |
T8025 |
22854-22862 |
NNP |
denotes |
Friedman |
T8026 |
22862-22864 |
POS |
denotes |
's |
T8027 |
22865-22869 |
NN |
denotes |
test |
T8028 |
22870-22873 |
VBD |
denotes |
was |
T8029 |
22874-22878 |
VBN |
denotes |
used |
T8030 |
22879-22881 |
IN |
denotes |
as |
T8031 |
22882-22887 |
CD |
denotes |
three |
T8032 |
22888-22895 |
VBN |
denotes |
matched |
T8033 |
22896-22904 |
NNS |
denotes |
measures |
T8034 |
22905-22909 |
VBD |
denotes |
were |
T8035 |
22910-22918 |
VBN |
denotes |
obtained |
T8036 |
22919-22924 |
VBG |
denotes |
using |
T8037 |
22925-22932 |
NN |
denotes |
placebo |
T8038 |
22932-22933 |
, |
denotes |
, |
T8039 |
22934-22937 |
CD |
denotes |
100 |
T8040 |
22938-22940 |
NN |
denotes |
µg |
T8041 |
22940-22941 |
, |
denotes |
, |
T8042 |
22942-22945 |
CC |
denotes |
and |
T8043 |
22946-22949 |
CD |
denotes |
500 |
T8044 |
22950-22952 |
NN |
denotes |
µg |
T8045 |
22953-22955 |
IN |
denotes |
of |
T8046 |
22956-22963 |
JJ |
denotes |
inhaled |
T8047 |
22964-22966 |
NNP |
denotes |
FP |
T8048 |
22966-22967 |
, |
denotes |
, |
T8049 |
22968-22973 |
WDT |
denotes |
which |
T8050 |
22974-22977 |
VBD |
denotes |
had |
T8051 |
22978-22986 |
JJ |
denotes |
variable |
T8052 |
22987-22995 |
NN |
denotes |
baseline |
T8053 |
22996-23002 |
NNS |
denotes |
levels |
T8054 |
23002-23003 |
. |
denotes |
. |
T8055 |
23004-23006 |
PRP |
denotes |
We |
T8056 |
23007-23010 |
VBD |
denotes |
did |
T8057 |
23011-23014 |
RB |
denotes |
not |
T8058 |
23015-23021 |
VB |
denotes |
assume |
T8059 |
23022-23023 |
DT |
denotes |
a |
T8060 |
23024-23032 |
JJ |
denotes |
Gaussian |
T8061 |
23033-23045 |
NN |
denotes |
distribution |
T8062 |
23046-23048 |
IN |
denotes |
of |
T8063 |
23049-23052 |
DT |
denotes |
the |
T8064 |
23053-23057 |
NNS |
denotes |
data |
T8065 |
23058-23061 |
JJ |
denotes |
due |
T8066 |
23062-23064 |
TO |
denotes |
to |
T8067 |
23065-23068 |
DT |
denotes |
the |
T8068 |
23069-23076 |
JJ |
denotes |
limited |
T8069 |
23077-23084 |
NNS |
denotes |
numbers |
T8070 |
23085-23087 |
IN |
denotes |
of |
T8071 |
23088-23100 |
NNS |
denotes |
participants |
T8072 |
23101-23109 |
VBN |
denotes |
analysed |
T8073 |
23110-23111 |
-LRB- |
denotes |
( |
T8074 |
23111-23116 |
CD |
denotes |
seven |
T8075 |
23116-23117 |
-RRB- |
denotes |
) |
T8076 |
23117-23118 |
. |
denotes |
. |
T8077 |
23118-23121 |
DT |
denotes |
The |
T8078 |
23122-23126 |
NN |
denotes |
null |
T8079 |
23127-23137 |
NN |
denotes |
hypothesis |
T8080 |
23138-23141 |
VBD |
denotes |
was |
T8081 |
23142-23150 |
VBN |
denotes |
rejected |
T8082 |
23151-23153 |
IN |
denotes |
at |
T8083 |
23154-23155 |
NN |
denotes |
p |
T8084 |
23155-23156 |
NN |
denotes |
< |
T8085 |
23156-23160 |
CD |
denotes |
0.05 |
T8086 |
23160-23161 |
. |
denotes |
. |
T8451 |
23172-23175 |
DT |
denotes |
The |
T8452 |
23176-23182 |
NN |
denotes |
Effect |
T8453 |
23183-23185 |
IN |
denotes |
of |
T8454 |
23186-23201 |
NNS |
denotes |
Corticosteroids |
T8455 |
23202-23204 |
IN |
denotes |
on |
T8456 |
23205-23211 |
NNP |
denotes |
GATA-3 |
T8457 |
23212-23219 |
NNP |
denotes |
Nuclear |
T8458 |
23220-23233 |
NNP |
denotes |
Translocation |
T8459 |
23234-23237 |
CC |
denotes |
and |
T8460 |
23238-23242 |
NN |
denotes |
IL-4 |
T8461 |
23243-23247 |
NNP |
denotes |
mRNA |
T8462 |
23248-23263 |
NNP |
denotes |
Corticosteroids |
T8463 |
23264-23267 |
VBP |
denotes |
are |
T8464 |
23268-23277 |
JJ |
denotes |
effective |
T8465 |
23278-23280 |
IN |
denotes |
in |
T8466 |
23281-23291 |
VBG |
denotes |
inhibiting |
T8467 |
23292-23308 |
JJ |
denotes |
GATA-3-regulated |
T8468 |
23309-23313 |
NN |
denotes |
IL-4 |
T8469 |
23314-23318 |
NN |
denotes |
gene |
T8470 |
23319-23329 |
NN |
denotes |
expression |
T8471 |
23330-23332 |
IN |
denotes |
in |
T8472 |
23333-23338 |
NN |
denotes |
vitro |
T8473 |
23339-23342 |
CC |
denotes |
and |
T8474 |
23343-23345 |
IN |
denotes |
in |
T8475 |
23346-23350 |
NN |
denotes |
vivo |
T8476 |
23351-23352 |
NNP |
denotes |
[ |
T8477 |
23352-23354 |
CD |
denotes |
32 |
T8478 |
23354-23355 |
NNP |
denotes |
] |
T8479 |
23355-23356 |
. |
denotes |
. |
T8480 |
23357-23359 |
PRP |
denotes |
We |
T8481 |
23360-23369 |
RB |
denotes |
therefore |
T8482 |
23370-23382 |
VBD |
denotes |
investigated |
T8483 |
23383-23390 |
IN |
denotes |
whether |
T8484 |
23391-23406 |
NNS |
denotes |
corticosteroids |
T8485 |
23407-23413 |
VBP |
denotes |
affect |
T8486 |
23414-23422 |
JJ |
denotes |
anti-CD3 |
T8487 |
23422-23423 |
NN |
denotes |
/ |
T8488 |
23423-23427 |
CD |
denotes |
CD28 |
T8489 |
23428-23438 |
VBD |
denotes |
stimulated |
T8490 |
23439-23446 |
JJ |
denotes |
nuclear |
T8491 |
23447-23453 |
NN |
denotes |
import |
T8492 |
23454-23456 |
IN |
denotes |
of |
T8493 |
23457-23463 |
NN |
denotes |
GATA-3 |
T8494 |
23463-23464 |
. |
denotes |
. |
T8495 |
23465-23476 |
NN |
denotes |
Stimulation |
T8496 |
23477-23479 |
IN |
denotes |
of |
T8497 |
23480-23485 |
NNS |
denotes |
cells |
T8498 |
23486-23490 |
IN |
denotes |
with |
T8499 |
23491-23499 |
JJ |
denotes |
anti-CD3 |
T8500 |
23499-23500 |
NN |
denotes |
/ |
T8501 |
23500-23504 |
CD |
denotes |
CD28 |
T8502 |
23505-23513 |
VBD |
denotes |
resulted |
T8503 |
23514-23516 |
IN |
denotes |
in |
T8504 |
23517-23518 |
DT |
denotes |
a |
T8505 |
23519-23524 |
JJ |
denotes |
rapid |
T8506 |
23525-23544 |
NN |
denotes |
cytoplasmic/nuclear |
T8507 |
23545-23551 |
NN |
denotes |
GATA-3 |
T8508 |
23552-23565 |
NN |
denotes |
translocation |
T8509 |
23566-23567 |
-LRB- |
denotes |
( |
T8510 |
23567-23573 |
NN |
denotes |
Figure |
T8511 |
23574-23576 |
CD |
denotes |
1A |
T8512 |
23576-23577 |
-RRB- |
denotes |
) |
T8513 |
23577-23578 |
, |
denotes |
, |
T8514 |
23579-23589 |
VBG |
denotes |
confirming |
T8515 |
23590-23593 |
PRP$ |
denotes |
our |
T8516 |
23594-23602 |
JJ |
denotes |
previous |
T8517 |
23603-23610 |
NNS |
denotes |
results |
T8518 |
23611-23612 |
NNP |
denotes |
[ |
T8519 |
23612-23614 |
CD |
denotes |
12 |
T8520 |
23614-23615 |
NNP |
denotes |
] |
T8521 |
23615-23616 |
. |
denotes |
. |
T8522 |
23617-23619 |
PRP |
denotes |
We |
T8523 |
23620-23624 |
RB |
denotes |
also |
T8524 |
23625-23634 |
VBD |
denotes |
confirmed |
T8525 |
23635-23636 |
DT |
denotes |
a |
T8526 |
23637-23642 |
JJ |
denotes |
clear |
T8527 |
23643-23653 |
NN |
denotes |
separation |
T8528 |
23654-23656 |
IN |
denotes |
of |
T8529 |
23657-23664 |
JJ |
denotes |
nuclear |
T8530 |
23665-23668 |
CC |
denotes |
and |
T8531 |
23669-23678 |
JJ |
denotes |
cytosolic |
T8532 |
23679-23688 |
NNS |
denotes |
fractions |
T8533 |
23689-23691 |
IN |
denotes |
as |
T8534 |
23692-23701 |
VBN |
denotes |
indicated |
T8535 |
23702-23704 |
IN |
denotes |
by |
T8536 |
23705-23712 |
NN |
denotes |
histone |
T8537 |
23713-23715 |
CD |
denotes |
H1 |
T8538 |
23716-23719 |
CC |
denotes |
and |
T8539 |
23720-23725 |
CD |
denotes |
MEK-1 |
T8540 |
23726-23733 |
NNS |
denotes |
markers |
T8541 |
23734-23735 |
-LRB- |
denotes |
( |
T8542 |
23735-23741 |
NN |
denotes |
Figure |
T8543 |
23742-23744 |
NN |
denotes |
1B |
T8544 |
23744-23745 |
-RRB- |
denotes |
) |
T8545 |
23745-23746 |
. |
denotes |
. |
T8546 |
23747-23750 |
DT |
denotes |
The |
T8547 |
23751-23757 |
JJ |
denotes |
potent |
T8548 |
23758-23765 |
JJ |
denotes |
topical |
T8549 |
23766-23780 |
JJ |
denotes |
corticosteroid |
T8550 |
23781-23783 |
NN |
denotes |
FP |
T8551 |
23784-23790 |
VBD |
denotes |
caused |
T8552 |
23791-23800 |
JJ |
denotes |
sustained |
T8553 |
23801-23805 |
NN |
denotes |
loss |
T8554 |
23806-23808 |
IN |
denotes |
of |
T8555 |
23809-23816 |
JJ |
denotes |
nuclear |
T8556 |
23817-23823 |
JJ |
denotes |
GATA-3 |
T8557 |
23824-23834 |
NN |
denotes |
expression |
T8558 |
23835-23838 |
CC |
denotes |
and |
T8559 |
23839-23850 |
JJ |
denotes |
cytoplasmic |
T8560 |
23851-23860 |
NN |
denotes |
retention |
T8561 |
23861-23863 |
IN |
denotes |
of |
T8562 |
23864-23870 |
NN |
denotes |
GATA-3 |
T8563 |
23871-23873 |
IN |
denotes |
at |
T8564 |
23874-23888 |
NNS |
denotes |
concentrations |
T8565 |
23889-23896 |
VBG |
denotes |
ranging |
T8566 |
23897-23901 |
IN |
denotes |
from |
T8567 |
23902-23904 |
CD |
denotes |
10 |
T8568 |
23904-23905 |
CD |
denotes |
− |
T8569 |
23905-23907 |
CD |
denotes |
12 |
T8570 |
23908-23910 |
TO |
denotes |
to |
T8571 |
23911-23913 |
CD |
denotes |
10 |
T8572 |
23913-23914 |
CD |
denotes |
− |
T8573 |
23914-23915 |
CD |
denotes |
8 |
T8574 |
23916-23917 |
NNP |
denotes |
M |
T8575 |
23917-23918 |
, |
denotes |
, |
T8576 |
23919-23924 |
WDT |
denotes |
which |
T8577 |
23925-23930 |
VBP |
denotes |
cover |
T8578 |
23931-23934 |
DT |
denotes |
the |
T8579 |
23935-23946 |
JJ |
denotes |
therapeutic |
T8580 |
23947-23952 |
NN |
denotes |
range |
T8581 |
23953-23954 |
NNP |
denotes |
[ |
T8582 |
23954-23956 |
CD |
denotes |
37 |
T8583 |
23956-23957 |
NNP |
denotes |
] |
T8584 |
23957-23958 |
. |
denotes |
. |
T8585 |
23959-23963 |
DT |
denotes |
This |
T8586 |
23964-23970 |
NN |
denotes |
effect |
T8587 |
23971-23974 |
VBD |
denotes |
was |
T8588 |
23975-23988 |
NN |
denotes |
concentration |
T8589 |
23988-23989 |
: |
denotes |
- |
T8590 |
23990-23993 |
CC |
denotes |
and |
T8591 |
23994-24008 |
JJ |
denotes |
time-dependent |
T8592 |
24008-24009 |
, |
denotes |
, |
T8593 |
24010-24014 |
IN |
denotes |
with |
T8594 |
24015-24016 |
DT |
denotes |
a |
T8595 |
24017-24021 |
JJ |
denotes |
peak |
T8596 |
24022-24028 |
NN |
denotes |
effect |
T8597 |
24029-24031 |
IN |
denotes |
of |
T8598 |
24032-24041 |
JJ |
denotes |
11.6-fold |
T8599 |
24042-24044 |
IN |
denotes |
at |
T8600 |
24045-24047 |
CD |
denotes |
30 |
T8601 |
24048-24051 |
NN |
denotes |
min |
T8602 |
24052-24054 |
IN |
denotes |
at |
T8603 |
24055-24056 |
DT |
denotes |
a |
T8604 |
24057-24070 |
NN |
denotes |
concentration |
T8605 |
24071-24073 |
IN |
denotes |
of |
T8606 |
24074-24076 |
CD |
denotes |
10 |
T8607 |
24076-24077 |
NN |
denotes |
− |
T8608 |
24077-24078 |
CD |
denotes |
8 |
T8609 |
24079-24080 |
NNP |
denotes |
M |
T8610 |
24081-24082 |
-LRB- |
denotes |
( |
T8611 |
24082-24088 |
NNP |
denotes |
Figure |
T8612 |
24089-24091 |
NNP |
denotes |
1C |
T8613 |
24091-24092 |
-RRB- |
denotes |
) |
T8614 |
24093-24096 |
CC |
denotes |
and |
T8615 |
24097-24100 |
VBD |
denotes |
was |
T8616 |
24101-24111 |
VBN |
denotes |
associated |
T8617 |
24112-24116 |
IN |
denotes |
with |
T8618 |
24117-24123 |
JJ |
denotes |
marked |
T8619 |
24124-24134 |
NNS |
denotes |
reductions |
T8620 |
24135-24137 |
IN |
denotes |
in |
T8621 |
24138-24146 |
JJ |
denotes |
anti-CD3 |
T8622 |
24146-24147 |
NN |
denotes |
/ |
T8623 |
24147-24151 |
CD |
denotes |
CD28 |
T8624 |
24152-24162 |
VBD |
denotes |
stimulated |
T8625 |
24163-24167 |
NN |
denotes |
IL-4 |
T8626 |
24168-24171 |
CC |
denotes |
and |
T8627 |
24172-24176 |
NN |
denotes |
IL-5 |
T8628 |
24177-24181 |
NNP |
denotes |
mRNA |
T8629 |
24182-24192 |
NN |
denotes |
expression |
T8630 |
24193-24194 |
-LRB- |
denotes |
( |
T8631 |
24194-24200 |
NN |
denotes |
Figure |
T8632 |
24201-24203 |
CD |
denotes |
1D |
T8633 |
24203-24204 |
-RRB- |
denotes |
) |
T8634 |
24205-24208 |
CC |
denotes |
and |
T8635 |
24209-24210 |
DT |
denotes |
a |
T8636 |
24211-24215 |
NN |
denotes |
loss |
T8637 |
24216-24218 |
IN |
denotes |
of |
T8638 |
24219-24225 |
JJ |
denotes |
GATA-3 |
T8639 |
24226-24233 |
JJ |
denotes |
binding |
T8640 |
24234-24236 |
TO |
denotes |
to |
T8641 |
24237-24240 |
DT |
denotes |
the |
T8642 |
24241-24247 |
JJ |
denotes |
native |
T8643 |
24248-24252 |
NN |
denotes |
IL-5 |
T8644 |
24253-24261 |
NN |
denotes |
promoter |
T8645 |
24262-24263 |
-LRB- |
denotes |
( |
T8646 |
24263-24269 |
NN |
denotes |
Figure |
T8647 |
24270-24272 |
CD |
denotes |
1E |
T8648 |
24272-24273 |
-RRB- |
denotes |
) |
T8649 |
24273-24274 |
. |
denotes |
. |
T16315 |
24319-24330 |
NNP |
denotes |
Fluticasone |
T16316 |
24331-24341 |
JJ |
denotes |
propionate |
T16317 |
24342-24356 |
NNS |
denotes |
down-regulates |
T16318 |
24357-24360 |
JJ |
denotes |
Th2 |
T16319 |
24361-24369 |
NN |
denotes |
cytokine |
T16320 |
24370-24374 |
NN |
denotes |
gene |
T16321 |
24375-24385 |
NN |
denotes |
expression |
T16322 |
24386-24389 |
CC |
denotes |
and |
T16323 |
24390-24398 |
NNS |
denotes |
inhibits |
T16324 |
24399-24405 |
JJ |
denotes |
GATA-3 |
T16325 |
24406-24413 |
JJ |
denotes |
nuclear |
T16326 |
24414-24420 |
NN |
denotes |
import |
T16327 |
24420-24421 |
. |
denotes |
. |
T16328 |
24422-24423 |
-LRB- |
denotes |
( |
T16329 |
24423-24424 |
NNP |
denotes |
A |
T16330 |
24424-24425 |
-RRB- |
denotes |
) |
T16331 |
24426-24434 |
JJ |
denotes |
Anti-CD3 |
T16332 |
24434-24435 |
NN |
denotes |
/ |
T16333 |
24435-24439 |
CD |
denotes |
CD28 |
T16334 |
24440-24449 |
NN |
denotes |
treatment |
T16335 |
24450-24452 |
IN |
denotes |
of |
T16336 |
24453-24459 |
JJ |
denotes |
HuT-78 |
T16337 |
24460-24465 |
NNS |
denotes |
cells |
T16338 |
24466-24473 |
NNS |
denotes |
results |
T16339 |
24474-24476 |
IN |
denotes |
in |
T16340 |
24477-24490 |
NN |
denotes |
translocation |
T16341 |
24491-24493 |
IN |
denotes |
of |
T16342 |
24494-24500 |
NN |
denotes |
GATA-3 |
T16343 |
24501-24505 |
IN |
denotes |
from |
T16344 |
24506-24509 |
DT |
denotes |
the |
T16345 |
24510-24519 |
NN |
denotes |
cytoplasm |
T16346 |
24520-24522 |
TO |
denotes |
to |
T16347 |
24523-24526 |
DT |
denotes |
the |
T16348 |
24527-24534 |
NN |
denotes |
nucleus |
T16349 |
24535-24541 |
IN |
denotes |
within |
T16350 |
24542-24544 |
CD |
denotes |
30 |
T16351 |
24545-24548 |
NN |
denotes |
min |
T16352 |
24548-24549 |
. |
denotes |
. |
T16353 |
24550-24551 |
-LRB- |
denotes |
( |
T16354 |
24551-24552 |
NNP |
denotes |
B |
T16355 |
24552-24553 |
-RRB- |
denotes |
) |
T16356 |
24554-24561 |
NNP |
denotes |
Histone |
T16357 |
24562-24564 |
NNP |
denotes |
H1 |
T16358 |
24565-24568 |
CC |
denotes |
and |
T16359 |
24569-24574 |
NNP |
denotes |
MEK-1 |
T16360 |
24575-24579 |
VBD |
denotes |
were |
T16361 |
24580-24584 |
VBN |
denotes |
used |
T16362 |
24585-24587 |
TO |
denotes |
to |
T16363 |
24588-24595 |
VB |
denotes |
confirm |
T16364 |
24596-24604 |
JJ |
denotes |
distinct |
T16365 |
24605-24615 |
NN |
denotes |
separation |
T16366 |
24616-24618 |
IN |
denotes |
of |
T16367 |
24619-24630 |
JJ |
denotes |
cytoplasmic |
T16368 |
24631-24634 |
CC |
denotes |
and |
T16369 |
24635-24642 |
JJ |
denotes |
nuclear |
T16370 |
24643-24651 |
NNS |
denotes |
extracts |
T16371 |
24652-24654 |
IN |
denotes |
in |
T16372 |
24655-24660 |
CD |
denotes |
three |
T16373 |
24661-24669 |
JJ |
denotes |
separate |
T16374 |
24670-24681 |
NNS |
denotes |
experiments |
T16375 |
24681-24682 |
. |
denotes |
. |
T16376 |
24683-24684 |
-LRB- |
denotes |
( |
T16377 |
24684-24685 |
$ |
denotes |
C |
T16378 |
24685-24686 |
-RRB- |
denotes |
) |
T16379 |
24687-24694 |
JJ |
denotes |
Western |
T16380 |
24695-24699 |
NN |
denotes |
blot |
T16381 |
24700-24708 |
NN |
denotes |
analysis |
T16382 |
24709-24711 |
IN |
denotes |
of |
T16383 |
24712-24722 |
JJ |
denotes |
FP-treated |
T16384 |
24723-24729 |
JJ |
denotes |
HuT-78 |
T16385 |
24730-24735 |
NNS |
denotes |
cells |
T16386 |
24736-24748 |
VBD |
denotes |
demonstrated |
T16387 |
24749-24757 |
VBN |
denotes |
impaired |
T16388 |
24758-24765 |
JJ |
denotes |
nuclear |
T16389 |
24766-24778 |
NN |
denotes |
localization |
T16390 |
24779-24781 |
IN |
denotes |
of |
T16391 |
24782-24788 |
JJ |
denotes |
GATA-3 |
T16392 |
24789-24796 |
VBN |
denotes |
induced |
T16393 |
24797-24799 |
IN |
denotes |
by |
T16394 |
24800-24808 |
JJ |
denotes |
anti-CD3 |
T16395 |
24808-24809 |
NN |
denotes |
/ |
T16396 |
24809-24813 |
CD |
denotes |
CD28 |
T16397 |
24814-24828 |
NN |
denotes |
co-stimulation |
T16398 |
24829-24831 |
IN |
denotes |
in |
T16399 |
24832-24833 |
DT |
denotes |
a |
T16400 |
24834-24838 |
NN |
denotes |
time |
T16401 |
24838-24839 |
: |
denotes |
- |
T16402 |
24840-24841 |
-LRB- |
denotes |
( |
T16403 |
24841-24843 |
IN |
denotes |
at |
T16404 |
24844-24846 |
CD |
denotes |
10 |
T16405 |
24846-24847 |
NN |
denotes |
− |
T16406 |
24847-24848 |
CD |
denotes |
8 |
T16407 |
24849-24850 |
NNP |
denotes |
M |
T16408 |
24851-24853 |
NNP |
denotes |
FP |
T16409 |
24853-24854 |
-RRB- |
denotes |
) |
T16410 |
24855-24858 |
CC |
denotes |
and |
T16411 |
24859-24872 |
NN |
denotes |
concentration |
T16412 |
24872-24873 |
: |
denotes |
- |
T16413 |
24874-24875 |
-LRB- |
denotes |
( |
T16414 |
24875-24877 |
IN |
denotes |
at |
T16415 |
24878-24880 |
CD |
denotes |
60 |
T16416 |
24881-24884 |
NN |
denotes |
min |
T16417 |
24885-24890 |
IN |
denotes |
after |
T16418 |
24891-24902 |
NN |
denotes |
stimulation |
T16419 |
24902-24903 |
-RRB- |
denotes |
) |
T16420 |
24904-24913 |
JJ |
denotes |
dependent |
T16421 |
24914-24920 |
NN |
denotes |
manner |
T16422 |
24920-24921 |
. |
denotes |
. |
T16423 |
24922-24927 |
NNS |
denotes |
Cells |
T16424 |
24928-24932 |
VBD |
denotes |
were |
T16425 |
24933-24943 |
VBN |
denotes |
pretreated |
T16426 |
24944-24948 |
IN |
denotes |
with |
T16427 |
24949-24951 |
NNP |
denotes |
FP |
T16428 |
24952-24955 |
IN |
denotes |
for |
T16429 |
24956-24958 |
CD |
denotes |
30 |
T16430 |
24959-24962 |
NN |
denotes |
min |
T16431 |
24963-24968 |
RB |
denotes |
prior |
T16432 |
24969-24971 |
TO |
denotes |
to |
T16433 |
24972-24983 |
NN |
denotes |
stimulation |
T16434 |
24983-24984 |
. |
denotes |
. |
T16435 |
24985-24989 |
CD |
denotes |
MEK1 |
T16436 |
24990-24993 |
CC |
denotes |
and |
T16437 |
24994-25001 |
VB |
denotes |
histone |
T16438 |
25002-25004 |
CD |
denotes |
H1 |
T16439 |
25005-25009 |
VBD |
denotes |
were |
T16440 |
25010-25014 |
VBN |
denotes |
used |
T16441 |
25015-25017 |
TO |
denotes |
to |
T16442 |
25018-25029 |
VB |
denotes |
demonstrate |
T16443 |
25030-25035 |
JJ |
denotes |
equal |
T16444 |
25036-25047 |
JJ |
denotes |
cytoplasmic |
T16445 |
25048-25051 |
CC |
denotes |
and |
T16446 |
25052-25059 |
JJ |
denotes |
nuclear |
T16447 |
25060-25067 |
VBG |
denotes |
loading |
T16448 |
25068-25080 |
RB |
denotes |
respectively |
T16449 |
25080-25081 |
. |
denotes |
. |
T16450 |
25082-25089 |
NNS |
denotes |
Results |
T16451 |
25090-25093 |
VBP |
denotes |
are |
T16452 |
25094-25103 |
VBN |
denotes |
presented |
T16453 |
25104-25115 |
RB |
denotes |
graphically |
T16454 |
25116-25121 |
IN |
denotes |
below |
T16455 |
25122-25124 |
IN |
denotes |
as |
T16456 |
25125-25129 |
JJ |
denotes |
mean |
T16457 |
25129-25130 |
NN |
denotes |
± |
T16458 |
25130-25133 |
NNP |
denotes |
SEM |
T16459 |
25134-25136 |
IN |
denotes |
of |
T16460 |
25137-25139 |
IN |
denotes |
at |
T16461 |
25140-25145 |
JJS |
denotes |
least |
T16462 |
25146-25151 |
CD |
denotes |
three |
T16463 |
25152-25163 |
JJ |
denotes |
independent |
T16464 |
25164-25175 |
NNS |
denotes |
experiments |
T16465 |
25175-25176 |
. |
denotes |
. |
T16466 |
25177-25180 |
FW |
denotes |
*** |
T16467 |
25181-25182 |
FW |
denotes |
p |
T16521 |
25181-25182 |
FW |
denotes |
p |
T17324 |
25181-25182 |
FW |
denotes |
p |
T18004 |
25181-25182 |
FW |
denotes |
p |
T16468 |
25182-25183 |
FW |
denotes |
< |
T16522 |
25182-25183 |
FW |
denotes |
< |
T17325 |
25182-25183 |
FW |
denotes |
< |
T18005 |
25182-25183 |
FW |
denotes |
< |
T16469 |
25183-25188 |
CD |
denotes |
0.001 |
T16523 |
25183-25188 |
CD |
denotes |
0.001 |
T17326 |
25183-25188 |
CD |
denotes |
0.001 |
T18006 |
25183-25188 |
CD |
denotes |
0.001 |
T16470 |
25189-25197 |
VBN |
denotes |
compared |
T16524 |
25189-25197 |
VBN |
denotes |
compared |
T17327 |
25189-25197 |
VBN |
denotes |
compared |
T18007 |
25189-25197 |
VBN |
denotes |
compared |
T16471 |
25198-25200 |
TO |
denotes |
to |
T16525 |
25198-25200 |
TO |
denotes |
to |
T17328 |
25198-25200 |
TO |
denotes |
to |
T18008 |
25198-25200 |
TO |
denotes |
to |
T16472 |
25201-25202 |
VB |
denotes |
t |
T16473 |
25203-25204 |
SYM |
denotes |
= |
T16474 |
25205-25206 |
CD |
denotes |
0 |
T16475 |
25206-25207 |
. |
denotes |
. |
T16476 |
25208-25209 |
-LRB- |
denotes |
( |
T16477 |
25209-25210 |
NNP |
denotes |
D |
T16478 |
25210-25211 |
-RRB- |
denotes |
) |
T16479 |
25212-25218 |
NNP |
denotes |
RT-PCR |
T16480 |
25219-25226 |
VBG |
denotes |
showing |
T16481 |
25227-25231 |
IN |
denotes |
that |
T16482 |
25232-25234 |
NNP |
denotes |
FP |
T16483 |
25235-25243 |
VBZ |
denotes |
inhibits |
T16484 |
25244-25248 |
NN |
denotes |
IL-4 |
T16485 |
25249-25252 |
CC |
denotes |
and |
T16486 |
25253-25257 |
NN |
denotes |
IL-5 |
T16487 |
25258-25262 |
NNP |
denotes |
mRNA |
T16488 |
25263-25273 |
NN |
denotes |
expression |
T16489 |
25274-25276 |
IN |
denotes |
in |
T16490 |
25277-25298 |
JJ |
denotes |
CD3/CD28-costimulated |
T16491 |
25299-25304 |
NNS |
denotes |
cells |
T16492 |
25304-25305 |
. |
denotes |
. |
T16493 |
25306-25311 |
NNP |
denotes |
GAPDH |
T16494 |
25312-25315 |
VBD |
denotes |
was |
T16495 |
25316-25320 |
VBN |
denotes |
used |
T16496 |
25321-25323 |
IN |
denotes |
as |
T16497 |
25324-25325 |
DT |
denotes |
a |
T16498 |
25326-25333 |
VBG |
denotes |
loading |
T16499 |
25334-25341 |
NN |
denotes |
control |
T16500 |
25341-25342 |
. |
denotes |
. |
T16501 |
25343-25348 |
JJR |
denotes |
Lower |
T16502 |
25349-25355 |
NNS |
denotes |
panels |
T16503 |
25356-25360 |
VBP |
denotes |
show |
T16504 |
25361-25370 |
JJ |
denotes |
graphical |
T16505 |
25371-25379 |
NN |
denotes |
analysis |
T16506 |
25380-25382 |
IN |
denotes |
of |
T16507 |
25383-25390 |
NNS |
denotes |
results |
T16508 |
25391-25400 |
VBN |
denotes |
presented |
T16509 |
25401-25403 |
IN |
denotes |
as |
T16510 |
25404-25408 |
JJ |
denotes |
mean |
T16511 |
25408-25409 |
NN |
denotes |
± |
T16512 |
25409-25412 |
NNP |
denotes |
SEM |
T16513 |
25413-25415 |
IN |
denotes |
of |
T16514 |
25416-25418 |
IN |
denotes |
at |
T16515 |
25419-25424 |
JJS |
denotes |
least |
T16516 |
25425-25430 |
CD |
denotes |
three |
T16517 |
25431-25442 |
JJ |
denotes |
independent |
T16518 |
25443-25454 |
NNS |
denotes |
experiments |
T16519 |
25454-25455 |
. |
denotes |
. |
T16520 |
25456-25459 |
FW |
denotes |
### |
T16526 |
25480-25487 |
VB |
denotes |
control |
T17329 |
25480-25487 |
VB |
denotes |
control |
T18009 |
25480-25487 |
VB |
denotes |
control |
T16527 |
25487-25488 |
, |
denotes |
, |
T17330 |
25487-25488 |
, |
denotes |
, |
T18010 |
25487-25488 |
, |
denotes |
, |
T16528 |
25489-25492 |
FW |
denotes |
*** |
T17331 |
25489-25492 |
FW |
denotes |
*** |
T18011 |
25489-25492 |
FW |
denotes |
*** |
T16529 |
25492-25493 |
FW |
denotes |
p |
T17332 |
25492-25493 |
FW |
denotes |
p |
T18012 |
25492-25493 |
FW |
denotes |
p |
T18994 |
25492-25493 |
FW |
denotes |
p |
T16530 |
25493-25494 |
FW |
denotes |
< |
T17333 |
25493-25494 |
FW |
denotes |
< |
T18013 |
25493-25494 |
FW |
denotes |
< |
T18995 |
25493-25494 |
FW |
denotes |
< |
T16531 |
25494-25499 |
CD |
denotes |
0.001 |
T17334 |
25494-25499 |
CD |
denotes |
0.001 |
T18014 |
25494-25499 |
CD |
denotes |
0.001 |
T18996 |
25494-25499 |
CD |
denotes |
0.001 |
T16532 |
25500-25508 |
VBN |
denotes |
compared |
T17335 |
25500-25508 |
VBN |
denotes |
compared |
T18015 |
25500-25508 |
VBN |
denotes |
compared |
T18997 |
25500-25508 |
VBN |
denotes |
compared |
T16533 |
25509-25511 |
TO |
denotes |
to |
T17336 |
25509-25511 |
TO |
denotes |
to |
T18016 |
25509-25511 |
TO |
denotes |
to |
T18998 |
25509-25511 |
TO |
denotes |
to |
T16534 |
25512-25520 |
JJ |
denotes |
anti-CD3 |
T18999 |
25512-25520 |
JJ |
denotes |
anti-CD3 |
T16535 |
25520-25521 |
NN |
denotes |
/ |
T19000 |
25520-25521 |
NN |
denotes |
/ |
T16536 |
25521-25525 |
CD |
denotes |
CD28 |
T19001 |
25521-25525 |
CD |
denotes |
CD28 |
T16537 |
25526-25536 |
VBN |
denotes |
stimulated |
T19002 |
25526-25536 |
VBD |
denotes |
stimulated |
T16538 |
25536-25537 |
. |
denotes |
. |
T16539 |
25538-25539 |
-LRB- |
denotes |
( |
T16540 |
25539-25540 |
NNP |
denotes |
E |
T16541 |
25540-25541 |
-RRB- |
denotes |
) |
T16542 |
25542-25544 |
NNP |
denotes |
FP |
T16543 |
25545-25546 |
-LRB- |
denotes |
( |
T16544 |
25546-25548 |
CD |
denotes |
10 |
T16545 |
25549-25551 |
NNP |
denotes |
nM |
T16546 |
25551-25552 |
-RRB- |
denotes |
) |
T16547 |
25553-25560 |
VBZ |
denotes |
reduces |
T16548 |
25561-25564 |
DT |
denotes |
the |
T16549 |
25565-25572 |
NN |
denotes |
ability |
T16550 |
25573-25575 |
IN |
denotes |
of |
T16551 |
25576-25584 |
JJ |
denotes |
anti-CD3 |
T16552 |
25584-25585 |
NN |
denotes |
/ |
T16553 |
25585-25600 |
JJ |
denotes |
CD28-stimulated |
T16554 |
25601-25607 |
NN |
denotes |
GATA-3 |
T16555 |
25608-25610 |
TO |
denotes |
to |
T16556 |
25611-25620 |
VB |
denotes |
associate |
T16557 |
25621-25625 |
IN |
denotes |
with |
T16558 |
25626-25629 |
DT |
denotes |
the |
T16559 |
25630-25636 |
JJ |
denotes |
native |
T16560 |
25637-25641 |
NN |
denotes |
IL-5 |
T16561 |
25642-25650 |
NN |
denotes |
promoter |
T16562 |
25651-25653 |
CD |
denotes |
60 |
T16563 |
25654-25657 |
NN |
denotes |
min |
T16564 |
25658-25663 |
IN |
denotes |
after |
T16565 |
25664-25675 |
NN |
denotes |
stimulation |
T16566 |
25675-25676 |
. |
denotes |
. |
T16567 |
25677-25681 |
NNS |
denotes |
Data |
T16568 |
25682-25685 |
VBP |
denotes |
are |
T16569 |
25686-25690 |
RB |
denotes |
also |
T16570 |
25691-25696 |
VBN |
denotes |
shown |
T16571 |
25697-25708 |
RB |
denotes |
graphically |
T16572 |
25709-25711 |
IN |
denotes |
as |
T16573 |
25712-25716 |
JJ |
denotes |
mean |
T16574 |
25716-25717 |
NN |
denotes |
± |
T16575 |
25717-25720 |
NNP |
denotes |
SEM |
T16576 |
25721-25723 |
IN |
denotes |
of |
T16577 |
25724-25729 |
CD |
denotes |
three |
T16578 |
25730-25741 |
JJ |
denotes |
independent |
T16579 |
25742-25753 |
NNS |
denotes |
experiments |
T16580 |
25753-25754 |
. |
denotes |
. |
T16581 |
25755-25758 |
DT |
denotes |
All |
T16582 |
25759-25763 |
NNS |
denotes |
data |
T16583 |
25764-25768 |
VBD |
denotes |
were |
T16584 |
25769-25777 |
VBN |
denotes |
analysed |
T16585 |
25778-25780 |
IN |
denotes |
by |
T16586 |
25781-25786 |
NNP |
denotes |
ANOVA |
T16587 |
25787-25795 |
VBD |
denotes |
followed |
T16588 |
25796-25798 |
IN |
denotes |
by |
T16589 |
25799-25811 |
NNP |
denotes |
Newman-Keuls |
T16590 |
25812-25821 |
JJS |
denotes |
post-test |
T16591 |
25821-25822 |
. |
denotes |
. |
T9109 |
25824-25840 |
NNP |
denotes |
Ligand-Activated |
T9110 |
25841-25843 |
NNP |
denotes |
GR |
T9111 |
25844-25852 |
VBZ |
denotes |
Competes |
T9112 |
25853-25857 |
IN |
denotes |
with |
T9113 |
25858-25864 |
NNP |
denotes |
GATA-3 |
T9114 |
25865-25868 |
IN |
denotes |
for |
T9115 |
25869-25879 |
NNP |
denotes |
Importin-α |
T9116 |
25880-25882 |
PRP |
denotes |
We |
T9117 |
25883-25892 |
VBD |
denotes |
confirmed |
T9118 |
25893-25896 |
CC |
denotes |
and |
T9119 |
25897-25905 |
VBD |
denotes |
extended |
T9120 |
25906-25914 |
JJ |
denotes |
previous |
T9121 |
25915-25919 |
NNS |
denotes |
data |
T9122 |
25920-25921 |
NNP |
denotes |
[ |
T9123 |
25921-25923 |
CD |
denotes |
20 |
T9124 |
25923-25924 |
NNP |
denotes |
] |
T9125 |
25925-25927 |
TO |
denotes |
to |
T9126 |
25928-25932 |
VB |
denotes |
show |
T9127 |
25933-25937 |
IN |
denotes |
that |
T9128 |
25938-25954 |
JJ |
denotes |
ligand-activated |
T9129 |
25955-25957 |
NNP |
denotes |
GR |
T9130 |
25958-25960 |
RB |
denotes |
as |
T9131 |
25961-25965 |
RB |
denotes |
well |
T9132 |
25966-25968 |
IN |
denotes |
as |
T9133 |
25969-25975 |
JJ |
denotes |
GATA-3 |
T9134 |
25976-25980 |
NNS |
denotes |
uses |
T9135 |
25981-25991 |
JJ |
denotes |
importin-α |
T9136 |
25992-25995 |
IN |
denotes |
for |
T9137 |
25996-25999 |
PRP$ |
denotes |
its |
T9138 |
26000-26007 |
JJ |
denotes |
nuclear |
T9139 |
26008-26014 |
NN |
denotes |
import |
T9140 |
26015-26016 |
-LRB- |
denotes |
( |
T9141 |
26016-26022 |
NN |
denotes |
Figure |
T9142 |
26023-26025 |
CD |
denotes |
2A |
T9143 |
26026-26029 |
CC |
denotes |
and |
T9144 |
26030-26032 |
CD |
denotes |
2B |
T9145 |
26032-26033 |
-RRB- |
denotes |
) |
T9146 |
26033-26034 |
. |
denotes |
. |
T9147 |
26035-26039 |
DT |
denotes |
This |
T9148 |
26040-26051 |
NN |
denotes |
interaction |
T9149 |
26052-26059 |
IN |
denotes |
between |
T9150 |
26060-26062 |
NNP |
denotes |
GR |
T9151 |
26063-26066 |
CC |
denotes |
and |
T9152 |
26067-26077 |
NNP |
denotes |
importin-α |
T9153 |
26078-26081 |
VBD |
denotes |
was |
T9154 |
26082-26093 |
JJ |
denotes |
significant |
T9155 |
26094-26096 |
IN |
denotes |
at |
T9156 |
26097-26111 |
NNS |
denotes |
concentrations |
T9157 |
26112-26114 |
RB |
denotes |
as |
T9158 |
26115-26118 |
JJ |
denotes |
low |
T9159 |
26119-26121 |
IN |
denotes |
as |
T9160 |
26122-26124 |
CD |
denotes |
10 |
T9161 |
26124-26125 |
CD |
denotes |
− |
T9162 |
26125-26127 |
CD |
denotes |
12 |
T9163 |
26128-26129 |
NNP |
denotes |
M |
T9164 |
26130-26133 |
CC |
denotes |
and |
T9165 |
26134-26137 |
VBD |
denotes |
was |
T9166 |
26138-26145 |
JJ |
denotes |
maximal |
T9167 |
26146-26150 |
IN |
denotes |
with |
T9168 |
26151-26153 |
CD |
denotes |
10 |
T9169 |
26153-26154 |
NN |
denotes |
− |
T9170 |
26154-26155 |
CD |
denotes |
8 |
T9171 |
26156-26157 |
NNP |
denotes |
M |
T9172 |
26158-26160 |
NNP |
denotes |
FP |
T9173 |
26160-26161 |
. |
denotes |
. |
T9174 |
26162-26172 |
JJ |
denotes |
Subsequent |
T9175 |
26173-26175 |
NNP |
denotes |
GR |
T9176 |
26176-26183 |
JJ |
denotes |
nuclear |
T9177 |
26184-26197 |
NN |
denotes |
translocation |
T9178 |
26198-26201 |
VBD |
denotes |
was |
T9179 |
26202-26207 |
JJ |
denotes |
rapid |
T9180 |
26208-26211 |
CC |
denotes |
and |
T9181 |
26212-26221 |
VBD |
denotes |
sustained |
T9182 |
26222-26224 |
IN |
denotes |
at |
T9183 |
26225-26236 |
JJ |
denotes |
significant |
T9184 |
26237-26243 |
NNS |
denotes |
levels |
T9185 |
26244-26247 |
IN |
denotes |
for |
T9186 |
26248-26250 |
IN |
denotes |
at |
T9187 |
26251-26256 |
JJS |
denotes |
least |
T9188 |
26257-26259 |
CD |
denotes |
14 |
T9189 |
26260-26261 |
NN |
denotes |
h |
T9190 |
26262-26263 |
-LRB- |
denotes |
( |
T9191 |
26263-26269 |
NN |
denotes |
Figure |
T9192 |
26270-26272 |
NN |
denotes |
2B |
T9193 |
26272-26273 |
-RRB- |
denotes |
) |
T9194 |
26273-26274 |
. |
denotes |
. |
T9195 |
26275-26280 |
VBG |
denotes |
Using |
T9196 |
26281-26291 |
JJ |
denotes |
IP-Western |
T9197 |
26292-26300 |
VBG |
denotes |
blotting |
T9198 |
26301-26303 |
PRP |
denotes |
we |
T9199 |
26304-26310 |
VBD |
denotes |
showed |
T9200 |
26311-26315 |
IN |
denotes |
that |
T9201 |
26316-26318 |
NNP |
denotes |
FP |
T9202 |
26319-26321 |
IN |
denotes |
at |
T9203 |
26322-26324 |
CD |
denotes |
10 |
T9204 |
26324-26325 |
CD |
denotes |
− |
T9205 |
26325-26327 |
CD |
denotes |
12 |
T9206 |
26328-26330 |
CD |
denotes |
10 |
T9207 |
26330-26331 |
NN |
denotes |
− |
T9208 |
26331-26332 |
CD |
denotes |
8 |
T9209 |
26333-26334 |
NNP |
denotes |
M |
T9210 |
26335-26344 |
VBD |
denotes |
decreased |
T9211 |
26345-26348 |
DT |
denotes |
the |
T9212 |
26349-26360 |
NN |
denotes |
association |
T9213 |
26361-26368 |
IN |
denotes |
between |
T9214 |
26369-26375 |
NNP |
denotes |
GATA-3 |
T9215 |
26376-26379 |
CC |
denotes |
and |
T9216 |
26380-26390 |
JJ |
denotes |
importin-α |
T9217 |
26391-26398 |
VBN |
denotes |
induced |
T9218 |
26399-26401 |
IN |
denotes |
by |
T9219 |
26402-26410 |
JJ |
denotes |
anti-CD3 |
T9220 |
26410-26411 |
NN |
denotes |
/ |
T9221 |
26411-26415 |
CD |
denotes |
CD28 |
T9222 |
26416-26427 |
NN |
denotes |
stimulation |
T9223 |
26428-26430 |
IN |
denotes |
in |
T9224 |
26431-26432 |
DT |
denotes |
a |
T9225 |
26433-26456 |
JJ |
denotes |
concentration-dependent |
T9226 |
26457-26463 |
NN |
denotes |
manner |
T9227 |
26464-26465 |
-LRB- |
denotes |
( |
T9228 |
26465-26471 |
NN |
denotes |
Figure |
T9229 |
26472-26474 |
CD |
denotes |
2C |
T9230 |
26474-26475 |
-RRB- |
denotes |
) |
T9231 |
26475-26476 |
. |
denotes |
. |
T9232 |
26477-26479 |
IN |
denotes |
In |
T9233 |
26480-26488 |
NN |
denotes |
addition |
T9234 |
26488-26489 |
, |
denotes |
, |
T9235 |
26490-26495 |
VBG |
denotes |
using |
T9236 |
26496-26508 |
JJ |
denotes |
GFP-labelled |
T9237 |
26509-26515 |
NN |
denotes |
GATA-3 |
T9238 |
26516-26519 |
CC |
denotes |
and |
T9239 |
26520-26528 |
JJ |
denotes |
confocal |
T9240 |
26529-26539 |
NN |
denotes |
microscopy |
T9241 |
26540-26542 |
PRP |
denotes |
we |
T9242 |
26543-26555 |
VBD |
denotes |
demonstrated |
T9243 |
26556-26560 |
IN |
denotes |
that |
T9244 |
26561-26567 |
JJ |
denotes |
GATA-3 |
T9245 |
26568-26575 |
JJ |
denotes |
nuclear |
T9246 |
26576-26582 |
NN |
denotes |
import |
T9247 |
26583-26592 |
VBG |
denotes |
following |
T9248 |
26593-26601 |
JJ |
denotes |
anti-CD3 |
T9249 |
26601-26602 |
NN |
denotes |
/ |
T9250 |
26602-26606 |
CD |
denotes |
CD28 |
T9251 |
26607-26618 |
NN |
denotes |
stimulation |
T9252 |
26619-26622 |
IN |
denotes |
for |
T9253 |
26623-26625 |
CD |
denotes |
30 |
T9254 |
26626-26629 |
NN |
denotes |
min |
T9255 |
26630-26633 |
VBD |
denotes |
was |
T9256 |
26634-26644 |
VBN |
denotes |
attenuated |
T9257 |
26645-26647 |
IN |
denotes |
by |
T9258 |
26648-26660 |
NN |
denotes |
pretreatment |
T9259 |
26661-26665 |
IN |
denotes |
with |
T9260 |
26666-26668 |
NNP |
denotes |
FP |
T9261 |
26669-26670 |
-LRB- |
denotes |
( |
T9262 |
26670-26672 |
CD |
denotes |
10 |
T9263 |
26672-26673 |
NN |
denotes |
− |
T9264 |
26673-26674 |
CD |
denotes |
8 |
T9265 |
26675-26676 |
NNP |
denotes |
M |
T9266 |
26676-26677 |
-RRB- |
denotes |
) |
T9267 |
26678-26679 |
-LRB- |
denotes |
( |
T9268 |
26679-26685 |
NN |
denotes |
Figure |
T9269 |
26686-26688 |
CD |
denotes |
2D |
T9270 |
26688-26689 |
-RRB- |
denotes |
) |
T9271 |
26689-26690 |
. |
denotes |
. |
T17105 |
26735-26746 |
NNP |
denotes |
Fluticasone |
T17106 |
26747-26757 |
NN |
denotes |
propionate |
T17107 |
26758-26765 |
VBZ |
denotes |
reduces |
T17108 |
26766-26772 |
JJ |
denotes |
GATA-3 |
T17109 |
26773-26784 |
NN |
denotes |
association |
T17110 |
26785-26789 |
IN |
denotes |
with |
T17111 |
26790-26800 |
JJ |
denotes |
importin-α |
T17112 |
26801-26804 |
CC |
denotes |
and |
T17113 |
26805-26811 |
JJ |
denotes |
GATA-3 |
T17114 |
26812-26819 |
JJ |
denotes |
nuclear |
T17115 |
26820-26826 |
NN |
denotes |
import |
T17116 |
26826-26827 |
. |
denotes |
. |
T17117 |
26828-26829 |
-LRB- |
denotes |
( |
T17118 |
26829-26830 |
NN |
denotes |
A |
T17119 |
26830-26831 |
-RRB- |
denotes |
) |
T17120 |
26832-26839 |
JJ |
denotes |
Western |
T17121 |
26840-26844 |
NN |
denotes |
blot |
T17122 |
26845-26853 |
NN |
denotes |
analysis |
T17123 |
26854-26866 |
VBZ |
denotes |
demonstrates |
T17124 |
26867-26868 |
DT |
denotes |
a |
T17125 |
26869-26873 |
NN |
denotes |
time |
T17126 |
26873-26874 |
: |
denotes |
- |
T17127 |
26875-26876 |
-LRB- |
denotes |
( |
T17128 |
26876-26878 |
IN |
denotes |
at |
T17129 |
26879-26881 |
CD |
denotes |
10 |
T17130 |
26881-26882 |
NN |
denotes |
− |
T17131 |
26882-26883 |
CD |
denotes |
8 |
T17132 |
26884-26885 |
NNP |
denotes |
M |
T17133 |
26886-26888 |
NNP |
denotes |
FP |
T17134 |
26888-26889 |
-RRB- |
denotes |
) |
T17135 |
26890-26893 |
CC |
denotes |
and |
T17136 |
26894-26907 |
NN |
denotes |
concentration |
T17137 |
26907-26908 |
: |
denotes |
- |
T17138 |
26909-26910 |
-LRB- |
denotes |
( |
T17139 |
26910-26912 |
IN |
denotes |
at |
T17140 |
26913-26915 |
CD |
denotes |
60 |
T17141 |
26916-26919 |
NN |
denotes |
min |
T17142 |
26920-26925 |
IN |
denotes |
after |
T17143 |
26926-26937 |
NN |
denotes |
stimulation |
T17144 |
26937-26938 |
-RRB- |
denotes |
) |
T17145 |
26939-26948 |
JJ |
denotes |
dependent |
T17146 |
26949-26958 |
NN |
denotes |
induction |
T17147 |
26959-26961 |
IN |
denotes |
of |
T17148 |
26962-26974 |
JJ |
denotes |
FP-activated |
T17149 |
26975-26977 |
NNP |
denotes |
GR |
T17150 |
26978-26989 |
NN |
denotes |
interaction |
T17151 |
26990-26994 |
IN |
denotes |
with |
T17152 |
26995-27005 |
JJ |
denotes |
importin-α |
T17153 |
27006-27007 |
-LRB- |
denotes |
( |
T17154 |
27007-27012 |
JJ |
denotes |
Imp-α |
T17155 |
27012-27013 |
-RRB- |
denotes |
) |
T17156 |
27013-27014 |
. |
denotes |
. |
T17157 |
27015-27016 |
DT |
denotes |
A |
T17158 |
27017-27025 |
JJ |
denotes |
positive |
T17159 |
27026-27033 |
NN |
denotes |
control |
T17160 |
27034-27037 |
IN |
denotes |
for |
T17161 |
27038-27040 |
NNP |
denotes |
GR |
T17162 |
27041-27052 |
NN |
denotes |
association |
T17163 |
27053-27057 |
IN |
denotes |
with |
T17164 |
27058-27066 |
NN |
denotes |
importin |
T17165 |
27067-27069 |
VBZ |
denotes |
is |
T17166 |
27070-27075 |
VBN |
denotes |
shown |
T17167 |
27075-27076 |
. |
denotes |
. |
T17168 |
27077-27091 |
NN |
denotes |
Quantification |
T17169 |
27092-27094 |
IN |
denotes |
of |
T17170 |
27095-27098 |
DT |
denotes |
the |
T17171 |
27099-27111 |
NN |
denotes |
densitometry |
T17172 |
27112-27116 |
NN |
denotes |
data |
T17173 |
27117-27119 |
VBZ |
denotes |
is |
T17174 |
27120-27125 |
VBN |
denotes |
shown |
T17175 |
27126-27131 |
IN |
denotes |
below |
T17176 |
27131-27132 |
. |
denotes |
. |
T17177 |
27133-27137 |
DT |
denotes |
Each |
T17178 |
27138-27141 |
NN |
denotes |
bar |
T17179 |
27142-27152 |
VBZ |
denotes |
represents |
T17180 |
27153-27157 |
JJ |
denotes |
mean |
T17181 |
27157-27158 |
NN |
denotes |
± |
T17182 |
27158-27161 |
NNP |
denotes |
SEM |
T17183 |
27162-27164 |
IN |
denotes |
of |
T17184 |
27165-27167 |
IN |
denotes |
at |
T17185 |
27168-27173 |
JJS |
denotes |
least |
T17186 |
27174-27179 |
CD |
denotes |
three |
T17187 |
27180-27191 |
JJ |
denotes |
independent |
T17188 |
27192-27203 |
NNS |
denotes |
experiments |
T17189 |
27203-27204 |
. |
denotes |
. |
T17190 |
27205-27208 |
FW |
denotes |
*** |
T17191 |
27209-27210 |
FW |
denotes |
p |
T17192 |
27210-27211 |
FW |
denotes |
< |
T17193 |
27211-27216 |
CD |
denotes |
0.001 |
T17194 |
27217-27225 |
VBN |
denotes |
compared |
T17195 |
27226-27228 |
TO |
denotes |
to |
T17196 |
27229-27236 |
VB |
denotes |
control |
T17197 |
27236-27237 |
, |
denotes |
, |
T17198 |
27238-27241 |
FW |
denotes |
### |
T17199 |
27242-27243 |
FW |
denotes |
p |
T17200 |
27243-27244 |
FW |
denotes |
< |
T17201 |
27244-27249 |
CD |
denotes |
0.001 |
T17202 |
27249-27250 |
. |
denotes |
. |
T17203 |
27251-27252 |
-LRB- |
denotes |
( |
T17204 |
27252-27253 |
NNP |
denotes |
B |
T17205 |
27253-27254 |
-RRB- |
denotes |
) |
T17206 |
27255-27262 |
NNP |
denotes |
Western |
T17207 |
27263-27267 |
NN |
denotes |
blot |
T17208 |
27268-27276 |
NN |
denotes |
analysis |
T17209 |
27277-27289 |
VBD |
denotes |
demonstrated |
T17210 |
27290-27291 |
DT |
denotes |
a |
T17211 |
27292-27296 |
NN |
denotes |
time |
T17212 |
27296-27297 |
: |
denotes |
- |
T17213 |
27298-27299 |
-LRB- |
denotes |
( |
T17214 |
27299-27301 |
IN |
denotes |
at |
T17215 |
27302-27304 |
CD |
denotes |
10 |
T17216 |
27304-27305 |
NN |
denotes |
− |
T17217 |
27305-27306 |
CD |
denotes |
8 |
T17218 |
27307-27308 |
NNP |
denotes |
M |
T17219 |
27309-27311 |
NNP |
denotes |
FP |
T17220 |
27311-27312 |
-RRB- |
denotes |
) |
T17221 |
27313-27316 |
CC |
denotes |
and |
T17222 |
27317-27330 |
NN |
denotes |
concentration |
T17223 |
27330-27331 |
: |
denotes |
- |
T17224 |
27332-27333 |
-LRB- |
denotes |
( |
T17225 |
27333-27335 |
IN |
denotes |
at |
T17226 |
27336-27338 |
CD |
denotes |
60 |
T17227 |
27339-27342 |
NN |
denotes |
min |
T17228 |
27343-27348 |
IN |
denotes |
after |
T17229 |
27349-27360 |
NN |
denotes |
stimulation |
T17230 |
27360-27361 |
-RRB- |
denotes |
) |
T17231 |
27362-27371 |
JJ |
denotes |
dependent |
T17232 |
27372-27381 |
NN |
denotes |
induction |
T17233 |
27382-27384 |
IN |
denotes |
of |
T17234 |
27385-27397 |
JJ |
denotes |
FP-activated |
T17235 |
27398-27400 |
NNP |
denotes |
GR |
T17236 |
27401-27408 |
JJ |
denotes |
nuclear |
T17237 |
27409-27422 |
NN |
denotes |
translocation |
T17238 |
27423-27431 |
VBN |
denotes |
measured |
T17239 |
27432-27434 |
IN |
denotes |
by |
T17240 |
27435-27437 |
NNP |
denotes |
IP |
T17241 |
27437-27438 |
. |
denotes |
. |
T17242 |
27439-27453 |
NN |
denotes |
Quantification |
T17243 |
27454-27456 |
IN |
denotes |
of |
T17244 |
27457-27460 |
DT |
denotes |
the |
T17245 |
27461-27473 |
NN |
denotes |
densitometry |
T17246 |
27474-27478 |
NN |
denotes |
data |
T17247 |
27479-27481 |
VBZ |
denotes |
is |
T17248 |
27482-27487 |
VBN |
denotes |
shown |
T17249 |
27488-27493 |
IN |
denotes |
below |
T17250 |
27493-27494 |
. |
denotes |
. |
T17251 |
27495-27499 |
DT |
denotes |
Each |
T17252 |
27500-27503 |
NN |
denotes |
bar |
T17253 |
27504-27514 |
VBZ |
denotes |
represents |
T17254 |
27515-27519 |
JJ |
denotes |
mean |
T17255 |
27519-27520 |
NN |
denotes |
± |
T17256 |
27520-27523 |
NNP |
denotes |
SEM |
T17257 |
27524-27526 |
IN |
denotes |
of |
T17258 |
27527-27529 |
IN |
denotes |
at |
T17259 |
27530-27535 |
JJS |
denotes |
least |
T17260 |
27536-27541 |
CD |
denotes |
three |
T17261 |
27542-27553 |
JJ |
denotes |
independent |
T17262 |
27554-27565 |
NNS |
denotes |
experiments |
T17263 |
27565-27566 |
. |
denotes |
. |
T17264 |
27567-27570 |
FW |
denotes |
*** |
T17265 |
27570-27571 |
FW |
denotes |
p |
T17266 |
27571-27572 |
FW |
denotes |
< |
T17267 |
27572-27577 |
CD |
denotes |
0.001 |
T17268 |
27578-27586 |
VBN |
denotes |
compared |
T17269 |
27587-27589 |
TO |
denotes |
to |
T17270 |
27590-27597 |
VB |
denotes |
control |
T17271 |
27597-27598 |
. |
denotes |
. |
T17272 |
27599-27600 |
-LRB- |
denotes |
( |
T17273 |
27600-27601 |
$ |
denotes |
C |
T17274 |
27601-27602 |
-RRB- |
denotes |
) |
T17275 |
27603-27610 |
JJ |
denotes |
Western |
T17276 |
27611-27615 |
NN |
denotes |
blot |
T17277 |
27616-27624 |
NN |
denotes |
analysis |
T17278 |
27625-27627 |
IN |
denotes |
of |
T17279 |
27628-27634 |
JJ |
denotes |
HuT-78 |
T17280 |
27635-27640 |
NNS |
denotes |
cells |
T17281 |
27641-27648 |
VBN |
denotes |
treated |
T17282 |
27649-27653 |
IN |
denotes |
with |
T17283 |
27654-27656 |
NNP |
denotes |
FP |
T17284 |
27657-27660 |
CC |
denotes |
and |
T17285 |
27661-27669 |
JJ |
denotes |
anti-CD3 |
T17286 |
27669-27670 |
NN |
denotes |
/ |
T17287 |
27670-27674 |
CD |
denotes |
CD28 |
T17288 |
27675-27689 |
NN |
denotes |
co-stimulation |
T17289 |
27690-27702 |
VBD |
denotes |
demonstrated |
T17290 |
27703-27704 |
DT |
denotes |
a |
T17291 |
27705-27728 |
JJ |
denotes |
concentration-dependent |
T17292 |
27729-27737 |
NN |
denotes |
decrease |
T17293 |
27738-27740 |
IN |
denotes |
in |
T17294 |
27741-27747 |
NNP |
denotes |
GATA-3 |
T17295 |
27748-27758 |
JJ |
denotes |
importin-α |
T17296 |
27759-27770 |
NN |
denotes |
association |
T17297 |
27771-27773 |
IN |
denotes |
at |
T17298 |
27774-27776 |
CD |
denotes |
20 |
T17299 |
27777-27780 |
NN |
denotes |
min |
T17300 |
27780-27781 |
. |
denotes |
. |
T17301 |
27782-27796 |
NN |
denotes |
Quantification |
T17302 |
27797-27799 |
IN |
denotes |
of |
T17303 |
27800-27803 |
DT |
denotes |
the |
T17304 |
27804-27816 |
NN |
denotes |
densitometry |
T17305 |
27817-27821 |
NN |
denotes |
data |
T17306 |
27822-27824 |
VBZ |
denotes |
is |
T17307 |
27825-27830 |
VBN |
denotes |
shown |
T17308 |
27831-27836 |
IN |
denotes |
below |
T17309 |
27836-27837 |
. |
denotes |
. |
T17310 |
27838-27842 |
DT |
denotes |
Each |
T17311 |
27843-27846 |
NN |
denotes |
bar |
T17312 |
27847-27857 |
VBZ |
denotes |
represents |
T17313 |
27858-27862 |
JJ |
denotes |
mean |
T17314 |
27862-27863 |
NN |
denotes |
± |
T17315 |
27863-27866 |
NNP |
denotes |
SEM |
T17316 |
27867-27869 |
IN |
denotes |
of |
T17317 |
27870-27872 |
IN |
denotes |
at |
T17318 |
27873-27878 |
JJS |
denotes |
least |
T17319 |
27879-27884 |
CD |
denotes |
three |
T17320 |
27885-27896 |
JJ |
denotes |
independent |
T17321 |
27897-27908 |
NNS |
denotes |
experiments |
T17322 |
27908-27909 |
. |
denotes |
. |
T17323 |
27910-27913 |
FW |
denotes |
### |
T17337 |
27966-27970 |
JJ |
denotes |
αCD3 |
T18017 |
27966-27970 |
JJ |
denotes |
αCD3 |
T17338 |
27970-27971 |
NN |
denotes |
/ |
T18018 |
27970-27971 |
NN |
denotes |
/ |
T17339 |
27971-27986 |
JJ |
denotes |
CD28-stimulated |
T18019 |
27971-27986 |
JJ |
denotes |
CD28-stimulated |
T17340 |
27987-27992 |
NNS |
denotes |
cells |
T18020 |
27987-27992 |
NNS |
denotes |
cells |
T17341 |
27992-27993 |
. |
denotes |
. |
T18021 |
27992-27993 |
. |
denotes |
. |
T17342 |
27994-27995 |
-LRB- |
denotes |
( |
T18022 |
27994-27995 |
-LRB- |
denotes |
( |
T17343 |
27995-27996 |
NNP |
denotes |
D |
T18023 |
27995-27996 |
NNP |
denotes |
D |
T17344 |
27996-27997 |
-RRB- |
denotes |
) |
T18024 |
27996-27997 |
-RRB- |
denotes |
) |
T17345 |
27998-28008 |
JJ |
denotes |
GFP-tagged |
T17346 |
28009-28015 |
NN |
denotes |
GATA-3 |
T17347 |
28016-28019 |
VBD |
denotes |
was |
T17348 |
28020-28033 |
VBN |
denotes |
overexpressed |
T17349 |
28034-28037 |
CC |
denotes |
and |
T17350 |
28038-28043 |
NNS |
denotes |
cells |
T17351 |
28044-28054 |
VBN |
denotes |
stimulated |
T17352 |
28055-28056 |
-LRB- |
denotes |
( |
T17353 |
28056-28057 |
NN |
denotes |
b |
T17354 |
28057-28058 |
, |
denotes |
, |
T17355 |
28059-28060 |
NN |
denotes |
c |
T17356 |
28060-28061 |
-RRB- |
denotes |
) |
T17357 |
28062-28064 |
CC |
denotes |
or |
T17358 |
28065-28068 |
RB |
denotes |
not |
T17359 |
28069-28070 |
-LRB- |
denotes |
( |
T17360 |
28070-28071 |
DT |
denotes |
a |
T17361 |
28071-28072 |
-RRB- |
denotes |
) |
T17362 |
28073-28076 |
IN |
denotes |
for |
T17363 |
28077-28079 |
CD |
denotes |
30 |
T17364 |
28080-28083 |
NN |
denotes |
min |
T17365 |
28084-28088 |
IN |
denotes |
with |
T17366 |
28089-28097 |
JJ |
denotes |
anti-CD3 |
T17367 |
28097-28098 |
NN |
denotes |
/ |
T17368 |
28098-28102 |
NNP |
denotes |
CD28 |
T17369 |
28102-28103 |
. |
denotes |
. |
T17370 |
28104-28107 |
DT |
denotes |
The |
T17371 |
28108-28114 |
NN |
denotes |
effect |
T17372 |
28115-28117 |
IN |
denotes |
of |
T17373 |
28118-28120 |
CD |
denotes |
30 |
T17374 |
28121-28124 |
NN |
denotes |
min |
T17375 |
28125-28137 |
NN |
denotes |
pretreatment |
T17376 |
28138-28140 |
IN |
denotes |
of |
T17377 |
28141-28146 |
NNS |
denotes |
cells |
T17378 |
28147-28151 |
IN |
denotes |
with |
T17379 |
28152-28154 |
NNP |
denotes |
FP |
T17380 |
28155-28156 |
-LRB- |
denotes |
( |
T17381 |
28156-28158 |
CD |
denotes |
10 |
T17382 |
28158-28159 |
NN |
denotes |
− |
T17383 |
28159-28160 |
CD |
denotes |
8 |
T17384 |
28161-28162 |
NNP |
denotes |
M |
T17385 |
28162-28163 |
, |
denotes |
, |
T17386 |
28164-28165 |
NN |
denotes |
c |
T17387 |
28165-28166 |
-RRB- |
denotes |
) |
T17388 |
28167-28169 |
VBZ |
denotes |
is |
T17389 |
28170-28174 |
RB |
denotes |
also |
T17390 |
28175-28180 |
VBN |
denotes |
shown |
T17391 |
28180-28181 |
. |
denotes |
. |
T17392 |
28182-28185 |
DT |
denotes |
All |
T17393 |
28186-28190 |
NNS |
denotes |
data |
T17394 |
28191-28195 |
VBD |
denotes |
were |
T17395 |
28196-28204 |
VBN |
denotes |
analysed |
T17396 |
28205-28207 |
IN |
denotes |
by |
T17397 |
28208-28213 |
NNP |
denotes |
ANOVA |
T17398 |
28214-28222 |
VBD |
denotes |
followed |
T17399 |
28223-28225 |
IN |
denotes |
by |
T17400 |
28226-28238 |
NNP |
denotes |
Newman-Keuls |
T17401 |
28239-28248 |
JJS |
denotes |
post-test |
T17402 |
28248-28249 |
. |
denotes |
. |
T10194 |
28251-28257 |
NN |
denotes |
Effect |
T10195 |
28258-28260 |
IN |
denotes |
on |
T10196 |
28261-28266 |
NNP |
denotes |
MKP-1 |
T10197 |
28267-28280 |
NNP |
denotes |
Dexamethasone |
T10198 |
28281-28289 |
VBZ |
denotes |
inhibits |
T10199 |
28290-28293 |
CD |
denotes |
p38 |
T10200 |
28294-28298 |
NNP |
denotes |
MAPK |
T10201 |
28299-28307 |
NN |
denotes |
function |
T10202 |
28308-28310 |
IN |
denotes |
in |
T10203 |
28311-28312 |
DT |
denotes |
a |
T10204 |
28313-28317 |
NN |
denotes |
cell |
T10205 |
28318-28322 |
NN |
denotes |
type |
T10206 |
28323-28331 |
JJ |
denotes |
specific |
T10207 |
28332-28338 |
NN |
denotes |
manner |
T10208 |
28339-28346 |
IN |
denotes |
through |
T10209 |
28347-28350 |
DT |
denotes |
the |
T10210 |
28351-28356 |
JJ |
denotes |
rapid |
T10211 |
28357-28366 |
NN |
denotes |
induction |
T10212 |
28367-28369 |
IN |
denotes |
of |
T10213 |
28370-28373 |
DT |
denotes |
the |
T10214 |
28374-28378 |
JJ |
denotes |
dual |
T10215 |
28379-28385 |
NN |
denotes |
kinase |
T10216 |
28386-28397 |
NN |
denotes |
phosphatase |
T10217 |
28398-28403 |
NNP |
denotes |
MKP-1 |
T10218 |
28404-28405 |
-LRB- |
denotes |
( |
T10219 |
28405-28409 |
NNP |
denotes |
MAPK |
T10220 |
28410-28423 |
JJ |
denotes |
phosphatase-1 |
T10221 |
28423-28424 |
-RRB- |
denotes |
) |
T10222 |
28424-28425 |
, |
denotes |
, |
T10223 |
28426-28429 |
CC |
denotes |
and |
T10224 |
28430-28434 |
DT |
denotes |
this |
T10225 |
28435-28441 |
NN |
denotes |
effect |
T10226 |
28442-28447 |
VBZ |
denotes |
lasts |
T10227 |
28448-28451 |
IN |
denotes |
for |
T10228 |
28452-28454 |
RB |
denotes |
up |
T10229 |
28455-28457 |
TO |
denotes |
to |
T10230 |
28458-28460 |
CD |
denotes |
24 |
T10231 |
28461-28462 |
NN |
denotes |
h |
T10232 |
28463-28464 |
NNP |
denotes |
[ |
T10233 |
28464-28466 |
CD |
denotes |
28 |
T10234 |
28466-28467 |
NNP |
denotes |
] |
T10235 |
28467-28468 |
. |
denotes |
. |
T10236 |
28469-28471 |
NNP |
denotes |
FP |
T10237 |
28472-28473 |
-LRB- |
denotes |
( |
T10238 |
28473-28475 |
CD |
denotes |
10 |
T10239 |
28475-28476 |
NN |
denotes |
− |
T10240 |
28476-28477 |
CD |
denotes |
8 |
T10241 |
28478-28479 |
NNP |
denotes |
M |
T10242 |
28479-28480 |
-RRB- |
denotes |
) |
T10243 |
28481-28490 |
NN |
denotes |
treatment |
T10244 |
28491-28493 |
IN |
denotes |
of |
T10245 |
28494-28500 |
JJ |
denotes |
HuT-78 |
T10246 |
28501-28506 |
NNS |
denotes |
cells |
T10247 |
28507-28516 |
VBN |
denotes |
activated |
T10248 |
28517-28519 |
IN |
denotes |
by |
T10249 |
28520-28528 |
JJ |
denotes |
anti-CD3 |
T10250 |
28528-28529 |
NN |
denotes |
/ |
T10251 |
28529-28533 |
CD |
denotes |
CD28 |
T10252 |
28534-28536 |
IN |
denotes |
in |
T10253 |
28537-28542 |
NN |
denotes |
vitro |
T10254 |
28543-28556 |
RB |
denotes |
significantly |
T10255 |
28557-28566 |
VBD |
denotes |
decreased |
T10256 |
28567-28570 |
CD |
denotes |
p38 |
T10257 |
28571-28575 |
NNP |
denotes |
MAPK |
T10258 |
28576-28591 |
NN |
denotes |
phosphorylation |
T10259 |
28592-28593 |
-LRB- |
denotes |
( |
T10260 |
28593-28599 |
NN |
denotes |
Figure |
T10261 |
28600-28602 |
NN |
denotes |
3A |
T10262 |
28602-28603 |
-RRB- |
denotes |
) |
T10263 |
28604-28607 |
CC |
denotes |
and |
T10264 |
28608-28616 |
NN |
denotes |
activity |
T10265 |
28617-28625 |
VBN |
denotes |
measured |
T10266 |
28626-28628 |
IN |
denotes |
by |
T10267 |
28629-28644 |
NN |
denotes |
phosphorylation |
T10268 |
28645-28647 |
IN |
denotes |
of |
T10269 |
28648-28651 |
DT |
denotes |
the |
T10270 |
28652-28662 |
JJ |
denotes |
downstream |
T10271 |
28663-28669 |
NN |
denotes |
target |
T10272 |
28670-28675 |
NNP |
denotes |
ATF-2 |
T10273 |
28676-28677 |
-LRB- |
denotes |
( |
T10274 |
28677-28683 |
NNP |
denotes |
Figure |
T10275 |
28684-28686 |
NNP |
denotes |
3B |
T10276 |
28686-28687 |
-RRB- |
denotes |
) |
T10277 |
28687-28688 |
. |
denotes |
. |
T10278 |
28689-28693 |
DT |
denotes |
This |
T10279 |
28694-28700 |
NN |
denotes |
effect |
T10280 |
28701-28704 |
VBD |
denotes |
was |
T10281 |
28705-28713 |
VBN |
denotes |
detected |
T10282 |
28714-28716 |
IN |
denotes |
at |
T10283 |
28717-28719 |
CD |
denotes |
30 |
T10284 |
28720-28723 |
NN |
denotes |
min |
T10285 |
28724-28727 |
CC |
denotes |
and |
T10286 |
28728-28734 |
VBD |
denotes |
lasted |
T10287 |
28735-28738 |
IN |
denotes |
for |
T10288 |
28739-28741 |
IN |
denotes |
at |
T10289 |
28742-28747 |
JJS |
denotes |
least |
T10290 |
28748-28750 |
CD |
denotes |
14 |
T10291 |
28751-28752 |
NN |
denotes |
h |
T10292 |
28753-28754 |
-LRB- |
denotes |
( |
T10293 |
28754-28760 |
NN |
denotes |
Figure |
T10294 |
28761-28763 |
NN |
denotes |
3B |
T10295 |
28763-28764 |
-RRB- |
denotes |
) |
T10296 |
28764-28765 |
. |
denotes |
. |
T10297 |
28766-28768 |
NNP |
denotes |
FP |
T10298 |
28769-28770 |
-LRB- |
denotes |
( |
T10299 |
28770-28772 |
CD |
denotes |
10 |
T10300 |
28772-28773 |
NN |
denotes |
− |
T10301 |
28773-28774 |
CD |
denotes |
8 |
T10302 |
28775-28776 |
NNP |
denotes |
M |
T10303 |
28776-28777 |
-RRB- |
denotes |
) |
T10304 |
28778-28782 |
RB |
denotes |
also |
T10305 |
28783-28796 |
RB |
denotes |
significantly |
T10306 |
28797-28804 |
VBN |
denotes |
reduced |
T10307 |
28805-28811 |
JJ |
denotes |
GATA-3 |
T10308 |
28812-28818 |
NN |
denotes |
serine |
T10309 |
28819-28834 |
NN |
denotes |
phosphorylation |
T10310 |
28835-28842 |
VBN |
denotes |
induced |
T10311 |
28843-28845 |
IN |
denotes |
by |
T10312 |
28846-28854 |
JJ |
denotes |
anti-CD3 |
T10313 |
28854-28855 |
NN |
denotes |
/ |
T10314 |
28855-28859 |
CD |
denotes |
CD28 |
T10315 |
28860-28871 |
NN |
denotes |
stimulation |
T10316 |
28872-28874 |
IN |
denotes |
in |
T10317 |
28875-28879 |
DT |
denotes |
both |
T10318 |
28880-28881 |
DT |
denotes |
a |
T10319 |
28882-28886 |
NN |
denotes |
time |
T10320 |
28886-28887 |
: |
denotes |
- |
T10321 |
28888-28891 |
CC |
denotes |
and |
T10322 |
28892-28915 |
JJ |
denotes |
concentration-dependent |
T10323 |
28916-28922 |
NN |
denotes |
manner |
T10324 |
28923-28924 |
-LRB- |
denotes |
( |
T10325 |
28924-28930 |
NN |
denotes |
Figure |
T10326 |
28931-28933 |
NN |
denotes |
3C |
T10327 |
28933-28934 |
-RRB- |
denotes |
) |
T10328 |
28934-28935 |
. |
denotes |
. |
T10329 |
28936-28940 |
DT |
denotes |
This |
T10330 |
28941-28950 |
NN |
denotes |
reduction |
T10331 |
28951-28953 |
IN |
denotes |
in |
T10332 |
28954-28960 |
JJ |
denotes |
GATA-3 |
T10333 |
28961-28976 |
NN |
denotes |
phosphorylation |
T10334 |
28977-28980 |
VBD |
denotes |
was |
T10335 |
28981-28985 |
RB |
denotes |
also |
T10336 |
28986-28990 |
VBN |
denotes |
seen |
T10337 |
28991-28995 |
IN |
denotes |
with |
T10338 |
28996-29001 |
JJR |
denotes |
lower |
T10339 |
29002-29016 |
NNS |
denotes |
concentrations |
T10340 |
29017-29019 |
IN |
denotes |
of |
T10341 |
29020-29022 |
NNP |
denotes |
FP |
T10342 |
29022-29023 |
. |
denotes |
. |
T10343 |
29024-29026 |
PRP |
denotes |
We |
T10344 |
29027-29032 |
VBD |
denotes |
found |
T10345 |
29033-29037 |
IN |
denotes |
that |
T10346 |
29038-29040 |
NNP |
denotes |
FP |
T10347 |
29041-29054 |
RB |
denotes |
significantly |
T10348 |
29055-29062 |
VBD |
denotes |
induced |
T10349 |
29063-29068 |
NNP |
denotes |
MKP-1 |
T10350 |
29069-29073 |
NNP |
denotes |
mRNA |
T10351 |
29074-29076 |
IN |
denotes |
in |
T10352 |
29077-29081 |
DT |
denotes |
both |
T10353 |
29082-29083 |
DT |
denotes |
a |
T10354 |
29084-29088 |
NN |
denotes |
time |
T10355 |
29088-29089 |
: |
denotes |
- |
T10356 |
29090-29093 |
CC |
denotes |
and |
T10357 |
29094-29117 |
JJ |
denotes |
concentration-dependent |
T10358 |
29118-29124 |
NN |
denotes |
manner |
T10359 |
29124-29125 |
, |
denotes |
, |
T10360 |
29126-29134 |
VBG |
denotes |
reaching |
T10361 |
29135-29136 |
DT |
denotes |
a |
T10362 |
29137-29144 |
NN |
denotes |
plateau |
T10363 |
29145-29147 |
IN |
denotes |
at |
T10364 |
29148-29150 |
CD |
denotes |
10 |
T10365 |
29150-29151 |
NN |
denotes |
− |
T10366 |
29151-29152 |
CD |
denotes |
8 |
T10367 |
29153-29154 |
NNP |
denotes |
M |
T10368 |
29155-29160 |
IN |
denotes |
after |
T10369 |
29161-29163 |
CD |
denotes |
10 |
T10370 |
29164-29167 |
NN |
denotes |
min |
T10371 |
29168-29169 |
-LRB- |
denotes |
( |
T10372 |
29169-29175 |
NN |
denotes |
Figure |
T10373 |
29176-29178 |
CD |
denotes |
3D |
T10374 |
29179-29182 |
CC |
denotes |
and |
T10375 |
29183-29185 |
CD |
denotes |
3E |
T10376 |
29185-29186 |
-RRB- |
denotes |
) |
T10377 |
29186-29187 |
. |
denotes |
. |
T10378 |
29188-29195 |
RB |
denotes |
However |
T10379 |
29195-29196 |
, |
denotes |
, |
T10380 |
29197-29200 |
DT |
denotes |
the |
T10381 |
29201-29208 |
NNS |
denotes |
effects |
T10382 |
29209-29211 |
IN |
denotes |
of |
T10383 |
29212-29214 |
NNP |
denotes |
FP |
T10384 |
29215-29217 |
IN |
denotes |
on |
T10385 |
29218-29224 |
NNP |
denotes |
GATA-3 |
T10386 |
29225-29232 |
JJ |
denotes |
nuclear |
T10387 |
29233-29239 |
NN |
denotes |
import |
T10388 |
29239-29240 |
, |
denotes |
, |
T10389 |
29241-29251 |
JJ |
denotes |
importin-α |
T10390 |
29252-29263 |
NN |
denotes |
association |
T10391 |
29264-29267 |
CC |
denotes |
and |
T10392 |
29268-29272 |
NN |
denotes |
IL-4 |
T10393 |
29273-29277 |
NNP |
denotes |
mRNA |
T10394 |
29278-29288 |
NN |
denotes |
expression |
T10395 |
29289-29292 |
VBP |
denotes |
are |
T10396 |
29293-29297 |
VBN |
denotes |
seen |
T10397 |
29298-29300 |
IN |
denotes |
at |
T10398 |
29301-29312 |
CD |
denotes |
10,000-fold |
T10399 |
29313-29318 |
JJR |
denotes |
lower |
T10400 |
29319-29333 |
NNS |
denotes |
concentrations |
T10401 |
29334-29335 |
-LRB- |
denotes |
( |
T10402 |
29335-29337 |
CD |
denotes |
10 |
T10403 |
29337-29338 |
NN |
denotes |
− |
T10404 |
29338-29340 |
CD |
denotes |
12 |
T10405 |
29341-29342 |
NNP |
denotes |
M |
T10406 |
29342-29343 |
, |
denotes |
, |
T10407 |
29344-29347 |
VBP |
denotes |
see |
T10408 |
29348-29354 |
NN |
denotes |
Figure |
T10409 |
29355-29356 |
CD |
denotes |
2 |
T10410 |
29356-29357 |
-RRB- |
denotes |
) |
T10411 |
29357-29358 |
. |
denotes |
. |
T17853 |
29403-29414 |
NNP |
denotes |
Fluticasone |
T17854 |
29415-29425 |
NN |
denotes |
propionate |
T17855 |
29426-29434 |
VBN |
denotes |
mediated |
T17856 |
29435-29445 |
NN |
denotes |
inhibition |
T17857 |
29446-29448 |
IN |
denotes |
of |
T17858 |
29449-29452 |
CD |
denotes |
p38 |
T17859 |
29453-29456 |
NNP |
denotes |
MAP |
T17860 |
29457-29463 |
NN |
denotes |
kinase |
T17861 |
29464-29479 |
NN |
denotes |
phosphorylation |
T17862 |
29480-29483 |
CC |
denotes |
and |
T17863 |
29484-29494 |
NN |
denotes |
activation |
T17864 |
29495-29497 |
VBZ |
denotes |
is |
T17865 |
29498-29508 |
VBN |
denotes |
associated |
T17866 |
29509-29513 |
IN |
denotes |
with |
T17867 |
29514-29515 |
DT |
denotes |
a |
T17868 |
29516-29522 |
JJ |
denotes |
marked |
T17869 |
29523-29538 |
NN |
denotes |
down-regulation |
T17870 |
29539-29541 |
IN |
denotes |
of |
T17871 |
29542-29548 |
JJ |
denotes |
GATA-3 |
T17872 |
29549-29555 |
NN |
denotes |
serine |
T17873 |
29556-29571 |
NN |
denotes |
phosphorylation |
T17874 |
29571-29572 |
. |
denotes |
. |
T17875 |
29573-29574 |
-LRB- |
denotes |
( |
T17876 |
29574-29575 |
NN |
denotes |
A |
T17877 |
29575-29576 |
-RRB- |
denotes |
) |
T17878 |
29577-29584 |
JJ |
denotes |
Western |
T17879 |
29585-29589 |
NN |
denotes |
blot |
T17880 |
29590-29598 |
NN |
denotes |
analysis |
T17881 |
29599-29604 |
VBZ |
denotes |
shows |
T17882 |
29605-29609 |
IN |
denotes |
that |
T17883 |
29610-29612 |
NNP |
denotes |
FP |
T17884 |
29613-29614 |
-LRB- |
denotes |
( |
T17885 |
29614-29616 |
CD |
denotes |
10 |
T17886 |
29616-29617 |
NN |
denotes |
− |
T17887 |
29617-29618 |
CD |
denotes |
8 |
T17888 |
29619-29620 |
NNP |
denotes |
M |
T17889 |
29620-29621 |
, |
denotes |
, |
T17890 |
29622-29624 |
CD |
denotes |
30 |
T17891 |
29625-29628 |
NN |
denotes |
min |
T17892 |
29628-29629 |
-RRB- |
denotes |
) |
T17893 |
29630-29639 |
NN |
denotes |
treatment |
T17894 |
29640-29647 |
VBD |
denotes |
reduced |
T17895 |
29648-29652 |
JJ |
denotes |
dual |
T17896 |
29653-29668 |
NN |
denotes |
phosphorylation |
T17897 |
29669-29670 |
-LRB- |
denotes |
( |
T17898 |
29670-29683 |
NN |
denotes |
threonine-180 |
T17899 |
29684-29687 |
CC |
denotes |
and |
T17900 |
29688-29700 |
NN |
denotes |
tyrosine-182 |
T17901 |
29700-29701 |
-RRB- |
denotes |
) |
T17902 |
29702-29704 |
IN |
denotes |
of |
T17903 |
29705-29708 |
CD |
denotes |
p38 |
T17904 |
29709-29713 |
NNP |
denotes |
MAPK |
T17905 |
29714-29716 |
IN |
denotes |
in |
T17906 |
29717-29725 |
JJ |
denotes |
anti-CD3 |
T17907 |
29725-29726 |
NN |
denotes |
/ |
T17908 |
29726-29730 |
CD |
denotes |
CD28 |
T17909 |
29731-29744 |
JJ |
denotes |
co-stimulated |
T17910 |
29745-29751 |
JJ |
denotes |
HuT-78 |
T17911 |
29752-29757 |
NNS |
denotes |
cells |
T17912 |
29757-29758 |
. |
denotes |
. |
T17913 |
29759-29760 |
-LRB- |
denotes |
( |
T17914 |
29760-29761 |
NNP |
denotes |
B |
T17915 |
29761-29762 |
-RRB- |
denotes |
) |
T17916 |
29763-29767 |
NNP |
denotes |
Time |
T17917 |
29768-29774 |
NN |
denotes |
course |
T17918 |
29775-29777 |
IN |
denotes |
of |
T17919 |
29778-29781 |
DT |
denotes |
the |
T17920 |
29782-29788 |
NN |
denotes |
effect |
T17921 |
29789-29791 |
IN |
denotes |
of |
T17922 |
29792-29794 |
NNP |
denotes |
FP |
T17923 |
29795-29796 |
-LRB- |
denotes |
( |
T17924 |
29796-29798 |
CD |
denotes |
10 |
T17925 |
29798-29799 |
NN |
denotes |
− |
T17926 |
29799-29800 |
CD |
denotes |
8 |
T17927 |
29801-29802 |
NNP |
denotes |
M |
T17928 |
29802-29803 |
-RRB- |
denotes |
) |
T17929 |
29804-29806 |
IN |
denotes |
on |
T17930 |
29807-29822 |
NN |
denotes |
phosphorylation |
T17931 |
29823-29825 |
IN |
denotes |
of |
T17932 |
29826-29835 |
VBN |
denotes |
activated |
T17933 |
29836-29849 |
NN |
denotes |
transcription |
T17934 |
29850-29856 |
NN |
denotes |
factor |
T17935 |
29857-29858 |
CD |
denotes |
2 |
T17936 |
29859-29860 |
-LRB- |
denotes |
( |
T17937 |
29860-29865 |
NN |
denotes |
ATF-2 |
T17938 |
29865-29866 |
-RRB- |
denotes |
) |
T17939 |
29866-29867 |
, |
denotes |
, |
T17940 |
29868-29869 |
DT |
denotes |
a |
T17941 |
29870-29877 |
NN |
denotes |
measure |
T17942 |
29878-29880 |
IN |
denotes |
of |
T17943 |
29881-29884 |
CD |
denotes |
p38 |
T17944 |
29885-29889 |
NNP |
denotes |
MAPK |
T17945 |
29890-29898 |
NN |
denotes |
activity |
T17946 |
29898-29899 |
. |
denotes |
. |
T17947 |
29900-29901 |
-LRB- |
denotes |
( |
T17948 |
29901-29902 |
$ |
denotes |
C |
T17949 |
29902-29903 |
-RRB- |
denotes |
) |
T17950 |
29904-29914 |
JJ |
denotes |
FP-induced |
T17951 |
29915-29925 |
NN |
denotes |
inhibition |
T17952 |
29926-29928 |
IN |
denotes |
of |
T17953 |
29929-29932 |
CD |
denotes |
p38 |
T17954 |
29933-29937 |
NNP |
denotes |
MAPK |
T17955 |
29938-29946 |
NN |
denotes |
activity |
T17956 |
29947-29949 |
VBZ |
denotes |
is |
T17957 |
29950-29960 |
VBN |
denotes |
associated |
T17958 |
29961-29965 |
IN |
denotes |
with |
T17959 |
29966-29969 |
DT |
denotes |
the |
T17960 |
29970-29978 |
NN |
denotes |
decrease |
T17961 |
29979-29981 |
IN |
denotes |
of |
T17962 |
29982-29990 |
JJ |
denotes |
anti-CD3 |
T17963 |
29990-29991 |
NN |
denotes |
/ |
T17964 |
29991-29995 |
CD |
denotes |
CD28 |
T17965 |
29996-30010 |
NN |
denotes |
co-stimulation |
T17966 |
30011-30018 |
VBD |
denotes |
induced |
T17967 |
30019-30025 |
JJ |
denotes |
serine |
T17968 |
30026-30041 |
NN |
denotes |
phosphorylation |
T17969 |
30042-30043 |
-LRB- |
denotes |
( |
T17970 |
30043-30048 |
NN |
denotes |
P-Ser |
T17971 |
30048-30049 |
-RRB- |
denotes |
) |
T17972 |
30050-30052 |
IN |
denotes |
of |
T17973 |
30053-30059 |
NN |
denotes |
GATA-3 |
T17974 |
30059-30060 |
. |
denotes |
. |
T17975 |
30061-30064 |
IN |
denotes |
For |
T17976 |
30065-30066 |
-LRB- |
denotes |
( |
T17977 |
30066-30067 |
DT |
denotes |
A |
T17978 |
30068-30069 |
NNP |
denotes |
C |
T17979 |
30069-30070 |
-RRB- |
denotes |
) |
T17980 |
30070-30071 |
, |
denotes |
, |
T17981 |
30072-30086 |
NN |
denotes |
quantification |
T17982 |
30087-30089 |
IN |
denotes |
of |
T17983 |
30090-30093 |
DT |
denotes |
the |
T17984 |
30094-30106 |
NN |
denotes |
densitometry |
T17985 |
30107-30111 |
NN |
denotes |
data |
T17986 |
30112-30114 |
VBZ |
denotes |
is |
T17987 |
30115-30119 |
RB |
denotes |
also |
T17988 |
30120-30125 |
VBN |
denotes |
shown |
T17989 |
30125-30126 |
. |
denotes |
. |
T17990 |
30127-30131 |
DT |
denotes |
Each |
T17991 |
30132-30135 |
NN |
denotes |
bar |
T17992 |
30136-30146 |
VBZ |
denotes |
represents |
T17993 |
30147-30151 |
JJ |
denotes |
mean |
T17994 |
30151-30152 |
NN |
denotes |
± |
T17995 |
30152-30155 |
NNP |
denotes |
SEM |
T17996 |
30156-30158 |
IN |
denotes |
of |
T17997 |
30159-30161 |
IN |
denotes |
at |
T17998 |
30162-30167 |
JJS |
denotes |
least |
T17999 |
30168-30173 |
CD |
denotes |
three |
T18000 |
30174-30185 |
JJ |
denotes |
independent |
T18001 |
30186-30197 |
NNS |
denotes |
experiments |
T18002 |
30197-30198 |
. |
denotes |
. |
T18003 |
30199-30202 |
FW |
denotes |
### |
T18025 |
30287-30289 |
NNP |
denotes |
FP |
T18026 |
30290-30297 |
VBD |
denotes |
induced |
T18027 |
30298-30303 |
NNP |
denotes |
MKP-1 |
T18028 |
30304-30308 |
NNP |
denotes |
mRNA |
T18029 |
30309-30311 |
IN |
denotes |
in |
T18030 |
30312-30313 |
DT |
denotes |
a |
T18031 |
30314-30337 |
JJ |
denotes |
concentration-dependent |
T18032 |
30338-30344 |
NN |
denotes |
manner |
T18033 |
30344-30345 |
. |
denotes |
. |
T18034 |
30346-30349 |
DT |
denotes |
All |
T18035 |
30350-30357 |
NNS |
denotes |
results |
T18036 |
30358-30361 |
VBP |
denotes |
are |
T18037 |
30362-30376 |
NN |
denotes |
representative |
T18038 |
30377-30379 |
IN |
denotes |
of |
T18039 |
30380-30382 |
IN |
denotes |
at |
T18040 |
30383-30388 |
JJS |
denotes |
least |
T18041 |
30389-30394 |
CD |
denotes |
three |
T18042 |
30395-30406 |
JJ |
denotes |
independent |
T18043 |
30407-30418 |
NNS |
denotes |
experiments |
T18044 |
30419-30422 |
CC |
denotes |
and |
T18045 |
30423-30428 |
WRB |
denotes |
where |
T18046 |
30429-30440 |
JJ |
denotes |
appropriate |
T18047 |
30441-30450 |
VBN |
denotes |
expressed |
T18048 |
30451-30453 |
IN |
denotes |
as |
T18049 |
30454-30459 |
NNS |
denotes |
means |
T18050 |
30459-30460 |
VBP |
denotes |
± |
T18051 |
30460-30463 |
NNP |
denotes |
SEM |
T18052 |
30463-30464 |
, |
denotes |
, |
T18053 |
30465-30466 |
SYM |
denotes |
* |
T18054 |
30466-30467 |
FW |
denotes |
p |
T18055 |
30467-30468 |
FW |
denotes |
< |
T18056 |
30468-30472 |
CD |
denotes |
0.05 |
T18057 |
30472-30473 |
. |
denotes |
. |
T18058 |
30474-30475 |
-LRB- |
denotes |
( |
T18059 |
30475-30476 |
NNP |
denotes |
E |
T18060 |
30476-30477 |
-RRB- |
denotes |
) |
T18061 |
30478-30480 |
NNP |
denotes |
FP |
T18062 |
30481-30488 |
VBZ |
denotes |
induces |
T18063 |
30489-30494 |
NNP |
denotes |
MKP-1 |
T18064 |
30495-30499 |
NNP |
denotes |
mRNA |
T18065 |
30500-30502 |
IN |
denotes |
in |
T18066 |
30503-30504 |
DT |
denotes |
a |
T18067 |
30505-30519 |
JJ |
denotes |
time-dependent |
T18068 |
30520-30526 |
NN |
denotes |
manner |
T18069 |
30526-30527 |
. |
denotes |
. |
T18070 |
30528-30535 |
NNS |
denotes |
Results |
T18071 |
30536-30539 |
VBP |
denotes |
are |
T18072 |
30540-30554 |
NN |
denotes |
representative |
T18073 |
30555-30557 |
IN |
denotes |
of |
T18074 |
30558-30561 |
CD |
denotes |
two |
T18075 |
30562-30573 |
JJ |
denotes |
independent |
T18076 |
30574-30585 |
NNS |
denotes |
experiments |
T18077 |
30585-30586 |
. |
denotes |
. |
T18078 |
30587-30590 |
DT |
denotes |
All |
T18079 |
30591-30595 |
NNS |
denotes |
data |
T18080 |
30596-30602 |
IN |
denotes |
except |
T18081 |
30603-30604 |
-LRB- |
denotes |
( |
T18082 |
30604-30605 |
NNP |
denotes |
E |
T18083 |
30605-30606 |
-RRB- |
denotes |
) |
T18084 |
30607-30611 |
VBD |
denotes |
were |
T18085 |
30612-30620 |
VBN |
denotes |
analysed |
T18086 |
30621-30623 |
IN |
denotes |
by |
T18087 |
30624-30629 |
NNP |
denotes |
ANOVA |
T18088 |
30630-30638 |
VBD |
denotes |
followed |
T18089 |
30639-30641 |
IN |
denotes |
by |
T18090 |
30642-30654 |
NNP |
denotes |
Newman-Keuls |
T18091 |
30655-30664 |
JJS |
denotes |
post-test |
T18092 |
30664-30665 |
. |
denotes |
. |
T10412 |
30668-30673 |
VBG |
denotes |
Using |
T10413 |
30674-30676 |
DT |
denotes |
an |
T10414 |
30677-30679 |
IN |
denotes |
in |
T10415 |
30680-30685 |
NN |
denotes |
vitro |
T10416 |
30686-30697 |
NN |
denotes |
competition |
T10417 |
30698-30703 |
NN |
denotes |
assay |
T10418 |
30704-30705 |
-LRB- |
denotes |
( |
T10419 |
30705-30711 |
NN |
denotes |
Figure |
T10420 |
30712-30714 |
NN |
denotes |
4A |
T10421 |
30714-30715 |
-RRB- |
denotes |
) |
T10422 |
30716-30725 |
VBG |
denotes |
utilizing |
T10423 |
30726-30734 |
JJ |
denotes |
purified |
T10424 |
30735-30744 |
VBN |
denotes |
activated |
T10425 |
30745-30751 |
NN |
denotes |
GATA-3 |
T10426 |
30751-30752 |
, |
denotes |
, |
T10427 |
30753-30763 |
NN |
denotes |
importin-α |
T10428 |
30763-30764 |
, |
denotes |
, |
T10429 |
30765-30768 |
CC |
denotes |
and |
T10430 |
30769-30778 |
VBD |
denotes |
activated |
T10431 |
30779-30781 |
NNP |
denotes |
GR |
T10432 |
30781-30782 |
, |
denotes |
, |
T10433 |
30783-30785 |
PRP |
denotes |
we |
T10434 |
30786-30798 |
VBD |
denotes |
demonstrated |
T10435 |
30799-30803 |
IN |
denotes |
that |
T10436 |
30804-30813 |
VBN |
denotes |
activated |
T10437 |
30814-30816 |
NNP |
denotes |
GR |
T10438 |
30817-30830 |
RB |
denotes |
significantly |
T10439 |
30831-30840 |
VBD |
denotes |
increased |
T10440 |
30841-30854 |
JJ |
denotes |
GR-importin-α |
T10441 |
30855-30866 |
NN |
denotes |
association |
T10442 |
30867-30869 |
IN |
denotes |
in |
T10443 |
30870-30873 |
DT |
denotes |
the |
T10444 |
30874-30882 |
NN |
denotes |
presence |
T10445 |
30883-30886 |
CC |
denotes |
and |
T10446 |
30887-30894 |
NN |
denotes |
absence |
T10447 |
30895-30897 |
IN |
denotes |
of |
T10448 |
30898-30907 |
VBN |
denotes |
activated |
T10449 |
30908-30914 |
NNP |
denotes |
GATA-3 |
T10450 |
30915-30916 |
-LRB- |
denotes |
( |
T10451 |
30916-30922 |
NNP |
denotes |
Figure |
T10452 |
30923-30925 |
NNP |
denotes |
4B |
T10453 |
30925-30926 |
-RRB- |
denotes |
) |
T10454 |
30926-30927 |
. |
denotes |
. |
T10455 |
30928-30932 |
DT |
denotes |
This |
T10456 |
30933-30939 |
NN |
denotes |
effect |
T10457 |
30940-30942 |
VBZ |
denotes |
is |
T10458 |
30943-30946 |
RB |
denotes |
not |
T10459 |
30947-30953 |
JJ |
denotes |
mutual |
T10460 |
30953-30954 |
, |
denotes |
, |
T10461 |
30955-30960 |
IN |
denotes |
since |
T10462 |
30961-30970 |
VBN |
denotes |
activated |
T10463 |
30971-30977 |
NNP |
denotes |
GATA-3 |
T10464 |
30978-30981 |
VBD |
denotes |
did |
T10465 |
30982-30985 |
RB |
denotes |
not |
T10466 |
30986-30991 |
VB |
denotes |
block |
T10467 |
30992-30994 |
NNP |
denotes |
GR |
T10468 |
30995-31005 |
JJ |
denotes |
importin-α |
T10469 |
31006-31017 |
NN |
denotes |
association |
T10470 |
31018-31019 |
-LRB- |
denotes |
( |
T10471 |
31019-31025 |
NN |
denotes |
Figure |
T10472 |
31026-31028 |
NN |
denotes |
4C |
T10473 |
31028-31029 |
-RRB- |
denotes |
) |
T10474 |
31029-31030 |
. |
denotes |
. |
T10475 |
31031-31036 |
DT |
denotes |
These |
T10476 |
31037-31041 |
NNS |
denotes |
data |
T10477 |
31042-31046 |
RB |
denotes |
also |
T10478 |
31047-31054 |
VBP |
denotes |
suggest |
T10479 |
31055-31059 |
IN |
denotes |
that |
T10480 |
31060-31064 |
DT |
denotes |
both |
T10481 |
31065-31074 |
VBN |
denotes |
activated |
T10482 |
31075-31077 |
NNP |
denotes |
GR |
T10483 |
31078-31081 |
CC |
denotes |
and |
T10484 |
31082-31096 |
NNP |
denotes |
phospho-GATA-3 |
T10485 |
31097-31100 |
MD |
denotes |
can |
T10486 |
31101-31109 |
RB |
denotes |
directly |
T10487 |
31110-31119 |
VB |
denotes |
associate |
T10488 |
31120-31124 |
IN |
denotes |
with |
T10489 |
31125-31135 |
JJ |
denotes |
importin-α |
T10490 |
31136-31137 |
-LRB- |
denotes |
( |
T10491 |
31137-31143 |
NNP |
denotes |
Figure |
T10492 |
31144-31146 |
NNP |
denotes |
4D |
T10493 |
31146-31147 |
-RRB- |
denotes |
) |
T10494 |
31148-31151 |
CC |
denotes |
and |
T10495 |
31152-31156 |
IN |
denotes |
that |
T10496 |
31157-31166 |
VBN |
denotes |
activated |
T10497 |
31167-31169 |
NNP |
denotes |
GR |
T10498 |
31170-31180 |
VBZ |
denotes |
attenuates |
T10499 |
31181-31184 |
DT |
denotes |
the |
T10500 |
31185-31199 |
JJ |
denotes |
phospho-GATA-3 |
T10501 |
31199-31200 |
NN |
denotes |
/ |
T10502 |
31200-31210 |
JJ |
denotes |
importin-α |
T10503 |
31211-31222 |
NN |
denotes |
interaction |
T10504 |
31223-31225 |
IN |
denotes |
in |
T10505 |
31226-31227 |
DT |
denotes |
a |
T10506 |
31228-31251 |
JJ |
denotes |
concentration-dependent |
T10507 |
31252-31258 |
NN |
denotes |
manner |
T10508 |
31259-31260 |
-LRB- |
denotes |
( |
T10509 |
31260-31266 |
NN |
denotes |
Figure |
T10510 |
31267-31269 |
CD |
denotes |
4E |
T10511 |
31269-31270 |
-RRB- |
denotes |
) |
T10512 |
31270-31271 |
. |
denotes |
. |
T10513 |
31272-31280 |
RB |
denotes |
Together |
T10514 |
31280-31281 |
, |
denotes |
, |
T10515 |
31282-31286 |
DT |
denotes |
this |
T10516 |
31287-31295 |
VBZ |
denotes |
suggests |
T10517 |
31296-31300 |
IN |
denotes |
that |
T10518 |
31301-31317 |
JJ |
denotes |
ligand-activated |
T10519 |
31318-31320 |
NNP |
denotes |
GR |
T10520 |
31321-31324 |
MD |
denotes |
may |
T10521 |
31325-31332 |
VB |
denotes |
compete |
T10522 |
31333-31337 |
IN |
denotes |
with |
T10523 |
31338-31352 |
JJ |
denotes |
phospho-GATA-3 |
T10524 |
31353-31356 |
IN |
denotes |
for |
T10525 |
31357-31367 |
JJ |
denotes |
importin-α |
T10526 |
31368-31371 |
CC |
denotes |
and |
T10527 |
31372-31379 |
RB |
denotes |
thereby |
T10528 |
31380-31385 |
NN |
denotes |
limit |
T10529 |
31386-31392 |
JJ |
denotes |
GATA-3 |
T10530 |
31393-31400 |
JJ |
denotes |
nuclear |
T10531 |
31401-31407 |
NN |
denotes |
import |
T10532 |
31407-31408 |
. |
denotes |
. |
T18334 |
31453-31464 |
NNP |
denotes |
Fluticasone |
T18335 |
31465-31475 |
NN |
denotes |
propionate |
T18336 |
31476-31484 |
VBZ |
denotes |
competes |
T18337 |
31485-31489 |
IN |
denotes |
with |
T18338 |
31490-31504 |
NN |
denotes |
phospho-GATA-3 |
T18339 |
31505-31508 |
IN |
denotes |
for |
T18340 |
31509-31519 |
NN |
denotes |
importin-α |
T18341 |
31519-31520 |
. |
denotes |
. |
T18342 |
31521-31522 |
-LRB- |
denotes |
( |
T18343 |
31522-31523 |
NNP |
denotes |
A |
T18344 |
31523-31524 |
-RRB- |
denotes |
) |
T18345 |
31525-31534 |
JJ |
denotes |
schematic |
T18346 |
31535-31549 |
NN |
denotes |
representation |
T18347 |
31550-31552 |
IN |
denotes |
of |
T18348 |
31553-31556 |
DT |
denotes |
the |
T18349 |
31557-31559 |
IN |
denotes |
in |
T18350 |
31560-31565 |
NN |
denotes |
vitro |
T18351 |
31566-31573 |
JJ |
denotes |
binding |
T18352 |
31574-31585 |
NN |
denotes |
competition |
T18353 |
31586-31591 |
NN |
denotes |
assay |
T18354 |
31591-31592 |
. |
denotes |
. |
T18355 |
31593-31594 |
-LRB- |
denotes |
( |
T18356 |
31594-31595 |
NNP |
denotes |
B |
T18357 |
31595-31596 |
-RRB- |
denotes |
) |
T18358 |
31597-31599 |
NNP |
denotes |
GR |
T18359 |
31600-31608 |
VBD |
denotes |
isolated |
T18360 |
31609-31613 |
IN |
denotes |
from |
T18361 |
31614-31616 |
NNP |
denotes |
FP |
T18362 |
31617-31618 |
-LRB- |
denotes |
( |
T18363 |
31618-31620 |
CD |
denotes |
10 |
T18364 |
31620-31621 |
NN |
denotes |
− |
T18365 |
31621-31622 |
CD |
denotes |
8 |
T18366 |
31623-31624 |
NNP |
denotes |
M |
T18367 |
31624-31625 |
-RRB- |
denotes |
) |
T18368 |
31626-31636 |
VBD |
denotes |
stimulated |
T18369 |
31637-31642 |
NNS |
denotes |
cells |
T18370 |
31643-31651 |
VBZ |
denotes |
enhances |
T18371 |
31652-31654 |
NNP |
denotes |
GR |
T18372 |
31655-31665 |
JJ |
denotes |
importin-α |
T18373 |
31666-31673 |
JJ |
denotes |
binding |
T18374 |
31674-31676 |
IN |
denotes |
in |
T18375 |
31677-31680 |
DT |
denotes |
the |
T18376 |
31681-31689 |
NN |
denotes |
presence |
T18377 |
31690-31691 |
-LRB- |
denotes |
( |
T18378 |
31691-31692 |
FW |
denotes |
• |
T18379 |
31692-31693 |
-RRB- |
denotes |
) |
T18380 |
31694-31697 |
CC |
denotes |
and |
T18381 |
31698-31705 |
NN |
denotes |
absence |
T18382 |
31706-31707 |
-LRB- |
denotes |
( |
T18383 |
31707-31708 |
FW |
denotes |
▪ |
T18384 |
31708-31709 |
-RRB- |
denotes |
) |
T18385 |
31710-31712 |
IN |
denotes |
of |
T18386 |
31713-31722 |
VBN |
denotes |
activated |
T18387 |
31723-31729 |
NNP |
denotes |
GATA-3 |
T18388 |
31729-31730 |
. |
denotes |
. |
T18389 |
31731-31732 |
SYM |
denotes |
* |
T18390 |
31733-31734 |
NN |
denotes |
p |
T18391 |
31734-31735 |
NN |
denotes |
< |
T18392 |
31735-31739 |
CD |
denotes |
0.05 |
T18393 |
31740-31748 |
VBN |
denotes |
compared |
T18394 |
31749-31751 |
TO |
denotes |
to |
T18395 |
31752-31754 |
DT |
denotes |
no |
T18396 |
31755-31764 |
VBN |
denotes |
activated |
T18397 |
31765-31767 |
NNP |
denotes |
GR |
T18398 |
31767-31768 |
. |
denotes |
. |
T18399 |
31769-31770 |
-LRB- |
denotes |
( |
T18400 |
31770-31771 |
$ |
denotes |
C |
T18401 |
31771-31772 |
-RRB- |
denotes |
) |
T18402 |
31773-31779 |
JJ |
denotes |
GATA-3 |
T18403 |
31780-31788 |
VBN |
denotes |
isolated |
T18404 |
31789-31793 |
IN |
denotes |
from |
T18405 |
31794-31802 |
JJ |
denotes |
anti-CD3 |
T18406 |
31802-31803 |
NN |
denotes |
/ |
T18407 |
31803-31807 |
CD |
denotes |
CD28 |
T18408 |
31808-31818 |
VBD |
denotes |
stimulated |
T18409 |
31819-31824 |
NNS |
denotes |
cells |
T18410 |
31825-31829 |
VBZ |
denotes |
does |
T18411 |
31830-31833 |
RB |
denotes |
not |
T18412 |
31834-31843 |
VB |
denotes |
attenuate |
T18413 |
31844-31846 |
NNP |
denotes |
GR |
T18414 |
31847-31857 |
JJ |
denotes |
importin-α |
T18415 |
31858-31869 |
NN |
denotes |
association |
T18416 |
31869-31870 |
. |
denotes |
. |
T18417 |
31871-31872 |
SYM |
denotes |
* |
T18418 |
31872-31873 |
NN |
denotes |
p |
T18419 |
31873-31874 |
NN |
denotes |
< |
T18420 |
31874-31878 |
CD |
denotes |
0.05 |
T18421 |
31879-31887 |
VBN |
denotes |
compared |
T18422 |
31888-31890 |
TO |
denotes |
to |
T18423 |
31891-31898 |
VB |
denotes |
control |
T18424 |
31898-31899 |
. |
denotes |
. |
T18425 |
31900-31901 |
-LRB- |
denotes |
( |
T18426 |
31901-31902 |
NNP |
denotes |
D |
T18427 |
31902-31903 |
-RRB- |
denotes |
) |
T18428 |
31904-31913 |
NNP |
denotes |
Activated |
T18429 |
31914-31916 |
NNP |
denotes |
GR |
T18430 |
31917-31923 |
VBZ |
denotes |
blocks |
T18431 |
31924-31927 |
DT |
denotes |
the |
T18432 |
31928-31935 |
NN |
denotes |
ability |
T18433 |
31936-31938 |
IN |
denotes |
of |
T18434 |
31939-31947 |
JJ |
denotes |
purified |
T18435 |
31948-31962 |
JJ |
denotes |
phospho-GATA-3 |
T18436 |
31963-31971 |
VBN |
denotes |
isolated |
T18437 |
31972-31976 |
IN |
denotes |
from |
T18438 |
31977-31985 |
JJ |
denotes |
anti-CD3 |
T18439 |
31985-31986 |
NN |
denotes |
/ |
T18440 |
31986-31990 |
CD |
denotes |
CD28 |
T18441 |
31991-32001 |
VBD |
denotes |
stimulated |
T18442 |
32002-32007 |
NNS |
denotes |
cells |
T18443 |
32008-32019 |
VBG |
denotes |
interacting |
T18444 |
32020-32024 |
IN |
denotes |
with |
T18445 |
32025-32036 |
JJ |
denotes |
immobilised |
T18446 |
32037-32047 |
NN |
denotes |
importin-α |
T18447 |
32048-32050 |
IN |
denotes |
in |
T18448 |
32051-32053 |
DT |
denotes |
an |
T18449 |
32054-32056 |
IN |
denotes |
in |
T18450 |
32057-32062 |
NN |
denotes |
vitro |
T18451 |
32063-32070 |
JJ |
denotes |
binding |
T18452 |
32071-32076 |
NN |
denotes |
assay |
T18453 |
32076-32077 |
. |
denotes |
. |
T18454 |
32078-32079 |
SYM |
denotes |
* |
T18455 |
32079-32080 |
NN |
denotes |
p |
T18456 |
32080-32081 |
NN |
denotes |
< |
T18457 |
32081-32085 |
CD |
denotes |
0.05 |
T18458 |
32086-32094 |
VBN |
denotes |
compared |
T18459 |
32095-32097 |
TO |
denotes |
to |
T18460 |
32098-32104 |
JJ |
denotes |
GATA-3 |
T18461 |
32105-32113 |
VBN |
denotes |
isolated |
T18462 |
32114-32118 |
IN |
denotes |
from |
T18463 |
32119-32131 |
JJ |
denotes |
unstimulated |
T18464 |
32132-32137 |
NNS |
denotes |
cells |
T18465 |
32137-32138 |
. |
denotes |
. |
T18466 |
32139-32142 |
JJ |
denotes |
# p |
T18467 |
32142-32143 |
NN |
denotes |
< |
T18468 |
32143-32147 |
CD |
denotes |
0.05 |
T18469 |
32148-32156 |
VBN |
denotes |
compared |
T18470 |
32157-32159 |
TO |
denotes |
to |
T18471 |
32160-32170 |
VBN |
denotes |
stimulated |
T18472 |
32171-32186 |
JJ |
denotes |
GATA-3-importin |
T18473 |
32187-32194 |
JJ |
denotes |
binding |
T18474 |
32194-32195 |
. |
denotes |
. |
T18475 |
32196-32197 |
-LRB- |
denotes |
( |
T18476 |
32197-32198 |
NNP |
denotes |
E |
T18477 |
32198-32199 |
-RRB- |
denotes |
) |
T18478 |
32200-32203 |
DT |
denotes |
The |
T18479 |
32204-32210 |
NN |
denotes |
effect |
T18480 |
32211-32213 |
IN |
denotes |
of |
T18481 |
32214-32223 |
VBN |
denotes |
activated |
T18482 |
32224-32225 |
-LRB- |
denotes |
( |
T18483 |
32225-32226 |
NN |
denotes |
• |
T18484 |
32226-32227 |
-RRB- |
denotes |
) |
T18485 |
32228-32234 |
CC |
denotes |
versus |
T18486 |
32235-32247 |
JJ |
denotes |
unstimulated |
T18487 |
32248-32249 |
-LRB- |
denotes |
( |
T18488 |
32249-32250 |
NN |
denotes |
○ |
T18489 |
32250-32251 |
-RRB- |
denotes |
) |
T18490 |
32252-32254 |
NN |
denotes |
GR |
T18491 |
32255-32257 |
IN |
denotes |
on |
T18492 |
32258-32269 |
NN |
denotes |
attenuation |
T18493 |
32270-32272 |
IN |
denotes |
of |
T18494 |
32273-32279 |
NNP |
denotes |
GATA-3 |
T18495 |
32280-32290 |
JJ |
denotes |
importin-α |
T18496 |
32291-32302 |
NN |
denotes |
association |
T18497 |
32303-32306 |
VBD |
denotes |
was |
T18498 |
32307-32330 |
JJ |
denotes |
concentration-dependent |
T18499 |
32330-32331 |
. |
denotes |
. |
T18500 |
32332-32333 |
SYM |
denotes |
* |
T18501 |
32333-32334 |
NN |
denotes |
p |
T18502 |
32334-32335 |
NN |
denotes |
< |
T18503 |
32335-32339 |
CD |
denotes |
0.05 |
T18504 |
32339-32340 |
, |
denotes |
, |
T18505 |
32341-32343 |
SYM |
denotes |
** |
T18506 |
32343-32344 |
FW |
denotes |
p |
T18507 |
32344-32345 |
FW |
denotes |
< |
T18508 |
32345-32349 |
CD |
denotes |
0.01 |
T18509 |
32350-32357 |
IN |
denotes |
between |
T18510 |
32358-32364 |
NNS |
denotes |
groups |
T18511 |
32364-32365 |
. |
denotes |
. |
T18512 |
32366-32369 |
DT |
denotes |
All |
T18513 |
32370-32377 |
NNS |
denotes |
results |
T18514 |
32378-32381 |
VBP |
denotes |
are |
T18515 |
32382-32391 |
VBN |
denotes |
expressed |
T18516 |
32392-32394 |
IN |
denotes |
as |
T18517 |
32395-32399 |
JJ |
denotes |
mean |
T18518 |
32399-32400 |
NN |
denotes |
± |
T18519 |
32400-32403 |
NNP |
denotes |
SEM |
T18520 |
32404-32406 |
IN |
denotes |
of |
T18521 |
32407-32412 |
CD |
denotes |
three |
T18522 |
32413-32424 |
JJ |
denotes |
independent |
T18523 |
32425-32436 |
NNS |
denotes |
experiments |
T18524 |
32437-32440 |
CC |
denotes |
and |
T18525 |
32441-32449 |
VBN |
denotes |
analysed |
T18526 |
32450-32452 |
IN |
denotes |
by |
T18527 |
32453-32458 |
NNP |
denotes |
ANOVA |
T18528 |
32459-32467 |
VBD |
denotes |
followed |
T18529 |
32468-32470 |
IN |
denotes |
by |
T18530 |
32471-32483 |
NNP |
denotes |
Newman-Keuls |
T18531 |
32484-32493 |
JJS |
denotes |
post-test |
T18532 |
32493-32494 |
. |
denotes |
. |
T10533 |
32497-32502 |
JJ |
denotes |
Other |
T10534 |
32503-32511 |
JJ |
denotes |
possible |
T10535 |
32512-32527 |
NNS |
denotes |
interpretations |
T10536 |
32528-32530 |
IN |
denotes |
of |
T10537 |
32531-32534 |
PRP$ |
denotes |
our |
T10538 |
32535-32542 |
NNS |
denotes |
results |
T10539 |
32543-32548 |
MD |
denotes |
could |
T10540 |
32549-32556 |
VB |
denotes |
include |
T10541 |
32557-32559 |
DT |
denotes |
an |
T10542 |
32560-32566 |
NN |
denotes |
effect |
T10543 |
32567-32569 |
IN |
denotes |
of |
T10544 |
32570-32572 |
NNP |
denotes |
FP |
T10545 |
32573-32575 |
IN |
denotes |
on |
T10546 |
32576-32582 |
NNP |
denotes |
GATA-3 |
T10547 |
32583-32590 |
JJ |
denotes |
nuclear |
T10548 |
32591-32597 |
NN |
denotes |
export |
T10549 |
32598-32604 |
CC |
denotes |
and/or |
T10550 |
32605-32616 |
NN |
denotes |
degradation |
T10551 |
32616-32617 |
. |
denotes |
. |
T10552 |
32618-32628 |
NNP |
denotes |
Leptomycin |
T10553 |
32629-32630 |
NNP |
denotes |
B |
T10554 |
32630-32631 |
, |
denotes |
, |
T10555 |
32632-32637 |
WDT |
denotes |
which |
T10556 |
32638-32646 |
VBZ |
denotes |
inhibits |
T10557 |
32647-32654 |
JJ |
denotes |
nuclear |
T10558 |
32655-32661 |
NN |
denotes |
export |
T10559 |
32661-32662 |
, |
denotes |
, |
T10560 |
32663-32666 |
VBD |
denotes |
did |
T10561 |
32667-32670 |
RB |
denotes |
not |
T10562 |
32671-32677 |
VB |
denotes |
affect |
T10563 |
32678-32681 |
DT |
denotes |
the |
T10564 |
32682-32689 |
NN |
denotes |
ability |
T10565 |
32690-32692 |
IN |
denotes |
of |
T10566 |
32693-32695 |
NNP |
denotes |
FP |
T10567 |
32696-32698 |
TO |
denotes |
to |
T10568 |
32699-32704 |
VB |
denotes |
block |
T10569 |
32705-32711 |
JJ |
denotes |
GATA-3 |
T10570 |
32712-32719 |
JJ |
denotes |
nuclear |
T10571 |
32720-32732 |
NN |
denotes |
localization |
T10572 |
32733-32734 |
-LRB- |
denotes |
( |
T10573 |
32734-32740 |
NN |
denotes |
Figure |
T10574 |
32741-32743 |
NN |
denotes |
5A |
T10575 |
32743-32744 |
-RRB- |
denotes |
) |
T10576 |
32744-32745 |
. |
denotes |
. |
T10577 |
32746-32758 |
RB |
denotes |
Additionally |
T10578 |
32758-32759 |
, |
denotes |
, |
T10579 |
32760-32762 |
NNP |
denotes |
FP |
T10580 |
32763-32766 |
VBD |
denotes |
had |
T10581 |
32767-32769 |
DT |
denotes |
no |
T10582 |
32770-32776 |
NN |
denotes |
effect |
T10583 |
32777-32779 |
IN |
denotes |
on |
T10584 |
32780-32785 |
JJ |
denotes |
whole |
T10585 |
32786-32790 |
NN |
denotes |
cell |
T10586 |
32791-32797 |
NN |
denotes |
GATA-3 |
T10587 |
32798-32808 |
NN |
denotes |
expression |
T10588 |
32809-32815 |
IN |
denotes |
during |
T10589 |
32816-32819 |
DT |
denotes |
the |
T10590 |
32820-32824 |
NN |
denotes |
time |
T10591 |
32825-32831 |
NN |
denotes |
course |
T10592 |
32832-32834 |
IN |
denotes |
of |
T10593 |
32835-32840 |
DT |
denotes |
these |
T10594 |
32841-32852 |
NNS |
denotes |
experiments |
T10595 |
32853-32854 |
-LRB- |
denotes |
( |
T10596 |
32854-32860 |
NN |
denotes |
Figure |
T10597 |
32861-32863 |
NN |
denotes |
5B |
T10598 |
32863-32864 |
-RRB- |
denotes |
) |
T10599 |
32864-32865 |
. |
denotes |
. |
T10600 |
32866-32869 |
CC |
denotes |
Nor |
T10601 |
32870-32873 |
VBD |
denotes |
did |
T10602 |
32874-32882 |
NN |
denotes |
addition |
T10603 |
32883-32885 |
IN |
denotes |
of |
T10604 |
32886-32888 |
NNP |
denotes |
FP |
T10605 |
32889-32899 |
JJ |
denotes |
subsequent |
T10606 |
32900-32902 |
TO |
denotes |
to |
T10607 |
32903-32911 |
JJ |
denotes |
anti-CD3 |
T10608 |
32911-32912 |
NN |
denotes |
/ |
T10609 |
32912-32916 |
CD |
denotes |
CD28 |
T10610 |
32917-32924 |
JJ |
denotes |
nuclear |
T10611 |
32925-32938 |
NN |
denotes |
translocation |
T10612 |
32939-32945 |
VB |
denotes |
affect |
T10613 |
32946-32952 |
JJ |
denotes |
GATA-3 |
T10614 |
32953-32960 |
JJ |
denotes |
nuclear |
T10615 |
32961-32970 |
NN |
denotes |
residency |
T10616 |
32971-32972 |
-LRB- |
denotes |
( |
T10617 |
32972-32978 |
NN |
denotes |
Figure |
T10618 |
32979-32981 |
NN |
denotes |
5C |
T10619 |
32981-32982 |
-RRB- |
denotes |
) |
T10620 |
32982-32983 |
, |
denotes |
, |
T10621 |
32984-32994 |
VBG |
denotes |
suggesting |
T10622 |
32995-32999 |
IN |
denotes |
that |
T10623 |
33000-33009 |
VBN |
denotes |
activated |
T10624 |
33010-33012 |
NNP |
denotes |
GR |
T10625 |
33013-33017 |
VBZ |
denotes |
does |
T10626 |
33018-33021 |
RB |
denotes |
not |
T10627 |
33022-33029 |
VB |
denotes |
enhance |
T10628 |
33030-33036 |
JJ |
denotes |
GATA-3 |
T10629 |
33037-33044 |
JJ |
denotes |
nuclear |
T10630 |
33045-33051 |
NN |
denotes |
export |
T10631 |
33051-33052 |
. |
denotes |
. |
T10632 |
33053-33060 |
RB |
denotes |
Finally |
T10633 |
33060-33061 |
, |
denotes |
, |
T10634 |
33062-33065 |
DT |
denotes |
the |
T10635 |
33066-33072 |
NN |
denotes |
effect |
T10636 |
33073-33075 |
IN |
denotes |
of |
T10637 |
33076-33078 |
NNP |
denotes |
FP |
T10638 |
33079-33081 |
IN |
denotes |
on |
T10639 |
33082-33088 |
NNP |
denotes |
GATA-3 |
T10640 |
33089-33096 |
JJ |
denotes |
nuclear |
T10641 |
33097-33103 |
NN |
denotes |
import |
T10642 |
33104-33107 |
VBD |
denotes |
was |
T10643 |
33108-33111 |
RB |
denotes |
not |
T10644 |
33112-33123 |
JJ |
denotes |
nonspecific |
T10645 |
33123-33124 |
, |
denotes |
, |
T10646 |
33125-33130 |
IN |
denotes |
since |
T10647 |
33131-33133 |
NNP |
denotes |
FP |
T10648 |
33134-33135 |
-LRB- |
denotes |
( |
T10649 |
33135-33137 |
CD |
denotes |
10 |
T10650 |
33137-33138 |
NN |
denotes |
− |
T10651 |
33138-33139 |
CD |
denotes |
8 |
T10652 |
33140-33141 |
NNP |
denotes |
M |
T10653 |
33141-33142 |
-RRB- |
denotes |
) |
T10654 |
33143-33146 |
VBD |
denotes |
had |
T10655 |
33147-33149 |
DT |
denotes |
no |
T10656 |
33150-33156 |
NN |
denotes |
effect |
T10657 |
33157-33159 |
IN |
denotes |
on |
T10658 |
33160-33163 |
CD |
denotes |
p65 |
T10659 |
33164-33171 |
JJ |
denotes |
nuclear |
T10660 |
33172-33185 |
NN |
denotes |
translocation |
T10661 |
33186-33194 |
VBN |
denotes |
measured |
T10662 |
33195-33197 |
IN |
denotes |
at |
T10663 |
33198-33200 |
CD |
denotes |
60 |
T10664 |
33201-33204 |
NN |
denotes |
min |
T10665 |
33205-33206 |
-LRB- |
denotes |
( |
T10666 |
33206-33212 |
NN |
denotes |
Figure |
T10667 |
33213-33215 |
CD |
denotes |
5D |
T10668 |
33215-33216 |
-RRB- |
denotes |
) |
T10669 |
33216-33217 |
. |
denotes |
. |
T18930 |
33262-33273 |
NNP |
denotes |
Fluticasone |
T18931 |
33274-33284 |
NN |
denotes |
propionate |
T18932 |
33285-33289 |
VBZ |
denotes |
does |
T18933 |
33290-33293 |
RB |
denotes |
not |
T18934 |
33294-33300 |
VB |
denotes |
affect |
T18935 |
33301-33307 |
JJ |
denotes |
GATA-3 |
T18936 |
33308-33315 |
JJ |
denotes |
nuclear |
T18937 |
33316-33322 |
NN |
denotes |
export |
T18938 |
33322-33323 |
. |
denotes |
. |
T18939 |
33324-33325 |
-LRB- |
denotes |
( |
T18940 |
33325-33326 |
NN |
denotes |
A |
T18941 |
33326-33327 |
-RRB- |
denotes |
) |
T18942 |
33328-33335 |
JJ |
denotes |
Western |
T18943 |
33336-33340 |
NN |
denotes |
blot |
T18944 |
33341-33349 |
NN |
denotes |
analysis |
T18945 |
33350-33357 |
VBG |
denotes |
showing |
T18946 |
33358-33362 |
IN |
denotes |
that |
T18947 |
33363-33366 |
DT |
denotes |
the |
T18948 |
33367-33374 |
JJ |
denotes |
nuclear |
T18949 |
33375-33381 |
NN |
denotes |
export |
T18950 |
33382-33391 |
NN |
denotes |
inhibitor |
T18951 |
33392-33402 |
NN |
denotes |
leptomycin |
T18952 |
33403-33404 |
NNP |
denotes |
B |
T18953 |
33405-33406 |
-LRB- |
denotes |
( |
T18954 |
33406-33407 |
CD |
denotes |
2 |
T18955 |
33408-33410 |
NNP |
denotes |
nM |
T18956 |
33410-33411 |
-RRB- |
denotes |
) |
T18957 |
33412-33416 |
VBZ |
denotes |
does |
T18958 |
33417-33420 |
RB |
denotes |
not |
T18959 |
33421-33427 |
VB |
denotes |
affect |
T18960 |
33428-33431 |
DT |
denotes |
the |
T18961 |
33432-33439 |
NN |
denotes |
ability |
T18962 |
33440-33442 |
IN |
denotes |
of |
T18963 |
33443-33445 |
NNP |
denotes |
FP |
T18964 |
33446-33447 |
-LRB- |
denotes |
( |
T18965 |
33447-33449 |
CD |
denotes |
10 |
T18966 |
33449-33450 |
NN |
denotes |
− |
T18967 |
33450-33451 |
CD |
denotes |
8 |
T18968 |
33452-33453 |
NNP |
denotes |
M |
T18969 |
33453-33454 |
-RRB- |
denotes |
) |
T18970 |
33455-33457 |
TO |
denotes |
to |
T18971 |
33458-33465 |
VB |
denotes |
prevent |
T18972 |
33466-33474 |
JJ |
denotes |
anti-CD3 |
T18973 |
33474-33475 |
NN |
denotes |
/ |
T18974 |
33475-33479 |
CD |
denotes |
CD28 |
T18975 |
33480-33490 |
VBD |
denotes |
stimulated |
T18976 |
33491-33497 |
JJ |
denotes |
GATA-3 |
T18977 |
33498-33505 |
JJ |
denotes |
nuclear |
T18978 |
33506-33518 |
NN |
denotes |
localization |
T18979 |
33519-33527 |
VBN |
denotes |
measured |
T18980 |
33528-33530 |
IN |
denotes |
at |
T18981 |
33531-33533 |
CD |
denotes |
60 |
T18982 |
33534-33537 |
NN |
denotes |
min |
T18983 |
33537-33538 |
. |
denotes |
. |
T18984 |
33539-33542 |
FW |
denotes |
*** |
T18985 |
33542-33543 |
FW |
denotes |
p |
T18986 |
33543-33544 |
FW |
denotes |
< |
T18987 |
33544-33549 |
CD |
denotes |
0.001 |
T18988 |
33550-33558 |
VBN |
denotes |
compared |
T18989 |
33559-33561 |
TO |
denotes |
to |
T18990 |
33562-33574 |
JJ |
denotes |
unstimulated |
T18991 |
33575-33580 |
NNS |
denotes |
cells |
T18992 |
33580-33581 |
, |
denotes |
, |
T18993 |
33582-33585 |
FW |
denotes |
### |
T19003 |
33631-33636 |
NNS |
denotes |
cells |
T19004 |
33636-33637 |
. |
denotes |
. |
T19005 |
33638-33639 |
-LRB- |
denotes |
( |
T19006 |
33639-33640 |
NNP |
denotes |
B |
T19007 |
33640-33641 |
-RRB- |
denotes |
) |
T19008 |
33642-33649 |
NNP |
denotes |
Western |
T19009 |
33650-33654 |
NN |
denotes |
blot |
T19010 |
33655-33663 |
NN |
denotes |
analysis |
T19011 |
33664-33671 |
VBG |
denotes |
showing |
T19012 |
33672-33676 |
IN |
denotes |
that |
T19013 |
33677-33679 |
NNP |
denotes |
FP |
T19014 |
33680-33681 |
-LRB- |
denotes |
( |
T19015 |
33681-33683 |
CD |
denotes |
10 |
T19016 |
33683-33684 |
NN |
denotes |
− |
T19017 |
33684-33685 |
CD |
denotes |
8 |
T19018 |
33686-33687 |
NNP |
denotes |
M |
T19019 |
33687-33688 |
-RRB- |
denotes |
) |
T19020 |
33689-33693 |
VBZ |
denotes |
does |
T19021 |
33694-33697 |
RB |
denotes |
not |
T19022 |
33698-33704 |
VB |
denotes |
affect |
T19023 |
33705-33715 |
JJ |
denotes |
whole-cell |
T19024 |
33716-33722 |
JJ |
denotes |
GATA-3 |
T19025 |
33723-33734 |
NN |
denotes |
degradation |
T19026 |
33735-33739 |
IN |
denotes |
over |
T19027 |
33740-33742 |
CD |
denotes |
17 |
T19028 |
33743-33745 |
NN |
denotes |
h. |
T19029 |
33746-33747 |
-LRB- |
denotes |
( |
T19030 |
33747-33748 |
NNP |
denotes |
C |
T19031 |
33748-33749 |
-RRB- |
denotes |
) |
T19032 |
33750-33760 |
JJ |
denotes |
GFP-tagged |
T19033 |
33761-33767 |
NN |
denotes |
GATA-3 |
T19034 |
33768-33770 |
VBZ |
denotes |
is |
T19035 |
33771-33784 |
VBN |
denotes |
overexpressed |
T19036 |
33785-33788 |
CC |
denotes |
and |
T19037 |
33789-33794 |
NNS |
denotes |
cells |
T19038 |
33795-33805 |
VBN |
denotes |
stimulated |
T19039 |
33806-33807 |
-LRB- |
denotes |
( |
T19040 |
33807-33808 |
NN |
denotes |
b |
T19041 |
33809-33810 |
NN |
denotes |
j |
T19042 |
33810-33811 |
-RRB- |
denotes |
) |
T19043 |
33812-33814 |
CC |
denotes |
or |
T19044 |
33815-33818 |
RB |
denotes |
not |
T19045 |
33819-33820 |
-LRB- |
denotes |
( |
T19046 |
33820-33821 |
DT |
denotes |
a |
T19047 |
33821-33822 |
-RRB- |
denotes |
) |
T19048 |
33823-33827 |
IN |
denotes |
with |
T19049 |
33828-33836 |
JJ |
denotes |
anti-CD3 |
T19050 |
33836-33837 |
NN |
denotes |
/ |
T19051 |
33837-33841 |
NNP |
denotes |
CD28 |
T19052 |
33841-33842 |
. |
denotes |
. |
T19053 |
33843-33846 |
DT |
denotes |
The |
T19054 |
33847-33853 |
NN |
denotes |
effect |
T19055 |
33854-33856 |
IN |
denotes |
of |
T19056 |
33857-33865 |
VBG |
denotes |
treating |
T19057 |
33866-33871 |
NNS |
denotes |
cells |
T19058 |
33872-33876 |
IN |
denotes |
with |
T19059 |
33877-33879 |
NNP |
denotes |
FP |
T19060 |
33880-33881 |
-LRB- |
denotes |
( |
T19061 |
33881-33883 |
CD |
denotes |
10 |
T19062 |
33883-33884 |
NN |
denotes |
− |
T19063 |
33884-33885 |
CD |
denotes |
8 |
T19064 |
33886-33887 |
NNP |
denotes |
M |
T19065 |
33887-33888 |
, |
denotes |
, |
T19066 |
33889-33890 |
SYM |
denotes |
f |
T19067 |
33891-33892 |
NN |
denotes |
j |
T19068 |
33892-33893 |
-RRB- |
denotes |
) |
T19069 |
33894-33899 |
IN |
denotes |
after |
T19070 |
33900-33902 |
CD |
denotes |
30 |
T19071 |
33903-33906 |
NN |
denotes |
min |
T19072 |
33907-33918 |
NN |
denotes |
stimulation |
T19073 |
33919-33923 |
IN |
denotes |
with |
T19074 |
33924-33932 |
JJ |
denotes |
anti-CD3 |
T19075 |
33932-33933 |
NN |
denotes |
/ |
T19076 |
33933-33937 |
NNP |
denotes |
CD28 |
T19077 |
33938-33940 |
VBZ |
denotes |
is |
T19078 |
33941-33945 |
RB |
denotes |
also |
T19079 |
33946-33951 |
VBN |
denotes |
shown |
T19080 |
33951-33952 |
. |
denotes |
. |
T19081 |
33953-33954 |
-LRB- |
denotes |
( |
T19082 |
33954-33955 |
NNP |
denotes |
D |
T19083 |
33955-33956 |
-RRB- |
denotes |
) |
T19084 |
33957-33959 |
NNP |
denotes |
FP |
T19085 |
33960-33961 |
-LRB- |
denotes |
( |
T19086 |
33961-33963 |
CD |
denotes |
10 |
T19087 |
33963-33964 |
NN |
denotes |
− |
T19088 |
33964-33965 |
CD |
denotes |
8 |
T19089 |
33966-33967 |
NNP |
denotes |
M |
T19090 |
33967-33968 |
-RRB- |
denotes |
) |
T19091 |
33969-33973 |
VBZ |
denotes |
does |
T19092 |
33974-33977 |
RB |
denotes |
not |
T19093 |
33978-33985 |
VB |
denotes |
prevent |
T19094 |
33986-33994 |
JJ |
denotes |
anti-CD3 |
T19095 |
33994-33995 |
NN |
denotes |
/ |
T19096 |
33995-33999 |
CD |
denotes |
CD28 |
T19097 |
34000-34010 |
VBD |
denotes |
stimulated |
T19098 |
34011-34014 |
CD |
denotes |
p65 |
T19099 |
34015-34022 |
JJ |
denotes |
nuclear |
T19100 |
34023-34036 |
NN |
denotes |
translocation |
T19101 |
34037-34039 |
IN |
denotes |
at |
T19102 |
34040-34042 |
CD |
denotes |
60 |
T19103 |
34043-34046 |
NN |
denotes |
min |
T19104 |
34047-34052 |
IN |
denotes |
after |
T19105 |
34053-34064 |
NN |
denotes |
stimulation |
T19106 |
34064-34065 |
. |
denotes |
. |
T19107 |
34066-34068 |
SYM |
denotes |
** |
T19108 |
34068-34069 |
FW |
denotes |
p |
T19109 |
34069-34070 |
FW |
denotes |
< |
T19110 |
34070-34074 |
CD |
denotes |
0.01 |
T19111 |
34075-34083 |
VBN |
denotes |
compared |
T19112 |
34084-34086 |
TO |
denotes |
to |
T19113 |
34087-34099 |
JJ |
denotes |
unstimulated |
T19114 |
34100-34105 |
NNS |
denotes |
cells |
T19115 |
34105-34106 |
. |
denotes |
. |
T19116 |
34107-34110 |
DT |
denotes |
All |
T19117 |
34111-34118 |
NNS |
denotes |
results |
T19118 |
34119-34122 |
VBP |
denotes |
are |
T19119 |
34123-34137 |
NN |
denotes |
representative |
T19120 |
34138-34140 |
IN |
denotes |
of |
T19121 |
34141-34143 |
IN |
denotes |
at |
T19122 |
34144-34149 |
JJS |
denotes |
least |
T19123 |
34150-34154 |
CD |
denotes |
four |
T19124 |
34155-34166 |
JJ |
denotes |
independent |
T19125 |
34167-34178 |
NNS |
denotes |
experiments |
T19126 |
34179-34182 |
CC |
denotes |
and |
T19127 |
34183-34186 |
VBP |
denotes |
are |
T19128 |
34187-34192 |
VBN |
denotes |
shown |
T19129 |
34193-34195 |
IN |
denotes |
as |
T19130 |
34196-34200 |
JJ |
denotes |
mean |
T19131 |
34200-34201 |
NN |
denotes |
± |
T19132 |
34201-34204 |
NNP |
denotes |
SEM |
T19133 |
34204-34205 |
. |
denotes |
. |
T19134 |
34206-34213 |
NNS |
denotes |
Results |
T19135 |
34214-34218 |
VBD |
denotes |
were |
T19136 |
34219-34227 |
VBN |
denotes |
analysed |
T19137 |
34228-34230 |
IN |
denotes |
by |
T19138 |
34231-34236 |
NNP |
denotes |
ANOVA |
T19139 |
34237-34245 |
VBD |
denotes |
followed |
T19140 |
34246-34248 |
IN |
denotes |
by |
T19141 |
34249-34261 |
NNP |
denotes |
Newman-Keuls |
T19142 |
34262-34266 |
NN |
denotes |
test |
T19143 |
34266-34267 |
. |
denotes |
. |
T11922 |
34269-34272 |
DT |
denotes |
The |
T11923 |
34273-34283 |
NNP |
denotes |
Inhibitory |
T11924 |
34284-34290 |
NN |
denotes |
Effect |
T11925 |
34291-34293 |
IN |
denotes |
of |
T11926 |
34294-34309 |
NNS |
denotes |
Corticosteroids |
T11927 |
34310-34312 |
IN |
denotes |
on |
T11928 |
34313-34319 |
NNP |
denotes |
GATA-3 |
T11929 |
34320-34327 |
NNP |
denotes |
Nuclear |
T11930 |
34328-34340 |
NNP |
denotes |
Localization |
T11931 |
34341-34343 |
IN |
denotes |
in |
T11932 |
34344-34351 |
JJ |
denotes |
Primary |
T11933 |
34352-34353 |
NNP |
denotes |
T |
T11934 |
34354-34365 |
NNP |
denotes |
Lymphocytes |
T11935 |
34366-34368 |
NNP |
denotes |
Ex |
T11936 |
34369-34373 |
NNP |
denotes |
Vivo |
T11937 |
34374-34377 |
CC |
denotes |
and |
T11938 |
34378-34380 |
IN |
denotes |
In |
T11939 |
34381-34385 |
NNP |
denotes |
Vivo |
T11940 |
34386-34395 |
NNP |
denotes |
Treatment |
T11941 |
34396-34400 |
IN |
denotes |
with |
T11942 |
34401-34403 |
NNP |
denotes |
FP |
T11943 |
34404-34406 |
FW |
denotes |
ex |
T11944 |
34407-34411 |
FW |
denotes |
vivo |
T11945 |
34412-34424 |
VBD |
denotes |
demonstrated |
T11946 |
34425-34426 |
DT |
denotes |
a |
T11947 |
34427-34450 |
JJ |
denotes |
concentration-dependent |
T11948 |
34451-34459 |
NN |
denotes |
decrease |
T11949 |
34460-34462 |
IN |
denotes |
in |
T11950 |
34463-34466 |
DT |
denotes |
the |
T11951 |
34467-34473 |
JJ |
denotes |
direct |
T11952 |
34474-34485 |
NN |
denotes |
interaction |
T11953 |
34486-34493 |
IN |
denotes |
between |
T11954 |
34494-34508 |
JJ |
denotes |
phospho-GATA-3 |
T11955 |
34509-34512 |
CC |
denotes |
and |
T11956 |
34513-34523 |
JJ |
denotes |
importin-α |
T11957 |
34524-34526 |
IN |
denotes |
in |
T11958 |
34527-34532 |
NNS |
denotes |
PBMCs |
T11959 |
34533-34537 |
IN |
denotes |
from |
T11960 |
34538-34546 |
NNS |
denotes |
patients |
T11961 |
34547-34551 |
IN |
denotes |
with |
T11962 |
34552-34558 |
NN |
denotes |
asthma |
T11963 |
34559-34560 |
-LRB- |
denotes |
( |
T11964 |
34560-34566 |
NN |
denotes |
Figure |
T11965 |
34567-34569 |
NN |
denotes |
6A |
T11966 |
34570-34573 |
CC |
denotes |
and |
T11967 |
34574-34576 |
NN |
denotes |
6B |
T11968 |
34576-34577 |
-RRB- |
denotes |
) |
T11969 |
34577-34578 |
, |
denotes |
, |
T11970 |
34579-34584 |
WDT |
denotes |
which |
T11971 |
34585-34588 |
VBD |
denotes |
was |
T11972 |
34589-34602 |
RB |
denotes |
significantly |
T11973 |
34603-34612 |
VBN |
denotes |
inhibited |
T11974 |
34613-34615 |
IN |
denotes |
at |
T11975 |
34616-34618 |
CD |
denotes |
10 |
T11976 |
34618-34619 |
CD |
denotes |
− |
T11977 |
34619-34621 |
CD |
denotes |
12 |
T11978 |
34622-34623 |
NNP |
denotes |
M |
T11979 |
34624-34626 |
NNP |
denotes |
FP |
T11980 |
34627-34628 |
-LRB- |
denotes |
( |
T11981 |
34628-34629 |
FW |
denotes |
p |
T11982 |
34629-34630 |
FW |
denotes |
< |
T11983 |
34630-34635 |
CD |
denotes |
0.001 |
T11984 |
34635-34636 |
, |
denotes |
, |
T11985 |
34637-34642 |
NNP |
denotes |
ANOVA |
T11986 |
34643-34646 |
CC |
denotes |
and |
T11987 |
34647-34659 |
NNP |
denotes |
Newman-Keuls |
T11988 |
34660-34664 |
NN |
denotes |
test |
T11989 |
34664-34665 |
-RRB- |
denotes |
) |
T11990 |
34666-34669 |
CC |
denotes |
and |
T11991 |
34670-34680 |
RB |
denotes |
completely |
T11992 |
34681-34691 |
VBN |
denotes |
attenuated |
T11993 |
34692-34694 |
IN |
denotes |
by |
T11994 |
34695-34697 |
CD |
denotes |
10 |
T11995 |
34697-34698 |
NN |
denotes |
− |
T11996 |
34698-34699 |
CD |
denotes |
8 |
T11997 |
34700-34701 |
NNP |
denotes |
M |
T11998 |
34702-34704 |
NNP |
denotes |
FP |
T11999 |
34705-34706 |
-LRB- |
denotes |
( |
T12000 |
34706-34707 |
FW |
denotes |
p |
T12001 |
34707-34708 |
FW |
denotes |
< |
T12002 |
34708-34713 |
CD |
denotes |
0.001 |
T12003 |
34713-34714 |
, |
denotes |
, |
T12004 |
34715-34720 |
NNP |
denotes |
ANOVA |
T12005 |
34721-34724 |
CC |
denotes |
and |
T12006 |
34725-34737 |
NNP |
denotes |
Newman-Keuls |
T12007 |
34738-34742 |
NN |
denotes |
test |
T12008 |
34742-34743 |
-RRB- |
denotes |
) |
T12009 |
34743-34744 |
. |
denotes |
. |
T19430 |
34789-34800 |
NNP |
denotes |
Fluticasone |
T19431 |
34801-34811 |
NN |
denotes |
propionate |
T19432 |
34812-34819 |
VBZ |
denotes |
impairs |
T19433 |
34820-34826 |
JJ |
denotes |
GATA-3 |
T19434 |
34827-34838 |
NN |
denotes |
interaction |
T19435 |
34839-34843 |
IN |
denotes |
with |
T19436 |
34844-34854 |
JJ |
denotes |
importin-α |
T19437 |
34855-34858 |
CC |
denotes |
and |
T19438 |
34859-34865 |
JJ |
denotes |
GATA-3 |
T19439 |
34866-34873 |
JJ |
denotes |
nuclear |
T19440 |
34874-34886 |
NN |
denotes |
localization |
T19441 |
34887-34889 |
IN |
denotes |
in |
T19442 |
34890-34894 |
NN |
denotes |
vivo |
T19443 |
34895-34898 |
CC |
denotes |
and |
T19444 |
34899-34901 |
FW |
denotes |
ex |
T19445 |
34902-34906 |
FW |
denotes |
vivo |
T19446 |
34906-34907 |
. |
denotes |
. |
T19447 |
34908-34909 |
-LRB- |
denotes |
( |
T19448 |
34909-34910 |
DT |
denotes |
A |
T19449 |
34911-34914 |
CC |
denotes |
and |
T19450 |
34915-34916 |
NNP |
denotes |
B |
T19451 |
34916-34917 |
-RRB- |
denotes |
) |
T19452 |
34918-34940 |
NN |
denotes |
Co-immunoprecipitation |
T19453 |
34941-34949 |
NN |
denotes |
analysis |
T19454 |
34950-34952 |
IN |
denotes |
of |
T19455 |
34953-34958 |
NNS |
denotes |
PBMCs |
T19456 |
34959-34963 |
IN |
denotes |
from |
T19457 |
34964-34977 |
JJ |
denotes |
steroid-naïve |
T19458 |
34978-34984 |
NN |
denotes |
asthma |
T19459 |
34985-34993 |
NNS |
denotes |
patients |
T19460 |
34994-35001 |
VBN |
denotes |
treated |
T19461 |
35002-35006 |
IN |
denotes |
with |
T19462 |
35007-35009 |
NNP |
denotes |
FP |
T19463 |
35010-35012 |
IN |
denotes |
in |
T19464 |
35013-35018 |
NN |
denotes |
vitro |
T19465 |
35019-35031 |
VBD |
denotes |
demonstrated |
T19466 |
35032-35040 |
VBN |
denotes |
impaired |
T19467 |
35041-35052 |
NN |
denotes |
interaction |
T19468 |
35053-35060 |
IN |
denotes |
between |
T19469 |
35061-35067 |
NNP |
denotes |
GATA-3 |
T19470 |
35068-35071 |
CC |
denotes |
and |
T19471 |
35072-35082 |
JJ |
denotes |
importin-α |
T19472 |
35083-35091 |
VBN |
denotes |
measured |
T19473 |
35092-35094 |
IN |
denotes |
at |
T19474 |
35095-35097 |
CD |
denotes |
60 |
T19475 |
35098-35101 |
NN |
denotes |
min |
T19476 |
35101-35102 |
. |
denotes |
. |
T19477 |
35103-35107 |
DT |
denotes |
Each |
T19478 |
35108-35111 |
NN |
denotes |
bar |
T19479 |
35112-35122 |
VBZ |
denotes |
represents |
T19480 |
35123-35126 |
DT |
denotes |
the |
T19481 |
35127-35131 |
JJ |
denotes |
mean |
T19482 |
35131-35132 |
NN |
denotes |
± |
T19483 |
35132-35135 |
NNP |
denotes |
SEM |
T19484 |
35136-35138 |
IN |
denotes |
of |
T19485 |
35139-35141 |
IN |
denotes |
at |
T19486 |
35142-35147 |
JJS |
denotes |
least |
T19487 |
35148-35153 |
CD |
denotes |
three |
T19488 |
35154-35165 |
JJ |
denotes |
independent |
T19489 |
35166-35177 |
NNS |
denotes |
experiments |
T19490 |
35177-35178 |
: |
denotes |
; |
T19491 |
35179-35182 |
FW |
denotes |
*** |
T19492 |
35183-35184 |
FW |
denotes |
p |
T19493 |
35184-35185 |
FW |
denotes |
< |
T19494 |
35185-35190 |
CD |
denotes |
0.001 |
T19495 |
35191-35199 |
VBN |
denotes |
compared |
T19496 |
35200-35204 |
IN |
denotes |
with |
T19497 |
35205-35212 |
NN |
denotes |
control |
T19498 |
35213-35215 |
IN |
denotes |
as |
T19499 |
35216-35226 |
VBN |
denotes |
determined |
T19500 |
35227-35229 |
IN |
denotes |
by |
T19501 |
35230-35248 |
NNP |
denotes |
ANOVA/Newman-Keuls |
T19502 |
35249-35257 |
NN |
denotes |
analysis |
T19503 |
35257-35258 |
. |
denotes |
. |
T19504 |
35259-35260 |
-LRB- |
denotes |
( |
T19505 |
35260-35261 |
NNP |
denotes |
C |
T19506 |
35262-35265 |
CC |
denotes |
and |
T19507 |
35266-35267 |
NNP |
denotes |
D |
T19508 |
35267-35268 |
-RRB- |
denotes |
) |
T19509 |
35269-35291 |
NN |
denotes |
Co-immunoprecipitation |
T19510 |
35292-35300 |
NNS |
denotes |
analyses |
T19511 |
35301-35303 |
IN |
denotes |
of |
T19512 |
35304-35309 |
NNS |
denotes |
PBMCs |
T19513 |
35310-35314 |
IN |
denotes |
from |
T19514 |
35315-35328 |
JJ |
denotes |
steroid-naïve |
T19515 |
35329-35335 |
NN |
denotes |
asthma |
T19516 |
35336-35344 |
NNS |
denotes |
patients |
T19517 |
35345-35352 |
VBN |
denotes |
treated |
T19518 |
35353-35357 |
IN |
denotes |
with |
T19519 |
35358-35365 |
JJ |
denotes |
inhaled |
T19520 |
35366-35368 |
NNP |
denotes |
FP |
T19521 |
35369-35370 |
-LRB- |
denotes |
( |
T19522 |
35370-35373 |
CD |
denotes |
500 |
T19523 |
35374-35376 |
NN |
denotes |
µg |
T19524 |
35377-35380 |
IN |
denotes |
via |
T19525 |
35381-35382 |
DT |
denotes |
a |
T19526 |
35383-35389 |
NN |
denotes |
spacer |
T19527 |
35389-35390 |
-RRB- |
denotes |
) |
T19528 |
35391-35393 |
IN |
denotes |
in |
T19529 |
35394-35398 |
NN |
denotes |
vivo |
T19530 |
35399-35411 |
VBD |
denotes |
demonstrated |
T19531 |
35412-35421 |
VBN |
denotes |
decreased |
T19532 |
35422-35433 |
NN |
denotes |
association |
T19533 |
35434-35441 |
IN |
denotes |
between |
T19534 |
35442-35448 |
NNP |
denotes |
GATA-3 |
T19535 |
35449-35452 |
CC |
denotes |
and |
T19536 |
35453-35463 |
JJ |
denotes |
importin-α |
T19537 |
35463-35464 |
. |
denotes |
. |
T19538 |
35465-35468 |
DT |
denotes |
The |
T19539 |
35469-35479 |
JJ |
denotes |
individual |
T19540 |
35480-35486 |
NNS |
denotes |
values |
T19541 |
35487-35490 |
IN |
denotes |
for |
T19542 |
35491-35495 |
DT |
denotes |
each |
T19543 |
35496-35505 |
NN |
denotes |
treatment |
T19544 |
35506-35509 |
VBP |
denotes |
are |
T19545 |
35510-35519 |
VBN |
denotes |
presented |
T19546 |
35520-35531 |
RB |
denotes |
graphically |
T19547 |
35531-35532 |
. |
denotes |
. |
T19548 |
35533-35534 |
-LRB- |
denotes |
( |
T19549 |
35534-35535 |
NNP |
denotes |
E |
T19550 |
35535-35536 |
-RRB- |
denotes |
) |
T19551 |
35537-35551 |
NNP |
denotes |
Representative |
T19552 |
35552-35559 |
NNP |
denotes |
Western |
T19553 |
35560-35564 |
NN |
denotes |
blot |
T19554 |
35565-35572 |
VBG |
denotes |
showing |
T19555 |
35573-35577 |
IN |
denotes |
that |
T19556 |
35578-35588 |
JJ |
denotes |
importin-α |
T19557 |
35589-35599 |
NN |
denotes |
expression |
T19558 |
35600-35603 |
VBD |
denotes |
was |
T19559 |
35604-35614 |
JJ |
denotes |
unaffected |
T19560 |
35615-35617 |
IN |
denotes |
by |
T19561 |
35618-35628 |
NN |
denotes |
inhalation |
T19562 |
35629-35631 |
IN |
denotes |
of |
T19563 |
35632-35634 |
NNP |
denotes |
FP |
T19564 |
35634-35635 |
. |
denotes |
. |
T19565 |
35636-35640 |
NNP |
denotes |
Blot |
T19566 |
35641-35643 |
VBZ |
denotes |
is |
T19567 |
35644-35658 |
NN |
denotes |
representative |
T19568 |
35659-35661 |
IN |
denotes |
of |
T19569 |
35662-35666 |
NNS |
denotes |
gels |
T19570 |
35667-35671 |
IN |
denotes |
from |
T19571 |
35672-35677 |
CD |
denotes |
three |
T19572 |
35678-35690 |
NNS |
denotes |
participants |
T19573 |
35690-35691 |
. |
denotes |
. |
T12010 |
35694-35697 |
PRP$ |
denotes |
Our |
T12011 |
35698-35706 |
JJ |
denotes |
previous |
T12012 |
35707-35708 |
NNP |
denotes |
T |
T12013 |
35709-35713 |
NN |
denotes |
cell |
T12014 |
35714-35718 |
NN |
denotes |
line |
T12015 |
35719-35726 |
NNS |
denotes |
studies |
T12016 |
35727-35736 |
VBD |
denotes |
indicated |
T12017 |
35737-35741 |
IN |
denotes |
that |
T12018 |
35742-35744 |
CD |
denotes |
10 |
T12019 |
35744-35745 |
CD |
denotes |
− |
T12020 |
35745-35747 |
CD |
denotes |
12 |
T12021 |
35748-35749 |
NNP |
denotes |
M |
T12022 |
35750-35752 |
NNP |
denotes |
FP |
T12023 |
35753-35763 |
VBZ |
denotes |
suppresses |
T12024 |
35764-35768 |
NN |
denotes |
IL-4 |
T12025 |
35769-35772 |
CC |
denotes |
and |
T12026 |
35773-35775 |
CD |
denotes |
-5 |
T12027 |
35776-35780 |
NN |
denotes |
gene |
T12028 |
35781-35791 |
NN |
denotes |
expression |
T12029 |
35792-35795 |
CC |
denotes |
and |
T12030 |
35796-35806 |
VBD |
denotes |
attenuated |
T12031 |
35807-35810 |
DT |
denotes |
the |
T12032 |
35811-35822 |
NN |
denotes |
interaction |
T12033 |
35823-35825 |
IN |
denotes |
of |
T12034 |
35826-35832 |
NN |
denotes |
GATA-3 |
T12035 |
35833-35837 |
IN |
denotes |
with |
T12036 |
35838-35848 |
JJ |
denotes |
importin-α |
T12037 |
35849-35850 |
-LRB- |
denotes |
( |
T12038 |
35850-35853 |
VB |
denotes |
see |
T12039 |
35854-35861 |
NNS |
denotes |
Figures |
T12040 |
35862-35864 |
CD |
denotes |
1D |
T12041 |
35865-35868 |
CC |
denotes |
and |
T12042 |
35869-35870 |
CD |
denotes |
2 |
T12043 |
35870-35871 |
-RRB- |
denotes |
) |
T12044 |
35871-35872 |
. |
denotes |
. |
T12045 |
35873-35877 |
DT |
denotes |
This |
T12046 |
35878-35891 |
NN |
denotes |
concentration |
T12047 |
35892-35894 |
VBZ |
denotes |
is |
T12048 |
35895-35900 |
JJ |
denotes |
close |
T12049 |
35901-35903 |
TO |
denotes |
to |
T12050 |
35904-35908 |
VB |
denotes |
peak |
T12051 |
35909-35915 |
NN |
denotes |
plasma |
T12052 |
35916-35922 |
NNS |
denotes |
levels |
T12053 |
35923-35931 |
VBN |
denotes |
obtained |
T12054 |
35932-35936 |
IN |
denotes |
from |
T12055 |
35937-35946 |
JJ |
denotes |
asthmatic |
T12056 |
35947-35955 |
NNS |
denotes |
patients |
T12057 |
35956-35963 |
VBN |
denotes |
treated |
T12058 |
35964-35968 |
IN |
denotes |
with |
T12059 |
35969-35976 |
JJ |
denotes |
inhaled |
T12060 |
35977-35979 |
NNP |
denotes |
FP |
T12061 |
35980-35981 |
-LRB- |
denotes |
( |
T12062 |
35981-35984 |
CD |
denotes |
500 |
T12063 |
35985-35987 |
NN |
denotes |
µg |
T12064 |
35987-35988 |
-RRB- |
denotes |
) |
T12065 |
35989-35990 |
NNP |
denotes |
[ |
T12066 |
35990-35992 |
CD |
denotes |
27 |
T12067 |
35992-35993 |
NNP |
denotes |
] |
T12068 |
35993-35994 |
. |
denotes |
. |
T12069 |
35995-36002 |
VBN |
denotes |
Inhaled |
T12070 |
36003-36005 |
NNP |
denotes |
FP |
T12071 |
36006-36007 |
-LRB- |
denotes |
( |
T12072 |
36007-36010 |
CD |
denotes |
500 |
T12073 |
36011-36013 |
NN |
denotes |
µg |
T12074 |
36013-36014 |
-RRB- |
denotes |
) |
T12075 |
36015-36024 |
NN |
denotes |
treatment |
T12076 |
36025-36027 |
IN |
denotes |
of |
T12077 |
36028-36033 |
CD |
denotes |
seven |
T12078 |
36034-36047 |
JJ |
denotes |
steroid-naive |
T12079 |
36048-36054 |
NN |
denotes |
asthma |
T12080 |
36055-36063 |
NNS |
denotes |
patients |
T12081 |
36064-36077 |
RB |
denotes |
significantly |
T12082 |
36078-36085 |
VBD |
denotes |
reduced |
T12083 |
36086-36092 |
NNP |
denotes |
GATA-3 |
T12084 |
36093-36103 |
JJ |
denotes |
importin-α |
T12085 |
36104-36115 |
NN |
denotes |
interaction |
T12086 |
36116-36118 |
IN |
denotes |
in |
T12087 |
36119-36123 |
NN |
denotes |
vivo |
T12088 |
36124-36126 |
IN |
denotes |
in |
T12089 |
36127-36128 |
DT |
denotes |
a |
T12090 |
36129-36143 |
JJ |
denotes |
time-dependent |
T12091 |
36144-36150 |
NN |
denotes |
manner |
T12092 |
36150-36151 |
. |
denotes |
. |
T12093 |
36152-36156 |
DT |
denotes |
This |
T12094 |
36157-36165 |
VBD |
denotes |
produced |
T12095 |
36166-36167 |
DT |
denotes |
a |
T12096 |
36168-36169 |
NN |
denotes |
> |
T12097 |
36169-36171 |
CD |
denotes |
90 |
T12098 |
36171-36172 |
NN |
denotes |
% |
T12099 |
36173-36181 |
NN |
denotes |
decrease |
T12100 |
36182-36184 |
IN |
denotes |
in |
T12101 |
36185-36191 |
NNP |
denotes |
GATA-3 |
T12102 |
36192-36202 |
JJ |
denotes |
importin-α |
T12103 |
36203-36214 |
NN |
denotes |
association |
T12104 |
36215-36217 |
IN |
denotes |
at |
T12105 |
36218-36219 |
CD |
denotes |
2 |
T12106 |
36220-36221 |
NN |
denotes |
h |
T12107 |
36222-36223 |
-LRB- |
denotes |
( |
T12108 |
36223-36229 |
JJ |
denotes |
median |
T12109 |
36230-36231 |
NNP |
denotes |
[ |
T12110 |
36231-36233 |
CD |
denotes |
95 |
T12111 |
36233-36234 |
NN |
denotes |
% |
T12112 |
36235-36237 |
NNP |
denotes |
CI |
T12113 |
36237-36238 |
NNP |
denotes |
] |
T12114 |
36238-36239 |
, |
denotes |
, |
T12115 |
36240-36246 |
CD |
denotes |
13,494 |
T12116 |
36247-36248 |
NNP |
denotes |
[ |
T12117 |
36248-36253 |
CD |
denotes |
6,828 |
T12118 |
36254-36260 |
CD |
denotes |
17,829 |
T12119 |
36260-36261 |
NNP |
denotes |
] |
T12120 |
36262-36268 |
CC |
denotes |
versus |
T12121 |
36269-36272 |
CD |
denotes |
879 |
T12122 |
36273-36274 |
JJ |
denotes |
[ |
T12123 |
36274-36277 |
CD |
denotes |
597 |
T12124 |
36278-36283 |
CD |
denotes |
1,165 |
T12125 |
36283-36284 |
NNP |
denotes |
] |
T12126 |
36284-36285 |
: |
denotes |
; |
T12127 |
36286-36287 |
VB |
denotes |
p |
T12128 |
36287-36288 |
RB |
denotes |
< |
T12129 |
36288-36292 |
CD |
denotes |
0.05 |
T12130 |
36293-36301 |
NNP |
denotes |
Friedman |
T12131 |
36301-36303 |
POS |
denotes |
's |
T12132 |
36304-36312 |
NN |
denotes |
analysis |
T12133 |
36312-36313 |
-RRB- |
denotes |
) |
T12134 |
36313-36314 |
. |
denotes |
. |
T12135 |
36315-36322 |
RB |
denotes |
However |
T12136 |
36322-36323 |
, |
denotes |
, |
T12137 |
36324-36328 |
DT |
denotes |
this |
T12138 |
36329-36332 |
VBD |
denotes |
did |
T12139 |
36333-36336 |
RB |
denotes |
not |
T12140 |
36337-36342 |
VB |
denotes |
reach |
T12141 |
36343-36355 |
NN |
denotes |
significance |
T12142 |
36356-36361 |
VBG |
denotes |
using |
T12143 |
36362-36370 |
NNP |
denotes |
Wilcoxon |
T12144 |
36370-36372 |
POS |
denotes |
's |
T12145 |
36373-36382 |
JJ |
denotes |
post-test |
T12146 |
36383-36391 |
NN |
denotes |
analysis |
T12147 |
36392-36393 |
-LRB- |
denotes |
( |
T12148 |
36393-36394 |
NNP |
denotes |
W |
T12149 |
36395-36396 |
SYM |
denotes |
= |
T12150 |
36397-36401 |
CD |
denotes |
6.00 |
T12151 |
36401-36402 |
-RRB- |
denotes |
) |
T12152 |
36403-36411 |
RB |
denotes |
probably |
T12153 |
36412-36415 |
JJ |
denotes |
due |
T12154 |
36416-36418 |
TO |
denotes |
to |
T12155 |
36419-36422 |
JJ |
denotes |
low |
T12156 |
36423-36430 |
NNS |
denotes |
numbers |
T12157 |
36431-36433 |
IN |
denotes |
of |
T12158 |
36434-36446 |
NNS |
denotes |
participants |
T12159 |
36446-36447 |
. |
denotes |
. |
T12160 |
36448-36455 |
JJ |
denotes |
Similar |
T12161 |
36456-36463 |
NNS |
denotes |
results |
T12162 |
36464-36468 |
VBD |
denotes |
were |
T12163 |
36469-36477 |
VBN |
denotes |
observed |
T12164 |
36478-36482 |
WRB |
denotes |
when |
T12165 |
36483-36489 |
NNP |
denotes |
GATA-3 |
T12166 |
36490-36500 |
JJ |
denotes |
importin-α |
T12167 |
36501-36512 |
NN |
denotes |
association |
T12168 |
36513-36516 |
VBD |
denotes |
was |
T12169 |
36517-36525 |
VBN |
denotes |
measured |
T12170 |
36526-36527 |
-LRB- |
denotes |
( |
T12171 |
36527-36533 |
NNP |
denotes |
Figure |
T12172 |
36534-36536 |
NNP |
denotes |
6C |
T12173 |
36537-36540 |
CC |
denotes |
and |
T12174 |
36541-36543 |
NNP |
denotes |
6D |
T12175 |
36543-36544 |
-RRB- |
denotes |
) |
T12176 |
36544-36545 |
. |
denotes |
. |
T12177 |
36546-36549 |
DT |
denotes |
The |
T12178 |
36550-36555 |
JJR |
denotes |
lower |
T12179 |
36556-36560 |
NN |
denotes |
dose |
T12180 |
36561-36563 |
IN |
denotes |
of |
T12181 |
36564-36566 |
NNP |
denotes |
FP |
T12182 |
36567-36568 |
-LRB- |
denotes |
( |
T12183 |
36568-36571 |
CD |
denotes |
100 |
T12184 |
36572-36574 |
NN |
denotes |
µg |
T12185 |
36574-36575 |
-RRB- |
denotes |
) |
T12186 |
36576-36579 |
VBD |
denotes |
was |
T12187 |
36580-36583 |
RB |
denotes |
not |
T12188 |
36584-36593 |
JJ |
denotes |
effective |
T12189 |
36593-36594 |
. |
denotes |
. |
T12190 |
36595-36598 |
DT |
denotes |
The |
T12191 |
36599-36609 |
JJ |
denotes |
attenuated |
T12192 |
36610-36621 |
NN |
denotes |
interaction |
T12193 |
36622-36624 |
IN |
denotes |
of |
T12194 |
36625-36631 |
NN |
denotes |
GATA-3 |
T12195 |
36632-36635 |
VBD |
denotes |
did |
T12196 |
36636-36639 |
RB |
denotes |
not |
T12197 |
36640-36646 |
VB |
denotes |
result |
T12198 |
36647-36651 |
IN |
denotes |
from |
T12199 |
36652-36655 |
DT |
denotes |
the |
T12200 |
36656-36665 |
JJ |
denotes |
defective |
T12201 |
36666-36675 |
NN |
denotes |
recycling |
T12202 |
36676-36678 |
IN |
denotes |
of |
T12203 |
36679-36689 |
NN |
denotes |
importin-α |
T12204 |
36689-36690 |
, |
denotes |
, |
T12205 |
36691-36693 |
IN |
denotes |
as |
T12206 |
36694-36695 |
DT |
denotes |
a |
T12207 |
36696-36707 |
JJ |
denotes |
significant |
T12208 |
36708-36716 |
NN |
denotes |
decrease |
T12209 |
36717-36719 |
IN |
denotes |
in |
T12210 |
36720-36723 |
DT |
denotes |
the |
T12211 |
36724-36733 |
NN |
denotes |
abundance |
T12212 |
36734-36736 |
IN |
denotes |
of |
T12213 |
36737-36747 |
NN |
denotes |
importin-α |
T12214 |
36748-36750 |
IN |
denotes |
in |
T12215 |
36751-36754 |
DT |
denotes |
the |
T12216 |
36755-36766 |
JJ |
denotes |
cytoplasmic |
T12217 |
36767-36771 |
NN |
denotes |
pool |
T12218 |
36772-36775 |
VBD |
denotes |
was |
T12219 |
36776-36779 |
RB |
denotes |
not |
T12220 |
36780-36788 |
VBN |
denotes |
detected |
T12221 |
36789-36790 |
-LRB- |
denotes |
( |
T12222 |
36790-36796 |
NN |
denotes |
Figure |
T12223 |
36797-36799 |
CD |
denotes |
6E |
T12224 |
36799-36800 |
-RRB- |
denotes |
) |
T12225 |
36800-36801 |
. |
denotes |
. |
T12226 |
36802-36804 |
PRP |
denotes |
We |
T12227 |
36805-36812 |
RB |
denotes |
further |
T12228 |
36813-36821 |
VBD |
denotes |
examined |
T12229 |
36822-36829 |
IN |
denotes |
whether |
T12230 |
36830-36837 |
JJ |
denotes |
inhaled |
T12231 |
36838-36840 |
NNP |
denotes |
FP |
T12232 |
36841-36846 |
MD |
denotes |
could |
T12233 |
36847-36853 |
VB |
denotes |
affect |
T12234 |
36854-36862 |
JJ |
denotes |
cellular |
T12235 |
36863-36875 |
NN |
denotes |
localization |
T12236 |
36876-36878 |
IN |
denotes |
of |
T12237 |
36879-36885 |
NN |
denotes |
GATA-3 |
T12238 |
36886-36888 |
IN |
denotes |
in |
T12239 |
36889-36899 |
JJ |
denotes |
peripheral |
T12240 |
36900-36905 |
NN |
denotes |
blood |
T12241 |
36906-36907 |
NNP |
denotes |
T |
T12242 |
36908-36913 |
NNS |
denotes |
cells |
T12243 |
36913-36914 |
. |
denotes |
. |
T12244 |
36915-36924 |
NNP |
denotes |
Treatment |
T12245 |
36925-36929 |
IN |
denotes |
with |
T12246 |
36930-36937 |
JJ |
denotes |
inhaled |
T12247 |
36938-36940 |
NNP |
denotes |
FP |
T12248 |
36941-36942 |
-LRB- |
denotes |
( |
T12249 |
36942-36945 |
CD |
denotes |
500 |
T12250 |
36946-36948 |
NN |
denotes |
µg |
T12251 |
36948-36949 |
-RRB- |
denotes |
) |
T12252 |
36950-36953 |
IN |
denotes |
for |
T12253 |
36954-36955 |
CD |
denotes |
2 |
T12254 |
36956-36957 |
NN |
denotes |
h |
T12255 |
36958-36971 |
RB |
denotes |
significantly |
T12256 |
36972-36981 |
VBD |
denotes |
increased |
T12257 |
36982-36984 |
NNP |
denotes |
GR |
T12258 |
36985-36992 |
JJ |
denotes |
nuclear |
T12259 |
36993-37006 |
NN |
denotes |
translocation |
T12260 |
37007-37008 |
-LRB- |
denotes |
( |
T12261 |
37008-37014 |
NN |
denotes |
Figure |
T12262 |
37015-37017 |
NN |
denotes |
7A |
T12263 |
37017-37018 |
-RRB- |
denotes |
) |
T12264 |
37019-37022 |
CC |
denotes |
and |
T12265 |
37023-37036 |
RB |
denotes |
concomitantly |
T12266 |
37037-37046 |
VBD |
denotes |
decreased |
T12267 |
37047-37050 |
DT |
denotes |
the |
T12268 |
37051-37057 |
NN |
denotes |
number |
T12269 |
37058-37060 |
IN |
denotes |
of |
T12270 |
37061-37068 |
JJ |
denotes |
nuclear |
T12271 |
37069-37075 |
JJ |
denotes |
GATA-3 |
T12272 |
37076-37090 |
JJ |
denotes |
immunoreactive |
T12273 |
37091-37101 |
JJ |
denotes |
peripheral |
T12274 |
37102-37107 |
NN |
denotes |
blood |
T12275 |
37108-37109 |
NNP |
denotes |
T |
T12276 |
37110-37115 |
NNS |
denotes |
cells |
T12277 |
37116-37117 |
-LRB- |
denotes |
( |
T12278 |
37117-37119 |
CD |
denotes |
37 |
T12279 |
37119-37120 |
NN |
denotes |
% |
T12280 |
37120-37121 |
CD |
denotes |
± |
T12281 |
37121-37124 |
CD |
denotes |
4.2 |
T12282 |
37124-37125 |
NN |
denotes |
% |
T12283 |
37126-37132 |
CC |
denotes |
versus |
T12284 |
37133-37137 |
CD |
denotes |
58.2 |
T12285 |
37137-37138 |
NN |
denotes |
% |
T12286 |
37138-37139 |
CD |
denotes |
± |
T12287 |
37139-37143 |
CD |
denotes |
4.95 |
T12288 |
37143-37144 |
NN |
denotes |
% |
T12289 |
37144-37145 |
, |
denotes |
, |
T12290 |
37146-37147 |
VBP |
denotes |
p |
T12291 |
37148-37149 |
SYM |
denotes |
= |
T12292 |
37150-37155 |
CD |
denotes |
0.016 |
T12293 |
37155-37156 |
, |
denotes |
, |
T12294 |
37157-37158 |
NNP |
denotes |
W |
T12295 |
37159-37160 |
SYM |
denotes |
= |
T12296 |
37161-37165 |
CD |
denotes |
28.0 |
T12297 |
37165-37166 |
, |
denotes |
, |
T12298 |
37167-37175 |
NNP |
denotes |
Wilcoxon |
T12299 |
37175-37177 |
POS |
denotes |
's |
T12300 |
37178-37182 |
NN |
denotes |
rank |
T12301 |
37183-37187 |
NN |
denotes |
test |
T12302 |
37187-37188 |
-RRB- |
denotes |
) |
T12303 |
37189-37197 |
VBN |
denotes |
compared |
T12304 |
37198-37202 |
IN |
denotes |
with |
T12305 |
37203-37210 |
NN |
denotes |
placebo |
T12306 |
37211-37213 |
IN |
denotes |
as |
T12307 |
37214-37222 |
VBN |
denotes |
measured |
T12308 |
37223-37225 |
IN |
denotes |
by |
T12309 |
37226-37245 |
NN |
denotes |
immunocytochemistry |
T12310 |
37246-37247 |
-LRB- |
denotes |
( |
T12311 |
37247-37253 |
NN |
denotes |
Figure |
T12312 |
37254-37256 |
NN |
denotes |
7A |
T12313 |
37257-37260 |
CC |
denotes |
and |
T12314 |
37261-37263 |
NN |
denotes |
7B |
T12315 |
37263-37264 |
-RRB- |
denotes |
) |
T12316 |
37264-37265 |
. |
denotes |
. |
T12317 |
37266-37270 |
DT |
denotes |
This |
T12318 |
37271-37274 |
VBD |
denotes |
was |
T12319 |
37275-37284 |
VBN |
denotes |
confirmed |
T12320 |
37285-37287 |
IN |
denotes |
by |
T12321 |
37288-37295 |
JJ |
denotes |
Western |
T12322 |
37296-37304 |
VBG |
denotes |
blotting |
T12323 |
37304-37305 |
, |
denotes |
, |
T12324 |
37306-37311 |
WDT |
denotes |
which |
T12325 |
37312-37316 |
RB |
denotes |
also |
T12326 |
37317-37326 |
VBD |
denotes |
indicated |
T12327 |
37327-37331 |
IN |
denotes |
that |
T12328 |
37332-37336 |
DT |
denotes |
this |
T12329 |
37337-37343 |
NN |
denotes |
effect |
T12330 |
37344-37347 |
VBD |
denotes |
was |
T12331 |
37348-37352 |
DT |
denotes |
both |
T12332 |
37353-37357 |
NN |
denotes |
time |
T12333 |
37357-37358 |
: |
denotes |
- |
T12334 |
37359-37362 |
CC |
denotes |
and |
T12335 |
37363-37377 |
JJ |
denotes |
dose-dependent |
T12336 |
37378-37379 |
-LRB- |
denotes |
( |
T12337 |
37379-37385 |
NNP |
denotes |
Figure |
T12338 |
37386-37388 |
NNP |
denotes |
7C |
T12339 |
37389-37392 |
CC |
denotes |
and |
T12340 |
37393-37395 |
NNP |
denotes |
7D |
T12341 |
37395-37396 |
-RRB- |
denotes |
) |
T12342 |
37396-37397 |
. |
denotes |
. |
T12343 |
37398-37402 |
RB |
denotes |
Thus |
T12344 |
37402-37403 |
, |
denotes |
, |
T12345 |
37404-37411 |
VBD |
denotes |
inhaled |
T12346 |
37412-37414 |
NNP |
denotes |
FP |
T12347 |
37415-37416 |
-LRB- |
denotes |
( |
T12348 |
37416-37419 |
CD |
denotes |
500 |
T12349 |
37420-37422 |
NN |
denotes |
µg |
T12350 |
37422-37423 |
-RRB- |
denotes |
) |
T12351 |
37424-37431 |
VBD |
denotes |
induced |
T12352 |
37432-37443 |
JJ |
denotes |
significant |
T12353 |
37444-37448 |
NN |
denotes |
loss |
T12354 |
37449-37451 |
IN |
denotes |
in |
T12355 |
37452-37459 |
JJ |
denotes |
nuclear |
T12356 |
37460-37466 |
NN |
denotes |
GATA-3 |
T12357 |
37467-37469 |
IN |
denotes |
at |
T12358 |
37470-37471 |
CD |
denotes |
2 |
T12359 |
37472-37473 |
NN |
denotes |
h |
T12360 |
37474-37475 |
-LRB- |
denotes |
( |
T12361 |
37475-37481 |
JJ |
denotes |
median |
T12362 |
37482-37483 |
NNP |
denotes |
[ |
T12363 |
37483-37485 |
CD |
denotes |
95 |
T12364 |
37485-37486 |
NN |
denotes |
% |
T12365 |
37487-37489 |
NNP |
denotes |
CI |
T12366 |
37489-37490 |
NNP |
denotes |
] |
T12367 |
37490-37491 |
, |
denotes |
, |
T12368 |
37492-37496 |
CD |
denotes |
0.40 |
T12369 |
37497-37498 |
NNP |
denotes |
[ |
T12370 |
37498-37502 |
CD |
denotes |
0.27 |
T12371 |
37503-37507 |
CD |
denotes |
0.53 |
T12372 |
37507-37508 |
NNP |
denotes |
] |
T12373 |
37509-37515 |
CC |
denotes |
versus |
T12374 |
37516-37520 |
CD |
denotes |
0.14 |
T12375 |
37521-37522 |
NNP |
denotes |
[ |
T12376 |
37522-37526 |
CD |
denotes |
0.11 |
T12377 |
37527-37531 |
CD |
denotes |
0.19 |
T12378 |
37531-37532 |
NNP |
denotes |
] |
T12379 |
37532-37533 |
, |
denotes |
, |
T12380 |
37534-37535 |
NN |
denotes |
p |
T12381 |
37535-37536 |
NN |
denotes |
< |
T12382 |
37536-37540 |
CD |
denotes |
0.05 |
T12383 |
37540-37541 |
, |
denotes |
, |
T12384 |
37542-37543 |
NNP |
denotes |
W |
T12385 |
37544-37545 |
SYM |
denotes |
= |
T12386 |
37546-37551 |
CD |
denotes |
21.00 |
T12387 |
37551-37552 |
, |
denotes |
, |
T12388 |
37553-37561 |
NNP |
denotes |
Wilcoxon |
T12389 |
37561-37563 |
POS |
denotes |
's |
T12390 |
37564-37568 |
NN |
denotes |
rank |
T12391 |
37569-37573 |
NN |
denotes |
test |
T12392 |
37573-37574 |
-RRB- |
denotes |
) |
T12393 |
37575-37576 |
-LRB- |
denotes |
( |
T12394 |
37576-37582 |
NN |
denotes |
Figure |
T12395 |
37583-37585 |
NN |
denotes |
7C |
T12396 |
37585-37586 |
-RRB- |
denotes |
) |
T12397 |
37587-37590 |
CC |
denotes |
and |
T12398 |
37591-37602 |
JJ |
denotes |
cytoplasmic |
T12399 |
37603-37609 |
NN |
denotes |
GATA-3 |
T12400 |
37610-37616 |
NNS |
denotes |
levels |
T12401 |
37617-37621 |
VBD |
denotes |
were |
T12402 |
37622-37630 |
VBN |
denotes |
enhanced |
T12403 |
37631-37633 |
IN |
denotes |
by |
T12404 |
37634-37641 |
JJ |
denotes |
inhaled |
T12405 |
37642-37644 |
NNP |
denotes |
FP |
T12406 |
37645-37647 |
IN |
denotes |
in |
T12407 |
37648-37649 |
DT |
denotes |
a |
T12408 |
37650-37664 |
JJ |
denotes |
dose-dependent |
T12409 |
37665-37671 |
NN |
denotes |
manner |
T12410 |
37672-37673 |
-LRB- |
denotes |
( |
T12411 |
37673-37679 |
JJ |
denotes |
median |
T12412 |
37680-37681 |
NNP |
denotes |
[ |
T12413 |
37681-37683 |
CD |
denotes |
95 |
T12414 |
37683-37684 |
NN |
denotes |
% |
T12415 |
37685-37687 |
NNP |
denotes |
CI |
T12416 |
37687-37688 |
NNP |
denotes |
] |
T12417 |
37688-37689 |
, |
denotes |
, |
T12418 |
37690-37696 |
CD |
denotes |
0.0032 |
T12419 |
37697-37698 |
NNP |
denotes |
[ |
T12420 |
37698-37704 |
CD |
denotes |
0.0026 |
T12421 |
37705-37711 |
CD |
denotes |
0.0039 |
T12422 |
37711-37712 |
NNP |
denotes |
] |
T12423 |
37713-37719 |
CC |
denotes |
versus |
T12424 |
37720-37725 |
CD |
denotes |
0.658 |
T12425 |
37726-37727 |
NNP |
denotes |
[ |
T12426 |
37727-37732 |
CD |
denotes |
0.592 |
T12427 |
37733-37738 |
CD |
denotes |
0.720 |
T12428 |
37738-37739 |
NNP |
denotes |
] |
T12429 |
37739-37740 |
, |
denotes |
, |
T12430 |
37741-37742 |
NN |
denotes |
p |
T12431 |
37742-37743 |
NN |
denotes |
< |
T12432 |
37743-37747 |
CD |
denotes |
0.05 |
T12433 |
37747-37748 |
, |
denotes |
, |
T12434 |
37749-37750 |
NNP |
denotes |
W |
T12435 |
37751-37752 |
SYM |
denotes |
= |
T12436 |
37753-37754 |
FW |
denotes |
− |
T12437 |
37754-37759 |
CD |
denotes |
21.00 |
T12438 |
37759-37760 |
, |
denotes |
, |
T12439 |
37761-37769 |
NNP |
denotes |
Wilcoxon |
T12440 |
37769-37771 |
POS |
denotes |
's |
T12441 |
37772-37776 |
NN |
denotes |
rank |
T12442 |
37777-37781 |
NN |
denotes |
test |
T12443 |
37781-37782 |
-RRB- |
denotes |
) |
T12444 |
37783-37784 |
-LRB- |
denotes |
( |
T12445 |
37784-37790 |
NNP |
denotes |
Figure |
T12446 |
37791-37793 |
NNP |
denotes |
7D |
T12447 |
37793-37794 |
-RRB- |
denotes |
) |
T12448 |
37794-37795 |
. |
denotes |
. |
T12449 |
37796-37798 |
IN |
denotes |
In |
T12450 |
37799-37807 |
NN |
denotes |
addition |
T12451 |
37807-37808 |
, |
denotes |
, |
T12452 |
37809-37811 |
NNP |
denotes |
FP |
T12453 |
37812-37813 |
-LRB- |
denotes |
( |
T12454 |
37813-37816 |
CD |
denotes |
500 |
T12455 |
37817-37819 |
NN |
denotes |
µg |
T12456 |
37819-37820 |
-RRB- |
denotes |
) |
T12457 |
37821-37830 |
VBD |
denotes |
inhibited |
T12458 |
37831-37834 |
CD |
denotes |
p38 |
T12459 |
37835-37839 |
NNP |
denotes |
MAPK |
T12460 |
37840-37855 |
NN |
denotes |
phosphorylation |
T12461 |
37856-37858 |
IN |
denotes |
in |
T12462 |
37859-37866 |
JJ |
denotes |
primary |
T12463 |
37867-37868 |
NNP |
denotes |
T |
T12464 |
37869-37874 |
NNS |
denotes |
cells |
T12465 |
37875-37877 |
IN |
denotes |
in |
T12466 |
37878-37882 |
NN |
denotes |
vivo |
T12467 |
37883-37885 |
IN |
denotes |
at |
T12468 |
37886-37887 |
CD |
denotes |
2 |
T12469 |
37888-37889 |
NN |
denotes |
h |
T12470 |
37890-37892 |
IN |
denotes |
in |
T12471 |
37893-37900 |
NNS |
denotes |
samples |
T12472 |
37901-37905 |
IN |
denotes |
from |
T12473 |
37906-37909 |
CD |
denotes |
two |
T12474 |
37910-37918 |
NNS |
denotes |
patients |
T12475 |
37919-37920 |
-LRB- |
denotes |
( |
T12476 |
37920-37926 |
NN |
denotes |
Figure |
T12477 |
37927-37929 |
CD |
denotes |
7E |
T12478 |
37929-37930 |
-RRB- |
denotes |
) |
T12479 |
37930-37931 |
. |
denotes |
. |
T19983 |
37976-37983 |
VBN |
denotes |
Inhaled |
T19984 |
37984-37995 |
NN |
denotes |
fluticasone |
T19985 |
37996-38006 |
NN |
denotes |
propionate |
T19986 |
38007-38014 |
VBZ |
denotes |
impairs |
T19987 |
38015-38021 |
JJ |
denotes |
GATA-3 |
T19988 |
38022-38029 |
JJ |
denotes |
nuclear |
T19989 |
38030-38042 |
NN |
denotes |
localization |
T19990 |
38043-38045 |
IN |
denotes |
in |
T19991 |
38046-38051 |
NNP |
denotes |
PBMCs |
T19992 |
38051-38052 |
. |
denotes |
. |
T19993 |
38053-38054 |
-LRB- |
denotes |
( |
T19994 |
38054-38055 |
NNP |
denotes |
A |
T19995 |
38055-38056 |
-RRB- |
denotes |
) |
T19996 |
38057-38071 |
NNP |
denotes |
Representative |
T19997 |
38072-38091 |
NN |
denotes |
immunocytochemistry |
T19998 |
38092-38094 |
IN |
denotes |
of |
T19999 |
38095-38102 |
VBG |
denotes |
showing |
T20000 |
38103-38106 |
DT |
denotes |
the |
T20001 |
38107-38113 |
NN |
denotes |
effect |
T20002 |
38114-38116 |
IN |
denotes |
of |
T20003 |
38117-38124 |
JJ |
denotes |
inhaled |
T20004 |
38125-38127 |
NNP |
denotes |
FP |
T20005 |
38128-38129 |
-LRB- |
denotes |
( |
T20006 |
38129-38132 |
CD |
denotes |
500 |
T20007 |
38133-38135 |
NN |
denotes |
µg |
T20008 |
38135-38136 |
-RRB- |
denotes |
) |
T20009 |
38137-38139 |
IN |
denotes |
on |
T20010 |
38140-38142 |
NNP |
denotes |
GR |
T20011 |
38143-38146 |
CC |
denotes |
and |
T20012 |
38147-38153 |
NNP |
denotes |
GATA-3 |
T20013 |
38154-38161 |
JJ |
denotes |
nuclear |
T20014 |
38162-38174 |
NN |
denotes |
localisation |
T20015 |
38174-38175 |
. |
denotes |
. |
T20016 |
38176-38177 |
-LRB- |
denotes |
( |
T20017 |
38177-38178 |
NNP |
denotes |
B |
T20018 |
38178-38179 |
-RRB- |
denotes |
) |
T20019 |
38180-38187 |
NNP |
denotes |
Nuclear |
T20020 |
38188-38194 |
NNP |
denotes |
GATA-3 |
T20021 |
38195-38211 |
NN |
denotes |
immunoreactivity |
T20022 |
38212-38214 |
IN |
denotes |
in |
T20023 |
38215-38220 |
NNS |
denotes |
PBMCs |
T20024 |
38221-38225 |
IN |
denotes |
from |
T20025 |
38226-38231 |
CD |
denotes |
seven |
T20026 |
38232-38245 |
JJ |
denotes |
steroid-naïve |
T20027 |
38246-38252 |
NN |
denotes |
asthma |
T20028 |
38253-38261 |
NNS |
denotes |
patients |
T20029 |
38262-38263 |
CD |
denotes |
2 |
T20030 |
38264-38265 |
NN |
denotes |
h |
T20031 |
38266-38275 |
VBG |
denotes |
following |
T20032 |
38276-38283 |
JJ |
denotes |
inhaled |
T20033 |
38284-38286 |
NNP |
denotes |
FP |
T20034 |
38287-38296 |
NN |
denotes |
treatment |
T20035 |
38297-38298 |
-LRB- |
denotes |
( |
T20036 |
38298-38301 |
CD |
denotes |
100 |
T20037 |
38302-38304 |
CC |
denotes |
or |
T20038 |
38305-38308 |
CD |
denotes |
500 |
T20039 |
38309-38311 |
NN |
denotes |
µg |
T20040 |
38312-38315 |
IN |
denotes |
via |
T20041 |
38316-38322 |
NN |
denotes |
spacer |
T20042 |
38322-38323 |
-RRB- |
denotes |
) |
T20043 |
38323-38324 |
. |
denotes |
. |
T20044 |
38325-38328 |
DT |
denotes |
The |
T20045 |
38329-38335 |
NN |
denotes |
median |
T20046 |
38336-38339 |
CC |
denotes |
and |
T20047 |
38340-38353 |
JJ |
denotes |
interquartile |
T20048 |
38354-38360 |
NNS |
denotes |
ranges |
T20049 |
38361-38364 |
IN |
denotes |
for |
T20050 |
38365-38369 |
DT |
denotes |
each |
T20051 |
38370-38379 |
NN |
denotes |
treatment |
T20052 |
38380-38383 |
VBP |
denotes |
are |
T20053 |
38384-38393 |
VBN |
denotes |
presented |
T20054 |
38394-38396 |
IN |
denotes |
as |
T20055 |
38397-38398 |
DT |
denotes |
a |
T20056 |
38399-38415 |
NNS |
denotes |
box-and-whiskers |
T20057 |
38416-38420 |
NN |
denotes |
plot |
T20058 |
38421-38422 |
-LRB- |
denotes |
( |
T20059 |
38422-38423 |
FW |
denotes |
n |
T20060 |
38424-38425 |
SYM |
denotes |
= |
T20061 |
38426-38427 |
CD |
denotes |
7 |
T20062 |
38427-38428 |
-RRB- |
denotes |
) |
T20063 |
38428-38429 |
: |
denotes |
; |
T20064 |
38430-38431 |
SYM |
denotes |
* |
T20065 |
38432-38433 |
NN |
denotes |
p |
T20066 |
38433-38434 |
NN |
denotes |
< |
T20067 |
38434-38438 |
CD |
denotes |
0.05 |
T20068 |
38439-38447 |
NNP |
denotes |
Wilcoxon |
T20069 |
38447-38449 |
POS |
denotes |
's |
T20070 |
38450-38454 |
NN |
denotes |
rank |
T20071 |
38455-38459 |
NN |
denotes |
test |
T20072 |
38460-38468 |
VBN |
denotes |
compared |
T20073 |
38469-38473 |
IN |
denotes |
with |
T20074 |
38474-38481 |
NN |
denotes |
placebo |
T20075 |
38481-38482 |
. |
denotes |
. |
T20076 |
38483-38484 |
-LRB- |
denotes |
( |
T20077 |
38484-38485 |
NNP |
denotes |
C |
T20078 |
38485-38486 |
-RRB- |
denotes |
) |
T20079 |
38487-38501 |
NNP |
denotes |
Immunoblotting |
T20080 |
38502-38510 |
NNS |
denotes |
analyses |
T20081 |
38511-38513 |
IN |
denotes |
of |
T20082 |
38514-38519 |
NNP |
denotes |
PBMCs |
T20083 |
38520-38532 |
VBD |
denotes |
demonstrated |
T20084 |
38533-38534 |
DT |
denotes |
a |
T20085 |
38535-38549 |
JJ |
denotes |
time-dependent |
T20086 |
38550-38558 |
NN |
denotes |
decrease |
T20087 |
38559-38561 |
IN |
denotes |
in |
T20088 |
38562-38569 |
JJ |
denotes |
nuclear |
T20089 |
38570-38580 |
NN |
denotes |
expression |
T20090 |
38581-38583 |
IN |
denotes |
of |
T20091 |
38584-38590 |
NNP |
denotes |
GATA-3 |
T20092 |
38590-38591 |
, |
denotes |
, |
T20093 |
38592-38595 |
CC |
denotes |
and |
T20094 |
38596-38605 |
VBD |
denotes |
increased |
T20095 |
38606-38617 |
JJ |
denotes |
cytoplasmic |
T20096 |
38618-38624 |
JJ |
denotes |
GATA-3 |
T20097 |
38625-38635 |
NN |
denotes |
expression |
T20098 |
38636-38641 |
IN |
denotes |
after |
T20099 |
38642-38652 |
NN |
denotes |
inhalation |
T20100 |
38653-38655 |
IN |
denotes |
of |
T20101 |
38656-38658 |
NNP |
denotes |
FP |
T20102 |
38658-38659 |
. |
denotes |
. |
T20103 |
38660-38661 |
-LRB- |
denotes |
( |
T20104 |
38661-38662 |
NNP |
denotes |
D |
T20105 |
38662-38663 |
-RRB- |
denotes |
) |
T20106 |
38664-38678 |
NNP |
denotes |
Immunoblotting |
T20107 |
38679-38687 |
NNS |
denotes |
analyses |
T20108 |
38688-38690 |
IN |
denotes |
of |
T20109 |
38691-38696 |
NNP |
denotes |
PBMCs |
T20110 |
38697-38709 |
VBD |
denotes |
demonstrated |
T20111 |
38710-38711 |
DT |
denotes |
a |
T20112 |
38712-38726 |
JJ |
denotes |
dose-dependent |
T20113 |
38727-38735 |
NN |
denotes |
decrease |
T20114 |
38736-38738 |
IN |
denotes |
in |
T20115 |
38739-38746 |
JJ |
denotes |
nuclear |
T20116 |
38747-38757 |
NN |
denotes |
expression |
T20117 |
38758-38760 |
IN |
denotes |
of |
T20118 |
38761-38767 |
NNP |
denotes |
GATA-3 |
T20119 |
38767-38768 |
, |
denotes |
, |
T20120 |
38769-38772 |
CC |
denotes |
and |
T20121 |
38773-38782 |
VBD |
denotes |
increased |
T20122 |
38783-38794 |
JJ |
denotes |
cytoplasmic |
T20123 |
38795-38801 |
JJ |
denotes |
GATA-3 |
T20124 |
38802-38812 |
NN |
denotes |
expression |
T20125 |
38813-38814 |
CD |
denotes |
2 |
T20126 |
38815-38816 |
NN |
denotes |
h |
T20127 |
38817-38822 |
IN |
denotes |
after |
T20128 |
38823-38833 |
NN |
denotes |
inhalation |
T20129 |
38834-38836 |
IN |
denotes |
of |
T20130 |
38837-38839 |
NNP |
denotes |
FP |
T20131 |
38839-38840 |
. |
denotes |
. |
T20132 |
38841-38848 |
NNP |
denotes |
Histone |
T20133 |
38849-38851 |
NNP |
denotes |
H1 |
T20134 |
38852-38855 |
CC |
denotes |
and |
T20135 |
38856-38861 |
NNP |
denotes |
MEK-1 |
T20136 |
38862-38876 |
VBG |
denotes |
immunoblotting |
T20137 |
38877-38886 |
VBN |
denotes |
confirmed |
T20138 |
38887-38897 |
JJ |
denotes |
equivalent |
T20139 |
38898-38903 |
JJ |
denotes |
total |
T20140 |
38904-38911 |
NN |
denotes |
protein |
T20141 |
38912-38919 |
VBG |
denotes |
loading |
T20142 |
38920-38923 |
IN |
denotes |
for |
T20143 |
38924-38927 |
DT |
denotes |
the |
T20144 |
38928-38935 |
JJ |
denotes |
nuclear |
T20145 |
38936-38939 |
CC |
denotes |
and |
T20146 |
38940-38951 |
JJ |
denotes |
cytoplasmic |
T20147 |
38952-38961 |
NNS |
denotes |
fractions |
T20148 |
38962-38974 |
RB |
denotes |
respectively |
T20149 |
38974-38975 |
. |
denotes |
. |
T20150 |
38976-38990 |
NN |
denotes |
Quantification |
T20151 |
38991-38993 |
IN |
denotes |
of |
T20152 |
38994-38997 |
DT |
denotes |
the |
T20153 |
38998-39010 |
NN |
denotes |
densitometry |
T20154 |
39011-39015 |
NNS |
denotes |
data |
T20155 |
39016-39018 |
IN |
denotes |
in |
T20156 |
39019-39020 |
-LRB- |
denotes |
( |
T20157 |
39020-39021 |
NNP |
denotes |
C |
T20158 |
39021-39022 |
-RRB- |
denotes |
) |
T20159 |
39023-39026 |
CC |
denotes |
and |
T20160 |
39027-39028 |
-LRB- |
denotes |
( |
T20161 |
39028-39029 |
NNP |
denotes |
D |
T20162 |
39029-39030 |
-RRB- |
denotes |
) |
T20163 |
39031-39033 |
VBZ |
denotes |
is |
T20164 |
39034-39039 |
VBN |
denotes |
shown |
T20165 |
39040-39042 |
IN |
denotes |
as |
T20166 |
39043-39044 |
DT |
denotes |
a |
T20167 |
39045-39061 |
NNS |
denotes |
box-and-whiskers |
T20168 |
39062-39066 |
NN |
denotes |
plot |
T20169 |
39067-39069 |
IN |
denotes |
of |
T20170 |
39070-39077 |
NNS |
denotes |
results |
T20171 |
39078-39082 |
IN |
denotes |
from |
T20172 |
39083-39084 |
JJ |
denotes |
n |
T20173 |
39085-39086 |
SYM |
denotes |
= |
T20174 |
39087-39088 |
CD |
denotes |
6 |
T20175 |
39089-39101 |
NNS |
denotes |
participants |
T20176 |
39102-39105 |
IN |
denotes |
for |
T20177 |
39106-39111 |
WDT |
denotes |
which |
T20178 |
39112-39116 |
NNS |
denotes |
data |
T20179 |
39117-39121 |
VBD |
denotes |
were |
T20180 |
39122-39131 |
JJ |
denotes |
available |
T20181 |
39131-39132 |
. |
denotes |
. |
T20182 |
39133-39134 |
SYM |
denotes |
* |
T20183 |
39134-39135 |
NN |
denotes |
p |
T20184 |
39135-39136 |
NN |
denotes |
< |
T20185 |
39136-39140 |
CD |
denotes |
0.05 |
T20186 |
39141-39149 |
VBN |
denotes |
compared |
T20187 |
39150-39152 |
TO |
denotes |
to |
T20188 |
39153-39160 |
VB |
denotes |
control |
T20189 |
39160-39161 |
. |
denotes |
. |
T20190 |
39162-39163 |
-LRB- |
denotes |
( |
T20191 |
39163-39164 |
NNP |
denotes |
E |
T20192 |
39164-39165 |
-RRB- |
denotes |
) |
T20193 |
39166-39173 |
NNP |
denotes |
Western |
T20194 |
39174-39178 |
NN |
denotes |
blot |
T20195 |
39179-39187 |
NNS |
denotes |
analyses |
T20196 |
39188-39190 |
IN |
denotes |
of |
T20197 |
39191-39196 |
NNP |
denotes |
PBMCs |
T20198 |
39197-39209 |
VBD |
denotes |
demonstrated |
T20199 |
39210-39211 |
DT |
denotes |
a |
T20200 |
39212-39226 |
JJ |
denotes |
time-dependent |
T20201 |
39227-39235 |
NN |
denotes |
decrease |
T20202 |
39236-39238 |
IN |
denotes |
in |
T20203 |
39239-39243 |
JJ |
denotes |
dual |
T20204 |
39244-39259 |
NN |
denotes |
phosphorylation |
T20205 |
39260-39261 |
-LRB- |
denotes |
( |
T20206 |
39261-39274 |
NN |
denotes |
threonine-180 |
T20207 |
39275-39278 |
CC |
denotes |
and |
T20208 |
39279-39291 |
NN |
denotes |
tyrosine-182 |
T20209 |
39291-39292 |
-RRB- |
denotes |
) |
T20210 |
39293-39295 |
IN |
denotes |
of |
T20211 |
39296-39299 |
CD |
denotes |
p38 |
T20212 |
39300-39304 |
NNP |
denotes |
MAPK |
T20213 |
39305-39310 |
IN |
denotes |
after |
T20214 |
39311-39321 |
NN |
denotes |
inhalation |
T20215 |
39322-39324 |
IN |
denotes |
of |
T20216 |
39325-39327 |
NNP |
denotes |
FP |
T20217 |
39328-39329 |
-LRB- |
denotes |
( |
T20218 |
39329-39332 |
CD |
denotes |
500 |
T20219 |
39333-39335 |
NN |
denotes |
µg |
T20220 |
39335-39336 |
-RRB- |
denotes |
) |
T20221 |
39336-39337 |
. |
denotes |
. |
T20222 |
39338-39341 |
DT |
denotes |
The |
T20223 |
39342-39349 |
NNS |
denotes |
results |
T20224 |
39350-39355 |
VBN |
denotes |
shown |
T20225 |
39356-39358 |
IN |
denotes |
in |
T20226 |
39359-39360 |
-LRB- |
denotes |
( |
T20227 |
39360-39361 |
NNP |
denotes |
E |
T20228 |
39361-39362 |
-RRB- |
denotes |
) |
T20229 |
39363-39366 |
VBP |
denotes |
are |
T20230 |
39367-39381 |
NN |
denotes |
representative |
T20231 |
39382-39384 |
IN |
denotes |
of |
T20232 |
39385-39392 |
NNS |
denotes |
samples |
T20233 |
39393-39397 |
IN |
denotes |
from |
T20234 |
39398-39401 |
CD |
denotes |
two |
T20235 |
39402-39414 |
NNS |
denotes |
participants |
T20236 |
39414-39415 |
. |
denotes |
. |
T12480 |
39418-39423 |
VBN |
denotes |
Taken |
T12481 |
39424-39432 |
RB |
denotes |
together |
T12482 |
39432-39433 |
, |
denotes |
, |
T12483 |
39434-39437 |
PRP$ |
denotes |
our |
T12484 |
39438-39442 |
NNS |
denotes |
data |
T12485 |
39443-39450 |
VBP |
denotes |
suggest |
T12486 |
39451-39455 |
IN |
denotes |
that |
T12487 |
39456-39463 |
VBD |
denotes |
inhaled |
T12488 |
39464-39466 |
NNP |
denotes |
FP |
T12489 |
39467-39474 |
VBZ |
denotes |
reduces |
T12490 |
39475-39482 |
JJ |
denotes |
nuclear |
T12491 |
39483-39495 |
NN |
denotes |
localization |
T12492 |
39496-39498 |
IN |
denotes |
of |
T12493 |
39499-39505 |
NN |
denotes |
GATA-3 |
T12494 |
39506-39508 |
IN |
denotes |
in |
T12495 |
39509-39513 |
NN |
denotes |
vivo |
T12496 |
39514-39516 |
IN |
denotes |
by |
T12497 |
39517-39524 |
RB |
denotes |
acutely |
T12498 |
39525-39535 |
VBG |
denotes |
inhibiting |
T12499 |
39536-39550 |
JJ |
denotes |
phospho-GATA-3 |
T12500 |
39551-39559 |
NN |
denotes |
importin |
T12501 |
39560-39571 |
NN |
denotes |
association |
T12502 |
39571-39572 |
. |
denotes |
. |
T12503 |
39573-39577 |
DT |
denotes |
This |
T12504 |
39578-39584 |
NN |
denotes |
effect |
T12505 |
39585-39588 |
MD |
denotes |
may |
T12506 |
39589-39591 |
VB |
denotes |
be |
T12507 |
39592-39598 |
JJ |
denotes |
direct |
T12508 |
39598-39599 |
, |
denotes |
, |
T12509 |
39600-39607 |
IN |
denotes |
through |
T12510 |
39608-39619 |
NN |
denotes |
competition |
T12511 |
39620-39623 |
IN |
denotes |
for |
T12512 |
39624-39634 |
JJ |
denotes |
importin-α |
T12513 |
39635-39637 |
CC |
denotes |
or |
T12514 |
39638-39648 |
VBN |
denotes |
associated |
T12515 |
39649-39658 |
NNS |
denotes |
molecules |
T12516 |
39658-39659 |
, |
denotes |
, |
T12517 |
39660-39662 |
CC |
denotes |
or |
T12518 |
39663-39672 |
JJ |
denotes |
secondary |
T12519 |
39673-39675 |
TO |
denotes |
to |
T12520 |
39676-39678 |
DT |
denotes |
an |
T12521 |
39679-39685 |
NN |
denotes |
effect |
T12522 |
39686-39688 |
IN |
denotes |
on |
T12523 |
39689-39692 |
CD |
denotes |
p38 |
T12524 |
39693-39706 |
JJ |
denotes |
MAPK-mediated |
T12525 |
39707-39713 |
JJ |
denotes |
GATA-3 |
T12526 |
39714-39729 |
NN |
denotes |
phosphorylation |
T12527 |
39730-39733 |
IN |
denotes |
via |
T12528 |
39734-39739 |
JJ |
denotes |
rapid |
T12529 |
39740-39749 |
NN |
denotes |
induction |
T12530 |
39750-39752 |
IN |
denotes |
of |
T12531 |
39753-39758 |
NN |
denotes |
MKP-1 |
T12532 |
39758-39759 |
. |
denotes |
. |
T12533 |
39760-39763 |
DT |
denotes |
The |
T12534 |
39764-39775 |
NN |
denotes |
combination |
T12535 |
39776-39778 |
IN |
denotes |
of |
T12536 |
39779-39784 |
DT |
denotes |
these |
T12537 |
39785-39788 |
CD |
denotes |
two |
T12538 |
39789-39800 |
VBG |
denotes |
interacting |
T12539 |
39801-39808 |
NNS |
denotes |
effects |
T12540 |
39809-39812 |
MD |
denotes |
can |
T12541 |
39813-39819 |
VB |
denotes |
result |
T12542 |
39820-39822 |
IN |
denotes |
in |
T12543 |
39823-39831 |
JJ |
denotes |
complete |
T12544 |
39832-39843 |
NN |
denotes |
suppression |
T12545 |
39844-39846 |
IN |
denotes |
of |
T12546 |
39847-39853 |
JJ |
denotes |
GATA-3 |
T12547 |
39854-39861 |
JJ |
denotes |
nuclear |
T12548 |
39862-39868 |
NN |
denotes |
import |
T12549 |
39869-39872 |
CC |
denotes |
and |
T12550 |
39873-39877 |
RB |
denotes |
thus |
T12551 |
39878-39881 |
JJ |
denotes |
Th2 |
T12552 |
39882-39890 |
NN |
denotes |
cytokine |
T12553 |
39891-39895 |
NN |
denotes |
gene |
T12554 |
39896-39906 |
NN |
denotes |
expression |
T12555 |
39906-39907 |
. |
denotes |
. |
T14309 |
39920-39924 |
RB |
denotes |
Here |
T14310 |
39925-39927 |
PRP |
denotes |
we |
T14311 |
39928-39932 |
VBP |
denotes |
have |
T14312 |
39933-39945 |
VBN |
denotes |
demonstrated |
T14313 |
39945-39946 |
, |
denotes |
, |
T14314 |
39947-39949 |
TO |
denotes |
to |
T14315 |
39950-39953 |
PRP$ |
denotes |
our |
T14316 |
39954-39963 |
NN |
denotes |
knowledge |
T14317 |
39964-39967 |
IN |
denotes |
for |
T14318 |
39968-39971 |
DT |
denotes |
the |
T14319 |
39972-39977 |
JJ |
denotes |
first |
T14320 |
39978-39982 |
NN |
denotes |
time |
T14321 |
39982-39983 |
, |
denotes |
, |
T14322 |
39984-39988 |
IN |
denotes |
that |
T14323 |
39989-40004 |
NNS |
denotes |
corticosteroids |
T14324 |
40005-40008 |
MD |
denotes |
may |
T14325 |
40009-40016 |
VB |
denotes |
inhibit |
T14326 |
40017-40023 |
JJ |
denotes |
GATA-3 |
T14327 |
40024-40032 |
NN |
denotes |
function |
T14328 |
40033-40036 |
CC |
denotes |
and |
T14329 |
40037-40046 |
RB |
denotes |
therefore |
T14330 |
40047-40050 |
DT |
denotes |
the |
T14331 |
40051-40064 |
NN |
denotes |
transcription |
T14332 |
40065-40067 |
IN |
denotes |
of |
T14333 |
40068-40071 |
JJ |
denotes |
Th2 |
T14334 |
40072-40077 |
NNS |
denotes |
genes |
T14335 |
40078-40081 |
IN |
denotes |
via |
T14336 |
40082-40085 |
CD |
denotes |
two |
T14337 |
40086-40094 |
JJ |
denotes |
distinct |
T14338 |
40095-40098 |
CC |
denotes |
but |
T14339 |
40099-40110 |
VBG |
denotes |
interacting |
T14340 |
40111-40120 |
JJ |
denotes |
molecular |
T14341 |
40121-40131 |
NNS |
denotes |
mechanisms |
T14342 |
40131-40132 |
. |
denotes |
. |
T14343 |
40133-40140 |
RB |
denotes |
Firstly |
T14344 |
40140-40141 |
, |
denotes |
, |
T14345 |
40142-40166 |
JJ |
denotes |
corticosteroid-activated |
T14346 |
40167-40169 |
NNP |
denotes |
GR |
T14347 |
40170-40177 |
VBZ |
denotes |
appears |
T14348 |
40178-40180 |
TO |
denotes |
to |
T14349 |
40181-40188 |
VB |
denotes |
compete |
T14350 |
40189-40193 |
IN |
denotes |
with |
T14351 |
40194-40203 |
VBN |
denotes |
activated |
T14352 |
40204-40210 |
NNP |
denotes |
GATA-3 |
T14353 |
40211-40214 |
IN |
denotes |
for |
T14354 |
40215-40222 |
JJ |
denotes |
nuclear |
T14355 |
40223-40229 |
NN |
denotes |
import |
T14356 |
40230-40233 |
IN |
denotes |
via |
T14357 |
40234-40244 |
JJ |
denotes |
importin-α |
T14358 |
40244-40245 |
, |
denotes |
, |
T14359 |
40246-40251 |
WDT |
denotes |
which |
T14360 |
40252-40254 |
VBZ |
denotes |
is |
T14361 |
40255-40263 |
VBN |
denotes |
required |
T14362 |
40264-40267 |
IN |
denotes |
for |
T14363 |
40268-40271 |
DT |
denotes |
the |
T14364 |
40272-40279 |
JJ |
denotes |
nuclear |
T14365 |
40280-40289 |
NN |
denotes |
transport |
T14366 |
40290-40292 |
IN |
denotes |
of |
T14367 |
40293-40297 |
DT |
denotes |
both |
T14368 |
40298-40304 |
NNP |
denotes |
GATA-3 |
T14369 |
40305-40308 |
CC |
denotes |
and |
T14370 |
40309-40311 |
NNP |
denotes |
GR |
T14371 |
40311-40312 |
. |
denotes |
. |
T14372 |
40313-40321 |
RB |
denotes |
Secondly |
T14373 |
40321-40322 |
, |
denotes |
, |
T14374 |
40323-40338 |
NNS |
denotes |
corticosteroids |
T14375 |
40339-40341 |
IN |
denotes |
at |
T14376 |
40342-40348 |
JJR |
denotes |
higher |
T14377 |
40349-40363 |
NNS |
denotes |
concentrations |
T14378 |
40364-40372 |
VB |
denotes |
increase |
T14379 |
40373-40376 |
DT |
denotes |
the |
T14380 |
40377-40387 |
NN |
denotes |
expression |
T14381 |
40388-40390 |
IN |
denotes |
of |
T14382 |
40391-40396 |
NNP |
denotes |
MKP-1 |
T14383 |
40396-40397 |
, |
denotes |
, |
T14384 |
40398-40399 |
DT |
denotes |
a |
T14385 |
40400-40406 |
JJ |
denotes |
potent |
T14386 |
40407-40416 |
NN |
denotes |
inhibitor |
T14387 |
40417-40419 |
IN |
denotes |
of |
T14388 |
40420-40423 |
CD |
denotes |
p38 |
T14389 |
40424-40428 |
NNP |
denotes |
MAPK |
T14390 |
40429-40437 |
NN |
denotes |
activity |
T14391 |
40438-40441 |
CC |
denotes |
and |
T14392 |
40442-40449 |
RB |
denotes |
thereby |
T14393 |
40450-40457 |
VB |
denotes |
prevent |
T14394 |
40458-40459 |
NNP |
denotes |
T |
T14395 |
40460-40464 |
NN |
denotes |
cell |
T14396 |
40465-40485 |
NN |
denotes |
receptor/co-receptor |
T14397 |
40486-40496 |
NN |
denotes |
activation |
T14398 |
40497-40499 |
IN |
denotes |
of |
T14399 |
40500-40503 |
CD |
denotes |
p38 |
T14400 |
40504-40508 |
NNP |
denotes |
MAPK |
T14401 |
40509-40511 |
TO |
denotes |
to |
T14402 |
40512-40519 |
VB |
denotes |
prevent |
T14403 |
40520-40523 |
DT |
denotes |
the |
T14404 |
40524-40539 |
NN |
denotes |
phosphorylation |
T14405 |
40540-40542 |
IN |
denotes |
of |
T14406 |
40543-40549 |
NN |
denotes |
GATA-3 |
T14407 |
40550-40554 |
WDT |
denotes |
that |
T14408 |
40555-40557 |
VBZ |
denotes |
is |
T14409 |
40558-40567 |
JJ |
denotes |
necessary |
T14410 |
40568-40571 |
IN |
denotes |
for |
T14411 |
40572-40583 |
NN |
denotes |
interaction |
T14412 |
40584-40588 |
IN |
denotes |
with |
T14413 |
40589-40599 |
JJ |
denotes |
importin-α |
T14414 |
40600-40603 |
CC |
denotes |
and |
T14415 |
40604-40614 |
JJ |
denotes |
subsequent |
T14416 |
40615-40622 |
JJ |
denotes |
nuclear |
T14417 |
40623-40629 |
NN |
denotes |
import |
T14418 |
40629-40630 |
. |
denotes |
. |
T14419 |
40631-40633 |
PRP |
denotes |
We |
T14420 |
40634-40638 |
VBP |
denotes |
have |
T14421 |
40639-40649 |
RB |
denotes |
previously |
T14422 |
40650-40655 |
VBN |
denotes |
shown |
T14423 |
40656-40660 |
IN |
denotes |
that |
T14424 |
40661-40674 |
NN |
denotes |
translocation |
T14425 |
40675-40677 |
IN |
denotes |
of |
T14426 |
40678-40684 |
NN |
denotes |
GATA-3 |
T14427 |
40685-40689 |
IN |
denotes |
from |
T14428 |
40690-40693 |
DT |
denotes |
the |
T14429 |
40694-40703 |
NN |
denotes |
cytoplasm |
T14430 |
40704-40706 |
TO |
denotes |
to |
T14431 |
40707-40710 |
DT |
denotes |
the |
T14432 |
40711-40718 |
NN |
denotes |
nucleus |
T14433 |
40719-40727 |
VBZ |
denotes |
involves |
T14434 |
40728-40731 |
DT |
denotes |
the |
T14435 |
40732-40739 |
JJ |
denotes |
nuclear |
T14436 |
40740-40751 |
NN |
denotes |
transporter |
T14437 |
40752-40759 |
NN |
denotes |
protein |
T14438 |
40760-40770 |
NN |
denotes |
importin-α |
T14439 |
40770-40771 |
, |
denotes |
, |
T14440 |
40772-40777 |
WDT |
denotes |
which |
T14441 |
40778-40787 |
VBZ |
denotes |
interacts |
T14442 |
40788-40792 |
IN |
denotes |
with |
T14443 |
40793-40807 |
VBN |
denotes |
phosphorylated |
T14444 |
40808-40814 |
NNP |
denotes |
GATA-3 |
T14445 |
40815-40816 |
NNP |
denotes |
[ |
T14446 |
40816-40818 |
CD |
denotes |
12 |
T14447 |
40818-40819 |
NNP |
denotes |
] |
T14448 |
40819-40820 |
. |
denotes |
. |
T14449 |
40821-40823 |
PRP |
denotes |
We |
T14450 |
40824-40828 |
VBP |
denotes |
have |
T14451 |
40829-40833 |
RB |
denotes |
also |
T14452 |
40834-40844 |
RB |
denotes |
previously |
T14453 |
40845-40853 |
VBN |
denotes |
reported |
T14454 |
40854-40858 |
IN |
denotes |
that |
T14455 |
40859-40865 |
JJ |
denotes |
GATA-3 |
T14456 |
40866-40875 |
NN |
denotes |
knockdown |
T14457 |
40876-40881 |
VBG |
denotes |
using |
T14458 |
40882-40887 |
NNP |
denotes |
siRNA |
T14459 |
40888-40895 |
NNS |
denotes |
results |
T14460 |
40896-40898 |
IN |
denotes |
in |
T14461 |
40899-40910 |
NN |
denotes |
suppression |
T14462 |
40911-40913 |
IN |
denotes |
of |
T14463 |
40914-40922 |
JJ |
denotes |
anti-CD3 |
T14464 |
40922-40923 |
NN |
denotes |
/ |
T14465 |
40923-40927 |
CD |
denotes |
CD28 |
T14466 |
40928-40938 |
VBD |
denotes |
stimulated |
T14467 |
40939-40943 |
NN |
denotes |
IL-4 |
T14468 |
40943-40944 |
NN |
denotes |
/ |
T14469 |
40944-40948 |
NN |
denotes |
IL-5 |
T14470 |
40949-40953 |
NNP |
denotes |
mRNA |
T14471 |
40954-40963 |
NN |
denotes |
induction |
T14472 |
40963-40964 |
, |
denotes |
, |
T14473 |
40965-40969 |
RB |
denotes |
thus |
T14474 |
40970-40981 |
VBG |
denotes |
implicating |
T14475 |
40982-40984 |
DT |
denotes |
an |
T14476 |
40985-40994 |
JJ |
denotes |
essential |
T14477 |
40995-40999 |
NN |
denotes |
role |
T14478 |
41000-41003 |
IN |
denotes |
for |
T14479 |
41004-41010 |
NNP |
denotes |
GATA-3 |
T14480 |
41011-41013 |
IN |
denotes |
in |
T14481 |
41014-41017 |
DT |
denotes |
the |
T14482 |
41018-41031 |
NN |
denotes |
transcription |
T14483 |
41032-41034 |
IN |
denotes |
of |
T14484 |
41035-41040 |
DT |
denotes |
these |
T14485 |
41041-41046 |
NNS |
denotes |
genes |
T14486 |
41047-41048 |
NNP |
denotes |
[ |
T14487 |
41048-41050 |
CD |
denotes |
12 |
T14488 |
41050-41051 |
NNP |
denotes |
] |
T14489 |
41051-41052 |
. |
denotes |
. |
T14490 |
41053-41055 |
PRP |
denotes |
We |
T14491 |
41056-41059 |
RB |
denotes |
now |
T14492 |
41060-41067 |
VBP |
denotes |
confirm |
T14493 |
41067-41068 |
, |
denotes |
, |
T14494 |
41069-41071 |
IN |
denotes |
in |
T14495 |
41072-41077 |
JJ |
denotes |
human |
T14496 |
41078-41079 |
NNP |
denotes |
T |
T14497 |
41080-41085 |
NNS |
denotes |
cells |
T14498 |
41085-41086 |
, |
denotes |
, |
T14499 |
41087-41091 |
IN |
denotes |
that |
T14500 |
41092-41094 |
NNP |
denotes |
GR |
T14501 |
41095-41099 |
RB |
denotes |
also |
T14502 |
41100-41104 |
VBZ |
denotes |
uses |
T14503 |
41105-41108 |
DT |
denotes |
the |
T14504 |
41109-41113 |
JJ |
denotes |
same |
T14505 |
41114-41121 |
JJ |
denotes |
nuclear |
T14506 |
41122-41128 |
NN |
denotes |
import |
T14507 |
41129-41138 |
NN |
denotes |
mechanism |
T14508 |
41139-41141 |
IN |
denotes |
as |
T14509 |
41142-41148 |
JJ |
denotes |
GATA-3 |
T14510 |
41149-41150 |
NNP |
denotes |
[ |
T14511 |
41150-41152 |
CD |
denotes |
22 |
T14512 |
41152-41153 |
NNP |
denotes |
] |
T14513 |
41153-41154 |
. |
denotes |
. |
T14514 |
41155-41157 |
PRP |
denotes |
We |
T14515 |
41158-41167 |
RB |
denotes |
therefore |
T14516 |
41168-41175 |
VBP |
denotes |
propose |
T14517 |
41176-41180 |
IN |
denotes |
that |
T14518 |
41181-41186 |
EX |
denotes |
there |
T14519 |
41187-41189 |
VBZ |
denotes |
is |
T14520 |
41190-41201 |
NN |
denotes |
competition |
T14521 |
41202-41209 |
IN |
denotes |
between |
T14522 |
41210-41226 |
JJ |
denotes |
ligand-activated |
T14523 |
41227-41229 |
NNP |
denotes |
GR |
T14524 |
41230-41233 |
CC |
denotes |
and |
T14525 |
41234-41248 |
NNP |
denotes |
phospho-GATA-3 |
T14526 |
41249-41252 |
IN |
denotes |
for |
T14527 |
41253-41260 |
JJ |
denotes |
nuclear |
T14528 |
41261-41267 |
NN |
denotes |
import |
T14529 |
41267-41268 |
. |
denotes |
. |
T14530 |
41269-41280 |
RB |
denotes |
Furthermore |
T14531 |
41280-41281 |
, |
denotes |
, |
T14532 |
41282-41284 |
PRP |
denotes |
we |
T14533 |
41285-41289 |
VBP |
denotes |
have |
T14534 |
41290-41295 |
VBN |
denotes |
shown |
T14535 |
41296-41300 |
IN |
denotes |
that |
T14536 |
41301-41306 |
EX |
denotes |
there |
T14537 |
41307-41309 |
VBZ |
denotes |
is |
T14538 |
41310-41322 |
JJ |
denotes |
preferential |
T14539 |
41323-41330 |
JJ |
denotes |
binding |
T14540 |
41331-41333 |
IN |
denotes |
of |
T14541 |
41334-41344 |
JJ |
denotes |
importin-α |
T14542 |
41345-41347 |
TO |
denotes |
to |
T14543 |
41348-41357 |
VBN |
denotes |
activated |
T14544 |
41358-41360 |
NNP |
denotes |
GR |
T14545 |
41361-41365 |
IN |
denotes |
over |
T14546 |
41366-41380 |
NNP |
denotes |
phospho-GATA-3 |
T14547 |
41380-41381 |
, |
denotes |
, |
T14548 |
41382-41384 |
RB |
denotes |
so |
T14549 |
41385-41389 |
IN |
denotes |
that |
T14550 |
41390-41405 |
NNS |
denotes |
corticosteroids |
T14551 |
41406-41411 |
MD |
denotes |
would |
T14552 |
41412-41426 |
RB |
denotes |
preferentially |
T14553 |
41427-41433 |
VB |
denotes |
reduce |
T14554 |
41434-41440 |
JJ |
denotes |
GATA-3 |
T14555 |
41441-41446 |
NN |
denotes |
entry |
T14556 |
41447-41450 |
CC |
denotes |
and |
T14557 |
41451-41455 |
RB |
denotes |
thus |
T14558 |
41456-41463 |
RB |
denotes |
rapidly |
T14559 |
41464-41470 |
VB |
denotes |
switch |
T14560 |
41471-41474 |
RP |
denotes |
off |
T14561 |
41475-41478 |
CD |
denotes |
Th2 |
T14562 |
41479-41483 |
NN |
denotes |
gene |
T14563 |
41484-41497 |
NN |
denotes |
transcription |
T14564 |
41498-41505 |
IN |
denotes |
without |
T14565 |
41506-41509 |
DT |
denotes |
any |
T14566 |
41510-41514 |
NN |
denotes |
need |
T14567 |
41515-41518 |
IN |
denotes |
for |
T14568 |
41519-41522 |
DT |
denotes |
any |
T14569 |
41523-41535 |
JJ |
denotes |
intermediate |
T14570 |
41536-41541 |
NNS |
denotes |
steps |
T14571 |
41541-41542 |
. |
denotes |
. |
T14572 |
41543-41554 |
RB |
denotes |
Furthermore |
T14573 |
41554-41555 |
, |
denotes |
, |
T14574 |
41556-41561 |
EX |
denotes |
there |
T14575 |
41562-41565 |
VBD |
denotes |
was |
T14576 |
41566-41570 |
DT |
denotes |
some |
T14577 |
41571-41577 |
NN |
denotes |
degree |
T14578 |
41578-41580 |
IN |
denotes |
of |
T14579 |
41581-41592 |
NN |
denotes |
specificity |
T14580 |
41593-41596 |
IN |
denotes |
for |
T14581 |
41597-41603 |
NNP |
denotes |
GATA-3 |
T14582 |
41603-41604 |
, |
denotes |
, |
T14583 |
41605-41607 |
IN |
denotes |
as |
T14584 |
41608-41615 |
JJ |
denotes |
nuclear |
T14585 |
41616-41629 |
NN |
denotes |
translocation |
T14586 |
41630-41632 |
IN |
denotes |
of |
T14587 |
41633-41636 |
DT |
denotes |
the |
T14588 |
41637-41640 |
CD |
denotes |
p65 |
T14589 |
41641-41648 |
NN |
denotes |
subunit |
T14590 |
41649-41651 |
IN |
denotes |
of |
T14591 |
41652-41657 |
NN |
denotes |
NF-κB |
T14592 |
41658-41661 |
VBD |
denotes |
was |
T14593 |
41662-41665 |
RB |
denotes |
not |
T14594 |
41666-41674 |
VBN |
denotes |
affected |
T14595 |
41675-41677 |
IN |
denotes |
by |
T14596 |
41678-41692 |
JJ |
denotes |
corticosteroid |
T14597 |
41693-41701 |
NN |
denotes |
exposure |
T14598 |
41701-41702 |
. |
denotes |
. |
T14599 |
41703-41705 |
PRP |
denotes |
We |
T14600 |
41706-41712 |
VBD |
denotes |
tested |
T14601 |
41713-41717 |
DT |
denotes |
some |
T14602 |
41718-41729 |
JJ |
denotes |
alternative |
T14603 |
41730-41742 |
NNS |
denotes |
explanations |
T14604 |
41743-41746 |
IN |
denotes |
for |
T14605 |
41747-41751 |
DT |
denotes |
this |
T14606 |
41752-41758 |
NN |
denotes |
effect |
T14607 |
41759-41761 |
IN |
denotes |
of |
T14608 |
41762-41764 |
NNP |
denotes |
FP |
T14609 |
41765-41767 |
IN |
denotes |
on |
T14610 |
41768-41774 |
NNP |
denotes |
GATA-3 |
T14611 |
41775-41782 |
JJ |
denotes |
nuclear |
T14612 |
41783-41792 |
NN |
denotes |
exclusion |
T14613 |
41793-41796 |
CC |
denotes |
and |
T14614 |
41797-41803 |
VBD |
denotes |
failed |
T14615 |
41804-41806 |
TO |
denotes |
to |
T14616 |
41807-41811 |
VB |
denotes |
show |
T14617 |
41812-41816 |
IN |
denotes |
that |
T14618 |
41817-41819 |
NNP |
denotes |
FP |
T14619 |
41820-41826 |
CC |
denotes |
either |
T14620 |
41827-41835 |
VBZ |
denotes |
enhances |
T14621 |
41836-41842 |
JJ |
denotes |
GATA-3 |
T14622 |
41843-41850 |
JJ |
denotes |
nuclear |
T14623 |
41851-41857 |
NN |
denotes |
export |
T14624 |
41858-41866 |
RB |
denotes |
directly |
T14625 |
41867-41869 |
CC |
denotes |
or |
T14626 |
41870-41877 |
VBZ |
denotes |
induces |
T14627 |
41878-41884 |
JJ |
denotes |
GATA-3 |
T14628 |
41885-41896 |
NN |
denotes |
degradation |
T14629 |
41896-41897 |
. |
denotes |
. |
T14630 |
41898-41901 |
DT |
denotes |
The |
T14631 |
41902-41910 |
NN |
denotes |
evidence |
T14632 |
41911-41915 |
IN |
denotes |
from |
T14633 |
41916-41919 |
DT |
denotes |
the |
T14634 |
41920-41922 |
IN |
denotes |
in |
T14635 |
41923-41928 |
NN |
denotes |
vitro |
T14636 |
41929-41940 |
NN |
denotes |
competition |
T14637 |
41941-41947 |
VBZ |
denotes |
assays |
T14638 |
41948-41952 |
VBZ |
denotes |
does |
T14639 |
41952-41953 |
, |
denotes |
, |
T14640 |
41954-41961 |
RB |
denotes |
however |
T14641 |
41961-41962 |
, |
denotes |
, |
T14642 |
41963-41970 |
VBP |
denotes |
suggest |
T14643 |
41971-41975 |
IN |
denotes |
that |
T14644 |
41976-41984 |
JJ |
denotes |
purified |
T14645 |
41985-41994 |
VBN |
denotes |
activated |
T14646 |
41995-41997 |
NNP |
denotes |
GR |
T14647 |
41998-42001 |
MD |
denotes |
can |
T14648 |
42002-42009 |
RB |
denotes |
clearly |
T14649 |
42010-42019 |
VB |
denotes |
attenuate |
T14650 |
42020-42028 |
VBN |
denotes |
purified |
T14651 |
42029-42043 |
JJ |
denotes |
phospho-GATA-3 |
T14652 |
42044-42054 |
JJ |
denotes |
importin-α |
T14653 |
42055-42066 |
NN |
denotes |
association |
T14654 |
42067-42070 |
CC |
denotes |
and |
T14655 |
42071-42075 |
IN |
denotes |
that |
T14656 |
42076-42079 |
DT |
denotes |
the |
T14657 |
42080-42088 |
NN |
denotes |
converse |
T14658 |
42089-42093 |
VBZ |
denotes |
does |
T14659 |
42094-42097 |
RB |
denotes |
not |
T14660 |
42098-42103 |
VB |
denotes |
occur |
T14661 |
42103-42104 |
. |
denotes |
. |
T14662 |
42105-42116 |
RB |
denotes |
Furthermore |
T14663 |
42116-42117 |
, |
denotes |
, |
T14664 |
42118-42120 |
PRP |
denotes |
we |
T14665 |
42121-42125 |
VBP |
denotes |
have |
T14666 |
42126-42131 |
VBN |
denotes |
shown |
T14667 |
42132-42136 |
IN |
denotes |
that |
T14668 |
42137-42141 |
RB |
denotes |
only |
T14669 |
42142-42156 |
JJ |
denotes |
phospho-GATA-3 |
T14670 |
42157-42160 |
MD |
denotes |
can |
T14671 |
42161-42170 |
VB |
denotes |
associate |
T14672 |
42171-42175 |
IN |
denotes |
with |
T14673 |
42176-42186 |
JJ |
denotes |
importin-α |
T14674 |
42186-42187 |
. |
denotes |
. |
T14675 |
42188-42192 |
DT |
denotes |
This |
T14676 |
42193-42202 |
NN |
denotes |
mechanism |
T14677 |
42203-42205 |
VBZ |
denotes |
is |
T14678 |
42206-42215 |
JJ |
denotes |
sensitive |
T14679 |
42216-42218 |
TO |
denotes |
to |
T14680 |
42219-42223 |
RB |
denotes |
very |
T14681 |
42224-42227 |
JJ |
denotes |
low |
T14682 |
42228-42242 |
NNS |
denotes |
concentrations |
T14683 |
42243-42245 |
IN |
denotes |
of |
T14684 |
42246-42260 |
JJ |
denotes |
corticosteroid |
T14685 |
42261-42264 |
CC |
denotes |
and |
T14686 |
42265-42270 |
MD |
denotes |
would |
T14687 |
42271-42273 |
VB |
denotes |
be |
T14688 |
42274-42279 |
JJ |
denotes |
rapid |
T14689 |
42280-42282 |
IN |
denotes |
in |
T14690 |
42283-42288 |
NN |
denotes |
onset |
T14691 |
42289-42291 |
IN |
denotes |
as |
T14692 |
42292-42294 |
DT |
denotes |
no |
T14693 |
42295-42302 |
NNS |
denotes |
changes |
T14694 |
42303-42305 |
IN |
denotes |
in |
T14695 |
42306-42313 |
NN |
denotes |
protein |
T14696 |
42314-42323 |
NN |
denotes |
synthesis |
T14697 |
42324-42327 |
VBP |
denotes |
are |
T14698 |
42328-42336 |
VBN |
denotes |
required |
T14699 |
42336-42337 |
. |
denotes |
. |
T14700 |
42338-42342 |
DT |
denotes |
This |
T14701 |
42343-42348 |
JJ |
denotes |
acute |
T14702 |
42349-42358 |
NN |
denotes |
mechanism |
T14703 |
42359-42362 |
MD |
denotes |
may |
T14704 |
42363-42367 |
RB |
denotes |
also |
T14705 |
42368-42378 |
VB |
denotes |
contribute |
T14706 |
42379-42381 |
TO |
denotes |
to |
T14707 |
42382-42385 |
DT |
denotes |
the |
T14708 |
42386-42395 |
NN |
denotes |
reduction |
T14709 |
42396-42398 |
IN |
denotes |
in |
T14710 |
42399-42405 |
JJ |
denotes |
GATA-3 |
T14711 |
42406-42413 |
JJ |
denotes |
nuclear |
T14712 |
42414-42420 |
NN |
denotes |
import |
T14713 |
42421-42424 |
CC |
denotes |
and |
T14714 |
42425-42428 |
MD |
denotes |
may |
T14715 |
42429-42433 |
VB |
denotes |
play |
T14716 |
42434-42435 |
DT |
denotes |
a |
T14717 |
42436-42441 |
JJ |
denotes |
major |
T14718 |
42442-42446 |
NN |
denotes |
role |
T14719 |
42447-42449 |
IN |
denotes |
at |
T14720 |
42450-42453 |
JJ |
denotes |
low |
T14721 |
42454-42468 |
JJ |
denotes |
corticosteroid |
T14722 |
42469-42483 |
NNS |
denotes |
concentrations |
T14723 |
42484-42490 |
CC |
denotes |
and/or |
T14724 |
42491-42493 |
IN |
denotes |
at |
T14725 |
42494-42499 |
JJ |
denotes |
early |
T14726 |
42500-42504 |
NN |
denotes |
time |
T14727 |
42505-42511 |
NNS |
denotes |
points |
T14728 |
42512-42517 |
RB |
denotes |
prior |
T14729 |
42518-42520 |
TO |
denotes |
to |
T14730 |
42521-42526 |
NNP |
denotes |
MKP-1 |
T14731 |
42527-42536 |
NN |
denotes |
induction |
T14732 |
42536-42537 |
. |
denotes |
. |
T14733 |
42538-42553 |
NNS |
denotes |
Corticosteroids |
T14734 |
42554-42557 |
MD |
denotes |
can |
T14735 |
42558-42566 |
VB |
denotes |
modulate |
T14736 |
42567-42570 |
CD |
denotes |
p38 |
T14737 |
42571-42575 |
NNP |
denotes |
MAPK |
T14738 |
42576-42584 |
NN |
denotes |
activity |
T14739 |
42585-42592 |
IN |
denotes |
through |
T14740 |
42593-42596 |
DT |
denotes |
the |
T14741 |
42597-42606 |
NN |
denotes |
induction |
T14742 |
42607-42609 |
IN |
denotes |
of |
T14743 |
42610-42615 |
NNP |
denotes |
MKP-1 |
T14744 |
42615-42616 |
, |
denotes |
, |
T14745 |
42617-42618 |
DT |
denotes |
a |
T14746 |
42619-42625 |
JJ |
denotes |
potent |
T14747 |
42626-42636 |
JJ |
denotes |
endogenous |
T14748 |
42637-42646 |
NN |
denotes |
inhibitor |
T14749 |
42647-42649 |
IN |
denotes |
of |
T14750 |
42650-42654 |
NNP |
denotes |
MAPK |
T14751 |
42655-42663 |
NN |
denotes |
function |
T14752 |
42664-42665 |
NNP |
denotes |
[ |
T14753 |
42665-42667 |
CD |
denotes |
38 |
T14754 |
42667-42668 |
NNP |
denotes |
] |
T14755 |
42668-42669 |
, |
denotes |
, |
T14756 |
42669-42670 |
NNP |
denotes |
[ |
T14757 |
42670-42672 |
CD |
denotes |
39 |
T14758 |
42672-42673 |
NNP |
denotes |
] |
T14759 |
42673-42674 |
. |
denotes |
. |
T14760 |
42675-42677 |
PRP |
denotes |
We |
T14761 |
42678-42684 |
VBP |
denotes |
report |
T14762 |
42685-42689 |
RB |
denotes |
here |
T14763 |
42690-42691 |
DT |
denotes |
a |
T14764 |
42692-42697 |
JJ |
denotes |
rapid |
T14765 |
42698-42707 |
NN |
denotes |
induction |
T14766 |
42708-42710 |
IN |
denotes |
of |
T14767 |
42711-42716 |
NNP |
denotes |
MKP-1 |
T14768 |
42717-42721 |
NNP |
denotes |
mRNA |
T14769 |
42722-42731 |
VBG |
denotes |
following |
T14770 |
42732-42743 |
NN |
denotes |
stimulation |
T14771 |
42744-42746 |
IN |
denotes |
of |
T14772 |
42747-42752 |
NNS |
denotes |
cells |
T14773 |
42753-42757 |
IN |
denotes |
with |
T14774 |
42758-42768 |
RB |
denotes |
relatively |
T14775 |
42769-42773 |
JJ |
denotes |
high |
T14776 |
42774-42788 |
NNS |
denotes |
concentrations |
T14777 |
42789-42791 |
IN |
denotes |
of |
T14778 |
42792-42794 |
NNP |
denotes |
FP |
T14779 |
42794-42795 |
. |
denotes |
. |
T14780 |
42796-42798 |
PRP |
denotes |
We |
T14781 |
42799-42810 |
VBP |
denotes |
hypothesize |
T14782 |
42811-42815 |
IN |
denotes |
that |
T14783 |
42816-42820 |
DT |
denotes |
this |
T14784 |
42821-42826 |
JJ |
denotes |
rapid |
T14785 |
42827-42836 |
NN |
denotes |
induction |
T14786 |
42837-42839 |
IN |
denotes |
of |
T14787 |
42840-42845 |
NN |
denotes |
MKP-1 |
T14788 |
42846-42849 |
MD |
denotes |
can |
T14789 |
42850-42856 |
VB |
denotes |
reduce |
T14790 |
42857-42863 |
JJ |
denotes |
GATA-3 |
T14791 |
42864-42871 |
JJ |
denotes |
nuclear |
T14792 |
42872-42878 |
NN |
denotes |
import |
T14793 |
42879-42881 |
IN |
denotes |
by |
T14794 |
42882-42893 |
VBG |
denotes |
attenuating |
T14795 |
42894-42897 |
CD |
denotes |
p38 |
T14796 |
42898-42902 |
NNP |
denotes |
MAPK |
T14797 |
42903-42911 |
NN |
denotes |
activity |
T14798 |
42912-42915 |
CC |
denotes |
and |
T14799 |
42916-42926 |
JJ |
denotes |
subsequent |
T14800 |
42927-42933 |
NN |
denotes |
GATA-3 |
T14801 |
42934-42949 |
NN |
denotes |
phosphorylation |
T14802 |
42949-42950 |
, |
denotes |
, |
T14803 |
42951-42955 |
RB |
denotes |
thus |
T14804 |
42956-42966 |
VBG |
denotes |
preventing |
T14805 |
42967-42974 |
JJ |
denotes |
nuclear |
T14806 |
42975-42988 |
NN |
denotes |
translocation |
T14807 |
42988-42989 |
. |
denotes |
. |
T14808 |
42990-42993 |
DT |
denotes |
The |
T14809 |
42994-43002 |
NN |
denotes |
location |
T14810 |
43003-43005 |
IN |
denotes |
of |
T14811 |
43006-43009 |
DT |
denotes |
the |
T14812 |
43010-43016 |
NN |
denotes |
serine |
T14813 |
43017-43024 |
NN |
denotes |
residue |
T14814 |
43024-43025 |
-LRB- |
denotes |
( |
T14815 |
43025-43026 |
PRP |
denotes |
s |
T14816 |
43026-43027 |
-RRB- |
denotes |
) |
T14817 |
43028-43030 |
IN |
denotes |
of |
T14818 |
43031-43037 |
NN |
denotes |
GATA-3 |
T14819 |
43038-43042 |
WDT |
denotes |
that |
T14820 |
43043-43046 |
VBP |
denotes |
are |
T14821 |
43047-43061 |
VBN |
denotes |
phosphorylated |
T14822 |
43062-43064 |
IN |
denotes |
by |
T14823 |
43065-43068 |
CD |
denotes |
p38 |
T14824 |
43069-43073 |
NNP |
denotes |
MAPK |
T14825 |
43074-43077 |
VBP |
denotes |
are |
T14826 |
43078-43087 |
RB |
denotes |
currently |
T14827 |
43088-43095 |
JJ |
denotes |
unknown |
T14828 |
43095-43096 |
, |
denotes |
, |
T14829 |
43097-43100 |
CC |
denotes |
but |
T14830 |
43101-43102 |
DT |
denotes |
a |
T14831 |
43103-43117 |
NNS |
denotes |
bioinformatics |
T14832 |
43118-43124 |
NN |
denotes |
search |
T14833 |
43125-43126 |
-LRB- |
denotes |
( |
T14834 |
43126-43131 |
NNP |
denotes |
Motif |
T14835 |
43132-43139 |
NNP |
denotes |
Scanner |
T14836 |
43139-43140 |
, |
denotes |
, |
T14837 |
43141-43184 |
NNP |
denotes |
http://scansite.mit.edu/motifscan_seq.phtml |
T14838 |
43184-43185 |
-RRB- |
denotes |
) |
T14839 |
43186-43195 |
VBZ |
denotes |
indicates |
T14840 |
43196-43198 |
IN |
denotes |
at |
T14841 |
43199-43204 |
JJS |
denotes |
least |
T14842 |
43205-43210 |
CD |
denotes |
three |
T14843 |
43211-43220 |
JJ |
denotes |
potential |
T14844 |
43221-43224 |
CD |
denotes |
p38 |
T14845 |
43225-43239 |
JJ |
denotes |
MAPK-sensitive |
T14846 |
43240-43246 |
NN |
denotes |
serine |
T14847 |
43247-43255 |
NNS |
denotes |
residues |
T14848 |
43255-43256 |
. |
denotes |
. |
T14849 |
43257-43259 |
IN |
denotes |
As |
T14850 |
43260-43269 |
VBN |
denotes |
predicted |
T14851 |
43270-43274 |
IN |
denotes |
from |
T14852 |
43275-43280 |
DT |
denotes |
these |
T14853 |
43281-43283 |
IN |
denotes |
in |
T14854 |
43284-43289 |
NN |
denotes |
vitro |
T14855 |
43290-43294 |
NNS |
denotes |
data |
T14856 |
43294-43295 |
, |
denotes |
, |
T14857 |
43296-43306 |
NN |
denotes |
impairment |
T14858 |
43307-43309 |
IN |
denotes |
of |
T14859 |
43310-43316 |
JJ |
denotes |
GATA-3 |
T14860 |
43317-43324 |
JJ |
denotes |
nuclear |
T14861 |
43325-43331 |
NN |
denotes |
import |
T14862 |
43332-43334 |
IN |
denotes |
by |
T14863 |
43335-43337 |
NNP |
denotes |
FP |
T14864 |
43338-43341 |
MD |
denotes |
may |
T14865 |
43341-43342 |
, |
denotes |
, |
T14866 |
43343-43345 |
IN |
denotes |
at |
T14867 |
43346-43351 |
JJS |
denotes |
least |
T14868 |
43352-43354 |
IN |
denotes |
in |
T14869 |
43355-43359 |
NN |
denotes |
part |
T14870 |
43359-43360 |
, |
denotes |
, |
T14871 |
43361-43369 |
VBP |
denotes |
underlie |
T14872 |
43370-43373 |
DT |
denotes |
the |
T14873 |
43374-43382 |
NN |
denotes |
efficacy |
T14874 |
43383-43385 |
IN |
denotes |
of |
T14875 |
43386-43401 |
NNS |
denotes |
corticosteroids |
T14876 |
43402-43404 |
IN |
denotes |
in |
T14877 |
43405-43416 |
VBG |
denotes |
suppressing |
T14878 |
43417-43425 |
JJ |
denotes |
allergic |
T14879 |
43426-43438 |
NN |
denotes |
inflammation |
T14880 |
43438-43439 |
. |
denotes |
. |
T14881 |
43440-43448 |
IN |
denotes |
Although |
T14882 |
43449-43451 |
PRP |
denotes |
we |
T14883 |
43452-43455 |
VBD |
denotes |
did |
T14884 |
43456-43459 |
RB |
denotes |
not |
T14885 |
43460-43466 |
VB |
denotes |
assess |
T14886 |
43467-43470 |
DT |
denotes |
the |
T14887 |
43471-43476 |
JJ |
denotes |
acute |
T14888 |
43477-43487 |
JJ |
denotes |
inhibitory |
T14889 |
43488-43494 |
NN |
denotes |
effect |
T14890 |
43495-43497 |
IN |
denotes |
of |
T14891 |
43498-43500 |
NNP |
denotes |
FP |
T14892 |
43501-43503 |
IN |
denotes |
on |
T14893 |
43504-43507 |
DT |
denotes |
the |
T14894 |
43508-43518 |
NN |
denotes |
expression |
T14895 |
43519-43521 |
IN |
denotes |
of |
T14896 |
43522-43526 |
NN |
denotes |
IL-4 |
T14897 |
43527-43531 |
NNP |
denotes |
mRNA |
T14898 |
43532-43534 |
IN |
denotes |
in |
T14899 |
43535-43539 |
NN |
denotes |
vivo |
T14900 |
43539-43540 |
, |
denotes |
, |
T14901 |
43541-43542 |
DT |
denotes |
a |
T14902 |
43543-43549 |
JJ |
denotes |
single |
T14903 |
43550-43560 |
NN |
denotes |
inhalation |
T14904 |
43561-43563 |
IN |
denotes |
of |
T14905 |
43564-43566 |
NNP |
denotes |
FP |
T14906 |
43567-43568 |
-LRB- |
denotes |
( |
T14907 |
43568-43571 |
CD |
denotes |
500 |
T14908 |
43572-43574 |
NN |
denotes |
µg |
T14909 |
43574-43575 |
-RRB- |
denotes |
) |
T14910 |
43576-43579 |
MD |
denotes |
may |
T14911 |
43580-43584 |
VB |
denotes |
have |
T14912 |
43585-43595 |
JJ |
denotes |
comparable |
T14913 |
43596-43603 |
NNS |
denotes |
effects |
T14914 |
43603-43604 |
, |
denotes |
, |
T14915 |
43605-43607 |
IN |
denotes |
as |
T14916 |
43608-43610 |
PRP |
denotes |
it |
T14917 |
43611-43619 |
VBZ |
denotes |
provides |
T14918 |
43620-43626 |
NN |
denotes |
plasma |
T14919 |
43627-43633 |
NNS |
denotes |
levels |
T14920 |
43634-43640 |
IN |
denotes |
within |
T14921 |
43641-43642 |
DT |
denotes |
a |
T14922 |
43643-43651 |
JJ |
denotes |
relevant |
T14923 |
43652-43657 |
NN |
denotes |
range |
T14924 |
43658-43660 |
IN |
denotes |
of |
T14925 |
43661-43675 |
NNS |
denotes |
concentrations |
T14926 |
43676-43680 |
VBN |
denotes |
used |
T14927 |
43681-43683 |
TO |
denotes |
to |
T14928 |
43684-43692 |
VB |
denotes |
suppress |
T14929 |
43693-43697 |
NN |
denotes |
IL-4 |
T14930 |
43698-43711 |
NN |
denotes |
transcription |
T14931 |
43712-43714 |
IN |
denotes |
in |
T14932 |
43715-43718 |
PRP$ |
denotes |
our |
T14933 |
43719-43721 |
IN |
denotes |
in |
T14934 |
43722-43727 |
NN |
denotes |
vitro |
T14935 |
43728-43734 |
NN |
denotes |
system |
T14936 |
43735-43736 |
NNP |
denotes |
[ |
T14937 |
43736-43738 |
CD |
denotes |
37 |
T14938 |
43738-43739 |
NNP |
denotes |
] |
T14939 |
43739-43740 |
. |
denotes |
. |
T14940 |
43741-43742 |
DT |
denotes |
A |
T14941 |
43743-43748 |
JJR |
denotes |
lower |
T14942 |
43749-43753 |
NN |
denotes |
dose |
T14943 |
43754-43756 |
IN |
denotes |
of |
T14944 |
43757-43764 |
JJ |
denotes |
inhaled |
T14945 |
43765-43767 |
NNP |
denotes |
FP |
T14946 |
43768-43769 |
-LRB- |
denotes |
( |
T14947 |
43769-43772 |
CD |
denotes |
100 |
T14948 |
43773-43775 |
NN |
denotes |
µg |
T14949 |
43775-43776 |
-RRB- |
denotes |
) |
T14950 |
43777-43780 |
VBD |
denotes |
was |
T14951 |
43781-43784 |
RB |
denotes |
not |
T14952 |
43785-43794 |
JJ |
denotes |
effective |
T14953 |
43794-43795 |
, |
denotes |
, |
T14954 |
43796-43799 |
CC |
denotes |
but |
T14955 |
43800-43806 |
NN |
denotes |
plasma |
T14956 |
43807-43821 |
NNS |
denotes |
concentrations |
T14957 |
43822-43825 |
MD |
denotes |
may |
T14958 |
43826-43828 |
VB |
denotes |
be |
T14959 |
43829-43834 |
IN |
denotes |
below |
T14960 |
43835-43840 |
DT |
denotes |
those |
T14961 |
43841-43849 |
VBN |
denotes |
required |
T14962 |
43850-43853 |
IN |
denotes |
for |
T14963 |
43854-43860 |
JJ |
denotes |
GATA-3 |
T14964 |
43861-43871 |
NN |
denotes |
inhibition |
T14965 |
43871-43872 |
. |
denotes |
. |
T14966 |
43873-43880 |
RB |
denotes |
However |
T14967 |
43880-43881 |
, |
denotes |
, |
T14968 |
43882-43884 |
PRP |
denotes |
it |
T14969 |
43885-43887 |
VBZ |
denotes |
is |
T14970 |
43888-43894 |
JJ |
denotes |
likely |
T14971 |
43895-43899 |
IN |
denotes |
that |
T14972 |
43900-43903 |
DT |
denotes |
the |
T14973 |
43904-43910 |
JJR |
denotes |
higher |
T14974 |
43911-43925 |
NNS |
denotes |
concentrations |
T14975 |
43926-43928 |
IN |
denotes |
of |
T14976 |
43929-43931 |
NNP |
denotes |
FP |
T14977 |
43932-43934 |
IN |
denotes |
in |
T14978 |
43935-43938 |
DT |
denotes |
the |
T14979 |
43939-43946 |
NNS |
denotes |
airways |
T14980 |
43947-43952 |
IN |
denotes |
after |
T14981 |
43953-43960 |
JJ |
denotes |
inhaled |
T14982 |
43961-43975 |
NN |
denotes |
administration |
T14983 |
43976-43981 |
MD |
denotes |
would |
T14984 |
43982-43984 |
VB |
denotes |
be |
T14985 |
43985-43994 |
JJ |
denotes |
effective |
T14986 |
43995-43997 |
IN |
denotes |
in |
T14987 |
43998-44008 |
VBG |
denotes |
inhibiting |
T14988 |
44009-44015 |
NN |
denotes |
GATA-3 |
T14989 |
44016-44018 |
IN |
denotes |
in |
T14990 |
44019-44025 |
NN |
denotes |
airway |
T14991 |
44026-44027 |
NNP |
denotes |
T |
T14992 |
44028-44033 |
NNS |
denotes |
cells |
T14993 |
44034-44036 |
IN |
denotes |
of |
T14994 |
44037-44043 |
NN |
denotes |
asthma |
T14995 |
44044-44052 |
NNS |
denotes |
patients |
T14996 |
44052-44053 |
. |
denotes |
. |
T14997 |
44054-44057 |
DT |
denotes |
The |
T14998 |
44058-44063 |
NN |
denotes |
study |
T14999 |
44064-44066 |
IN |
denotes |
of |
T15000 |
44067-44072 |
NNS |
denotes |
PBMCs |
T15001 |
44073-44077 |
IN |
denotes |
from |
T15002 |
44078-44084 |
NN |
denotes |
asthma |
T15003 |
44085-44093 |
NNS |
denotes |
patients |
T15004 |
44094-44101 |
VBN |
denotes |
treated |
T15005 |
44102-44106 |
IN |
denotes |
with |
T15006 |
44107-44114 |
JJ |
denotes |
inhaled |
T15007 |
44115-44129 |
JJ |
denotes |
corticosteroid |
T15008 |
44130-44137 |
NN |
denotes |
therapy |
T15009 |
44138-44145 |
RB |
denotes |
clearly |
T15010 |
44146-44158 |
VBZ |
denotes |
demonstrates |
T15011 |
44159-44163 |
IN |
denotes |
that |
T15012 |
44164-44169 |
DT |
denotes |
these |
T15013 |
44170-44179 |
JJ |
denotes |
molecular |
T15014 |
44180-44190 |
NNS |
denotes |
mechanisms |
T15015 |
44191-44194 |
VBP |
denotes |
are |
T15016 |
44195-44201 |
JJ |
denotes |
likely |
T15017 |
44202-44204 |
TO |
denotes |
to |
T15018 |
44205-44209 |
RB |
denotes |
also |
T15019 |
44210-44215 |
VB |
denotes |
occur |
T15020 |
44216-44218 |
IN |
denotes |
in |
T15021 |
44219-44227 |
NNS |
denotes |
patients |
T15022 |
44228-44230 |
IN |
denotes |
at |
T15023 |
44231-44242 |
JJ |
denotes |
therapeutic |
T15024 |
44243-44248 |
NNS |
denotes |
doses |
T15025 |
44249-44251 |
IN |
denotes |
of |
T15026 |
44252-44259 |
JJ |
denotes |
inhaled |
T15027 |
44260-44275 |
NNS |
denotes |
corticosteroids |
T15028 |
44275-44276 |
. |
denotes |
. |
T15029 |
44277-44279 |
IN |
denotes |
In |
T15030 |
44280-44288 |
NN |
denotes |
addition |
T15031 |
44288-44289 |
, |
denotes |
, |
T15032 |
44290-44298 |
JJ |
denotes |
previous |
T15033 |
44299-44306 |
NNS |
denotes |
studies |
T15034 |
44307-44311 |
VBP |
denotes |
have |
T15035 |
44312-44317 |
VBN |
denotes |
shown |
T15036 |
44318-44322 |
IN |
denotes |
that |
T15037 |
44323-44338 |
NNS |
denotes |
corticosteroids |
T15038 |
44339-44342 |
MD |
denotes |
can |
T15039 |
44343-44351 |
VB |
denotes |
suppress |
T15040 |
44352-44356 |
NN |
denotes |
IL-4 |
T15041 |
44357-44360 |
CC |
denotes |
and |
T15042 |
44361-44365 |
NN |
denotes |
IL-5 |
T15043 |
44366-44373 |
NN |
denotes |
release |
T15044 |
44374-44378 |
IN |
denotes |
from |
T15045 |
44379-44389 |
JJ |
denotes |
peripheral |
T15046 |
44390-44395 |
NN |
denotes |
blood |
T15047 |
44396-44401 |
NNS |
denotes |
cells |
T15048 |
44402-44404 |
IN |
denotes |
of |
T15049 |
44405-44411 |
NN |
denotes |
asthma |
T15050 |
44412-44420 |
NNS |
denotes |
patients |
T15051 |
44421-44423 |
IN |
denotes |
in |
T15052 |
44424-44429 |
NN |
denotes |
vitro |
T15053 |
44430-44433 |
CC |
denotes |
and |
T15054 |
44434-44436 |
IN |
denotes |
in |
T15055 |
44437-44441 |
NN |
denotes |
vivo |
T15056 |
44442-44443 |
NNP |
denotes |
[ |
T15057 |
44443-44445 |
CD |
denotes |
40 |
T15058 |
44445-44446 |
NNP |
denotes |
] |
T15059 |
44447-44448 |
NNP |
denotes |
[ |
T15060 |
44448-44450 |
CD |
denotes |
42 |
T15061 |
44450-44451 |
NNP |
denotes |
] |
T15062 |
44451-44452 |
. |
denotes |
. |
T15063 |
44453-44455 |
IN |
denotes |
In |
T15064 |
44456-44463 |
NN |
denotes |
summary |
T15065 |
44463-44464 |
, |
denotes |
, |
T15066 |
44465-44468 |
PRP$ |
denotes |
our |
T15067 |
44469-44473 |
NNS |
denotes |
data |
T15068 |
44474-44481 |
VBP |
denotes |
provide |
T15069 |
44482-44490 |
NN |
denotes |
evidence |
T15070 |
44491-44494 |
IN |
denotes |
for |
T15071 |
44495-44496 |
DT |
denotes |
a |
T15072 |
44497-44502 |
NN |
denotes |
novel |
T15073 |
44503-44509 |
NN |
denotes |
action |
T15074 |
44510-44512 |
IN |
denotes |
of |
T15075 |
44513-44528 |
NNS |
denotes |
corticosteroids |
T15076 |
44528-44529 |
: |
denotes |
: |
T15077 |
44530-44541 |
NN |
denotes |
suppression |
T15078 |
44542-44544 |
IN |
denotes |
of |
T15079 |
44545-44553 |
JJ |
denotes |
allergic |
T15080 |
44554-44566 |
NN |
denotes |
inflammation |
T15081 |
44567-44574 |
IN |
denotes |
through |
T15082 |
44575-44576 |
DT |
denotes |
a |
T15083 |
44577-44582 |
JJ |
denotes |
rapid |
T15084 |
44583-44593 |
JJ |
denotes |
inhibitory |
T15085 |
44594-44600 |
NN |
denotes |
effect |
T15086 |
44601-44603 |
IN |
denotes |
on |
T15087 |
44604-44610 |
JJ |
denotes |
GATA-3 |
T15088 |
44611-44618 |
JJ |
denotes |
nuclear |
T15089 |
44619-44632 |
NN |
denotes |
translocation |
T15090 |
44633-44635 |
IN |
denotes |
by |
T15091 |
44636-44648 |
JJ |
denotes |
preferential |
T15092 |
44649-44656 |
JJ |
denotes |
binding |
T15093 |
44657-44659 |
TO |
denotes |
to |
T15094 |
44660-44663 |
DT |
denotes |
the |
T15095 |
44664-44670 |
VBN |
denotes |
shared |
T15096 |
44671-44678 |
JJ |
denotes |
nuclear |
T15097 |
44679-44685 |
NN |
denotes |
import |
T15098 |
44686-44693 |
NN |
denotes |
protein |
T15099 |
44694-44704 |
NN |
denotes |
importin-α |
T15100 |
44705-44708 |
CC |
denotes |
and |
T15101 |
44709-44711 |
IN |
denotes |
by |
T15102 |
44712-44713 |
DT |
denotes |
a |
T15103 |
44714-44720 |
JJ |
denotes |
second |
T15104 |
44721-44730 |
NN |
denotes |
mechanism |
T15105 |
44731-44740 |
VBG |
denotes |
involving |
T15106 |
44741-44750 |
VBN |
denotes |
increased |
T15107 |
44751-44760 |
NN |
denotes |
synthesis |
T15108 |
44761-44763 |
IN |
denotes |
of |
T15109 |
44764-44769 |
NNP |
denotes |
MKP-1 |
T15110 |
44769-44770 |
, |
denotes |
, |
T15111 |
44771-44776 |
WDT |
denotes |
which |
T15112 |
44777-44785 |
VBZ |
denotes |
inhibits |
T15113 |
44786-44789 |
CD |
denotes |
p38 |
T15114 |
44790-44794 |
NNP |
denotes |
MAPK |
T15115 |
44794-44795 |
, |
denotes |
, |
T15116 |
44796-44800 |
RB |
denotes |
thus |
T15117 |
44801-44811 |
VBG |
denotes |
preventing |
T15118 |
44812-44815 |
DT |
denotes |
the |
T15119 |
44816-44831 |
NN |
denotes |
phosphorylation |
T15120 |
44832-44834 |
IN |
denotes |
of |
T15121 |
44835-44841 |
NN |
denotes |
GATA-3 |
T15122 |
44842-44846 |
WDT |
denotes |
that |
T15123 |
44847-44849 |
VBZ |
denotes |
is |
T15124 |
44850-44859 |
JJ |
denotes |
necessary |
T15125 |
44860-44863 |
IN |
denotes |
for |
T15126 |
44864-44871 |
JJ |
denotes |
nuclear |
T15127 |
44872-44885 |
NN |
denotes |
translocation |
T15128 |
44886-44888 |
IN |
denotes |
of |
T15129 |
44889-44895 |
NN |
denotes |
GATA-3 |
T15130 |
44895-44896 |
. |
denotes |
. |
T15131 |
44897-44902 |
DT |
denotes |
These |
T15132 |
44903-44906 |
CD |
denotes |
two |
T15133 |
44907-44917 |
NNS |
denotes |
mechanisms |
T15134 |
44918-44921 |
VBP |
denotes |
are |
T15135 |
44922-44928 |
JJ |
denotes |
likely |
T15136 |
44929-44931 |
TO |
denotes |
to |
T15137 |
44932-44934 |
VB |
denotes |
be |
T15138 |
44935-44946 |
JJ |
denotes |
synergistic |
T15139 |
44946-44947 |
, |
denotes |
, |
T15140 |
44948-44958 |
VBG |
denotes |
accounting |
T15141 |
44959-44962 |
IN |
denotes |
for |
T15142 |
44963-44966 |
DT |
denotes |
the |
T15143 |
44967-44972 |
JJ |
denotes |
rapid |
T15144 |
44973-44976 |
CC |
denotes |
and |
T15145 |
44977-44983 |
JJ |
denotes |
potent |
T15146 |
44984-44990 |
NN |
denotes |
effect |
T15147 |
44991-44993 |
IN |
denotes |
of |
T15148 |
44994-45009 |
NNS |
denotes |
corticosteroids |
T15149 |
45010-45012 |
IN |
denotes |
on |
T15150 |
45013-45021 |
JJ |
denotes |
allergic |
T15151 |
45022-45034 |
NN |
denotes |
inflammation |
T15152 |
45034-45035 |
. |
denotes |
. |
T15153 |
45036-45040 |
DT |
denotes |
This |
T15154 |
45041-45043 |
VBZ |
denotes |
is |
T15155 |
45044-45055 |
VBN |
denotes |
exemplified |
T15156 |
45056-45058 |
IN |
denotes |
by |
T15157 |
45059-45062 |
DT |
denotes |
the |
T15158 |
45063-45068 |
JJ |
denotes |
rapid |
T15159 |
45069-45079 |
JJ |
denotes |
inhibitory |
T15160 |
45080-45086 |
NN |
denotes |
effect |
T15161 |
45087-45089 |
IN |
denotes |
of |
T15162 |
45090-45097 |
JJ |
denotes |
topical |
T15163 |
45098-45113 |
NNS |
denotes |
corticosteroids |
T15164 |
45114-45116 |
IN |
denotes |
on |
T15165 |
45117-45122 |
JJ |
denotes |
nasal |
T15166 |
45123-45126 |
JJ |
denotes |
Th2 |
T15167 |
45127-45135 |
NN |
denotes |
cytokine |
T15168 |
45136-45143 |
NN |
denotes |
release |
T15169 |
45144-45149 |
IN |
denotes |
after |
T15170 |
45150-45158 |
NN |
denotes |
allergen |
T15171 |
45159-45170 |
NN |
denotes |
provocation |
T15172 |
45171-45173 |
IN |
denotes |
in |
T15173 |
45174-45185 |
NNS |
denotes |
individuals |
T15174 |
45186-45190 |
IN |
denotes |
with |
T15175 |
45191-45199 |
JJ |
denotes |
seasonal |
T15176 |
45200-45208 |
JJ |
denotes |
allergic |
T15177 |
45209-45217 |
NN |
denotes |
rhinitis |
T15178 |
45218-45219 |
-LRB- |
denotes |
( |
T15179 |
45219-45222 |
NN |
denotes |
hay |
T15180 |
45223-45228 |
NN |
denotes |
fever |
T15181 |
45228-45229 |
-RRB- |
denotes |
) |
T15182 |
45230-45231 |
NNP |
denotes |
[ |
T15183 |
45231-45233 |
CD |
denotes |
43 |
T15184 |
45233-45234 |
NNP |
denotes |
] |
T15185 |
45234-45235 |
. |
denotes |
. |
T15186 |
45236-45246 |
NNP |
denotes |
Prevention |
T15187 |
45247-45249 |
IN |
denotes |
of |
T15188 |
45250-45264 |
JJ |
denotes |
phospho-GATA-3 |
T15189 |
45265-45276 |
NN |
denotes |
interaction |
T15190 |
45277-45281 |
IN |
denotes |
with |
T15191 |
45282-45292 |
NN |
denotes |
importin-α |
T15192 |
45293-45296 |
MD |
denotes |
may |
T15193 |
45297-45304 |
VB |
denotes |
provide |
T15194 |
45305-45306 |
DT |
denotes |
a |
T15195 |
45307-45310 |
JJ |
denotes |
new |
T15196 |
45311-45319 |
NN |
denotes |
approach |
T15197 |
45320-45323 |
IN |
denotes |
for |
T15198 |
45324-45327 |
DT |
denotes |
the |
T15199 |
45328-45339 |
NN |
denotes |
development |
T15200 |
45340-45342 |
IN |
denotes |
of |
T15201 |
45343-45348 |
NN |
denotes |
novel |
T15202 |
45349-45358 |
NNS |
denotes |
therapies |
T15203 |
45359-45362 |
IN |
denotes |
for |
T15204 |
45363-45366 |
DT |
denotes |
the |
T15205 |
45367-45376 |
NN |
denotes |
treatment |
T15206 |
45377-45379 |
IN |
denotes |
of |
T15207 |
45380-45388 |
JJ |
denotes |
allergic |
T15208 |
45389-45397 |
NNS |
denotes |
diseases |
T15209 |
45397-45398 |
. |
denotes |
. |
R10235 |
T11922 |
T11924 |
det |
The,Effect |
R10236 |
T11923 |
T11924 |
compound |
Inhibitory,Effect |
R10237 |
T11924 |
T11945 |
nsubj |
Effect,demonstrated |
R10238 |
T11925 |
T11924 |
prep |
of,Effect |
R10239 |
T11926 |
T11925 |
pobj |
Corticosteroids,of |
R10240 |
T11927 |
T11924 |
prep |
on,Effect |
R10241 |
T11928 |
T11930 |
compound |
GATA-3,Localization |
R10242 |
T11929 |
T11930 |
compound |
Nuclear,Localization |
R10243 |
T11930 |
T11927 |
pobj |
Localization,on |
R10244 |
T11931 |
T11930 |
prep |
in,Localization |
R10245 |
T11932 |
T11933 |
compound |
Primary,T |
R10246 |
T11933 |
T11934 |
compound |
T,Lymphocytes |
R10247 |
T11934 |
T11936 |
compound |
Lymphocytes,Vivo |
R10248 |
T11935 |
T11936 |
compound |
Ex,Vivo |
R10249 |
T11936 |
T11931 |
pobj |
Vivo,in |
R10250 |
T11937 |
T11924 |
cc |
and,Effect |
R10251 |
T11938 |
T11945 |
prep |
In,demonstrated |
R10252 |
T11939 |
T11940 |
compound |
Vivo,Treatment |
R10253 |
T11940 |
T11938 |
pobj |
Treatment,In |
R10254 |
T11941 |
T11940 |
prep |
with,Treatment |
R10255 |
T11942 |
T11944 |
compound |
FP,vivo |
R10256 |
T11943 |
T11944 |
nmod |
ex,vivo |
R10257 |
T11944 |
T11945 |
nsubj |
vivo,demonstrated |
R10258 |
T11945 |
T11945 |
ROOT |
demonstrated,demonstrated |
R10259 |
T11946 |
T11948 |
det |
a,decrease |
R10260 |
T11947 |
T11948 |
amod |
concentration-dependent,decrease |
R10261 |
T11948 |
T11945 |
dobj |
decrease,demonstrated |
R10262 |
T11949 |
T11948 |
prep |
in,decrease |
R10263 |
T11950 |
T11952 |
det |
the,interaction |
R10264 |
T11951 |
T11952 |
amod |
direct,interaction |
R10265 |
T11952 |
T11949 |
pobj |
interaction,in |
R10266 |
T11953 |
T11952 |
prep |
between,interaction |
R10267 |
T11954 |
T11953 |
pobj |
phospho-GATA-3,between |
R10268 |
T11955 |
T11954 |
cc |
and,phospho-GATA-3 |
R10269 |
T11956 |
T11954 |
conj |
importin-α,phospho-GATA-3 |
R10270 |
T11957 |
T11956 |
prep |
in,importin-α |
R10271 |
T11958 |
T11957 |
pobj |
PBMCs,in |
R10272 |
T11959 |
T11954 |
prep |
from,phospho-GATA-3 |
R10273 |
T11960 |
T11959 |
pobj |
patients,from |
R10274 |
T11961 |
T11960 |
prep |
with,patients |
R10275 |
T11962 |
T11965 |
compound |
asthma,6A |
R10276 |
T11963 |
T11964 |
punct |
(,Figure |
R10277 |
T11964 |
T11965 |
compound |
Figure,6A |
R10278 |
T11965 |
T11961 |
pobj |
6A,with |
R10279 |
T11966 |
T11965 |
cc |
and,6A |
R10280 |
T11967 |
T11965 |
conj |
6B,6A |
R10281 |
T11968 |
T11967 |
punct |
),6B |
R10282 |
T11969 |
T11965 |
punct |
",",6A |
R10283 |
T11970 |
T11973 |
nsubjpass |
which,inhibited |
R10284 |
T11971 |
T11973 |
auxpass |
was,inhibited |
R10285 |
T11972 |
T11973 |
advmod |
significantly,inhibited |
R10286 |
T11973 |
T11960 |
relcl |
inhibited,patients |
R10287 |
T11974 |
T11973 |
prep |
at,inhibited |
R10288 |
T11975 |
T11979 |
nummod |
10,FP |
R10289 |
T11976 |
T11979 |
nummod |
−,FP |
R10290 |
T11977 |
T11979 |
nummod |
12,FP |
R10291 |
T11978 |
T11979 |
compound |
M,FP |
R10292 |
T11979 |
T11974 |
pobj |
FP,at |
R10293 |
T11980 |
T11979 |
punct |
(,FP |
R10294 |
T11981 |
T11982 |
nmod |
p,< |
R10295 |
T11982 |
T11983 |
nmod |
<,0.001 |
R10296 |
T11983 |
T11979 |
appos |
0.001,FP |
R10297 |
T11984 |
T11983 |
punct |
",",0.001 |
R10298 |
T11985 |
T11983 |
conj |
ANOVA,0.001 |
R10299 |
T11986 |
T11985 |
cc |
and,ANOVA |
R10300 |
T11987 |
T11988 |
compound |
Newman-Keuls,test |
R10301 |
T11988 |
T11985 |
conj |
test,ANOVA |
R10302 |
T11989 |
T11988 |
punct |
),test |
R10303 |
T11990 |
T11973 |
cc |
and,inhibited |
R10304 |
T11991 |
T11992 |
advmod |
completely,attenuated |
R10305 |
T11992 |
T11973 |
conj |
attenuated,inhibited |
R10306 |
T11993 |
T11992 |
prep |
by,attenuated |
R10307 |
T11994 |
T11998 |
nummod |
10,FP |
R10308 |
T11995 |
T11996 |
quantmod |
−,8 |
R10309 |
T11996 |
T11998 |
nummod |
8,FP |
R10310 |
T11997 |
T11998 |
compound |
M,FP |
R10311 |
T11998 |
T12001 |
nmod |
FP,< |
R10312 |
T11999 |
T12001 |
punct |
(,< |
R10313 |
T12000 |
T12001 |
nmod |
p,< |
R10314 |
T12001 |
T11993 |
pobj |
<,by |
R10315 |
T12002 |
T12001 |
appos |
0.001,< |
R10316 |
T12003 |
T12001 |
punct |
",",< |
R10317 |
T12004 |
T12001 |
conj |
ANOVA,< |
R10318 |
T12005 |
T12004 |
cc |
and,ANOVA |
R10319 |
T12006 |
T12007 |
compound |
Newman-Keuls,test |
R10320 |
T12007 |
T12004 |
conj |
test,ANOVA |
R10321 |
T12008 |
T12001 |
punct |
),< |
R10322 |
T12009 |
T11945 |
punct |
.,demonstrated |
R10323 |
T12010 |
T12015 |
poss |
Our,studies |
R10324 |
T12011 |
T12015 |
amod |
previous,studies |
R10325 |
T12012 |
T12015 |
compound |
T,studies |
R10326 |
T12013 |
T12014 |
compound |
cell,line |
R10327 |
T12014 |
T12015 |
compound |
line,studies |
R10328 |
T12015 |
T12016 |
nsubj |
studies,indicated |
R10329 |
T12016 |
T12016 |
ROOT |
indicated,indicated |
R10330 |
T12017 |
T12023 |
mark |
that,suppresses |
R10331 |
T12018 |
T12023 |
nsubj |
10,suppresses |
R10332 |
T12019 |
T12023 |
dep |
−,suppresses |
R10333 |
T12020 |
T12023 |
dep |
12,suppresses |
R10334 |
T12021 |
T12022 |
compound |
M,FP |
R10335 |
T12022 |
T12023 |
nsubj |
FP,suppresses |
R10336 |
T12023 |
T12016 |
ccomp |
suppresses,indicated |
R10337 |
T12024 |
T12023 |
dobj |
IL-4,suppresses |
R10338 |
T12025 |
T12024 |
cc |
and,IL-4 |
R10339 |
T12026 |
T12028 |
nummod |
-5,expression |
R10340 |
T12027 |
T12028 |
compound |
gene,expression |
R10341 |
T12028 |
T12024 |
conj |
expression,IL-4 |
R10342 |
T12029 |
T12028 |
cc |
and,expression |
R10343 |
T12030 |
T12016 |
conj |
attenuated,indicated |
R10344 |
T12031 |
T12032 |
det |
the,interaction |
R10345 |
T12032 |
T12030 |
dobj |
interaction,attenuated |
R10346 |
T12033 |
T12032 |
prep |
of,interaction |
R10347 |
T12034 |
T12033 |
pobj |
GATA-3,of |
R10348 |
T12035 |
T12032 |
prep |
with,interaction |
R10349 |
T12036 |
T12035 |
pobj |
importin-α,with |
R10350 |
T12037 |
T12038 |
punct |
(,see |
R10351 |
T12038 |
T12016 |
parataxis |
see,indicated |
R10352 |
T12039 |
T12038 |
npadvmod |
Figures,see |
R10353 |
T12040 |
T12043 |
nmod |
1D,) |
R10354 |
T12041 |
T12040 |
cc |
and,1D |
R10355 |
T12042 |
T12040 |
conj |
2,1D |
R10356 |
T12043 |
T12038 |
punct |
),see |
R10357 |
T12044 |
T12016 |
punct |
.,indicated |
R10358 |
T12045 |
T12046 |
det |
This,concentration |
R10359 |
T12046 |
T12047 |
nsubj |
concentration,is |
R10360 |
T12047 |
T12047 |
ROOT |
is,is |
R10361 |
T12048 |
T12047 |
acomp |
close,is |
R10362 |
T12049 |
T12050 |
aux |
to,peak |
R10363 |
T12050 |
T12047 |
xcomp |
peak,is |
R10364 |
T12051 |
T12052 |
compound |
plasma,levels |
R10365 |
T12052 |
T12050 |
dobj |
levels,peak |
R10366 |
T12053 |
T12052 |
acl |
obtained,levels |
R10367 |
T12054 |
T12053 |
prep |
from,obtained |
R10368 |
T12055 |
T12056 |
amod |
asthmatic,patients |
R10369 |
T12056 |
T12054 |
pobj |
patients,from |
R10370 |
T12057 |
T12056 |
acl |
treated,patients |
R10371 |
T12058 |
T12057 |
prep |
with,treated |
R10372 |
T12059 |
T12060 |
amod |
inhaled,FP |
R10373 |
T12060 |
T12065 |
nmod |
FP,[ |
R10374 |
T12061 |
T12060 |
punct |
(,FP |
R10375 |
T12062 |
T12063 |
nummod |
500,µg |
R10376 |
T12063 |
T12060 |
appos |
µg,FP |
R10377 |
T12064 |
T12065 |
punct |
),[ |
R10378 |
T12065 |
T12067 |
nmod |
[,] |
R10379 |
T12066 |
T12067 |
nummod |
27,] |
R10380 |
T12067 |
T12058 |
pobj |
],with |
R10381 |
T12068 |
T12047 |
punct |
.,is |
R10382 |
T12069 |
T12070 |
compound |
Inhaled,FP |
R10383 |
T12070 |
T12082 |
nsubj |
FP,reduced |
R10384 |
T12071 |
T12073 |
punct |
(,µg |
R10385 |
T12072 |
T12073 |
nummod |
500,µg |
R10386 |
T12073 |
T12070 |
appos |
µg,FP |
R10387 |
T12074 |
T12073 |
punct |
),µg |
R10388 |
T12075 |
T12070 |
appos |
treatment,FP |
R10389 |
T12076 |
T12075 |
prep |
of,treatment |
R10390 |
T12077 |
T12080 |
nummod |
seven,patients |
R10391 |
T12078 |
T12080 |
amod |
steroid-naive,patients |
R10392 |
T12079 |
T12080 |
compound |
asthma,patients |
R10393 |
T12080 |
T12076 |
pobj |
patients,of |
R10394 |
T12081 |
T12082 |
advmod |
significantly,reduced |
R10395 |
T12082 |
T12082 |
ROOT |
reduced,reduced |
R10396 |
T12083 |
T12082 |
dobj |
GATA-3,reduced |
R10397 |
T12084 |
T12085 |
amod |
importin-α,interaction |
R10398 |
T12085 |
T12083 |
appos |
interaction,GATA-3 |
R10399 |
T12086 |
T12085 |
prep |
in,interaction |
R10400 |
T12087 |
T12086 |
pobj |
vivo,in |
R10401 |
T12088 |
T12082 |
prep |
in,reduced |
R10402 |
T12089 |
T12091 |
det |
a,manner |
R10403 |
T12090 |
T12091 |
amod |
time-dependent,manner |
R10404 |
T12091 |
T12088 |
pobj |
manner,in |
R10405 |
T12092 |
T12082 |
punct |
.,reduced |
R10406 |
T12093 |
T12094 |
nsubj |
This,produced |
R10407 |
T12094 |
T12094 |
ROOT |
produced,produced |
R10408 |
T12095 |
T12096 |
det |
a,> |
R10409 |
T12096 |
T12099 |
compound |
>,decrease |
R10410 |
T12097 |
T12098 |
nummod |
90,% |
R10411 |
T12098 |
T12099 |
compound |
%,decrease |
R10412 |
T12099 |
T12094 |
dobj |
decrease,produced |
R10413 |
T12100 |
T12099 |
prep |
in,decrease |
R10414 |
T12101 |
T12100 |
pobj |
GATA-3,in |
R10415 |
T12102 |
T12103 |
compound |
importin-α,association |
R10416 |
T12103 |
T12099 |
appos |
association,decrease |
R10417 |
T12104 |
T12099 |
prep |
at,decrease |
R10418 |
T12105 |
T12106 |
nummod |
2,h |
R10419 |
T12106 |
T12104 |
pobj |
h,at |
R10420 |
T12107 |
T12113 |
punct |
(,] |
R10421 |
T12108 |
T12113 |
amod |
median,] |
R10422 |
T12109 |
T12113 |
compound |
[,] |
R10423 |
T12110 |
T12111 |
nummod |
95,% |
R10424 |
T12111 |
T12113 |
compound |
%,] |
R10425 |
T12112 |
T12113 |
compound |
CI,] |
R10426 |
T12113 |
T12099 |
appos |
],decrease |
R10427 |
T12114 |
T12113 |
punct |
",",] |
R10428 |
T12115 |
T12117 |
nummod |
"13,494","6,828" |
R10429 |
T12116 |
T12117 |
compound |
[,"6,828" |
R10430 |
T12117 |
T12113 |
appos |
"6,828",] |
R10431 |
T12118 |
T12119 |
compound |
"17,829",] |
R10432 |
T12119 |
T12113 |
conj |
],] |
R10433 |
T12120 |
T12119 |
cc |
versus,] |
R10434 |
T12121 |
T12127 |
dep |
879,p |
R10435 |
T12122 |
T12127 |
ccomp |
[,p |
R10436 |
T12123 |
T12122 |
nummod |
597,[ |
R10437 |
T12124 |
T12122 |
nummod |
"1,165",[ |
R10438 |
T12125 |
T12125 |
ROOT |
],] |
R10439 |
T12126 |
T12127 |
punct |
;,p |
R10440 |
T12127 |
T12113 |
parataxis |
p,] |
R10441 |
T12128 |
T12127 |
advmod |
<,p |
R10442 |
T12129 |
T12132 |
nummod |
0.05,analysis |
R10443 |
T12130 |
T12132 |
poss |
Friedman,analysis |
R10444 |
T12131 |
T12130 |
case |
's,Friedman |
R10445 |
T12132 |
T12128 |
appos |
analysis,< |
R10446 |
T12133 |
T12128 |
punct |
),< |
R10447 |
T12134 |
T12127 |
punct |
.,p |
R10448 |
T12135 |
T12140 |
advmod |
However,reach |
R10449 |
T12136 |
T12140 |
punct |
",",reach |
R10450 |
T12137 |
T12140 |
nsubj |
this,reach |
R10451 |
T12138 |
T12140 |
aux |
did,reach |
R10452 |
T12139 |
T12140 |
neg |
not,reach |
R10453 |
T12140 |
T12140 |
ROOT |
reach,reach |
R10454 |
T12141 |
T12140 |
dobj |
significance,reach |
R10455 |
T12142 |
T12140 |
advcl |
using,reach |
R10456 |
T12143 |
T12146 |
poss |
Wilcoxon,analysis |
R10457 |
T12144 |
T12143 |
case |
's,Wilcoxon |
R10458 |
T12145 |
T12146 |
amod |
post-test,analysis |
R10459 |
T12146 |
T12142 |
dobj |
analysis,using |
R10460 |
T12147 |
T12153 |
punct |
(,due |
R10461 |
T12148 |
T12153 |
nsubj |
W,due |
R10462 |
T12149 |
T12150 |
punct |
=,6.00 |
R10463 |
T12150 |
T12148 |
nummod |
6.00,W |
R10464 |
T12151 |
T12148 |
punct |
),W |
R10465 |
T12152 |
T12153 |
advmod |
probably,due |
R10466 |
T12153 |
T12140 |
advcl |
due,reach |
R10467 |
T12154 |
T12153 |
pcomp |
to,due |
R10468 |
T12155 |
T12156 |
amod |
low,numbers |
R10469 |
T12156 |
T12154 |
pobj |
numbers,to |
R10470 |
T12157 |
T12156 |
prep |
of,numbers |
R10471 |
T12158 |
T12157 |
pobj |
participants,of |
R10472 |
T12159 |
T12140 |
punct |
.,reach |
R10473 |
T12160 |
T12161 |
amod |
Similar,results |
R10474 |
T12161 |
T12163 |
nsubjpass |
results,observed |
R10475 |
T12162 |
T12163 |
auxpass |
were,observed |
R10476 |
T12163 |
T12163 |
ROOT |
observed,observed |
R10477 |
T12164 |
T12169 |
advmod |
when,measured |
R10478 |
T12165 |
T12169 |
nsubjpass |
GATA-3,measured |
R10479 |
T12166 |
T12167 |
amod |
importin-α,association |
R10480 |
T12167 |
T12165 |
appos |
association,GATA-3 |
R10481 |
T12168 |
T12169 |
auxpass |
was,measured |
R10482 |
T12169 |
T12163 |
advcl |
measured,observed |
R10483 |
T12170 |
T12172 |
punct |
(,6C |
R10484 |
T12171 |
T12172 |
compound |
Figure,6C |
R10485 |
T12172 |
T12169 |
dobj |
6C,measured |
R10486 |
T12173 |
T12172 |
cc |
and,6C |
R10487 |
T12174 |
T12172 |
conj |
6D,6C |
R10488 |
T12175 |
T12172 |
punct |
),6C |
R10489 |
T12176 |
T12163 |
punct |
.,observed |
R10490 |
T12177 |
T12179 |
det |
The,dose |
R10491 |
T12178 |
T12179 |
amod |
lower,dose |
R10492 |
T12179 |
T12186 |
nsubj |
dose,was |
R10493 |
T12180 |
T12179 |
prep |
of,dose |
R10494 |
T12181 |
T12180 |
pobj |
FP,of |
R10495 |
T12182 |
T12181 |
punct |
(,FP |
R10496 |
T12183 |
T12184 |
nummod |
100,µg |
R10497 |
T12184 |
T12181 |
appos |
µg,FP |
R10498 |
T12185 |
T12184 |
punct |
),µg |
R10499 |
T12186 |
T12186 |
ROOT |
was,was |
R10500 |
T12187 |
T12186 |
neg |
not,was |
R10501 |
T12188 |
T12186 |
acomp |
effective,was |
R10502 |
T12189 |
T12186 |
punct |
.,was |
R10503 |
T12190 |
T12192 |
det |
The,interaction |
R10504 |
T12191 |
T12192 |
amod |
attenuated,interaction |
R10505 |
T12192 |
T12197 |
nsubj |
interaction,result |
R10506 |
T12193 |
T12192 |
prep |
of,interaction |
R10507 |
T12194 |
T12193 |
pobj |
GATA-3,of |
R10508 |
T12195 |
T12197 |
aux |
did,result |
R10509 |
T12196 |
T12197 |
neg |
not,result |
R10510 |
T12197 |
T12197 |
ROOT |
result,result |
R10511 |
T12198 |
T12197 |
prep |
from,result |
R10512 |
T12199 |
T12201 |
det |
the,recycling |
R10513 |
T12200 |
T12201 |
amod |
defective,recycling |
R10514 |
T12201 |
T12198 |
pobj |
recycling,from |
R10515 |
T12202 |
T12201 |
prep |
of,recycling |
R10516 |
T12203 |
T12202 |
pobj |
importin-α,of |
R10517 |
T12204 |
T12197 |
punct |
",",result |
R10518 |
T12205 |
T12197 |
prep |
as,result |
R10519 |
T12206 |
T12208 |
det |
a,decrease |
R10520 |
T12207 |
T12208 |
amod |
significant,decrease |
R10521 |
T12208 |
T12205 |
pobj |
decrease,as |
R10522 |
T12209 |
T12208 |
prep |
in,decrease |
R10523 |
T12210 |
T12211 |
det |
the,abundance |
R10524 |
T12211 |
T12209 |
pobj |
abundance,in |
R10525 |
T12212 |
T12211 |
prep |
of,abundance |
R10526 |
T12213 |
T12212 |
pobj |
importin-α,of |
R10527 |
T12214 |
T12208 |
prep |
in,decrease |
R10528 |
T12215 |
T12217 |
det |
the,pool |
R10529 |
T12216 |
T12217 |
amod |
cytoplasmic,pool |
R10530 |
T12217 |
T12214 |
pobj |
pool,in |
R10531 |
T12218 |
T12220 |
auxpass |
was,detected |
R10532 |
T12219 |
T12220 |
neg |
not,detected |
R10533 |
T12220 |
T12197 |
conj |
detected,result |
R10534 |
T12221 |
T12222 |
punct |
(,Figure |
R10535 |
T12222 |
T12220 |
advmod |
Figure,detected |
R10536 |
T12223 |
T12222 |
nummod |
6E,Figure |
R10537 |
T12224 |
T12222 |
punct |
),Figure |
R10538 |
T12225 |
T12197 |
punct |
.,result |
R10539 |
T12226 |
T12228 |
nsubj |
We,examined |
R10540 |
T12227 |
T12228 |
advmod |
further,examined |
R10541 |
T12228 |
T12228 |
ROOT |
examined,examined |
R10542 |
T12229 |
T12233 |
mark |
whether,affect |
R10543 |
T12230 |
T12231 |
amod |
inhaled,FP |
R10544 |
T12231 |
T12233 |
nsubj |
FP,affect |
R10545 |
T12232 |
T12233 |
aux |
could,affect |
R10546 |
T12233 |
T12228 |
ccomp |
affect,examined |
R10547 |
T12234 |
T12235 |
amod |
cellular,localization |
R10548 |
T12235 |
T12233 |
dobj |
localization,affect |
R10549 |
T12236 |
T12235 |
prep |
of,localization |
R10550 |
T12237 |
T12236 |
pobj |
GATA-3,of |
R10551 |
T12238 |
T12235 |
prep |
in,localization |
R10552 |
T12239 |
T12242 |
amod |
peripheral,cells |
R10553 |
T12240 |
T12242 |
compound |
blood,cells |
R10554 |
T12241 |
T12242 |
compound |
T,cells |
R10555 |
T12242 |
T12238 |
pobj |
cells,in |
R10556 |
T12243 |
T12228 |
punct |
.,examined |
R10557 |
T12244 |
T12256 |
nsubj |
Treatment,increased |
R10558 |
T12245 |
T12244 |
prep |
with,Treatment |
R10559 |
T12246 |
T12247 |
amod |
inhaled,FP |
R10560 |
T12247 |
T12245 |
pobj |
FP,with |
R10561 |
T12248 |
T12247 |
punct |
(,FP |
R10562 |
T12249 |
T12250 |
nummod |
500,µg |
R10563 |
T12250 |
T12247 |
appos |
µg,FP |
R10564 |
T12251 |
T12244 |
punct |
),Treatment |
R10565 |
T12252 |
T12244 |
prep |
for,Treatment |
R10566 |
T12253 |
T12254 |
nummod |
2,h |
R10567 |
T12254 |
T12252 |
pobj |
h,for |
R10568 |
T12255 |
T12256 |
advmod |
significantly,increased |
R10569 |
T12256 |
T12256 |
ROOT |
increased,increased |
R10570 |
T12257 |
T12259 |
nmod |
GR,translocation |
R10571 |
T12258 |
T12259 |
amod |
nuclear,translocation |
R10572 |
T12259 |
T12256 |
dobj |
translocation,increased |
R10573 |
T12260 |
T12262 |
punct |
(,7A |
R10574 |
T12261 |
T12262 |
compound |
Figure,7A |
R10575 |
T12262 |
T12259 |
appos |
7A,translocation |
R10576 |
T12263 |
T12262 |
punct |
),7A |
R10577 |
T12264 |
T12256 |
cc |
and,increased |
R10578 |
T12265 |
T12266 |
advmod |
concomitantly,decreased |
R10579 |
T12266 |
T12256 |
conj |
decreased,increased |
R10580 |
T12267 |
T12268 |
det |
the,number |
R10581 |
T12268 |
T12266 |
dobj |
number,decreased |
R10582 |
T12269 |
T12268 |
prep |
of,number |
R10583 |
T12270 |
T12276 |
amod |
nuclear,cells |
R10584 |
T12271 |
T12276 |
amod |
GATA-3,cells |
R10585 |
T12272 |
T12276 |
amod |
immunoreactive,cells |
R10586 |
T12273 |
T12276 |
amod |
peripheral,cells |
R10587 |
T12274 |
T12276 |
compound |
blood,cells |
R10588 |
T12275 |
T12276 |
compound |
T,cells |
R10589 |
T12276 |
T12269 |
pobj |
cells,of |
R10590 |
T12277 |
T12276 |
punct |
(,cells |
R10591 |
T12278 |
T12279 |
nummod |
37,% |
R10592 |
T12279 |
T12276 |
appos |
%,cells |
R10593 |
T12280 |
T12290 |
nummod |
±,p |
R10594 |
T12281 |
T12282 |
nummod |
4.2,% |
R10595 |
T12282 |
T12280 |
quantmod |
%,± |
R10596 |
T12283 |
T12280 |
cc |
versus,± |
R10597 |
T12284 |
T12285 |
nummod |
58.2,% |
R10598 |
T12285 |
T12290 |
dep |
%,p |
R10599 |
T12286 |
T12288 |
nummod |
±,% |
R10600 |
T12287 |
T12288 |
nummod |
4.95,% |
R10601 |
T12288 |
T12285 |
appos |
%,% |
R10602 |
T12289 |
T12290 |
punct |
",",p |
R10603 |
T12290 |
T12276 |
parataxis |
p,cells |
R10604 |
T12291 |
T12292 |
punct |
=,0.016 |
R10605 |
T12292 |
T12290 |
prep |
0.016,p |
R10606 |
T12293 |
T12303 |
punct |
",",compared |
R10607 |
T12294 |
T12303 |
nsubj |
W,compared |
R10608 |
T12295 |
T12294 |
punct |
=,W |
R10609 |
T12296 |
T12294 |
appos |
28.0,W |
R10610 |
T12297 |
T12294 |
punct |
",",W |
R10611 |
T12298 |
T12301 |
poss |
Wilcoxon,test |
R10612 |
T12299 |
T12298 |
case |
's,Wilcoxon |
R10613 |
T12300 |
T12301 |
compound |
rank,test |
R10614 |
T12301 |
T12294 |
appos |
test,W |
R10615 |
T12302 |
T12294 |
punct |
),W |
R10616 |
T12303 |
T12256 |
prep |
compared,increased |
R10617 |
T12304 |
T12303 |
prep |
with,compared |
R10618 |
T12305 |
T12304 |
pobj |
placebo,with |
R10619 |
T12306 |
T12307 |
mark |
as,measured |
R10620 |
T12307 |
T12303 |
advcl |
measured,compared |
R10621 |
T12308 |
T12307 |
agent |
by,measured |
R10622 |
T12309 |
T12308 |
pobj |
immunocytochemistry,by |
R10623 |
T12310 |
T12312 |
punct |
(,7A |
R10624 |
T12311 |
T12312 |
compound |
Figure,7A |
R10625 |
T12312 |
T12309 |
appos |
7A,immunocytochemistry |
R10626 |
T12313 |
T12312 |
cc |
and,7A |
R10627 |
T12314 |
T12312 |
conj |
7B,7A |
R10628 |
T12315 |
T12312 |
punct |
),7A |
R10629 |
T12316 |
T12303 |
punct |
.,compared |
R10630 |
T12317 |
T12319 |
nsubjpass |
This,confirmed |
R10631 |
T12318 |
T12319 |
auxpass |
was,confirmed |
R10632 |
T12319 |
T12319 |
ROOT |
confirmed,confirmed |
R10633 |
T12320 |
T12319 |
agent |
by,confirmed |
R10634 |
T12321 |
T12322 |
amod |
Western,blotting |
R10635 |
T12322 |
T12320 |
pobj |
blotting,by |
R10636 |
T12323 |
T12322 |
punct |
",",blotting |
R10637 |
T12324 |
T12326 |
nsubj |
which,indicated |
R10638 |
T12325 |
T12326 |
advmod |
also,indicated |
R10639 |
T12326 |
T12319 |
ccomp |
indicated,confirmed |
R10640 |
T12327 |
T12330 |
mark |
that,was |
R10641 |
T12328 |
T12329 |
det |
this,effect |
R10642 |
T12329 |
T12330 |
nsubj |
effect,was |
R10643 |
T12330 |
T12326 |
ccomp |
was,indicated |
R10644 |
T12331 |
T12332 |
preconj |
both,time |
R10645 |
T12332 |
T12330 |
attr |
time,was |
R10646 |
T12333 |
T12332 |
punct |
-,time |
R10647 |
T12334 |
T12332 |
cc |
and,time |
R10648 |
T12335 |
T12332 |
conj |
dose-dependent,time |
R10649 |
T12336 |
T12338 |
punct |
(,7C |
R10650 |
T12337 |
T12338 |
compound |
Figure,7C |
R10651 |
T12338 |
T12335 |
appos |
7C,dose-dependent |
R10652 |
T12339 |
T12338 |
cc |
and,7C |
R10653 |
T12340 |
T12338 |
conj |
7D,7C |
R10654 |
T12341 |
T12338 |
punct |
),7C |
R10655 |
T12342 |
T12319 |
punct |
.,confirmed |
R10656 |
T12343 |
T12345 |
advmod |
Thus,inhaled |
R10657 |
T12344 |
T12345 |
punct |
",",inhaled |
R10658 |
T12345 |
T12345 |
ROOT |
inhaled,inhaled |
R10659 |
T12346 |
T12345 |
dobj |
FP,inhaled |
R10660 |
T12347 |
T12346 |
punct |
(,FP |
R10661 |
T12348 |
T12349 |
nummod |
500,µg |
R10662 |
T12349 |
T12346 |
appos |
µg,FP |
R10663 |
T12350 |
T12346 |
punct |
),FP |
R10664 |
T12351 |
T12345 |
conj |
induced,inhaled |
R10665 |
T12352 |
T12353 |
amod |
significant,loss |
R10666 |
T12353 |
T12351 |
dobj |
loss,induced |
R10667 |
T12354 |
T12351 |
prep |
in,induced |
R10668 |
T12355 |
T12356 |
amod |
nuclear,GATA-3 |
R10669 |
T12356 |
T12354 |
pobj |
GATA-3,in |
R10670 |
T12357 |
T12351 |
prep |
at,induced |
R10671 |
T12358 |
T12359 |
nummod |
2,h |
R10672 |
T12359 |
T12357 |
pobj |
h,at |
R10673 |
T12360 |
T12366 |
punct |
(,] |
R10674 |
T12361 |
T12366 |
amod |
median,] |
R10675 |
T12362 |
T12366 |
compound |
[,] |
R10676 |
T12363 |
T12364 |
nummod |
95,% |
R10677 |
T12364 |
T12366 |
compound |
%,] |
R10678 |
T12365 |
T12366 |
compound |
CI,] |
R10679 |
T12366 |
T12381 |
meta |
],< |
R10680 |
T12367 |
T12366 |
punct |
",",] |
R10681 |
T12368 |
T12370 |
compound |
0.40,0.27 |
R10682 |
T12369 |
T12370 |
compound |
[,0.27 |
R10683 |
T12370 |
T12366 |
appos |
0.27,] |
R10684 |
T12371 |
T12372 |
nummod |
0.53,] |
R10685 |
T12372 |
T12366 |
conj |
],] |
R10686 |
T12373 |
T12372 |
cc |
versus,] |
R10687 |
T12374 |
T12376 |
compound |
0.14,0.11 |
R10688 |
T12375 |
T12376 |
compound |
[,0.11 |
R10689 |
T12376 |
T12366 |
appos |
0.11,] |
R10690 |
T12377 |
T12378 |
nummod |
0.19,] |
R10691 |
T12378 |
T12366 |
appos |
],] |
R10692 |
T12379 |
T12378 |
punct |
",",] |
R10693 |
T12380 |
T12381 |
compound |
p,< |
R10694 |
T12381 |
T12351 |
npadvmod |
<,induced |
R10695 |
T12382 |
T12381 |
nummod |
0.05,< |
R10696 |
T12383 |
T12381 |
punct |
",",< |
R10697 |
T12384 |
T12400 |
nmod |
W,levels |
R10698 |
T12385 |
T12384 |
punct |
=,W |
R10699 |
T12386 |
T12384 |
appos |
21.00,W |
R10700 |
T12387 |
T12384 |
punct |
",",W |
R10701 |
T12388 |
T12391 |
poss |
Wilcoxon,test |
R10702 |
T12389 |
T12388 |
case |
's,Wilcoxon |
R10703 |
T12390 |
T12391 |
compound |
rank,test |
R10704 |
T12391 |
T12384 |
appos |
test,W |
R10705 |
T12392 |
T12384 |
punct |
),W |
R10706 |
T12393 |
T12395 |
punct |
(,7C |
R10707 |
T12394 |
T12395 |
compound |
Figure,7C |
R10708 |
T12395 |
T12384 |
appos |
7C,W |
R10709 |
T12396 |
T12395 |
punct |
),7C |
R10710 |
T12397 |
T12384 |
cc |
and,W |
R10711 |
T12398 |
T12400 |
amod |
cytoplasmic,levels |
R10712 |
T12399 |
T12400 |
compound |
GATA-3,levels |
R10713 |
T12400 |
T12402 |
nsubjpass |
levels,enhanced |
R10714 |
T12401 |
T12402 |
auxpass |
were,enhanced |
R10715 |
T12402 |
T12351 |
conj |
enhanced,induced |
R10716 |
T12403 |
T12402 |
agent |
by,enhanced |
R10717 |
T12404 |
T12405 |
amod |
inhaled,FP |
R10718 |
T12405 |
T12403 |
pobj |
FP,by |
R10719 |
T12406 |
T12402 |
prep |
in,enhanced |
R10720 |
T12407 |
T12409 |
det |
a,manner |
R10721 |
T12408 |
T12409 |
amod |
dose-dependent,manner |
R10722 |
T12409 |
T12406 |
pobj |
manner,in |
R10723 |
T12410 |
T12416 |
punct |
(,] |
R10724 |
T12411 |
T12416 |
amod |
median,] |
R10725 |
T12412 |
T12416 |
compound |
[,] |
R10726 |
T12413 |
T12414 |
nummod |
95,% |
R10727 |
T12414 |
T12416 |
compound |
%,] |
R10728 |
T12415 |
T12416 |
compound |
CI,] |
R10729 |
T12416 |
T12409 |
appos |
],manner |
R10730 |
T12417 |
T12416 |
punct |
",",] |
R10731 |
T12418 |
T12420 |
nummod |
0.0032,0.0026 |
R10732 |
T12419 |
T12420 |
compound |
[,0.0026 |
R10733 |
T12420 |
T12416 |
appos |
0.0026,] |
R10734 |
T12421 |
T12422 |
nummod |
0.0039,] |
R10735 |
T12422 |
T12416 |
conj |
],] |
R10736 |
T12423 |
T12422 |
cc |
versus,] |
R10737 |
T12424 |
T12426 |
compound |
0.658,0.592 |
R10738 |
T12425 |
T12426 |
compound |
[,0.592 |
R10739 |
T12426 |
T12416 |
appos |
0.592,] |
R10740 |
T12427 |
T12428 |
nummod |
0.720,] |
R10741 |
T12428 |
T12416 |
appos |
],] |
R10742 |
T12429 |
T12428 |
punct |
",",] |
R10743 |
T12430 |
T12431 |
compound |
p,< |
R10744 |
T12431 |
T12432 |
compound |
<,0.05 |
R10745 |
T12432 |
T12428 |
appos |
0.05,] |
R10746 |
T12433 |
T12428 |
punct |
",",] |
R10747 |
T12434 |
T12428 |
amod |
W,] |
R10748 |
T12435 |
T12416 |
punct |
=,] |
R10749 |
T12436 |
T12416 |
punct |
−,] |
R10750 |
T12437 |
T12416 |
appos |
21.00,] |
R10751 |
T12438 |
T12416 |
punct |
",",] |
R10752 |
T12439 |
T12442 |
poss |
Wilcoxon,test |
R10753 |
T12440 |
T12439 |
case |
's,Wilcoxon |
R10754 |
T12441 |
T12442 |
compound |
rank,test |
R10755 |
T12442 |
T12416 |
appos |
test,] |
R10756 |
T12443 |
T12416 |
punct |
),] |
R10757 |
T12444 |
T12446 |
punct |
(,7D |
R10758 |
T12445 |
T12446 |
compound |
Figure,7D |
R10759 |
T12446 |
T12416 |
appos |
7D,] |
R10760 |
T12447 |
T12416 |
punct |
),] |
R10761 |
T12448 |
T12345 |
punct |
.,inhaled |
R10762 |
T12449 |
T12457 |
prep |
In,inhibited |
R10763 |
T12450 |
T12449 |
pobj |
addition,In |
R10764 |
T12451 |
T12457 |
punct |
",",inhibited |
R10765 |
T12452 |
T12457 |
nsubj |
FP,inhibited |
R10766 |
T12453 |
T12455 |
punct |
(,µg |
R10767 |
T12454 |
T12455 |
nummod |
500,µg |
R10768 |
T12455 |
T12452 |
appos |
µg,FP |
R10769 |
T12456 |
T12455 |
punct |
),µg |
R10770 |
T12457 |
T12457 |
ROOT |
inhibited,inhibited |
R10771 |
T12458 |
T12460 |
nummod |
p38,phosphorylation |
R10772 |
T12459 |
T12460 |
compound |
MAPK,phosphorylation |
R10773 |
T12460 |
T12457 |
dobj |
phosphorylation,inhibited |
R10774 |
T12461 |
T12460 |
prep |
in,phosphorylation |
R10775 |
T12462 |
T12464 |
amod |
primary,cells |
R10776 |
T12463 |
T12464 |
compound |
T,cells |
R10777 |
T12464 |
T12461 |
pobj |
cells,in |
R10778 |
T12465 |
T12457 |
prep |
in,inhibited |
R10779 |
T12466 |
T12465 |
pobj |
vivo,in |
R10780 |
T12467 |
T12457 |
prep |
at,inhibited |
R10781 |
T12468 |
T12469 |
nummod |
2,h |
R10782 |
T12469 |
T12467 |
pobj |
h,at |
R10783 |
T12470 |
T12469 |
prep |
in,h |
R10784 |
T12471 |
T12470 |
pobj |
samples,in |
R10785 |
T12472 |
T12471 |
prep |
from,samples |
R10786 |
T12473 |
T12474 |
nummod |
two,patients |
R10787 |
T12474 |
T12472 |
pobj |
patients,from |
R10788 |
T12475 |
T12474 |
punct |
(,patients |
R10789 |
T12476 |
T12474 |
appos |
Figure,patients |
R10790 |
T12477 |
T12476 |
nummod |
7E,Figure |
R10791 |
T12478 |
T12474 |
punct |
),patients |
R10792 |
T12479 |
T12457 |
punct |
.,inhibited |
R10793 |
T12480 |
T12485 |
advcl |
Taken,suggest |
R10794 |
T12481 |
T12480 |
advmod |
together,Taken |
R10795 |
T12482 |
T12485 |
punct |
",",suggest |
R10796 |
T12483 |
T12484 |
poss |
our,data |
R10797 |
T12484 |
T12485 |
nsubj |
data,suggest |
R10798 |
T12485 |
T12485 |
ROOT |
suggest,suggest |
R10799 |
T12486 |
T12487 |
mark |
that,inhaled |
R10800 |
T12487 |
T12485 |
ccomp |
inhaled,suggest |
R10801 |
T12488 |
T12489 |
nsubj |
FP,reduces |
R10802 |
T12489 |
T12487 |
pcomp |
reduces,inhaled |
R10803 |
T12490 |
T12491 |
amod |
nuclear,localization |
R10804 |
T12491 |
T12489 |
dobj |
localization,reduces |
R10805 |
T12492 |
T12491 |
prep |
of,localization |
R10806 |
T12493 |
T12492 |
pobj |
GATA-3,of |
R10807 |
T12494 |
T12491 |
prep |
in,localization |
R10808 |
T12495 |
T12494 |
pobj |
vivo,in |
R10809 |
T12496 |
T12489 |
prep |
by,reduces |
R10810 |
T12497 |
T12498 |
advmod |
acutely,inhibiting |
R10811 |
T12498 |
T12496 |
pcomp |
inhibiting,by |
R10812 |
T12499 |
T12498 |
dobj |
phospho-GATA-3,inhibiting |
R10813 |
T12500 |
T12501 |
compound |
importin,association |
R10814 |
T12501 |
T12498 |
npadvmod |
association,inhibiting |
R10815 |
T12502 |
T12485 |
punct |
.,suggest |
R10816 |
T12503 |
T12504 |
det |
This,effect |
R10817 |
T12504 |
T12506 |
nsubj |
effect,be |
R10818 |
T12505 |
T12506 |
aux |
may,be |
R10819 |
T12506 |
T12506 |
ROOT |
be,be |
R10820 |
T12507 |
T12506 |
acomp |
direct,be |
R10821 |
T12508 |
T12507 |
punct |
",",direct |
R10822 |
T12509 |
T12506 |
prep |
through,be |
R10823 |
T12510 |
T12509 |
pobj |
competition,through |
R10824 |
T12511 |
T12510 |
prep |
for,competition |
R10825 |
T12512 |
T12515 |
amod |
importin-α,molecules |
R10826 |
T12513 |
T12512 |
cc |
or,importin-α |
R10827 |
T12514 |
T12512 |
conj |
associated,importin-α |
R10828 |
T12515 |
T12511 |
pobj |
molecules,for |
R10829 |
T12516 |
T12515 |
punct |
",",molecules |
R10830 |
T12517 |
T12510 |
cc |
or,competition |
R10831 |
T12518 |
T12510 |
conj |
secondary,competition |
R10832 |
T12519 |
T12518 |
prep |
to,secondary |
R10833 |
T12520 |
T12521 |
det |
an,effect |
R10834 |
T12521 |
T12519 |
pobj |
effect,to |
R10835 |
T12522 |
T12521 |
prep |
on,effect |
R10836 |
T12523 |
T12526 |
nummod |
p38,phosphorylation |
R10837 |
T12524 |
T12526 |
nmod |
MAPK-mediated,phosphorylation |
R10838 |
T12525 |
T12526 |
amod |
GATA-3,phosphorylation |
R10839 |
T12526 |
T12522 |
pobj |
phosphorylation,on |
R10840 |
T12527 |
T12506 |
prep |
via,be |
R10841 |
T12528 |
T12529 |
amod |
rapid,induction |
R10842 |
T12529 |
T12527 |
pobj |
induction,via |
R10843 |
T12530 |
T12529 |
prep |
of,induction |
R10844 |
T12531 |
T12530 |
pobj |
MKP-1,of |
R10845 |
T12532 |
T12506 |
punct |
.,be |
R10846 |
T12533 |
T12534 |
det |
The,combination |
R10847 |
T12534 |
T12541 |
nsubj |
combination,result |
R10848 |
T12535 |
T12534 |
prep |
of,combination |
R10849 |
T12536 |
T12539 |
det |
these,effects |
R10850 |
T12537 |
T12539 |
nummod |
two,effects |
R10851 |
T12538 |
T12539 |
amod |
interacting,effects |
R10852 |
T12539 |
T12535 |
pobj |
effects,of |
R10853 |
T12540 |
T12541 |
aux |
can,result |
R10854 |
T12541 |
T12541 |
ROOT |
result,result |
R10855 |
T12542 |
T12541 |
prep |
in,result |
R10856 |
T12543 |
T12544 |
amod |
complete,suppression |
R10857 |
T12544 |
T12542 |
pobj |
suppression,in |
R10858 |
T12545 |
T12544 |
prep |
of,suppression |
R10859 |
T12546 |
T12554 |
amod |
GATA-3,expression |
R10860 |
T12547 |
T12548 |
amod |
nuclear,import |
R10861 |
T12548 |
T12554 |
nmod |
import,expression |
R10862 |
T12549 |
T12548 |
cc |
and,import |
R10863 |
T12550 |
T12554 |
advmod |
thus,expression |
R10864 |
T12551 |
T12554 |
amod |
Th2,expression |
R10865 |
T12552 |
T12554 |
amod |
cytokine,expression |
R10866 |
T12553 |
T12554 |
compound |
gene,expression |
R10867 |
T12554 |
T12545 |
pobj |
expression,of |
R10868 |
T12555 |
T12541 |
punct |
.,result |
R12321 |
T14309 |
T14312 |
advmod |
Here,demonstrated |
R12322 |
T14310 |
T14312 |
nsubj |
we,demonstrated |
R12323 |
T14311 |
T14312 |
aux |
have,demonstrated |
R12324 |
T14312 |
T14312 |
ROOT |
demonstrated,demonstrated |
R12325 |
T14313 |
T14312 |
punct |
",",demonstrated |
R12326 |
T14314 |
T14312 |
prep |
to,demonstrated |
R12327 |
T14315 |
T14316 |
poss |
our,knowledge |
R12328 |
T14316 |
T14314 |
pobj |
knowledge,to |
R12329 |
T14317 |
T14316 |
prep |
for,knowledge |
R12330 |
T14318 |
T14320 |
det |
the,time |
R12331 |
T14319 |
T14320 |
amod |
first,time |
R12332 |
T14320 |
T14317 |
pobj |
time,for |
R12333 |
T14321 |
T14312 |
punct |
",",demonstrated |
R12334 |
T14322 |
T14325 |
mark |
that,inhibit |
R12335 |
T14323 |
T14325 |
nsubj |
corticosteroids,inhibit |
R12336 |
T14324 |
T14325 |
aux |
may,inhibit |
R12337 |
T14325 |
T14312 |
ccomp |
inhibit,demonstrated |
R12338 |
T14326 |
T14327 |
compound |
GATA-3,function |
R12339 |
T14327 |
T14325 |
dobj |
function,inhibit |
R12340 |
T14328 |
T14325 |
cc |
and,inhibit |
R12341 |
T14329 |
T14331 |
advmod |
therefore,transcription |
R12342 |
T14330 |
T14331 |
det |
the,transcription |
R12343 |
T14331 |
T14325 |
conj |
transcription,inhibit |
R12344 |
T14332 |
T14331 |
prep |
of,transcription |
R12345 |
T14333 |
T14334 |
amod |
Th2,genes |
R12346 |
T14334 |
T14332 |
pobj |
genes,of |
R12347 |
T14335 |
T14331 |
prep |
via,transcription |
R12348 |
T14336 |
T14341 |
nummod |
two,mechanisms |
R12349 |
T14337 |
T14341 |
amod |
distinct,mechanisms |
R12350 |
T14338 |
T14337 |
cc |
but,distinct |
R12351 |
T14339 |
T14337 |
conj |
interacting,distinct |
R12352 |
T14340 |
T14341 |
amod |
molecular,mechanisms |
R12353 |
T14341 |
T14335 |
pobj |
mechanisms,via |
R12354 |
T14342 |
T14312 |
punct |
.,demonstrated |
R12355 |
T14343 |
T14347 |
advmod |
Firstly,appears |
R12356 |
T14344 |
T14347 |
punct |
",",appears |
R12357 |
T14345 |
T14346 |
compound |
corticosteroid-activated,GR |
R12358 |
T14346 |
T14347 |
nsubj |
GR,appears |
R12359 |
T14347 |
T14347 |
ROOT |
appears,appears |
R12360 |
T14348 |
T14349 |
aux |
to,compete |
R12361 |
T14349 |
T14347 |
xcomp |
compete,appears |
R12362 |
T14350 |
T14349 |
prep |
with,compete |
R12363 |
T14351 |
T14352 |
amod |
activated,GATA-3 |
R12364 |
T14352 |
T14350 |
pobj |
GATA-3,with |
R12365 |
T14353 |
T14349 |
prep |
for,compete |
R12366 |
T14354 |
T14355 |
amod |
nuclear,import |
R12367 |
T14355 |
T14353 |
pobj |
import,for |
R12368 |
T14356 |
T14349 |
prep |
via,compete |
R12369 |
T14357 |
T14356 |
pobj |
importin-α,via |
R12370 |
T14358 |
T14357 |
punct |
",",importin-α |
R12371 |
T14359 |
T14361 |
nsubjpass |
which,required |
R12372 |
T14360 |
T14361 |
auxpass |
is,required |
R12373 |
T14361 |
T14349 |
advcl |
required,compete |
R12374 |
T14362 |
T14361 |
prep |
for,required |
R12375 |
T14363 |
T14365 |
det |
the,transport |
R12376 |
T14364 |
T14365 |
amod |
nuclear,transport |
R12377 |
T14365 |
T14362 |
pobj |
transport,for |
R12378 |
T14366 |
T14365 |
prep |
of,transport |
R12379 |
T14367 |
T14368 |
preconj |
both,GATA-3 |
R12380 |
T14368 |
T14366 |
pobj |
GATA-3,of |
R12381 |
T14369 |
T14368 |
cc |
and,GATA-3 |
R12382 |
T14370 |
T14368 |
conj |
GR,GATA-3 |
R12383 |
T14371 |
T14347 |
punct |
.,appears |
R12384 |
T14372 |
T14378 |
advmod |
Secondly,increase |
R12385 |
T14373 |
T14378 |
punct |
",",increase |
R12386 |
T14374 |
T14378 |
nsubj |
corticosteroids,increase |
R12387 |
T14375 |
T14374 |
prep |
at,corticosteroids |
R12388 |
T14376 |
T14377 |
amod |
higher,concentrations |
R12389 |
T14377 |
T14375 |
pobj |
concentrations,at |
R12390 |
T14378 |
T14378 |
ROOT |
increase,increase |
R12391 |
T14379 |
T14380 |
det |
the,expression |
R12392 |
T14380 |
T14378 |
dobj |
expression,increase |
R12393 |
T14381 |
T14380 |
prep |
of,expression |
R12394 |
T14382 |
T14381 |
pobj |
MKP-1,of |
R12395 |
T14383 |
T14382 |
punct |
",",MKP-1 |
R12396 |
T14384 |
T14386 |
det |
a,inhibitor |
R12397 |
T14385 |
T14386 |
amod |
potent,inhibitor |
R12398 |
T14386 |
T14382 |
appos |
inhibitor,MKP-1 |
R12399 |
T14387 |
T14386 |
prep |
of,inhibitor |
R12400 |
T14388 |
T14390 |
nummod |
p38,activity |
R12401 |
T14389 |
T14390 |
compound |
MAPK,activity |
R12402 |
T14390 |
T14387 |
pobj |
activity,of |
R12403 |
T14391 |
T14378 |
cc |
and,increase |
R12404 |
T14392 |
T14393 |
advmod |
thereby,prevent |
R12405 |
T14393 |
T14378 |
conj |
prevent,increase |
R12406 |
T14394 |
T14397 |
compound |
T,activation |
R12407 |
T14395 |
T14396 |
compound |
cell,receptor/co-receptor |
R12408 |
T14396 |
T14397 |
compound |
receptor/co-receptor,activation |
R12409 |
T14397 |
T14393 |
dobj |
activation,prevent |
R12410 |
T14398 |
T14397 |
prep |
of,activation |
R12411 |
T14399 |
T14400 |
nummod |
p38,MAPK |
R12412 |
T14400 |
T14398 |
pobj |
MAPK,of |
R12413 |
T14401 |
T14402 |
aux |
to,prevent |
R12414 |
T14402 |
T14393 |
advcl |
prevent,prevent |
R12415 |
T14403 |
T14404 |
det |
the,phosphorylation |
R12416 |
T14404 |
T14402 |
dobj |
phosphorylation,prevent |
R12417 |
T14405 |
T14404 |
prep |
of,phosphorylation |
R12418 |
T14406 |
T14405 |
pobj |
GATA-3,of |
R12419 |
T14407 |
T14408 |
nsubj |
that,is |
R12420 |
T14408 |
T14406 |
relcl |
is,GATA-3 |
R12421 |
T14409 |
T14408 |
acomp |
necessary,is |
R12422 |
T14410 |
T14409 |
prep |
for,necessary |
R12423 |
T14411 |
T14410 |
pobj |
interaction,for |
R12424 |
T14412 |
T14411 |
prep |
with,interaction |
R12425 |
T14413 |
T14412 |
pobj |
importin-α,with |
R12426 |
T14414 |
T14413 |
cc |
and,importin-α |
R12427 |
T14415 |
T14417 |
amod |
subsequent,import |
R12428 |
T14416 |
T14417 |
amod |
nuclear,import |
R12429 |
T14417 |
T14413 |
conj |
import,importin-α |
R12430 |
T14418 |
T14378 |
punct |
.,increase |
R12431 |
T14419 |
T14422 |
nsubj |
We,shown |
R12432 |
T14420 |
T14422 |
aux |
have,shown |
R12433 |
T14421 |
T14422 |
advmod |
previously,shown |
R12434 |
T14422 |
T14422 |
ROOT |
shown,shown |
R12435 |
T14423 |
T14433 |
mark |
that,involves |
R12436 |
T14424 |
T14433 |
nsubj |
translocation,involves |
R12437 |
T14425 |
T14424 |
prep |
of,translocation |
R12438 |
T14426 |
T14425 |
pobj |
GATA-3,of |
R12439 |
T14427 |
T14424 |
prep |
from,translocation |
R12440 |
T14428 |
T14429 |
det |
the,cytoplasm |
R12441 |
T14429 |
T14427 |
pobj |
cytoplasm,from |
R12442 |
T14430 |
T14424 |
prep |
to,translocation |
R12443 |
T14431 |
T14432 |
det |
the,nucleus |
R12444 |
T14432 |
T14430 |
pobj |
nucleus,to |
R12445 |
T14433 |
T14422 |
ccomp |
involves,shown |
R12446 |
T14434 |
T14437 |
det |
the,protein |
R12447 |
T14435 |
T14436 |
amod |
nuclear,transporter |
R12448 |
T14436 |
T14437 |
compound |
transporter,protein |
R12449 |
T14437 |
T14438 |
compound |
protein,importin-α |
R12450 |
T14438 |
T14433 |
dobj |
importin-α,involves |
R12451 |
T14439 |
T14438 |
punct |
",",importin-α |
R12452 |
T14440 |
T14441 |
nsubj |
which,interacts |
R12453 |
T14441 |
T14438 |
relcl |
interacts,importin-α |
R12454 |
T14442 |
T14441 |
prep |
with,interacts |
R12455 |
T14443 |
T14445 |
amod |
phosphorylated,[ |
R12456 |
T14444 |
T14445 |
compound |
GATA-3,[ |
R12457 |
T14445 |
T14442 |
pobj |
[,with |
R12458 |
T14446 |
T14447 |
nummod |
12,] |
R12459 |
T14447 |
T14445 |
appos |
],[ |
R12460 |
T14448 |
T14422 |
punct |
.,shown |
R12461 |
T14449 |
T14453 |
nsubj |
We,reported |
R12462 |
T14450 |
T14453 |
aux |
have,reported |
R12463 |
T14451 |
T14453 |
advmod |
also,reported |
R12464 |
T14452 |
T14453 |
advmod |
previously,reported |
R12465 |
T14453 |
T14453 |
ROOT |
reported,reported |
R12466 |
T14454 |
T14466 |
mark |
that,stimulated |
R12467 |
T14455 |
T14456 |
amod |
GATA-3,knockdown |
R12468 |
T14456 |
T14466 |
nsubj |
knockdown,stimulated |
R12469 |
T14457 |
T14456 |
acl |
using,knockdown |
R12470 |
T14458 |
T14459 |
compound |
siRNA,results |
R12471 |
T14459 |
T14457 |
dobj |
results,using |
R12472 |
T14460 |
T14459 |
prep |
in,results |
R12473 |
T14461 |
T14460 |
pobj |
suppression,in |
R12474 |
T14462 |
T14461 |
prep |
of,suppression |
R12475 |
T14463 |
T14464 |
compound |
anti-CD3,/ |
R12476 |
T14464 |
T14465 |
compound |
/,CD28 |
R12477 |
T14465 |
T14462 |
pobj |
CD28,of |
R12478 |
T14466 |
T14453 |
ccomp |
stimulated,reported |
R12479 |
T14467 |
T14469 |
compound |
IL-4,IL-5 |
R12480 |
T14468 |
T14469 |
compound |
/,IL-5 |
R12481 |
T14469 |
T14470 |
compound |
IL-5,mRNA |
R12482 |
T14470 |
T14471 |
compound |
mRNA,induction |
R12483 |
T14471 |
T14466 |
dobj |
induction,stimulated |
R12484 |
T14472 |
T14466 |
punct |
",",stimulated |
R12485 |
T14473 |
T14474 |
advmod |
thus,implicating |
R12486 |
T14474 |
T14466 |
prep |
implicating,stimulated |
R12487 |
T14475 |
T14477 |
det |
an,role |
R12488 |
T14476 |
T14477 |
amod |
essential,role |
R12489 |
T14477 |
T14474 |
dobj |
role,implicating |
R12490 |
T14478 |
T14477 |
prep |
for,role |
R12491 |
T14479 |
T14478 |
pobj |
GATA-3,for |
R12492 |
T14480 |
T14477 |
prep |
in,role |
R12493 |
T14481 |
T14482 |
det |
the,transcription |
R12494 |
T14482 |
T14480 |
pobj |
transcription,in |
R12495 |
T14483 |
T14482 |
prep |
of,transcription |
R12496 |
T14484 |
T14485 |
det |
these,genes |
R12497 |
T14485 |
T14483 |
pobj |
genes,of |
R12498 |
T14486 |
T14488 |
nmod |
[,] |
R12499 |
T14487 |
T14488 |
nummod |
12,] |
R12500 |
T14488 |
T14482 |
appos |
],transcription |
R12501 |
T14489 |
T14453 |
punct |
.,reported |
R12502 |
T14490 |
T14492 |
nsubj |
We,confirm |
R12503 |
T14491 |
T14492 |
advmod |
now,confirm |
R12504 |
T14492 |
T14492 |
ROOT |
confirm,confirm |
R12505 |
T14493 |
T14492 |
punct |
",",confirm |
R12506 |
T14494 |
T14492 |
prep |
in,confirm |
R12507 |
T14495 |
T14497 |
amod |
human,cells |
R12508 |
T14496 |
T14497 |
compound |
T,cells |
R12509 |
T14497 |
T14494 |
pobj |
cells,in |
R12510 |
T14498 |
T14492 |
punct |
",",confirm |
R12511 |
T14499 |
T14502 |
mark |
that,uses |
R12512 |
T14500 |
T14502 |
nsubj |
GR,uses |
R12513 |
T14501 |
T14502 |
advmod |
also,uses |
R12514 |
T14502 |
T14492 |
ccomp |
uses,confirm |
R12515 |
T14503 |
T14507 |
det |
the,mechanism |
R12516 |
T14504 |
T14507 |
amod |
same,mechanism |
R12517 |
T14505 |
T14507 |
amod |
nuclear,mechanism |
R12518 |
T14506 |
T14507 |
compound |
import,mechanism |
R12519 |
T14507 |
T14502 |
dobj |
mechanism,uses |
R12520 |
T14508 |
T14502 |
prep |
as,uses |
R12521 |
T14509 |
T14510 |
compound |
GATA-3,[ |
R12522 |
T14510 |
T14508 |
pobj |
[,as |
R12523 |
T14511 |
T14512 |
nummod |
22,] |
R12524 |
T14512 |
T14510 |
appos |
],[ |
R12525 |
T14513 |
T14492 |
punct |
.,confirm |
R12526 |
T14514 |
T14516 |
nsubj |
We,propose |
R12527 |
T14515 |
T14516 |
advmod |
therefore,propose |
R12528 |
T14516 |
T14516 |
ROOT |
propose,propose |
R12529 |
T14517 |
T14519 |
mark |
that,is |
R12530 |
T14518 |
T14519 |
expl |
there,is |
R12531 |
T14519 |
T14516 |
ccomp |
is,propose |
R12532 |
T14520 |
T14519 |
attr |
competition,is |
R12533 |
T14521 |
T14520 |
prep |
between,competition |
R12534 |
T14522 |
T14523 |
compound |
ligand-activated,GR |
R12535 |
T14523 |
T14521 |
pobj |
GR,between |
R12536 |
T14524 |
T14523 |
cc |
and,GR |
R12537 |
T14525 |
T14523 |
conj |
phospho-GATA-3,GR |
R12538 |
T14526 |
T14520 |
prep |
for,competition |
R12539 |
T14527 |
T14528 |
amod |
nuclear,import |
R12540 |
T14528 |
T14526 |
pobj |
import,for |
R12541 |
T14529 |
T14516 |
punct |
.,propose |
R12542 |
T14530 |
T14534 |
advmod |
Furthermore,shown |
R12543 |
T14531 |
T14534 |
punct |
",",shown |
R12544 |
T14532 |
T14534 |
nsubj |
we,shown |
R12545 |
T14533 |
T14534 |
aux |
have,shown |
R12546 |
T14534 |
T14534 |
ROOT |
shown,shown |
R12547 |
T14535 |
T14537 |
mark |
that,is |
R12548 |
T14536 |
T14537 |
expl |
there,is |
R12549 |
T14537 |
T14534 |
ccomp |
is,shown |
R12550 |
T14538 |
T14539 |
amod |
preferential,binding |
R12551 |
T14539 |
T14537 |
attr |
binding,is |
R12552 |
T14540 |
T14539 |
prep |
of,binding |
R12553 |
T14541 |
T14540 |
pobj |
importin-α,of |
R12554 |
T14542 |
T14543 |
aux |
to,activated |
R12555 |
T14543 |
T14534 |
xcomp |
activated,shown |
R12556 |
T14544 |
T14543 |
dobj |
GR,activated |
R12557 |
T14545 |
T14543 |
prep |
over,activated |
R12558 |
T14546 |
T14545 |
pobj |
phospho-GATA-3,over |
R12559 |
T14547 |
T14534 |
punct |
",",shown |
R12560 |
T14548 |
T14553 |
mark |
so,reduce |
R12561 |
T14549 |
T14553 |
mark |
that,reduce |
R12562 |
T14550 |
T14553 |
nsubj |
corticosteroids,reduce |
R12563 |
T14551 |
T14553 |
aux |
would,reduce |
R12564 |
T14552 |
T14553 |
advmod |
preferentially,reduce |
R12565 |
T14553 |
T14534 |
advcl |
reduce,shown |
R12566 |
T14554 |
T14555 |
compound |
GATA-3,entry |
R12567 |
T14555 |
T14553 |
dobj |
entry,reduce |
R12568 |
T14556 |
T14553 |
cc |
and,reduce |
R12569 |
T14557 |
T14559 |
advmod |
thus,switch |
R12570 |
T14558 |
T14559 |
advmod |
rapidly,switch |
R12571 |
T14559 |
T14553 |
conj |
switch,reduce |
R12572 |
T14560 |
T14559 |
prt |
off,switch |
R12573 |
T14561 |
T14563 |
nummod |
Th2,transcription |
R12574 |
T14562 |
T14563 |
compound |
gene,transcription |
R12575 |
T14563 |
T14559 |
dobj |
transcription,switch |
R12576 |
T14564 |
T14559 |
prep |
without,switch |
R12577 |
T14565 |
T14566 |
det |
any,need |
R12578 |
T14566 |
T14564 |
pobj |
need,without |
R12579 |
T14567 |
T14566 |
prep |
for,need |
R12580 |
T14568 |
T14570 |
det |
any,steps |
R12581 |
T14569 |
T14570 |
amod |
intermediate,steps |
R12582 |
T14570 |
T14567 |
pobj |
steps,for |
R12583 |
T14571 |
T14534 |
punct |
.,shown |
R12584 |
T14572 |
T14575 |
advmod |
Furthermore,was |
R12585 |
T14573 |
T14575 |
punct |
",",was |
R12586 |
T14574 |
T14575 |
expl |
there,was |
R12587 |
T14575 |
T14575 |
ROOT |
was,was |
R12588 |
T14576 |
T14577 |
det |
some,degree |
R12589 |
T14577 |
T14575 |
attr |
degree,was |
R12590 |
T14578 |
T14577 |
prep |
of,degree |
R12591 |
T14579 |
T14578 |
pobj |
specificity,of |
R12592 |
T14580 |
T14577 |
prep |
for,degree |
R12593 |
T14581 |
T14580 |
pobj |
GATA-3,for |
R12594 |
T14582 |
T14577 |
punct |
",",degree |
R12595 |
T14583 |
T14594 |
mark |
as,affected |
R12596 |
T14584 |
T14585 |
amod |
nuclear,translocation |
R12597 |
T14585 |
T14583 |
pobj |
translocation,as |
R12598 |
T14586 |
T14585 |
prep |
of,translocation |
R12599 |
T14587 |
T14589 |
det |
the,subunit |
R12600 |
T14588 |
T14589 |
nummod |
p65,subunit |
R12601 |
T14589 |
T14586 |
pobj |
subunit,of |
R12602 |
T14590 |
T14589 |
prep |
of,subunit |
R12603 |
T14591 |
T14590 |
pobj |
NF-κB,of |
R12604 |
T14592 |
T14594 |
auxpass |
was,affected |
R12605 |
T14593 |
T14594 |
neg |
not,affected |
R12606 |
T14594 |
T14575 |
advcl |
affected,was |
R12607 |
T14595 |
T14594 |
agent |
by,affected |
R12608 |
T14596 |
T14597 |
amod |
corticosteroid,exposure |
R12609 |
T14597 |
T14595 |
pobj |
exposure,by |
R12610 |
T14598 |
T14575 |
punct |
.,was |
R12611 |
T14599 |
T14600 |
nsubj |
We,tested |
R12612 |
T14600 |
T14600 |
ROOT |
tested,tested |
R12613 |
T14601 |
T14603 |
det |
some,explanations |
R12614 |
T14602 |
T14603 |
amod |
alternative,explanations |
R12615 |
T14603 |
T14600 |
dobj |
explanations,tested |
R12616 |
T14604 |
T14603 |
prep |
for,explanations |
R12617 |
T14605 |
T14606 |
det |
this,effect |
R12618 |
T14606 |
T14604 |
pobj |
effect,for |
R12619 |
T14607 |
T14606 |
prep |
of,effect |
R12620 |
T14608 |
T14607 |
pobj |
FP,of |
R12621 |
T14609 |
T14606 |
prep |
on,effect |
R12622 |
T14610 |
T14612 |
nmod |
GATA-3,exclusion |
R12623 |
T14611 |
T14612 |
amod |
nuclear,exclusion |
R12624 |
T14612 |
T14609 |
pobj |
exclusion,on |
R12625 |
T14613 |
T14600 |
cc |
and,tested |
R12626 |
T14614 |
T14600 |
conj |
failed,tested |
R12627 |
T14615 |
T14616 |
aux |
to,show |
R12628 |
T14616 |
T14614 |
xcomp |
show,failed |
R12629 |
T14617 |
T14620 |
mark |
that,enhances |
R12630 |
T14618 |
T14620 |
nsubj |
FP,enhances |
R12631 |
T14619 |
T14620 |
preconj |
either,enhances |
R12632 |
T14620 |
T14616 |
ccomp |
enhances,show |
R12633 |
T14621 |
T14623 |
amod |
GATA-3,export |
R12634 |
T14622 |
T14623 |
amod |
nuclear,export |
R12635 |
T14623 |
T14620 |
dobj |
export,enhances |
R12636 |
T14624 |
T14620 |
advmod |
directly,enhances |
R12637 |
T14625 |
T14620 |
cc |
or,enhances |
R12638 |
T14626 |
T14620 |
conj |
induces,enhances |
R12639 |
T14627 |
T14628 |
amod |
GATA-3,degradation |
R12640 |
T14628 |
T14626 |
dobj |
degradation,induces |
R12641 |
T14629 |
T14600 |
punct |
.,tested |
R12642 |
T14630 |
T14631 |
det |
The,evidence |
R12643 |
T14631 |
T14638 |
nsubj |
evidence,does |
R12644 |
T14632 |
T14631 |
prep |
from,evidence |
R12645 |
T14633 |
T14638 |
det |
the,does |
R12646 |
T14634 |
T14638 |
prep |
in,does |
R12647 |
T14635 |
T14636 |
amod |
vitro,competition |
R12648 |
T14636 |
T14637 |
compound |
competition,assays |
R12649 |
T14637 |
T14634 |
pobj |
assays,in |
R12650 |
T14638 |
T14642 |
aux |
does,suggest |
R12651 |
T14639 |
T14642 |
punct |
",",suggest |
R12652 |
T14640 |
T14642 |
advmod |
however,suggest |
R12653 |
T14641 |
T14642 |
punct |
",",suggest |
R12654 |
T14642 |
T14642 |
ROOT |
suggest,suggest |
R12655 |
T14643 |
T14649 |
mark |
that,attenuate |
R12656 |
T14644 |
T14646 |
amod |
purified,GR |
R12657 |
T14645 |
T14646 |
amod |
activated,GR |
R12658 |
T14646 |
T14649 |
nsubj |
GR,attenuate |
R12659 |
T14647 |
T14649 |
aux |
can,attenuate |
R12660 |
T14648 |
T14649 |
advmod |
clearly,attenuate |
R12661 |
T14649 |
T14642 |
ccomp |
attenuate,suggest |
R12662 |
T14650 |
T14651 |
amod |
purified,phospho-GATA-3 |
R12663 |
T14651 |
T14649 |
dobj |
phospho-GATA-3,attenuate |
R12664 |
T14652 |
T14653 |
amod |
importin-α,association |
R12665 |
T14653 |
T14651 |
appos |
association,phospho-GATA-3 |
R12666 |
T14654 |
T14649 |
cc |
and,attenuate |
R12667 |
T14655 |
T14660 |
mark |
that,occur |
R12668 |
T14656 |
T14657 |
det |
the,converse |
R12669 |
T14657 |
T14660 |
nsubj |
converse,occur |
R12670 |
T14658 |
T14660 |
aux |
does,occur |
R12671 |
T14659 |
T14660 |
neg |
not,occur |
R12672 |
T14660 |
T14649 |
conj |
occur,attenuate |
R12673 |
T14661 |
T14642 |
punct |
.,suggest |
R12674 |
T14662 |
T14666 |
advmod |
Furthermore,shown |
R12675 |
T14663 |
T14666 |
punct |
",",shown |
R12676 |
T14664 |
T14666 |
nsubj |
we,shown |
R12677 |
T14665 |
T14666 |
aux |
have,shown |
R12678 |
T14666 |
T14666 |
ROOT |
shown,shown |
R12679 |
T14667 |
T14671 |
mark |
that,associate |
R12680 |
T14668 |
T14669 |
advmod |
only,phospho-GATA-3 |
R12681 |
T14669 |
T14671 |
nsubj |
phospho-GATA-3,associate |
R12682 |
T14670 |
T14671 |
aux |
can,associate |
R12683 |
T14671 |
T14666 |
ccomp |
associate,shown |
R12684 |
T14672 |
T14671 |
prep |
with,associate |
R12685 |
T14673 |
T14672 |
pobj |
importin-α,with |
R12686 |
T14674 |
T14666 |
punct |
.,shown |
R12687 |
T14675 |
T14676 |
det |
This,mechanism |
R12688 |
T14676 |
T14677 |
nsubj |
mechanism,is |
R12689 |
T14677 |
T14677 |
ROOT |
is,is |
R12690 |
T14678 |
T14677 |
acomp |
sensitive,is |
R12691 |
T14679 |
T14678 |
prep |
to,sensitive |
R12692 |
T14680 |
T14681 |
advmod |
very,low |
R12693 |
T14681 |
T14682 |
amod |
low,concentrations |
R12694 |
T14682 |
T14679 |
pobj |
concentrations,to |
R12695 |
T14683 |
T14682 |
prep |
of,concentrations |
R12696 |
T14684 |
T14683 |
pobj |
corticosteroid,of |
R12697 |
T14685 |
T14677 |
cc |
and,is |
R12698 |
T14686 |
T14687 |
aux |
would,be |
R12699 |
T14687 |
T14677 |
conj |
be,is |
R12700 |
T14688 |
T14687 |
acomp |
rapid,be |
R12701 |
T14689 |
T14688 |
prep |
in,rapid |
R12702 |
T14690 |
T14689 |
pobj |
onset,in |
R12703 |
T14691 |
T14698 |
mark |
as,required |
R12704 |
T14692 |
T14693 |
det |
no,changes |
R12705 |
T14693 |
T14698 |
nsubjpass |
changes,required |
R12706 |
T14694 |
T14693 |
prep |
in,changes |
R12707 |
T14695 |
T14696 |
compound |
protein,synthesis |
R12708 |
T14696 |
T14694 |
pobj |
synthesis,in |
R12709 |
T14697 |
T14698 |
auxpass |
are,required |
R12710 |
T14698 |
T14687 |
advcl |
required,be |
R12711 |
T14699 |
T14677 |
punct |
.,is |
R12712 |
T14700 |
T14702 |
det |
This,mechanism |
R12713 |
T14701 |
T14702 |
amod |
acute,mechanism |
R12714 |
T14702 |
T14705 |
nsubj |
mechanism,contribute |
R12715 |
T14703 |
T14705 |
aux |
may,contribute |
R12716 |
T14704 |
T14705 |
advmod |
also,contribute |
R12717 |
T14705 |
T14705 |
ROOT |
contribute,contribute |
R12718 |
T14706 |
T14705 |
prep |
to,contribute |
R12719 |
T14707 |
T14708 |
det |
the,reduction |
R12720 |
T14708 |
T14706 |
pobj |
reduction,to |
R12721 |
T14709 |
T14708 |
prep |
in,reduction |
R12722 |
T14710 |
T14712 |
amod |
GATA-3,import |
R12723 |
T14711 |
T14712 |
amod |
nuclear,import |
R12724 |
T14712 |
T14709 |
pobj |
import,in |
R12725 |
T14713 |
T14705 |
cc |
and,contribute |
R12726 |
T14714 |
T14715 |
aux |
may,play |
R12727 |
T14715 |
T14705 |
conj |
play,contribute |
R12728 |
T14716 |
T14718 |
det |
a,role |
R12729 |
T14717 |
T14718 |
amod |
major,role |
R12730 |
T14718 |
T14715 |
dobj |
role,play |
R12731 |
T14719 |
T14715 |
prep |
at,play |
R12732 |
T14720 |
T14722 |
amod |
low,concentrations |
R12733 |
T14721 |
T14722 |
amod |
corticosteroid,concentrations |
R12734 |
T14722 |
T14719 |
pobj |
concentrations,at |
R12735 |
T14723 |
T14719 |
cc |
and/or,at |
R12736 |
T14724 |
T14719 |
conj |
at,at |
R12737 |
T14725 |
T14726 |
amod |
early,time |
R12738 |
T14726 |
T14724 |
pobj |
time,at |
R12739 |
T14727 |
T14728 |
compound |
points,prior |
R12740 |
T14728 |
T14715 |
advmod |
prior,play |
R12741 |
T14729 |
T14728 |
prep |
to,prior |
R12742 |
T14730 |
T14731 |
compound |
MKP-1,induction |
R12743 |
T14731 |
T14729 |
pobj |
induction,to |
R12744 |
T14732 |
T14705 |
punct |
.,contribute |
R12745 |
T14733 |
T14735 |
nsubj |
Corticosteroids,modulate |
R12746 |
T14734 |
T14735 |
aux |
can,modulate |
R12747 |
T14735 |
T14735 |
ROOT |
modulate,modulate |
R12748 |
T14736 |
T14738 |
nummod |
p38,activity |
R12749 |
T14737 |
T14738 |
compound |
MAPK,activity |
R12750 |
T14738 |
T14735 |
dobj |
activity,modulate |
R12751 |
T14739 |
T14735 |
prep |
through,modulate |
R12752 |
T14740 |
T14741 |
det |
the,induction |
R12753 |
T14741 |
T14739 |
pobj |
induction,through |
R12754 |
T14742 |
T14741 |
prep |
of,induction |
R12755 |
T14743 |
T14742 |
pobj |
MKP-1,of |
R12756 |
T14744 |
T14743 |
punct |
",",MKP-1 |
R12757 |
T14745 |
T14748 |
det |
a,inhibitor |
R12758 |
T14746 |
T14748 |
amod |
potent,inhibitor |
R12759 |
T14747 |
T14748 |
amod |
endogenous,inhibitor |
R12760 |
T14748 |
T14743 |
appos |
inhibitor,MKP-1 |
R12761 |
T14749 |
T14748 |
prep |
of,inhibitor |
R12762 |
T14750 |
T14751 |
compound |
MAPK,function |
R12763 |
T14751 |
T14749 |
pobj |
function,of |
R12764 |
T14752 |
T14754 |
nmod |
[,] |
R12765 |
T14753 |
T14754 |
nummod |
38,] |
R12766 |
T14754 |
T14748 |
appos |
],inhibitor |
R12767 |
T14755 |
T14754 |
punct |
",",] |
R12768 |
T14756 |
T14758 |
nmod |
[,] |
R12769 |
T14757 |
T14758 |
nummod |
39,] |
R12770 |
T14758 |
T14754 |
appos |
],] |
R12771 |
T14759 |
T14735 |
punct |
.,modulate |
R12772 |
T14760 |
T14761 |
nsubj |
We,report |
R12773 |
T14761 |
T14761 |
ROOT |
report,report |
R12774 |
T14762 |
T14761 |
advmod |
here,report |
R12775 |
T14763 |
T14765 |
det |
a,induction |
R12776 |
T14764 |
T14765 |
amod |
rapid,induction |
R12777 |
T14765 |
T14761 |
dobj |
induction,report |
R12778 |
T14766 |
T14765 |
prep |
of,induction |
R12779 |
T14767 |
T14768 |
compound |
MKP-1,mRNA |
R12780 |
T14768 |
T14766 |
pobj |
mRNA,of |
R12781 |
T14769 |
T14765 |
prep |
following,induction |
R12782 |
T14770 |
T14769 |
pobj |
stimulation,following |
R12783 |
T14771 |
T14770 |
prep |
of,stimulation |
R12784 |
T14772 |
T14771 |
pobj |
cells,of |
R12785 |
T14773 |
T14772 |
prep |
with,cells |
R12786 |
T14774 |
T14775 |
advmod |
relatively,high |
R12787 |
T14775 |
T14776 |
amod |
high,concentrations |
R12788 |
T14776 |
T14773 |
pobj |
concentrations,with |
R12789 |
T14777 |
T14776 |
prep |
of,concentrations |
R12790 |
T14778 |
T14777 |
pobj |
FP,of |
R12791 |
T14779 |
T14761 |
punct |
.,report |
R12792 |
T14780 |
T14781 |
nsubj |
We,hypothesize |
R12793 |
T14781 |
T14781 |
ROOT |
hypothesize,hypothesize |
R12794 |
T14782 |
T14789 |
mark |
that,reduce |
R12795 |
T14783 |
T14785 |
det |
this,induction |
R12796 |
T14784 |
T14785 |
amod |
rapid,induction |
R12797 |
T14785 |
T14789 |
nsubj |
induction,reduce |
R12798 |
T14786 |
T14785 |
prep |
of,induction |
R12799 |
T14787 |
T14786 |
pobj |
MKP-1,of |
R12800 |
T14788 |
T14789 |
aux |
can,reduce |
R12801 |
T14789 |
T14781 |
ccomp |
reduce,hypothesize |
R12802 |
T14790 |
T14792 |
amod |
GATA-3,import |
R12803 |
T14791 |
T14792 |
amod |
nuclear,import |
R12804 |
T14792 |
T14789 |
dobj |
import,reduce |
R12805 |
T14793 |
T14789 |
prep |
by,reduce |
R12806 |
T14794 |
T14793 |
pcomp |
attenuating,by |
R12807 |
T14795 |
T14797 |
nummod |
p38,activity |
R12808 |
T14796 |
T14797 |
compound |
MAPK,activity |
R12809 |
T14797 |
T14794 |
dobj |
activity,attenuating |
R12810 |
T14798 |
T14797 |
cc |
and,activity |
R12811 |
T14799 |
T14801 |
amod |
subsequent,phosphorylation |
R12812 |
T14800 |
T14801 |
compound |
GATA-3,phosphorylation |
R12813 |
T14801 |
T14797 |
conj |
phosphorylation,activity |
R12814 |
T14802 |
T14789 |
punct |
",",reduce |
R12815 |
T14803 |
T14804 |
advmod |
thus,preventing |
R12816 |
T14804 |
T14789 |
advcl |
preventing,reduce |
R12817 |
T14805 |
T14806 |
amod |
nuclear,translocation |
R12818 |
T14806 |
T14804 |
dobj |
translocation,preventing |
R12819 |
T14807 |
T14781 |
punct |
.,hypothesize |
R12820 |
T14808 |
T14809 |
det |
The,location |
R12821 |
T14809 |
T14825 |
nsubj |
location,are |
R12822 |
T14810 |
T14809 |
prep |
of,location |
R12823 |
T14811 |
T14813 |
det |
the,residue |
R12824 |
T14812 |
T14813 |
compound |
serine,residue |
R12825 |
T14813 |
T14810 |
pobj |
residue,of |
R12826 |
T14814 |
T14813 |
punct |
(,residue |
R12827 |
T14815 |
T14813 |
appos |
s,residue |
R12828 |
T14816 |
T14813 |
punct |
),residue |
R12829 |
T14817 |
T14813 |
prep |
of,residue |
R12830 |
T14818 |
T14817 |
pobj |
GATA-3,of |
R12831 |
T14819 |
T14821 |
nsubjpass |
that,phosphorylated |
R12832 |
T14820 |
T14821 |
auxpass |
are,phosphorylated |
R12833 |
T14821 |
T14813 |
relcl |
phosphorylated,residue |
R12834 |
T14822 |
T14821 |
agent |
by,phosphorylated |
R12835 |
T14823 |
T14824 |
nummod |
p38,MAPK |
R12836 |
T14824 |
T14822 |
pobj |
MAPK,by |
R12837 |
T14825 |
T14825 |
ROOT |
are,are |
R12838 |
T14826 |
T14825 |
advmod |
currently,are |
R12839 |
T14827 |
T14825 |
acomp |
unknown,are |
R12840 |
T14828 |
T14825 |
punct |
",",are |
R12841 |
T14829 |
T14825 |
cc |
but,are |
R12842 |
T14830 |
T14832 |
det |
a,search |
R12843 |
T14831 |
T14832 |
compound |
bioinformatics,search |
R12844 |
T14832 |
T14839 |
nsubj |
search,indicates |
R12845 |
T14833 |
T14832 |
punct |
(,search |
R12846 |
T14834 |
T14835 |
compound |
Motif,Scanner |
R12847 |
T14835 |
T14832 |
appos |
Scanner,search |
R12848 |
T14836 |
T14835 |
punct |
",",Scanner |
R12849 |
T14837 |
T14835 |
appos |
http://scansite.mit.edu/motifscan_seq.phtml,Scanner |
R12850 |
T14838 |
T14835 |
punct |
),Scanner |
R12851 |
T14839 |
T14825 |
conj |
indicates,are |
R12852 |
T14840 |
T14841 |
advmod |
at,least |
R12853 |
T14841 |
T14842 |
advmod |
least,three |
R12854 |
T14842 |
T14847 |
nummod |
three,residues |
R12855 |
T14843 |
T14847 |
amod |
potential,residues |
R12856 |
T14844 |
T14847 |
nummod |
p38,residues |
R12857 |
T14845 |
T14847 |
amod |
MAPK-sensitive,residues |
R12858 |
T14846 |
T14847 |
compound |
serine,residues |
R12859 |
T14847 |
T14839 |
dobj |
residues,indicates |
R12860 |
T14848 |
T14839 |
punct |
.,indicates |
R12861 |
T14849 |
T14850 |
mark |
As,predicted |
R12862 |
T14850 |
T14871 |
advcl |
predicted,underlie |
R12863 |
T14851 |
T14850 |
prep |
from,predicted |
R12864 |
T14852 |
T14851 |
pobj |
these,from |
R12865 |
T14853 |
T14850 |
prep |
in,predicted |
R12866 |
T14854 |
T14855 |
compound |
vitro,data |
R12867 |
T14855 |
T14853 |
pobj |
data,in |
R12868 |
T14856 |
T14855 |
punct |
",",data |
R12869 |
T14857 |
T14871 |
nsubj |
impairment,underlie |
R12870 |
T14858 |
T14857 |
prep |
of,impairment |
R12871 |
T14859 |
T14861 |
amod |
GATA-3,import |
R12872 |
T14860 |
T14861 |
amod |
nuclear,import |
R12873 |
T14861 |
T14858 |
pobj |
import,of |
R12874 |
T14862 |
T14857 |
prep |
by,impairment |
R12875 |
T14863 |
T14862 |
pobj |
FP,by |
R12876 |
T14864 |
T14871 |
aux |
may,underlie |
R12877 |
T14865 |
T14871 |
punct |
",",underlie |
R12878 |
T14866 |
T14867 |
advmod |
at,least |
R12879 |
T14867 |
T14868 |
advmod |
least,in |
R12880 |
T14868 |
T14871 |
prep |
in,underlie |
R12881 |
T14869 |
T14868 |
pobj |
part,in |
R12882 |
T14870 |
T14871 |
punct |
",",underlie |
R12883 |
T14871 |
T14871 |
ROOT |
underlie,underlie |
R12884 |
T14872 |
T14873 |
det |
the,efficacy |
R12885 |
T14873 |
T14871 |
dobj |
efficacy,underlie |
R12886 |
T14874 |
T14873 |
prep |
of,efficacy |
R12887 |
T14875 |
T14874 |
pobj |
corticosteroids,of |
R12888 |
T14876 |
T14871 |
prep |
in,underlie |
R12889 |
T14877 |
T14876 |
pcomp |
suppressing,in |
R12890 |
T14878 |
T14879 |
amod |
allergic,inflammation |
R12891 |
T14879 |
T14877 |
dobj |
inflammation,suppressing |
R12892 |
T14880 |
T14871 |
punct |
.,underlie |
R12893 |
T14881 |
T14885 |
mark |
Although,assess |
R12894 |
T14882 |
T14885 |
nsubj |
we,assess |
R12895 |
T14883 |
T14885 |
aux |
did,assess |
R12896 |
T14884 |
T14885 |
neg |
not,assess |
R12897 |
T14885 |
T14911 |
advcl |
assess,have |
R12898 |
T14886 |
T14889 |
det |
the,effect |
R12899 |
T14887 |
T14889 |
amod |
acute,effect |
R12900 |
T14888 |
T14889 |
amod |
inhibitory,effect |
R12901 |
T14889 |
T14885 |
dobj |
effect,assess |
R12902 |
T14890 |
T14889 |
prep |
of,effect |
R12903 |
T14891 |
T14890 |
pobj |
FP,of |
R12904 |
T14892 |
T14889 |
prep |
on,effect |
R12905 |
T14893 |
T14894 |
det |
the,expression |
R12906 |
T14894 |
T14892 |
pobj |
expression,on |
R12907 |
T14895 |
T14894 |
prep |
of,expression |
R12908 |
T14896 |
T14897 |
compound |
IL-4,mRNA |
R12909 |
T14897 |
T14895 |
pobj |
mRNA,of |
R12910 |
T14898 |
T14889 |
prep |
in,effect |
R12911 |
T14899 |
T14898 |
pobj |
vivo,in |
R12912 |
T14900 |
T14899 |
punct |
",",vivo |
R12913 |
T14901 |
T14903 |
det |
a,inhalation |
R12914 |
T14902 |
T14903 |
amod |
single,inhalation |
R12915 |
T14903 |
T14911 |
nsubj |
inhalation,have |
R12916 |
T14904 |
T14903 |
prep |
of,inhalation |
R12917 |
T14905 |
T14904 |
pobj |
FP,of |
R12918 |
T14906 |
T14905 |
punct |
(,FP |
R12919 |
T14907 |
T14908 |
nummod |
500,µg |
R12920 |
T14908 |
T14905 |
appos |
µg,FP |
R12921 |
T14909 |
T14905 |
punct |
),FP |
R12922 |
T14910 |
T14911 |
aux |
may,have |
R12923 |
T14911 |
T14911 |
ROOT |
have,have |
R12924 |
T14912 |
T14913 |
amod |
comparable,effects |
R12925 |
T14913 |
T14911 |
dobj |
effects,have |
R12926 |
T14914 |
T14911 |
punct |
",",have |
R12927 |
T14915 |
T14917 |
mark |
as,provides |
R12928 |
T14916 |
T14917 |
nsubj |
it,provides |
R12929 |
T14917 |
T14911 |
advcl |
provides,have |
R12930 |
T14918 |
T14919 |
compound |
plasma,levels |
R12931 |
T14919 |
T14917 |
dobj |
levels,provides |
R12932 |
T14920 |
T14917 |
prep |
within,provides |
R12933 |
T14921 |
T14923 |
det |
a,range |
R12934 |
T14922 |
T14923 |
amod |
relevant,range |
R12935 |
T14923 |
T14920 |
pobj |
range,within |
R12936 |
T14924 |
T14923 |
prep |
of,range |
R12937 |
T14925 |
T14924 |
pobj |
concentrations,of |
R12938 |
T14926 |
T14911 |
advcl |
used,have |
R12939 |
T14927 |
T14928 |
aux |
to,suppress |
R12940 |
T14928 |
T14926 |
xcomp |
suppress,used |
R12941 |
T14929 |
T14930 |
compound |
IL-4,transcription |
R12942 |
T14930 |
T14928 |
dobj |
transcription,suppress |
R12943 |
T14931 |
T14928 |
prep |
in,suppress |
R12944 |
T14932 |
T14931 |
pobj |
our,in |
R12945 |
T14933 |
T14928 |
prep |
in,suppress |
R12946 |
T14934 |
T14935 |
amod |
vitro,system |
R12947 |
T14935 |
T14933 |
pobj |
system,in |
R12948 |
T14936 |
T14938 |
nmod |
[,] |
R12949 |
T14937 |
T14938 |
nummod |
37,] |
R12950 |
T14938 |
T14928 |
conj |
],suppress |
R12951 |
T14939 |
T14911 |
punct |
.,have |
R12952 |
T14940 |
T14942 |
det |
A,dose |
R12953 |
T14941 |
T14942 |
amod |
lower,dose |
R12954 |
T14942 |
T14950 |
nsubj |
dose,was |
R12955 |
T14943 |
T14942 |
prep |
of,dose |
R12956 |
T14944 |
T14945 |
amod |
inhaled,FP |
R12957 |
T14945 |
T14943 |
pobj |
FP,of |
R12958 |
T14946 |
T14945 |
punct |
(,FP |
R12959 |
T14947 |
T14948 |
nummod |
100,µg |
R12960 |
T14948 |
T14945 |
appos |
µg,FP |
R12961 |
T14949 |
T14948 |
punct |
),µg |
R12962 |
T14950 |
T14950 |
ROOT |
was,was |
R12963 |
T14951 |
T14950 |
neg |
not,was |
R12964 |
T14952 |
T14950 |
acomp |
effective,was |
R12965 |
T14953 |
T14950 |
punct |
",",was |
R12966 |
T14954 |
T14950 |
cc |
but,was |
R12967 |
T14955 |
T14956 |
compound |
plasma,concentrations |
R12968 |
T14956 |
T14958 |
nsubj |
concentrations,be |
R12969 |
T14957 |
T14958 |
aux |
may,be |
R12970 |
T14958 |
T14950 |
conj |
be,was |
R12971 |
T14959 |
T14958 |
prep |
below,be |
R12972 |
T14960 |
T14959 |
pobj |
those,below |
R12973 |
T14961 |
T14960 |
acl |
required,those |
R12974 |
T14962 |
T14961 |
prep |
for,required |
R12975 |
T14963 |
T14964 |
amod |
GATA-3,inhibition |
R12976 |
T14964 |
T14962 |
pobj |
inhibition,for |
R12977 |
T14965 |
T14958 |
punct |
.,be |
R12978 |
T14966 |
T14969 |
advmod |
However,is |
R12979 |
T14967 |
T14969 |
punct |
",",is |
R12980 |
T14968 |
T14969 |
nsubj |
it,is |
R12981 |
T14969 |
T14969 |
ROOT |
is,is |
R12982 |
T14970 |
T14969 |
acomp |
likely,is |
R12983 |
T14971 |
T14984 |
mark |
that,be |
R12984 |
T14972 |
T14974 |
det |
the,concentrations |
R12985 |
T14973 |
T14974 |
amod |
higher,concentrations |
R12986 |
T14974 |
T14984 |
nsubj |
concentrations,be |
R12987 |
T14975 |
T14974 |
prep |
of,concentrations |
R12988 |
T14976 |
T14975 |
pobj |
FP,of |
R12989 |
T14977 |
T14974 |
prep |
in,concentrations |
R12990 |
T14978 |
T14979 |
det |
the,airways |
R12991 |
T14979 |
T14977 |
pobj |
airways,in |
R12992 |
T14980 |
T14974 |
prep |
after,concentrations |
R12993 |
T14981 |
T14982 |
amod |
inhaled,administration |
R12994 |
T14982 |
T14980 |
pobj |
administration,after |
R12995 |
T14983 |
T14984 |
aux |
would,be |
R12996 |
T14984 |
T14970 |
ccomp |
be,likely |
R12997 |
T14985 |
T14984 |
acomp |
effective,be |
R12998 |
T14986 |
T14985 |
prep |
in,effective |
R12999 |
T14987 |
T14986 |
pcomp |
inhibiting,in |
R13000 |
T14988 |
T14987 |
dobj |
GATA-3,inhibiting |
R13001 |
T14989 |
T14987 |
prep |
in,inhibiting |
R13002 |
T14990 |
T14991 |
compound |
airway,T |
R13003 |
T14991 |
T14992 |
compound |
T,cells |
R13004 |
T14992 |
T14989 |
pobj |
cells,in |
R13005 |
T14993 |
T14992 |
prep |
of,cells |
R13006 |
T14994 |
T14995 |
compound |
asthma,patients |
R13007 |
T14995 |
T14993 |
pobj |
patients,of |
R13008 |
T14996 |
T14969 |
punct |
.,is |
R13009 |
T14997 |
T14998 |
det |
The,study |
R13010 |
T14998 |
T15010 |
nsubj |
study,demonstrates |
R13011 |
T14999 |
T14998 |
prep |
of,study |
R13012 |
T15000 |
T14999 |
pobj |
PBMCs,of |
R13013 |
T15001 |
T14998 |
prep |
from,study |
R13014 |
T15002 |
T15003 |
compound |
asthma,patients |
R13015 |
T15003 |
T15001 |
pobj |
patients,from |
R13016 |
T15004 |
T14998 |
acl |
treated,study |
R13017 |
T15005 |
T15004 |
prep |
with,treated |
R13018 |
T15006 |
T15008 |
amod |
inhaled,therapy |
R13019 |
T15007 |
T15008 |
amod |
corticosteroid,therapy |
R13020 |
T15008 |
T15005 |
pobj |
therapy,with |
R13021 |
T15009 |
T15010 |
advmod |
clearly,demonstrates |
R13022 |
T15010 |
T15010 |
ROOT |
demonstrates,demonstrates |
R13023 |
T15011 |
T15015 |
mark |
that,are |
R13024 |
T15012 |
T15014 |
det |
these,mechanisms |
R13025 |
T15013 |
T15014 |
amod |
molecular,mechanisms |
R13026 |
T15014 |
T15015 |
nsubj |
mechanisms,are |
R13027 |
T15015 |
T15010 |
ccomp |
are,demonstrates |
R13028 |
T15016 |
T15015 |
acomp |
likely,are |
R13029 |
T15017 |
T15019 |
aux |
to,occur |
R13030 |
T15018 |
T15019 |
advmod |
also,occur |
R13031 |
T15019 |
T15016 |
xcomp |
occur,likely |
R13032 |
T15020 |
T15019 |
prep |
in,occur |
R13033 |
T15021 |
T15020 |
pobj |
patients,in |
R13034 |
T15022 |
T15021 |
prep |
at,patients |
R13035 |
T15023 |
T15024 |
amod |
therapeutic,doses |
R13036 |
T15024 |
T15022 |
pobj |
doses,at |
R13037 |
T15025 |
T15024 |
prep |
of,doses |
R13038 |
T15026 |
T15027 |
amod |
inhaled,corticosteroids |
R13039 |
T15027 |
T15025 |
pobj |
corticosteroids,of |
R13040 |
T15028 |
T15010 |
punct |
.,demonstrates |
R13041 |
T15029 |
T15035 |
prep |
In,shown |
R13042 |
T15030 |
T15029 |
pobj |
addition,In |
R13043 |
T15031 |
T15035 |
punct |
",",shown |
R13044 |
T15032 |
T15033 |
amod |
previous,studies |
R13045 |
T15033 |
T15035 |
nsubj |
studies,shown |
R13046 |
T15034 |
T15035 |
aux |
have,shown |
R13047 |
T15035 |
T15035 |
ROOT |
shown,shown |
R13048 |
T15036 |
T15039 |
mark |
that,suppress |
R13049 |
T15037 |
T15039 |
nsubj |
corticosteroids,suppress |
R13050 |
T15038 |
T15039 |
aux |
can,suppress |
R13051 |
T15039 |
T15035 |
ccomp |
suppress,shown |
R13052 |
T15040 |
T15043 |
nmod |
IL-4,release |
R13053 |
T15041 |
T15040 |
cc |
and,IL-4 |
R13054 |
T15042 |
T15043 |
compound |
IL-5,release |
R13055 |
T15043 |
T15039 |
dobj |
release,suppress |
R13056 |
T15044 |
T15043 |
prep |
from,release |
R13057 |
T15045 |
T15047 |
amod |
peripheral,cells |
R13058 |
T15046 |
T15047 |
compound |
blood,cells |
R13059 |
T15047 |
T15044 |
pobj |
cells,from |
R13060 |
T15048 |
T15047 |
prep |
of,cells |
R13061 |
T15049 |
T15050 |
compound |
asthma,patients |
R13062 |
T15050 |
T15048 |
pobj |
patients,of |
R13063 |
T15051 |
T15043 |
prep |
in,release |
R13064 |
T15052 |
T15051 |
pobj |
vitro,in |
R13065 |
T15053 |
T15051 |
cc |
and,in |
R13066 |
T15054 |
T15051 |
conj |
in,in |
R13067 |
T15055 |
T15056 |
compound |
vivo,[ |
R13068 |
T15056 |
T15054 |
pobj |
[,in |
R13069 |
T15057 |
T15058 |
nummod |
40,] |
R13070 |
T15058 |
T15056 |
appos |
],[ |
R13071 |
T15059 |
T15056 |
appos |
[,[ |
R13072 |
T15060 |
T15061 |
nummod |
42,] |
R13073 |
T15061 |
T15056 |
appos |
],[ |
R13074 |
T15062 |
T15035 |
punct |
.,shown |
R13075 |
T15063 |
T15068 |
prep |
In,provide |
R13076 |
T15064 |
T15063 |
pobj |
summary,In |
R13077 |
T15065 |
T15068 |
punct |
",",provide |
R13078 |
T15066 |
T15067 |
poss |
our,data |
R13079 |
T15067 |
T15068 |
nsubj |
data,provide |
R13080 |
T15068 |
T15068 |
ROOT |
provide,provide |
R13081 |
T15069 |
T15068 |
dobj |
evidence,provide |
R13082 |
T15070 |
T15069 |
prep |
for,evidence |
R13083 |
T15071 |
T15073 |
det |
a,action |
R13084 |
T15072 |
T15073 |
compound |
novel,action |
R13085 |
T15073 |
T15070 |
pobj |
action,for |
R13086 |
T15074 |
T15073 |
prep |
of,action |
R13087 |
T15075 |
T15074 |
pobj |
corticosteroids,of |
R13088 |
T15076 |
T15069 |
punct |
:,evidence |
R13089 |
T15077 |
T15069 |
conj |
suppression,evidence |
R13090 |
T15078 |
T15077 |
prep |
of,suppression |
R13091 |
T15079 |
T15080 |
amod |
allergic,inflammation |
R13092 |
T15080 |
T15078 |
pobj |
inflammation,of |
R13093 |
T15081 |
T15068 |
prep |
through,provide |
R13094 |
T15082 |
T15085 |
det |
a,effect |
R13095 |
T15083 |
T15085 |
amod |
rapid,effect |
R13096 |
T15084 |
T15085 |
amod |
inhibitory,effect |
R13097 |
T15085 |
T15081 |
pobj |
effect,through |
R13098 |
T15086 |
T15085 |
prep |
on,effect |
R13099 |
T15087 |
T15089 |
amod |
GATA-3,translocation |
R13100 |
T15088 |
T15089 |
amod |
nuclear,translocation |
R13101 |
T15089 |
T15086 |
pobj |
translocation,on |
R13102 |
T15090 |
T15085 |
prep |
by,effect |
R13103 |
T15091 |
T15092 |
amod |
preferential,binding |
R13104 |
T15092 |
T15085 |
amod |
binding,effect |
R13105 |
T15093 |
T15092 |
prep |
to,binding |
R13106 |
T15094 |
T15098 |
det |
the,protein |
R13107 |
T15095 |
T15098 |
amod |
shared,protein |
R13108 |
T15096 |
T15097 |
amod |
nuclear,import |
R13109 |
T15097 |
T15098 |
compound |
import,protein |
R13110 |
T15098 |
T15099 |
compound |
protein,importin-α |
R13111 |
T15099 |
T15093 |
pobj |
importin-α,to |
R13112 |
T15100 |
T15081 |
cc |
and,through |
R13113 |
T15101 |
T15081 |
conj |
by,through |
R13114 |
T15102 |
T15104 |
det |
a,mechanism |
R13115 |
T15103 |
T15104 |
amod |
second,mechanism |
R13116 |
T15104 |
T15101 |
pobj |
mechanism,by |
R13117 |
T15105 |
T15104 |
acl |
involving,mechanism |
R13118 |
T15106 |
T15107 |
amod |
increased,synthesis |
R13119 |
T15107 |
T15068 |
dobj |
synthesis,provide |
R13120 |
T15108 |
T15107 |
prep |
of,synthesis |
R13121 |
T15109 |
T15108 |
pobj |
MKP-1,of |
R13122 |
T15110 |
T15109 |
punct |
",",MKP-1 |
R13123 |
T15111 |
T15112 |
nsubj |
which,inhibits |
R13124 |
T15112 |
T15109 |
relcl |
inhibits,MKP-1 |
R13125 |
T15113 |
T15114 |
nummod |
p38,MAPK |
R13126 |
T15114 |
T15112 |
dobj |
MAPK,inhibits |
R13127 |
T15115 |
T15068 |
punct |
",",provide |
R13128 |
T15116 |
T15117 |
advmod |
thus,preventing |
R13129 |
T15117 |
T15068 |
advcl |
preventing,provide |
R13130 |
T15118 |
T15119 |
det |
the,phosphorylation |
R13131 |
T15119 |
T15117 |
dobj |
phosphorylation,preventing |
R13132 |
T15120 |
T15119 |
prep |
of,phosphorylation |
R13133 |
T15121 |
T15120 |
pobj |
GATA-3,of |
R13134 |
T15122 |
T15123 |
nsubj |
that,is |
R13135 |
T15123 |
T15121 |
relcl |
is,GATA-3 |
R13136 |
T15124 |
T15123 |
acomp |
necessary,is |
R13137 |
T15125 |
T15124 |
prep |
for,necessary |
R13138 |
T15126 |
T15127 |
amod |
nuclear,translocation |
R13139 |
T15127 |
T15125 |
pobj |
translocation,for |
R13140 |
T15128 |
T15127 |
prep |
of,translocation |
R13141 |
T15129 |
T15128 |
pobj |
GATA-3,of |
R13142 |
T15130 |
T15068 |
punct |
.,provide |
R13143 |
T15131 |
T15133 |
det |
These,mechanisms |
R13144 |
T15132 |
T15133 |
nummod |
two,mechanisms |
R13145 |
T15133 |
T15134 |
nsubj |
mechanisms,are |
R13146 |
T15134 |
T15134 |
ROOT |
are,are |
R13147 |
T15135 |
T15134 |
acomp |
likely,are |
R13148 |
T15136 |
T15137 |
aux |
to,be |
R13149 |
T15137 |
T15135 |
xcomp |
be,likely |
R13150 |
T15138 |
T15137 |
acomp |
synergistic,be |
R13151 |
T15139 |
T15137 |
punct |
",",be |
R13152 |
T15140 |
T15137 |
advcl |
accounting,be |
R13153 |
T15141 |
T15140 |
prep |
for,accounting |
R13154 |
T15142 |
T15146 |
det |
the,effect |
R13155 |
T15143 |
T15146 |
amod |
rapid,effect |
R13156 |
T15144 |
T15143 |
cc |
and,rapid |
R13157 |
T15145 |
T15143 |
conj |
potent,rapid |
R13158 |
T15146 |
T15141 |
pobj |
effect,for |
R13159 |
T15147 |
T15146 |
prep |
of,effect |
R13160 |
T15148 |
T15147 |
pobj |
corticosteroids,of |
R13161 |
T15149 |
T15148 |
prep |
on,corticosteroids |
R13162 |
T15150 |
T15151 |
amod |
allergic,inflammation |
R13163 |
T15151 |
T15149 |
pobj |
inflammation,on |
R13164 |
T15152 |
T15134 |
punct |
.,are |
R13165 |
T15153 |
T15155 |
nsubjpass |
This,exemplified |
R13166 |
T15154 |
T15155 |
auxpass |
is,exemplified |
R13167 |
T15155 |
T15155 |
ROOT |
exemplified,exemplified |
R13168 |
T15156 |
T15155 |
agent |
by,exemplified |
R13169 |
T15157 |
T15160 |
det |
the,effect |
R13170 |
T15158 |
T15160 |
amod |
rapid,effect |
R13171 |
T15159 |
T15160 |
amod |
inhibitory,effect |
R13172 |
T15160 |
T15156 |
pobj |
effect,by |
R13173 |
T15161 |
T15160 |
prep |
of,effect |
R13174 |
T15162 |
T15163 |
amod |
topical,corticosteroids |
R13175 |
T15163 |
T15161 |
pobj |
corticosteroids,of |
R13176 |
T15164 |
T15163 |
prep |
on,corticosteroids |
R13177 |
T15165 |
T15168 |
amod |
nasal,release |
R13178 |
T15166 |
T15168 |
amod |
Th2,release |
R13179 |
T15167 |
T15168 |
compound |
cytokine,release |
R13180 |
T15168 |
T15164 |
pobj |
release,on |
R13181 |
T15169 |
T15155 |
prep |
after,exemplified |
R13182 |
T15170 |
T15171 |
compound |
allergen,provocation |
R13183 |
T15171 |
T15169 |
pobj |
provocation,after |
R13184 |
T15172 |
T15171 |
prep |
in,provocation |
R13185 |
T15173 |
T15172 |
pobj |
individuals,in |
R13186 |
T15174 |
T15173 |
prep |
with,individuals |
R13187 |
T15175 |
T15177 |
amod |
seasonal,rhinitis |
R13188 |
T15176 |
T15177 |
amod |
allergic,rhinitis |
R13189 |
T15177 |
T15174 |
pobj |
rhinitis,with |
R13190 |
T15178 |
T15177 |
punct |
(,rhinitis |
R13191 |
T15179 |
T15180 |
compound |
hay,fever |
R13192 |
T15180 |
T15177 |
appos |
fever,rhinitis |
R13193 |
T15181 |
T15177 |
punct |
),rhinitis |
R13194 |
T15182 |
T15184 |
quantmod |
[,] |
R13195 |
T15183 |
T15184 |
nummod |
43,] |
R13196 |
T15184 |
T15173 |
appos |
],individuals |
R13197 |
T15185 |
T15155 |
punct |
.,exemplified |
R13198 |
T15186 |
T15193 |
nsubj |
Prevention,provide |
R13199 |
T15187 |
T15186 |
prep |
of,Prevention |
R13200 |
T15188 |
T15189 |
amod |
phospho-GATA-3,interaction |
R13201 |
T15189 |
T15187 |
pobj |
interaction,of |
R13202 |
T15190 |
T15189 |
prep |
with,interaction |
R13203 |
T15191 |
T15190 |
pobj |
importin-α,with |
R13204 |
T15192 |
T15193 |
aux |
may,provide |
R13205 |
T15193 |
T15193 |
ROOT |
provide,provide |
R13206 |
T15194 |
T15196 |
det |
a,approach |
R13207 |
T15195 |
T15196 |
amod |
new,approach |
R13208 |
T15196 |
T15193 |
dobj |
approach,provide |
R13209 |
T15197 |
T15196 |
prep |
for,approach |
R13210 |
T15198 |
T15199 |
det |
the,development |
R13211 |
T15199 |
T15197 |
pobj |
development,for |
R13212 |
T15200 |
T15199 |
prep |
of,development |
R13213 |
T15201 |
T15202 |
compound |
novel,therapies |
R13214 |
T15202 |
T15200 |
pobj |
therapies,of |
R13215 |
T15203 |
T15202 |
prep |
for,therapies |
R13216 |
T15204 |
T15205 |
det |
the,treatment |
R13217 |
T15205 |
T15203 |
pobj |
treatment,for |
R13218 |
T15206 |
T15205 |
prep |
of,treatment |
R13219 |
T15207 |
T15208 |
amod |
allergic,diseases |
R13220 |
T15208 |
T15206 |
pobj |
diseases,of |
R13221 |
T15209 |
T15193 |
punct |
.,provide |
R14001 |
T16315 |
T16317 |
nmod |
Fluticasone,down-regulates |
R14002 |
T16316 |
T16317 |
amod |
propionate,down-regulates |
R14003 |
T16317 |
T16317 |
ROOT |
down-regulates,down-regulates |
R14004 |
T16318 |
T16321 |
nmod |
Th2,expression |
R14005 |
T16319 |
T16321 |
compound |
cytokine,expression |
R14006 |
T16320 |
T16321 |
compound |
gene,expression |
R14007 |
T16321 |
T16317 |
dobj |
expression,down-regulates |
R14008 |
T16322 |
T16321 |
cc |
and,expression |
R14009 |
T16323 |
T16317 |
conj |
inhibits,down-regulates |
R14010 |
T16324 |
T16326 |
nmod |
GATA-3,import |
R14011 |
T16325 |
T16326 |
amod |
nuclear,import |
R14012 |
T16326 |
T16323 |
dobj |
import,inhibits |
R14013 |
T16327 |
T16323 |
punct |
.,inhibits |
R14014 |
T16328 |
T16329 |
punct |
(,A |
R14015 |
T16329 |
T16329 |
ROOT |
A,A |
R14016 |
T16330 |
T16329 |
punct |
),A |
R14017 |
T16331 |
T16334 |
amod |
Anti-CD3,treatment |
R14018 |
T16332 |
T16334 |
nmod |
/,treatment |
R14019 |
T16333 |
T16334 |
nummod |
CD28,treatment |
R14020 |
T16334 |
T16334 |
ROOT |
treatment,treatment |
R14021 |
T16335 |
T16334 |
prep |
of,treatment |
R14022 |
T16336 |
T16337 |
amod |
HuT-78,cells |
R14023 |
T16337 |
T16338 |
compound |
cells,results |
R14024 |
T16338 |
T16335 |
pobj |
results,of |
R14025 |
T16339 |
T16338 |
prep |
in,results |
R14026 |
T16340 |
T16339 |
pobj |
translocation,in |
R14027 |
T16341 |
T16340 |
prep |
of,translocation |
R14028 |
T16342 |
T16341 |
pobj |
GATA-3,of |
R14029 |
T16343 |
T16334 |
prep |
from,treatment |
R14030 |
T16344 |
T16345 |
det |
the,cytoplasm |
R14031 |
T16345 |
T16343 |
pobj |
cytoplasm,from |
R14032 |
T16346 |
T16334 |
prep |
to,treatment |
R14033 |
T16347 |
T16348 |
det |
the,nucleus |
R14034 |
T16348 |
T16346 |
pobj |
nucleus,to |
R14035 |
T16349 |
T16334 |
prep |
within,treatment |
R14036 |
T16350 |
T16351 |
nummod |
30,min |
R14037 |
T16351 |
T16349 |
pobj |
min,within |
R14038 |
T16352 |
T16334 |
punct |
.,treatment |
R14039 |
T16353 |
T16361 |
punct |
(,used |
R14040 |
T16354 |
T16361 |
nsubjpass |
B,used |
R14041 |
T16355 |
T16354 |
punct |
),B |
R14042 |
T16356 |
T16357 |
compound |
Histone,H1 |
R14043 |
T16357 |
T16354 |
appos |
H1,B |
R14044 |
T16358 |
T16357 |
cc |
and,H1 |
R14045 |
T16359 |
T16357 |
conj |
MEK-1,H1 |
R14046 |
T16360 |
T16361 |
auxpass |
were,used |
R14047 |
T16361 |
T16361 |
ROOT |
used,used |
R14048 |
T16362 |
T16363 |
aux |
to,confirm |
R14049 |
T16363 |
T16361 |
xcomp |
confirm,used |
R14050 |
T16364 |
T16365 |
amod |
distinct,separation |
R14051 |
T16365 |
T16363 |
dobj |
separation,confirm |
R14052 |
T16366 |
T16365 |
prep |
of,separation |
R14053 |
T16367 |
T16370 |
amod |
cytoplasmic,extracts |
R14054 |
T16368 |
T16367 |
cc |
and,cytoplasmic |
R14055 |
T16369 |
T16367 |
conj |
nuclear,cytoplasmic |
R14056 |
T16370 |
T16366 |
pobj |
extracts,of |
R14057 |
T16371 |
T16363 |
prep |
in,confirm |
R14058 |
T16372 |
T16374 |
nummod |
three,experiments |
R14059 |
T16373 |
T16374 |
amod |
separate,experiments |
R14060 |
T16374 |
T16371 |
pobj |
experiments,in |
R14061 |
T16375 |
T16361 |
punct |
.,used |
R14062 |
T16376 |
T16377 |
punct |
(,C |
R14063 |
T16377 |
T16381 |
nmod |
C,analysis |
R14064 |
T16378 |
T16377 |
punct |
),C |
R14065 |
T16379 |
T16381 |
amod |
Western,analysis |
R14066 |
T16380 |
T16381 |
compound |
blot,analysis |
R14067 |
T16381 |
T16386 |
nsubj |
analysis,demonstrated |
R14068 |
T16382 |
T16381 |
prep |
of,analysis |
R14069 |
T16383 |
T16385 |
amod |
FP-treated,cells |
R14070 |
T16384 |
T16385 |
amod |
HuT-78,cells |
R14071 |
T16385 |
T16382 |
pobj |
cells,of |
R14072 |
T16386 |
T16386 |
ROOT |
demonstrated,demonstrated |
R14073 |
T16387 |
T16389 |
amod |
impaired,localization |
R14074 |
T16388 |
T16389 |
amod |
nuclear,localization |
R14075 |
T16389 |
T16386 |
dobj |
localization,demonstrated |
R14076 |
T16390 |
T16389 |
prep |
of,localization |
R14077 |
T16391 |
T16390 |
pobj |
GATA-3,of |
R14078 |
T16392 |
T16389 |
acl |
induced,localization |
R14079 |
T16393 |
T16392 |
agent |
by,induced |
R14080 |
T16394 |
T16397 |
amod |
anti-CD3,co-stimulation |
R14081 |
T16395 |
T16397 |
nmod |
/,co-stimulation |
R14082 |
T16396 |
T16397 |
nummod |
CD28,co-stimulation |
R14083 |
T16397 |
T16393 |
pobj |
co-stimulation,by |
R14084 |
T16398 |
T16392 |
prep |
in,induced |
R14085 |
T16399 |
T16400 |
det |
a,time |
R14086 |
T16400 |
T16398 |
pobj |
time,in |
R14087 |
T16401 |
T16389 |
punct |
-,localization |
R14088 |
T16402 |
T16389 |
punct |
(,localization |
R14089 |
T16403 |
T16389 |
prep |
at,localization |
R14090 |
T16404 |
T16405 |
nummod |
10,− |
R14091 |
T16405 |
T16408 |
nmod |
−,FP |
R14092 |
T16406 |
T16408 |
nummod |
8,FP |
R14093 |
T16407 |
T16408 |
compound |
M,FP |
R14094 |
T16408 |
T16403 |
pobj |
FP,at |
R14095 |
T16409 |
T16389 |
punct |
),localization |
R14096 |
T16410 |
T16389 |
cc |
and,localization |
R14097 |
T16411 |
T16389 |
conj |
concentration,localization |
R14098 |
T16412 |
T16389 |
punct |
-,localization |
R14099 |
T16413 |
T16389 |
punct |
(,localization |
R14100 |
T16414 |
T16386 |
prep |
at,demonstrated |
R14101 |
T16415 |
T16416 |
nummod |
60,min |
R14102 |
T16416 |
T16414 |
pobj |
min,at |
R14103 |
T16417 |
T16416 |
prep |
after,min |
R14104 |
T16418 |
T16417 |
pobj |
stimulation,after |
R14105 |
T16419 |
T16386 |
punct |
),demonstrated |
R14106 |
T16420 |
T16421 |
amod |
dependent,manner |
R14107 |
T16421 |
T16421 |
ROOT |
manner,manner |
R14108 |
T16422 |
T16421 |
punct |
.,manner |
R14109 |
T16423 |
T16425 |
nsubjpass |
Cells,pretreated |
R14110 |
T16424 |
T16425 |
auxpass |
were,pretreated |
R14111 |
T16425 |
T16425 |
ROOT |
pretreated,pretreated |
R14112 |
T16426 |
T16425 |
prep |
with,pretreated |
R14113 |
T16427 |
T16426 |
pobj |
FP,with |
R14114 |
T16428 |
T16425 |
prep |
for,pretreated |
R14115 |
T16429 |
T16430 |
nummod |
30,min |
R14116 |
T16430 |
T16428 |
pobj |
min,for |
R14117 |
T16431 |
T16425 |
advmod |
prior,pretreated |
R14118 |
T16432 |
T16431 |
prep |
to,prior |
R14119 |
T16433 |
T16432 |
pobj |
stimulation,to |
R14120 |
T16434 |
T16425 |
punct |
.,pretreated |
R14121 |
T16435 |
T16440 |
nsubjpass |
MEK1,used |
R14122 |
T16436 |
T16435 |
cc |
and,MEK1 |
R14123 |
T16437 |
T16438 |
compound |
histone,H1 |
R14124 |
T16438 |
T16435 |
conj |
H1,MEK1 |
R14125 |
T16439 |
T16440 |
auxpass |
were,used |
R14126 |
T16440 |
T16440 |
ROOT |
used,used |
R14127 |
T16441 |
T16442 |
aux |
to,demonstrate |
R14128 |
T16442 |
T16440 |
xcomp |
demonstrate,used |
R14129 |
T16443 |
T16444 |
amod |
equal,cytoplasmic |
R14130 |
T16444 |
T16442 |
dobj |
cytoplasmic,demonstrate |
R14131 |
T16445 |
T16444 |
cc |
and,cytoplasmic |
R14132 |
T16446 |
T16444 |
conj |
nuclear,cytoplasmic |
R14133 |
T16447 |
T16442 |
advcl |
loading,demonstrate |
R14134 |
T16448 |
T16447 |
advmod |
respectively,loading |
R14135 |
T16449 |
T16440 |
punct |
.,used |
R14136 |
T16450 |
T16452 |
nsubjpass |
Results,presented |
R14137 |
T16451 |
T16452 |
auxpass |
are,presented |
R14138 |
T16452 |
T16452 |
ROOT |
presented,presented |
R14139 |
T16453 |
T16454 |
advmod |
graphically,below |
R14140 |
T16454 |
T16452 |
prep |
below,presented |
R14141 |
T16455 |
T16452 |
prep |
as,presented |
R14142 |
T16456 |
T16458 |
amod |
mean,SEM |
R14143 |
T16457 |
T16458 |
compound |
±,SEM |
R14144 |
T16458 |
T16455 |
pobj |
SEM,as |
R14145 |
T16459 |
T16458 |
prep |
of,SEM |
R14146 |
T16460 |
T16461 |
advmod |
at,least |
R14147 |
T16461 |
T16462 |
advmod |
least,three |
R14148 |
T16462 |
T16464 |
nummod |
three,experiments |
R14149 |
T16463 |
T16464 |
amod |
independent,experiments |
R14150 |
T16464 |
T16459 |
pobj |
experiments,of |
R14151 |
T16465 |
T16452 |
punct |
.,presented |
R14152 |
T16466 |
T16468 |
compound |
***,< |
R14153 |
T16467 |
T16468 |
compound |
p,< |
R14154 |
T16468 |
T16470 |
nsubj |
<,compared |
R14155 |
T16469 |
T16468 |
nummod |
0.001,< |
R14156 |
T16470 |
T16470 |
ROOT |
compared,compared |
R14157 |
T16471 |
T16470 |
prep |
to,compared |
R14158 |
T16472 |
T16471 |
pobj |
t,to |
R14159 |
T16473 |
T16474 |
punct |
=,0 |
R14160 |
T16474 |
T16472 |
prep |
0,t |
R14161 |
T16475 |
T16470 |
punct |
.,compared |
R14162 |
T16476 |
T16479 |
punct |
(,RT-PCR |
R14163 |
T16477 |
T16479 |
nmod |
D,RT-PCR |
R14164 |
T16478 |
T16479 |
punct |
),RT-PCR |
R14165 |
T16479 |
T16479 |
ROOT |
RT-PCR,RT-PCR |
R14166 |
T16480 |
T16479 |
acl |
showing,RT-PCR |
R14167 |
T16481 |
T16483 |
mark |
that,inhibits |
R14168 |
T16482 |
T16483 |
nsubj |
FP,inhibits |
R14169 |
T16483 |
T16480 |
ccomp |
inhibits,showing |
R14170 |
T16484 |
T16488 |
nmod |
IL-4,expression |
R14171 |
T16485 |
T16484 |
cc |
and,IL-4 |
R14172 |
T16486 |
T16484 |
conj |
IL-5,IL-4 |
R14173 |
T16487 |
T16488 |
compound |
mRNA,expression |
R14174 |
T16488 |
T16483 |
dobj |
expression,inhibits |
R14175 |
T16489 |
T16488 |
prep |
in,expression |
R14176 |
T16490 |
T16491 |
amod |
CD3/CD28-costimulated,cells |
R14177 |
T16491 |
T16489 |
pobj |
cells,in |
R14178 |
T16492 |
T16479 |
punct |
.,RT-PCR |
R14179 |
T16493 |
T16495 |
nsubjpass |
GAPDH,used |
R14180 |
T16494 |
T16495 |
auxpass |
was,used |
R14181 |
T16495 |
T16495 |
ROOT |
used,used |
R14182 |
T16496 |
T16495 |
prep |
as,used |
R14183 |
T16497 |
T16499 |
det |
a,control |
R14184 |
T16498 |
T16499 |
compound |
loading,control |
R14185 |
T16499 |
T16496 |
pobj |
control,as |
R14186 |
T16500 |
T16495 |
punct |
.,used |
R14187 |
T16501 |
T16502 |
amod |
Lower,panels |
R14188 |
T16502 |
T16503 |
nsubj |
panels,show |
R14189 |
T16503 |
T16503 |
ROOT |
show,show |
R14190 |
T16504 |
T16505 |
amod |
graphical,analysis |
R14191 |
T16505 |
T16503 |
dobj |
analysis,show |
R14192 |
T16506 |
T16505 |
prep |
of,analysis |
R14193 |
T16507 |
T16506 |
pobj |
results,of |
R14194 |
T16508 |
T16507 |
acl |
presented,results |
R14195 |
T16509 |
T16508 |
prep |
as,presented |
R14196 |
T16510 |
T16512 |
amod |
mean,SEM |
R14197 |
T16511 |
T16512 |
compound |
±,SEM |
R14198 |
T16512 |
T16509 |
pobj |
SEM,as |
R14199 |
T16513 |
T16512 |
prep |
of,SEM |
R14200 |
T16514 |
T16515 |
advmod |
at,least |
R14201 |
T16515 |
T16516 |
advmod |
least,three |
R14202 |
T16516 |
T16518 |
nummod |
three,experiments |
R14203 |
T16517 |
T16518 |
amod |
independent,experiments |
R14204 |
T16518 |
T16513 |
pobj |
experiments,of |
R14205 |
T16519 |
T16503 |
punct |
.,show |
R14206 |
T16520 |
T16522 |
dep |
###,< |
R14207 |
T16521 |
T16522 |
nmod |
p,< |
R14208 |
T16522 |
T16522 |
ROOT |
<,< |
R14209 |
T16523 |
T16532 |
nsubj |
0.001,compared |
R14210 |
T16524 |
T16532 |
prep |
compared,compared |
R14211 |
T16525 |
T16526 |
aux |
to,control |
R14212 |
T16526 |
T16524 |
xcomp |
control,compared |
R14213 |
T16527 |
T16532 |
punct |
",",compared |
R14214 |
T16528 |
T16531 |
nmod |
***,0.001 |
R14215 |
T16529 |
T16531 |
nmod |
p,0.001 |
R14216 |
T16530 |
T16531 |
nmod |
<,0.001 |
R14217 |
T16531 |
T16532 |
nsubj |
0.001,compared |
R14218 |
T16532 |
T16532 |
ROOT |
compared,compared |
R14219 |
T16533 |
T16532 |
prep |
to,compared |
R14220 |
T16534 |
T16535 |
compound |
anti-CD3,/ |
R14221 |
T16535 |
T16536 |
compound |
/,CD28 |
R14222 |
T16536 |
T16533 |
pobj |
CD28,to |
R14223 |
T16537 |
T16536 |
acl |
stimulated,CD28 |
R14224 |
T16538 |
T16532 |
punct |
.,compared |
R14225 |
T16539 |
T16542 |
punct |
(,FP |
R14226 |
T16540 |
T16542 |
nmod |
E,FP |
R14227 |
T16541 |
T16542 |
punct |
),FP |
R14228 |
T16542 |
T16547 |
nsubj |
FP,reduces |
R14229 |
T16543 |
T16545 |
punct |
(,nM |
R14230 |
T16544 |
T16545 |
nummod |
10,nM |
R14231 |
T16545 |
T16542 |
appos |
nM,FP |
R14232 |
T16546 |
T16542 |
punct |
),FP |
R14233 |
T16547 |
T16547 |
ROOT |
reduces,reduces |
R14234 |
T16548 |
T16549 |
det |
the,ability |
R14235 |
T16549 |
T16547 |
dobj |
ability,reduces |
R14236 |
T16550 |
T16549 |
prep |
of,ability |
R14237 |
T16551 |
T16554 |
amod |
anti-CD3,GATA-3 |
R14238 |
T16552 |
T16554 |
nmod |
/,GATA-3 |
R14239 |
T16553 |
T16554 |
amod |
CD28-stimulated,GATA-3 |
R14240 |
T16554 |
T16550 |
pobj |
GATA-3,of |
R14241 |
T16555 |
T16556 |
aux |
to,associate |
R14242 |
T16556 |
T16549 |
acl |
associate,ability |
R14243 |
T16557 |
T16556 |
prep |
with,associate |
R14244 |
T16558 |
T16561 |
det |
the,promoter |
R14245 |
T16559 |
T16561 |
amod |
native,promoter |
R14246 |
T16560 |
T16561 |
compound |
IL-5,promoter |
R14247 |
T16561 |
T16557 |
pobj |
promoter,with |
R14248 |
T16562 |
T16563 |
nummod |
60,min |
R14249 |
T16563 |
T16561 |
appos |
min,promoter |
R14250 |
T16564 |
T16563 |
prep |
after,min |
R14251 |
T16565 |
T16564 |
pobj |
stimulation,after |
R14252 |
T16566 |
T16547 |
punct |
.,reduces |
R14253 |
T16567 |
T16570 |
nsubjpass |
Data,shown |
R14254 |
T16568 |
T16570 |
auxpass |
are,shown |
R14255 |
T16569 |
T16570 |
advmod |
also,shown |
R14256 |
T16570 |
T16570 |
ROOT |
shown,shown |
R14257 |
T16571 |
T16570 |
advmod |
graphically,shown |
R14258 |
T16572 |
T16570 |
prep |
as,shown |
R14259 |
T16573 |
T16575 |
amod |
mean,SEM |
R14260 |
T16574 |
T16575 |
compound |
±,SEM |
R14261 |
T16575 |
T16572 |
pobj |
SEM,as |
R14262 |
T16576 |
T16575 |
prep |
of,SEM |
R14263 |
T16577 |
T16579 |
nummod |
three,experiments |
R14264 |
T16578 |
T16579 |
amod |
independent,experiments |
R14265 |
T16579 |
T16576 |
pobj |
experiments,of |
R14266 |
T16580 |
T16570 |
punct |
.,shown |
R14267 |
T16581 |
T16582 |
det |
All,data |
R14268 |
T16582 |
T16584 |
nsubjpass |
data,analysed |
R14269 |
T16583 |
T16584 |
auxpass |
were,analysed |
R14270 |
T16584 |
T16584 |
ROOT |
analysed,analysed |
R14271 |
T16585 |
T16584 |
agent |
by,analysed |
R14272 |
T16586 |
T16585 |
pobj |
ANOVA,by |
R14273 |
T16587 |
T16584 |
acl |
followed,analysed |
R14274 |
T16588 |
T16587 |
agent |
by,followed |
R14275 |
T16589 |
T16588 |
pobj |
Newman-Keuls,by |
R14276 |
T16590 |
T16590 |
ROOT |
post-test,post-test |
R14277 |
T16591 |
T16584 |
punct |
.,analysed |
R14667 |
T17105 |
T17106 |
compound |
Fluticasone,propionate |
R14668 |
T17106 |
T17107 |
nsubj |
propionate,reduces |
R14669 |
T17107 |
T17107 |
ROOT |
reduces,reduces |
R14670 |
T17108 |
T17109 |
amod |
GATA-3,association |
R14671 |
T17109 |
T17107 |
dobj |
association,reduces |
R14672 |
T17110 |
T17109 |
prep |
with,association |
R14673 |
T17111 |
T17115 |
amod |
importin-α,import |
R14674 |
T17112 |
T17111 |
cc |
and,importin-α |
R14675 |
T17113 |
T17111 |
conj |
GATA-3,importin-α |
R14676 |
T17114 |
T17115 |
amod |
nuclear,import |
R14677 |
T17115 |
T17110 |
pobj |
import,with |
R14678 |
T17116 |
T17107 |
punct |
.,reduces |
R14679 |
T17117 |
T17118 |
punct |
(,A |
R14680 |
T17118 |
T17122 |
nmod |
A,analysis |
R14681 |
T17119 |
T17118 |
punct |
),A |
R14682 |
T17120 |
T17122 |
amod |
Western,analysis |
R14683 |
T17121 |
T17122 |
compound |
blot,analysis |
R14684 |
T17122 |
T17123 |
nsubj |
analysis,demonstrates |
R14685 |
T17123 |
T17123 |
ROOT |
demonstrates,demonstrates |
R14686 |
T17124 |
T17133 |
det |
a,FP |
R14687 |
T17125 |
T17133 |
nmod |
time,FP |
R14688 |
T17126 |
T17133 |
punct |
-,FP |
R14689 |
T17127 |
T17133 |
punct |
(,FP |
R14690 |
T17128 |
T17133 |
prep |
at,FP |
R14691 |
T17129 |
T17131 |
quantmod |
10,8 |
R14692 |
T17130 |
T17131 |
quantmod |
−,8 |
R14693 |
T17131 |
T17128 |
pobj |
8,at |
R14694 |
T17132 |
T17133 |
compound |
M,FP |
R14695 |
T17133 |
T17123 |
dobj |
FP,demonstrates |
R14696 |
T17134 |
T17123 |
punct |
),demonstrates |
R14697 |
T17135 |
T17123 |
cc |
and,demonstrates |
R14698 |
T17136 |
T17123 |
conj |
concentration,demonstrates |
R14699 |
T17137 |
T17136 |
punct |
-,concentration |
R14700 |
T17138 |
T17141 |
punct |
(,min |
R14701 |
T17139 |
T17141 |
prep |
at,min |
R14702 |
T17140 |
T17141 |
nummod |
60,min |
R14703 |
T17141 |
T17136 |
appos |
min,concentration |
R14704 |
T17142 |
T17141 |
prep |
after,min |
R14705 |
T17143 |
T17142 |
pobj |
stimulation,after |
R14706 |
T17144 |
T17141 |
punct |
),min |
R14707 |
T17145 |
T17146 |
amod |
dependent,induction |
R14708 |
T17146 |
T17136 |
conj |
induction,concentration |
R14709 |
T17147 |
T17146 |
prep |
of,induction |
R14710 |
T17148 |
T17150 |
amod |
FP-activated,interaction |
R14711 |
T17149 |
T17150 |
compound |
GR,interaction |
R14712 |
T17150 |
T17147 |
pobj |
interaction,of |
R14713 |
T17151 |
T17150 |
prep |
with,interaction |
R14714 |
T17152 |
T17151 |
pobj |
importin-α,with |
R14715 |
T17153 |
T17154 |
punct |
(,Imp-α |
R14716 |
T17154 |
T17152 |
appos |
Imp-α,importin-α |
R14717 |
T17155 |
T17154 |
punct |
),Imp-α |
R14718 |
T17156 |
T17123 |
punct |
.,demonstrates |
R14719 |
T17157 |
T17159 |
det |
A,control |
R14720 |
T17158 |
T17159 |
amod |
positive,control |
R14721 |
T17159 |
T17166 |
nsubjpass |
control,shown |
R14722 |
T17160 |
T17159 |
prep |
for,control |
R14723 |
T17161 |
T17162 |
compound |
GR,association |
R14724 |
T17162 |
T17160 |
pobj |
association,for |
R14725 |
T17163 |
T17162 |
prep |
with,association |
R14726 |
T17164 |
T17163 |
pobj |
importin,with |
R14727 |
T17165 |
T17166 |
auxpass |
is,shown |
R14728 |
T17166 |
T17166 |
ROOT |
shown,shown |
R14729 |
T17167 |
T17166 |
punct |
.,shown |
R14730 |
T17168 |
T17174 |
nsubjpass |
Quantification,shown |
R14731 |
T17169 |
T17168 |
prep |
of,Quantification |
R14732 |
T17170 |
T17172 |
det |
the,data |
R14733 |
T17171 |
T17172 |
compound |
densitometry,data |
R14734 |
T17172 |
T17169 |
pobj |
data,of |
R14735 |
T17173 |
T17174 |
auxpass |
is,shown |
R14736 |
T17174 |
T17174 |
ROOT |
shown,shown |
R14737 |
T17175 |
T17174 |
prep |
below,shown |
R14738 |
T17176 |
T17174 |
punct |
.,shown |
R14739 |
T17177 |
T17178 |
det |
Each,bar |
R14740 |
T17178 |
T17179 |
nsubj |
bar,represents |
R14741 |
T17179 |
T17179 |
ROOT |
represents,represents |
R14742 |
T17180 |
T17182 |
amod |
mean,SEM |
R14743 |
T17181 |
T17182 |
compound |
±,SEM |
R14744 |
T17182 |
T17179 |
dobj |
SEM,represents |
R14745 |
T17183 |
T17182 |
prep |
of,SEM |
R14746 |
T17184 |
T17185 |
advmod |
at,least |
R14747 |
T17185 |
T17186 |
advmod |
least,three |
R14748 |
T17186 |
T17188 |
nummod |
three,experiments |
R14749 |
T17187 |
T17188 |
amod |
independent,experiments |
R14750 |
T17188 |
T17183 |
pobj |
experiments,of |
R14751 |
T17189 |
T17179 |
punct |
.,represents |
R14752 |
T17190 |
T17192 |
nmod |
***,< |
R14753 |
T17191 |
T17192 |
nmod |
p,< |
R14754 |
T17192 |
T17193 |
nmod |
<,0.001 |
R14755 |
T17193 |
T17194 |
nsubj |
0.001,compared |
R14756 |
T17194 |
T17194 |
ROOT |
compared,compared |
R14757 |
T17195 |
T17196 |
aux |
to,control |
R14758 |
T17196 |
T17194 |
xcomp |
control,compared |
R14759 |
T17197 |
T17200 |
punct |
",",< |
R14760 |
T17198 |
T17200 |
dep |
###,< |
R14761 |
T17199 |
T17200 |
dep |
p,< |
R14762 |
T17200 |
T17201 |
nmod |
<,0.001 |
R14763 |
T17201 |
T17194 |
dobj |
0.001,compared |
R14764 |
T17202 |
T17194 |
punct |
.,compared |
R14765 |
T17203 |
T17209 |
punct |
(,demonstrated |
R14766 |
T17204 |
T17208 |
nmod |
B,analysis |
R14767 |
T17205 |
T17204 |
punct |
),B |
R14768 |
T17206 |
T17208 |
compound |
Western,analysis |
R14769 |
T17207 |
T17208 |
compound |
blot,analysis |
R14770 |
T17208 |
T17209 |
nsubj |
analysis,demonstrated |
R14771 |
T17209 |
T17209 |
ROOT |
demonstrated,demonstrated |
R14772 |
T17210 |
T17232 |
det |
a,induction |
R14773 |
T17211 |
T17232 |
npadvmod |
time,induction |
R14774 |
T17212 |
T17232 |
punct |
-,induction |
R14775 |
T17213 |
T17232 |
punct |
(,induction |
R14776 |
T17214 |
T17232 |
nmod |
at,induction |
R14777 |
T17215 |
T17219 |
nummod |
10,FP |
R14778 |
T17216 |
T17217 |
quantmod |
−,8 |
R14779 |
T17217 |
T17219 |
nummod |
8,FP |
R14780 |
T17218 |
T17219 |
compound |
M,FP |
R14781 |
T17219 |
T17214 |
pobj |
FP,at |
R14782 |
T17220 |
T17214 |
punct |
),at |
R14783 |
T17221 |
T17214 |
cc |
and,at |
R14784 |
T17222 |
T17214 |
conj |
concentration,at |
R14785 |
T17223 |
T17222 |
punct |
-,concentration |
R14786 |
T17224 |
T17222 |
punct |
(,concentration |
R14787 |
T17225 |
T17222 |
prep |
at,concentration |
R14788 |
T17226 |
T17227 |
nummod |
60,min |
R14789 |
T17227 |
T17225 |
pobj |
min,at |
R14790 |
T17228 |
T17227 |
prep |
after,min |
R14791 |
T17229 |
T17228 |
pobj |
stimulation,after |
R14792 |
T17230 |
T17222 |
punct |
),concentration |
R14793 |
T17231 |
T17232 |
amod |
dependent,induction |
R14794 |
T17232 |
T17209 |
dobj |
induction,demonstrated |
R14795 |
T17233 |
T17232 |
prep |
of,induction |
R14796 |
T17234 |
T17237 |
amod |
FP-activated,translocation |
R14797 |
T17235 |
T17237 |
nmod |
GR,translocation |
R14798 |
T17236 |
T17237 |
amod |
nuclear,translocation |
R14799 |
T17237 |
T17238 |
npadvmod |
translocation,measured |
R14800 |
T17238 |
T17232 |
acl |
measured,induction |
R14801 |
T17239 |
T17238 |
agent |
by,measured |
R14802 |
T17240 |
T17239 |
pobj |
IP,by |
R14803 |
T17241 |
T17209 |
punct |
.,demonstrated |
R14804 |
T17242 |
T17248 |
nsubjpass |
Quantification,shown |
R14805 |
T17243 |
T17242 |
prep |
of,Quantification |
R14806 |
T17244 |
T17246 |
det |
the,data |
R14807 |
T17245 |
T17246 |
compound |
densitometry,data |
R14808 |
T17246 |
T17243 |
pobj |
data,of |
R14809 |
T17247 |
T17248 |
auxpass |
is,shown |
R14810 |
T17248 |
T17248 |
ROOT |
shown,shown |
R14811 |
T17249 |
T17248 |
prep |
below,shown |
R14812 |
T17250 |
T17248 |
punct |
.,shown |
R14813 |
T17251 |
T17252 |
det |
Each,bar |
R14814 |
T17252 |
T17253 |
nsubj |
bar,represents |
R14815 |
T17253 |
T17253 |
ROOT |
represents,represents |
R14816 |
T17254 |
T17256 |
amod |
mean,SEM |
R14817 |
T17255 |
T17256 |
compound |
±,SEM |
R14818 |
T17256 |
T17253 |
dobj |
SEM,represents |
R14819 |
T17257 |
T17256 |
prep |
of,SEM |
R14820 |
T17258 |
T17259 |
advmod |
at,least |
R14821 |
T17259 |
T17260 |
advmod |
least,three |
R14822 |
T17260 |
T17262 |
nummod |
three,experiments |
R14823 |
T17261 |
T17262 |
amod |
independent,experiments |
R14824 |
T17262 |
T17257 |
pobj |
experiments,of |
R14825 |
T17263 |
T17253 |
punct |
.,represents |
R14826 |
T17264 |
T17266 |
compound |
***,< |
R14827 |
T17265 |
T17266 |
compound |
p,< |
R14828 |
T17266 |
T17268 |
nsubj |
<,compared |
R14829 |
T17267 |
T17266 |
nummod |
0.001,< |
R14830 |
T17268 |
T17268 |
ROOT |
compared,compared |
R14831 |
T17269 |
T17270 |
aux |
to,control |
R14832 |
T17270 |
T17268 |
xcomp |
control,compared |
R14833 |
T17271 |
T17268 |
punct |
.,compared |
R14834 |
T17272 |
T17273 |
punct |
(,C |
R14835 |
T17273 |
T17277 |
nmod |
C,analysis |
R14836 |
T17274 |
T17273 |
punct |
),C |
R14837 |
T17275 |
T17277 |
amod |
Western,analysis |
R14838 |
T17276 |
T17277 |
compound |
blot,analysis |
R14839 |
T17277 |
T17289 |
nsubj |
analysis,demonstrated |
R14840 |
T17278 |
T17277 |
prep |
of,analysis |
R14841 |
T17279 |
T17280 |
amod |
HuT-78,cells |
R14842 |
T17280 |
T17278 |
pobj |
cells,of |
R14843 |
T17281 |
T17280 |
acl |
treated,cells |
R14844 |
T17282 |
T17281 |
prep |
with,treated |
R14845 |
T17283 |
T17282 |
pobj |
FP,with |
R14846 |
T17284 |
T17283 |
cc |
and,FP |
R14847 |
T17285 |
T17286 |
compound |
anti-CD3,/ |
R14848 |
T17286 |
T17283 |
conj |
/,FP |
R14849 |
T17287 |
T17288 |
nummod |
CD28,co-stimulation |
R14850 |
T17288 |
T17289 |
nsubj |
co-stimulation,demonstrated |
R14851 |
T17289 |
T17289 |
ROOT |
demonstrated,demonstrated |
R14852 |
T17290 |
T17292 |
det |
a,decrease |
R14853 |
T17291 |
T17292 |
amod |
concentration-dependent,decrease |
R14854 |
T17292 |
T17289 |
dobj |
decrease,demonstrated |
R14855 |
T17293 |
T17292 |
prep |
in,decrease |
R14856 |
T17294 |
T17293 |
pobj |
GATA-3,in |
R14857 |
T17295 |
T17296 |
compound |
importin-α,association |
R14858 |
T17296 |
T17292 |
appos |
association,decrease |
R14859 |
T17297 |
T17292 |
prep |
at,decrease |
R14860 |
T17298 |
T17299 |
nummod |
20,min |
R14861 |
T17299 |
T17297 |
pobj |
min,at |
R14862 |
T17300 |
T17289 |
punct |
.,demonstrated |
R14863 |
T17301 |
T17307 |
nsubjpass |
Quantification,shown |
R14864 |
T17302 |
T17301 |
prep |
of,Quantification |
R14865 |
T17303 |
T17305 |
det |
the,data |
R14866 |
T17304 |
T17305 |
compound |
densitometry,data |
R14867 |
T17305 |
T17302 |
pobj |
data,of |
R14868 |
T17306 |
T17307 |
auxpass |
is,shown |
R14869 |
T17307 |
T17307 |
ROOT |
shown,shown |
R14870 |
T17308 |
T17307 |
prep |
below,shown |
R14871 |
T17309 |
T17307 |
punct |
.,shown |
R14872 |
T17310 |
T17311 |
det |
Each,bar |
R14873 |
T17311 |
T17312 |
nsubj |
bar,represents |
R14874 |
T17312 |
T17312 |
ROOT |
represents,represents |
R14875 |
T17313 |
T17315 |
amod |
mean,SEM |
R14876 |
T17314 |
T17315 |
compound |
±,SEM |
R14877 |
T17315 |
T17312 |
dobj |
SEM,represents |
R14878 |
T17316 |
T17315 |
prep |
of,SEM |
R14879 |
T17317 |
T17318 |
advmod |
at,least |
R14880 |
T17318 |
T17319 |
advmod |
least,three |
R14881 |
T17319 |
T17321 |
nummod |
three,experiments |
R14882 |
T17320 |
T17321 |
amod |
independent,experiments |
R14883 |
T17321 |
T17316 |
pobj |
experiments,of |
R14884 |
T17322 |
T17312 |
punct |
.,represents |
R14885 |
T17323 |
T17325 |
dep |
###,< |
R14886 |
T17324 |
T17325 |
compound |
p,< |
R14887 |
T17325 |
T17325 |
ROOT |
<,< |
R14888 |
T17326 |
T17326 |
ROOT |
0.001,0.001 |
R14889 |
T17327 |
T17335 |
prep |
compared,compared |
R14890 |
T17328 |
T17329 |
aux |
to,control |
R14891 |
T17329 |
T17327 |
xcomp |
control,compared |
R14892 |
T17330 |
T17333 |
punct |
",",< |
R14893 |
T17331 |
T17333 |
nmod |
***,< |
R14894 |
T17332 |
T17333 |
nmod |
p,< |
R14895 |
T17333 |
T17334 |
nmod |
<,0.001 |
R14896 |
T17334 |
T17335 |
npadvmod |
0.001,compared |
R14897 |
T17335 |
T17326 |
prep |
compared,0.001 |
R14898 |
T17336 |
T17335 |
prep |
to,compared |
R14899 |
T17337 |
T17336 |
pobj |
αCD3,to |
R14900 |
T17338 |
T17340 |
amod |
/,cells |
R14901 |
T17339 |
T17340 |
amod |
CD28-stimulated,cells |
R14902 |
T17340 |
T17337 |
dobj |
cells,αCD3 |
R14903 |
T17341 |
T17326 |
punct |
.,0.001 |
R14904 |
T17342 |
T17343 |
punct |
(,D |
R14905 |
T17343 |
T17343 |
ROOT |
D,D |
R14906 |
T17344 |
T17343 |
punct |
),D |
R14907 |
T17345 |
T17346 |
amod |
GFP-tagged,GATA-3 |
R14908 |
T17346 |
T17348 |
nsubjpass |
GATA-3,overexpressed |
R14909 |
T17347 |
T17348 |
auxpass |
was,overexpressed |
R14910 |
T17348 |
T17348 |
ROOT |
overexpressed,overexpressed |
R14911 |
T17349 |
T17348 |
cc |
and,overexpressed |
R14912 |
T17350 |
T17348 |
conj |
cells,overexpressed |
R14913 |
T17351 |
T17350 |
acl |
stimulated,cells |
R14914 |
T17352 |
T17355 |
punct |
(,c |
R14915 |
T17353 |
T17355 |
nmod |
b,c |
R14916 |
T17354 |
T17355 |
punct |
",",c |
R14917 |
T17355 |
T17351 |
appos |
c,stimulated |
R14918 |
T17356 |
T17355 |
punct |
),c |
R14919 |
T17357 |
T17355 |
cc |
or,c |
R14920 |
T17358 |
T17359 |
neg |
not,( |
R14921 |
T17359 |
T17360 |
punct |
(,a |
R14922 |
T17360 |
T17362 |
meta |
a,for |
R14923 |
T17361 |
T17360 |
punct |
),a |
R14924 |
T17362 |
T17355 |
conj |
for,c |
R14925 |
T17363 |
T17364 |
nummod |
30,min |
R14926 |
T17364 |
T17362 |
pobj |
min,for |
R14927 |
T17365 |
T17364 |
prep |
with,min |
R14928 |
T17366 |
T17367 |
compound |
anti-CD3,/ |
R14929 |
T17367 |
T17368 |
compound |
/,CD28 |
R14930 |
T17368 |
T17365 |
pobj |
CD28,with |
R14931 |
T17369 |
T17348 |
punct |
.,overexpressed |
R14932 |
T17370 |
T17371 |
det |
The,effect |
R14933 |
T17371 |
T17390 |
nsubjpass |
effect,shown |
R14934 |
T17372 |
T17371 |
prep |
of,effect |
R14935 |
T17373 |
T17375 |
nummod |
30,pretreatment |
R14936 |
T17374 |
T17375 |
compound |
min,pretreatment |
R14937 |
T17375 |
T17372 |
pobj |
pretreatment,of |
R14938 |
T17376 |
T17375 |
prep |
of,pretreatment |
R14939 |
T17377 |
T17376 |
pobj |
cells,of |
R14940 |
T17378 |
T17371 |
prep |
with,effect |
R14941 |
T17379 |
T17378 |
pobj |
FP,with |
R14942 |
T17380 |
T17379 |
punct |
(,FP |
R14943 |
T17381 |
T17382 |
nummod |
10,− |
R14944 |
T17382 |
T17379 |
appos |
−,FP |
R14945 |
T17383 |
T17384 |
nummod |
8,M |
R14946 |
T17384 |
T17390 |
nsubjpass |
M,shown |
R14947 |
T17385 |
T17384 |
punct |
",",M |
R14948 |
T17386 |
T17384 |
appos |
c,M |
R14949 |
T17387 |
T17384 |
punct |
),M |
R14950 |
T17388 |
T17390 |
auxpass |
is,shown |
R14951 |
T17389 |
T17390 |
advmod |
also,shown |
R14952 |
T17390 |
T17390 |
ROOT |
shown,shown |
R14953 |
T17391 |
T17390 |
punct |
.,shown |
R14954 |
T17392 |
T17393 |
det |
All,data |
R14955 |
T17393 |
T17395 |
nsubjpass |
data,analysed |
R14956 |
T17394 |
T17395 |
auxpass |
were,analysed |
R14957 |
T17395 |
T17395 |
ROOT |
analysed,analysed |
R14958 |
T17396 |
T17395 |
agent |
by,analysed |
R14959 |
T17397 |
T17396 |
pobj |
ANOVA,by |
R14960 |
T17398 |
T17395 |
prep |
followed,analysed |
R14961 |
T17399 |
T17398 |
agent |
by,followed |
R14962 |
T17400 |
T17399 |
pobj |
Newman-Keuls,by |
R14963 |
T17401 |
T17395 |
conj |
post-test,analysed |
R14964 |
T17402 |
T17395 |
punct |
.,analysed |
R15301 |
T17853 |
T17854 |
compound |
Fluticasone,propionate |
R15302 |
T17854 |
T17854 |
ROOT |
propionate,propionate |
R15303 |
T17855 |
T17865 |
nsubjpass |
mediated,associated |
R15304 |
T17856 |
T17855 |
dobj |
inhibition,mediated |
R15305 |
T17857 |
T17856 |
prep |
of,inhibition |
R15306 |
T17858 |
T17861 |
nummod |
p38,phosphorylation |
R15307 |
T17859 |
T17861 |
nmod |
MAP,phosphorylation |
R15308 |
T17860 |
T17861 |
compound |
kinase,phosphorylation |
R15309 |
T17861 |
T17857 |
pobj |
phosphorylation,of |
R15310 |
T17862 |
T17861 |
cc |
and,phosphorylation |
R15311 |
T17863 |
T17861 |
conj |
activation,phosphorylation |
R15312 |
T17864 |
T17865 |
auxpass |
is,associated |
R15313 |
T17865 |
T17865 |
ROOT |
associated,associated |
R15314 |
T17866 |
T17865 |
prep |
with,associated |
R15315 |
T17867 |
T17869 |
det |
a,down-regulation |
R15316 |
T17868 |
T17869 |
amod |
marked,down-regulation |
R15317 |
T17869 |
T17866 |
pobj |
down-regulation,with |
R15318 |
T17870 |
T17869 |
prep |
of,down-regulation |
R15319 |
T17871 |
T17873 |
amod |
GATA-3,phosphorylation |
R15320 |
T17872 |
T17873 |
compound |
serine,phosphorylation |
R15321 |
T17873 |
T17870 |
pobj |
phosphorylation,of |
R15322 |
T17874 |
T17865 |
punct |
.,associated |
R15323 |
T17875 |
T17876 |
punct |
(,A |
R15324 |
T17876 |
T17880 |
nmod |
A,analysis |
R15325 |
T17877 |
T17876 |
punct |
),A |
R15326 |
T17878 |
T17880 |
amod |
Western,analysis |
R15327 |
T17879 |
T17880 |
compound |
blot,analysis |
R15328 |
T17880 |
T17881 |
nsubj |
analysis,shows |
R15329 |
T17881 |
T17881 |
ROOT |
shows,shows |
R15330 |
T17882 |
T17894 |
mark |
that,reduced |
R15331 |
T17883 |
T17888 |
nmod |
FP,M |
R15332 |
T17884 |
T17886 |
punct |
(,− |
R15333 |
T17885 |
T17886 |
nummod |
10,− |
R15334 |
T17886 |
T17883 |
appos |
−,FP |
R15335 |
T17887 |
T17888 |
nummod |
8,M |
R15336 |
T17888 |
T17894 |
nsubj |
M,reduced |
R15337 |
T17889 |
T17888 |
punct |
",",M |
R15338 |
T17890 |
T17891 |
nummod |
30,min |
R15339 |
T17891 |
T17888 |
appos |
min,M |
R15340 |
T17892 |
T17891 |
punct |
),min |
R15341 |
T17893 |
T17894 |
nsubj |
treatment,reduced |
R15342 |
T17894 |
T17881 |
ccomp |
reduced,shows |
R15343 |
T17895 |
T17896 |
amod |
dual,phosphorylation |
R15344 |
T17896 |
T17894 |
dobj |
phosphorylation,reduced |
R15345 |
T17897 |
T17898 |
punct |
(,threonine-180 |
R15346 |
T17898 |
T17896 |
appos |
threonine-180,phosphorylation |
R15347 |
T17899 |
T17898 |
cc |
and,threonine-180 |
R15348 |
T17900 |
T17898 |
conj |
tyrosine-182,threonine-180 |
R15349 |
T17901 |
T17898 |
punct |
),threonine-180 |
R15350 |
T17902 |
T17896 |
prep |
of,phosphorylation |
R15351 |
T17903 |
T17904 |
nummod |
p38,MAPK |
R15352 |
T17904 |
T17902 |
pobj |
MAPK,of |
R15353 |
T17905 |
T17904 |
prep |
in,MAPK |
R15354 |
T17906 |
T17907 |
compound |
anti-CD3,/ |
R15355 |
T17907 |
T17905 |
pobj |
/,in |
R15356 |
T17908 |
T17907 |
nummod |
CD28,/ |
R15357 |
T17909 |
T17911 |
amod |
co-stimulated,cells |
R15358 |
T17910 |
T17911 |
amod |
HuT-78,cells |
R15359 |
T17911 |
T17896 |
appos |
cells,phosphorylation |
R15360 |
T17912 |
T17881 |
punct |
.,shows |
R15361 |
T17913 |
T17917 |
punct |
(,course |
R15362 |
T17914 |
T17917 |
compound |
B,course |
R15363 |
T17915 |
T17916 |
punct |
),Time |
R15364 |
T17916 |
T17917 |
compound |
Time,course |
R15365 |
T17917 |
T17917 |
ROOT |
course,course |
R15366 |
T17918 |
T17917 |
prep |
of,course |
R15367 |
T17919 |
T17920 |
det |
the,effect |
R15368 |
T17920 |
T17918 |
pobj |
effect,of |
R15369 |
T17921 |
T17920 |
prep |
of,effect |
R15370 |
T17922 |
T17921 |
pobj |
FP,of |
R15371 |
T17923 |
T17922 |
punct |
(,FP |
R15372 |
T17924 |
T17926 |
quantmod |
10,8 |
R15373 |
T17925 |
T17926 |
quantmod |
−,8 |
R15374 |
T17926 |
T17927 |
npadvmod |
8,M |
R15375 |
T17927 |
T17922 |
appos |
M,FP |
R15376 |
T17928 |
T17922 |
punct |
),FP |
R15377 |
T17929 |
T17920 |
prep |
on,effect |
R15378 |
T17930 |
T17929 |
pobj |
phosphorylation,on |
R15379 |
T17931 |
T17930 |
prep |
of,phosphorylation |
R15380 |
T17932 |
T17934 |
amod |
activated,factor |
R15381 |
T17933 |
T17934 |
compound |
transcription,factor |
R15382 |
T17934 |
T17931 |
pobj |
factor,of |
R15383 |
T17935 |
T17934 |
nummod |
2,factor |
R15384 |
T17936 |
T17937 |
punct |
(,ATF-2 |
R15385 |
T17937 |
T17934 |
appos |
ATF-2,factor |
R15386 |
T17938 |
T17937 |
punct |
),ATF-2 |
R15387 |
T17939 |
T17937 |
punct |
",",ATF-2 |
R15388 |
T17940 |
T17941 |
det |
a,measure |
R15389 |
T17941 |
T17937 |
appos |
measure,ATF-2 |
R15390 |
T17942 |
T17941 |
prep |
of,measure |
R15391 |
T17943 |
T17945 |
nummod |
p38,activity |
R15392 |
T17944 |
T17945 |
compound |
MAPK,activity |
R15393 |
T17945 |
T17942 |
pobj |
activity,of |
R15394 |
T17946 |
T17917 |
punct |
.,course |
R15395 |
T17947 |
T17948 |
punct |
(,C |
R15396 |
T17948 |
T17951 |
nmod |
C,inhibition |
R15397 |
T17949 |
T17948 |
punct |
),C |
R15398 |
T17950 |
T17951 |
amod |
FP-induced,inhibition |
R15399 |
T17951 |
T17957 |
nsubjpass |
inhibition,associated |
R15400 |
T17952 |
T17951 |
prep |
of,inhibition |
R15401 |
T17953 |
T17955 |
nummod |
p38,activity |
R15402 |
T17954 |
T17955 |
compound |
MAPK,activity |
R15403 |
T17955 |
T17952 |
pobj |
activity,of |
R15404 |
T17956 |
T17957 |
auxpass |
is,associated |
R15405 |
T17957 |
T17957 |
ROOT |
associated,associated |
R15406 |
T17958 |
T17957 |
prep |
with,associated |
R15407 |
T17959 |
T17960 |
det |
the,decrease |
R15408 |
T17960 |
T17958 |
pobj |
decrease,with |
R15409 |
T17961 |
T17960 |
prep |
of,decrease |
R15410 |
T17962 |
T17966 |
dep |
anti-CD3,induced |
R15411 |
T17963 |
T17966 |
dep |
/,induced |
R15412 |
T17964 |
T17965 |
nummod |
CD28,co-stimulation |
R15413 |
T17965 |
T17963 |
appos |
co-stimulation,/ |
R15414 |
T17966 |
T17957 |
advcl |
induced,associated |
R15415 |
T17967 |
T17968 |
amod |
serine,phosphorylation |
R15416 |
T17968 |
T17966 |
dobj |
phosphorylation,induced |
R15417 |
T17969 |
T17970 |
punct |
(,P-Ser |
R15418 |
T17970 |
T17968 |
appos |
P-Ser,phosphorylation |
R15419 |
T17971 |
T17970 |
punct |
),P-Ser |
R15420 |
T17972 |
T17968 |
prep |
of,phosphorylation |
R15421 |
T17973 |
T17972 |
pobj |
GATA-3,of |
R15422 |
T17974 |
T17966 |
punct |
.,induced |
R15423 |
T17975 |
T17988 |
prep |
For,shown |
R15424 |
T17976 |
T17977 |
punct |
(,A |
R15425 |
T17977 |
T17978 |
det |
A,C |
R15426 |
T17978 |
T17975 |
pobj |
C,For |
R15427 |
T17979 |
T17978 |
punct |
),C |
R15428 |
T17980 |
T17988 |
punct |
",",shown |
R15429 |
T17981 |
T17988 |
nsubjpass |
quantification,shown |
R15430 |
T17982 |
T17981 |
prep |
of,quantification |
R15431 |
T17983 |
T17985 |
det |
the,data |
R15432 |
T17984 |
T17985 |
compound |
densitometry,data |
R15433 |
T17985 |
T17982 |
pobj |
data,of |
R15434 |
T17986 |
T17988 |
auxpass |
is,shown |
R15435 |
T17987 |
T17988 |
advmod |
also,shown |
R15436 |
T17988 |
T17988 |
ROOT |
shown,shown |
R15437 |
T17989 |
T17988 |
punct |
.,shown |
R15438 |
T17990 |
T17991 |
det |
Each,bar |
R15439 |
T17991 |
T17992 |
nsubj |
bar,represents |
R15440 |
T17992 |
T17992 |
ROOT |
represents,represents |
R15441 |
T17993 |
T17995 |
amod |
mean,SEM |
R15442 |
T17994 |
T17995 |
compound |
±,SEM |
R15443 |
T17995 |
T17992 |
dobj |
SEM,represents |
R15444 |
T17996 |
T17995 |
prep |
of,SEM |
R15445 |
T17997 |
T17998 |
advmod |
at,least |
R15446 |
T17998 |
T17999 |
advmod |
least,three |
R15447 |
T17999 |
T18001 |
nummod |
three,experiments |
R15448 |
T18000 |
T18001 |
amod |
independent,experiments |
R15449 |
T18001 |
T17996 |
pobj |
experiments,of |
R15450 |
T18002 |
T17992 |
punct |
.,represents |
R15451 |
T18003 |
T18005 |
dep |
###,< |
R15452 |
T18004 |
T18005 |
compound |
p,< |
R15453 |
T18005 |
T18005 |
ROOT |
<,< |
R15454 |
T18006 |
T18015 |
nsubj |
0.001,compared |
R15455 |
T18007 |
T18015 |
prep |
compared,compared |
R15456 |
T18008 |
T18009 |
aux |
to,control |
R15457 |
T18009 |
T18007 |
xcomp |
control,compared |
R15458 |
T18010 |
T18015 |
punct |
",",compared |
R15459 |
T18011 |
T18013 |
nmod |
***,< |
R15460 |
T18012 |
T18013 |
nmod |
p,< |
R15461 |
T18013 |
T18014 |
nmod |
<,0.001 |
R15462 |
T18014 |
T18015 |
nsubj |
0.001,compared |
R15463 |
T18015 |
T18015 |
ROOT |
compared,compared |
R15464 |
T18016 |
T18015 |
prep |
to,compared |
R15465 |
T18017 |
T18016 |
pobj |
αCD3,to |
R15466 |
T18018 |
T18020 |
amod |
/,cells |
R15467 |
T18019 |
T18020 |
amod |
CD28-stimulated,cells |
R15468 |
T18020 |
T18017 |
dobj |
cells,αCD3 |
R15469 |
T18021 |
T18015 |
punct |
.,compared |
R15470 |
T18022 |
T18026 |
punct |
(,induced |
R15471 |
T18023 |
T18025 |
nmod |
D,FP |
R15472 |
T18024 |
T18025 |
punct |
),FP |
R15473 |
T18025 |
T18026 |
nsubj |
FP,induced |
R15474 |
T18026 |
T18026 |
ROOT |
induced,induced |
R15475 |
T18027 |
T18028 |
compound |
MKP-1,mRNA |
R15476 |
T18028 |
T18026 |
dobj |
mRNA,induced |
R15477 |
T18029 |
T18026 |
prep |
in,induced |
R15478 |
T18030 |
T18032 |
det |
a,manner |
R15479 |
T18031 |
T18032 |
amod |
concentration-dependent,manner |
R15480 |
T18032 |
T18029 |
pobj |
manner,in |
R15481 |
T18033 |
T18026 |
punct |
.,induced |
R15482 |
T18034 |
T18035 |
det |
All,results |
R15483 |
T18035 |
T18036 |
nsubj |
results,are |
R15484 |
T18036 |
T18036 |
ROOT |
are,are |
R15485 |
T18037 |
T18036 |
attr |
representative,are |
R15486 |
T18038 |
T18037 |
prep |
of,representative |
R15487 |
T18039 |
T18040 |
advmod |
at,least |
R15488 |
T18040 |
T18041 |
advmod |
least,three |
R15489 |
T18041 |
T18043 |
nummod |
three,experiments |
R15490 |
T18042 |
T18043 |
amod |
independent,experiments |
R15491 |
T18043 |
T18038 |
pobj |
experiments,of |
R15492 |
T18044 |
T18043 |
cc |
and,experiments |
R15493 |
T18045 |
T18047 |
advmod |
where,expressed |
R15494 |
T18046 |
T18047 |
amod |
appropriate,expressed |
R15495 |
T18047 |
T18037 |
relcl |
expressed,representative |
R15496 |
T18048 |
T18047 |
prep |
as,expressed |
R15497 |
T18049 |
T18048 |
pobj |
means,as |
R15498 |
T18050 |
T18051 |
compound |
±,SEM |
R15499 |
T18051 |
T18054 |
dep |
SEM,p |
R15500 |
T18052 |
T18051 |
punct |
",",SEM |
R15501 |
T18053 |
T18051 |
punct |
*,SEM |
R15502 |
T18054 |
T18036 |
dep |
p,are |
R15503 |
T18055 |
T18056 |
nmod |
<,0.05 |
R15504 |
T18056 |
T18054 |
npadvmod |
0.05,p |
R15505 |
T18057 |
T18036 |
punct |
.,are |
R15506 |
T18058 |
T18062 |
punct |
(,induces |
R15507 |
T18059 |
T18061 |
nmod |
E,FP |
R15508 |
T18060 |
T18061 |
punct |
),FP |
R15509 |
T18061 |
T18062 |
nsubj |
FP,induces |
R15510 |
T18062 |
T18062 |
ROOT |
induces,induces |
R15511 |
T18063 |
T18064 |
compound |
MKP-1,mRNA |
R15512 |
T18064 |
T18062 |
dobj |
mRNA,induces |
R15513 |
T18065 |
T18062 |
prep |
in,induces |
R15514 |
T18066 |
T18068 |
det |
a,manner |
R15515 |
T18067 |
T18068 |
amod |
time-dependent,manner |
R15516 |
T18068 |
T18065 |
pobj |
manner,in |
R15517 |
T18069 |
T18062 |
punct |
.,induces |
R15518 |
T18070 |
T18071 |
nsubj |
Results,are |
R15519 |
T18071 |
T18071 |
ROOT |
are,are |
R15520 |
T18072 |
T18071 |
attr |
representative,are |
R15521 |
T18073 |
T18072 |
prep |
of,representative |
R15522 |
T18074 |
T18076 |
nummod |
two,experiments |
R15523 |
T18075 |
T18076 |
amod |
independent,experiments |
R15524 |
T18076 |
T18073 |
pobj |
experiments,of |
R15525 |
T18077 |
T18071 |
punct |
.,are |
R15526 |
T18078 |
T18079 |
det |
All,data |
R15527 |
T18079 |
T18085 |
nsubjpass |
data,analysed |
R15528 |
T18080 |
T18079 |
prep |
except,data |
R15529 |
T18081 |
T18082 |
punct |
(,E |
R15530 |
T18082 |
T18080 |
pobj |
E,except |
R15531 |
T18083 |
T18079 |
punct |
),data |
R15532 |
T18084 |
T18085 |
auxpass |
were,analysed |
R15533 |
T18085 |
T18085 |
ROOT |
analysed,analysed |
R15534 |
T18086 |
T18085 |
agent |
by,analysed |
R15535 |
T18087 |
T18086 |
pobj |
ANOVA,by |
R15536 |
T18088 |
T18085 |
prep |
followed,analysed |
R15537 |
T18089 |
T18088 |
agent |
by,followed |
R15538 |
T18090 |
T18089 |
pobj |
Newman-Keuls,by |
R15539 |
T18091 |
T18088 |
advmod |
post-test,followed |
R15540 |
T18092 |
T18085 |
punct |
.,analysed |
R15666 |
T18334 |
T18335 |
compound |
Fluticasone,propionate |
R15667 |
T18335 |
T18336 |
nsubj |
propionate,competes |
R15668 |
T18336 |
T18336 |
ROOT |
competes,competes |
R15669 |
T18337 |
T18336 |
prep |
with,competes |
R15670 |
T18338 |
T18337 |
pobj |
phospho-GATA-3,with |
R15671 |
T18339 |
T18338 |
prep |
for,phospho-GATA-3 |
R15672 |
T18340 |
T18339 |
pobj |
importin-α,for |
R15673 |
T18341 |
T18336 |
punct |
.,competes |
R15674 |
T18342 |
T18346 |
punct |
(,representation |
R15675 |
T18343 |
T18346 |
det |
A,representation |
R15676 |
T18344 |
T18346 |
punct |
),representation |
R15677 |
T18345 |
T18346 |
amod |
schematic,representation |
R15678 |
T18346 |
T18346 |
ROOT |
representation,representation |
R15679 |
T18347 |
T18346 |
prep |
of,representation |
R15680 |
T18348 |
T18353 |
det |
the,assay |
R15681 |
T18349 |
T18353 |
nmod |
in,assay |
R15682 |
T18350 |
T18353 |
amod |
vitro,assay |
R15683 |
T18351 |
T18352 |
amod |
binding,competition |
R15684 |
T18352 |
T18353 |
compound |
competition,assay |
R15685 |
T18353 |
T18347 |
pobj |
assay,of |
R15686 |
T18354 |
T18346 |
punct |
.,representation |
R15687 |
T18355 |
T18358 |
punct |
(,GR |
R15688 |
T18356 |
T18358 |
nmod |
B,GR |
R15689 |
T18357 |
T18358 |
punct |
),GR |
R15690 |
T18358 |
T18359 |
nsubj |
GR,isolated |
R15691 |
T18359 |
T18359 |
ROOT |
isolated,isolated |
R15692 |
T18360 |
T18359 |
prep |
from,isolated |
R15693 |
T18361 |
T18360 |
pobj |
FP,from |
R15694 |
T18362 |
T18361 |
punct |
(,FP |
R15695 |
T18363 |
T18364 |
nummod |
10,− |
R15696 |
T18364 |
T18361 |
appos |
−,FP |
R15697 |
T18365 |
T18366 |
nummod |
8,M |
R15698 |
T18366 |
T18364 |
appos |
M,− |
R15699 |
T18367 |
T18364 |
punct |
),− |
R15700 |
T18368 |
T18369 |
amod |
stimulated,cells |
R15701 |
T18369 |
T18370 |
nsubj |
cells,enhances |
R15702 |
T18370 |
T18370 |
ROOT |
enhances,enhances |
R15703 |
T18371 |
T18370 |
dobj |
GR,enhances |
R15704 |
T18372 |
T18373 |
nsubj |
importin-α,binding |
R15705 |
T18373 |
T18370 |
oprd |
binding,enhances |
R15706 |
T18374 |
T18373 |
prep |
in,binding |
R15707 |
T18375 |
T18376 |
det |
the,presence |
R15708 |
T18376 |
T18374 |
pobj |
presence,in |
R15709 |
T18377 |
T18378 |
punct |
(,• |
R15710 |
T18378 |
T18376 |
appos |
•,presence |
R15711 |
T18379 |
T18378 |
punct |
),• |
R15712 |
T18380 |
T18378 |
cc |
and,• |
R15713 |
T18381 |
T18378 |
conj |
absence,• |
R15714 |
T18382 |
T18383 |
punct |
(,▪ |
R15715 |
T18383 |
T18381 |
appos |
▪,absence |
R15716 |
T18384 |
T18376 |
punct |
),presence |
R15717 |
T18385 |
T18376 |
prep |
of,presence |
R15718 |
T18386 |
T18387 |
amod |
activated,GATA-3 |
R15719 |
T18387 |
T18385 |
pobj |
GATA-3,of |
R15720 |
T18388 |
T18370 |
punct |
.,enhances |
R15721 |
T18389 |
T18393 |
punct |
*,compared |
R15722 |
T18390 |
T18391 |
compound |
p,< |
R15723 |
T18391 |
T18392 |
compound |
<,0.05 |
R15724 |
T18392 |
T18393 |
nsubj |
0.05,compared |
R15725 |
T18393 |
T18393 |
ROOT |
compared,compared |
R15726 |
T18394 |
T18393 |
prep |
to,compared |
R15727 |
T18395 |
T18397 |
det |
no,GR |
R15728 |
T18396 |
T18397 |
amod |
activated,GR |
R15729 |
T18397 |
T18394 |
pobj |
GR,to |
R15730 |
T18398 |
T18393 |
punct |
.,compared |
R15731 |
T18399 |
T18400 |
punct |
(,C |
R15732 |
T18400 |
T18400 |
ROOT |
C,C |
R15733 |
T18401 |
T18400 |
punct |
),C |
R15734 |
T18402 |
T18403 |
nsubj |
GATA-3,isolated |
R15735 |
T18403 |
T18412 |
csubj |
isolated,attenuate |
R15736 |
T18404 |
T18403 |
prep |
from,isolated |
R15737 |
T18405 |
T18406 |
compound |
anti-CD3,/ |
R15738 |
T18406 |
T18408 |
npadvmod |
/,stimulated |
R15739 |
T18407 |
T18406 |
nummod |
CD28,/ |
R15740 |
T18408 |
T18409 |
amod |
stimulated,cells |
R15741 |
T18409 |
T18404 |
pobj |
cells,from |
R15742 |
T18410 |
T18412 |
aux |
does,attenuate |
R15743 |
T18411 |
T18412 |
neg |
not,attenuate |
R15744 |
T18412 |
T18412 |
ROOT |
attenuate,attenuate |
R15745 |
T18413 |
T18412 |
dobj |
GR,attenuate |
R15746 |
T18414 |
T18415 |
amod |
importin-α,association |
R15747 |
T18415 |
T18413 |
appos |
association,GR |
R15748 |
T18416 |
T18412 |
punct |
.,attenuate |
R15749 |
T18417 |
T18417 |
ROOT |
*,* |
R15750 |
T18418 |
T18419 |
compound |
p,< |
R15751 |
T18419 |
T18420 |
compound |
<,0.05 |
R15752 |
T18420 |
T18421 |
nsubj |
0.05,compared |
R15753 |
T18421 |
T18421 |
ROOT |
compared,compared |
R15754 |
T18422 |
T18423 |
aux |
to,control |
R15755 |
T18423 |
T18421 |
xcomp |
control,compared |
R15756 |
T18424 |
T18421 |
punct |
.,compared |
R15757 |
T18425 |
T18430 |
punct |
(,blocks |
R15758 |
T18426 |
T18429 |
compound |
D,GR |
R15759 |
T18427 |
T18428 |
punct |
),Activated |
R15760 |
T18428 |
T18429 |
compound |
Activated,GR |
R15761 |
T18429 |
T18430 |
nsubj |
GR,blocks |
R15762 |
T18430 |
T18430 |
ROOT |
blocks,blocks |
R15763 |
T18431 |
T18432 |
det |
the,ability |
R15764 |
T18432 |
T18430 |
dobj |
ability,blocks |
R15765 |
T18433 |
T18432 |
prep |
of,ability |
R15766 |
T18434 |
T18435 |
amod |
purified,phospho-GATA-3 |
R15767 |
T18435 |
T18436 |
amod |
phospho-GATA-3,isolated |
R15768 |
T18436 |
T18433 |
pobj |
isolated,of |
R15769 |
T18437 |
T18436 |
prep |
from,isolated |
R15770 |
T18438 |
T18439 |
compound |
anti-CD3,/ |
R15771 |
T18439 |
T18440 |
compound |
/,CD28 |
R15772 |
T18440 |
T18437 |
pobj |
CD28,from |
R15773 |
T18441 |
T18442 |
amod |
stimulated,cells |
R15774 |
T18442 |
T18430 |
dobj |
cells,blocks |
R15775 |
T18443 |
T18442 |
acl |
interacting,cells |
R15776 |
T18444 |
T18443 |
prep |
with,interacting |
R15777 |
T18445 |
T18446 |
amod |
immobilised,importin-α |
R15778 |
T18446 |
T18444 |
pobj |
importin-α,with |
R15779 |
T18447 |
T18443 |
prep |
in,interacting |
R15780 |
T18448 |
T18452 |
det |
an,assay |
R15781 |
T18449 |
T18452 |
nmod |
in,assay |
R15782 |
T18450 |
T18452 |
amod |
vitro,assay |
R15783 |
T18451 |
T18452 |
amod |
binding,assay |
R15784 |
T18452 |
T18447 |
pobj |
assay,in |
R15785 |
T18453 |
T18430 |
punct |
.,blocks |
R15786 |
T18454 |
T18461 |
punct |
*,isolated |
R15787 |
T18455 |
T18456 |
compound |
p,< |
R15788 |
T18456 |
T18457 |
compound |
<,0.05 |
R15789 |
T18457 |
T18461 |
nsubjpass |
0.05,isolated |
R15790 |
T18458 |
T18461 |
prep |
compared,isolated |
R15791 |
T18459 |
T18461 |
aux |
to,isolated |
R15792 |
T18460 |
T18461 |
nsubj |
GATA-3,isolated |
R15793 |
T18461 |
T18461 |
ROOT |
isolated,isolated |
R15794 |
T18462 |
T18461 |
prep |
from,isolated |
R15795 |
T18463 |
T18464 |
amod |
unstimulated,cells |
R15796 |
T18464 |
T18462 |
pobj |
cells,from |
R15797 |
T18465 |
T18461 |
punct |
.,isolated |
R15798 |
T18466 |
T18468 |
amod |
# p,0.05 |
R15799 |
T18467 |
T18468 |
compound |
<,0.05 |
R15800 |
T18468 |
T18469 |
nsubj |
0.05,compared |
R15801 |
T18469 |
T18469 |
ROOT |
compared,compared |
R15802 |
T18470 |
T18471 |
aux |
to,stimulated |
R15803 |
T18471 |
T18469 |
xcomp |
stimulated,compared |
R15804 |
T18472 |
T18473 |
advmod |
GATA-3-importin,binding |
R15805 |
T18473 |
T18471 |
oprd |
binding,stimulated |
R15806 |
T18474 |
T18469 |
punct |
.,compared |
R15807 |
T18475 |
T18476 |
punct |
(,E |
R15808 |
T18476 |
T18476 |
ROOT |
E,E |
R15809 |
T18477 |
T18476 |
punct |
),E |
R15810 |
T18478 |
T18479 |
det |
The,effect |
R15811 |
T18479 |
T18497 |
nsubj |
effect,was |
R15812 |
T18480 |
T18479 |
prep |
of,effect |
R15813 |
T18481 |
T18483 |
amod |
activated,• |
R15814 |
T18482 |
T18483 |
punct |
(,• |
R15815 |
T18483 |
T18480 |
pobj |
•,of |
R15816 |
T18484 |
T18483 |
punct |
),• |
R15817 |
T18485 |
T18483 |
cc |
versus,• |
R15818 |
T18486 |
T18483 |
conj |
unstimulated,• |
R15819 |
T18487 |
T18488 |
punct |
(,○ |
R15820 |
T18488 |
T18486 |
appos |
○,unstimulated |
R15821 |
T18489 |
T18483 |
punct |
),• |
R15822 |
T18490 |
T18479 |
conj |
GR,effect |
R15823 |
T18491 |
T18490 |
prep |
on,GR |
R15824 |
T18492 |
T18491 |
pobj |
attenuation,on |
R15825 |
T18493 |
T18492 |
prep |
of,attenuation |
R15826 |
T18494 |
T18493 |
pobj |
GATA-3,of |
R15827 |
T18495 |
T18496 |
amod |
importin-α,association |
R15828 |
T18496 |
T18497 |
nsubj |
association,was |
R15829 |
T18497 |
T18497 |
ROOT |
was,was |
R15830 |
T18498 |
T18497 |
acomp |
concentration-dependent,was |
R15831 |
T18499 |
T18497 |
punct |
.,was |
R15832 |
T18500 |
T18503 |
punct |
*,0.05 |
R15833 |
T18501 |
T18502 |
compound |
p,< |
R15834 |
T18502 |
T18503 |
compound |
<,0.05 |
R15835 |
T18503 |
T18503 |
ROOT |
0.05,0.05 |
R15836 |
T18504 |
T18508 |
punct |
",",0.01 |
R15837 |
T18505 |
T18508 |
amod |
**,0.01 |
R15838 |
T18506 |
T18508 |
compound |
p,0.01 |
R15839 |
T18507 |
T18508 |
compound |
<,0.01 |
R15840 |
T18508 |
T18503 |
appos |
0.01,0.05 |
R15841 |
T18509 |
T18508 |
prep |
between,0.01 |
R15842 |
T18510 |
T18509 |
pobj |
groups,between |
R15843 |
T18511 |
T18503 |
punct |
.,0.05 |
R15844 |
T18512 |
T18513 |
det |
All,results |
R15845 |
T18513 |
T18515 |
nsubjpass |
results,expressed |
R15846 |
T18514 |
T18515 |
auxpass |
are,expressed |
R15847 |
T18515 |
T18515 |
ROOT |
expressed,expressed |
R15848 |
T18516 |
T18515 |
prep |
as,expressed |
R15849 |
T18517 |
T18519 |
amod |
mean,SEM |
R15850 |
T18518 |
T18519 |
compound |
±,SEM |
R15851 |
T18519 |
T18516 |
pobj |
SEM,as |
R15852 |
T18520 |
T18519 |
prep |
of,SEM |
R15853 |
T18521 |
T18523 |
nummod |
three,experiments |
R15854 |
T18522 |
T18523 |
amod |
independent,experiments |
R15855 |
T18523 |
T18520 |
pobj |
experiments,of |
R15856 |
T18524 |
T18523 |
cc |
and,experiments |
R15857 |
T18525 |
T18515 |
advcl |
analysed,expressed |
R15858 |
T18526 |
T18525 |
agent |
by,analysed |
R15859 |
T18527 |
T18526 |
pobj |
ANOVA,by |
R15860 |
T18528 |
T18525 |
acl |
followed,analysed |
R15861 |
T18529 |
T18528 |
agent |
by,followed |
R15862 |
T18530 |
T18529 |
pobj |
Newman-Keuls,by |
R15863 |
T18531 |
T18515 |
conj |
post-test,expressed |
R15864 |
T18532 |
T18515 |
punct |
.,expressed |
R16160 |
T18930 |
T18931 |
compound |
Fluticasone,propionate |
R16161 |
T18931 |
T18934 |
nsubj |
propionate,affect |
R16162 |
T18932 |
T18934 |
aux |
does,affect |
R16163 |
T18933 |
T18934 |
neg |
not,affect |
R16164 |
T18934 |
T18934 |
ROOT |
affect,affect |
R16165 |
T18935 |
T18937 |
amod |
GATA-3,export |
R16166 |
T18936 |
T18937 |
amod |
nuclear,export |
R16167 |
T18937 |
T18934 |
dobj |
export,affect |
R16168 |
T18938 |
T18934 |
punct |
.,affect |
R16169 |
T18939 |
T18940 |
punct |
(,A |
R16170 |
T18940 |
T18944 |
nmod |
A,analysis |
R16171 |
T18941 |
T18940 |
punct |
),A |
R16172 |
T18942 |
T18944 |
amod |
Western,analysis |
R16173 |
T18943 |
T18944 |
compound |
blot,analysis |
R16174 |
T18944 |
T18975 |
nsubj |
analysis,stimulated |
R16175 |
T18945 |
T18944 |
acl |
showing,analysis |
R16176 |
T18946 |
T18959 |
mark |
that,affect |
R16177 |
T18947 |
T18959 |
det |
the,affect |
R16178 |
T18948 |
T18950 |
amod |
nuclear,inhibitor |
R16179 |
T18949 |
T18950 |
compound |
export,inhibitor |
R16180 |
T18950 |
T18959 |
nsubj |
inhibitor,affect |
R16181 |
T18951 |
T18952 |
compound |
leptomycin,B |
R16182 |
T18952 |
T18950 |
appos |
B,inhibitor |
R16183 |
T18953 |
T18954 |
punct |
(,2 |
R16184 |
T18954 |
T18955 |
nummod |
2,nM |
R16185 |
T18955 |
T18952 |
appos |
nM,B |
R16186 |
T18956 |
T18952 |
punct |
),B |
R16187 |
T18957 |
T18959 |
aux |
does,affect |
R16188 |
T18958 |
T18959 |
neg |
not,affect |
R16189 |
T18959 |
T18945 |
ccomp |
affect,showing |
R16190 |
T18960 |
T18961 |
det |
the,ability |
R16191 |
T18961 |
T18959 |
dobj |
ability,affect |
R16192 |
T18962 |
T18961 |
prep |
of,ability |
R16193 |
T18963 |
T18962 |
pobj |
FP,of |
R16194 |
T18964 |
T18963 |
punct |
(,FP |
R16195 |
T18965 |
T18966 |
nummod |
10,− |
R16196 |
T18966 |
T18963 |
appos |
−,FP |
R16197 |
T18967 |
T18968 |
nummod |
8,M |
R16198 |
T18968 |
T18966 |
appos |
M,− |
R16199 |
T18969 |
T18966 |
punct |
),− |
R16200 |
T18970 |
T18971 |
aux |
to,prevent |
R16201 |
T18971 |
T18961 |
acl |
prevent,ability |
R16202 |
T18972 |
T18973 |
compound |
anti-CD3,/ |
R16203 |
T18973 |
T18971 |
dobj |
/,prevent |
R16204 |
T18974 |
T18973 |
nummod |
CD28,/ |
R16205 |
T18975 |
T18975 |
ROOT |
stimulated,stimulated |
R16206 |
T18976 |
T18978 |
amod |
GATA-3,localization |
R16207 |
T18977 |
T18978 |
amod |
nuclear,localization |
R16208 |
T18978 |
T18975 |
dobj |
localization,stimulated |
R16209 |
T18979 |
T18978 |
acl |
measured,localization |
R16210 |
T18980 |
T18979 |
prep |
at,measured |
R16211 |
T18981 |
T18982 |
nummod |
60,min |
R16212 |
T18982 |
T18980 |
pobj |
min,at |
R16213 |
T18983 |
T18975 |
punct |
.,stimulated |
R16214 |
T18984 |
T18986 |
compound |
***,< |
R16215 |
T18985 |
T18986 |
compound |
p,< |
R16216 |
T18986 |
T18988 |
nsubj |
<,compared |
R16217 |
T18987 |
T18986 |
nummod |
0.001,< |
R16218 |
T18988 |
T18997 |
prep |
compared,compared |
R16219 |
T18989 |
T18988 |
prep |
to,compared |
R16220 |
T18990 |
T18991 |
amod |
unstimulated,cells |
R16221 |
T18991 |
T18989 |
pobj |
cells,to |
R16222 |
T18992 |
T18997 |
punct |
",",compared |
R16223 |
T18993 |
T18995 |
nmod |
###,< |
R16224 |
T18994 |
T18995 |
nmod |
p,< |
R16225 |
T18995 |
T18996 |
nmod |
<,0.001 |
R16226 |
T18996 |
T18997 |
nsubj |
0.001,compared |
R16227 |
T18997 |
T18997 |
ROOT |
compared,compared |
R16228 |
T18998 |
T18997 |
prep |
to,compared |
R16229 |
T18999 |
T19002 |
dep |
anti-CD3,stimulated |
R16230 |
T19000 |
T18999 |
dobj |
/,anti-CD3 |
R16231 |
T19001 |
T19000 |
nummod |
CD28,/ |
R16232 |
T19002 |
T18998 |
pcomp |
stimulated,to |
R16233 |
T19003 |
T19002 |
dobj |
cells,stimulated |
R16234 |
T19004 |
T19002 |
punct |
.,stimulated |
R16235 |
T19005 |
T19010 |
punct |
(,analysis |
R16236 |
T19006 |
T19010 |
nmod |
B,analysis |
R16237 |
T19007 |
T19010 |
punct |
),analysis |
R16238 |
T19008 |
T19010 |
amod |
Western,analysis |
R16239 |
T19009 |
T19010 |
compound |
blot,analysis |
R16240 |
T19010 |
T19010 |
ROOT |
analysis,analysis |
R16241 |
T19011 |
T19010 |
acl |
showing,analysis |
R16242 |
T19012 |
T19022 |
mark |
that,affect |
R16243 |
T19013 |
T19022 |
nsubj |
FP,affect |
R16244 |
T19014 |
T19016 |
punct |
(,− |
R16245 |
T19015 |
T19016 |
nummod |
10,− |
R16246 |
T19016 |
T19022 |
nsubj |
−,affect |
R16247 |
T19017 |
T19016 |
nummod |
8,− |
R16248 |
T19018 |
T19016 |
appos |
M,− |
R16249 |
T19019 |
T19016 |
punct |
),− |
R16250 |
T19020 |
T19022 |
aux |
does,affect |
R16251 |
T19021 |
T19022 |
neg |
not,affect |
R16252 |
T19022 |
T19011 |
ccomp |
affect,showing |
R16253 |
T19023 |
T19025 |
amod |
whole-cell,degradation |
R16254 |
T19024 |
T19025 |
amod |
GATA-3,degradation |
R16255 |
T19025 |
T19022 |
dobj |
degradation,affect |
R16256 |
T19026 |
T19025 |
prep |
over,degradation |
R16257 |
T19027 |
T19028 |
nummod |
17,h. |
R16258 |
T19028 |
T19026 |
pobj |
h.,over |
R16259 |
T19029 |
T19030 |
punct |
(,C |
R16260 |
T19030 |
T19028 |
appos |
C,h. |
R16261 |
T19031 |
T19030 |
punct |
),C |
R16262 |
T19032 |
T19033 |
amod |
GFP-tagged,GATA-3 |
R16263 |
T19033 |
T19034 |
nsubj |
GATA-3,is |
R16264 |
T19034 |
T19034 |
ROOT |
is,is |
R16265 |
T19035 |
T19034 |
acomp |
overexpressed,is |
R16266 |
T19036 |
T19035 |
cc |
and,overexpressed |
R16267 |
T19037 |
T19035 |
conj |
cells,overexpressed |
R16268 |
T19038 |
T19037 |
acl |
stimulated,cells |
R16269 |
T19039 |
T19041 |
punct |
(,j |
R16270 |
T19040 |
T19041 |
nmod |
b,j |
R16271 |
T19041 |
T19038 |
dobj |
j,stimulated |
R16272 |
T19042 |
T19041 |
punct |
),j |
R16273 |
T19043 |
T19038 |
cc |
or,stimulated |
R16274 |
T19044 |
T19045 |
neg |
not,( |
R16275 |
T19045 |
T19046 |
punct |
(,a |
R16276 |
T19046 |
T19037 |
appos |
a,cells |
R16277 |
T19047 |
T19046 |
punct |
),a |
R16278 |
T19048 |
T19046 |
prep |
with,a |
R16279 |
T19049 |
T19050 |
amod |
anti-CD3,/ |
R16280 |
T19050 |
T19051 |
compound |
/,CD28 |
R16281 |
T19051 |
T19048 |
pobj |
CD28,with |
R16282 |
T19052 |
T19034 |
punct |
.,is |
R16283 |
T19053 |
T19054 |
det |
The,effect |
R16284 |
T19054 |
T19079 |
nsubjpass |
effect,shown |
R16285 |
T19055 |
T19054 |
prep |
of,effect |
R16286 |
T19056 |
T19055 |
pcomp |
treating,of |
R16287 |
T19057 |
T19056 |
dobj |
cells,treating |
R16288 |
T19058 |
T19056 |
prep |
with,treating |
R16289 |
T19059 |
T19058 |
pobj |
FP,with |
R16290 |
T19060 |
T19062 |
punct |
(,− |
R16291 |
T19061 |
T19062 |
nummod |
10,− |
R16292 |
T19062 |
T19079 |
npadvmod |
−,shown |
R16293 |
T19063 |
T19062 |
nummod |
8,− |
R16294 |
T19064 |
T19079 |
npadvmod |
M,shown |
R16295 |
T19065 |
T19079 |
punct |
",",shown |
R16296 |
T19066 |
T19079 |
nsubjpass |
f,shown |
R16297 |
T19067 |
T19066 |
appos |
j,f |
R16298 |
T19068 |
T19066 |
punct |
),f |
R16299 |
T19069 |
T19066 |
prep |
after,f |
R16300 |
T19070 |
T19072 |
nummod |
30,stimulation |
R16301 |
T19071 |
T19072 |
compound |
min,stimulation |
R16302 |
T19072 |
T19069 |
pobj |
stimulation,after |
R16303 |
T19073 |
T19072 |
prep |
with,stimulation |
R16304 |
T19074 |
T19075 |
amod |
anti-CD3,/ |
R16305 |
T19075 |
T19076 |
compound |
/,CD28 |
R16306 |
T19076 |
T19073 |
pobj |
CD28,with |
R16307 |
T19077 |
T19079 |
auxpass |
is,shown |
R16308 |
T19078 |
T19079 |
advmod |
also,shown |
R16309 |
T19079 |
T19079 |
ROOT |
shown,shown |
R16310 |
T19080 |
T19079 |
punct |
.,shown |
R16311 |
T19081 |
T19084 |
punct |
(,FP |
R16312 |
T19082 |
T19084 |
nmod |
D,FP |
R16313 |
T19083 |
T19084 |
punct |
),FP |
R16314 |
T19084 |
T19093 |
nsubj |
FP,prevent |
R16315 |
T19085 |
T19087 |
punct |
(,− |
R16316 |
T19086 |
T19087 |
nummod |
10,− |
R16317 |
T19087 |
T19093 |
nsubj |
−,prevent |
R16318 |
T19088 |
T19087 |
nummod |
8,− |
R16319 |
T19089 |
T19087 |
appos |
M,− |
R16320 |
T19090 |
T19087 |
punct |
),− |
R16321 |
T19091 |
T19093 |
aux |
does,prevent |
R16322 |
T19092 |
T19093 |
neg |
not,prevent |
R16323 |
T19093 |
T19097 |
ccomp |
prevent,stimulated |
R16324 |
T19094 |
T19095 |
compound |
anti-CD3,/ |
R16325 |
T19095 |
T19093 |
dobj |
/,prevent |
R16326 |
T19096 |
T19095 |
nummod |
CD28,/ |
R16327 |
T19097 |
T19097 |
ROOT |
stimulated,stimulated |
R16328 |
T19098 |
T19100 |
nummod |
p65,translocation |
R16329 |
T19099 |
T19100 |
amod |
nuclear,translocation |
R16330 |
T19100 |
T19097 |
dobj |
translocation,stimulated |
R16331 |
T19101 |
T19097 |
prep |
at,stimulated |
R16332 |
T19102 |
T19103 |
nummod |
60,min |
R16333 |
T19103 |
T19101 |
pobj |
min,at |
R16334 |
T19104 |
T19103 |
prep |
after,min |
R16335 |
T19105 |
T19104 |
pobj |
stimulation,after |
R16336 |
T19106 |
T19097 |
punct |
.,stimulated |
R16337 |
T19107 |
T19111 |
dep |
**,compared |
R16338 |
T19108 |
T19111 |
nsubj |
p,compared |
R16339 |
T19109 |
T19110 |
nmod |
<,0.01 |
R16340 |
T19110 |
T19108 |
npadvmod |
0.01,p |
R16341 |
T19111 |
T19111 |
ROOT |
compared,compared |
R16342 |
T19112 |
T19111 |
prep |
to,compared |
R16343 |
T19113 |
T19114 |
amod |
unstimulated,cells |
R16344 |
T19114 |
T19112 |
pobj |
cells,to |
R16345 |
T19115 |
T19111 |
punct |
.,compared |
R16346 |
T19116 |
T19117 |
det |
All,results |
R16347 |
T19117 |
T19118 |
nsubj |
results,are |
R16348 |
T19118 |
T19118 |
ROOT |
are,are |
R16349 |
T19119 |
T19118 |
attr |
representative,are |
R16350 |
T19120 |
T19119 |
prep |
of,representative |
R16351 |
T19121 |
T19122 |
advmod |
at,least |
R16352 |
T19122 |
T19123 |
advmod |
least,four |
R16353 |
T19123 |
T19125 |
nummod |
four,experiments |
R16354 |
T19124 |
T19125 |
amod |
independent,experiments |
R16355 |
T19125 |
T19120 |
pobj |
experiments,of |
R16356 |
T19126 |
T19118 |
cc |
and,are |
R16357 |
T19127 |
T19128 |
auxpass |
are,shown |
R16358 |
T19128 |
T19118 |
conj |
shown,are |
R16359 |
T19129 |
T19128 |
prep |
as,shown |
R16360 |
T19130 |
T19132 |
amod |
mean,SEM |
R16361 |
T19131 |
T19132 |
compound |
±,SEM |
R16362 |
T19132 |
T19129 |
pobj |
SEM,as |
R16363 |
T19133 |
T19118 |
punct |
.,are |
R16364 |
T19134 |
T19136 |
nsubjpass |
Results,analysed |
R16365 |
T19135 |
T19136 |
auxpass |
were,analysed |
R16366 |
T19136 |
T19136 |
ROOT |
analysed,analysed |
R16367 |
T19137 |
T19136 |
agent |
by,analysed |
R16368 |
T19138 |
T19137 |
pobj |
ANOVA,by |
R16369 |
T19139 |
T19136 |
acl |
followed,analysed |
R16370 |
T19140 |
T19139 |
agent |
by,followed |
R16371 |
T19141 |
T19142 |
compound |
Newman-Keuls,test |
R16372 |
T19142 |
T19140 |
pobj |
test,by |
R16373 |
T19143 |
T19136 |
punct |
.,analysed |
R16592 |
T19430 |
T19431 |
compound |
Fluticasone,propionate |
R16593 |
T19431 |
T19432 |
nsubj |
propionate,impairs |
R16594 |
T19432 |
T19432 |
ROOT |
impairs,impairs |
R16595 |
T19433 |
T19434 |
amod |
GATA-3,interaction |
R16596 |
T19434 |
T19432 |
dobj |
interaction,impairs |
R16597 |
T19435 |
T19434 |
prep |
with,interaction |
R16598 |
T19436 |
T19440 |
amod |
importin-α,localization |
R16599 |
T19437 |
T19436 |
cc |
and,importin-α |
R16600 |
T19438 |
T19436 |
conj |
GATA-3,importin-α |
R16601 |
T19439 |
T19440 |
amod |
nuclear,localization |
R16602 |
T19440 |
T19435 |
pobj |
localization,with |
R16603 |
T19441 |
T19440 |
prep |
in,localization |
R16604 |
T19442 |
T19441 |
pobj |
vivo,in |
R16605 |
T19443 |
T19442 |
cc |
and,vivo |
R16606 |
T19444 |
T19445 |
dep |
ex,vivo |
R16607 |
T19445 |
T19442 |
conj |
vivo,vivo |
R16608 |
T19446 |
T19432 |
punct |
.,impairs |
R16609 |
T19447 |
T19448 |
punct |
(,A |
R16610 |
T19448 |
T19448 |
ROOT |
A,A |
R16611 |
T19449 |
T19448 |
cc |
and,A |
R16612 |
T19450 |
T19453 |
nmod |
B,analysis |
R16613 |
T19451 |
T19450 |
punct |
),B |
R16614 |
T19452 |
T19453 |
compound |
Co-immunoprecipitation,analysis |
R16615 |
T19453 |
T19465 |
nsubj |
analysis,demonstrated |
R16616 |
T19454 |
T19453 |
prep |
of,analysis |
R16617 |
T19455 |
T19454 |
pobj |
PBMCs,of |
R16618 |
T19456 |
T19455 |
prep |
from,PBMCs |
R16619 |
T19457 |
T19459 |
amod |
steroid-naïve,patients |
R16620 |
T19458 |
T19459 |
compound |
asthma,patients |
R16621 |
T19459 |
T19456 |
pobj |
patients,from |
R16622 |
T19460 |
T19459 |
acl |
treated,patients |
R16623 |
T19461 |
T19460 |
prep |
with,treated |
R16624 |
T19462 |
T19461 |
pobj |
FP,with |
R16625 |
T19463 |
T19460 |
prep |
in,treated |
R16626 |
T19464 |
T19463 |
pobj |
vitro,in |
R16627 |
T19465 |
T19448 |
conj |
demonstrated,A |
R16628 |
T19466 |
T19467 |
amod |
impaired,interaction |
R16629 |
T19467 |
T19465 |
dobj |
interaction,demonstrated |
R16630 |
T19468 |
T19467 |
prep |
between,interaction |
R16631 |
T19469 |
T19468 |
pobj |
GATA-3,between |
R16632 |
T19470 |
T19469 |
cc |
and,GATA-3 |
R16633 |
T19471 |
T19469 |
conj |
importin-α,GATA-3 |
R16634 |
T19472 |
T19465 |
conj |
measured,demonstrated |
R16635 |
T19473 |
T19472 |
prep |
at,measured |
R16636 |
T19474 |
T19475 |
nummod |
60,min |
R16637 |
T19475 |
T19473 |
pobj |
min,at |
R16638 |
T19476 |
T19465 |
punct |
.,demonstrated |
R16639 |
T19477 |
T19478 |
det |
Each,bar |
R16640 |
T19478 |
T19479 |
nsubj |
bar,represents |
R16641 |
T19479 |
T19479 |
ROOT |
represents,represents |
R16642 |
T19480 |
T19483 |
det |
the,SEM |
R16643 |
T19481 |
T19483 |
amod |
mean,SEM |
R16644 |
T19482 |
T19483 |
compound |
±,SEM |
R16645 |
T19483 |
T19479 |
dobj |
SEM,represents |
R16646 |
T19484 |
T19483 |
prep |
of,SEM |
R16647 |
T19485 |
T19486 |
advmod |
at,least |
R16648 |
T19486 |
T19487 |
advmod |
least,three |
R16649 |
T19487 |
T19489 |
nummod |
three,experiments |
R16650 |
T19488 |
T19489 |
amod |
independent,experiments |
R16651 |
T19489 |
T19484 |
pobj |
experiments,of |
R16652 |
T19490 |
T19483 |
punct |
;,SEM |
R16653 |
T19491 |
T19493 |
nmod |
***,< |
R16654 |
T19492 |
T19493 |
nmod |
p,< |
R16655 |
T19493 |
T19494 |
nmod |
<,0.001 |
R16656 |
T19494 |
T19483 |
appos |
0.001,SEM |
R16657 |
T19495 |
T19494 |
prep |
compared,0.001 |
R16658 |
T19496 |
T19495 |
prep |
with,compared |
R16659 |
T19497 |
T19496 |
pobj |
control,with |
R16660 |
T19498 |
T19499 |
mark |
as,determined |
R16661 |
T19499 |
T19494 |
advcl |
determined,0.001 |
R16662 |
T19500 |
T19499 |
agent |
by,determined |
R16663 |
T19501 |
T19502 |
compound |
ANOVA/Newman-Keuls,analysis |
R16664 |
T19502 |
T19500 |
pobj |
analysis,by |
R16665 |
T19503 |
T19479 |
punct |
.,represents |
R16666 |
T19504 |
T19505 |
punct |
(,C |
R16667 |
T19505 |
T19505 |
ROOT |
C,C |
R16668 |
T19506 |
T19505 |
cc |
and,C |
R16669 |
T19507 |
T19505 |
conj |
D,C |
R16670 |
T19508 |
T19505 |
punct |
),C |
R16671 |
T19509 |
T19510 |
compound |
Co-immunoprecipitation,analyses |
R16672 |
T19510 |
T19530 |
nsubj |
analyses,demonstrated |
R16673 |
T19511 |
T19510 |
prep |
of,analyses |
R16674 |
T19512 |
T19511 |
pobj |
PBMCs,of |
R16675 |
T19513 |
T19512 |
prep |
from,PBMCs |
R16676 |
T19514 |
T19516 |
amod |
steroid-naïve,patients |
R16677 |
T19515 |
T19516 |
compound |
asthma,patients |
R16678 |
T19516 |
T19513 |
pobj |
patients,from |
R16679 |
T19517 |
T19516 |
acl |
treated,patients |
R16680 |
T19518 |
T19517 |
prep |
with,treated |
R16681 |
T19519 |
T19520 |
amod |
inhaled,FP |
R16682 |
T19520 |
T19518 |
pobj |
FP,with |
R16683 |
T19521 |
T19520 |
punct |
(,FP |
R16684 |
T19522 |
T19523 |
nummod |
500,µg |
R16685 |
T19523 |
T19520 |
appos |
µg,FP |
R16686 |
T19524 |
T19517 |
prep |
via,treated |
R16687 |
T19525 |
T19526 |
det |
a,spacer |
R16688 |
T19526 |
T19524 |
pobj |
spacer,via |
R16689 |
T19527 |
T19517 |
punct |
),treated |
R16690 |
T19528 |
T19517 |
prep |
in,treated |
R16691 |
T19529 |
T19528 |
pobj |
vivo,in |
R16692 |
T19530 |
T19530 |
ROOT |
demonstrated,demonstrated |
R16693 |
T19531 |
T19532 |
amod |
decreased,association |
R16694 |
T19532 |
T19530 |
dobj |
association,demonstrated |
R16695 |
T19533 |
T19532 |
prep |
between,association |
R16696 |
T19534 |
T19533 |
pobj |
GATA-3,between |
R16697 |
T19535 |
T19534 |
cc |
and,GATA-3 |
R16698 |
T19536 |
T19534 |
conj |
importin-α,GATA-3 |
R16699 |
T19537 |
T19530 |
punct |
.,demonstrated |
R16700 |
T19538 |
T19540 |
det |
The,values |
R16701 |
T19539 |
T19540 |
amod |
individual,values |
R16702 |
T19540 |
T19545 |
nsubjpass |
values,presented |
R16703 |
T19541 |
T19540 |
prep |
for,values |
R16704 |
T19542 |
T19543 |
det |
each,treatment |
R16705 |
T19543 |
T19541 |
pobj |
treatment,for |
R16706 |
T19544 |
T19545 |
auxpass |
are,presented |
R16707 |
T19545 |
T19545 |
ROOT |
presented,presented |
R16708 |
T19546 |
T19545 |
advmod |
graphically,presented |
R16709 |
T19547 |
T19545 |
punct |
.,presented |
R16710 |
T19548 |
T19554 |
punct |
(,showing |
R16711 |
T19549 |
T19553 |
nmod |
E,blot |
R16712 |
T19550 |
T19549 |
punct |
),E |
R16713 |
T19551 |
T19553 |
compound |
Representative,blot |
R16714 |
T19552 |
T19553 |
compound |
Western,blot |
R16715 |
T19553 |
T19554 |
nsubj |
blot,showing |
R16716 |
T19554 |
T19554 |
ROOT |
showing,showing |
R16717 |
T19555 |
T19559 |
mark |
that,unaffected |
R16718 |
T19556 |
T19557 |
amod |
importin-α,expression |
R16719 |
T19557 |
T19559 |
nsubjpass |
expression,unaffected |
R16720 |
T19558 |
T19559 |
auxpass |
was,unaffected |
R16721 |
T19559 |
T19554 |
ccomp |
unaffected,showing |
R16722 |
T19560 |
T19559 |
prep |
by,unaffected |
R16723 |
T19561 |
T19560 |
pobj |
inhalation,by |
R16724 |
T19562 |
T19561 |
prep |
of,inhalation |
R16725 |
T19563 |
T19562 |
pobj |
FP,of |
R16726 |
T19564 |
T19554 |
punct |
.,showing |
R16727 |
T19565 |
T19566 |
nsubj |
Blot,is |
R16728 |
T19566 |
T19566 |
ROOT |
is,is |
R16729 |
T19567 |
T19566 |
attr |
representative,is |
R16730 |
T19568 |
T19567 |
prep |
of,representative |
R16731 |
T19569 |
T19568 |
pobj |
gels,of |
R16732 |
T19570 |
T19567 |
prep |
from,representative |
R16733 |
T19571 |
T19572 |
nummod |
three,participants |
R16734 |
T19572 |
T19570 |
pobj |
participants,from |
R16735 |
T19573 |
T19566 |
punct |
.,is |
R17076 |
T19983 |
T19985 |
amod |
Inhaled,propionate |
R17077 |
T19984 |
T19985 |
compound |
fluticasone,propionate |
R17078 |
T19985 |
T19986 |
nsubj |
propionate,impairs |
R17079 |
T19986 |
T19986 |
ROOT |
impairs,impairs |
R17080 |
T19987 |
T19989 |
amod |
GATA-3,localization |
R17081 |
T19988 |
T19989 |
amod |
nuclear,localization |
R17082 |
T19989 |
T19986 |
dobj |
localization,impairs |
R17083 |
T19990 |
T19989 |
prep |
in,localization |
R17084 |
T19991 |
T19990 |
pobj |
PBMCs,in |
R17085 |
T19992 |
T19986 |
punct |
.,impairs |
R17086 |
T19993 |
T19993 |
ROOT |
(,( |
R17087 |
T19994 |
T19993 |
dep |
A,( |
R17088 |
T19995 |
T19994 |
punct |
),A |
R17089 |
T19996 |
T19997 |
compound |
Representative,immunocytochemistry |
R17090 |
T19997 |
T19997 |
ROOT |
immunocytochemistry,immunocytochemistry |
R17091 |
T19998 |
T19997 |
prep |
of,immunocytochemistry |
R17092 |
T19999 |
T19998 |
pcomp |
showing,of |
R17093 |
T20000 |
T20001 |
det |
the,effect |
R17094 |
T20001 |
T19999 |
dobj |
effect,showing |
R17095 |
T20002 |
T20001 |
prep |
of,effect |
R17096 |
T20003 |
T20004 |
amod |
inhaled,FP |
R17097 |
T20004 |
T20002 |
pobj |
FP,of |
R17098 |
T20005 |
T20007 |
punct |
(,µg |
R17099 |
T20006 |
T20007 |
nummod |
500,µg |
R17100 |
T20007 |
T20004 |
appos |
µg,FP |
R17101 |
T20008 |
T20004 |
punct |
),FP |
R17102 |
T20009 |
T20001 |
prep |
on,effect |
R17103 |
T20010 |
T20014 |
nmod |
GR,localisation |
R17104 |
T20011 |
T20010 |
cc |
and,GR |
R17105 |
T20012 |
T20010 |
conj |
GATA-3,GR |
R17106 |
T20013 |
T20014 |
amod |
nuclear,localisation |
R17107 |
T20014 |
T20009 |
pobj |
localisation,on |
R17108 |
T20015 |
T19997 |
punct |
.,immunocytochemistry |
R17109 |
T20016 |
T20021 |
punct |
(,immunoreactivity |
R17110 |
T20017 |
T20021 |
nmod |
B,immunoreactivity |
R17111 |
T20018 |
T20017 |
punct |
),B |
R17112 |
T20019 |
T20020 |
compound |
Nuclear,GATA-3 |
R17113 |
T20020 |
T20021 |
compound |
GATA-3,immunoreactivity |
R17114 |
T20021 |
T20021 |
ROOT |
immunoreactivity,immunoreactivity |
R17115 |
T20022 |
T20021 |
prep |
in,immunoreactivity |
R17116 |
T20023 |
T20022 |
pobj |
PBMCs,in |
R17117 |
T20024 |
T20021 |
prep |
from,immunoreactivity |
R17118 |
T20025 |
T20028 |
nummod |
seven,patients |
R17119 |
T20026 |
T20028 |
amod |
steroid-naïve,patients |
R17120 |
T20027 |
T20028 |
compound |
asthma,patients |
R17121 |
T20028 |
T20024 |
pobj |
patients,from |
R17122 |
T20029 |
T20030 |
nummod |
2,h |
R17123 |
T20030 |
T20031 |
amod |
h,following |
R17124 |
T20031 |
T20021 |
prep |
following,immunoreactivity |
R17125 |
T20032 |
T20034 |
amod |
inhaled,treatment |
R17126 |
T20033 |
T20034 |
compound |
FP,treatment |
R17127 |
T20034 |
T20031 |
dobj |
treatment,following |
R17128 |
T20035 |
T20034 |
punct |
(,treatment |
R17129 |
T20036 |
T20039 |
nummod |
100,µg |
R17130 |
T20037 |
T20036 |
cc |
or,100 |
R17131 |
T20038 |
T20036 |
conj |
500,100 |
R17132 |
T20039 |
T20034 |
appos |
µg,treatment |
R17133 |
T20040 |
T20039 |
prep |
via,µg |
R17134 |
T20041 |
T20040 |
pobj |
spacer,via |
R17135 |
T20042 |
T20034 |
punct |
),treatment |
R17136 |
T20043 |
T20021 |
punct |
.,immunoreactivity |
R17137 |
T20044 |
T20048 |
det |
The,ranges |
R17138 |
T20045 |
T20048 |
amod |
median,ranges |
R17139 |
T20046 |
T20045 |
cc |
and,median |
R17140 |
T20047 |
T20045 |
conj |
interquartile,median |
R17141 |
T20048 |
T20053 |
nsubjpass |
ranges,presented |
R17142 |
T20049 |
T20048 |
prep |
for,ranges |
R17143 |
T20050 |
T20051 |
det |
each,treatment |
R17144 |
T20051 |
T20049 |
pobj |
treatment,for |
R17145 |
T20052 |
T20053 |
auxpass |
are,presented |
R17146 |
T20053 |
T20053 |
ROOT |
presented,presented |
R17147 |
T20054 |
T20053 |
prep |
as,presented |
R17148 |
T20055 |
T20057 |
det |
a,plot |
R17149 |
T20056 |
T20057 |
compound |
box-and-whiskers,plot |
R17150 |
T20057 |
T20054 |
pobj |
plot,as |
R17151 |
T20058 |
T20061 |
punct |
(,7 |
R17152 |
T20059 |
T20061 |
advmod |
n,7 |
R17153 |
T20060 |
T20061 |
punct |
=,7 |
R17154 |
T20061 |
T20057 |
appos |
7,plot |
R17155 |
T20062 |
T20061 |
punct |
),7 |
R17156 |
T20063 |
T20053 |
punct |
;,presented |
R17157 |
T20064 |
T20066 |
punct |
*,< |
R17158 |
T20065 |
T20066 |
compound |
p,< |
R17159 |
T20066 |
T20053 |
conj |
<,presented |
R17160 |
T20067 |
T20071 |
nummod |
0.05,test |
R17161 |
T20068 |
T20071 |
poss |
Wilcoxon,test |
R17162 |
T20069 |
T20068 |
case |
's,Wilcoxon |
R17163 |
T20070 |
T20071 |
compound |
rank,test |
R17164 |
T20071 |
T20066 |
appos |
test,< |
R17165 |
T20072 |
T20071 |
prep |
compared,test |
R17166 |
T20073 |
T20072 |
prep |
with,compared |
R17167 |
T20074 |
T20073 |
pobj |
placebo,with |
R17168 |
T20075 |
T20053 |
punct |
.,presented |
R17169 |
T20076 |
T20080 |
punct |
(,analyses |
R17170 |
T20077 |
T20080 |
compound |
C,analyses |
R17171 |
T20078 |
T20079 |
punct |
),Immunoblotting |
R17172 |
T20079 |
T20080 |
compound |
Immunoblotting,analyses |
R17173 |
T20080 |
T20083 |
nsubj |
analyses,demonstrated |
R17174 |
T20081 |
T20080 |
prep |
of,analyses |
R17175 |
T20082 |
T20081 |
pobj |
PBMCs,of |
R17176 |
T20083 |
T20083 |
ROOT |
demonstrated,demonstrated |
R17177 |
T20084 |
T20086 |
det |
a,decrease |
R17178 |
T20085 |
T20086 |
amod |
time-dependent,decrease |
R17179 |
T20086 |
T20083 |
dobj |
decrease,demonstrated |
R17180 |
T20087 |
T20086 |
prep |
in,decrease |
R17181 |
T20088 |
T20089 |
amod |
nuclear,expression |
R17182 |
T20089 |
T20087 |
pobj |
expression,in |
R17183 |
T20090 |
T20089 |
prep |
of,expression |
R17184 |
T20091 |
T20090 |
pobj |
GATA-3,of |
R17185 |
T20092 |
T20083 |
punct |
",",demonstrated |
R17186 |
T20093 |
T20083 |
cc |
and,demonstrated |
R17187 |
T20094 |
T20097 |
amod |
increased,expression |
R17188 |
T20095 |
T20097 |
amod |
cytoplasmic,expression |
R17189 |
T20096 |
T20097 |
amod |
GATA-3,expression |
R17190 |
T20097 |
T20083 |
conj |
expression,demonstrated |
R17191 |
T20098 |
T20097 |
prep |
after,expression |
R17192 |
T20099 |
T20098 |
pobj |
inhalation,after |
R17193 |
T20100 |
T20099 |
prep |
of,inhalation |
R17194 |
T20101 |
T20100 |
pobj |
FP,of |
R17195 |
T20102 |
T20083 |
punct |
.,demonstrated |
R17196 |
T20103 |
T20110 |
punct |
(,demonstrated |
R17197 |
T20104 |
T20107 |
compound |
D,analyses |
R17198 |
T20105 |
T20106 |
punct |
),Immunoblotting |
R17199 |
T20106 |
T20107 |
compound |
Immunoblotting,analyses |
R17200 |
T20107 |
T20110 |
nsubj |
analyses,demonstrated |
R17201 |
T20108 |
T20107 |
prep |
of,analyses |
R17202 |
T20109 |
T20108 |
pobj |
PBMCs,of |
R17203 |
T20110 |
T20110 |
ROOT |
demonstrated,demonstrated |
R17204 |
T20111 |
T20113 |
det |
a,decrease |
R17205 |
T20112 |
T20113 |
amod |
dose-dependent,decrease |
R17206 |
T20113 |
T20110 |
dobj |
decrease,demonstrated |
R17207 |
T20114 |
T20113 |
prep |
in,decrease |
R17208 |
T20115 |
T20116 |
amod |
nuclear,expression |
R17209 |
T20116 |
T20114 |
pobj |
expression,in |
R17210 |
T20117 |
T20116 |
prep |
of,expression |
R17211 |
T20118 |
T20117 |
pobj |
GATA-3,of |
R17212 |
T20119 |
T20110 |
punct |
",",demonstrated |
R17213 |
T20120 |
T20110 |
cc |
and,demonstrated |
R17214 |
T20121 |
T20110 |
conj |
increased,demonstrated |
R17215 |
T20122 |
T20124 |
amod |
cytoplasmic,expression |
R17216 |
T20123 |
T20124 |
amod |
GATA-3,expression |
R17217 |
T20124 |
T20121 |
dobj |
expression,increased |
R17218 |
T20125 |
T20126 |
nummod |
2,h |
R17219 |
T20126 |
T20124 |
appos |
h,expression |
R17220 |
T20127 |
T20126 |
prep |
after,h |
R17221 |
T20128 |
T20127 |
pobj |
inhalation,after |
R17222 |
T20129 |
T20128 |
prep |
of,inhalation |
R17223 |
T20130 |
T20129 |
pobj |
FP,of |
R17224 |
T20131 |
T20110 |
punct |
.,demonstrated |
R17225 |
T20132 |
T20133 |
compound |
Histone,H1 |
R17226 |
T20133 |
T20137 |
nsubj |
H1,confirmed |
R17227 |
T20134 |
T20133 |
cc |
and,H1 |
R17228 |
T20135 |
T20133 |
conj |
MEK-1,H1 |
R17229 |
T20136 |
T20137 |
nsubj |
immunoblotting,confirmed |
R17230 |
T20137 |
T20137 |
ROOT |
confirmed,confirmed |
R17231 |
T20138 |
T20141 |
amod |
equivalent,loading |
R17232 |
T20139 |
T20140 |
amod |
total,protein |
R17233 |
T20140 |
T20141 |
compound |
protein,loading |
R17234 |
T20141 |
T20137 |
dobj |
loading,confirmed |
R17235 |
T20142 |
T20141 |
prep |
for,loading |
R17236 |
T20143 |
T20147 |
det |
the,fractions |
R17237 |
T20144 |
T20147 |
amod |
nuclear,fractions |
R17238 |
T20145 |
T20144 |
cc |
and,nuclear |
R17239 |
T20146 |
T20144 |
conj |
cytoplasmic,nuclear |
R17240 |
T20147 |
T20142 |
pobj |
fractions,for |
R17241 |
T20148 |
T20137 |
advmod |
respectively,confirmed |
R17242 |
T20149 |
T20137 |
punct |
.,confirmed |
R17243 |
T20150 |
T20164 |
nsubjpass |
Quantification,shown |
R17244 |
T20151 |
T20150 |
prep |
of,Quantification |
R17245 |
T20152 |
T20154 |
det |
the,data |
R17246 |
T20153 |
T20154 |
compound |
densitometry,data |
R17247 |
T20154 |
T20151 |
pobj |
data,of |
R17248 |
T20155 |
T20154 |
prep |
in,data |
R17249 |
T20156 |
T20157 |
punct |
(,C |
R17250 |
T20157 |
T20155 |
pobj |
C,in |
R17251 |
T20158 |
T20150 |
punct |
),Quantification |
R17252 |
T20159 |
T20150 |
cc |
and,Quantification |
R17253 |
T20160 |
T20161 |
punct |
(,D |
R17254 |
T20161 |
T20150 |
conj |
D,Quantification |
R17255 |
T20162 |
T20161 |
punct |
),D |
R17256 |
T20163 |
T20164 |
auxpass |
is,shown |
R17257 |
T20164 |
T20164 |
ROOT |
shown,shown |
R17258 |
T20165 |
T20164 |
prep |
as,shown |
R17259 |
T20166 |
T20168 |
det |
a,plot |
R17260 |
T20167 |
T20168 |
compound |
box-and-whiskers,plot |
R17261 |
T20168 |
T20165 |
pobj |
plot,as |
R17262 |
T20169 |
T20168 |
prep |
of,plot |
R17263 |
T20170 |
T20169 |
pobj |
results,of |
R17264 |
T20171 |
T20170 |
prep |
from,results |
R17265 |
T20172 |
T20175 |
amod |
n,participants |
R17266 |
T20173 |
T20174 |
punct |
=,6 |
R17267 |
T20174 |
T20175 |
nummod |
6,participants |
R17268 |
T20175 |
T20171 |
pobj |
participants,from |
R17269 |
T20176 |
T20179 |
prep |
for,were |
R17270 |
T20177 |
T20176 |
pobj |
which,for |
R17271 |
T20178 |
T20179 |
nsubj |
data,were |
R17272 |
T20179 |
T20175 |
relcl |
were,participants |
R17273 |
T20180 |
T20179 |
acomp |
available,were |
R17274 |
T20181 |
T20164 |
punct |
.,shown |
R17275 |
T20182 |
T20186 |
advmod |
*,compared |
R17276 |
T20183 |
T20184 |
compound |
p,< |
R17277 |
T20184 |
T20185 |
compound |
<,0.05 |
R17278 |
T20185 |
T20186 |
advmod |
0.05,compared |
R17279 |
T20186 |
T20186 |
ROOT |
compared,compared |
R17280 |
T20187 |
T20188 |
aux |
to,control |
R17281 |
T20188 |
T20186 |
xcomp |
control,compared |
R17282 |
T20189 |
T20164 |
punct |
.,shown |
R17283 |
T20190 |
T20198 |
punct |
(,demonstrated |
R17284 |
T20191 |
T20195 |
nmod |
E,analyses |
R17285 |
T20192 |
T20191 |
punct |
),E |
R17286 |
T20193 |
T20195 |
amod |
Western,analyses |
R17287 |
T20194 |
T20195 |
compound |
blot,analyses |
R17288 |
T20195 |
T20198 |
nsubj |
analyses,demonstrated |
R17289 |
T20196 |
T20195 |
prep |
of,analyses |
R17290 |
T20197 |
T20196 |
pobj |
PBMCs,of |
R17291 |
T20198 |
T20198 |
ROOT |
demonstrated,demonstrated |
R17292 |
T20199 |
T20201 |
det |
a,decrease |
R17293 |
T20200 |
T20201 |
amod |
time-dependent,decrease |
R17294 |
T20201 |
T20198 |
dobj |
decrease,demonstrated |
R17295 |
T20202 |
T20201 |
prep |
in,decrease |
R17296 |
T20203 |
T20204 |
amod |
dual,phosphorylation |
R17297 |
T20204 |
T20202 |
pobj |
phosphorylation,in |
R17298 |
T20205 |
T20206 |
punct |
(,threonine-180 |
R17299 |
T20206 |
T20204 |
appos |
threonine-180,phosphorylation |
R17300 |
T20207 |
T20206 |
cc |
and,threonine-180 |
R17301 |
T20208 |
T20206 |
conj |
tyrosine-182,threonine-180 |
R17302 |
T20209 |
T20206 |
punct |
),threonine-180 |
R17303 |
T20210 |
T20206 |
prep |
of,threonine-180 |
R17304 |
T20211 |
T20212 |
nummod |
p38,MAPK |
R17305 |
T20212 |
T20210 |
pobj |
MAPK,of |
R17306 |
T20213 |
T20198 |
prep |
after,demonstrated |
R17307 |
T20214 |
T20213 |
pobj |
inhalation,after |
R17308 |
T20215 |
T20214 |
prep |
of,inhalation |
R17309 |
T20216 |
T20215 |
pobj |
FP,of |
R17310 |
T20217 |
T20219 |
punct |
(,µg |
R17311 |
T20218 |
T20219 |
nummod |
500,µg |
R17312 |
T20219 |
T20216 |
appos |
µg,FP |
R17313 |
T20220 |
T20219 |
punct |
),µg |
R17314 |
T20221 |
T20198 |
punct |
.,demonstrated |
R17315 |
T20222 |
T20223 |
det |
The,results |
R17316 |
T20223 |
T20229 |
nsubj |
results,are |
R17317 |
T20224 |
T20223 |
acl |
shown,results |
R17318 |
T20225 |
T20224 |
prep |
in,shown |
R17319 |
T20226 |
T20227 |
punct |
(,E |
R17320 |
T20227 |
T20225 |
pobj |
E,in |
R17321 |
T20228 |
T20223 |
punct |
),results |
R17322 |
T20229 |
T20229 |
ROOT |
are,are |
R17323 |
T20230 |
T20229 |
attr |
representative,are |
R17324 |
T20231 |
T20230 |
prep |
of,representative |
R17325 |
T20232 |
T20231 |
pobj |
samples,of |
R17326 |
T20233 |
T20232 |
prep |
from,samples |
R17327 |
T20234 |
T20235 |
nummod |
two,participants |
R17328 |
T20235 |
T20233 |
pobj |
participants,from |
R17329 |
T20236 |
T20229 |
punct |
.,are |
R1967 |
T2279 |
T2293 |
nsubjpass |
Inflammation,mediated |
R1968 |
T2280 |
T2279 |
prep |
in,Inflammation |
R1969 |
T2281 |
T2282 |
amod |
allergic,diseases |
R1970 |
T2282 |
T2280 |
pobj |
diseases,in |
R1971 |
T2283 |
T2284 |
amod |
such,as |
R1972 |
T2284 |
T2282 |
prep |
as,diseases |
R1973 |
T2285 |
T2284 |
pobj |
asthma,as |
R1974 |
T2286 |
T2285 |
punct |
",",asthma |
R1975 |
T2287 |
T2285 |
conj |
rhinitis,asthma |
R1976 |
T2288 |
T2287 |
punct |
",",rhinitis |
R1977 |
T2289 |
T2287 |
cc |
and,rhinitis |
R1978 |
T2290 |
T2291 |
amod |
atopic,dermatitis |
R1979 |
T2291 |
T2287 |
conj |
dermatitis,rhinitis |
R1980 |
T2292 |
T2293 |
auxpass |
is,mediated |
R1981 |
T2293 |
T2293 |
ROOT |
mediated,mediated |
R1982 |
T2294 |
T2293 |
prep |
via,mediated |
R1983 |
T2295 |
T2294 |
pobj |
expression,via |
R1984 |
T2296 |
T2295 |
prep |
of,expression |
R1985 |
T2297 |
T2298 |
det |
the,cytokines |
R1986 |
T2298 |
T2296 |
pobj |
cytokines,of |
R1987 |
T2299 |
T2293 |
conj |
interleukin,mediated |
R1988 |
T2300 |
T2301 |
punct |
(,IL |
R1989 |
T2301 |
T2299 |
appos |
IL,interleukin |
R1990 |
T2302 |
T2301 |
punct |
),IL |
R1991 |
T2303 |
T2301 |
nummod |
-4,IL |
R1992 |
T2327 |
T2325 |
pobj |
lymphocytes,from |
R1993 |
T2304 |
T2301 |
punct |
",",IL |
R1994 |
T2328 |
T2320 |
punct |
",",regulate |
R1995 |
T2305 |
T2301 |
appos |
IL-5,IL |
R1996 |
T2306 |
T2305 |
punct |
",",IL-5 |
R1997 |
T2329 |
T2331 |
mark |
whereas,plays |
R1998 |
T2307 |
T2305 |
cc |
and,IL-5 |
R1999 |
T2330 |
T2331 |
nsubj |
IL-5,plays |
R2000 |
T2331 |
T2320 |
advcl |
plays,regulate |
R2001 |
T2308 |
T2305 |
conj |
IL-13,IL-5 |
R2002 |
T2332 |
T2334 |
det |
a,role |
R2003 |
T2333 |
T2334 |
amod |
key,role |
R2004 |
T2334 |
T2331 |
dobj |
role,plays |
R2005 |
T2335 |
T2334 |
prep |
in,role |
R2006 |
T2309 |
T2308 |
prep |
from,IL-13 |
R2007 |
T2336 |
T2337 |
amod |
eosinophilic,inflammation |
R2008 |
T2337 |
T2335 |
pobj |
inflammation,in |
R2009 |
T2310 |
T2311 |
compound |
T,helper-2 |
R2010 |
T2338 |
T2340 |
quantmod |
[,] |
R2011 |
T2339 |
T2340 |
nummod |
1,] |
R2012 |
T2340 |
T2331 |
npadvmod |
],plays |
R2013 |
T2311 |
T2309 |
pobj |
helper-2,from |
R2014 |
T2341 |
T2320 |
punct |
.,regulate |
R2015 |
T2342 |
T2343 |
nummod |
Th2,cytokines |
R2016 |
T2343 |
T2345 |
nsubjpass |
cytokines,regulated |
R2017 |
T2312 |
T2311 |
punct |
(,helper-2 |
R2018 |
T2344 |
T2345 |
auxpass |
are,regulated |
R2019 |
T2313 |
T2311 |
appos |
Th2,helper-2 |
R2020 |
T2314 |
T2311 |
punct |
),helper-2 |
R2021 |
T2315 |
T2309 |
pobj |
cells,from |
R2022 |
T2345 |
T2345 |
ROOT |
regulated,regulated |
R2023 |
T2346 |
T2345 |
agent |
by,regulated |
R2024 |
T2347 |
T2351 |
det |
the,factor |
R2025 |
T2348 |
T2350 |
compound |
zinc,transcription |
R2026 |
T2349 |
T2350 |
compound |
finger,transcription |
R2027 |
T2316 |
T2293 |
punct |
.,mediated |
R2028 |
T2350 |
T2351 |
compound |
transcription,factor |
R2029 |
T2351 |
T2346 |
pobj |
factor,by |
R2030 |
T2317 |
T2320 |
nsubj |
IL-4,regulate |
R2031 |
T2352 |
T2351 |
appos |
GATA-3,factor |
R2032 |
T2353 |
T2351 |
punct |
",",factor |
R2033 |
T2354 |
T2357 |
nsubjpass |
which,expressed |
R2034 |
T2318 |
T2317 |
cc |
and,IL-4 |
R2035 |
T2355 |
T2357 |
auxpass |
is,expressed |
R2036 |
T2356 |
T2357 |
advmod |
predominantly,expressed |
R2037 |
T2357 |
T2351 |
relcl |
expressed,factor |
R2038 |
T2319 |
T2317 |
conj |
IL-13,IL-4 |
R2039 |
T2358 |
T2357 |
prep |
in,expressed |
R2040 |
T2320 |
T2320 |
ROOT |
regulate,regulate |
R2041 |
T2321 |
T2322 |
det |
the,expression |
R2042 |
T2359 |
T2360 |
amod |
Th2,cells |
R2043 |
T2322 |
T2320 |
dobj |
expression,regulate |
R2044 |
T2360 |
T2358 |
pobj |
cells,in |
R2045 |
T2361 |
T2363 |
nmod |
[,] |
R2046 |
T2362 |
T2363 |
nummod |
2,] |
R2047 |
T2363 |
T2367 |
nmod |
],] |
R2048 |
T2323 |
T2322 |
prep |
of,expression |
R2049 |
T2364 |
T2363 |
punct |
",",] |
R2050 |
T2324 |
T2323 |
pobj |
IgE,of |
R2051 |
T2325 |
T2320 |
prep |
from,regulate |
R2052 |
T2365 |
T2363 |
conj |
[,] |
R2053 |
T2326 |
T2327 |
compound |
B,lymphocytes |
R2054 |
T2366 |
T2367 |
nummod |
3,] |
R2055 |
T2367 |
T2345 |
npadvmod |
],regulated |
R2056 |
T2368 |
T2345 |
punct |
.,regulated |
R2057 |
T2456 |
T2454 |
pobj |
cytokines,of |
R2058 |
T2369 |
T2370 |
nsubj |
GATA-3,determines |
R2059 |
T2370 |
T2370 |
ROOT |
determines,determines |
R2060 |
T2371 |
T2373 |
compound |
Th2,differentiation |
R2061 |
T2372 |
T2373 |
compound |
cell,differentiation |
R2062 |
T2457 |
T2452 |
prep |
in,reduces |
R2063 |
T2373 |
T2370 |
dobj |
differentiation,determines |
R2064 |
T2374 |
T2370 |
cc |
and,determines |
R2065 |
T2375 |
T2376 |
advmod |
selectively,activates |
R2066 |
T2458 |
T2457 |
pobj |
vitro,in |
R2067 |
T2376 |
T2370 |
conj |
activates,determines |
R2068 |
T2377 |
T2378 |
det |
the,promoters |
R2069 |
T2378 |
T2376 |
dobj |
promoters,activates |
R2070 |
T2459 |
T2457 |
cc |
and,in |
R2071 |
T2379 |
T2378 |
prep |
of,promoters |
R2072 |
T2380 |
T2379 |
pobj |
IL-4,of |
R2073 |
T2381 |
T2380 |
punct |
",",IL-4 |
R2074 |
T2382 |
T2380 |
conj |
IL-5,IL-4 |
R2075 |
T2383 |
T2382 |
punct |
",",IL-5 |
R2076 |
T2384 |
T2382 |
cc |
and,IL-5 |
R2077 |
T2385 |
T2382 |
conj |
IL-13,IL-5 |
R2078 |
T2460 |
T2457 |
conj |
in,in |
R2079 |
T2386 |
T2376 |
prep |
through,activates |
R2080 |
T2387 |
T2388 |
compound |
chromatin,remodelling |
R2081 |
T2388 |
T2389 |
compound |
remodelling,[ |
R2082 |
T2389 |
T2391 |
nmod |
[,] |
R2083 |
T2461 |
T2460 |
pobj |
vivo,in |
R2084 |
T2390 |
T2391 |
nummod |
4,] |
R2085 |
T2391 |
T2386 |
pobj |
],through |
R2086 |
T2392 |
T2394 |
nmod |
[,] |
R2087 |
T2462 |
T2464 |
nmod |
[,] |
R2088 |
T2393 |
T2392 |
nummod |
7,[ |
R2089 |
T2394 |
T2391 |
appos |
],] |
R2090 |
T2463 |
T2464 |
nummod |
10,] |
R2091 |
T2395 |
T2370 |
punct |
.,determines |
R2092 |
T2396 |
T2398 |
det |
The,role |
R2093 |
T2397 |
T2398 |
amod |
key,role |
R2094 |
T2464 |
T2452 |
dobj |
],reduces |
R2095 |
T2398 |
T2407 |
nsubjpass |
role,demonstrated |
R2096 |
T2399 |
T2398 |
prep |
of,role |
R2097 |
T2400 |
T2399 |
pobj |
GATA-3,of |
R2098 |
T2465 |
T2464 |
punct |
",",] |
R2099 |
T2401 |
T2400 |
prep |
in,GATA-3 |
R2100 |
T2402 |
T2404 |
amod |
allergic,inflammation |
R2101 |
T2403 |
T2404 |
compound |
airway,inflammation |
R2102 |
T2466 |
T2464 |
cc |
and,] |
R2103 |
T2404 |
T2401 |
pobj |
inflammation,in |
R2104 |
T2405 |
T2407 |
aux |
has,demonstrated |
R2105 |
T2406 |
T2407 |
auxpass |
been,demonstrated |
R2106 |
T2407 |
T2407 |
ROOT |
demonstrated,demonstrated |
R2107 |
T2467 |
T2468 |
amod |
similar,results |
R2108 |
T2408 |
T2407 |
prep |
in,demonstrated |
R2109 |
T2409 |
T2408 |
pobj |
mice,in |
R2110 |
T2468 |
T2464 |
conj |
results,] |
R2111 |
T2410 |
T2407 |
agent |
by,demonstrated |
R2112 |
T2469 |
T2471 |
aux |
have,reported |
R2113 |
T2411 |
T2413 |
det |
the,release |
R2114 |
T2470 |
T2471 |
auxpass |
been,reported |
R2115 |
T2412 |
T2413 |
amod |
reduced,release |
R2116 |
T2471 |
T2452 |
conj |
reported,reduces |
R2117 |
T2413 |
T2410 |
pobj |
release,by |
R2118 |
T2414 |
T2413 |
prep |
of,release |
R2119 |
T2415 |
T2416 |
amod |
Th2,cytokines |
R2120 |
T2472 |
T2471 |
prep |
in,reported |
R2121 |
T2416 |
T2414 |
pobj |
cytokines,of |
R2122 |
T2417 |
T2416 |
prep |
in,cytokines |
R2123 |
T2418 |
T2417 |
pobj |
animals,in |
R2124 |
T2473 |
T2474 |
amod |
isolated,murine |
R2125 |
T2419 |
T2418 |
acl |
treated,animals |
R2126 |
T2420 |
T2419 |
prep |
with,treated |
R2127 |
T2421 |
T2422 |
amod |
dominant-negative,mutants |
R2128 |
T2474 |
T2472 |
pobj |
murine,in |
R2129 |
T2422 |
T2420 |
pobj |
mutants,with |
R2130 |
T2423 |
T2422 |
prep |
of,mutants |
R2131 |
T2475 |
T2476 |
compound |
CD4,+ |
R2132 |
T2476 |
T2477 |
nsubj |
+,lymphocytes |
R2133 |
T2424 |
T2423 |
pobj |
GATA-3,of |
R2134 |
T2425 |
T2420 |
cc |
and,with |
R2135 |
T2426 |
T2419 |
agent |
by,treated |
R2136 |
T2477 |
T2471 |
parataxis |
lymphocytes,reported |
R2137 |
T2427 |
T2428 |
amod |
local,application |
R2138 |
T2428 |
T2426 |
pobj |
application,by |
R2139 |
T2429 |
T2428 |
prep |
of,application |
R2140 |
T2478 |
T2480 |
nmod |
[,] |
R2141 |
T2430 |
T2431 |
amod |
antisense,oligonucleotides |
R2142 |
T2431 |
T2429 |
pobj |
oligonucleotides,of |
R2143 |
T2479 |
T2480 |
nummod |
11,] |
R2144 |
T2432 |
T2419 |
prep |
to,treated |
R2145 |
T2433 |
T2436 |
nmod |
GATA-3,] |
R2146 |
T2434 |
T2436 |
nmod |
[,] |
R2147 |
T2480 |
T2477 |
dobj |
],lymphocytes |
R2148 |
T2435 |
T2436 |
nummod |
8,] |
R2149 |
T2436 |
T2432 |
pobj |
],to |
R2150 |
T2437 |
T2436 |
punct |
",",] |
R2151 |
T2438 |
T2440 |
nmod |
[,] |
R2152 |
T2481 |
T2477 |
punct |
.,lymphocytes |
R2153 |
T2439 |
T2440 |
nummod |
9,] |
R2154 |
T2440 |
T2436 |
appos |
],] |
R2155 |
T2482 |
T2488 |
advmod |
Finally,using |
R2156 |
T2441 |
T2407 |
punct |
.,demonstrated |
R2157 |
T2442 |
T2452 |
advmod |
Furthermore,reduces |
R2158 |
T2443 |
T2445 |
punct |
",",knock-out |
R2159 |
T2483 |
T2488 |
punct |
",",using |
R2160 |
T2444 |
T2445 |
amod |
conditional,knock-out |
R2161 |
T2445 |
T2452 |
nsubj |
knock-out,reduces |
R2162 |
T2446 |
T2445 |
prep |
of,knock-out |
R2163 |
T2484 |
T2488 |
nsubj |
knockdown,using |
R2164 |
T2447 |
T2449 |
det |
the,gene |
R2165 |
T2448 |
T2449 |
compound |
Gata3,gene |
R2166 |
T2449 |
T2446 |
pobj |
gene,of |
R2167 |
T2450 |
T2445 |
prep |
in,knock-out |
R2168 |
T2485 |
T2484 |
prep |
of,knockdown |
R2169 |
T2451 |
T2450 |
pobj |
mice,in |
R2170 |
T2452 |
T2452 |
ROOT |
reduces,reduces |
R2171 |
T2486 |
T2487 |
amod |
GATA-3,expression |
R2172 |
T2453 |
T2452 |
dobj |
expression,reduces |
R2173 |
T2454 |
T2453 |
prep |
of,expression |
R2174 |
T2455 |
T2456 |
compound |
Th2,cytokines |
R2175 |
T2487 |
T2485 |
pobj |
expression,of |
R2176 |
T2488 |
T2488 |
ROOT |
using,using |
R2177 |
T2489 |
T2488 |
dobj |
siRNA,using |
R2178 |
T2490 |
T2488 |
prep |
in,using |
R2179 |
T2491 |
T2493 |
amod |
human,cells |
R2180 |
T2553 |
T2555 |
auxpass |
was,confirmed |
R2181 |
T2554 |
T2555 |
advmod |
recently,confirmed |
R2182 |
T2492 |
T2493 |
compound |
T,cells |
R2183 |
T2555 |
T2544 |
conj |
confirmed,demonstrated |
R2184 |
T2556 |
T2555 |
prep |
in,confirmed |
R2185 |
T2557 |
T2559 |
amod |
human,cells |
R2186 |
T2493 |
T2494 |
compound |
cells,results |
R2187 |
T2558 |
T2559 |
compound |
T,cells |
R2188 |
T2559 |
T2556 |
pobj |
cells,in |
R2189 |
T2560 |
T2555 |
prep |
following,confirmed |
R2190 |
T2494 |
T2490 |
pobj |
results,in |
R2191 |
T2561 |
T2563 |
compound |
T,receptor |
R2192 |
T2562 |
T2563 |
compound |
cell,receptor |
R2193 |
T2563 |
T2560 |
pobj |
receptor,following |
R2194 |
T2495 |
T2494 |
prep |
in,results |
R2195 |
T2564 |
T2563 |
cc |
and,receptor |
R2196 |
T2565 |
T2566 |
compound |
co-receptor,stimulation |
R2197 |
T2496 |
T2495 |
pobj |
loss,in |
R2198 |
T2566 |
T2563 |
conj |
stimulation,receptor |
R2199 |
T2567 |
T2569 |
nmod |
[,] |
R2200 |
T2568 |
T2569 |
nummod |
12,] |
R2201 |
T2497 |
T2496 |
prep |
of,loss |
R2202 |
T2569 |
T2566 |
nmod |
],stimulation |
R2203 |
T2570 |
T2544 |
punct |
.,demonstrated |
R2204 |
T2571 |
T2572 |
nsubj |
GATA-3,contains |
R2205 |
T2498 |
T2503 |
amod |
anti-CD3,expression |
R2206 |
T2499 |
T2503 |
nmod |
/,expression |
R2207 |
T2572 |
T2572 |
ROOT |
contains,contains |
R2208 |
T2500 |
T2503 |
nmod |
CD28-mediated,expression |
R2209 |
T2573 |
T2577 |
det |
a,signal |
R2210 |
T2574 |
T2577 |
amod |
classical,signal |
R2211 |
T2501 |
T2503 |
amod |
Th2,expression |
R2212 |
T2575 |
T2576 |
amod |
nuclear,import |
R2213 |
T2576 |
T2577 |
compound |
import,signal |
R2214 |
T2577 |
T2572 |
dobj |
signal,contains |
R2215 |
T2502 |
T2503 |
compound |
cytokine,expression |
R2216 |
T2578 |
T2580 |
nmod |
[,] |
R2217 |
T2579 |
T2580 |
nummod |
14,] |
R2218 |
T2580 |
T2577 |
appos |
],signal |
R2219 |
T2503 |
T2497 |
pobj |
expression,of |
R2220 |
T2581 |
T2572 |
cc |
and,contains |
R2221 |
T2504 |
T2506 |
nmod |
[,] |
R2222 |
T2582 |
T2583 |
auxpass |
is,transported |
R2223 |
T2505 |
T2506 |
nummod |
12,] |
R2224 |
T2583 |
T2572 |
conj |
transported,contains |
R2225 |
T2584 |
T2583 |
prep |
into,transported |
R2226 |
T2585 |
T2586 |
det |
the,nucleus |
R2227 |
T2586 |
T2584 |
pobj |
nucleus,into |
R2228 |
T2587 |
T2583 |
agent |
by,transported |
R2229 |
T2506 |
T2503 |
appos |
],expression |
R2230 |
T2588 |
T2591 |
det |
the,protein |
R2231 |
T2589 |
T2591 |
amod |
nuclear,protein |
R2232 |
T2590 |
T2591 |
compound |
import,protein |
R2233 |
T2507 |
T2488 |
punct |
.,using |
R2234 |
T2591 |
T2587 |
pobj |
protein,by |
R2235 |
T2592 |
T2583 |
conj |
importin-α,transported |
R2236 |
T2593 |
T2595 |
punct |
(,known |
R2237 |
T2508 |
T2519 |
prep |
In,translocate |
R2238 |
T2594 |
T2595 |
advmod |
also,known |
R2239 |
T2595 |
T2592 |
acl |
known,importin-α |
R2240 |
T2596 |
T2595 |
prep |
as,known |
R2241 |
T2509 |
T2508 |
pobj |
order,In |
R2242 |
T2597 |
T2596 |
pobj |
karyopherin-α,as |
R2243 |
T2598 |
T2592 |
punct |
),importin-α |
R2244 |
T2599 |
T2601 |
nmod |
[,] |
R2245 |
T2510 |
T2513 |
mark |
for,regulate |
R2246 |
T2600 |
T2601 |
nummod |
12,] |
R2247 |
T2601 |
T2572 |
dep |
],contains |
R2248 |
T2602 |
T2572 |
punct |
.,contains |
R2249 |
T2511 |
T2513 |
nsubj |
GATA-3,regulate |
R2250 |
T2603 |
T2622 |
nsubj |
Deletion,prevents |
R2251 |
T2604 |
T2603 |
prep |
of,Deletion |
R2252 |
T2605 |
T2606 |
det |
a,region |
R2253 |
T2512 |
T2513 |
aux |
to,regulate |
R2254 |
T2606 |
T2604 |
pobj |
region,of |
R2255 |
T2607 |
T2606 |
acl |
encompassing,region |
R2256 |
T2608 |
T2612 |
det |
the,sequence |
R2257 |
T2513 |
T2509 |
advcl |
regulate,order |
R2258 |
T2609 |
T2612 |
amod |
GATA-3,sequence |
R2259 |
T2610 |
T2611 |
amod |
nuclear,localisation |
R2260 |
T2514 |
T2515 |
compound |
gene,expression |
R2261 |
T2611 |
T2612 |
compound |
localisation,sequence |
R2262 |
T2515 |
T2513 |
dobj |
expression,regulate |
R2263 |
T2612 |
T2607 |
dobj |
sequence,encompassing |
R2264 |
T2613 |
T2612 |
punct |
(,sequence |
R2265 |
T2614 |
T2612 |
appos |
NLS,sequence |
R2266 |
T2516 |
T2519 |
punct |
",",translocate |
R2267 |
T2615 |
T2612 |
punct |
),sequence |
R2268 |
T2616 |
T2606 |
conj |
region,region |
R2269 |
T2617 |
T2603 |
prep |
in,Deletion |
R2270 |
T2517 |
T2519 |
nsubj |
it,translocate |
R2271 |
T2618 |
T2617 |
pobj |
murine,in |
R2272 |
T2619 |
T2618 |
cc |
and,murine |
R2273 |
T2620 |
T2621 |
amod |
human,cells |
R2274 |
T2518 |
T2519 |
aux |
must,translocate |
R2275 |
T2621 |
T2618 |
conj |
cells,murine |
R2276 |
T2622 |
T2622 |
ROOT |
prevents,prevents |
R2277 |
T2623 |
T2625 |
poss |
its,localisation |
R2278 |
T2624 |
T2625 |
amod |
nuclear,localisation |
R2279 |
T2625 |
T2622 |
dobj |
localisation,prevents |
R2280 |
T2519 |
T2519 |
ROOT |
translocate,translocate |
R2281 |
T2626 |
T2628 |
nmod |
[,] |
R2282 |
T2520 |
T2519 |
prep |
from,translocate |
R2283 |
T2627 |
T2628 |
nummod |
12,] |
R2284 |
T2628 |
T2622 |
dobj |
],prevents |
R2285 |
T2629 |
T2628 |
punct |
",",] |
R2286 |
T2521 |
T2522 |
det |
the,cytoplasm |
R2287 |
T2630 |
T2628 |
conj |
[,] |
R2288 |
T2631 |
T2632 |
nummod |
14,] |
R2289 |
T2632 |
T2628 |
conj |
],] |
R2290 |
T2522 |
T2520 |
pobj |
cytoplasm,from |
R2291 |
T2633 |
T2622 |
punct |
.,prevents |
R2292 |
T2634 |
T2635 |
det |
The,affinity |
R2293 |
T2635 |
T2642 |
nsubjpass |
affinity,regulated |
R2294 |
T2523 |
T2519 |
prep |
into,translocate |
R2295 |
T2636 |
T2635 |
prep |
of,affinity |
R2296 |
T2637 |
T2638 |
det |
the,importin-α |
R2297 |
T2638 |
T2636 |
pobj |
importin-α,of |
R2298 |
T2524 |
T2525 |
det |
the,nucleus |
R2299 |
T2639 |
T2640 |
compound |
NLS,interaction |
R2300 |
T2640 |
T2642 |
nsubjpass |
interaction,regulated |
R2301 |
T2641 |
T2642 |
auxpass |
is,regulated |
R2302 |
T2525 |
T2523 |
pobj |
nucleus,into |
R2303 |
T2642 |
T2642 |
ROOT |
regulated,regulated |
R2304 |
T2643 |
T2642 |
agent |
by,regulated |
R2305 |
T2644 |
T2645 |
compound |
phosphorylation,[ |
R2306 |
T2526 |
T2527 |
aux |
to,access |
R2307 |
T2645 |
T2647 |
nmod |
[,] |
R2308 |
T2646 |
T2647 |
nummod |
15,] |
R2309 |
T2647 |
T2643 |
pobj |
],by |
R2310 |
T2527 |
T2519 |
advcl |
access,translocate |
R2311 |
T2648 |
T2642 |
punct |
",",regulated |
R2312 |
T2649 |
T2642 |
cc |
and,regulated |
R2313 |
T2528 |
T2530 |
poss |
its,genes |
R2314 |
T2529 |
T2530 |
compound |
target,genes |
R2315 |
T2650 |
T2652 |
nsubj |
we,shown |
R2316 |
T2530 |
T2527 |
dobj |
genes,access |
R2317 |
T2651 |
T2652 |
aux |
have,shown |
R2318 |
T2652 |
T2642 |
conj |
shown,regulated |
R2319 |
T2653 |
T2661 |
mark |
that,plays |
R2320 |
T2531 |
T2519 |
punct |
.,translocate |
R2321 |
T2654 |
T2657 |
nummod |
p38,kinase |
R2322 |
T2655 |
T2657 |
amod |
mitogen-activated,kinase |
R2323 |
T2656 |
T2657 |
compound |
protein,kinase |
R2324 |
T2532 |
T2534 |
amod |
Enhanced,expression |
R2325 |
T2657 |
T2661 |
nsubj |
kinase,plays |
R2326 |
T2658 |
T2659 |
punct |
(,MAPK |
R2327 |
T2533 |
T2534 |
amod |
nuclear,expression |
R2328 |
T2659 |
T2657 |
appos |
MAPK,kinase |
R2329 |
T2660 |
T2657 |
punct |
),kinase |
R2330 |
T2534 |
T2544 |
nsubjpass |
expression,demonstrated |
R2331 |
T2661 |
T2652 |
ccomp |
plays,shown |
R2332 |
T2662 |
T2664 |
det |
a,role |
R2333 |
T2663 |
T2664 |
amod |
critical,role |
R2334 |
T2535 |
T2534 |
prep |
of,expression |
R2335 |
T2664 |
T2661 |
dobj |
role,plays |
R2336 |
T2665 |
T2664 |
prep |
in,role |
R2337 |
T2536 |
T2535 |
pobj |
GATA-3,of |
R2338 |
T2537 |
T2534 |
acl |
following,expression |
R2339 |
T2666 |
T2665 |
pcomp |
phosphorylating,in |
R2340 |
T2667 |
T2666 |
dobj |
GATA-3,phosphorylating |
R2341 |
T2538 |
T2541 |
compound |
T,activation |
R2342 |
T2668 |
T2669 |
aux |
to,enhance |
R2343 |
T2669 |
T2661 |
advcl |
enhance,plays |
R2344 |
T2670 |
T2671 |
poss |
its,interaction |
R2345 |
T2539 |
T2540 |
compound |
cell,receptor |
R2346 |
T2671 |
T2669 |
dobj |
interaction,enhance |
R2347 |
T2672 |
T2671 |
prep |
with,interaction |
R2348 |
T2673 |
T2676 |
amod |
importin-α,transport |
R2349 |
T2674 |
T2673 |
cc |
and,importin-α |
R2350 |
T2540 |
T2541 |
compound |
receptor,activation |
R2351 |
T2675 |
T2673 |
conj |
subsequent,importin-α |
R2352 |
T2676 |
T2672 |
pobj |
transport,with |
R2353 |
T2541 |
T2537 |
pobj |
activation,following |
R2354 |
T2677 |
T2669 |
prep |
into,enhance |
R2355 |
T2678 |
T2679 |
det |
the,nucleus |
R2356 |
T2679 |
T2677 |
pobj |
nucleus,into |
R2357 |
T2542 |
T2544 |
auxpass |
was,demonstrated |
R2358 |
T2680 |
T2682 |
nmod |
[,] |
R2359 |
T2681 |
T2682 |
nummod |
12,] |
R2360 |
T2682 |
T2679 |
appos |
],nucleus |
R2361 |
T2543 |
T2544 |
advmod |
first,demonstrated |
R2362 |
T2683 |
T2652 |
punct |
.,shown |
R2363 |
T2684 |
T2685 |
nsubj |
Corticosteroids,are |
R2364 |
T2685 |
T2685 |
ROOT |
are,are |
R2365 |
T2686 |
T2687 |
advmod |
highly,effective |
R2366 |
T2544 |
T2544 |
ROOT |
demonstrated,demonstrated |
R2367 |
T2687 |
T2685 |
acomp |
effective,are |
R2368 |
T2688 |
T2687 |
prep |
in,effective |
R2369 |
T2689 |
T2690 |
det |
the,treatment |
R2370 |
T2545 |
T2544 |
prep |
in,demonstrated |
R2371 |
T2690 |
T2688 |
pobj |
treatment,in |
R2372 |
T2691 |
T2690 |
prep |
of,treatment |
R2373 |
T2546 |
T2547 |
compound |
murine,T |
R2374 |
T2692 |
T2693 |
amod |
allergic,inflammation |
R2375 |
T2693 |
T2691 |
pobj |
inflammation,of |
R2376 |
T2694 |
T2685 |
punct |
",",are |
R2377 |
T2695 |
T2685 |
prep |
with,are |
R2378 |
T2696 |
T2697 |
amod |
marked,suppression |
R2379 |
T2697 |
T2695 |
pobj |
suppression,with |
R2380 |
T2547 |
T2548 |
compound |
T,cells |
R2381 |
T2698 |
T2697 |
prep |
of,suppression |
R2382 |
T2699 |
T2700 |
amod |
Th2,cytokines |
R2383 |
T2700 |
T2698 |
pobj |
cytokines,of |
R2384 |
T2701 |
T2697 |
prep |
in,suppression |
R2385 |
T2548 |
T2545 |
pobj |
cells,in |
R2386 |
T2702 |
T2701 |
pobj |
airways,in |
R2387 |
T2703 |
T2702 |
prep |
of,airways |
R2388 |
T2704 |
T2703 |
pobj |
patients,of |
R2389 |
T2549 |
T2551 |
nmod |
[,] |
R2390 |
T2705 |
T2704 |
prep |
with,patients |
R2391 |
T2706 |
T2705 |
pobj |
asthma,with |
R2392 |
T2707 |
T2709 |
quantmod |
[,] |
R2393 |
T2550 |
T2551 |
nummod |
13,] |
R2394 |
T2708 |
T2709 |
nummod |
16,] |
R2395 |
T2709 |
T2685 |
npadvmod |
],are |
R2396 |
T2710 |
T2685 |
punct |
.,are |
R2397 |
T2711 |
T2712 |
nsubj |
Corticosteroids,mediate |
R2398 |
T2551 |
T2548 |
appos |
],cells |
R2399 |
T2712 |
T2712 |
ROOT |
mediate,mediate |
R2400 |
T2713 |
T2715 |
poss |
their,effects |
R2401 |
T2552 |
T2544 |
cc |
and,demonstrated |
R2402 |
T2714 |
T2715 |
amod |
anti-inflammatory,effects |
R2403 |
T2747 |
T2745 |
pobj |
genes,of |
R2404 |
T2715 |
T2712 |
dobj |
effects,mediate |
R2405 |
T2716 |
T2712 |
prep |
through,mediate |
R2406 |
T2748 |
T2712 |
punct |
.,mediate |
R2407 |
T2717 |
T2716 |
amod |
binding,through |
R2408 |
T2749 |
T2751 |
advmod |
Alternatively,activated |
R2409 |
T2718 |
T2717 |
prep |
to,binding |
R2410 |
T2750 |
T2751 |
punct |
",",activated |
R2411 |
T2719 |
T2720 |
amod |
glucocorticoid,receptors |
R2412 |
T2751 |
T2751 |
ROOT |
activated,activated |
R2413 |
T2752 |
T2753 |
compound |
GR,interacts |
R2414 |
T2720 |
T2718 |
pobj |
receptors,to |
R2415 |
T2721 |
T2720 |
punct |
(,receptors |
R2416 |
T2722 |
T2720 |
appos |
GRs,receptors |
R2417 |
T2753 |
T2751 |
dobj |
interacts,activated |
R2418 |
T2723 |
T2720 |
punct |
),receptors |
R2419 |
T2724 |
T2720 |
punct |
",",receptors |
R2420 |
T2725 |
T2727 |
nsubj |
which,translocate |
R2421 |
T2754 |
T2753 |
prep |
with,interacts |
R2422 |
T2726 |
T2727 |
advmod |
then,translocate |
R2423 |
T2727 |
T2720 |
relcl |
translocate,receptors |
R2424 |
T2755 |
T2756 |
compound |
coactivator,molecules |
R2425 |
T2728 |
T2727 |
prep |
to,translocate |
R2426 |
T2729 |
T2730 |
det |
the,nucleus |
R2427 |
T2730 |
T2728 |
pobj |
nucleus,to |
R2428 |
T2756 |
T2754 |
pobj |
molecules,with |
R2429 |
T2731 |
T2733 |
advmod |
where,interact |
R2430 |
T2757 |
T2758 |
aux |
to,suppress |
R2431 |
T2732 |
T2733 |
nsubj |
they,interact |
R2432 |
T2733 |
T2730 |
relcl |
interact,nucleus |
R2433 |
T2734 |
T2733 |
prep |
with,interact |
R2434 |
T2758 |
T2751 |
advcl |
suppress,activated |
R2435 |
T2735 |
T2737 |
amod |
glucocorticoid,elements |
R2436 |
T2736 |
T2737 |
compound |
response,elements |
R2437 |
T2737 |
T2734 |
pobj |
elements,with |
R2438 |
T2759 |
T2760 |
det |
the,expression |
R2439 |
T2738 |
T2739 |
punct |
(,GREs |
R2440 |
T2760 |
T2758 |
dobj |
expression,suppress |
R2441 |
T2739 |
T2737 |
appos |
GREs,elements |
R2442 |
T2740 |
T2737 |
punct |
),elements |
R2443 |
T2761 |
T2760 |
prep |
of,expression |
R2444 |
T2741 |
T2733 |
prep |
in,interact |
R2445 |
T2742 |
T2744 |
det |
the,regions |
R2446 |
T2743 |
T2744 |
compound |
promoter,regions |
R2447 |
T2762 |
T2763 |
amod |
inflammatory,genes |
R2448 |
T2744 |
T2741 |
pobj |
regions,in |
R2449 |
T2745 |
T2744 |
prep |
of,regions |
R2450 |
T2746 |
T2747 |
amod |
steroid-sensitive,genes |
R2451 |
T2763 |
T2761 |
pobj |
genes,of |
R2452 |
T2764 |
T2758 |
prep |
by,suppress |
R2453 |
T2765 |
T2764 |
pcomp |
inhibiting,by |
R2454 |
T2766 |
T2767 |
det |
the,action |
R2455 |
T2844 |
T2841 |
appos |
],pathway |
R2456 |
T2767 |
T2765 |
dobj |
action,inhibiting |
R2457 |
T2845 |
T2820 |
punct |
.,signals |
R2458 |
T2846 |
T2856 |
nsubj |
NL1,binds |
R2459 |
T2768 |
T2767 |
prep |
of,action |
R2460 |
T2847 |
T2846 |
punct |
",",NL1 |
R2461 |
T2848 |
T2849 |
nsubj |
which,is |
R2462 |
T2849 |
T2846 |
relcl |
is,NL1 |
R2463 |
T2769 |
T2771 |
amod |
proinflammatory,factors |
R2464 |
T2850 |
T2849 |
acomp |
similar,is |
R2465 |
T2851 |
T2850 |
prep |
to,similar |
R2466 |
T2852 |
T2854 |
det |
the,NLS |
R2467 |
T2770 |
T2771 |
compound |
transcription,factors |
R2468 |
T2853 |
T2854 |
compound |
SV40,NLS |
R2469 |
T2854 |
T2851 |
pobj |
NLS,to |
R2470 |
T2855 |
T2849 |
punct |
",",is |
R2471 |
T2771 |
T2768 |
pobj |
factors,of |
R2472 |
T2856 |
T2856 |
ROOT |
binds,binds |
R2473 |
T2857 |
T2858 |
aux |
to,importin-α |
R2474 |
T2858 |
T2856 |
xcomp |
importin-α,binds |
R2475 |
T2772 |
T2773 |
amod |
such,as |
R2476 |
T2859 |
T2858 |
dobj |
[,importin-α |
R2477 |
T2860 |
T2861 |
nummod |
22,] |
R2478 |
T2861 |
T2856 |
npadvmod |
],binds |
R2479 |
T2862 |
T2856 |
punct |
.,binds |
R2480 |
T2863 |
T2865 |
nsubjpass |
NL1,activated |
R2481 |
T2864 |
T2865 |
auxpass |
is,activated |
R2482 |
T2773 |
T2771 |
prep |
as,factors |
R2483 |
T2865 |
T2865 |
ROOT |
activated,activated |
R2484 |
T2866 |
T2867 |
advmod |
both,by |
R2485 |
T2867 |
T2865 |
agent |
by,activated |
R2486 |
T2868 |
T2869 |
amod |
glucocorticoid,agonists |
R2487 |
T2774 |
T2775 |
amod |
nuclear,factor-κB |
R2488 |
T2869 |
T2867 |
pobj |
agonists,by |
R2489 |
T2775 |
T2773 |
pobj |
factor-κB,as |
R2490 |
T2870 |
T2871 |
amod |
such,as |
R2491 |
T2871 |
T2869 |
prep |
as,agonists |
R2492 |
T2872 |
T2871 |
pobj |
dexamethasone,as |
R2493 |
T2873 |
T2872 |
cc |
and,dexamethasone |
R2494 |
T2776 |
T2775 |
punct |
(,factor-κB |
R2495 |
T2874 |
T2875 |
compound |
fluticasone,propionate |
R2496 |
T2875 |
T2872 |
conj |
propionate,dexamethasone |
R2497 |
T2876 |
T2877 |
punct |
(,FP |
R2498 |
T2877 |
T2875 |
appos |
FP,propionate |
R2499 |
T2777 |
T2775 |
appos |
NF-κB,factor-κB |
R2500 |
T2878 |
T2877 |
punct |
),FP |
R2501 |
T2879 |
T2867 |
cc |
and,by |
R2502 |
T2880 |
T2867 |
conj |
by,by |
R2503 |
T2778 |
T2775 |
punct |
),factor-κB |
R2504 |
T2779 |
T2765 |
prep |
through,inhibiting |
R2505 |
T2881 |
T2882 |
amod |
glucocorticoid,antagonists |
R2506 |
T2780 |
T2781 |
det |
the,recruitment |
R2507 |
T2781 |
T2779 |
pobj |
recruitment,through |
R2508 |
T2882 |
T2880 |
pobj |
antagonists,by |
R2509 |
T2782 |
T2781 |
prep |
of,recruitment |
R2510 |
T2883 |
T2884 |
amod |
such,as |
R2511 |
T2783 |
T2784 |
compound |
co-repressor,molecules |
R2512 |
T2784 |
T2782 |
pobj |
molecules,of |
R2513 |
T2884 |
T2882 |
prep |
as,antagonists |
R2514 |
T2885 |
T2884 |
pobj |
mifepristone,as |
R2515 |
T2785 |
T2786 |
amod |
such,as |
R2516 |
T2886 |
T2885 |
punct |
(,mifepristone |
R2517 |
T2887 |
T2889 |
nmod |
RU486,[ |
R2518 |
T2888 |
T2889 |
punct |
),[ |
R2519 |
T2786 |
T2784 |
prep |
as,molecules |
R2520 |
T2889 |
T2865 |
npadvmod |
[,activated |
R2521 |
T2890 |
T2891 |
nummod |
23,] |
R2522 |
T2891 |
T2889 |
appos |
],[ |
R2523 |
T2787 |
T2789 |
compound |
histone,[ |
R2524 |
T2892 |
T2865 |
punct |
.,activated |
R2525 |
T2893 |
T2896 |
nsubjpass |
NL1,mutated |
R2526 |
T2788 |
T2789 |
compound |
deacetylase-2,[ |
R2527 |
T2894 |
T2896 |
aux |
can,mutated |
R2528 |
T2789 |
T2786 |
pobj |
[,as |
R2529 |
T2895 |
T2896 |
auxpass |
be,mutated |
R2530 |
T2896 |
T2896 |
ROOT |
mutated,mutated |
R2531 |
T2790 |
T2791 |
nummod |
17,] |
R2532 |
T2897 |
T2896 |
punct |
",",mutated |
R2533 |
T2898 |
T2896 |
cc |
and,mutated |
R2534 |
T2899 |
T2901 |
det |
the,GR |
R2535 |
T2791 |
T2789 |
conj |
],[ |
R2536 |
T2900 |
T2901 |
amod |
resulting,GR |
R2537 |
T2901 |
T2903 |
nsubj |
GR,translocates |
R2538 |
T2902 |
T2903 |
advmod |
still,translocates |
R2539 |
T2792 |
T2791 |
punct |
",",] |
R2540 |
T2903 |
T2896 |
conj |
translocates,mutated |
R2541 |
T2904 |
T2903 |
prep |
to,translocates |
R2542 |
T2905 |
T2906 |
det |
the,nucleus |
R2543 |
T2793 |
T2791 |
conj |
[,] |
R2544 |
T2906 |
T2904 |
pobj |
nucleus,to |
R2545 |
T2907 |
T2903 |
prep |
in,translocates |
R2546 |
T2908 |
T2907 |
pobj |
response,in |
R2547 |
T2794 |
T2795 |
nummod |
18,] |
R2548 |
T2909 |
T2908 |
prep |
to,response |
R2549 |
T2910 |
T2909 |
pobj |
ligands,to |
R2550 |
T2911 |
T2903 |
punct |
",",translocates |
R2551 |
T2795 |
T2791 |
conj |
],] |
R2552 |
T2912 |
T2903 |
cc |
but,translocates |
R2553 |
T2913 |
T2903 |
conj |
via,translocates |
R2554 |
T2914 |
T2913 |
pobj |
interaction,via |
R2555 |
T2796 |
T2751 |
punct |
.,activated |
R2556 |
T2915 |
T2914 |
prep |
with,interaction |
R2557 |
T2916 |
T2915 |
pobj |
importin,with |
R2558 |
T2917 |
T2916 |
nummod |
7,importin |
R2559 |
T2797 |
T2798 |
compound |
Nuclear,localisation |
R2560 |
T2918 |
T2916 |
punct |
",",importin |
R2561 |
T2919 |
T2920 |
det |
an,event |
R2562 |
T2920 |
T2916 |
appos |
event,importin |
R2563 |
T2798 |
T2804 |
nsubjpass |
localisation,mediated |
R2564 |
T2921 |
T2922 |
nsubj |
that,requires |
R2565 |
T2922 |
T2920 |
relcl |
requires,event |
R2566 |
T2923 |
T2926 |
det |
an,component |
R2567 |
T2799 |
T2798 |
cc |
and,localisation |
R2568 |
T2924 |
T2925 |
advmod |
as-yet,unknown |
R2569 |
T2925 |
T2926 |
amod |
unknown,component |
R2570 |
T2926 |
T2922 |
dobj |
component,requires |
R2571 |
T2800 |
T2798 |
conj |
retention,localisation |
R2572 |
T2927 |
T2926 |
appos |
[,component |
R2573 |
T2801 |
T2800 |
prep |
of,retention |
R2574 |
T2928 |
T2929 |
nummod |
23,] |
R2575 |
T2929 |
T2922 |
dobj |
],requires |
R2576 |
T2802 |
T2801 |
pobj |
GR,of |
R2577 |
T2930 |
T2903 |
punct |
.,translocates |
R2578 |
T2931 |
T2934 |
nsubjpass |
NL2,defined |
R2579 |
T2932 |
T2934 |
auxpass |
is,defined |
R2580 |
T2933 |
T2934 |
advmod |
poorly,defined |
R2581 |
T2934 |
T2934 |
ROOT |
defined,defined |
R2582 |
T2935 |
T2934 |
punct |
",",defined |
R2583 |
T2803 |
T2804 |
auxpass |
is,mediated |
R2584 |
T2936 |
T2934 |
advcl |
residing,defined |
R2585 |
T2937 |
T2936 |
prep |
in,residing |
R2586 |
T2938 |
T2940 |
det |
the,domain |
R2587 |
T2804 |
T2820 |
ccomp |
mediated,signals |
R2588 |
T2939 |
T2940 |
amod |
ligand-binding,domain |
R2589 |
T2940 |
T2937 |
pobj |
domain,in |
R2590 |
T2805 |
T2804 |
prep |
through,mediated |
R2591 |
T2806 |
T2809 |
det |
the,sequences |
R2592 |
T2807 |
T2808 |
amod |
nuclear,localisation |
R2593 |
T2941 |
T2934 |
punct |
",",defined |
R2594 |
T2808 |
T2809 |
compound |
localisation,sequences |
R2595 |
T2942 |
T2934 |
cc |
and,defined |
R2596 |
T2943 |
T2944 |
advmod |
much,less |
R2597 |
T2944 |
T2946 |
advmod |
less,known |
R2598 |
T2809 |
T2805 |
pobj |
sequences,through |
R2599 |
T2945 |
T2946 |
auxpass |
is,known |
R2600 |
T2946 |
T2934 |
conj |
known,defined |
R2601 |
T2947 |
T2946 |
prep |
about,known |
R2602 |
T2810 |
T2809 |
appos |
NL1,sequences |
R2603 |
T2948 |
T2949 |
poss |
its,mechanism |
R2604 |
T2949 |
T2947 |
pobj |
mechanism,about |
R2605 |
T2950 |
T2949 |
prep |
of,mechanism |
R2606 |
T2811 |
T2810 |
cc |
and,NL1 |
R2607 |
T2951 |
T2953 |
compound |
GR,[ |
R2608 |
T2952 |
T2953 |
compound |
import,[ |
R2609 |
T2953 |
T2950 |
pobj |
[,of |
R2610 |
T2812 |
T2813 |
compound |
NL2,[ |
R2611 |
T2954 |
T2955 |
nummod |
24,] |
R2612 |
T2955 |
T2949 |
appos |
],mechanism |
R2613 |
T2956 |
T2934 |
punct |
.,defined |
R2614 |
T2813 |
T2810 |
conj |
[,NL1 |
R2615 |
T2957 |
T2958 |
det |
A,variety |
R2616 |
T2958 |
T2962 |
nsubj |
variety,are |
R2617 |
T2959 |
T2958 |
prep |
of,variety |
R2618 |
T2814 |
T2815 |
nummod |
19,] |
R2619 |
T2960 |
T2961 |
amod |
other,factors |
R2620 |
T2961 |
T2959 |
pobj |
factors,of |
R2621 |
T2962 |
T2962 |
ROOT |
are,are |
R2622 |
T2815 |
T2810 |
conj |
],NL1 |
R2623 |
T2963 |
T2962 |
advmod |
also,are |
R2624 |
T2964 |
T2962 |
acomp |
important,are |
R2625 |
T2965 |
T2964 |
prep |
for,important |
R2626 |
T2816 |
T2804 |
punct |
",",mediated |
R2627 |
T2966 |
T2967 |
det |
the,regulation |
R2628 |
T2967 |
T2965 |
pobj |
regulation,for |
R2629 |
T2968 |
T2967 |
prep |
of,regulation |
R2630 |
T2969 |
T2970 |
compound |
GR,activation |
R2631 |
T2970 |
T2968 |
pobj |
activation,of |
R2632 |
T2817 |
T2804 |
agent |
by,mediated |
R2633 |
T2971 |
T2970 |
cc |
and,activation |
R2634 |
T2818 |
T2819 |
amod |
nuclear,retention |
R2635 |
T2972 |
T2973 |
amod |
nuclear,import |
R2636 |
T2819 |
T2817 |
pobj |
retention,by |
R2637 |
T2973 |
T2970 |
conj |
import,activation |
R2638 |
T2974 |
T2967 |
prep |
including,regulation |
R2639 |
T2975 |
T2974 |
pobj |
chaperones,including |
R2640 |
T2820 |
T2820 |
ROOT |
signals,signals |
R2641 |
T2976 |
T2977 |
amod |
such,as |
R2642 |
T2821 |
T2823 |
nmod |
[,] |
R2643 |
T2822 |
T2823 |
nummod |
20,] |
R2644 |
T2977 |
T2975 |
prep |
as,chaperones |
R2645 |
T2823 |
T2820 |
dobj |
],signals |
R2646 |
T2824 |
T2820 |
punct |
",",signals |
R2647 |
T2978 |
T2990 |
nmod |
Hsp90,proteins |
R2648 |
T2825 |
T2820 |
cc |
and,signals |
R2649 |
T2979 |
T2978 |
cc |
and,Hsp90 |
R2650 |
T2826 |
T2820 |
conj |
by,signals |
R2651 |
T2827 |
T2826 |
pobj |
control,by |
R2652 |
T2980 |
T2981 |
amod |
other,immunophilins |
R2653 |
T2828 |
T2827 |
prep |
of,control |
R2654 |
T2981 |
T2978 |
conj |
immunophilins,Hsp90 |
R2655 |
T2829 |
T2830 |
amod |
nuclear,export |
R2656 |
T2982 |
T2978 |
conj |
[,Hsp90 |
R2657 |
T2830 |
T2828 |
pobj |
export,of |
R2658 |
T2983 |
T2984 |
nummod |
24,] |
R2659 |
T2984 |
T2978 |
conj |
],Hsp90 |
R2660 |
T2831 |
T2820 |
prep |
via,signals |
R2661 |
T2985 |
T2978 |
conj |
[,Hsp90 |
R2662 |
T2986 |
T2987 |
nummod |
26,] |
R2663 |
T2832 |
T2841 |
det |
a,pathway |
R2664 |
T2987 |
T2990 |
nmod |
],proteins |
R2665 |
T2988 |
T2987 |
cc |
and,] |
R2666 |
T2989 |
T2990 |
amod |
FK506-binding,proteins |
R2667 |
T2833 |
T2834 |
amod |
chromosomal,region |
R2668 |
T2990 |
T2977 |
pobj |
proteins,as |
R2669 |
T2991 |
T2994 |
nsubjpass |
that,linked |
R2670 |
T2992 |
T2994 |
aux |
may,linked |
R2671 |
T2834 |
T2835 |
compound |
region,maintenance |
R2672 |
T2993 |
T2994 |
auxpass |
be,linked |
R2673 |
T2994 |
T2990 |
relcl |
linked,proteins |
R2674 |
T2995 |
T2996 |
aux |
to,dynein |
R2675 |
T2996 |
T2994 |
xcomp |
dynein,linked |
R2676 |
T2835 |
T2841 |
nmod |
maintenance,pathway |
R2677 |
T2997 |
T2996 |
cc |
and/or,dynein |
R2678 |
T2998 |
T2996 |
conj |
peptidylprolyl,dynein |
R2679 |
T2999 |
T3000 |
compound |
isomerase,[ |
R2680 |
T3000 |
T2998 |
dobj |
[,peptidylprolyl |
R2681 |
T3001 |
T3002 |
nummod |
27,] |
R2682 |
T3002 |
T2998 |
npadvmod |
],peptidylprolyl |
R2683 |
T2836 |
T2835 |
nummod |
1,maintenance |
R2684 |
T3003 |
T3002 |
punct |
",",] |
R2685 |
T3004 |
T3002 |
appos |
[,] |
R2686 |
T3005 |
T3006 |
nummod |
28,] |
R2687 |
T2837 |
T2835 |
punct |
(,maintenance |
R2688 |
T3006 |
T3002 |
appos |
],] |
R2689 |
T3007 |
T2962 |
punct |
.,are |
R2690 |
T3008 |
T3021 |
advmod |
However,is |
R2691 |
T2838 |
T2835 |
appos |
CRM-1,maintenance |
R2692 |
T3009 |
T3021 |
punct |
",",is |
R2693 |
T3010 |
T3012 |
det |
the,basis |
R2694 |
T3011 |
T3012 |
amod |
molecular,basis |
R2695 |
T2839 |
T2835 |
punct |
),maintenance |
R2696 |
T3012 |
T3021 |
nsubj |
basis,is |
R2697 |
T3013 |
T3012 |
prep |
for,basis |
R2698 |
T2840 |
T2841 |
amod |
dependent,pathway |
R2699 |
T3014 |
T3015 |
det |
the,inhibition |
R2700 |
T3015 |
T3013 |
pobj |
inhibition,for |
R2701 |
T2841 |
T2831 |
pobj |
pathway,via |
R2702 |
T2842 |
T2844 |
nmod |
[,] |
R2703 |
T3016 |
T3015 |
prep |
of,inhibition |
R2704 |
T2843 |
T2844 |
nummod |
21,] |
R2705 |
T3017 |
T3018 |
amod |
Th2,cytokines |
R2706 |
T3018 |
T3016 |
pobj |
cytokines,of |
R2707 |
T3038 |
T3021 |
advcl |
have,is |
R2708 |
T3019 |
T3015 |
prep |
by,inhibition |
R2709 |
T3020 |
T3019 |
pobj |
corticosteroids,by |
R2710 |
T3021 |
T3021 |
ROOT |
is,is |
R2711 |
T3022 |
T3021 |
neg |
not,is |
R2712 |
T3039 |
T3042 |
det |
any,sequence |
R2713 |
T3023 |
T3024 |
advmod |
well,understood |
R2714 |
T3024 |
T3021 |
acomp |
understood,is |
R2715 |
T3040 |
T3042 |
amod |
recognisable,sequence |
R2716 |
T3025 |
T3021 |
punct |
",",is |
R2717 |
T3026 |
T3038 |
mark |
because,have |
R2718 |
T3027 |
T3028 |
det |
the,genes |
R2719 |
T3041 |
T3042 |
compound |
GRE,sequence |
R2720 |
T3028 |
T3038 |
nsubj |
genes,have |
R2721 |
T3029 |
T3028 |
acl |
encoding,genes |
R2722 |
T3030 |
T3029 |
dobj |
IL-4,encoding |
R2723 |
T3042 |
T3038 |
dobj |
sequence,have |
R2724 |
T3031 |
T3030 |
punct |
",",IL-4 |
R2725 |
T3032 |
T3030 |
conj |
IL-5,IL-4 |
R2726 |
T3033 |
T3032 |
punct |
",",IL-5 |
R2727 |
T3043 |
T3045 |
nmod |
[,] |
R2728 |
T3034 |
T3029 |
cc |
and,encoding |
R2729 |
T3035 |
T3038 |
nsubj |
IL-13,have |
R2730 |
T3036 |
T3038 |
aux |
do,have |
R2731 |
T3037 |
T3038 |
neg |
not,have |
R2732 |
T3044 |
T3045 |
nummod |
29,] |
R2733 |
T3045 |
T3042 |
appos |
],sequence |
R2734 |
T3046 |
T3038 |
cc |
and,have |
R2735 |
T3047 |
T3050 |
auxpass |
are,regulated |
R2736 |
T3048 |
T3050 |
advmod |
only,regulated |
R2737 |
T3135 |
T3133 |
dobj |
effects,investigated |
R2738 |
T3049 |
T3050 |
advmod |
partly,regulated |
R2739 |
T3136 |
T3135 |
prep |
of,effects |
R2740 |
T3137 |
T3139 |
det |
a,corticosteroid |
R2741 |
T3050 |
T3038 |
conj |
regulated,have |
R2742 |
T3138 |
T3139 |
amod |
synthetic,corticosteroid |
R2743 |
T3139 |
T3136 |
pobj |
corticosteroid,of |
R2744 |
T3140 |
T3139 |
punct |
",",corticosteroid |
R2745 |
T3051 |
T3050 |
agent |
by,regulated |
R2746 |
T3141 |
T3139 |
appos |
FP,corticosteroid |
R2747 |
T3142 |
T3139 |
punct |
",",corticosteroid |
R2748 |
T3143 |
T3135 |
prep |
on,effects |
R2749 |
T3144 |
T3145 |
amod |
GATA-3,phosphorylation |
R2750 |
T3052 |
T3051 |
pobj |
NF-κB,by |
R2751 |
T3145 |
T3143 |
pobj |
phosphorylation,on |
R2752 |
T3146 |
T3145 |
cc |
and,phosphorylation |
R2753 |
T3053 |
T3050 |
prep |
in,regulated |
R2754 |
T3147 |
T3148 |
amod |
nuclear,translocation |
R2755 |
T3148 |
T3145 |
conj |
translocation,phosphorylation |
R2756 |
T3149 |
T3135 |
prep |
in,effects |
R2757 |
T3150 |
T3154 |
det |
a,line |
R2758 |
T3054 |
T3055 |
amod |
human,cells |
R2759 |
T3151 |
T3154 |
compound |
T,line |
R2760 |
T3152 |
T3154 |
compound |
lymphocyte,line |
R2761 |
T3153 |
T3154 |
compound |
cell,line |
R2762 |
T3055 |
T3053 |
pobj |
cells,in |
R2763 |
T3154 |
T3149 |
pobj |
line,in |
R2764 |
T3155 |
T3156 |
punct |
(,HuT-78 |
R2765 |
T3056 |
T3058 |
nmod |
[,] |
R2766 |
T3156 |
T3154 |
appos |
HuT-78,line |
R2767 |
T3157 |
T3156 |
punct |
),HuT-78 |
R2768 |
T3158 |
T3149 |
cc |
and,in |
R2769 |
T3057 |
T3058 |
nummod |
30,] |
R2770 |
T3159 |
T3149 |
conj |
in,in |
R2771 |
T3160 |
T3163 |
amod |
peripheral,cells |
R2772 |
T3161 |
T3162 |
compound |
blood,mononuclear |
R2773 |
T3058 |
T3055 |
appos |
],cells |
R2774 |
T3162 |
T3163 |
compound |
mononuclear,cells |
R2775 |
T3163 |
T3159 |
pobj |
cells,in |
R2776 |
T3059 |
T3055 |
appos |
[,cells |
R2777 |
T3164 |
T3163 |
acl |
activated,cells |
R2778 |
T3165 |
T3164 |
agent |
by,activated |
R2779 |
T3166 |
T3169 |
amod |
anti-CD3,antibodies |
R2780 |
T3167 |
T3166 |
cc |
and,anti-CD3 |
R2781 |
T3168 |
T3166 |
conj |
anti-CD28,anti-CD3 |
R2782 |
T3169 |
T3165 |
pobj |
antibodies,by |
R2783 |
T3060 |
T3061 |
nummod |
32,] |
R2784 |
T3170 |
T3164 |
prep |
in,activated |
R2785 |
T3171 |
T3170 |
pobj |
vitro,in |
R2786 |
T3172 |
T3133 |
punct |
.,investigated |
R2787 |
T3061 |
T3059 |
appos |
],[ |
R2788 |
T3173 |
T3175 |
nsubj |
We,studied |
R2789 |
T3174 |
T3175 |
advmod |
also,studied |
R2790 |
T3175 |
T3175 |
ROOT |
studied,studied |
R2791 |
T3062 |
T3021 |
punct |
.,is |
R2792 |
T3063 |
T3076 |
advcl |
Using,shown |
R2793 |
T3176 |
T3177 |
det |
the,effects |
R2794 |
T3064 |
T3063 |
dobj |
overexpression,Using |
R2795 |
T3177 |
T3175 |
dobj |
effects,studied |
R2796 |
T3178 |
T3177 |
prep |
of,effects |
R2797 |
T3065 |
T3064 |
cc |
and,overexpression |
R2798 |
T3179 |
T3181 |
amod |
inhaled,therapy |
R2799 |
T3180 |
T3181 |
compound |
fluticasone,therapy |
R2800 |
T3181 |
T3178 |
pobj |
therapy,of |
R2801 |
T3066 |
T3067 |
amod |
CAT-reporter,genes |
R2802 |
T3182 |
T3181 |
prep |
on,therapy |
R2803 |
T3183 |
T3185 |
amod |
GATA-3,localization |
R2804 |
T3184 |
T3185 |
amod |
subcellular,localization |
R2805 |
T3067 |
T3064 |
conj |
genes,overexpression |
R2806 |
T3185 |
T3182 |
pobj |
localization,on |
R2807 |
T3186 |
T3185 |
prep |
in,localization |
R2808 |
T3187 |
T3190 |
amod |
peripheral,cells |
R2809 |
T3068 |
T3067 |
punct |
",",genes |
R2810 |
T3188 |
T3189 |
compound |
blood,mononuclear |
R2811 |
T3189 |
T3190 |
compound |
mononuclear,cells |
R2812 |
T3190 |
T3186 |
pobj |
cells,in |
R2813 |
T3069 |
T3076 |
nsubj |
Lavender,shown |
R2814 |
T3191 |
T3192 |
punct |
(,PBMCs |
R2815 |
T3192 |
T3190 |
appos |
PBMCs,cells |
R2816 |
T3193 |
T3192 |
punct |
),PBMCs |
R2817 |
T3070 |
T3069 |
cc |
and,Lavender |
R2818 |
T3194 |
T3192 |
prep |
from,PBMCs |
R2819 |
T3195 |
T3194 |
pobj |
patients,from |
R2820 |
T3196 |
T3192 |
prep |
with,PBMCs |
R2821 |
T3071 |
T3069 |
conj |
colleagues,Lavender |
R2822 |
T3197 |
T3196 |
pobj |
asthma,with |
R2823 |
T3198 |
T3175 |
punct |
.,studied |
R2824 |
T3072 |
T3074 |
nmod |
[,] |
R2825 |
T3073 |
T3074 |
nummod |
33,] |
R2826 |
T3074 |
T3071 |
appos |
],colleagues |
R2827 |
T3075 |
T3076 |
aux |
have,shown |
R2828 |
T3076 |
T3076 |
ROOT |
shown,shown |
R2829 |
T3077 |
T3079 |
mark |
that,reduced |
R2830 |
T3078 |
T3079 |
nsubj |
GR,reduced |
R2831 |
T3079 |
T3076 |
ccomp |
reduced,shown |
R2832 |
T3080 |
T3081 |
amod |
GATA-3-mediated,IL-5 |
R2833 |
T3081 |
T3079 |
dobj |
IL-5,reduced |
R2834 |
T3082 |
T3079 |
cc |
and,reduced |
R2835 |
T3083 |
T3085 |
nummod |
-13,activity |
R2836 |
T3084 |
T3085 |
compound |
promoter,activity |
R2837 |
T3085 |
T3079 |
conj |
activity,reduced |
R2838 |
T3086 |
T3085 |
prep |
in,activity |
R2839 |
T3087 |
T3091 |
amod |
human,cells |
R2840 |
T3088 |
T3091 |
compound |
CD4,cells |
R2841 |
T3089 |
T3091 |
nummod |
+,cells |
R2842 |
T3090 |
T3091 |
compound |
T,cells |
R2843 |
T3091 |
T3086 |
pobj |
cells,in |
R2844 |
T3092 |
T3076 |
punct |
.,shown |
R2845 |
T3093 |
T3094 |
det |
The,authors |
R2846 |
T3094 |
T3095 |
nsubj |
authors,postulated |
R2847 |
T3095 |
T3095 |
ROOT |
postulated,postulated |
R2848 |
T3096 |
T3102 |
mark |
that,alter |
R2849 |
T3097 |
T3098 |
amod |
local,recruitment |
R2850 |
T3098 |
T3102 |
nsubj |
recruitment,alter |
R2851 |
T3099 |
T3098 |
prep |
of,recruitment |
R2852 |
T3100 |
T3099 |
pobj |
GR,of |
R2853 |
T3101 |
T3102 |
aux |
may,alter |
R2854 |
T3102 |
T3095 |
ccomp |
alter,postulated |
R2855 |
T3103 |
T3104 |
det |
the,ability |
R2856 |
T3104 |
T3102 |
dobj |
ability,alter |
R2857 |
T3105 |
T3104 |
prep |
of,ability |
R2858 |
T3106 |
T3105 |
pobj |
GATA-3,of |
R2859 |
T3107 |
T3109 |
preconj |
either,bind |
R2860 |
T3108 |
T3109 |
aux |
to,bind |
R2861 |
T3109 |
T3104 |
conj |
bind,ability |
R2862 |
T3110 |
T3102 |
prep |
to,alter |
R2863 |
T3111 |
T3113 |
poss |
its,site |
R2864 |
T3112 |
T3113 |
compound |
target,site |
R2865 |
T3113 |
T3110 |
pobj |
site,to |
R2866 |
T3114 |
T3102 |
punct |
",",alter |
R2867 |
T3115 |
T3116 |
aux |
to,cause |
R2868 |
T3116 |
T3102 |
advcl |
cause,alter |
R2869 |
T3117 |
T3118 |
amod |
transcriptional,up-regulation |
R2870 |
T3118 |
T3116 |
dobj |
up-regulation,cause |
R2871 |
T3119 |
T3118 |
punct |
",",up-regulation |
R2872 |
T3120 |
T3116 |
cc |
or,cause |
R2873 |
T3121 |
T3122 |
aux |
to,maintain |
R2874 |
T3122 |
T3116 |
conj |
maintain,cause |
R2875 |
T3123 |
T3124 |
det |
an,environment |
R2876 |
T3124 |
T3122 |
dobj |
environment,maintain |
R2877 |
T3125 |
T3126 |
nsubj |
that,is |
R2878 |
T3126 |
T3124 |
relcl |
is,environment |
R2879 |
T3127 |
T3126 |
acomp |
permissive,is |
R2880 |
T3128 |
T3127 |
prep |
for,permissive |
R2881 |
T3129 |
T3128 |
pobj |
transcription,for |
R2882 |
T3130 |
T3095 |
punct |
.,postulated |
R2883 |
T3131 |
T3133 |
nsubj |
We,investigated |
R2884 |
T3132 |
T3133 |
advmod |
therefore,investigated |
R2885 |
T3133 |
T3133 |
ROOT |
investigated,investigated |
R2886 |
T3134 |
T3135 |
det |
the,effects |
R3292 |
T3810 |
T3815 |
npadvmod |
Participants,studied |
R3293 |
T3811 |
T3810 |
cc |
and,Participants |
R3294 |
T3812 |
T3813 |
compound |
Study,Design |
R3295 |
T3813 |
T3810 |
conj |
Design,Participants |
R3296 |
T3814 |
T3815 |
nsubj |
We,studied |
R3297 |
T3815 |
T3815 |
ROOT |
studied,studied |
R3298 |
T3816 |
T3815 |
dobj |
patients,studied |
R3299 |
T3817 |
T3816 |
prep |
with,patients |
R3300 |
T3818 |
T3819 |
amod |
mild,asthma |
R3301 |
T3819 |
T3817 |
pobj |
asthma,with |
R3302 |
T3820 |
T3823 |
nsubjpass |
who,treated |
R3303 |
T3821 |
T3823 |
auxpass |
were,treated |
R3304 |
T3822 |
T3823 |
neg |
not,treated |
R3305 |
T3823 |
T3816 |
relcl |
treated,patients |
R3306 |
T3824 |
T3823 |
prep |
with,treated |
R3307 |
T3825 |
T3826 |
amod |
inhaled,corticosteroids |
R3308 |
T3826 |
T3824 |
pobj |
corticosteroids,with |
R3309 |
T3827 |
T3830 |
nsubjpass |
who,included |
R3310 |
T3828 |
T3830 |
aux |
had,included |
R3311 |
T3829 |
T3830 |
auxpass |
been,included |
R3312 |
T3830 |
T3826 |
relcl |
included,corticosteroids |
R3313 |
T3831 |
T3830 |
prep |
in,included |
R3314 |
T3832 |
T3840 |
det |
a,study |
R3315 |
T3833 |
T3834 |
advmod |
previously,reported |
R3316 |
T3834 |
T3835 |
amod |
reported,double-blind |
R3317 |
T3835 |
T3840 |
amod |
double-blind,study |
R3318 |
T3836 |
T3840 |
punct |
",",study |
R3319 |
T3837 |
T3840 |
amod |
placebo-controlled,study |
R3320 |
T3838 |
T3840 |
punct |
",",study |
R3321 |
T3839 |
T3840 |
amod |
crossover,study |
R3322 |
T3840 |
T3831 |
pobj |
study,in |
R3323 |
T3841 |
T3840 |
prep |
with,study |
R3324 |
T3842 |
T3843 |
compound |
FP,[ |
R3325 |
T3843 |
T3841 |
pobj |
[,with |
R3326 |
T3844 |
T3845 |
nummod |
34,] |
R3327 |
T3845 |
T3843 |
appos |
],[ |
R3328 |
T3846 |
T3815 |
punct |
.,studied |
R3329 |
T3847 |
T3848 |
nummod |
Seven,patients |
R3330 |
T3848 |
T3852 |
nsubj |
patients,entered |
R3331 |
T3849 |
T3848 |
prep |
with,patients |
R3332 |
T3850 |
T3851 |
amod |
mild,asthma |
R3333 |
T3851 |
T3849 |
pobj |
asthma,with |
R3334 |
T3852 |
T3852 |
ROOT |
entered,entered |
R3335 |
T3853 |
T3854 |
det |
the,study |
R3336 |
T3854 |
T3852 |
dobj |
study,entered |
R3337 |
T3855 |
T3852 |
cc |
and,entered |
R3338 |
T3856 |
T3857 |
auxpass |
were,randomized |
R3339 |
T3857 |
T3852 |
conj |
randomized,entered |
R3340 |
T3858 |
T3859 |
aux |
to,receive |
R3341 |
T3859 |
T3857 |
xcomp |
receive,randomized |
R3342 |
T3860 |
T3862 |
det |
a,inhalation |
R3343 |
T3861 |
T3862 |
amod |
single,inhalation |
R3344 |
T3862 |
T3859 |
dobj |
inhalation,receive |
R3345 |
T3863 |
T3862 |
prep |
of,inhalation |
R3346 |
T3864 |
T3863 |
pobj |
FP,of |
R3347 |
T3865 |
T3864 |
punct |
(,FP |
R3348 |
T3866 |
T3864 |
nummod |
100,FP |
R3349 |
T3867 |
T3864 |
cc |
and,FP |
R3350 |
T3868 |
T3869 |
nummod |
500,µg |
R3351 |
T3869 |
T3864 |
conj |
µg,FP |
R3352 |
T3870 |
T3869 |
punct |
),µg |
R3353 |
T3871 |
T3869 |
cc |
or,µg |
R3354 |
T3872 |
T3875 |
det |
a,control |
R3355 |
T3873 |
T3875 |
amod |
matched,control |
R3356 |
T3874 |
T3875 |
compound |
placebo,control |
R3357 |
T3875 |
T3869 |
conj |
control,µg |
R3358 |
T3876 |
T3859 |
prep |
via,receive |
R3359 |
T3877 |
T3879 |
det |
a,chamber |
R3360 |
T3878 |
T3879 |
compound |
spacer,chamber |
R3361 |
T3879 |
T3876 |
pobj |
chamber,via |
R3362 |
T3880 |
T3857 |
punct |
",",randomized |
R3363 |
T3881 |
T3857 |
cc |
and,randomized |
R3364 |
T3882 |
T3884 |
det |
the,treatment |
R3365 |
T3883 |
T3884 |
amod |
other,treatment |
R3366 |
T3884 |
T3886 |
nsubjpass |
treatment,given |
R3367 |
T3885 |
T3886 |
auxpass |
was,given |
R3368 |
T3886 |
T3857 |
conj |
given,randomized |
R3369 |
T3887 |
T3898 |
mark |
after,taken |
R3370 |
T3888 |
T3890 |
det |
a,period |
R3371 |
T3889 |
T3890 |
amod |
wash-out,period |
R3372 |
T3890 |
T3898 |
nsubjpass |
period,taken |
R3373 |
T3891 |
T3890 |
prep |
of,period |
R3374 |
T3892 |
T3893 |
advmod |
at,least |
R3375 |
T3893 |
T3894 |
advmod |
least,6 |
R3376 |
T3894 |
T3895 |
nummod |
6,d. |
R3377 |
T3895 |
T3896 |
compound |
d.,Blood |
R3378 |
T3896 |
T3891 |
pobj |
Blood,of |
R3379 |
T3897 |
T3898 |
auxpass |
was,taken |
R3380 |
T3898 |
T3886 |
advcl |
taken,given |
R3381 |
T3899 |
T3898 |
prep |
for,taken |
R3382 |
T3900 |
T3899 |
pobj |
preparation,for |
R3383 |
T3901 |
T3900 |
prep |
of,preparation |
R3384 |
T3902 |
T3901 |
pobj |
PBMCs,of |
R3385 |
T3903 |
T3898 |
prep |
at,taken |
R3386 |
T3904 |
T3903 |
pobj |
1,at |
R3387 |
T3905 |
T3898 |
cc |
and,taken |
R3388 |
T3906 |
T3907 |
nummod |
2,h |
R3389 |
T3907 |
T3898 |
conj |
h,taken |
R3390 |
T3908 |
T3907 |
prep |
after,h |
R3391 |
T3909 |
T3910 |
compound |
drug,administration |
R3392 |
T3910 |
T3908 |
pobj |
administration,after |
R3393 |
T3911 |
T3852 |
punct |
.,entered |
R3394 |
T3912 |
T3913 |
det |
All,patients |
R3395 |
T3913 |
T3914 |
nsubj |
patients,gave |
R3396 |
T3914 |
T3914 |
ROOT |
gave,gave |
R3397 |
T3915 |
T3916 |
amod |
informed,consent |
R3398 |
T3916 |
T3914 |
dobj |
consent,gave |
R3399 |
T3917 |
T3916 |
cc |
and,consent |
R3400 |
T3918 |
T3919 |
det |
the,study |
R3401 |
T3919 |
T3921 |
nsubjpass |
study,approved |
R3402 |
T3920 |
T3921 |
auxpass |
was,approved |
R3403 |
T3921 |
T3914 |
conj |
approved,gave |
R3404 |
T3922 |
T3921 |
agent |
by,approved |
R3405 |
T3923 |
T3925 |
det |
the,Committee |
R3406 |
T3924 |
T3925 |
compound |
Ethics,Committee |
R3407 |
T3925 |
T3922 |
pobj |
Committee,by |
R3408 |
T3926 |
T3925 |
prep |
of,Committee |
R3409 |
T3927 |
T3929 |
det |
the,Brompton |
R3410 |
T3928 |
T3929 |
compound |
Royal,Brompton |
R3411 |
T3929 |
T3926 |
pobj |
Brompton,of |
R3412 |
T3930 |
T3929 |
cc |
and,Brompton |
R3413 |
T3931 |
T3934 |
compound |
Harefield,Trust |
R3414 |
T3932 |
T3934 |
compound |
Hospitals,Trust |
R3415 |
T3933 |
T3934 |
compound |
NHS,Trust |
R3416 |
T3934 |
T3929 |
conj |
Trust,Brompton |
R3417 |
T3935 |
T3921 |
punct |
.,approved |
R3418 |
T3936 |
T3938 |
det |
The,study |
R3419 |
T3937 |
T3938 |
amod |
clinical,study |
R3420 |
T3938 |
T3940 |
nsubjpass |
study,conducted |
R3421 |
T3939 |
T3940 |
auxpass |
was,conducted |
R3422 |
T3940 |
T3940 |
ROOT |
conducted,conducted |
R3423 |
T3941 |
T3940 |
prep |
before,conducted |
R3424 |
T3942 |
T3943 |
det |
the,requirement |
R3425 |
T3943 |
T3941 |
pobj |
requirement,before |
R3426 |
T3944 |
T3943 |
prep |
for,requirement |
R3427 |
T3945 |
T3947 |
compound |
Clinical,Registration |
R3428 |
T3946 |
T3947 |
compound |
Trial,Registration |
R3429 |
T3947 |
T3944 |
pobj |
Registration,for |
R3430 |
T3948 |
T3940 |
punct |
.,conducted |
R3577 |
T4142 |
T4142 |
ROOT |
Antibodies,Antibodies |
R3578 |
T4143 |
T4142 |
cc |
and,Antibodies |
R3579 |
T4144 |
T4142 |
conj |
Reagents,Antibodies |
R3580 |
T4145 |
T4147 |
det |
The,antibodies |
R3581 |
T4146 |
T4147 |
amod |
monoclonal,antibodies |
R3582 |
T4147 |
T4159 |
nsubjpass |
antibodies,purchased |
R3583 |
T4148 |
T4147 |
prep |
against,antibodies |
R3584 |
T4149 |
T4150 |
compound |
human,CD3 |
R3585 |
T4150 |
T4148 |
pobj |
CD3,against |
R3586 |
T4151 |
T4150 |
punct |
",",CD3 |
R3587 |
T4152 |
T4150 |
conj |
CD28,CD3 |
R3588 |
T4153 |
T4152 |
punct |
",",CD28 |
R3589 |
T4154 |
T4152 |
conj |
GR,CD28 |
R3590 |
T4155 |
T4154 |
punct |
",",GR |
R3591 |
T4156 |
T4154 |
cc |
and,GR |
R3592 |
T4157 |
T4154 |
conj |
importin-α,GR |
R3593 |
T4158 |
T4159 |
auxpass |
were,purchased |
R3594 |
T4159 |
T4159 |
ROOT |
purchased,purchased |
R3595 |
T4160 |
T4159 |
prep |
from,purchased |
R3596 |
T4161 |
T4162 |
compound |
BD,Biosciences |
R3597 |
T4162 |
T4160 |
pobj |
Biosciences,from |
R3598 |
T4163 |
T4162 |
punct |
(,Biosciences |
R3599 |
T4164 |
T4162 |
npadvmod |
Oxford,Biosciences |
R3600 |
T4165 |
T4164 |
punct |
",",Oxford |
R3601 |
T4166 |
T4167 |
compound |
United,Kingdom |
R3602 |
T4167 |
T4164 |
appos |
Kingdom,Oxford |
R3603 |
T4168 |
T4164 |
punct |
),Oxford |
R3604 |
T4169 |
T4159 |
punct |
.,purchased |
R3605 |
T4170 |
T4171 |
compound |
Rabbit,antibodies |
R3606 |
T4171 |
T4186 |
nsubjpass |
antibodies,obtained |
R3607 |
T4172 |
T4171 |
prep |
against,antibodies |
R3608 |
T4173 |
T4174 |
compound |
human,GATA-3 |
R3609 |
T4174 |
T4172 |
pobj |
GATA-3,against |
R3610 |
T4175 |
T4174 |
punct |
(,GATA-3 |
R3611 |
T4176 |
T4174 |
appos |
H-48,GATA-3 |
R3612 |
T4177 |
T4174 |
punct |
),GATA-3 |
R3613 |
T4178 |
T4174 |
cc |
and,GATA-3 |
R3614 |
T4179 |
T4174 |
conj |
GR,GATA-3 |
R3615 |
T4180 |
T4181 |
punct |
(,E-20 |
R3616 |
T4181 |
T4174 |
conj |
E-20,GATA-3 |
R3617 |
T4182 |
T4181 |
punct |
",",E-20 |
R3618 |
T4183 |
T4181 |
amod |
sc-1003,E-20 |
R3619 |
T4184 |
T4181 |
punct |
),E-20 |
R3620 |
T4185 |
T4186 |
auxpass |
were,obtained |
R3621 |
T4186 |
T4186 |
ROOT |
obtained,obtained |
R3622 |
T4187 |
T4186 |
prep |
from,obtained |
R3623 |
T4188 |
T4190 |
compound |
Santa,Biotechnology |
R3624 |
T4189 |
T4190 |
compound |
Cruz,Biotechnology |
R3625 |
T4190 |
T4187 |
pobj |
Biotechnology,from |
R3626 |
T4191 |
T4190 |
punct |
(,Biotechnology |
R3627 |
T4192 |
T4193 |
compound |
Santa,Cruz |
R3628 |
T4193 |
T4190 |
appos |
Cruz,Biotechnology |
R3629 |
T4194 |
T4193 |
punct |
",",Cruz |
R3630 |
T4195 |
T4193 |
conj |
California,Cruz |
R3631 |
T4196 |
T4195 |
punct |
",",California |
R3632 |
T4197 |
T4198 |
compound |
United,States |
R3633 |
T4198 |
T4195 |
appos |
States,California |
R3634 |
T4199 |
T4195 |
punct |
),California |
R3635 |
T4200 |
T4190 |
punct |
",",Biotechnology |
R3636 |
T4201 |
T4203 |
amod |
polyclonal,antibodies |
R3637 |
T4202 |
T4203 |
compound |
rabbit,antibodies |
R3638 |
T4203 |
T4186 |
dobj |
antibodies,obtained |
R3639 |
T4204 |
T4186 |
prep |
against,obtained |
R3640 |
T4205 |
T4207 |
amod |
phospho-p38,kinase |
R3641 |
T4206 |
T4207 |
compound |
MAP,kinase |
R3642 |
T4207 |
T4204 |
pobj |
kinase,against |
R3643 |
T4208 |
T4207 |
cc |
and,kinase |
R3644 |
T4209 |
T4207 |
conj |
phospho-ATF-2,kinase |
R3645 |
T4210 |
T4207 |
prep |
from,kinase |
R3646 |
T4211 |
T4212 |
compound |
Cell,Signaling |
R3647 |
T4212 |
T4210 |
pobj |
Signaling,from |
R3648 |
T4213 |
T4225 |
nmod |
Technology,antibody |
R3649 |
T4214 |
T4217 |
punct |
(,Biolabs |
R3650 |
T4215 |
T4217 |
compound |
New,Biolabs |
R3651 |
T4216 |
T4217 |
compound |
England,Biolabs |
R3652 |
T4217 |
T4213 |
appos |
Biolabs,Technology |
R3653 |
T4218 |
T4217 |
punct |
",",Biolabs |
R3654 |
T4219 |
T4217 |
conj |
Hertford,Biolabs |
R3655 |
T4220 |
T4219 |
punct |
",",Hertford |
R3656 |
T4221 |
T4219 |
conj |
UK,Hertford |
R3657 |
T4222 |
T4217 |
punct |
),Biolabs |
R3658 |
T4223 |
T4217 |
punct |
",",Biolabs |
R3659 |
T4224 |
T4225 |
amod |
monoclonal,antibody |
R3660 |
T4225 |
T4243 |
nsubj |
antibody,antibodies |
R3661 |
T4226 |
T4225 |
prep |
against,antibody |
R3662 |
T4227 |
T4226 |
pobj |
phosphoserine,against |
R3663 |
T4228 |
T4230 |
punct |
(,4H4 |
R3664 |
T4229 |
T4230 |
compound |
clone,4H4 |
R3665 |
T4230 |
T4227 |
appos |
4H4,phosphoserine |
R3666 |
T4231 |
T4230 |
punct |
),4H4 |
R3667 |
T4232 |
T4230 |
prep |
from,4H4 |
R3668 |
T4233 |
T4235 |
compound |
Affiniti,Products |
R3669 |
T4234 |
T4235 |
compound |
Research,Products |
R3670 |
T4235 |
T4232 |
pobj |
Products,from |
R3671 |
T4236 |
T4235 |
punct |
(,Products |
R3672 |
T4237 |
T4235 |
npadvmod |
Exeter,Products |
R3673 |
T4238 |
T4237 |
punct |
",",Exeter |
R3674 |
T4239 |
T4237 |
appos |
UK,Exeter |
R3675 |
T4240 |
T4237 |
punct |
),Exeter |
R3676 |
T4241 |
T4235 |
punct |
",",Products |
R3677 |
T4242 |
T4227 |
cc |
and,phosphoserine |
R3678 |
T4243 |
T4212 |
dobj |
antibodies,Signaling |
R3679 |
T4244 |
T4243 |
prep |
against,antibodies |
R3680 |
T4245 |
T4247 |
compound |
rabbit,TRITC |
R3681 |
T4246 |
T4247 |
compound |
IgG-conjugated,TRITC |
R3682 |
T4247 |
T4244 |
pobj |
TRITC,against |
R3683 |
T4248 |
T4247 |
prep |
from,TRITC |
R3684 |
T4249 |
T4250 |
compound |
Dako,Cytomation |
R3685 |
T4250 |
T4248 |
pobj |
Cytomation,from |
R3686 |
T4251 |
T4250 |
punct |
(,Cytomation |
R3687 |
T4252 |
T4250 |
appos |
Cambridge,Cytomation |
R3688 |
T4253 |
T4252 |
punct |
",",Cambridge |
R3689 |
T4254 |
T4252 |
appos |
UK,Cambridge |
R3690 |
T4255 |
T4252 |
punct |
),Cambridge |
R3691 |
T4256 |
T4186 |
punct |
.,obtained |
R3692 |
T4257 |
T4259 |
det |
The,antibody |
R3693 |
T4258 |
T4259 |
amod |
anti-GR,antibody |
R3694 |
T4259 |
T4274 |
nsubjpass |
antibody,used |
R3695 |
T4260 |
T4259 |
punct |
(,antibody |
R3696 |
T4261 |
T4259 |
appos |
Clone,antibody |
R3697 |
T4262 |
T4261 |
nummod |
41,Clone |
R3698 |
T4263 |
T4261 |
punct |
),Clone |
R3699 |
T4264 |
T4259 |
prep |
from,antibody |
R3700 |
T4265 |
T4267 |
compound |
BD,Laboratories |
R3701 |
T4266 |
T4267 |
compound |
Transduction,Laboratories |
R3702 |
T4267 |
T4264 |
pobj |
Laboratories,from |
R3703 |
T4268 |
T4267 |
punct |
(,Laboratories |
R3704 |
T4269 |
T4267 |
npadvmod |
Oxford,Laboratories |
R3705 |
T4270 |
T4269 |
punct |
",",Oxford |
R3706 |
T4271 |
T4269 |
appos |
UK,Oxford |
R3707 |
T4272 |
T4269 |
punct |
),Oxford |
R3708 |
T4273 |
T4274 |
auxpass |
was,used |
R3709 |
T4274 |
T4274 |
ROOT |
used,used |
R3710 |
T4275 |
T4274 |
prep |
for,used |
R3711 |
T4276 |
T4278 |
amod |
Western,analysis |
R3712 |
T4277 |
T4278 |
compound |
blot,analysis |
R3713 |
T4278 |
T4275 |
pobj |
analysis,for |
R3714 |
T4279 |
T4274 |
punct |
.,used |
R3715 |
T4280 |
T4282 |
det |
All,reagents |
R3716 |
T4281 |
T4282 |
amod |
other,reagents |
R3717 |
T4282 |
T4284 |
nsubjpass |
reagents,purchased |
R3718 |
T4283 |
T4284 |
auxpass |
were,purchased |
R3719 |
T4284 |
T4284 |
ROOT |
purchased,purchased |
R3720 |
T4285 |
T4284 |
prep |
from,purchased |
R3721 |
T4286 |
T4285 |
pobj |
Sigma,from |
R3722 |
T4287 |
T4288 |
punct |
(,Poole |
R3723 |
T4288 |
T4284 |
npadvmod |
Poole,purchased |
R3724 |
T4289 |
T4288 |
punct |
",",Poole |
R3725 |
T4290 |
T4288 |
appos |
UK,Poole |
R3726 |
T4291 |
T4288 |
punct |
),Poole |
R3727 |
T4292 |
T4284 |
punct |
.,purchased |
R374 |
T484 |
T488 |
nmod |
interleukin,-4 |
R375 |
T477 |
T476 |
prep |
in,role |
R376 |
T478 |
T477 |
pcomp |
regulating,in |
R377 |
T479 |
T480 |
det |
the,expression |
R378 |
T480 |
T478 |
dobj |
expression,regulating |
R379 |
T485 |
T484 |
punct |
(,interleukin |
R380 |
T481 |
T480 |
prep |
of,expression |
R381 |
T482 |
T483 |
det |
the,cytokines |
R382 |
T483 |
T481 |
pobj |
cytokines,of |
R383 |
T486 |
T484 |
appos |
IL,interleukin |
R384 |
T487 |
T484 |
punct |
),interleukin |
R3841 |
T4470 |
T4471 |
compound |
Cell,Culture |
R3842 |
T4471 |
T4474 |
nsubj |
Culture,Isolation |
R3843 |
T4472 |
T4471 |
cc |
and,Culture |
R3844 |
T4473 |
T4471 |
conj |
PBMC,Culture |
R3845 |
T4474 |
T4498 |
nsubjpass |
Isolation,cultured |
R3846 |
T4475 |
T4479 |
det |
A,line |
R3847 |
T4476 |
T4478 |
amod |
human,cell |
R3848 |
T4477 |
T4478 |
compound |
T,cell |
R3849 |
T4478 |
T4479 |
compound |
cell,line |
R385 |
T488 |
T473 |
npadvmod |
-4,plays |
R3850 |
T4479 |
T4474 |
dobj |
line,Isolation |
R3851 |
T4480 |
T4484 |
punct |
(,purchased |
R3852 |
T4481 |
T4484 |
nsubjpass |
HuT-78,purchased |
R3853 |
T4482 |
T4481 |
punct |
),HuT-78 |
R3854 |
T4483 |
T4484 |
auxpass |
was,purchased |
R3855 |
T4484 |
T4474 |
relcl |
purchased,Isolation |
R3856 |
T4485 |
T4484 |
prep |
from,purchased |
R3857 |
T4486 |
T4488 |
compound |
ECACC,Collection |
R3858 |
T4487 |
T4488 |
compound |
European,Collection |
R3859 |
T4488 |
T4485 |
pobj |
Collection,from |
R386 |
T489 |
T488 |
punct |
",",-4 |
R3860 |
T4489 |
T4488 |
prep |
of,Collection |
R3861 |
T4490 |
T4491 |
compound |
Cell,Culture |
R3862 |
T4491 |
T4489 |
pobj |
Culture,of |
R3863 |
T4492 |
T4488 |
punct |
(,Collection |
R3864 |
T4493 |
T4488 |
appos |
Wiltshire,Collection |
R3865 |
T4494 |
T4493 |
punct |
",",Wiltshire |
R3866 |
T4495 |
T4493 |
appos |
UK,Wiltshire |
R3867 |
T4496 |
T4493 |
punct |
),Wiltshire |
R3868 |
T4497 |
T4498 |
auxpass |
were,cultured |
R3869 |
T4498 |
T4498 |
ROOT |
cultured,cultured |
R387 |
T490 |
T488 |
conj |
IL-5,-4 |
R3870 |
T4499 |
T4501 |
mark |
as,described |
R3871 |
T4500 |
T4501 |
advmod |
previously,described |
R3872 |
T4501 |
T4498 |
advcl |
described,cultured |
R3873 |
T4502 |
T4504 |
nmod |
[,] |
R3874 |
T4503 |
T4504 |
nummod |
12,] |
R3875 |
T4504 |
T4501 |
dobj |
],described |
R3876 |
T4505 |
T4498 |
punct |
.,cultured |
R3877 |
T4506 |
T4508 |
nsubjpass |
PBMCs,isolated |
R3878 |
T4507 |
T4508 |
auxpass |
were,isolated |
R3879 |
T4508 |
T4529 |
ccomp |
isolated,described |
R388 |
T491 |
T490 |
punct |
",",IL-5 |
R3880 |
T4509 |
T4508 |
agent |
by,isolated |
R3881 |
T4510 |
T4511 |
compound |
density,centrifugation |
R3882 |
T4511 |
T4509 |
pobj |
centrifugation,by |
R3883 |
T4512 |
T4511 |
prep |
over,centrifugation |
R3884 |
T4513 |
T4512 |
pobj |
Ficoll-Hypaque,over |
R3885 |
T4514 |
T4515 |
punct |
(,density |
R3886 |
T4515 |
T4513 |
appos |
density,Ficoll-Hypaque |
R3887 |
T4516 |
T4515 |
punct |
",",density |
R3888 |
T4517 |
T4518 |
nummod |
1.077,g/ml |
R3889 |
T4518 |
T4515 |
appos |
g/ml,density |
R389 |
T492 |
T490 |
cc |
and,IL-5 |
R3890 |
T4519 |
T4529 |
punct |
;,described |
R3891 |
T4520 |
T4521 |
compound |
Amersham,Biosciences |
R3892 |
T4521 |
T4529 |
nsubj |
Biosciences,described |
R3893 |
T4522 |
T4521 |
punct |
",",Biosciences |
R3894 |
T4523 |
T4521 |
conj |
Amersham,Biosciences |
R3895 |
T4524 |
T4523 |
punct |
",",Amersham |
R3896 |
T4525 |
T4523 |
conj |
UK,Amersham |
R3897 |
T4526 |
T4521 |
punct |
),Biosciences |
R3898 |
T4527 |
T4529 |
mark |
as,described |
R3899 |
T4528 |
T4529 |
advmod |
previously,described |
R390 |
T493 |
T490 |
conj |
IL-13,IL-5 |
R3900 |
T4529 |
T4529 |
ROOT |
described,described |
R3901 |
T4530 |
T4532 |
nmod |
[,] |
R3902 |
T4531 |
T4532 |
nummod |
34,] |
R3903 |
T4532 |
T4529 |
dobj |
],described |
R3904 |
T4533 |
T4529 |
punct |
.,described |
R3905 |
T4534 |
T4536 |
nsubjpass |
Cells,stimulated |
R3906 |
T4535 |
T4536 |
auxpass |
were,stimulated |
R3907 |
T4536 |
T4536 |
ROOT |
stimulated,stimulated |
R3908 |
T4537 |
T4536 |
prep |
with,stimulated |
R3909 |
T4538 |
T4540 |
amod |
anti-CD3,CD28 |
R391 |
T494 |
T490 |
prep |
from,IL-5 |
R3910 |
T4539 |
T4540 |
compound |
/,CD28 |
R3911 |
T4540 |
T4537 |
pobj |
CD28,with |
R3912 |
T4541 |
T4540 |
punct |
(,CD28 |
R3913 |
T4542 |
T4543 |
nummod |
1,µg |
R3914 |
T4543 |
T4545 |
nmod |
µg,ml |
R3915 |
T4544 |
T4545 |
compound |
/,ml |
R3916 |
T4545 |
T4540 |
appos |
ml,CD28 |
R3917 |
T4546 |
T4545 |
npadvmod |
each,ml |
R3918 |
T4547 |
T4540 |
punct |
),CD28 |
R3919 |
T4548 |
T4536 |
prep |
for,stimulated |
R392 |
T495 |
T496 |
compound |
T,helper-2 |
R3920 |
T4549 |
T4550 |
nummod |
1,h |
R3921 |
T4550 |
T4548 |
pobj |
h,for |
R3922 |
T4551 |
T4550 |
prep |
at,h |
R3923 |
T4552 |
T4553 |
nummod |
37,° |
R3924 |
T4553 |
T4551 |
pobj |
°,at |
R3925 |
T4554 |
T4550 |
npadvmod |
C,h |
R3926 |
T4555 |
T4556 |
aux |
to,stimulate |
R3927 |
T4556 |
T4536 |
advcl |
stimulate,stimulated |
R3928 |
T4557 |
T4559 |
amod |
Th2,release |
R3929 |
T4558 |
T4559 |
compound |
cytokine,release |
R393 |
T496 |
T494 |
pobj |
helper-2,from |
R3930 |
T4559 |
T4556 |
dobj |
release,stimulate |
R3931 |
T4560 |
T4559 |
prep |
in,release |
R3932 |
T4561 |
T4562 |
det |
the,presence |
R3933 |
T4562 |
T4560 |
pobj |
presence,in |
R3934 |
T4563 |
T4562 |
cc |
or,presence |
R3935 |
T4564 |
T4562 |
conj |
absence,presence |
R3936 |
T4565 |
T4562 |
prep |
of,presence |
R3937 |
T4566 |
T4565 |
pobj |
FP,of |
R3938 |
T4567 |
T4569 |
punct |
(,− |
R3939 |
T4568 |
T4569 |
nummod |
10,− |
R394 |
T497 |
T496 |
punct |
(,helper-2 |
R3940 |
T4569 |
T4566 |
appos |
−,FP |
R3941 |
T4570 |
T4572 |
quantmod |
12,10 |
R3942 |
T4571 |
T4572 |
quantmod |
to,10 |
R3943 |
T4572 |
T4574 |
nummod |
10,8M |
R3944 |
T4573 |
T4574 |
nummod |
−,8M |
R3945 |
T4574 |
T4569 |
npadvmod |
8M,− |
R3946 |
T4575 |
T4569 |
punct |
),− |
R3947 |
T4576 |
T4536 |
punct |
.,stimulated |
R3948 |
T4577 |
T4579 |
nsubjpass |
Cytospins,prepared |
R3949 |
T4578 |
T4579 |
auxpass |
were,prepared |
R395 |
T498 |
T496 |
appos |
Th2,helper-2 |
R3950 |
T4579 |
T4582 |
amod |
prepared,localization |
R3951 |
T4580 |
T4579 |
cc |
and,prepared |
R3952 |
T4581 |
T4579 |
conj |
GATA-3,prepared |
R3953 |
T4582 |
T4582 |
ROOT |
localization,localization |
R3954 |
T4583 |
T4582 |
acl |
determined,localization |
R3955 |
T4584 |
T4583 |
agent |
by,determined |
R3956 |
T4585 |
T4586 |
amod |
confocal,microscopy |
R3957 |
T4586 |
T4584 |
pobj |
microscopy,by |
R3958 |
T4587 |
T4589 |
mark |
as,described |
R3959 |
T4588 |
T4589 |
advmod |
previously,described |
R396 |
T499 |
T496 |
punct |
),helper-2 |
R3960 |
T4589 |
T4582 |
advcl |
described,localization |
R3961 |
T4590 |
T4592 |
nmod |
[,] |
R3962 |
T4591 |
T4592 |
nummod |
12,] |
R3963 |
T4592 |
T4589 |
dobj |
],described |
R3964 |
T4593 |
T4582 |
punct |
.,localization |
R397 |
T500 |
T494 |
pobj |
cells,from |
R398 |
T590 |
T589 |
amod |
independent,mechanism |
R399 |
T501 |
T473 |
cc |
and,plays |
R400 |
T591 |
T590 |
prep |
of,independent |
R401 |
T592 |
T593 |
amod |
nuclear,factor-κB |
R402 |
T502 |
T503 |
advmod |
therefore,is |
R403 |
T593 |
T591 |
pobj |
factor-κB,of |
R404 |
T594 |
T577 |
cc |
and,inhibits |
R405 |
T595 |
T577 |
conj |
is,inhibits |
R406 |
T503 |
T473 |
conj |
is,plays |
R4061 |
T4717 |
T4721 |
amod |
Reverse,RNA |
R4062 |
T4718 |
T4721 |
compound |
Transcription,RNA |
R4063 |
T4719 |
T4721 |
compound |
PCR,RNA |
R4064 |
T4720 |
T4721 |
compound |
Total,RNA |
R4065 |
T4721 |
T4723 |
nsubjpass |
RNA,extracted |
R4066 |
T4722 |
T4723 |
auxpass |
was,extracted |
R4067 |
T4723 |
T4723 |
ROOT |
extracted,extracted |
R4068 |
T4724 |
T4723 |
advcl |
using,extracted |
R4069 |
T4725 |
T4726 |
compound |
lysis,buffer |
R407 |
T504 |
T506 |
det |
a,mediator |
R4070 |
T4726 |
T4724 |
dobj |
buffer,using |
R4071 |
T4727 |
T4726 |
punct |
(,buffer |
R4072 |
T4728 |
T4729 |
compound |
RNeasy,kit |
R4073 |
T4729 |
T4726 |
appos |
kit,buffer |
R4074 |
T4730 |
T4726 |
punct |
;,buffer |
R4075 |
T4731 |
T4726 |
conj |
Qiagen,buffer |
R4076 |
T4732 |
T4731 |
punct |
",",Qiagen |
R4077 |
T4733 |
T4731 |
conj |
Crawley,Qiagen |
R4078 |
T4734 |
T4733 |
punct |
",",Crawley |
R4079 |
T4735 |
T4733 |
conj |
UK,Crawley |
R408 |
T505 |
T506 |
amod |
key,mediator |
R4080 |
T4736 |
T4731 |
punct |
),Qiagen |
R4081 |
T4737 |
T4723 |
punct |
.,extracted |
R4082 |
T4738 |
T4745 |
prep |
During,digested |
R4083 |
T4739 |
T4740 |
compound |
RNA,purification |
R4084 |
T4740 |
T4738 |
pobj |
purification,During |
R4085 |
T4741 |
T4745 |
punct |
",",digested |
R4086 |
T4742 |
T4743 |
amod |
genomic,DNA |
R4087 |
T4743 |
T4745 |
nsubjpass |
DNA,digested |
R4088 |
T4744 |
T4745 |
auxpass |
was,digested |
R4089 |
T4745 |
T4745 |
ROOT |
digested,digested |
R409 |
T506 |
T503 |
attr |
mediator,is |
R4090 |
T4746 |
T4745 |
prep |
with,digested |
R4091 |
T4747 |
T4748 |
compound |
RNase-free,DNase |
R4092 |
T4748 |
T4746 |
pobj |
DNase,with |
R4093 |
T4749 |
T4751 |
punct |
(,Biosciences |
R4094 |
T4750 |
T4751 |
compound |
Amersham,Biosciences |
R4095 |
T4751 |
T4748 |
appos |
Biosciences,DNase |
R4096 |
T4752 |
T4751 |
punct |
),Biosciences |
R4097 |
T4753 |
T4745 |
punct |
.,digested |
R4098 |
T4754 |
T4757 |
advmod |
Next,µg |
R4099 |
T4755 |
T4757 |
punct |
",",µg |
R410 |
T507 |
T506 |
prep |
of,mediator |
R4100 |
T4756 |
T4757 |
nummod |
0.5,µg |
R4101 |
T4757 |
T4763 |
nsubjpass |
µg,transcribed |
R4102 |
T4758 |
T4757 |
prep |
of,µg |
R4103 |
T4759 |
T4760 |
amod |
total,RNA |
R4104 |
T4760 |
T4758 |
pobj |
RNA,of |
R4105 |
T4761 |
T4763 |
auxpass |
was,transcribed |
R4106 |
T4762 |
T4763 |
advmod |
reversed,transcribed |
R4107 |
T4763 |
T4763 |
ROOT |
transcribed,transcribed |
R4108 |
T4764 |
T4763 |
advcl |
using,transcribed |
R4109 |
T4765 |
T4768 |
det |
the,virus |
R411 |
T508 |
T509 |
amod |
allergic,diseases |
R4110 |
T4766 |
T4767 |
amod |
avian,myeloblastosis |
R4111 |
T4767 |
T4768 |
compound |
myeloblastosis,virus |
R4112 |
T4768 |
T4764 |
dobj |
virus,using |
R4113 |
T4769 |
T4771 |
nmod |
RT,Promega |
R4114 |
T4770 |
T4771 |
punct |
(,Promega |
R4115 |
T4771 |
T4768 |
appos |
Promega,virus |
R4116 |
T4772 |
T4771 |
punct |
",",Promega |
R4117 |
T4773 |
T4771 |
conj |
Southampton,Promega |
R4118 |
T4774 |
T4773 |
punct |
",",Southampton |
R4119 |
T4775 |
T4773 |
conj |
UK,Southampton |
R412 |
T509 |
T507 |
pobj |
diseases,of |
R4120 |
T4776 |
T4771 |
punct |
),Promega |
R4121 |
T4777 |
T4763 |
punct |
.,transcribed |
R4122 |
T4778 |
T4784 |
prep |
For,carried |
R4123 |
T4779 |
T4780 |
amod |
relative,quantification |
R4124 |
T4780 |
T4778 |
pobj |
quantification,For |
R4125 |
T4781 |
T4784 |
punct |
",",carried |
R4126 |
T4782 |
T4784 |
nsubjpass |
RT-PCR,carried |
R4127 |
T4783 |
T4784 |
auxpass |
was,carried |
R4128 |
T4784 |
T4784 |
ROOT |
carried,carried |
R4129 |
T4785 |
T4784 |
prt |
out,carried |
R413 |
T510 |
T473 |
punct |
.,plays |
R4130 |
T4786 |
T4784 |
advcl |
using,carried |
R4131 |
T4787 |
T4788 |
compound |
cDNA,probes |
R4132 |
T4788 |
T4786 |
dobj |
probes,using |
R4133 |
T4789 |
T4784 |
punct |
.,carried |
R4134 |
T4790 |
T4793 |
nsubj |
Primers,were |
R4135 |
T4791 |
T4790 |
prep |
for,Primers |
R4136 |
T4792 |
T4791 |
pobj |
IL-4,for |
R4137 |
T4793 |
T4793 |
ROOT |
were,were |
R4138 |
T4794 |
T4793 |
prep |
from,were |
R4139 |
T4795 |
T4794 |
pobj |
Sigma-Genosys,from |
R414 |
T596 |
T595 |
acomp |
due,is |
R4140 |
T4796 |
T4795 |
punct |
(,Sigma-Genosys |
R4141 |
T4797 |
T4795 |
appos |
Cambridge,Sigma-Genosys |
R4142 |
T4798 |
T4797 |
punct |
",",Cambridge |
R4143 |
T4799 |
T4797 |
appos |
UK,Cambridge |
R4144 |
T4800 |
T4797 |
punct |
),Cambridge |
R4145 |
T4801 |
T4793 |
punct |
.,were |
R4146 |
T4802 |
T4806 |
nsubj |
Sequences,are |
R4147 |
T4803 |
T4802 |
prep |
of,Sequences |
R4148 |
T4804 |
T4803 |
pobj |
GADPH,of |
R4149 |
T4805 |
T4802 |
acl |
used,Sequences |
R415 |
T597 |
T595 |
punct |
",",is |
R4150 |
T4806 |
T4806 |
ROOT |
are,are |
R4151 |
T4807 |
T4808 |
mark |
as,follows |
R4152 |
T4808 |
T4806 |
advcl |
follows,are |
R4153 |
T4809 |
T4806 |
punct |
:,are |
R4154 |
T4810 |
T4816 |
advmod |
forward,reverse |
R4155 |
T4811 |
T4814 |
nummod |
5,CCACCCATGGCAAATTCCATGGC |
R4156 |
T4812 |
T4814 |
punct |
′,CCACCCATGGCAAATTCCATGGC |
R4157 |
T4813 |
T4814 |
punct |
-,CCACCCATGGCAAATTCCATGGC |
R4158 |
T4814 |
T4816 |
npadvmod |
CCACCCATGGCAAATTCCATGGC,reverse |
R4159 |
T4815 |
T4816 |
punct |
",",reverse |
R416 |
T598 |
T595 |
prep |
in,is |
R4160 |
T4816 |
T4820 |
dep |
reverse,TCTAGACGGCAGGTCAGGTCCAC |
R4161 |
T4817 |
T4816 |
dobj |
3,reverse |
R4162 |
T4818 |
T4820 |
punct |
′,TCTAGACGGCAGGTCAGGTCCAC |
R4163 |
T4819 |
T4820 |
punct |
-,TCTAGACGGCAGGTCAGGTCCAC |
R4164 |
T4820 |
T4820 |
ROOT |
TCTAGACGGCAGGTCAGGTCCAC,TCTAGACGGCAGGTCAGGTCCAC |
R4165 |
T4821 |
T4820 |
punct |
.,TCTAGACGGCAGGTCAGGTCCAC |
R417 |
T511 |
T512 |
nsubj |
Corticosteroids,are |
R418 |
T599 |
T598 |
pobj |
part,in |
R419 |
T600 |
T595 |
punct |
",",is |
R420 |
T512 |
T512 |
ROOT |
are,are |
R421 |
T601 |
T577 |
prep |
to,inhibits |
R422 |
T602 |
T601 |
pobj |
competition,to |
R423 |
T603 |
T602 |
prep |
between,competition |
R424 |
T513 |
T514 |
advmod |
highly,effective |
R425 |
T604 |
T603 |
pobj |
GATA-3,between |
R426 |
T605 |
T604 |
cc |
and,GATA-3 |
R427 |
T514 |
T512 |
acomp |
effective,are |
R428 |
T606 |
T609 |
det |
the,receptor |
R429 |
T607 |
T609 |
amod |
ligand-activated,receptor |
R430 |
T608 |
T609 |
compound |
glucocorticoid,receptor |
R431 |
T515 |
T514 |
prep |
in,effective |
R432 |
T609 |
T604 |
conj |
receptor,GATA-3 |
R4322 |
T5013 |
T5014 |
compound |
Cell,Fractionation |
R4323 |
T5014 |
T5027 |
nsubjpass |
Fractionation,prepared |
R4324 |
T5015 |
T5014 |
punct |
",",Fractionation |
R4325 |
T5016 |
T5014 |
conj |
Immunoprecipitation,Fractionation |
R4326 |
T5017 |
T5016 |
punct |
",",Immunoprecipitation |
R4327 |
T5018 |
T5016 |
cc |
and,Immunoprecipitation |
R4328 |
T5019 |
T5022 |
amod |
Western,Nuclear |
R4329 |
T5020 |
T5022 |
compound |
Blot,Nuclear |
R433 |
T610 |
T609 |
prep |
for,receptor |
R4330 |
T5021 |
T5022 |
compound |
Analysis,Nuclear |
R4331 |
T5022 |
T5016 |
conj |
Nuclear,Immunoprecipitation |
R4332 |
T5023 |
T5022 |
cc |
and,Nuclear |
R4333 |
T5024 |
T5022 |
conj |
cytoplasmic,Nuclear |
R4334 |
T5025 |
T5014 |
appos |
fractions,Fractionation |
R4335 |
T5026 |
T5027 |
auxpass |
were,prepared |
R4336 |
T5027 |
T5027 |
ROOT |
prepared,prepared |
R4337 |
T5028 |
T5030 |
mark |
as,described |
R4338 |
T5029 |
T5030 |
advmod |
previously,described |
R4339 |
T5030 |
T5027 |
advcl |
described,prepared |
R434 |
T611 |
T612 |
amod |
nuclear,transport |
R4340 |
T5031 |
T5033 |
nmod |
[,] |
R4341 |
T5032 |
T5033 |
nummod |
35,] |
R4342 |
T5033 |
T5030 |
dobj |
],described |
R4343 |
T5034 |
T5027 |
punct |
.,prepared |
R4344 |
T5035 |
T5037 |
amod |
Whole,lysates |
R4345 |
T5036 |
T5037 |
compound |
cell,lysates |
R4346 |
T5037 |
T5039 |
nsubjpass |
lysates,prepared |
R4347 |
T5038 |
T5039 |
auxpass |
were,prepared |
R4348 |
T5039 |
T5039 |
ROOT |
prepared,prepared |
R4349 |
T5040 |
T5039 |
prep |
in,prepared |
R435 |
T612 |
T610 |
pobj |
transport,for |
R4350 |
T5041 |
T5043 |
compound |
NP-40,buffer |
R4351 |
T5042 |
T5043 |
compound |
lysis,buffer |
R4352 |
T5043 |
T5040 |
pobj |
buffer,in |
R4353 |
T5044 |
T5048 |
punct |
(,P-40 |
R4354 |
T5045 |
T5046 |
nummod |
0.5,% |
R4355 |
T5046 |
T5048 |
compound |
%,P-40 |
R4356 |
T5047 |
T5048 |
compound |
Nonidet,P-40 |
R4357 |
T5048 |
T5043 |
appos |
P-40,buffer |
R4358 |
T5049 |
T5048 |
punct |
",",P-40 |
R4359 |
T5050 |
T5054 |
nummod |
20,pH |
R436 |
T516 |
T515 |
pcomp |
suppressing,in |
R4360 |
T5051 |
T5054 |
compound |
mM,pH |
R4361 |
T5052 |
T5054 |
compound |
Tris-HCl,pH |
R4362 |
T5053 |
T5054 |
compound |
[,pH |
R4363 |
T5054 |
T5048 |
appos |
pH,P-40 |
R4364 |
T5055 |
T5056 |
nummod |
7.5,] |
R4365 |
T5056 |
T5056 |
ROOT |
],] |
R4366 |
T5057 |
T5056 |
punct |
",",] |
R4367 |
T5058 |
T5060 |
nummod |
150,NaCl |
R4368 |
T5059 |
T5060 |
compound |
mM,NaCl |
R4369 |
T5060 |
T5056 |
appos |
NaCl,] |
R437 |
T613 |
T610 |
prep |
through,for |
R4370 |
T5061 |
T5056 |
punct |
),] |
R4371 |
T5062 |
T5056 |
prep |
in,] |
R4372 |
T5063 |
T5064 |
det |
the,presence |
R4373 |
T5064 |
T5062 |
pobj |
presence,in |
R4374 |
T5065 |
T5064 |
prep |
of,presence |
R4375 |
T5066 |
T5069 |
amod |
complete,inhibitor |
R4376 |
T5067 |
T5069 |
compound |
protease,inhibitor |
R4377 |
T5068 |
T5069 |
compound |
cocktail,inhibitor |
R4378 |
T5069 |
T5065 |
pobj |
inhibitor,of |
R4379 |
T5070 |
T5039 |
punct |
.,prepared |
R438 |
T614 |
T616 |
det |
the,importer |
R4380 |
T5071 |
T5073 |
nsubjpass |
Lysates,centrifuged |
R4381 |
T5072 |
T5073 |
auxpass |
were,centrifuged |
R4382 |
T5073 |
T5073 |
ROOT |
centrifuged,centrifuged |
R4383 |
T5074 |
T5073 |
prep |
at,centrifuged |
R4384 |
T5075 |
T5076 |
nummod |
4,° |
R4385 |
T5076 |
T5074 |
pobj |
°,at |
R4386 |
T5077 |
T5073 |
conj |
C,centrifuged |
R4387 |
T5078 |
T5077 |
prep |
for,C |
R4388 |
T5079 |
T5080 |
nummod |
10,min |
R4389 |
T5080 |
T5078 |
pobj |
min,for |
R439 |
T615 |
T616 |
amod |
nuclear,importer |
R4390 |
T5081 |
T5080 |
prep |
at,min |
R4391 |
T5082 |
T5083 |
nummod |
"12,000",rpm |
R4392 |
T5083 |
T5081 |
pobj |
rpm,at |
R4393 |
T5084 |
T5073 |
prep |
in,centrifuged |
R4394 |
T5085 |
T5087 |
det |
an,microcentrifuge |
R4395 |
T5086 |
T5087 |
compound |
Eppendorf,microcentrifuge |
R4396 |
T5087 |
T5084 |
pobj |
microcentrifuge,in |
R4397 |
T5088 |
T5089 |
aux |
to,remove |
R4398 |
T5089 |
T5073 |
advcl |
remove,centrifuged |
R4399 |
T5090 |
T5091 |
amod |
cellular,debris |
R440 |
T616 |
T613 |
pobj |
importer,through |
R4400 |
T5091 |
T5089 |
dobj |
debris,remove |
R4401 |
T5092 |
T5073 |
punct |
.,centrifuged |
R4402 |
T5093 |
T5096 |
nsubjpass |
Samples,immunoprecipitated |
R4403 |
T5094 |
T5096 |
auxpass |
were,immunoprecipitated |
R4404 |
T5095 |
T5096 |
advmod |
then,immunoprecipitated |
R4405 |
T5096 |
T5096 |
ROOT |
immunoprecipitated,immunoprecipitated |
R4406 |
T5097 |
T5096 |
prep |
with,immunoprecipitated |
R4407 |
T5098 |
T5100 |
preconj |
either,µl |
R4408 |
T5099 |
T5100 |
nummod |
10,µl |
R4409 |
T5100 |
T5107 |
nsubj |
µl,using |
R441 |
T617 |
T609 |
conj |
importin-α,receptor |
R4410 |
T5101 |
T5100 |
prep |
of,µl |
R4411 |
T5102 |
T5101 |
pobj |
antibody,of |
R4412 |
T5103 |
T5102 |
prep |
against,antibody |
R4413 |
T5104 |
T5103 |
pobj |
GATA-3,against |
R4414 |
T5105 |
T5104 |
cc |
or,GATA-3 |
R4415 |
T5106 |
T5104 |
conj |
importin-α,GATA-3 |
R4416 |
T5107 |
T5097 |
pcomp |
using,with |
R4417 |
T5108 |
T5110 |
nmod |
A/G,slurry |
R4418 |
T5109 |
T5110 |
amod |
agarose,slurry |
R4419 |
T5110 |
T5107 |
dobj |
slurry,using |
R442 |
T618 |
T574 |
punct |
.,demonstrated |
R4420 |
T5111 |
T5107 |
prep |
in,using |
R4421 |
T5112 |
T5113 |
det |
the,presence |
R4422 |
T5113 |
T5111 |
pobj |
presence,in |
R4423 |
T5114 |
T5113 |
prep |
of,presence |
R4424 |
T5115 |
T5116 |
amod |
protease,inhibitor |
R4425 |
T5116 |
T5114 |
pobj |
inhibitor,of |
R4426 |
T5117 |
T5107 |
advcl |
using,using |
R4427 |
T5118 |
T5119 |
det |
the,Catch |
R4428 |
T5119 |
T5117 |
dobj |
Catch,using |
R4429 |
T5120 |
T5119 |
cc |
and,Catch |
R443 |
T619 |
T623 |
prep |
In,induces |
R4430 |
T5121 |
T5119 |
conj |
Release,Catch |
R4431 |
T5122 |
T5119 |
conj |
methodology,Catch |
R4432 |
T5123 |
T5125 |
punct |
(,Biotechnology |
R4433 |
T5124 |
T5125 |
compound |
Upstate,Biotechnology |
R4434 |
T5125 |
T5119 |
conj |
Biotechnology,Catch |
R4435 |
T5126 |
T5125 |
punct |
",",Biotechnology |
R4436 |
T5127 |
T5128 |
compound |
Lake,Placid |
R4437 |
T5128 |
T5125 |
conj |
Placid,Biotechnology |
R4438 |
T5129 |
T5128 |
punct |
",",Placid |
R4439 |
T5130 |
T5131 |
compound |
New,York |
R444 |
T517 |
T518 |
amod |
allergic,inflammation |
R4440 |
T5131 |
T5128 |
conj |
York,Placid |
R4441 |
T5132 |
T5131 |
punct |
",",York |
R4442 |
T5133 |
T5131 |
conj |
USA,York |
R4443 |
T5134 |
T5125 |
punct |
),Biotechnology |
R4444 |
T5135 |
T5096 |
punct |
.,immunoprecipitated |
R4445 |
T5136 |
T5138 |
amod |
Western,analysis |
R4446 |
T5137 |
T5138 |
compound |
blot,analysis |
R4447 |
T5138 |
T5140 |
nsubjpass |
analysis,performed |
R4448 |
T5139 |
T5140 |
auxpass |
was,performed |
R4449 |
T5140 |
T5140 |
ROOT |
performed,performed |
R445 |
T620 |
T619 |
pobj |
addition,In |
R4450 |
T5141 |
T5140 |
advcl |
using,performed |
R4451 |
T5142 |
T5141 |
dobj |
anti-GATA-3,using |
R4452 |
T5143 |
T5142 |
punct |
",",anti-GATA-3 |
R4453 |
T5144 |
T5142 |
conj |
anti-importin-α,anti-GATA-3 |
R4454 |
T5145 |
T5144 |
punct |
",",anti-importin-α |
R4455 |
T5146 |
T5144 |
conj |
anti-GR,anti-importin-α |
R4456 |
T5147 |
T5146 |
punct |
",",anti-GR |
R4457 |
T5148 |
T5150 |
amod |
anti-p-p38,kinase |
R4458 |
T5149 |
T5150 |
compound |
MAP,kinase |
R4459 |
T5150 |
T5146 |
conj |
kinase,anti-GR |
R446 |
T621 |
T623 |
punct |
",",induces |
R4460 |
T5151 |
T5150 |
punct |
",",kinase |
R4461 |
T5152 |
T5150 |
conj |
anti-p-ATF-2,kinase |
R4462 |
T5153 |
T5152 |
punct |
",",anti-p-ATF-2 |
R4463 |
T5154 |
T5152 |
cc |
and,anti-p-ATF-2 |
R4464 |
T5155 |
T5152 |
conj |
anti-p-serine,anti-p-ATF-2 |
R4465 |
T5156 |
T5140 |
punct |
.,performed |
R4466 |
T5157 |
T5158 |
amod |
Immunoreactive,proteins |
R4467 |
T5158 |
T5160 |
nsubjpass |
proteins,detected |
R4468 |
T5159 |
T5160 |
auxpass |
were,detected |
R4469 |
T5160 |
T5160 |
ROOT |
detected,detected |
R447 |
T622 |
T623 |
nsubj |
fluticasone,induces |
R4470 |
T5161 |
T5160 |
advcl |
using,detected |
R4471 |
T5162 |
T5166 |
det |
an,kit |
R4472 |
T5163 |
T5166 |
amod |
enhanced,kit |
R4473 |
T5164 |
T5165 |
compound |
chemiluminescence,ECL |
R4474 |
T5165 |
T5166 |
compound |
ECL,kit |
R4475 |
T5166 |
T5161 |
dobj |
kit,using |
R4476 |
T5167 |
T5166 |
punct |
(,kit |
R4477 |
T5168 |
T5169 |
compound |
Amersham,Biosciences |
R4478 |
T5169 |
T5166 |
appos |
Biosciences,kit |
R4479 |
T5170 |
T5166 |
punct |
),kit |
R448 |
T518 |
T516 |
dobj |
inflammation,suppressing |
R4480 |
T5171 |
T5160 |
punct |
.,detected |
R449 |
T623 |
T623 |
ROOT |
induces,induces |
R450 |
T624 |
T625 |
det |
the,expression |
R451 |
T625 |
T623 |
dobj |
expression,induces |
R452 |
T519 |
T512 |
punct |
",",are |
R453 |
T626 |
T625 |
prep |
of,expression |
R454 |
T627 |
T629 |
amod |
mitogen-activated,kinase |
R455 |
T628 |
T629 |
compound |
protein,kinase |
R456 |
T520 |
T512 |
cc |
but,are |
R457 |
T629 |
T626 |
pobj |
kinase,of |
R458 |
T630 |
T631 |
punct |
(,MAPK |
R459 |
T631 |
T629 |
appos |
MAPK,kinase |
R4593 |
T5318 |
T5321 |
compound |
Chromatin,immunoprecipitation |
R4594 |
T5319 |
T5321 |
compound |
Immunoprecipitation,immunoprecipitation |
R4595 |
T5320 |
T5321 |
compound |
Chromatin,immunoprecipitation |
R4596 |
T5321 |
T5326 |
nsubjpass |
immunoprecipitation,performed |
R4597 |
T5322 |
T5323 |
punct |
(,IP |
R4598 |
T5323 |
T5321 |
appos |
IP,immunoprecipitation |
R4599 |
T5324 |
T5321 |
punct |
),immunoprecipitation |
R460 |
T632 |
T629 |
punct |
),kinase |
R4600 |
T5325 |
T5326 |
auxpass |
was,performed |
R4601 |
T5326 |
T5326 |
ROOT |
performed,performed |
R4602 |
T5327 |
T5329 |
mark |
as,described |
R4603 |
T5328 |
T5329 |
advmod |
previously,described |
R4604 |
T5329 |
T5326 |
advcl |
described,performed |
R4605 |
T5330 |
T5332 |
nmod |
[,] |
R4606 |
T5331 |
T5332 |
nummod |
12,] |
R4607 |
T5332 |
T5329 |
dobj |
],described |
R4608 |
T5333 |
T5329 |
prep |
in,described |
R4609 |
T5334 |
T5335 |
compound |
HuT-78,T-cells |
R461 |
T633 |
T625 |
appos |
phosphatase-1,expression |
R4610 |
T5335 |
T5333 |
pobj |
T-cells,in |
R4611 |
T5336 |
T5335 |
prep |
with,T-cells |
R4612 |
T5337 |
T5338 |
nummod |
2,µg |
R4613 |
T5338 |
T5336 |
pobj |
µg,with |
R4614 |
T5339 |
T5338 |
prep |
of,µg |
R4615 |
T5340 |
T5339 |
pobj |
anti-GATA-3,of |
R4616 |
T5341 |
T5344 |
punct |
(,Biotechnology |
R4617 |
T5342 |
T5344 |
compound |
Santa,Biotechnology |
R4618 |
T5343 |
T5344 |
compound |
Cruz,Biotechnology |
R4619 |
T5344 |
T5340 |
appos |
Biotechnology,anti-GATA-3 |
R462 |
T634 |
T633 |
punct |
(,phosphatase-1 |
R4620 |
T5345 |
T5344 |
punct |
),Biotechnology |
R4621 |
T5346 |
T5344 |
punct |
",",Biotechnology |
R4622 |
T5347 |
T5344 |
cc |
or,Biotechnology |
R4623 |
T5348 |
T5350 |
amod |
isotypic,G |
R4624 |
T5349 |
T5350 |
compound |
immunoglobulin,G |
R4625 |
T5350 |
T5344 |
conj |
G,Biotechnology |
R4626 |
T5351 |
T5338 |
prep |
as,µg |
R4627 |
T5352 |
T5354 |
det |
a,control |
R4628 |
T5353 |
T5354 |
amod |
non-specific,control |
R4629 |
T5354 |
T5351 |
pobj |
control,as |
R463 |
T521 |
T522 |
poss |
their,effects |
R4630 |
T5355 |
T5358 |
punct |
(,Biotechnology |
R4631 |
T5356 |
T5357 |
compound |
Santa,Cruz |
R4632 |
T5357 |
T5358 |
compound |
Cruz,Biotechnology |
R4633 |
T5358 |
T5354 |
appos |
Biotechnology,control |
R4634 |
T5359 |
T5354 |
punct |
),control |
R4635 |
T5360 |
T5329 |
advmod |
overnight,described |
R4636 |
T5361 |
T5329 |
prep |
at,described |
R4637 |
T5362 |
T5363 |
nummod |
4,° |
R4638 |
T5363 |
T5366 |
nummod |
°,sequences |
R4639 |
T5364 |
T5365 |
compound |
C.,Promoter |
R464 |
T635 |
T633 |
appos |
MKP-1,phosphatase-1 |
R4640 |
T5365 |
T5366 |
compound |
Promoter,sequences |
R4641 |
T5366 |
T5368 |
nsubjpass |
sequences,detected |
R4642 |
T5367 |
T5368 |
auxpass |
were,detected |
R4643 |
T5368 |
T5326 |
conj |
detected,performed |
R4644 |
T5369 |
T5368 |
prep |
with,detected |
R4645 |
T5370 |
T5371 |
compound |
PCR,primers |
R4646 |
T5371 |
T5369 |
pobj |
primers,with |
R4647 |
T5372 |
T5371 |
prep |
for,primers |
R4648 |
T5373 |
T5375 |
det |
the,promoter |
R4649 |
T5374 |
T5375 |
compound |
IL-5,promoter |
R465 |
T636 |
T633 |
punct |
),phosphatase-1 |
R4650 |
T5375 |
T5372 |
pobj |
promoter,for |
R4651 |
T5376 |
T5375 |
punct |
(,promoter |
R4652 |
T5377 |
T5388 |
advmod |
−,′ |
R4653 |
T5378 |
T5388 |
meta |
445,′ |
R4654 |
T5379 |
T5378 |
prep |
to,445 |
R4655 |
T5380 |
T5379 |
pobj |
+4,to |
R4656 |
T5381 |
T5378 |
punct |
),445 |
R4657 |
T5382 |
T5388 |
punct |
:,′ |
R4658 |
T5383 |
T5388 |
advmod |
forward,′ |
R4659 |
T5384 |
T5388 |
nummod |
5,′ |
R466 |
T637 |
T633 |
punct |
",",phosphatase-1 |
R4660 |
T5385 |
T5387 |
punct |
′,TTAATCTAGCCACAGTCATAG-3 |
R4661 |
T5386 |
T5387 |
punct |
-,TTAATCTAGCCACAGTCATAG-3 |
R4662 |
T5387 |
T5388 |
compound |
TTAATCTAGCCACAGTCATAG-3,′ |
R4663 |
T5388 |
T5375 |
appos |
′,promoter |
R4664 |
T5389 |
T5388 |
cc |
and,′ |
R4665 |
T5390 |
T5388 |
conj |
reverse,′ |
R4666 |
T5391 |
T5388 |
punct |
:,′ |
R4667 |
T5392 |
T5395 |
nummod |
5,TCATGGCTCTGAAACGTTCTG-3 |
R4668 |
T5393 |
T5395 |
punct |
′,TCATGGCTCTGAAACGTTCTG-3 |
R4669 |
T5394 |
T5395 |
punct |
-,TCATGGCTCTGAAACGTTCTG-3 |
R467 |
T522 |
T525 |
nsubj |
effects,are |
R4670 |
T5395 |
T5396 |
compound |
TCATGGCTCTGAAACGTTCTG-3,′ |
R4671 |
T5396 |
T5388 |
appos |
′,′ |
R4672 |
T5397 |
T5368 |
punct |
.,detected |
R4673 |
T5398 |
T5400 |
nsubjpass |
PCR,performed |
R4674 |
T5399 |
T5400 |
auxpass |
was,performed |
R4675 |
T5400 |
T5400 |
ROOT |
performed,performed |
R4676 |
T5401 |
T5400 |
advcl |
using,performed |
R4677 |
T5402 |
T5406 |
det |
a,cycler |
R4678 |
T5403 |
T5404 |
nmod |
Hybaid,Omnigene |
R4679 |
T5404 |
T5406 |
nmod |
Omnigene,cycler |
R468 |
T638 |
T640 |
det |
the,inhibitor |
R4680 |
T5405 |
T5406 |
amod |
thermal,cycler |
R4681 |
T5406 |
T5401 |
dobj |
cycler,using |
R4682 |
T5407 |
T5408 |
punct |
(,Hybaid |
R4683 |
T5408 |
T5406 |
appos |
Hybaid,cycler |
R4684 |
T5409 |
T5408 |
punct |
",",Hybaid |
R4685 |
T5410 |
T5408 |
npadvmod |
Ashford,Hybaid |
R4686 |
T5411 |
T5410 |
punct |
",",Ashford |
R4687 |
T5412 |
T5410 |
appos |
UK,Ashford |
R4688 |
T5413 |
T5408 |
punct |
),Hybaid |
R4689 |
T5414 |
T5408 |
prep |
with,Hybaid |
R469 |
T639 |
T640 |
amod |
endogenous,inhibitor |
R4690 |
T5415 |
T5416 |
compound |
cycling,parameters |
R4691 |
T5416 |
T5414 |
pobj |
parameters,with |
R4692 |
T5417 |
T5416 |
prep |
of,parameters |
R4693 |
T5418 |
T5420 |
nummod |
72,C |
R4694 |
T5419 |
T5420 |
compound |
°,C |
R4695 |
T5420 |
T5417 |
pobj |
C,of |
R4696 |
T5421 |
T5401 |
prep |
for,using |
R4697 |
T5422 |
T5423 |
nummod |
10,min |
R4698 |
T5423 |
T5421 |
pobj |
min,for |
R4699 |
T5424 |
T5423 |
punct |
",",min |
R470 |
T640 |
T633 |
appos |
inhibitor,phosphatase-1 |
R4700 |
T5425 |
T5426 |
nummod |
35,cycles |
R4701 |
T5426 |
T5423 |
appos |
cycles,min |
R4702 |
T5427 |
T5401 |
prep |
at,using |
R4703 |
T5428 |
T5429 |
nummod |
94,° |
R4704 |
T5429 |
T5427 |
pobj |
°,at |
R4705 |
T5430 |
T5401 |
dobj |
C,using |
R4706 |
T5431 |
T5401 |
prep |
for,using |
R4707 |
T5432 |
T5433 |
nummod |
45,s |
R4708 |
T5433 |
T5431 |
pobj |
s,for |
R4709 |
T5434 |
T5433 |
punct |
",",s |
R471 |
T523 |
T522 |
prep |
on,effects |
R4710 |
T5435 |
T5437 |
nummod |
52,C |
R4711 |
T5436 |
T5437 |
compound |
°,C |
R4712 |
T5437 |
T5433 |
appos |
C,s |
R4713 |
T5438 |
T5401 |
prep |
for,using |
R4714 |
T5439 |
T5438 |
pobj |
45,for |
R4715 |
T5440 |
T5401 |
dobj |
s,using |
R4716 |
T5441 |
T5440 |
punct |
",",s |
R4717 |
T5442 |
T5444 |
nummod |
72,C |
R4718 |
T5443 |
T5444 |
compound |
°,C |
R4719 |
T5444 |
T5440 |
appos |
C,s |
R472 |
T641 |
T640 |
prep |
of,inhibitor |
R4720 |
T5445 |
T5401 |
prep |
for,using |
R4721 |
T5446 |
T5447 |
nummod |
45,s. |
R4722 |
T5447 |
T5445 |
pobj |
s.,for |
R473 |
T642 |
T643 |
nummod |
p38,MAPK |
R474 |
T524 |
T523 |
pobj |
GATA-3,on |
R475 |
T643 |
T641 |
pobj |
MAPK,of |
R476 |
T644 |
T643 |
punct |
",",MAPK |
R477 |
T645 |
T646 |
nsubj |
which,is |
R478 |
T646 |
T643 |
relcl |
is,MAPK |
R479 |
T525 |
T512 |
conj |
are,are |
R480 |
T647 |
T646 |
acomp |
necessary,is |
R481 |
T648 |
T647 |
prep |
for,necessary |
R482 |
T526 |
T525 |
acomp |
unknown,are |
R483 |
T527 |
T525 |
punct |
.,are |
R484 |
T528 |
T529 |
nsubj |
We,investigated |
R485 |
T529 |
T529 |
ROOT |
investigated,investigated |
R486 |
T649 |
T651 |
amod |
GATA-3,translocation |
R487 |
T530 |
T531 |
det |
the,effect |
R488 |
T531 |
T529 |
dobj |
effect,investigated |
R489 |
T532 |
T531 |
prep |
of,effect |
R490 |
T533 |
T536 |
det |
the,propionate |
R491 |
T534 |
T536 |
amod |
corticosteroid,propionate |
R492 |
T650 |
T651 |
amod |
nuclear,translocation |
R493 |
T535 |
T536 |
compound |
fluticasone,propionate |
R494 |
T536 |
T532 |
pobj |
propionate,of |
R495 |
T537 |
T536 |
prep |
on,propionate |
R496 |
T538 |
T539 |
amod |
GATA-3,regulation |
R497 |
T539 |
T537 |
pobj |
regulation,on |
R4970 |
T5754 |
T5754 |
ROOT |
GR-GATA-3,GR-GATA-3 |
R4971 |
T5755 |
T5778 |
prep |
In,separated |
R4972 |
T5756 |
T5758 |
compound |
Vitro,Assay |
R4973 |
T5757 |
T5758 |
compound |
Competition,Assay |
R4974 |
T5758 |
T5755 |
pobj |
Assay,In |
R4975 |
T5759 |
T5758 |
prep |
for,Assay |
R4976 |
T5760 |
T5759 |
pobj |
Importin-α,for |
R4977 |
T5761 |
T5760 |
punct |
(,Importin-α |
R4978 |
T5762 |
T5763 |
compound |
Far-Western,ELISA |
R4979 |
T5763 |
T5760 |
appos |
ELISA,Importin-α |
R498 |
T540 |
T539 |
prep |
in,regulation |
R4980 |
T5764 |
T5760 |
punct |
),Importin-α |
R4981 |
T5765 |
T5766 |
compound |
Immunoprecipitated,importin-α |
R4982 |
T5766 |
T5778 |
nsubjpass |
importin-α,separated |
R4983 |
T5767 |
T5772 |
punct |
(,Biotechnology |
R4984 |
T5768 |
T5772 |
npadvmod |
anti-importin-α,Biotechnology |
R4985 |
T5769 |
T5772 |
punct |
",",Biotechnology |
R4986 |
T5770 |
T5771 |
compound |
Santa,Cruz |
R4987 |
T5771 |
T5772 |
compound |
Cruz,Biotechnology |
R4988 |
T5772 |
T5766 |
appos |
Biotechnology,importin-α |
R4989 |
T5773 |
T5772 |
punct |
),Biotechnology |
R499 |
T651 |
T648 |
pobj |
translocation,for |
R4990 |
T5774 |
T5772 |
prep |
from,Biotechnology |
R4991 |
T5775 |
T5776 |
amod |
HuT-78,cells |
R4992 |
T5776 |
T5774 |
pobj |
cells,from |
R4993 |
T5777 |
T5778 |
auxpass |
was,separated |
R4994 |
T5778 |
T5778 |
ROOT |
separated,separated |
R4995 |
T5779 |
T5778 |
agent |
by,separated |
R4996 |
T5780 |
T5779 |
pobj |
SDS-PAGE,by |
R4997 |
T5781 |
T5778 |
cc |
and,separated |
R4998 |
T5782 |
T5778 |
conj |
purified,separated |
R4999 |
T5783 |
T5782 |
prep |
from,purified |
R500 |
T541 |
T542 |
amod |
human,T-lymphocytes |
R5000 |
T5784 |
T5786 |
det |
the,gel |
R5001 |
T5785 |
T5786 |
amod |
excised,gel |
R5002 |
T5786 |
T5783 |
pobj |
gel,from |
R5003 |
T5787 |
T5786 |
prep |
by,gel |
R5004 |
T5788 |
T5789 |
compound |
electroelution,[ |
R5005 |
T5789 |
T5787 |
pobj |
[,by |
R5006 |
T5790 |
T5791 |
nummod |
36,] |
R5007 |
T5791 |
T5789 |
appos |
],[ |
R5008 |
T5792 |
T5778 |
punct |
.,separated |
R5009 |
T5793 |
T5796 |
advmod |
Similarly,was |
R501 |
T542 |
T540 |
pobj |
T-lymphocytes,in |
R5010 |
T5794 |
T5796 |
punct |
",",was |
R5011 |
T5795 |
T5796 |
nsubj |
GATA-3,was |
R5012 |
T5796 |
T5796 |
ROOT |
was,was |
R5013 |
T5797 |
T5796 |
acomp |
isolated,was |
R5014 |
T5798 |
T5797 |
prep |
from,isolated |
R5015 |
T5799 |
T5801 |
amod |
nonstimulated,cells |
R5016 |
T5800 |
T5801 |
amod |
HuT-78,cells |
R5017 |
T5801 |
T5798 |
pobj |
cells,from |
R5018 |
T5802 |
T5801 |
cc |
or,cells |
R5019 |
T5803 |
T5801 |
conj |
cells,cells |
R502 |
T543 |
T539 |
prep |
in,regulation |
R5020 |
T5804 |
T5796 |
conj |
stimulated,was |
R5021 |
T5805 |
T5804 |
prep |
for,stimulated |
R5022 |
T5806 |
T5807 |
nummod |
30,min |
R5023 |
T5807 |
T5805 |
pobj |
min,for |
R5024 |
T5808 |
T5807 |
prep |
with,min |
R5025 |
T5809 |
T5810 |
compound |
anti-CD3,/ |
R5026 |
T5810 |
T5808 |
pobj |
/,with |
R5027 |
T5811 |
T5810 |
nummod |
CD28,/ |
R5028 |
T5812 |
T5810 |
cc |
and,/ |
R5029 |
T5813 |
T5814 |
nsubj |
GR,was |
R503 |
T544 |
T543 |
pobj |
vitro,in |
R5030 |
T5814 |
T5796 |
conj |
was,was |
R5031 |
T5815 |
T5814 |
acomp |
isolated,was |
R5032 |
T5816 |
T5815 |
prep |
from,isolated |
R5033 |
T5817 |
T5816 |
pobj |
FP,from |
R5034 |
T5818 |
T5817 |
punct |
(,FP |
R5035 |
T5819 |
T5820 |
nummod |
10,− |
R5036 |
T5820 |
T5817 |
appos |
−,FP |
R5037 |
T5821 |
T5822 |
nummod |
8,M |
R5038 |
T5822 |
T5817 |
conj |
M,FP |
R5039 |
T5823 |
T5822 |
punct |
",",M |
R504 |
T545 |
T543 |
cc |
and,in |
R5040 |
T5824 |
T5825 |
nummod |
30,min |
R5041 |
T5825 |
T5822 |
appos |
min,M |
R5042 |
T5826 |
T5822 |
punct |
),M |
R5043 |
T5827 |
T5814 |
conj |
stimulated,was |
R5044 |
T5828 |
T5829 |
amod |
HuT-78,cells |
R5045 |
T5829 |
T5827 |
dobj |
cells,stimulated |
R5046 |
T5830 |
T5814 |
punct |
.,was |
R5047 |
T5831 |
T5832 |
det |
These,proteins |
R5048 |
T5832 |
T5835 |
nsubjpass |
proteins,refolded |
R5049 |
T5833 |
T5835 |
auxpass |
were,refolded |
R505 |
T652 |
T623 |
punct |
.,induces |
R5050 |
T5834 |
T5835 |
advmod |
subsequently,refolded |
R5051 |
T5835 |
T5835 |
ROOT |
refolded,refolded |
R5052 |
T5836 |
T5835 |
prep |
in,refolded |
R5053 |
T5837 |
T5838 |
amod |
glycine,solution |
R5054 |
T5838 |
T5836 |
pobj |
solution,in |
R5055 |
T5839 |
T5835 |
punct |
.,refolded |
R5056 |
T5840 |
T5841 |
nummod |
100,µl |
R5057 |
T5841 |
T5852 |
nsubjpass |
µl,added |
R5058 |
T5842 |
T5841 |
prep |
of,µl |
R5059 |
T5843 |
T5844 |
amod |
importin-α,solution |
R506 |
T546 |
T543 |
conj |
in,in |
R5060 |
T5844 |
T5842 |
pobj |
solution,of |
R5061 |
T5845 |
T5844 |
punct |
(,solution |
R5062 |
T5846 |
T5847 |
nummod |
100,ng/ml |
R5063 |
T5847 |
T5844 |
appos |
ng/ml,solution |
R5064 |
T5848 |
T5847 |
prep |
in,ng/ml |
R5065 |
T5849 |
T5848 |
pobj |
TBS,in |
R5066 |
T5850 |
T5844 |
punct |
),solution |
R5067 |
T5851 |
T5852 |
auxpass |
was,added |
R5068 |
T5852 |
T5852 |
ROOT |
added,added |
R5069 |
T5853 |
T5852 |
prep |
to,added |
R507 |
T653 |
T655 |
det |
These,effects |
R5070 |
T5854 |
T5853 |
pobj |
96-well,to |
R5071 |
T5855 |
T5854 |
dobj |
plates,96-well |
R5072 |
T5856 |
T5855 |
acl |
coated,plates |
R5073 |
T5857 |
T5856 |
prep |
with,coated |
R5074 |
T5858 |
T5860 |
amod |
goat,antibody |
R5075 |
T5859 |
T5860 |
amod |
anti-importin-α,antibody |
R5076 |
T5860 |
T5857 |
pobj |
antibody,with |
R5077 |
T5861 |
T5852 |
punct |
.,added |
R5078 |
T5862 |
T5880 |
prep |
After,added |
R5079 |
T5863 |
T5865 |
nummod |
1,incubation |
R508 |
T547 |
T546 |
pobj |
vivo,in |
R5080 |
T5864 |
T5865 |
compound |
h,incubation |
R5081 |
T5865 |
T5862 |
pobj |
incubation,After |
R5082 |
T5866 |
T5880 |
punct |
",",added |
R5083 |
T5867 |
T5880 |
nsubjpass |
GATA-3,added |
R5084 |
T5868 |
T5870 |
punct |
(,ng/ml |
R5085 |
T5869 |
T5870 |
nummod |
100,ng/ml |
R5086 |
T5870 |
T5867 |
appos |
ng/ml,GATA-3 |
R5087 |
T5871 |
T5870 |
prep |
in,ng/ml |
R5088 |
T5872 |
T5871 |
pobj |
TBS,in |
R5089 |
T5873 |
T5870 |
punct |
),ng/ml |
R509 |
T654 |
T655 |
amod |
inhibitory,effects |
R5090 |
T5874 |
T5870 |
prep |
from,ng/ml |
R5091 |
T5875 |
T5878 |
amod |
stimulated,cells |
R5092 |
T5876 |
T5875 |
cc |
or,stimulated |
R5093 |
T5877 |
T5875 |
conj |
unstimulated,stimulated |
R5094 |
T5878 |
T5874 |
pobj |
cells,from |
R5095 |
T5879 |
T5880 |
auxpass |
were,added |
R5096 |
T5880 |
T5880 |
ROOT |
added,added |
R5097 |
T5881 |
T5880 |
prep |
to,added |
R5098 |
T5882 |
T5884 |
det |
the,wells |
R5099 |
T5883 |
T5884 |
amod |
importin-α-coated,wells |
R510 |
T655 |
T658 |
nsubj |
effects,are |
R5100 |
T5884 |
T5881 |
pobj |
wells,to |
R5101 |
T5885 |
T5880 |
punct |
.,added |
R5102 |
T5886 |
T5901 |
nsubjpass |
GR,added |
R5103 |
T5887 |
T5886 |
punct |
(,GR |
R5104 |
T5888 |
T5891 |
nummod |
10,ng/ml |
R5105 |
T5889 |
T5888 |
cc |
or,10 |
R5106 |
T5890 |
T5888 |
conj |
100,10 |
R5107 |
T5891 |
T5886 |
appos |
ng/ml,GR |
R5108 |
T5892 |
T5891 |
prep |
in,ng/ml |
R5109 |
T5893 |
T5892 |
pobj |
TBS,in |
R511 |
T548 |
T529 |
punct |
.,investigated |
R5110 |
T5894 |
T5891 |
punct |
),ng/ml |
R5111 |
T5895 |
T5891 |
prep |
from,ng/ml |
R5112 |
T5896 |
T5899 |
amod |
stimulated,cells |
R5113 |
T5897 |
T5896 |
cc |
or,stimulated |
R5114 |
T5898 |
T5896 |
conj |
unstimulated,stimulated |
R5115 |
T5899 |
T5895 |
pobj |
cells,from |
R5116 |
T5900 |
T5901 |
auxpass |
were,added |
R5117 |
T5901 |
T5901 |
ROOT |
added,added |
R5118 |
T5902 |
T5901 |
prep |
to,added |
R5119 |
T5903 |
T5904 |
det |
some,wells |
R512 |
T549 |
T549 |
ROOT |
Methods,Methods |
R5120 |
T5904 |
T5902 |
pobj |
wells,to |
R5121 |
T5905 |
T5901 |
punct |
.,added |
R5122 |
T5906 |
T5916 |
prep |
After,washed |
R5123 |
T5907 |
T5911 |
det |
a,incubation |
R5124 |
T5908 |
T5911 |
amod |
further,incubation |
R5125 |
T5909 |
T5910 |
nummod |
1,h |
R5126 |
T5910 |
T5911 |
compound |
h,incubation |
R5127 |
T5911 |
T5906 |
pobj |
incubation,After |
R5128 |
T5912 |
T5916 |
punct |
",",washed |
R5129 |
T5913 |
T5914 |
det |
the,plate |
R513 |
T656 |
T655 |
prep |
of,effects |
R5130 |
T5914 |
T5916 |
nsubjpass |
plate,washed |
R5131 |
T5915 |
T5916 |
auxpass |
was,washed |
R5132 |
T5916 |
T5916 |
ROOT |
washed,washed |
R5133 |
T5917 |
T5916 |
cc |
and,washed |
R5134 |
T5918 |
T5916 |
conj |
incubated,washed |
R5135 |
T5919 |
T5918 |
prep |
with,incubated |
R5136 |
T5920 |
T5921 |
amod |
primary,antibodies |
R5137 |
T5921 |
T5919 |
pobj |
antibodies,with |
R5138 |
T5922 |
T5921 |
punct |
(,antibodies |
R5139 |
T5923 |
T5924 |
det |
a,mixture |
R514 |
T550 |
T549 |
cc |
and,Methods |
R5140 |
T5924 |
T5921 |
appos |
mixture,antibodies |
R5141 |
T5925 |
T5924 |
prep |
of,mixture |
R5142 |
T5926 |
T5927 |
compound |
rabbit,anti-GATA-3 |
R5143 |
T5927 |
T5925 |
pobj |
anti-GATA-3,of |
R5144 |
T5928 |
T5927 |
cc |
and,anti-GATA-3 |
R5145 |
T5929 |
T5927 |
conj |
mouse,anti-GATA-3 |
R5146 |
T5930 |
T5927 |
conj |
anti-GR,anti-GATA-3 |
R5147 |
T5931 |
T5930 |
punct |
",",anti-GR |
R5148 |
T5932 |
T5934 |
compound |
Santa,Biotechnology |
R5149 |
T5933 |
T5934 |
compound |
Cruz,Biotechnology |
R515 |
T657 |
T656 |
pobj |
fluticasone,of |
R5150 |
T5934 |
T5927 |
appos |
Biotechnology,anti-GATA-3 |
R5151 |
T5935 |
T5921 |
punct |
),antibodies |
R5152 |
T5936 |
T5918 |
prep |
for,incubated |
R5153 |
T5937 |
T5938 |
nummod |
1.5,h |
R5154 |
T5938 |
T5936 |
pobj |
h,for |
R5155 |
T5939 |
T5918 |
punct |
",",incubated |
R5156 |
T5940 |
T5918 |
cc |
and,incubated |
R5157 |
T5941 |
T5942 |
advmod |
then,incubated |
R5158 |
T5942 |
T5918 |
conj |
incubated,incubated |
R5159 |
T5943 |
T5942 |
prep |
with,incubated |
R516 |
T658 |
T658 |
ROOT |
are,are |
R5160 |
T5944 |
T5945 |
amod |
secondary,antibodies |
R5161 |
T5945 |
T5943 |
pobj |
antibodies,with |
R5162 |
T5946 |
T5916 |
punct |
.,washed |
R5163 |
T5947 |
T5948 |
nummod |
FITC,swine |
R5164 |
T5948 |
T5949 |
nsubj |
swine,anti-rabbit |
R5165 |
T5949 |
T5959 |
nsubjpass |
anti-rabbit,used |
R5166 |
T5950 |
T5949 |
dobj |
IgG,anti-rabbit |
R5167 |
T5951 |
T5952 |
punct |
(,Dako |
R5168 |
T5952 |
T5950 |
appos |
Dako,IgG |
R5169 |
T5953 |
T5952 |
punct |
",",Dako |
R517 |
T659 |
T658 |
acomp |
rapid,are |
R5170 |
T5954 |
T5952 |
npadvmod |
Cambridge,Dako |
R5171 |
T5955 |
T5954 |
punct |
",",Cambridge |
R5172 |
T5956 |
T5954 |
appos |
UK,Cambridge |
R5173 |
T5957 |
T5954 |
punct |
),Cambridge |
R5174 |
T5958 |
T5959 |
auxpass |
was,used |
R5175 |
T5959 |
T5959 |
ROOT |
used,used |
R5176 |
T5960 |
T5959 |
prep |
for,used |
R5177 |
T5961 |
T5962 |
det |
the,detection |
R5178 |
T5962 |
T5960 |
pobj |
detection,for |
R5179 |
T5963 |
T5962 |
prep |
of,detection |
R518 |
T551 |
T549 |
conj |
Findings,Methods |
R5180 |
T5964 |
T5963 |
pobj |
GATA-3,of |
R5181 |
T5965 |
T5959 |
punct |
",",used |
R5182 |
T5966 |
T5959 |
cc |
and,used |
R5183 |
T5967 |
T5968 |
compound |
rhodamine,donkey |
R5184 |
T5968 |
T5981 |
nsubjpass |
donkey,used |
R5185 |
T5969 |
T5970 |
compound |
anti-mouse,IgG |
R5186 |
T5970 |
T5981 |
nsubjpass |
IgG,used |
R5187 |
T5971 |
T5972 |
punct |
(,Novus |
R5188 |
T5972 |
T5970 |
appos |
Novus,IgG |
R5189 |
T5973 |
T5972 |
punct |
",",Novus |
R519 |
T660 |
T659 |
punct |
",",rapid |
R5190 |
T5974 |
T5972 |
npadvmod |
Littleton,Novus |
R5191 |
T5975 |
T5974 |
punct |
",",Littleton |
R5192 |
T5976 |
T5974 |
conj |
Colorado,Littleton |
R5193 |
T5977 |
T5976 |
punct |
",",Colorado |
R5194 |
T5978 |
T5976 |
conj |
USA,Colorado |
R5195 |
T5979 |
T5976 |
punct |
),Colorado |
R5196 |
T5980 |
T5981 |
auxpass |
was,used |
R5197 |
T5981 |
T5959 |
conj |
used,used |
R5198 |
T5982 |
T5981 |
prep |
for,used |
R5199 |
T5983 |
T5984 |
det |
the,detection |
R520 |
T661 |
T659 |
conj |
potent,rapid |
R5200 |
T5984 |
T5982 |
pobj |
detection,for |
R5201 |
T5985 |
T5984 |
prep |
of,detection |
R5202 |
T5986 |
T5985 |
pobj |
GR,of |
R5203 |
T5987 |
T5981 |
punct |
.,used |
R5204 |
T5988 |
T5991 |
nmod |
FITC,levels |
R5205 |
T5989 |
T5988 |
cc |
and,FITC |
R5206 |
T5990 |
T5988 |
conj |
rhodamine,FITC |
R5207 |
T5991 |
T5993 |
nsubjpass |
levels,measured |
R5208 |
T5992 |
T5993 |
auxpass |
were,measured |
R5209 |
T5993 |
T5993 |
ROOT |
measured,measured |
R521 |
T662 |
T658 |
punct |
",",are |
R5210 |
T5994 |
T5993 |
prep |
with,measured |
R5211 |
T5995 |
T5998 |
det |
a,reader |
R5212 |
T5996 |
T5998 |
amod |
fluorescent,reader |
R5213 |
T5997 |
T5998 |
amod |
micro-plate,reader |
R5214 |
T5998 |
T5994 |
pobj |
reader,with |
R5215 |
T5999 |
T5998 |
punct |
(,reader |
R5216 |
T6000 |
T5998 |
appos |
Bioline,reader |
R5217 |
T6001 |
T6000 |
punct |
",",Bioline |
R5218 |
T6002 |
T6000 |
conj |
London,Bioline |
R5219 |
T6003 |
T6002 |
punct |
",",London |
R522 |
T552 |
T574 |
prep |
In,demonstrated |
R5220 |
T6004 |
T6002 |
conj |
UK,London |
R5221 |
T6005 |
T5998 |
punct |
),reader |
R5222 |
T6006 |
T5993 |
punct |
.,measured |
R523 |
T663 |
T658 |
cc |
and,are |
R524 |
T664 |
T658 |
conj |
prolonged,are |
R525 |
T665 |
T658 |
punct |
.,are |
R526 |
T553 |
T557 |
det |
a,line |
R527 |
T666 |
T668 |
nsubj |
We,demonstrated |
R528 |
T667 |
T668 |
advmod |
also,demonstrated |
R529 |
T554 |
T557 |
compound |
T,line |
R530 |
T668 |
T668 |
ROOT |
demonstrated,demonstrated |
R5304 |
T6161 |
T6163 |
compound |
NF-κB,NF-κB |
R5305 |
T6162 |
T6163 |
compound |
Activation,NF-κB |
R5306 |
T6163 |
T6170 |
nsubjpass |
NF-κB,determined |
R5307 |
T6164 |
T6165 |
amod |
binding,activity |
R5308 |
T6165 |
T6163 |
dobj |
activity,NF-κB |
R5309 |
T6166 |
T6165 |
prep |
in,activity |
R531 |
T669 |
T672 |
mark |
that,inhibits |
R5310 |
T6167 |
T6168 |
amod |
nuclear,extracts |
R5311 |
T6168 |
T6166 |
pobj |
extracts,in |
R5312 |
T6169 |
T6170 |
auxpass |
was,determined |
R5313 |
T6170 |
T6170 |
ROOT |
determined,determined |
R5314 |
T6171 |
T6170 |
advcl |
using,determined |
R5315 |
T6172 |
T6174 |
det |
an,kit |
R5316 |
T6173 |
T6174 |
amod |
ELISA-based,kit |
R5317 |
T6174 |
T6171 |
dobj |
kit,using |
R5318 |
T6175 |
T6174 |
punct |
(,kit |
R5319 |
T6176 |
T6177 |
amod |
Trans-AM,p65 |
R532 |
T670 |
T671 |
amod |
inhaled,fluticasone |
R5320 |
T6177 |
T6174 |
appos |
p65,kit |
R5321 |
T6178 |
T6177 |
punct |
",",p65 |
R5322 |
T6179 |
T6180 |
compound |
Active,Motif |
R5323 |
T6180 |
T6177 |
appos |
Motif,p65 |
R5324 |
T6181 |
T6180 |
punct |
",",Motif |
R5325 |
T6182 |
T6180 |
conj |
Rixensart,Motif |
R5326 |
T6183 |
T6182 |
punct |
",",Rixensart |
R5327 |
T6184 |
T6182 |
conj |
Belgium,Rixensart |
R5328 |
T6185 |
T6174 |
punct |
),kit |
R5329 |
T6186 |
T6170 |
punct |
.,determined |
R533 |
T671 |
T672 |
nsubj |
fluticasone,inhibits |
R5330 |
T6187 |
T6196 |
prep |
In,incubated |
R5331 |
T6188 |
T6187 |
pobj |
brief,In |
R5332 |
T6189 |
T6196 |
punct |
",",incubated |
R5333 |
T6190 |
T6191 |
nummod |
5,µg |
R5334 |
T6191 |
T6196 |
nsubjpass |
µg,incubated |
R5335 |
T6192 |
T6191 |
prep |
of,µg |
R5336 |
T6193 |
T6194 |
amod |
nuclear,extracts |
R5337 |
T6194 |
T6192 |
pobj |
extracts,of |
R5338 |
T6195 |
T6196 |
auxpass |
were,incubated |
R5339 |
T6196 |
T6196 |
ROOT |
incubated,incubated |
R534 |
T555 |
T557 |
compound |
lymphocyte,line |
R5340 |
T6197 |
T6196 |
prep |
with,incubated |
R5341 |
T6198 |
T6199 |
det |
a,plate |
R5342 |
T6199 |
T6197 |
pobj |
plate,with |
R5343 |
T6200 |
T6199 |
acl |
coated,plate |
R5344 |
T6201 |
T6200 |
prep |
with,coated |
R5345 |
T6202 |
T6204 |
det |
an,consensus |
R5346 |
T6203 |
T6204 |
amod |
NF-κB,consensus |
R5347 |
T6204 |
T6205 |
compound |
consensus,oligonucleotide |
R5348 |
T6205 |
T6201 |
pobj |
oligonucleotide,with |
R5349 |
T6206 |
T6196 |
punct |
.,incubated |
R535 |
T672 |
T668 |
ccomp |
inhibits,demonstrated |
R5350 |
T6207 |
T6209 |
nsubjpass |
Plates,washed |
R5351 |
T6208 |
T6209 |
auxpass |
were,washed |
R5352 |
T6209 |
T6209 |
ROOT |
washed,washed |
R5353 |
T6210 |
T6209 |
prep |
before,washed |
R5354 |
T6211 |
T6210 |
pobj |
addition,before |
R5355 |
T6212 |
T6211 |
prep |
of,addition |
R5356 |
T6213 |
T6215 |
det |
an,antibody |
R5357 |
T6214 |
T6215 |
amod |
anti-p65,antibody |
R5358 |
T6215 |
T6212 |
pobj |
antibody,of |
R5359 |
T6216 |
T6209 |
punct |
.,washed |
R536 |
T673 |
T675 |
amod |
GATA-3,translocation |
R5360 |
T6217 |
T6218 |
compound |
Antibody,binding |
R5361 |
T6218 |
T6220 |
nsubjpass |
binding,detected |
R5362 |
T6219 |
T6220 |
auxpass |
was,detected |
R5363 |
T6220 |
T6220 |
ROOT |
detected,detected |
R5364 |
T6221 |
T6220 |
prep |
with,detected |
R5365 |
T6222 |
T6225 |
det |
a,antibody |
R5366 |
T6223 |
T6225 |
amod |
secondary,antibody |
R5367 |
T6224 |
T6225 |
amod |
HRP-conjugated,antibody |
R5368 |
T6225 |
T6221 |
pobj |
antibody,with |
R5369 |
T6226 |
T6220 |
cc |
and,detected |
R537 |
T556 |
T557 |
compound |
cell,line |
R5370 |
T6227 |
T6220 |
conj |
developed,detected |
R5371 |
T6228 |
T6227 |
prep |
with,developed |
R5372 |
T6229 |
T6230 |
compound |
TMB,substrate |
R5373 |
T6230 |
T6228 |
pobj |
substrate,with |
R5374 |
T6231 |
T6220 |
punct |
.,detected |
R5375 |
T6232 |
T6233 |
det |
The,intensity |
R5376 |
T6233 |
T6238 |
nsubjpass |
intensity,measured |
R5377 |
T6234 |
T6233 |
prep |
of,intensity |
R5378 |
T6235 |
T6236 |
det |
the,reaction |
R5379 |
T6236 |
T6234 |
pobj |
reaction,of |
R538 |
T674 |
T675 |
amod |
nuclear,translocation |
R5380 |
T6237 |
T6238 |
auxpass |
was,measured |
R5381 |
T6238 |
T6238 |
ROOT |
measured,measured |
R5382 |
T6239 |
T6238 |
prep |
at,measured |
R5383 |
T6240 |
T6241 |
nummod |
450,nm |
R5384 |
T6241 |
T6239 |
pobj |
nm,at |
R5385 |
T6242 |
T6238 |
punct |
.,measured |
R539 |
T675 |
T672 |
dobj |
translocation,inhibits |
R540 |
T676 |
T675 |
prep |
in,translocation |
R541 |
T557 |
T552 |
pobj |
line,In |
R542 |
T677 |
T679 |
amod |
peripheral,lymphocytes |
R543 |
T678 |
T679 |
compound |
blood,lymphocytes |
R544 |
T679 |
T676 |
pobj |
lymphocytes,in |
R545 |
T558 |
T559 |
punct |
(,HuT-78 |
R546 |
T680 |
T679 |
prep |
of,lymphocytes |
R547 |
T681 |
T680 |
pobj |
patients,of |
R548 |
T559 |
T565 |
amod |
HuT-78,cells |
R549 |
T682 |
T672 |
prep |
with,inhibits |
R550 |
T560 |
T559 |
punct |
),HuT-78 |
R551 |
T561 |
T559 |
cc |
and,HuT-78 |
R552 |
T562 |
T565 |
amod |
peripheral,cells |
R553 |
T563 |
T564 |
compound |
blood,mononuclear |
R554 |
T683 |
T682 |
pobj |
asthma,with |
R555 |
T684 |
T683 |
prep |
in,asthma |
R556 |
T564 |
T565 |
compound |
mononuclear,cells |
R557 |
T685 |
T684 |
pobj |
vivo,in |
R558 |
T686 |
T668 |
punct |
.,demonstrated |
R559 |
T687 |
T688 |
compound |
Conclusions,Corticosteroids |
R5594 |
T6486 |
T6488 |
compound |
Immunofluorescence,Immunofluorescence |
R5595 |
T6487 |
T6488 |
compound |
Staining,Immunofluorescence |
R5596 |
T6488 |
T6491 |
nsubjpass |
Immunofluorescence,performed |
R5597 |
T6489 |
T6488 |
acl |
staining,Immunofluorescence |
R5598 |
T6490 |
T6491 |
auxpass |
was,performed |
R5599 |
T6491 |
T6491 |
ROOT |
performed,performed |
R560 |
T688 |
T689 |
nsubj |
Corticosteroids,have |
R5600 |
T6492 |
T6494 |
mark |
as,described |
R5601 |
T6493 |
T6494 |
advmod |
previously,described |
R5602 |
T6494 |
T6491 |
advcl |
described,performed |
R5603 |
T6495 |
T6497 |
nmod |
[,] |
R5604 |
T6496 |
T6497 |
nummod |
34,] |
R5605 |
T6497 |
T6494 |
dobj |
],described |
R5606 |
T6498 |
T6491 |
punct |
.,performed |
R5607 |
T6499 |
T6500 |
det |
All,staining |
R5608 |
T6500 |
T6502 |
nsubjpass |
staining,performed |
R5609 |
T6501 |
T6502 |
auxpass |
was,performed |
R561 |
T689 |
T689 |
ROOT |
have,have |
R5610 |
T6502 |
T6502 |
ROOT |
performed,performed |
R5611 |
T6503 |
T6502 |
prep |
at,performed |
R5612 |
T6504 |
T6505 |
compound |
room,temperature |
R5613 |
T6505 |
T6503 |
pobj |
temperature,at |
R5614 |
T6506 |
T6503 |
cc |
and,at |
R5615 |
T6507 |
T6503 |
conj |
under,at |
R5616 |
T6508 |
T6507 |
pobj |
humidification,under |
R5617 |
T6509 |
T6502 |
punct |
.,performed |
R5618 |
T6510 |
T6512 |
nsubjpass |
Cells,collected |
R5619 |
T6511 |
T6512 |
auxpass |
were,collected |
R562 |
T565 |
T574 |
nsubj |
cells,demonstrated |
R5620 |
T6512 |
T6512 |
ROOT |
collected,collected |
R5621 |
T6513 |
T6512 |
cc |
and,collected |
R5622 |
T6514 |
T6512 |
conj |
cytospins,collected |
R5623 |
T6515 |
T6514 |
acl |
prepared,cytospins |
R5624 |
T6516 |
T6515 |
prep |
in,prepared |
R5625 |
T6517 |
T6518 |
det |
a,cytocentrifuge |
R5626 |
T6518 |
T6516 |
pobj |
cytocentrifuge,in |
R5627 |
T6519 |
T6521 |
punct |
(,II |
R5628 |
T6520 |
T6521 |
compound |
Shandon,II |
R5629 |
T6521 |
T6518 |
appos |
II,cytocentrifuge |
R563 |
T690 |
T693 |
det |
a,effect |
R5630 |
T6522 |
T6521 |
punct |
",",II |
R5631 |
T6523 |
T6521 |
conj |
Shandon,II |
R5632 |
T6524 |
T6523 |
punct |
",",Shandon |
R5633 |
T6525 |
T6523 |
conj |
Runcorn,Shandon |
R5634 |
T6526 |
T6525 |
punct |
",",Runcorn |
R5635 |
T6527 |
T6525 |
conj |
UK,Runcorn |
R5636 |
T6528 |
T6521 |
punct |
),II |
R5637 |
T6529 |
T6512 |
punct |
.,collected |
R5638 |
T6530 |
T6532 |
nsubjpass |
Cells,permeabilized |
R5639 |
T6531 |
T6532 |
auxpass |
were,permeabilized |
R564 |
T691 |
T693 |
amod |
potent,effect |
R5640 |
T6532 |
T6532 |
ROOT |
permeabilized,permeabilized |
R5641 |
T6533 |
T6532 |
punct |
",",permeabilized |
R5642 |
T6534 |
T6532 |
conj |
blocked,permeabilized |
R5643 |
T6535 |
T6534 |
punct |
",",blocked |
R5644 |
T6536 |
T6532 |
cc |
and,permeabilized |
R5645 |
T6537 |
T6538 |
advmod |
then,incubated |
R5646 |
T6538 |
T6532 |
conj |
incubated,permeabilized |
R5647 |
T6539 |
T6538 |
prep |
with,incubated |
R5648 |
T6540 |
T6539 |
pobj |
GR,with |
R5649 |
T6541 |
T6542 |
punct |
(,1 |
R565 |
T566 |
T565 |
acl |
stimulated,cells |
R5650 |
T6542 |
T6548 |
nummod |
1,Biotechnology |
R5651 |
T6543 |
T6548 |
nummod |
∶,Biotechnology |
R5652 |
T6544 |
T6545 |
nummod |
50,E-20 |
R5653 |
T6545 |
T6548 |
compound |
E-20,Biotechnology |
R5654 |
T6546 |
T6547 |
compound |
Santa,Cruz |
R5655 |
T6547 |
T6548 |
compound |
Cruz,Biotechnology |
R5656 |
T6548 |
T6540 |
appos |
Biotechnology,GR |
R5657 |
T6549 |
T6538 |
punct |
),incubated |
R5658 |
T6550 |
T6538 |
cc |
or,incubated |
R5659 |
T6551 |
T6538 |
conj |
anti-GATA-3,incubated |
R566 |
T692 |
T693 |
amod |
inhibitory,effect |
R5660 |
T6552 |
T6559 |
punct |
(,antibody |
R5661 |
T6553 |
T6559 |
amod |
H-48,antibody |
R5662 |
T6554 |
T6559 |
punct |
;,antibody |
R5663 |
T6555 |
T6556 |
compound |
Santa,Cruz |
R5664 |
T6556 |
T6557 |
compound |
Cruz,Biotechnology |
R5665 |
T6557 |
T6559 |
compound |
Biotechnology,antibody |
R5666 |
T6558 |
T6557 |
punct |
),Biotechnology |
R5667 |
T6559 |
T6559 |
ROOT |
antibody,antibody |
R5668 |
T6560 |
T6559 |
prep |
for,antibody |
R5669 |
T6561 |
T6562 |
nummod |
1,h |
R567 |
T693 |
T689 |
dobj |
effect,have |
R5670 |
T6562 |
T6560 |
pobj |
h,for |
R5671 |
T6563 |
T6562 |
prep |
at,h |
R5672 |
T6564 |
T6565 |
compound |
room,temperature |
R5673 |
T6565 |
T6563 |
pobj |
temperature,at |
R5674 |
T6566 |
T6532 |
punct |
.,permeabilized |
R5675 |
T6567 |
T6579 |
prep |
After,incubated |
R5676 |
T6568 |
T6569 |
nummod |
three,washes |
R5677 |
T6569 |
T6567 |
pobj |
washes,After |
R5678 |
T6570 |
T6569 |
prep |
in,washes |
R5679 |
T6571 |
T6572 |
amod |
phosphate-buffered,saline |
R568 |
T694 |
T693 |
prep |
on,effect |
R5680 |
T6572 |
T6570 |
pobj |
saline,in |
R5681 |
T6573 |
T6574 |
punct |
(,PBS |
R5682 |
T6574 |
T6569 |
appos |
PBS,washes |
R5683 |
T6575 |
T6569 |
punct |
),washes |
R5684 |
T6576 |
T6579 |
punct |
",",incubated |
R5685 |
T6577 |
T6579 |
nsubjpass |
cells,incubated |
R5686 |
T6578 |
T6579 |
auxpass |
were,incubated |
R5687 |
T6579 |
T6579 |
ROOT |
incubated,incubated |
R5688 |
T6580 |
T6579 |
prep |
with,incubated |
R5689 |
T6581 |
T6582 |
amod |
tetrarhodamine,isothiocyanate |
R569 |
T567 |
T566 |
agent |
by,stimulated |
R5690 |
T6582 |
T6580 |
pobj |
isothiocyanate,with |
R5691 |
T6583 |
T6586 |
amod |
conjugated,antibody |
R5692 |
T6584 |
T6586 |
nmod |
goat,antibody |
R5693 |
T6585 |
T6586 |
amod |
anti-rabbit,antibody |
R5694 |
T6586 |
T6586 |
ROOT |
antibody,antibody |
R5695 |
T6587 |
T6588 |
punct |
(,Dako |
R5696 |
T6588 |
T6586 |
appos |
Dako,antibody |
R5697 |
T6589 |
T6588 |
punct |
),Dako |
R5698 |
T6590 |
T6586 |
punct |
.,antibody |
R5699 |
T6591 |
T6593 |
nsubjpass |
Cytospins,counterstained |
R570 |
T695 |
T694 |
pobj |
GATA-3,on |
R5700 |
T6592 |
T6593 |
auxpass |
were,counterstained |
R5701 |
T6593 |
T6593 |
ROOT |
counterstained,counterstained |
R5702 |
T6594 |
T6593 |
prep |
with,counterstained |
R5703 |
T6595 |
T6596 |
nummod |
4,′ |
R5704 |
T6596 |
T6600 |
nummod |
′,dihydrochloride |
R5705 |
T6597 |
T6599 |
punct |
",6",diamidino-2-phenylindole |
R5706 |
T6598 |
T6599 |
punct |
-,diamidino-2-phenylindole |
R5707 |
T6599 |
T6600 |
compound |
diamidino-2-phenylindole,dihydrochloride |
R5708 |
T6600 |
T6594 |
pobj |
dihydrochloride,with |
R5709 |
T6601 |
T6600 |
punct |
(,dihydrochloride |
R571 |
T696 |
T689 |
prep |
via,have |
R5710 |
T6602 |
T6600 |
appos |
DAPI,dihydrochloride |
R5711 |
T6603 |
T6600 |
punct |
),dihydrochloride |
R5712 |
T6604 |
T6600 |
punct |
",",dihydrochloride |
R5713 |
T6605 |
T6611 |
det |
a,stain |
R5714 |
T6606 |
T6611 |
amod |
fluorescent,stain |
R5715 |
T6607 |
T6609 |
amod |
blue,indole |
R5716 |
T6608 |
T6609 |
amod |
nuclear,indole |
R5717 |
T6609 |
T6611 |
compound |
indole,stain |
R5718 |
T6610 |
T6611 |
compound |
chromatin,stain |
R5719 |
T6611 |
T6600 |
appos |
stain,dihydrochloride |
R572 |
T568 |
T574 |
advcl |
anti-CD3,demonstrated |
R5720 |
T6612 |
T6593 |
punct |
",",counterstained |
R5721 |
T6613 |
T6593 |
cc |
and,counterstained |
R5722 |
T6614 |
T6593 |
conj |
mounted,counterstained |
R5723 |
T6615 |
T6614 |
prep |
in,mounted |
R5724 |
T6616 |
T6615 |
pobj |
PBS,in |
R5725 |
T6617 |
T6614 |
punct |
:,mounted |
R5726 |
T6618 |
T6614 |
conj |
glycerol,mounted |
R5727 |
T6619 |
T6618 |
punct |
(,glycerol |
R5728 |
T6620 |
T6621 |
nummod |
50,∶ |
R5729 |
T6621 |
T6618 |
appos |
∶,glycerol |
R573 |
T569 |
T568 |
cc |
and,anti-CD3 |
R5730 |
T6622 |
T6621 |
nummod |
50,∶ |
R5731 |
T6623 |
T6618 |
punct |
),glycerol |
R5732 |
T6624 |
T6593 |
punct |
.,counterstained |
R5733 |
T6625 |
T6627 |
det |
The,signal |
R5734 |
T6626 |
T6627 |
amod |
immunopositive,signal |
R5735 |
T6627 |
T6629 |
nsubjpass |
signal,characterised |
R5736 |
T6628 |
T6629 |
auxpass |
was,characterised |
R5737 |
T6629 |
T6629 |
ROOT |
characterised,characterised |
R5738 |
T6630 |
T6629 |
advcl |
using,characterised |
R5739 |
T6631 |
T6632 |
nmod |
laser,scanning |
R574 |
T570 |
T568 |
conj |
anti-CD28,anti-CD3 |
R5740 |
T6632 |
T6630 |
dobj |
scanning,using |
R5741 |
T6633 |
T6634 |
amod |
confocal,microscopy |
R5742 |
T6634 |
T6632 |
dobj |
microscopy,scanning |
R5743 |
T6635 |
T6632 |
prep |
on,scanning |
R5744 |
T6636 |
T6642 |
det |
a,cytometer |
R5745 |
T6637 |
T6639 |
nmod |
Leica,NT/SP |
R5746 |
T6638 |
T6639 |
compound |
TCS,NT/SP |
R5747 |
T6639 |
T6642 |
nmod |
NT/SP,cytometer |
R5748 |
T6640 |
T6642 |
amod |
interactive,cytometer |
R5749 |
T6641 |
T6642 |
compound |
laser,cytometer |
R575 |
T571 |
T574 |
prep |
in,demonstrated |
R5750 |
T6642 |
T6635 |
pobj |
cytometer,on |
R5751 |
T6643 |
T6642 |
acl |
equipped,cytometer |
R5752 |
T6644 |
T6643 |
prep |
with,equipped |
R5753 |
T6645 |
T6646 |
compound |
confocal,optics |
R5754 |
T6646 |
T6644 |
pobj |
optics,with |
R5755 |
T6647 |
T6646 |
punct |
(,optics |
R5756 |
T6648 |
T6649 |
compound |
Leica,Microsystems |
R5757 |
T6649 |
T6646 |
appos |
Microsystems,optics |
R5758 |
T6650 |
T6649 |
punct |
",",Microsystems |
R5759 |
T6651 |
T6649 |
conj |
Wetzlar,Microsystems |
R576 |
T697 |
T699 |
nummod |
two,mechanisms |
R5760 |
T6652 |
T6651 |
punct |
",",Wetzlar |
R5761 |
T6653 |
T6651 |
conj |
Germany,Wetzlar |
R5762 |
T6654 |
T6646 |
punct |
),optics |
R5763 |
T6655 |
T6629 |
punct |
.,characterised |
R5764 |
T6656 |
T6657 |
aux |
To,determine |
R5765 |
T6657 |
T6677 |
advcl |
determine,used |
R5766 |
T6658 |
T6659 |
det |
the,specificity |
R5767 |
T6659 |
T6657 |
dobj |
specificity,determine |
R5768 |
T6660 |
T6659 |
prep |
of,specificity |
R5769 |
T6661 |
T6662 |
det |
the,antibodies |
R577 |
T572 |
T571 |
pobj |
vitro,in |
R5770 |
T6662 |
T6660 |
pobj |
antibodies,of |
R5771 |
T6663 |
T6662 |
punct |
",",antibodies |
R5772 |
T6664 |
T6665 |
compound |
rabbit,serum |
R5773 |
T6665 |
T6666 |
compound |
serum,immunoglobulin |
R5774 |
T6666 |
T6659 |
conj |
immunoglobulin,specificity |
R5775 |
T6667 |
T6666 |
punct |
(,immunoglobulin |
R5776 |
T6668 |
T6666 |
appos |
Dako,immunoglobulin |
R5777 |
T6669 |
T6666 |
punct |
),immunoglobulin |
R5778 |
T6670 |
T6666 |
cc |
and,immunoglobulin |
R5779 |
T6671 |
T6672 |
amod |
secondary,antibodies |
R578 |
T698 |
T699 |
amod |
interacting,mechanisms |
R5780 |
T6672 |
T6666 |
conj |
antibodies,immunoglobulin |
R5781 |
T6673 |
T6657 |
prep |
without,determine |
R5782 |
T6674 |
T6675 |
det |
the,primary |
R5783 |
T6675 |
T6673 |
pobj |
primary,without |
R5784 |
T6676 |
T6677 |
auxpass |
were,used |
R5785 |
T6677 |
T6677 |
ROOT |
used,used |
R5786 |
T6678 |
T6677 |
prep |
as,used |
R5787 |
T6679 |
T6678 |
pobj |
controls,as |
R5788 |
T6680 |
T6677 |
punct |
.,used |
R5789 |
T6681 |
T6682 |
advmod |
Positively,stained |
R579 |
T699 |
T696 |
pobj |
mechanisms,via |
R5790 |
T6682 |
T6683 |
amod |
stained,nuclei |
R5791 |
T6683 |
T6688 |
nsubjpass |
nuclei,counted |
R5792 |
T6684 |
T6683 |
cc |
and,nuclei |
R5793 |
T6685 |
T6686 |
amod |
total,cells |
R5794 |
T6686 |
T6683 |
conj |
cells,nuclei |
R5795 |
T6687 |
T6688 |
auxpass |
were,counted |
R5796 |
T6688 |
T6688 |
ROOT |
counted,counted |
R5797 |
T6689 |
T6688 |
punct |
(,counted |
R5798 |
T6690 |
T6688 |
npadvmod |
500,counted |
R5799 |
T6691 |
T6688 |
punct |
),counted |
R580 |
T700 |
T702 |
nsubj |
that,suppress |
R5800 |
T6692 |
T6688 |
prep |
on,counted |
R5801 |
T6693 |
T6694 |
det |
each,slide |
R5802 |
T6694 |
T6692 |
pobj |
slide,on |
R5803 |
T6695 |
T6694 |
prep |
with,slide |
R5804 |
T6696 |
T6697 |
det |
the,observer |
R5805 |
T6697 |
T6695 |
pobj |
observer,with |
R5806 |
T6698 |
T6688 |
conj |
blinded,counted |
R5807 |
T6699 |
T6698 |
prep |
to,blinded |
R5808 |
T6700 |
T6701 |
det |
the,treatment |
R5809 |
T6701 |
T6699 |
pobj |
treatment,to |
R581 |
T573 |
T574 |
nsubj |
we,demonstrated |
R5810 |
T6702 |
T6688 |
punct |
.,counted |
R582 |
T701 |
T702 |
advmod |
potently,suppress |
R583 |
T702 |
T699 |
relcl |
suppress,mechanisms |
R584 |
T574 |
T574 |
ROOT |
demonstrated,demonstrated |
R585 |
T703 |
T705 |
amod |
Th2,expression |
R586 |
T704 |
T705 |
amod |
cytokine,expression |
R587 |
T705 |
T702 |
dobj |
expression,suppress |
R588 |
T575 |
T577 |
mark |
that,inhibits |
R589 |
T706 |
T689 |
punct |
.,have |
R590 |
T707 |
T709 |
det |
This,mechanism |
R591 |
T708 |
T709 |
amod |
novel,mechanism |
R592 |
T576 |
T577 |
nsubj |
fluticasone,inhibits |
R593 |
T709 |
T715 |
nsubj |
mechanism,account |
R594 |
T710 |
T709 |
prep |
of,mechanism |
R595 |
T711 |
T710 |
pobj |
action,of |
R5958 |
T6937 |
T6938 |
compound |
GATA-3-GFP,Construct |
R5959 |
T6938 |
T6948 |
nsubjpass |
Construct,obtained |
R596 |
T577 |
T574 |
ccomp |
inhibits,demonstrated |
R5960 |
T6939 |
T6941 |
det |
The,clone |
R5961 |
T6940 |
T6941 |
compound |
GATA-3,clone |
R5962 |
T6941 |
T6938 |
appos |
clone,Construct |
R5963 |
T6942 |
T6943 |
punct |
(,BC003070 |
R5964 |
T6943 |
T6941 |
appos |
BC003070,clone |
R5965 |
T6944 |
T6941 |
punct |
),clone |
R5966 |
T6945 |
T6946 |
amod |
complete,cDNA |
R5967 |
T6946 |
T6948 |
nsubjpass |
cDNA,obtained |
R5968 |
T6947 |
T6948 |
auxpass |
was,obtained |
R5969 |
T6948 |
T6948 |
ROOT |
obtained,obtained |
R597 |
T712 |
T711 |
prep |
of,action |
R5970 |
T6949 |
T6948 |
prep |
from,obtained |
R5971 |
T6950 |
T6952 |
compound |
Invitrogen,Technologies |
R5972 |
T6951 |
T6952 |
compound |
Life,Technologies |
R5973 |
T6952 |
T6949 |
pobj |
Technologies,from |
R5974 |
T6953 |
T6948 |
prep |
as,obtained |
R5975 |
T6954 |
T6962 |
det |
a,insert |
R5976 |
T6955 |
T6958 |
nummod |
5,EcoRI/3 |
R5977 |
T6956 |
T6958 |
punct |
′,EcoRI/3 |
R5978 |
T6957 |
T6958 |
punct |
-,EcoRI/3 |
R5979 |
T6958 |
T6962 |
compound |
EcoRI/3,insert |
R598 |
T713 |
T712 |
pobj |
corticosteroids,of |
R5980 |
T6959 |
T6961 |
punct |
′,XhoI |
R5981 |
T6960 |
T6961 |
punct |
-,XhoI |
R5982 |
T6961 |
T6962 |
compound |
XhoI,insert |
R5983 |
T6962 |
T6953 |
pobj |
insert,as |
R5984 |
T6963 |
T6962 |
prep |
of,insert |
R5985 |
T6964 |
T6963 |
pobj |
GATA-3,of |
R5986 |
T6965 |
T6962 |
prep |
in,insert |
R5987 |
T6966 |
T6968 |
det |
the,vector |
R5988 |
T6967 |
T6968 |
compound |
pOTB7,vector |
R5989 |
T6968 |
T6965 |
pobj |
vector,in |
R599 |
T714 |
T715 |
aux |
may,account |
R5990 |
T6969 |
T6948 |
punct |
.,obtained |
R5991 |
T6970 |
T6972 |
nsubjpass |
GATA-3,excised |
R5992 |
T6971 |
T6972 |
auxpass |
was,excised |
R5993 |
T6972 |
T6972 |
ROOT |
excised,excised |
R5994 |
T6973 |
T6972 |
prep |
from,excised |
R5995 |
T6974 |
T6973 |
pobj |
pOTB7,from |
R5996 |
T6975 |
T6972 |
advcl |
using,excised |
R5997 |
T6976 |
T6977 |
compound |
XhoI,digestion |
R5998 |
T6977 |
T6975 |
dobj |
digestion,using |
R5999 |
T6978 |
T6977 |
cc |
and,digestion |
R600 |
T578 |
T579 |
amod |
nuclear,translocation |
R6000 |
T6979 |
T6977 |
conj |
pEGFP-C2,digestion |
R6001 |
T6980 |
T6981 |
punct |
(,Clontech |
R6002 |
T6981 |
T6977 |
appos |
Clontech,digestion |
R6003 |
T6982 |
T6981 |
punct |
",",Clontech |
R6004 |
T6983 |
T6981 |
conj |
Saint-Germain-en-Laye,Clontech |
R6005 |
T6984 |
T6983 |
punct |
",",Saint-Germain-en-Laye |
R6006 |
T6985 |
T6983 |
conj |
France,Saint-Germain-en-Laye |
R6007 |
T6986 |
T6981 |
punct |
),Clontech |
R6008 |
T6987 |
T6988 |
auxpass |
was,digested |
R6009 |
T6988 |
T6972 |
advcl |
digested,excised |
R601 |
T715 |
T715 |
ROOT |
account,account |
R6010 |
T6989 |
T6988 |
prep |
with,digested |
R6011 |
T6990 |
T6989 |
pobj |
BamHI,with |
R6012 |
T6991 |
T6972 |
punct |
.,excised |
R6013 |
T6992 |
T6994 |
nsubjpass |
DNA,recovered |
R6014 |
T6993 |
T6994 |
auxpass |
was,recovered |
R6015 |
T6994 |
T6994 |
ROOT |
recovered,recovered |
R6016 |
T6995 |
T6994 |
agent |
by,recovered |
R6017 |
T6996 |
T6997 |
compound |
phenol,extraction |
R6018 |
T6997 |
T6995 |
pobj |
extraction,by |
R6019 |
T6998 |
T6997 |
cc |
and,extraction |
R602 |
T716 |
T715 |
prep |
for,account |
R6020 |
T6999 |
T7000 |
compound |
ethanol,precipitation |
R6021 |
T7000 |
T6997 |
conj |
precipitation,extraction |
R6022 |
T7001 |
T6994 |
punct |
",",recovered |
R6023 |
T7002 |
T6994 |
cc |
and,recovered |
R6024 |
T7003 |
T7006 |
preconj |
both,fragment |
R6025 |
T7004 |
T7006 |
det |
the,fragment |
R6026 |
T7005 |
T7006 |
compound |
GATA-3,fragment |
R6027 |
T7006 |
T7029 |
nsubjpass |
fragment,inactivated |
R6028 |
T7007 |
T7006 |
cc |
and,fragment |
R6029 |
T7008 |
T7010 |
det |
the,vector |
R603 |
T579 |
T577 |
dobj |
translocation,inhibits |
R6030 |
T7009 |
T7010 |
compound |
pEGFP-C2,vector |
R6031 |
T7010 |
T7006 |
conj |
vector,fragment |
R6032 |
T7011 |
T7006 |
acl |
blunt-ended,fragment |
R6033 |
T7012 |
T7011 |
agent |
by,blunt-ended |
R6034 |
T7013 |
T7012 |
pobj |
incubation,by |
R6035 |
T7014 |
T7011 |
prep |
with,blunt-ended |
R6036 |
T7015 |
T7014 |
pobj |
Klenow,with |
R6037 |
T7016 |
T7015 |
punct |
(,Klenow |
R6038 |
T7017 |
T7018 |
compound |
Bioline,Bio-27029 |
R6039 |
T7018 |
T7015 |
appos |
Bio-27029,Klenow |
R604 |
T717 |
T720 |
det |
the,efficacy |
R6040 |
T7019 |
T7015 |
punct |
),Klenow |
R6041 |
T7020 |
T7011 |
prep |
for,blunt-ended |
R6042 |
T7021 |
T7022 |
nummod |
30,min |
R6043 |
T7022 |
T7020 |
pobj |
min,for |
R6044 |
T7023 |
T7022 |
prep |
at,min |
R6045 |
T7024 |
T7025 |
nummod |
37,° |
R6046 |
T7025 |
T7027 |
nummod |
°,Klenow |
R6047 |
T7026 |
T7027 |
compound |
C.,Klenow |
R6048 |
T7027 |
T7023 |
pobj |
Klenow,at |
R6049 |
T7028 |
T7029 |
auxpass |
was,inactivated |
R605 |
T580 |
T579 |
prep |
of,translocation |
R6050 |
T7029 |
T6994 |
conj |
inactivated,recovered |
R6051 |
T7030 |
T7029 |
agent |
by,inactivated |
R6052 |
T7031 |
T7030 |
pobj |
incubation,by |
R6053 |
T7032 |
T7029 |
prep |
for,inactivated |
R6054 |
T7033 |
T7034 |
nummod |
10,min |
R6055 |
T7034 |
T7032 |
pobj |
min,for |
R6056 |
T7035 |
T7034 |
prep |
at,min |
R6057 |
T7036 |
T7037 |
nummod |
75,° |
R6058 |
T7037 |
T7039 |
nummod |
°,DNA |
R6059 |
T7038 |
T7039 |
compound |
C.,DNA |
R606 |
T581 |
T580 |
pobj |
GATA-3,of |
R6060 |
T7039 |
T7035 |
pobj |
DNA,at |
R6061 |
T7040 |
T7041 |
auxpass |
was,recovered |
R6062 |
T7041 |
T6994 |
conj |
recovered,recovered |
R6063 |
T7042 |
T7041 |
agent |
by,recovered |
R6064 |
T7043 |
T7044 |
compound |
phenol,extraction |
R6065 |
T7044 |
T7042 |
pobj |
extraction,by |
R6066 |
T7045 |
T7044 |
cc |
and,extraction |
R6067 |
T7046 |
T7047 |
compound |
ethanol,precipitation |
R6068 |
T7047 |
T7044 |
conj |
precipitation,extraction |
R6069 |
T7048 |
T7041 |
punct |
",",recovered |
R607 |
T582 |
T579 |
cc |
and,translocation |
R6070 |
T7049 |
T6994 |
cc |
and,recovered |
R6071 |
T7050 |
T7054 |
preconj |
both,fragment |
R6072 |
T7051 |
T7054 |
det |
the,fragment |
R6073 |
T7052 |
T7054 |
amod |
blunt-ended,fragment |
R6074 |
T7053 |
T7054 |
compound |
GATA-3,fragment |
R6075 |
T7054 |
T7061 |
nsubjpass |
fragment,digested |
R6076 |
T7055 |
T7054 |
cc |
and,fragment |
R6077 |
T7056 |
T7058 |
det |
the,vector |
R6078 |
T7057 |
T7058 |
compound |
GFP,vector |
R6079 |
T7058 |
T7054 |
conj |
vector,fragment |
R608 |
T583 |
T579 |
conj |
expression,translocation |
R6080 |
T7059 |
T7061 |
auxpass |
were,digested |
R6081 |
T7060 |
T7061 |
advmod |
subsequently,digested |
R6082 |
T7061 |
T6994 |
conj |
digested,recovered |
R6083 |
T7062 |
T7061 |
prep |
with,digested |
R6084 |
T7063 |
T7062 |
pobj |
EcoRI,with |
R6085 |
T7064 |
T7061 |
prep |
before,digested |
R6086 |
T7065 |
T7070 |
det |
the,′ |
R6087 |
T7066 |
T7070 |
nummod |
5,′ |
R6088 |
T7067 |
T7069 |
punct |
′,EcoRI/3 |
R6089 |
T7068 |
T7069 |
punct |
-,EcoRI/3 |
R609 |
T584 |
T583 |
prep |
of,expression |
R6090 |
T7069 |
T7070 |
compound |
EcoRI/3,′ |
R6091 |
T7070 |
T7064 |
pobj |
′,before |
R6092 |
T7071 |
T7074 |
amod |
blunt,fragment |
R6093 |
T7072 |
T7074 |
compound |
end,fragment |
R6094 |
T7073 |
T7074 |
compound |
GATA-3,fragment |
R6095 |
T7074 |
T7076 |
nsubjpass |
fragment,inserted |
R6096 |
T7075 |
T7076 |
auxpass |
was,inserted |
R6097 |
T7076 |
T6994 |
conj |
inserted,recovered |
R6098 |
T7077 |
T7076 |
prep |
into,inserted |
R6099 |
T7078 |
T7083 |
det |
the,′ |
R610 |
T585 |
T586 |
amod |
Th2,cytokines |
R6100 |
T7079 |
T7082 |
nummod |
5,EcoRI/3 |
R6101 |
T7080 |
T7082 |
punct |
′,EcoRI/3 |
R6102 |
T7081 |
T7082 |
punct |
-,EcoRI/3 |
R6103 |
T7082 |
T7083 |
compound |
EcoRI/3,′ |
R6104 |
T7083 |
T7077 |
pobj |
′,into |
R6105 |
T7084 |
T7085 |
nsubj |
blunt,ended |
R6106 |
T7085 |
T7076 |
advcl |
ended,inserted |
R6107 |
T7086 |
T7087 |
compound |
GFP,vector |
R6108 |
T7087 |
T7085 |
dobj |
vector,ended |
R6109 |
T7088 |
T7085 |
punct |
.,ended |
R611 |
T586 |
T584 |
pobj |
cytokines,of |
R6110 |
T7089 |
T7090 |
amod |
Positive,clones |
R6111 |
T7090 |
T7092 |
nsubjpass |
clones,confirmed |
R6112 |
T7091 |
T7092 |
auxpass |
were,confirmed |
R6113 |
T7092 |
T7092 |
ROOT |
confirmed,confirmed |
R6114 |
T7093 |
T7092 |
agent |
by,confirmed |
R6115 |
T7094 |
T7093 |
pobj |
digestion,by |
R6116 |
T7095 |
T7094 |
cc |
and,digestion |
R6117 |
T7096 |
T7094 |
conj |
size,digestion |
R6118 |
T7097 |
T7094 |
conj |
analysis,digestion |
R6119 |
T7098 |
T7092 |
prep |
by,confirmed |
R612 |
T718 |
T720 |
amod |
striking,efficacy |
R6120 |
T7099 |
T7100 |
nummod |
1,% |
R6121 |
T7100 |
T7103 |
compound |
%,electrophoresis |
R6122 |
T7101 |
T7102 |
amod |
agarose,gel |
R6123 |
T7102 |
T7103 |
compound |
gel,electrophoresis |
R6124 |
T7103 |
T7098 |
pobj |
electrophoresis,by |
R6125 |
T7104 |
T7098 |
cc |
and,by |
R6126 |
T7105 |
T7098 |
conj |
by,by |
R6127 |
T7106 |
T7105 |
pcomp |
sequencing,by |
R6128 |
T7107 |
T7092 |
punct |
.,confirmed |
R613 |
T587 |
T577 |
prep |
via,inhibits |
R614 |
T719 |
T720 |
amod |
clinical,efficacy |
R615 |
T720 |
T716 |
pobj |
efficacy,for |
R616 |
T588 |
T589 |
det |
a,mechanism |
R617 |
T721 |
T720 |
prep |
of,efficacy |
R618 |
T722 |
T721 |
pobj |
corticosteroids,of |
R619 |
T589 |
T587 |
pobj |
mechanism,via |
R620 |
T723 |
T722 |
prep |
in,corticosteroids |
R6207 |
T7254 |
T7255 |
compound |
Transfection,HuT-78 |
R6208 |
T7255 |
T7256 |
compound |
HuT-78,cells |
R6209 |
T7256 |
T7258 |
nsubjpass |
cells,transfected |
R621 |
T724 |
T725 |
det |
the,treatment |
R6210 |
T7257 |
T7258 |
auxpass |
were,transfected |
R6211 |
T7258 |
T7258 |
ROOT |
transfected,transfected |
R6212 |
T7259 |
T7258 |
prep |
with,transfected |
R6213 |
T7260 |
T7261 |
det |
either,EP8 |
R6214 |
T7261 |
T7259 |
pobj |
EP8,with |
R6215 |
T7262 |
T7261 |
cc |
or,EP8 |
R6216 |
T7263 |
T7264 |
compound |
GFP,vector |
R6217 |
T7264 |
T7261 |
conj |
vector,EP8 |
R6218 |
T7265 |
T7266 |
advmod |
only,DNA |
R6219 |
T7266 |
T7267 |
nsubj |
DNA,using |
R622 |
T725 |
T723 |
pobj |
treatment,in |
R6220 |
T7267 |
T7258 |
advcl |
using,transfected |
R6221 |
T7268 |
T7269 |
compound |
solution,R |
R6222 |
T7269 |
T7267 |
dobj |
R,using |
R6223 |
T7270 |
T7269 |
punct |
",",R |
R6224 |
T7271 |
T7272 |
compound |
programme,V-001 |
R6225 |
T7272 |
T7269 |
appos |
V-001,R |
R6226 |
T7273 |
T7267 |
prep |
at,using |
R6227 |
T7274 |
T7275 |
det |
a,ratio |
R6228 |
T7275 |
T7282 |
nmod |
ratio,DNA |
R6229 |
T7276 |
T7275 |
prep |
of,ratio |
R6230 |
T7277 |
T7280 |
nummod |
3,cells/4 |
R6231 |
T7278 |
T7280 |
nummod |
×,cells/4 |
R6232 |
T7279 |
T7280 |
nummod |
106,cells/4 |
R6233 |
T7280 |
T7276 |
pobj |
cells/4,of |
R6234 |
T7281 |
T7282 |
compound |
µg,DNA |
R6235 |
T7282 |
T7273 |
pobj |
DNA,at |
R6236 |
T7283 |
T7267 |
prep |
for,using |
R6237 |
T7284 |
T7283 |
pobj |
7,for |
R6238 |
T7285 |
T7286 |
nummod |
8,h |
R6239 |
T7286 |
T7284 |
appos |
h,7 |
R624 |
T726 |
T725 |
prep |
of,treatment |
R6240 |
T7287 |
T7286 |
prep |
in,h |
R6241 |
T7288 |
T7289 |
amod |
complete,medium |
R6242 |
T7289 |
T7287 |
pobj |
medium,in |
R6243 |
T7290 |
T7286 |
punct |
(,h |
R6244 |
T7291 |
T7292 |
nummod |
10,% |
R6245 |
T7292 |
T7294 |
nmod |
%,serum |
R6246 |
T7293 |
T7294 |
amod |
bovine,serum |
R6247 |
T7294 |
T7286 |
appos |
serum,h |
R6248 |
T7295 |
T7294 |
prep |
in,serum |
R6249 |
T7296 |
T7295 |
pobj |
RPMI1640,in |
R625 |
T727 |
T728 |
amod |
allergic,diseases |
R6250 |
T7297 |
T7298 |
nummod |
+15,L-glutamine |
R6251 |
T7298 |
T7294 |
appos |
L-glutamine,serum |
R6252 |
T7299 |
T7286 |
punct |
),h |
R6253 |
T7300 |
T7258 |
prep |
according,transfected |
R6254 |
T7301 |
T7300 |
prep |
to,according |
R6255 |
T7302 |
T7305 |
det |
the,protocol |
R6256 |
T7303 |
T7305 |
amod |
general,protocol |
R6257 |
T7304 |
T7305 |
compound |
Amaxa,protocol |
R6258 |
T7305 |
T7301 |
pobj |
protocol,to |
R6259 |
T7306 |
T7305 |
prep |
for,protocol |
R626 |
T728 |
T726 |
pobj |
diseases,of |
R6260 |
T7307 |
T7306 |
pobj |
nucleofection,for |
R6261 |
T7308 |
T7258 |
punct |
.,transfected |
R6262 |
T7309 |
T7310 |
det |
The,medium |
R6263 |
T7310 |
T7313 |
nsubjpass |
medium,changed |
R6264 |
T7311 |
T7313 |
auxpass |
was,changed |
R6265 |
T7312 |
T7313 |
advmod |
subsequently,changed |
R6266 |
T7313 |
T7313 |
ROOT |
changed,changed |
R6267 |
T7314 |
T7313 |
prep |
to,changed |
R6268 |
T7315 |
T7317 |
nummod |
1,RPMI |
R6269 |
T7316 |
T7315 |
quantmod |
%,1 |
R627 |
T729 |
T715 |
punct |
.,account |
R6270 |
T7317 |
T7314 |
pobj |
RPMI,to |
R6271 |
T7318 |
T7313 |
prep |
for,changed |
R6272 |
T7319 |
T7320 |
nummod |
24,h |
R6273 |
T7320 |
T7318 |
pobj |
h,for |
R6274 |
T7321 |
T7325 |
mark |
before,added |
R6275 |
T7322 |
T7323 |
amod |
transfected,cells |
R6276 |
T7323 |
T7325 |
nsubjpass |
cells,added |
R6277 |
T7324 |
T7325 |
auxpass |
were,added |
R6278 |
T7325 |
T7313 |
advcl |
added,changed |
R6279 |
T7326 |
T7325 |
prep |
to,added |
R628 |
T730 |
T731 |
intj |
Please,see |
R6280 |
T7327 |
T7336 |
amod |
anti-CD3,performed |
R6281 |
T7328 |
T7331 |
nummod |
/,wells |
R6282 |
T7329 |
T7331 |
nummod |
CD28,wells |
R6283 |
T7330 |
T7331 |
amod |
treated,wells |
R6284 |
T7331 |
T7327 |
dobj |
wells,anti-CD3 |
R6285 |
T7332 |
T7327 |
cc |
and,anti-CD3 |
R6286 |
T7333 |
T7335 |
amod |
live,videomicroscopy |
R6287 |
T7334 |
T7335 |
compound |
cell,videomicroscopy |
R6288 |
T7335 |
T7327 |
conj |
videomicroscopy,anti-CD3 |
R6289 |
T7336 |
T7326 |
pobj |
performed,to |
R629 |
T731 |
T731 |
ROOT |
see,see |
R6290 |
T7337 |
T7313 |
punct |
.,changed |
R630 |
T732 |
T731 |
advmod |
later,see |
R631 |
T733 |
T732 |
prep |
in,later |
R633 |
T734 |
T735 |
det |
the,article |
R634 |
T735 |
T733 |
pobj |
article,in |
R635 |
T736 |
T735 |
prep |
for,article |
R636 |
T737 |
T739 |
poss |
Editors,Summary |
R638 |
T738 |
T737 |
case |
',Editors |
R639 |
T739 |
T736 |
pobj |
Summary,for |
R6411 |
T7473 |
T7476 |
compound |
Time-Lapse,cells |
R6412 |
T7474 |
T7475 |
compound |
Microscopy,HuT-78 |
R6413 |
T7475 |
T7476 |
compound |
HuT-78,cells |
R6414 |
T7476 |
T7480 |
nsubjpass |
cells,maintained |
R6415 |
T7477 |
T7476 |
acl |
expressing,cells |
R6416 |
T7478 |
T7477 |
dobj |
GATA-3-GFP,expressing |
R6417 |
T7479 |
T7480 |
auxpass |
were,maintained |
R6418 |
T7480 |
T7480 |
ROOT |
maintained,maintained |
R6419 |
T7481 |
T7480 |
prep |
at,maintained |
R6420 |
T7482 |
T7483 |
nummod |
37,° |
R6421 |
T7483 |
T7484 |
nummod |
°,C |
R6422 |
T7484 |
T7481 |
pobj |
C,at |
R6423 |
T7485 |
T7484 |
prep |
in,C |
R6424 |
T7486 |
T7487 |
compound |
growth,medium |
R6425 |
T7487 |
T7485 |
pobj |
medium,in |
R6426 |
T7488 |
T7480 |
prep |
in,maintained |
R6427 |
T7489 |
T7493 |
det |
a,chamber |
R6428 |
T7490 |
T7493 |
amod |
closed,chamber |
R6429 |
T7491 |
T7493 |
nummod |
FCS2,chamber |
R6430 |
T7492 |
T7493 |
compound |
perfusion,chamber |
R6431 |
T7493 |
T7488 |
pobj |
chamber,in |
R6432 |
T7494 |
T7495 |
punct |
(,Bioptechs |
R6433 |
T7495 |
T7493 |
appos |
Bioptechs,chamber |
R6434 |
T7496 |
T7495 |
punct |
",",Bioptechs |
R6435 |
T7497 |
T7495 |
conj |
Butler,Bioptechs |
R6436 |
T7498 |
T7497 |
punct |
",",Butler |
R6437 |
T7499 |
T7497 |
conj |
Pennsylvania,Butler |
R6438 |
T7500 |
T7499 |
punct |
",",Pennsylvania |
R6439 |
T7501 |
T7499 |
conj |
USA,Pennsylvania |
R6440 |
T7502 |
T7480 |
punct |
),maintained |
R6441 |
T7503 |
T7480 |
conj |
combined,maintained |
R6442 |
T7504 |
T7503 |
prep |
with,combined |
R6443 |
T7505 |
T7507 |
det |
an,heater |
R6444 |
T7506 |
T7507 |
amod |
objective,heater |
R6445 |
T7507 |
T7504 |
pobj |
heater,with |
R6446 |
T7508 |
T7507 |
punct |
(,heater |
R6447 |
T7509 |
T7507 |
appos |
Bioptechs,heater |
R6448 |
T7510 |
T7507 |
punct |
),heater |
R6449 |
T7511 |
T7503 |
prep |
on,combined |
R6450 |
T7512 |
T7513 |
det |
the,stage |
R6451 |
T7513 |
T7511 |
pobj |
stage,on |
R6452 |
T7514 |
T7518 |
det |
a,microscope |
R6453 |
T7515 |
T7516 |
compound |
Zeiss,Axiovert |
R6454 |
T7516 |
T7518 |
nmod |
Axiovert,microscope |
R6455 |
T7517 |
T7518 |
nummod |
200,microscope |
R6456 |
T7518 |
T7503 |
npadvmod |
microscope,combined |
R6457 |
T7519 |
T7520 |
punct |
(,Thornwood |
R6458 |
T7520 |
T7518 |
appos |
Thornwood,microscope |
R6459 |
T7521 |
T7520 |
punct |
",",Thornwood |
R6460 |
T7522 |
T7523 |
compound |
New,York |
R6461 |
T7523 |
T7520 |
npadvmod |
York,Thornwood |
R6462 |
T7524 |
T7523 |
punct |
",",York |
R6463 |
T7525 |
T7520 |
appos |
USA,Thornwood |
R6464 |
T7526 |
T7520 |
punct |
),Thornwood |
R6465 |
T7527 |
T7480 |
punct |
.,maintained |
R6466 |
T7528 |
T7530 |
nsubjpass |
Observations,made |
R6467 |
T7529 |
T7530 |
auxpass |
were,made |
R6468 |
T7530 |
T7530 |
ROOT |
made,made |
R6469 |
T7531 |
T7530 |
agent |
by,made |
R6470 |
T7532 |
T7534 |
nummod |
40,1.0 |
R6471 |
T7533 |
T7534 |
nummod |
×,1.0 |
R6472 |
T7534 |
T7531 |
pobj |
1.0,by |
R6473 |
T7535 |
T7538 |
nmod |
NA,lens |
R6474 |
T7536 |
T7538 |
amod |
oil-immersion,lens |
R6475 |
T7537 |
T7538 |
amod |
objective,lens |
R6476 |
T7538 |
T7545 |
nmod |
lens,images |
R6477 |
T7539 |
T7538 |
punct |
",",lens |
R6478 |
T7540 |
T7538 |
cc |
and,lens |
R6479 |
T7541 |
T7538 |
conj |
fluorescence,lens |
R6480 |
T7542 |
T7541 |
cc |
and,fluorescence |
R6481 |
T7543 |
T7541 |
conj |
phase,fluorescence |
R6482 |
T7544 |
T7545 |
compound |
contrast,images |
R6483 |
T7545 |
T7547 |
nsubjpass |
images,gathered |
R6484 |
T7546 |
T7547 |
auxpass |
were,gathered |
R6485 |
T7547 |
T7530 |
conj |
gathered,made |
R6486 |
T7548 |
T7547 |
advcl |
using,gathered |
R6487 |
T7549 |
T7551 |
det |
a,ORCA-ER |
R6488 |
T7550 |
T7551 |
compound |
Hamamatsu,ORCA-ER |
R6489 |
T7551 |
T7548 |
dobj |
ORCA-ER,using |
R6490 |
T7552 |
T7547 |
conj |
charged,gathered |
R6491 |
T7553 |
T7555 |
amod |
coupled,camera |
R6492 |
T7554 |
T7555 |
compound |
device,camera |
R6493 |
T7555 |
T7552 |
dobj |
camera,charged |
R6494 |
T7556 |
T7564 |
punct |
(,driven |
R6495 |
T7557 |
T7564 |
dep |
Bridgewater,driven |
R6496 |
T7558 |
T7557 |
punct |
",",Bridgewater |
R6497 |
T7559 |
T7560 |
compound |
New,Jersey |
R6498 |
T7560 |
T7557 |
conj |
Jersey,Bridgewater |
R6499 |
T7561 |
T7560 |
punct |
",",Jersey |
R6500 |
T7562 |
T7560 |
conj |
USA,Jersey |
R6501 |
T7563 |
T7564 |
punct |
),driven |
R6502 |
T7564 |
T7552 |
advcl |
driven,charged |
R6503 |
T7565 |
T7564 |
agent |
by,driven |
R6504 |
T7566 |
T7567 |
compound |
Openlab,software |
R6505 |
T7567 |
T7565 |
pobj |
software,by |
R6506 |
T7568 |
T7569 |
punct |
(,Improvision |
R6507 |
T7569 |
T7567 |
appos |
Improvision,software |
R6508 |
T7570 |
T7569 |
punct |
",",Improvision |
R6509 |
T7571 |
T7569 |
npadvmod |
Coventry,Improvision |
R6510 |
T7572 |
T7571 |
punct |
",",Coventry |
R6511 |
T7573 |
T7571 |
appos |
UK,Coventry |
R6512 |
T7574 |
T7571 |
punct |
),Coventry |
R6513 |
T7575 |
T7547 |
punct |
.,gathered |
R6514 |
T7576 |
T7578 |
nsubjpass |
Photographs,taken |
R6515 |
T7577 |
T7578 |
auxpass |
were,taken |
R6516 |
T7578 |
T7578 |
ROOT |
taken,taken |
R6517 |
T7579 |
T7578 |
prep |
at,taken |
R6518 |
T7580 |
T7579 |
pobj |
0,at |
R6519 |
T7581 |
T7580 |
punct |
",",0 |
R6520 |
T7582 |
T7580 |
appos |
30,0 |
R6521 |
T7583 |
T7580 |
punct |
",",0 |
R6522 |
T7584 |
T7580 |
appos |
60,0 |
R6523 |
T7585 |
T7584 |
punct |
",",60 |
R6524 |
T7586 |
T7584 |
conj |
120,60 |
R6525 |
T7587 |
T7578 |
punct |
",",taken |
R6526 |
T7588 |
T7578 |
cc |
and,taken |
R6527 |
T7589 |
T7590 |
nummod |
240,min |
R6528 |
T7590 |
T7578 |
conj |
min,taken |
R6529 |
T7591 |
T7578 |
punct |
.,taken |
R6614 |
T7691 |
T7693 |
compound |
Densitometric,Densitometry |
R6615 |
T7692 |
T7693 |
compound |
Analysis,Densitometry |
R6616 |
T7693 |
T7698 |
nsubjpass |
Densitometry,performed |
R6617 |
T7694 |
T7693 |
prep |
of,Densitometry |
R6618 |
T7695 |
T7696 |
compound |
ECL,immunoblots |
R6619 |
T7696 |
T7694 |
pobj |
immunoblots,of |
R6620 |
T7697 |
T7698 |
auxpass |
was,performed |
R6621 |
T7698 |
T7698 |
ROOT |
performed,performed |
R6622 |
T7699 |
T7698 |
advcl |
using,performed |
R6623 |
T7700 |
T7703 |
nmod |
Gelworks,software |
R6624 |
T7701 |
T7703 |
nmod |
ID,software |
R6625 |
T7702 |
T7703 |
amod |
intermediate,software |
R6626 |
T7703 |
T7699 |
dobj |
software,using |
R6627 |
T7704 |
T7706 |
punct |
(,Products |
R6628 |
T7705 |
T7706 |
compound |
Ultraviolet,Products |
R6629 |
T7706 |
T7703 |
appos |
Products,software |
R6630 |
T7707 |
T7706 |
punct |
",",Products |
R6631 |
T7708 |
T7706 |
conj |
Cambridgeshire,Products |
R6632 |
T7709 |
T7708 |
punct |
",",Cambridgeshire |
R6633 |
T7710 |
T7708 |
appos |
UK,Cambridgeshire |
R6634 |
T7711 |
T7708 |
punct |
),Cambridgeshire |
R6635 |
T7712 |
T7698 |
punct |
.,performed |
R6636 |
T7713 |
T7717 |
advmod |
Briefly,scanned |
R6637 |
T7714 |
T7717 |
punct |
",",scanned |
R6638 |
T7715 |
T7717 |
nsubjpass |
immunoblots,scanned |
R6639 |
T7716 |
T7717 |
auxpass |
were,scanned |
R6640 |
T7717 |
T7717 |
ROOT |
scanned,scanned |
R6641 |
T7718 |
T7717 |
cc |
and,scanned |
R6642 |
T7719 |
T7721 |
nsubjpass |
gates,drawn |
R6643 |
T7720 |
T7721 |
auxpass |
were,drawn |
R6644 |
T7721 |
T7717 |
conj |
drawn,scanned |
R6645 |
T7722 |
T7721 |
advmod |
tightly,drawn |
R6646 |
T7723 |
T7721 |
prep |
around,drawn |
R6647 |
T7724 |
T7725 |
det |
each,band |
R6648 |
T7725 |
T7723 |
pobj |
band,around |
R6649 |
T7726 |
T7721 |
punct |
.,drawn |
R6650 |
T7727 |
T7728 |
compound |
Background,values |
R6651 |
T7728 |
T7733 |
nsubjpass |
values,subtracted |
R6652 |
T7729 |
T7728 |
prep |
from,values |
R6653 |
T7730 |
T7731 |
det |
each,lane |
R6654 |
T7731 |
T7729 |
pobj |
lane,from |
R6655 |
T7732 |
T7733 |
auxpass |
were,subtracted |
R6656 |
T7733 |
T7733 |
ROOT |
subtracted,subtracted |
R6657 |
T7734 |
T7735 |
aux |
to,normalize |
R6658 |
T7735 |
T7733 |
xcomp |
normalize,subtracted |
R6659 |
T7736 |
T7737 |
det |
each,measurement |
R6660 |
T7737 |
T7735 |
dobj |
measurement,normalize |
R6661 |
T7738 |
T7733 |
punct |
.,subtracted |
R6662 |
T7739 |
T7740 |
det |
The,bands |
R6663 |
T7740 |
T7742 |
nsubjpass |
bands,quantified |
R6664 |
T7741 |
T7742 |
auxpass |
were,quantified |
R6665 |
T7742 |
T7742 |
ROOT |
quantified,quantified |
R6666 |
T7743 |
T7742 |
advcl |
using,quantified |
R6667 |
T7744 |
T7746 |
det |
the,software |
R6668 |
T7745 |
T7746 |
compound |
Gelworks,software |
R6669 |
T7746 |
T7743 |
dobj |
software,using |
R6670 |
T7747 |
T7742 |
punct |
.,quantified |
R6671 |
T7748 |
T7750 |
det |
All,blots |
R6672 |
T7749 |
T7750 |
amod |
Western,blots |
R6673 |
T7750 |
T7752 |
nsubjpass |
blots,exposed |
R6674 |
T7751 |
T7752 |
auxpass |
were,exposed |
R6675 |
T7752 |
T7752 |
ROOT |
exposed,exposed |
R6676 |
T7753 |
T7752 |
prep |
to,exposed |
R6677 |
T7754 |
T7753 |
pobj |
film,to |
R6678 |
T7755 |
T7754 |
prep |
for,film |
R6679 |
T7756 |
T7757 |
amod |
varying,lengths |
R6680 |
T7757 |
T7755 |
pobj |
lengths,for |
R6681 |
T7758 |
T7757 |
prep |
of,lengths |
R6682 |
T7759 |
T7758 |
pobj |
time,of |
R6683 |
T7760 |
T7752 |
punct |
",",exposed |
R6684 |
T7761 |
T7752 |
cc |
and,exposed |
R6685 |
T7762 |
T7763 |
advmod |
only,films |
R6686 |
T7763 |
T7770 |
nsubjpass |
films,selected |
R6687 |
T7764 |
T7763 |
acl |
generating,films |
R6688 |
T7765 |
T7766 |
amod |
subsaturating,levels |
R6689 |
T7766 |
T7764 |
dobj |
levels,generating |
R6690 |
T7767 |
T7766 |
prep |
of,levels |
R6691 |
T7768 |
T7767 |
pobj |
intensity,of |
R6692 |
T7769 |
T7770 |
auxpass |
were,selected |
R6693 |
T7770 |
T7752 |
conj |
selected,exposed |
R6694 |
T7771 |
T7770 |
prep |
for,selected |
R6695 |
T7772 |
T7773 |
amod |
densitometric,evaluation |
R6696 |
T7773 |
T7771 |
pobj |
evaluation,for |
R6697 |
T7774 |
T7770 |
punct |
.,selected |
R6852 |
T7934 |
T7935 |
compound |
Statistical,Analysis |
R6853 |
T7935 |
T7936 |
compound |
Analysis,Data |
R6854 |
T7936 |
T7944 |
nsubjpass |
Data,presented |
R6855 |
T7937 |
T7936 |
prep |
from,Data |
R6856 |
T7938 |
T7942 |
nummod |
three,experiments |
R6857 |
T7939 |
T7938 |
cc |
or,three |
R6858 |
T7940 |
T7938 |
conj |
more,three |
R6859 |
T7941 |
T7942 |
amod |
independent,experiments |
R6860 |
T7942 |
T7937 |
pobj |
experiments,from |
R6861 |
T7943 |
T7944 |
auxpass |
are,presented |
R6862 |
T7944 |
T7944 |
ROOT |
presented,presented |
R6863 |
T7945 |
T7944 |
prep |
as,presented |
R6864 |
T7946 |
T7950 |
det |
the,error |
R6865 |
T7947 |
T7950 |
amod |
mean,error |
R6866 |
T7948 |
T7950 |
compound |
±,error |
R6867 |
T7949 |
T7950 |
compound |
standard,error |
R6868 |
T7950 |
T7945 |
pobj |
error,as |
R6869 |
T7951 |
T7950 |
prep |
of,error |
R6870 |
T7952 |
T7953 |
det |
the,mean |
R6871 |
T7953 |
T7951 |
pobj |
mean,of |
R6872 |
T7954 |
T7955 |
punct |
(,SEM |
R6873 |
T7955 |
T7953 |
appos |
SEM,mean |
R6874 |
T7956 |
T7955 |
punct |
),SEM |
R6875 |
T7957 |
T7950 |
punct |
",",error |
R6876 |
T7958 |
T7950 |
prep |
except,error |
R6877 |
T7959 |
T7960 |
advmod |
where,stated |
R6878 |
T7960 |
T7958 |
pcomp |
stated,except |
R6879 |
T7961 |
T7944 |
cc |
and,presented |
R6880 |
T7962 |
T7963 |
auxpass |
were,compared |
R6881 |
T7963 |
T7944 |
conj |
compared,presented |
R6882 |
T7964 |
T7963 |
advcl |
using,compared |
R6883 |
T7965 |
T7966 |
compound |
GraphPad,Prism |
R6884 |
T7966 |
T7964 |
dobj |
Prism,using |
R6885 |
T7967 |
T7966 |
nummod |
4,Prism |
R6886 |
T7968 |
T7970 |
punct |
(,Software |
R6887 |
T7969 |
T7970 |
compound |
GraphPad,Software |
R6888 |
T7970 |
T7966 |
conj |
Software,Prism |
R6889 |
T7971 |
T7970 |
punct |
",",Software |
R6890 |
T7972 |
T7970 |
appos |
http://www.graphpad.com,Software |
R6891 |
T7973 |
T7970 |
punct |
),Software |
R6892 |
T7974 |
T7944 |
punct |
.,presented |
R6893 |
T7975 |
T7976 |
nsubj |
Results,were |
R6894 |
T7976 |
T7976 |
ROOT |
were,were |
R6895 |
T7977 |
T7976 |
acomp |
analysed,were |
R6896 |
T7978 |
T7976 |
advcl |
using,were |
R6897 |
T7979 |
T7980 |
amod |
one-way,ANOVA |
R6898 |
T7980 |
T7978 |
dobj |
ANOVA,using |
R6899 |
T7981 |
T7978 |
prep |
with,using |
R6900 |
T7982 |
T7984 |
compound |
Newman-Keuls,test |
R6901 |
T7983 |
T7984 |
compound |
post,test |
R6902 |
T7984 |
T7981 |
pobj |
test,with |
R6903 |
T7985 |
T7978 |
prep |
except,using |
R6904 |
T7986 |
T7985 |
prep |
for,except |
R6905 |
T7987 |
T7988 |
det |
the,data |
R6906 |
T7988 |
T7986 |
pobj |
data,for |
R6907 |
T7989 |
T7988 |
prep |
from,data |
R6908 |
T7990 |
T7995 |
det |
the,study |
R6909 |
T7991 |
T7993 |
prep |
in,inhaled |
R6910 |
T7992 |
T7991 |
pobj |
vivo,in |
R6911 |
T7993 |
T7995 |
amod |
inhaled,study |
R6912 |
T7994 |
T7995 |
compound |
FP,study |
R6913 |
T7995 |
T7989 |
pobj |
study,from |
R6914 |
T7996 |
T7995 |
punct |
",",study |
R6915 |
T7997 |
T7999 |
nsubjpass |
which,analysed |
R6916 |
T7998 |
T7999 |
auxpass |
was,analysed |
R6917 |
T7999 |
T7995 |
relcl |
analysed,study |
R6918 |
T8000 |
T7999 |
agent |
by,analysed |
R6919 |
T8001 |
T8003 |
poss |
Friedman,test |
R6920 |
T8002 |
T8001 |
case |
's,Friedman |
R6921 |
T8003 |
T8000 |
pobj |
test,by |
R6922 |
T8004 |
T8003 |
prep |
with,test |
R6923 |
T8005 |
T8006 |
amod |
subsequent,Wilcoxson |
R6924 |
T8006 |
T8004 |
pobj |
Wilcoxson,with |
R6925 |
T8007 |
T8008 |
amod |
matched,pair |
R6926 |
T8008 |
T8009 |
nsubj |
pair,signed |
R6927 |
T8009 |
T7976 |
conj |
signed,were |
R6928 |
T8010 |
T8012 |
compound |
rank,test |
R6929 |
T8011 |
T8012 |
compound |
sum,test |
R6930 |
T8012 |
T8009 |
dobj |
test,signed |
R6931 |
T8013 |
T8009 |
punct |
.,signed |
R6932 |
T8014 |
T8019 |
nsubjpass |
Data,presented |
R6933 |
T8015 |
T8014 |
prep |
from,Data |
R6934 |
T8016 |
T8017 |
det |
this,analysis |
R6935 |
T8017 |
T8015 |
pobj |
analysis,from |
R6936 |
T8018 |
T8019 |
auxpass |
are,presented |
R6937 |
T8019 |
T8019 |
ROOT |
presented,presented |
R6938 |
T8020 |
T8019 |
prep |
as,presented |
R6939 |
T8021 |
T8023 |
det |
a,plot |
R6940 |
T8022 |
T8023 |
compound |
box-and-whiskers,plot |
R6941 |
T8023 |
T8020 |
pobj |
plot,as |
R6942 |
T8024 |
T8019 |
punct |
.,presented |
R6943 |
T8025 |
T8027 |
poss |
Friedman,test |
R6944 |
T8026 |
T8025 |
case |
's,Friedman |
R6945 |
T8027 |
T8029 |
nsubjpass |
test,used |
R6946 |
T8028 |
T8029 |
auxpass |
was,used |
R6947 |
T8029 |
T8029 |
ROOT |
used,used |
R6948 |
T8030 |
T8035 |
mark |
as,obtained |
R6949 |
T8031 |
T8033 |
nummod |
three,measures |
R6950 |
T8032 |
T8033 |
amod |
matched,measures |
R6951 |
T8033 |
T8035 |
nsubjpass |
measures,obtained |
R6952 |
T8034 |
T8035 |
auxpass |
were,obtained |
R6953 |
T8035 |
T8029 |
advcl |
obtained,used |
R6954 |
T8036 |
T8035 |
advcl |
using,obtained |
R6955 |
T8037 |
T8036 |
dobj |
placebo,using |
R6956 |
T8038 |
T8037 |
punct |
",",placebo |
R6957 |
T8039 |
T8040 |
nummod |
100,µg |
R6958 |
T8040 |
T8037 |
conj |
µg,placebo |
R6959 |
T8041 |
T8040 |
punct |
",",µg |
R6960 |
T8042 |
T8040 |
cc |
and,µg |
R6961 |
T8043 |
T8044 |
nummod |
500,µg |
R6962 |
T8044 |
T8040 |
conj |
µg,µg |
R6963 |
T8045 |
T8044 |
prep |
of,µg |
R6964 |
T8046 |
T8047 |
amod |
inhaled,FP |
R6965 |
T8047 |
T8045 |
pobj |
FP,of |
R6966 |
T8048 |
T8047 |
punct |
",",FP |
R6967 |
T8049 |
T8050 |
nsubj |
which,had |
R6968 |
T8050 |
T8047 |
relcl |
had,FP |
R6969 |
T8051 |
T8053 |
amod |
variable,levels |
R6970 |
T8052 |
T8053 |
compound |
baseline,levels |
R6971 |
T8053 |
T8050 |
dobj |
levels,had |
R6972 |
T8054 |
T8029 |
punct |
.,used |
R6973 |
T8055 |
T8058 |
nsubj |
We,assume |
R6974 |
T8056 |
T8058 |
aux |
did,assume |
R6975 |
T8057 |
T8058 |
neg |
not,assume |
R6976 |
T8058 |
T8058 |
ROOT |
assume,assume |
R6977 |
T8059 |
T8061 |
det |
a,distribution |
R6978 |
T8060 |
T8061 |
amod |
Gaussian,distribution |
R6979 |
T8061 |
T8058 |
dobj |
distribution,assume |
R6980 |
T8062 |
T8061 |
prep |
of,distribution |
R6981 |
T8063 |
T8064 |
det |
the,data |
R6982 |
T8064 |
T8062 |
pobj |
data,of |
R6983 |
T8065 |
T8061 |
amod |
due,distribution |
R6984 |
T8066 |
T8065 |
pcomp |
to,due |
R6985 |
T8067 |
T8069 |
det |
the,numbers |
R6986 |
T8068 |
T8069 |
amod |
limited,numbers |
R6987 |
T8069 |
T8065 |
pobj |
numbers,due |
R6988 |
T8070 |
T8069 |
prep |
of,numbers |
R6989 |
T8071 |
T8070 |
pobj |
participants,of |
R6990 |
T8072 |
T8071 |
acl |
analysed,participants |
R6991 |
T8073 |
T8061 |
punct |
(,distribution |
R6992 |
T8074 |
T8061 |
appos |
seven,distribution |
R6993 |
T8075 |
T8061 |
punct |
),distribution |
R6994 |
T8076 |
T8058 |
punct |
.,assume |
R6995 |
T8077 |
T8079 |
det |
The,hypothesis |
R6996 |
T8078 |
T8079 |
amod |
null,hypothesis |
R6997 |
T8079 |
T8081 |
nsubjpass |
hypothesis,rejected |
R6998 |
T8080 |
T8081 |
auxpass |
was,rejected |
R6999 |
T8081 |
T8081 |
ROOT |
rejected,rejected |
R7000 |
T8082 |
T8081 |
prep |
at,rejected |
R7001 |
T8083 |
T8084 |
compound |
p,< |
R7002 |
T8084 |
T8085 |
compound |
<,0.05 |
R7003 |
T8085 |
T8082 |
pobj |
0.05,at |
R7004 |
T8086 |
T8081 |
punct |
.,rejected |
R7296 |
T8451 |
T8452 |
det |
The,Effect |
R7297 |
T8452 |
T8463 |
nsubj |
Effect,are |
R7298 |
T8453 |
T8452 |
prep |
of,Effect |
R7299 |
T8454 |
T8453 |
pobj |
Corticosteroids,of |
R7300 |
T8455 |
T8452 |
prep |
on,Effect |
R7301 |
T8456 |
T8458 |
compound |
GATA-3,Translocation |
R7302 |
T8457 |
T8458 |
compound |
Nuclear,Translocation |
R7303 |
T8458 |
T8455 |
pobj |
Translocation,on |
R7304 |
T8459 |
T8458 |
cc |
and,Translocation |
R7305 |
T8460 |
T8462 |
compound |
IL-4,Corticosteroids |
R7306 |
T8461 |
T8462 |
compound |
mRNA,Corticosteroids |
R7307 |
T8462 |
T8458 |
conj |
Corticosteroids,Translocation |
R7308 |
T8463 |
T8463 |
ROOT |
are,are |
R7309 |
T8464 |
T8463 |
acomp |
effective,are |
R7310 |
T8465 |
T8464 |
prep |
in,effective |
R7311 |
T8466 |
T8465 |
pcomp |
inhibiting,in |
R7312 |
T8467 |
T8470 |
amod |
GATA-3-regulated,expression |
R7313 |
T8468 |
T8469 |
compound |
IL-4,gene |
R7314 |
T8469 |
T8470 |
compound |
gene,expression |
R7315 |
T8470 |
T8466 |
dobj |
expression,inhibiting |
R7316 |
T8471 |
T8466 |
prep |
in,inhibiting |
R7317 |
T8472 |
T8471 |
pobj |
vitro,in |
R7318 |
T8473 |
T8471 |
cc |
and,in |
R7319 |
T8474 |
T8471 |
conj |
in,in |
R7320 |
T8475 |
T8474 |
pobj |
vivo,in |
R7321 |
T8476 |
T8478 |
nmod |
[,] |
R7322 |
T8477 |
T8478 |
nummod |
32,] |
R7323 |
T8478 |
T8463 |
attr |
],are |
R7324 |
T8479 |
T8463 |
punct |
.,are |
R7325 |
T8480 |
T8482 |
nsubj |
We,investigated |
R7326 |
T8481 |
T8482 |
advmod |
therefore,investigated |
R7327 |
T8482 |
T8482 |
ROOT |
investigated,investigated |
R7328 |
T8483 |
T8485 |
mark |
whether,affect |
R7329 |
T8484 |
T8485 |
nsubj |
corticosteroids,affect |
R7330 |
T8485 |
T8482 |
ccomp |
affect,investigated |
R7331 |
T8486 |
T8487 |
compound |
anti-CD3,/ |
R7332 |
T8487 |
T8485 |
dobj |
/,affect |
R7333 |
T8488 |
T8487 |
nummod |
CD28,/ |
R7334 |
T8489 |
T8482 |
dep |
stimulated,investigated |
R7335 |
T8490 |
T8491 |
amod |
nuclear,import |
R7336 |
T8491 |
T8489 |
dobj |
import,stimulated |
R7337 |
T8492 |
T8491 |
prep |
of,import |
R7338 |
T8493 |
T8492 |
pobj |
GATA-3,of |
R7339 |
T8494 |
T8482 |
punct |
.,investigated |
R7340 |
T8495 |
T8502 |
nsubj |
Stimulation,resulted |
R7341 |
T8496 |
T8495 |
prep |
of,Stimulation |
R7342 |
T8497 |
T8496 |
pobj |
cells,of |
R7343 |
T8498 |
T8497 |
prep |
with,cells |
R7344 |
T8499 |
T8500 |
compound |
anti-CD3,/ |
R7345 |
T8500 |
T8498 |
pobj |
/,with |
R7346 |
T8501 |
T8500 |
nummod |
CD28,/ |
R7347 |
T8502 |
T8502 |
ROOT |
resulted,resulted |
R7348 |
T8503 |
T8502 |
prep |
in,resulted |
R7349 |
T8504 |
T8508 |
det |
a,translocation |
R7350 |
T8505 |
T8508 |
amod |
rapid,translocation |
R7351 |
T8506 |
T8508 |
nmod |
cytoplasmic/nuclear,translocation |
R7352 |
T8507 |
T8508 |
compound |
GATA-3,translocation |
R7353 |
T8508 |
T8503 |
pobj |
translocation,in |
R7354 |
T8509 |
T8510 |
punct |
(,Figure |
R7355 |
T8510 |
T8511 |
nmod |
Figure,1A |
R7356 |
T8511 |
T8508 |
appos |
1A,translocation |
R7357 |
T8512 |
T8508 |
punct |
),translocation |
R7358 |
T8513 |
T8502 |
punct |
",",resulted |
R7359 |
T8514 |
T8502 |
advcl |
confirming,resulted |
R7360 |
T8515 |
T8517 |
poss |
our,results |
R7361 |
T8516 |
T8517 |
amod |
previous,results |
R7362 |
T8517 |
T8514 |
dobj |
results,confirming |
R7363 |
T8518 |
T8520 |
nmod |
[,] |
R7364 |
T8519 |
T8520 |
nummod |
12,] |
R7365 |
T8520 |
T8517 |
appos |
],results |
R7366 |
T8521 |
T8502 |
punct |
.,resulted |
R7367 |
T8522 |
T8524 |
nsubj |
We,confirmed |
R7368 |
T8523 |
T8524 |
advmod |
also,confirmed |
R7369 |
T8524 |
T8524 |
ROOT |
confirmed,confirmed |
R7370 |
T8525 |
T8527 |
det |
a,separation |
R7371 |
T8526 |
T8527 |
amod |
clear,separation |
R7372 |
T8527 |
T8524 |
dobj |
separation,confirmed |
R7373 |
T8528 |
T8527 |
prep |
of,separation |
R7374 |
T8529 |
T8532 |
amod |
nuclear,fractions |
R7375 |
T8530 |
T8529 |
cc |
and,nuclear |
R7376 |
T8531 |
T8529 |
conj |
cytosolic,nuclear |
R7377 |
T8532 |
T8528 |
pobj |
fractions,of |
R7378 |
T8533 |
T8534 |
mark |
as,indicated |
R7379 |
T8534 |
T8527 |
advcl |
indicated,separation |
R7380 |
T8535 |
T8534 |
agent |
by,indicated |
R7381 |
T8536 |
T8535 |
pobj |
histone,by |
R7382 |
T8537 |
T8536 |
nummod |
H1,histone |
R7383 |
T8538 |
T8536 |
cc |
and,histone |
R7384 |
T8539 |
T8540 |
nummod |
MEK-1,markers |
R7385 |
T8540 |
T8536 |
conj |
markers,histone |
R7386 |
T8541 |
T8543 |
punct |
(,1B |
R7387 |
T8542 |
T8543 |
compound |
Figure,1B |
R7388 |
T8543 |
T8540 |
appos |
1B,markers |
R7389 |
T8544 |
T8543 |
punct |
),1B |
R7390 |
T8545 |
T8524 |
punct |
.,confirmed |
R7391 |
T8546 |
T8550 |
det |
The,FP |
R7392 |
T8547 |
T8550 |
amod |
potent,FP |
R7393 |
T8548 |
T8550 |
amod |
topical,FP |
R7394 |
T8549 |
T8550 |
amod |
corticosteroid,FP |
R7395 |
T8550 |
T8551 |
nsubj |
FP,caused |
R7396 |
T8551 |
T8551 |
ROOT |
caused,caused |
R7397 |
T8552 |
T8553 |
amod |
sustained,loss |
R7398 |
T8553 |
T8551 |
dobj |
loss,caused |
R7399 |
T8554 |
T8553 |
prep |
of,loss |
R7400 |
T8555 |
T8557 |
amod |
nuclear,expression |
R7401 |
T8556 |
T8557 |
amod |
GATA-3,expression |
R7402 |
T8557 |
T8554 |
pobj |
expression,of |
R7403 |
T8558 |
T8557 |
cc |
and,expression |
R7404 |
T8559 |
T8560 |
amod |
cytoplasmic,retention |
R7405 |
T8560 |
T8557 |
conj |
retention,expression |
R7406 |
T8561 |
T8557 |
prep |
of,expression |
R7407 |
T8562 |
T8561 |
pobj |
GATA-3,of |
R7408 |
T8563 |
T8553 |
prep |
at,loss |
R7409 |
T8564 |
T8563 |
pobj |
concentrations,at |
R7410 |
T8565 |
T8564 |
acl |
ranging,concentrations |
R7411 |
T8566 |
T8565 |
prep |
from,ranging |
R7412 |
T8567 |
T8568 |
nummod |
10,− |
R7413 |
T8568 |
T8566 |
pobj |
−,from |
R7414 |
T8569 |
T8571 |
quantmod |
12,10 |
R7415 |
T8570 |
T8571 |
quantmod |
to,10 |
R7416 |
T8571 |
T8572 |
nummod |
10,− |
R7417 |
T8572 |
T8574 |
nummod |
−,M |
R7418 |
T8573 |
T8574 |
nummod |
8,M |
R7419 |
T8574 |
T8566 |
pobj |
M,from |
R7420 |
T8575 |
T8574 |
punct |
",",M |
R7421 |
T8576 |
T8577 |
nsubj |
which,cover |
R7422 |
T8577 |
T8574 |
relcl |
cover,M |
R7423 |
T8578 |
T8580 |
det |
the,range |
R7424 |
T8579 |
T8580 |
amod |
therapeutic,range |
R7425 |
T8580 |
T8577 |
dobj |
range,cover |
R7426 |
T8581 |
T8583 |
nmod |
[,] |
R7427 |
T8582 |
T8583 |
nummod |
37,] |
R7428 |
T8583 |
T8580 |
appos |
],range |
R7429 |
T8584 |
T8551 |
punct |
.,caused |
R7430 |
T8585 |
T8586 |
det |
This,effect |
R7431 |
T8586 |
T8587 |
nsubj |
effect,was |
R7432 |
T8587 |
T8587 |
ROOT |
was,was |
R7433 |
T8588 |
T8587 |
attr |
concentration,was |
R7434 |
T8589 |
T8588 |
punct |
-,concentration |
R7435 |
T8590 |
T8588 |
cc |
and,concentration |
R7436 |
T8591 |
T8588 |
conj |
time-dependent,concentration |
R7437 |
T8592 |
T8587 |
punct |
",",was |
R7438 |
T8593 |
T8587 |
prep |
with,was |
R7439 |
T8594 |
T8596 |
det |
a,effect |
R7440 |
T8595 |
T8596 |
amod |
peak,effect |
R7441 |
T8596 |
T8593 |
pobj |
effect,with |
R7442 |
T8597 |
T8596 |
prep |
of,effect |
R7443 |
T8598 |
T8597 |
pobj |
11.6-fold,of |
R7444 |
T8599 |
T8596 |
prep |
at,effect |
R7445 |
T8600 |
T8601 |
nummod |
30,min |
R7446 |
T8601 |
T8599 |
pobj |
min,at |
R7447 |
T8602 |
T8601 |
prep |
at,min |
R7448 |
T8603 |
T8604 |
det |
a,concentration |
R7449 |
T8604 |
T8602 |
pobj |
concentration,at |
R7450 |
T8605 |
T8604 |
prep |
of,concentration |
R7451 |
T8606 |
T8608 |
quantmod |
10,8 |
R7452 |
T8607 |
T8608 |
quantmod |
−,8 |
R7453 |
T8608 |
T8605 |
pobj |
8,of |
R7454 |
T8609 |
T8608 |
quantmod |
M,8 |
R7455 |
T8610 |
T8612 |
punct |
(,1C |
R7456 |
T8611 |
T8612 |
compound |
Figure,1C |
R7457 |
T8612 |
T8609 |
appos |
1C,M |
R7458 |
T8613 |
T8612 |
punct |
),1C |
R7459 |
T8614 |
T8587 |
cc |
and,was |
R7460 |
T8615 |
T8616 |
auxpass |
was,associated |
R7461 |
T8616 |
T8624 |
parataxis |
associated,stimulated |
R7462 |
T8617 |
T8616 |
prep |
with,associated |
R7463 |
T8618 |
T8619 |
amod |
marked,reductions |
R7464 |
T8619 |
T8617 |
pobj |
reductions,with |
R7465 |
T8620 |
T8619 |
prep |
in,reductions |
R7466 |
T8621 |
T8622 |
amod |
anti-CD3,/ |
R7467 |
T8622 |
T8620 |
pobj |
/,in |
R7468 |
T8623 |
T8622 |
nummod |
CD28,/ |
R7469 |
T8624 |
T8587 |
conj |
stimulated,was |
R7470 |
T8625 |
T8624 |
dobj |
IL-4,stimulated |
R7471 |
T8626 |
T8625 |
cc |
and,IL-4 |
R7472 |
T8627 |
T8625 |
conj |
IL-5,IL-4 |
R7473 |
T8628 |
T8629 |
compound |
mRNA,expression |
R7474 |
T8629 |
T8625 |
conj |
expression,IL-4 |
R7475 |
T8630 |
T8631 |
punct |
(,Figure |
R7476 |
T8631 |
T8629 |
appos |
Figure,expression |
R7477 |
T8632 |
T8631 |
nummod |
1D,Figure |
R7478 |
T8633 |
T8631 |
punct |
),Figure |
R7479 |
T8634 |
T8631 |
cc |
and,Figure |
R7480 |
T8635 |
T8636 |
det |
a,loss |
R7481 |
T8636 |
T8625 |
appos |
loss,IL-4 |
R7482 |
T8637 |
T8636 |
prep |
of,loss |
R7483 |
T8638 |
T8639 |
amod |
GATA-3,binding |
R7484 |
T8639 |
T8636 |
amod |
binding,loss |
R7485 |
T8640 |
T8639 |
prep |
to,binding |
R7486 |
T8641 |
T8644 |
det |
the,promoter |
R7487 |
T8642 |
T8644 |
amod |
native,promoter |
R7488 |
T8643 |
T8644 |
compound |
IL-5,promoter |
R7489 |
T8644 |
T8640 |
pobj |
promoter,to |
R7490 |
T8645 |
T8646 |
punct |
(,Figure |
R7491 |
T8646 |
T8644 |
appos |
Figure,promoter |
R7492 |
T8647 |
T8646 |
nummod |
1E,Figure |
R7493 |
T8648 |
T8646 |
punct |
),Figure |
R7494 |
T8649 |
T8587 |
punct |
.,was |
R779 |
T454 |
T473 |
npadvmod |
Suppression,plays |
R780 |
T455 |
T454 |
prep |
of,Suppression |
R781 |
T456 |
T458 |
compound |
GATA-3,Import |
R782 |
T457 |
T458 |
compound |
Nuclear,Import |
R783 |
T458 |
T455 |
pobj |
Import,of |
R784 |
T459 |
T458 |
cc |
and,Import |
R7848 |
T9109 |
T9110 |
compound |
Ligand-Activated,GR |
R7849 |
T9110 |
T9111 |
nsubj |
GR,Competes |
R785 |
T460 |
T458 |
conj |
Phosphorylation,Import |
R7850 |
T9111 |
T9111 |
ROOT |
Competes,Competes |
R7851 |
T9112 |
T9111 |
prep |
with,Competes |
R7852 |
T9113 |
T9112 |
pobj |
GATA-3,with |
R7853 |
T9114 |
T9113 |
prep |
for,GATA-3 |
R7854 |
T9115 |
T9114 |
pobj |
Importin-α,for |
R7855 |
T9116 |
T9117 |
nsubj |
We,confirmed |
R7856 |
T9117 |
T9111 |
ccomp |
confirmed,Competes |
R7857 |
T9118 |
T9117 |
cc |
and,confirmed |
R7858 |
T9119 |
T9117 |
conj |
extended,confirmed |
R7859 |
T9120 |
T9121 |
amod |
previous,data |
R786 |
T461 |
T454 |
punct |
:,Suppression |
R7860 |
T9121 |
T9119 |
dobj |
data,extended |
R7861 |
T9122 |
T9124 |
nmod |
[,] |
R7862 |
T9123 |
T9124 |
nummod |
20,] |
R7863 |
T9124 |
T9126 |
nsubj |
],show |
R7864 |
T9125 |
T9126 |
aux |
to,show |
R7865 |
T9126 |
T9119 |
advcl |
show,extended |
R7866 |
T9127 |
T9126 |
dobj |
that,show |
R7867 |
T9128 |
T9129 |
compound |
ligand-activated,GR |
R7868 |
T9129 |
T9127 |
nsubj |
GR,that |
R7869 |
T9130 |
T9132 |
advmod |
as,as |
R787 |
T462 |
T464 |
compound |
A,Mechanism |
R7870 |
T9131 |
T9132 |
advmod |
well,as |
R7871 |
T9132 |
T9129 |
cc |
as,GR |
R7872 |
T9133 |
T9134 |
amod |
GATA-3,uses |
R7873 |
T9134 |
T9129 |
conj |
uses,GR |
R7874 |
T9135 |
T9129 |
conj |
importin-α,GR |
R7875 |
T9136 |
T9135 |
prep |
for,importin-α |
R7876 |
T9137 |
T9145 |
poss |
its,) |
R7877 |
T9138 |
T9139 |
amod |
nuclear,import |
R7878 |
T9139 |
T9145 |
nmod |
import,) |
R7879 |
T9140 |
T9141 |
punct |
(,Figure |
R788 |
T463 |
T464 |
compound |
Novel,Mechanism |
R7880 |
T9141 |
T9145 |
nmod |
Figure,) |
R7881 |
T9142 |
T9141 |
nummod |
2A,Figure |
R7882 |
T9143 |
T9141 |
cc |
and,Figure |
R7883 |
T9144 |
T9141 |
conj |
2B,Figure |
R7884 |
T9145 |
T9135 |
punct |
),importin-α |
R7885 |
T9146 |
T9111 |
punct |
.,Competes |
R7886 |
T9147 |
T9148 |
det |
This,interaction |
R7887 |
T9148 |
T9153 |
nsubj |
interaction,was |
R7888 |
T9149 |
T9148 |
prep |
between,interaction |
R7889 |
T9150 |
T9149 |
pobj |
GR,between |
R789 |
T464 |
T454 |
appos |
Mechanism,Suppression |
R7890 |
T9151 |
T9150 |
cc |
and,GR |
R7891 |
T9152 |
T9150 |
conj |
importin-α,GR |
R7892 |
T9153 |
T9153 |
ROOT |
was,was |
R7893 |
T9154 |
T9153 |
acomp |
significant,was |
R7894 |
T9155 |
T9153 |
prep |
at,was |
R7895 |
T9156 |
T9155 |
pobj |
concentrations,at |
R7896 |
T9157 |
T9158 |
advmod |
as,low |
R7897 |
T9158 |
T9156 |
amod |
low,concentrations |
R7898 |
T9159 |
T9158 |
prep |
as,low |
R7899 |
T9160 |
T9161 |
nummod |
10,− |
R790 |
T465 |
T464 |
prep |
of,Mechanism |
R7900 |
T9161 |
T9159 |
pobj |
−,as |
R7901 |
T9162 |
T9163 |
nummod |
12,M |
R7902 |
T9163 |
T9158 |
npadvmod |
M,low |
R7903 |
T9164 |
T9153 |
cc |
and,was |
R7904 |
T9165 |
T9166 |
auxpass |
was,maximal |
R7905 |
T9166 |
T9153 |
conj |
maximal,was |
R7906 |
T9167 |
T9166 |
prep |
with,maximal |
R7907 |
T9168 |
T9170 |
quantmod |
10,8 |
R7908 |
T9169 |
T9170 |
quantmod |
−,8 |
R7909 |
T9170 |
T9167 |
pobj |
8,with |
R791 |
T466 |
T467 |
compound |
Corticosteroid,Action |
R7910 |
T9171 |
T9172 |
compound |
M,FP |
R7911 |
T9172 |
T9170 |
quantmod |
FP,8 |
R7912 |
T9173 |
T9166 |
punct |
.,maximal |
R7913 |
T9174 |
T9177 |
amod |
Subsequent,translocation |
R7914 |
T9175 |
T9177 |
nmod |
GR,translocation |
R7915 |
T9176 |
T9177 |
amod |
nuclear,translocation |
R7916 |
T9177 |
T9178 |
nsubj |
translocation,was |
R7917 |
T9178 |
T9178 |
ROOT |
was,was |
R7918 |
T9179 |
T9178 |
acomp |
rapid,was |
R7919 |
T9180 |
T9178 |
cc |
and,was |
R792 |
T467 |
T465 |
pobj |
Action,of |
R7920 |
T9181 |
T9178 |
conj |
sustained,was |
R7921 |
T9182 |
T9181 |
prep |
at,sustained |
R7922 |
T9183 |
T9184 |
amod |
significant,levels |
R7923 |
T9184 |
T9182 |
pobj |
levels,at |
R7924 |
T9185 |
T9181 |
prep |
for,sustained |
R7925 |
T9186 |
T9187 |
advmod |
at,least |
R7926 |
T9187 |
T9188 |
advmod |
least,14 |
R7927 |
T9188 |
T9189 |
nummod |
14,h |
R7928 |
T9189 |
T9185 |
pobj |
h,for |
R7929 |
T9190 |
T9192 |
punct |
(,2B |
R793 |
T468 |
T467 |
prep |
in,Action |
R7930 |
T9191 |
T9192 |
compound |
Figure,2B |
R7931 |
T9192 |
T9189 |
appos |
2B,h |
R7932 |
T9193 |
T9192 |
punct |
),2B |
R7933 |
T9194 |
T9178 |
punct |
.,was |
R7934 |
T9195 |
T9199 |
advcl |
Using,showed |
R7935 |
T9196 |
T9197 |
amod |
IP-Western,blotting |
R7936 |
T9197 |
T9195 |
dobj |
blotting,Using |
R7937 |
T9198 |
T9199 |
nsubj |
we,showed |
R7938 |
T9199 |
T9199 |
ROOT |
showed,showed |
R7939 |
T9200 |
T9210 |
mark |
that,decreased |
R794 |
T469 |
T468 |
pobj |
Allergic,in |
R7940 |
T9201 |
T9210 |
nsubj |
FP,decreased |
R7941 |
T9202 |
T9201 |
prep |
at,FP |
R7942 |
T9203 |
T9205 |
nummod |
10,12 |
R7943 |
T9204 |
T9205 |
nummod |
−,12 |
R7944 |
T9205 |
T9202 |
pobj |
12,at |
R7945 |
T9206 |
T9209 |
nummod |
10,M |
R7946 |
T9207 |
T9209 |
nmod |
−,M |
R7947 |
T9208 |
T9207 |
nummod |
8,− |
R7948 |
T9209 |
T9201 |
conj |
M,FP |
R7949 |
T9210 |
T9199 |
ccomp |
decreased,showed |
R795 |
T470 |
T472 |
compound |
Disease,GATA-3 |
R7950 |
T9211 |
T9212 |
det |
the,association |
R7951 |
T9212 |
T9210 |
dobj |
association,decreased |
R7952 |
T9213 |
T9212 |
prep |
between,association |
R7953 |
T9214 |
T9213 |
pobj |
GATA-3,between |
R7954 |
T9215 |
T9214 |
cc |
and,GATA-3 |
R7955 |
T9216 |
T9214 |
conj |
importin-α,GATA-3 |
R7956 |
T9217 |
T9212 |
acl |
induced,association |
R7957 |
T9218 |
T9217 |
agent |
by,induced |
R7958 |
T9219 |
T9222 |
amod |
anti-CD3,stimulation |
R7959 |
T9220 |
T9222 |
nmod |
/,stimulation |
R796 |
T471 |
T472 |
compound |
Background,GATA-3 |
R7960 |
T9221 |
T9222 |
nummod |
CD28,stimulation |
R7961 |
T9222 |
T9218 |
pobj |
stimulation,by |
R7962 |
T9223 |
T9217 |
prep |
in,induced |
R7963 |
T9224 |
T9226 |
det |
a,manner |
R7964 |
T9225 |
T9226 |
amod |
concentration-dependent,manner |
R7965 |
T9226 |
T9223 |
pobj |
manner,in |
R7966 |
T9227 |
T9228 |
punct |
(,Figure |
R7967 |
T9228 |
T9226 |
appos |
Figure,manner |
R7968 |
T9229 |
T9228 |
npadvmod |
2C,Figure |
R7969 |
T9230 |
T9228 |
punct |
),Figure |
R797 |
T472 |
T473 |
nsubj |
GATA-3,plays |
R7970 |
T9231 |
T9199 |
punct |
.,showed |
R7971 |
T9232 |
T9242 |
prep |
In,demonstrated |
R7972 |
T9233 |
T9232 |
pobj |
addition,In |
R7973 |
T9234 |
T9242 |
punct |
",",demonstrated |
R7974 |
T9235 |
T9242 |
advcl |
using,demonstrated |
R7975 |
T9236 |
T9237 |
amod |
GFP-labelled,GATA-3 |
R7976 |
T9237 |
T9235 |
dobj |
GATA-3,using |
R7977 |
T9238 |
T9237 |
cc |
and,GATA-3 |
R7978 |
T9239 |
T9240 |
amod |
confocal,microscopy |
R7979 |
T9240 |
T9237 |
conj |
microscopy,GATA-3 |
R798 |
T473 |
T473 |
ROOT |
plays,plays |
R7980 |
T9241 |
T9242 |
nsubj |
we,demonstrated |
R7981 |
T9242 |
T9242 |
ROOT |
demonstrated,demonstrated |
R7982 |
T9243 |
T9256 |
mark |
that,attenuated |
R7983 |
T9244 |
T9246 |
amod |
GATA-3,import |
R7984 |
T9245 |
T9246 |
amod |
nuclear,import |
R7985 |
T9246 |
T9256 |
nsubjpass |
import,attenuated |
R7986 |
T9247 |
T9246 |
prep |
following,import |
R7987 |
T9248 |
T9249 |
compound |
anti-CD3,/ |
R7988 |
T9249 |
T9247 |
dobj |
/,following |
R7989 |
T9250 |
T9251 |
nummod |
CD28,stimulation |
R799 |
T474 |
T476 |
det |
a,role |
R7990 |
T9251 |
T9246 |
appos |
stimulation,import |
R7991 |
T9252 |
T9251 |
prep |
for,stimulation |
R7992 |
T9253 |
T9254 |
nummod |
30,min |
R7993 |
T9254 |
T9252 |
pobj |
min,for |
R7994 |
T9255 |
T9256 |
auxpass |
was,attenuated |
R7995 |
T9256 |
T9242 |
ccomp |
attenuated,demonstrated |
R7996 |
T9257 |
T9256 |
agent |
by,attenuated |
R7997 |
T9258 |
T9257 |
pobj |
pretreatment,by |
R7998 |
T9259 |
T9256 |
prep |
with,attenuated |
R7999 |
T9260 |
T9259 |
pobj |
FP,with |
R800 |
T475 |
T476 |
amod |
critical,role |
R8000 |
T9261 |
T9260 |
punct |
(,FP |
R8001 |
T9262 |
T9263 |
nummod |
10,− |
R8002 |
T9263 |
T9265 |
npadvmod |
−,M |
R8003 |
T9264 |
T9265 |
nummod |
8,M |
R8004 |
T9265 |
T9260 |
appos |
M,FP |
R8005 |
T9266 |
T9260 |
punct |
),FP |
R8006 |
T9267 |
T9268 |
punct |
(,Figure |
R8007 |
T9268 |
T9260 |
appos |
Figure,FP |
R8008 |
T9269 |
T9268 |
nummod |
2D,Figure |
R8009 |
T9270 |
T9242 |
punct |
),demonstrated |
R801 |
T476 |
T473 |
dobj |
role,plays |
R8010 |
T9271 |
T9242 |
punct |
.,demonstrated |
R8744 |
T10194 |
T10198 |
nsubj |
Effect,inhibits |
R8745 |
T10195 |
T10194 |
prep |
on,Effect |
R8746 |
T10196 |
T10197 |
compound |
MKP-1,Dexamethasone |
R8747 |
T10197 |
T10195 |
pobj |
Dexamethasone,on |
R8748 |
T10198 |
T10198 |
ROOT |
inhibits,inhibits |
R8749 |
T10199 |
T10201 |
nummod |
p38,function |
R8750 |
T10200 |
T10201 |
compound |
MAPK,function |
R8751 |
T10201 |
T10198 |
dobj |
function,inhibits |
R8752 |
T10202 |
T10201 |
prep |
in,function |
R8753 |
T10203 |
T10205 |
det |
a,type |
R8754 |
T10204 |
T10205 |
compound |
cell,type |
R8755 |
T10205 |
T10202 |
pobj |
type,in |
R8756 |
T10206 |
T10207 |
amod |
specific,manner |
R8757 |
T10207 |
T10201 |
conj |
manner,function |
R8758 |
T10208 |
T10198 |
prep |
through,inhibits |
R8759 |
T10209 |
T10211 |
det |
the,induction |
R8760 |
T10210 |
T10211 |
amod |
rapid,induction |
R8761 |
T10211 |
T10208 |
pobj |
induction,through |
R8762 |
T10212 |
T10211 |
prep |
of,induction |
R8763 |
T10213 |
T10215 |
det |
the,kinase |
R8764 |
T10214 |
T10215 |
amod |
dual,kinase |
R8765 |
T10215 |
T10212 |
pobj |
kinase,of |
R8766 |
T10216 |
T10217 |
compound |
phosphatase,MKP-1 |
R8767 |
T10217 |
T10215 |
appos |
MKP-1,kinase |
R8768 |
T10218 |
T10220 |
punct |
(,phosphatase-1 |
R8769 |
T10219 |
T10220 |
compound |
MAPK,phosphatase-1 |
R8770 |
T10220 |
T10217 |
appos |
phosphatase-1,MKP-1 |
R8771 |
T10221 |
T10220 |
punct |
),phosphatase-1 |
R8772 |
T10222 |
T10217 |
punct |
",",MKP-1 |
R8773 |
T10223 |
T10217 |
cc |
and,MKP-1 |
R8774 |
T10224 |
T10225 |
det |
this,effect |
R8775 |
T10225 |
T10226 |
nsubj |
effect,lasts |
R8776 |
T10226 |
T10215 |
relcl |
lasts,kinase |
R8777 |
T10227 |
T10226 |
prep |
for,lasts |
R8778 |
T10228 |
T10230 |
quantmod |
up,24 |
R8779 |
T10229 |
T10230 |
quantmod |
to,24 |
R8780 |
T10230 |
T10234 |
nummod |
24,] |
R8781 |
T10231 |
T10232 |
compound |
h,[ |
R8782 |
T10232 |
T10234 |
nmod |
[,] |
R8783 |
T10233 |
T10232 |
nummod |
28,[ |
R8784 |
T10234 |
T10227 |
pobj |
],for |
R8785 |
T10235 |
T10198 |
punct |
.,inhibits |
R8786 |
T10236 |
T10243 |
nmod |
FP,treatment |
R8787 |
T10237 |
T10239 |
punct |
(,− |
R8788 |
T10238 |
T10239 |
nummod |
10,− |
R8789 |
T10239 |
T10243 |
nmod |
−,treatment |
R8790 |
T10240 |
T10239 |
nummod |
8,− |
R8791 |
T10241 |
T10239 |
appos |
M,− |
R8792 |
T10242 |
T10239 |
punct |
),− |
R8793 |
T10243 |
T10255 |
nsubj |
treatment,decreased |
R8794 |
T10244 |
T10243 |
prep |
of,treatment |
R8795 |
T10245 |
T10246 |
amod |
HuT-78,cells |
R8796 |
T10246 |
T10244 |
pobj |
cells,of |
R8797 |
T10247 |
T10246 |
acl |
activated,cells |
R8798 |
T10248 |
T10247 |
agent |
by,activated |
R8799 |
T10249 |
T10250 |
compound |
anti-CD3,/ |
R8800 |
T10250 |
T10248 |
pobj |
/,by |
R8801 |
T10251 |
T10250 |
nummod |
CD28,/ |
R8802 |
T10252 |
T10247 |
prep |
in,activated |
R8803 |
T10253 |
T10252 |
pobj |
vitro,in |
R8804 |
T10254 |
T10255 |
advmod |
significantly,decreased |
R8805 |
T10255 |
T10255 |
ROOT |
decreased,decreased |
R8806 |
T10256 |
T10258 |
nummod |
p38,phosphorylation |
R8807 |
T10257 |
T10258 |
compound |
MAPK,phosphorylation |
R8808 |
T10258 |
T10255 |
dobj |
phosphorylation,decreased |
R8809 |
T10259 |
T10261 |
punct |
(,3A |
R8810 |
T10260 |
T10261 |
compound |
Figure,3A |
R8811 |
T10261 |
T10258 |
appos |
3A,phosphorylation |
R8812 |
T10262 |
T10258 |
punct |
),phosphorylation |
R8813 |
T10263 |
T10258 |
cc |
and,phosphorylation |
R8814 |
T10264 |
T10258 |
conj |
activity,phosphorylation |
R8815 |
T10265 |
T10255 |
conj |
measured,decreased |
R8816 |
T10266 |
T10265 |
agent |
by,measured |
R8817 |
T10267 |
T10266 |
pobj |
phosphorylation,by |
R8818 |
T10268 |
T10267 |
prep |
of,phosphorylation |
R8819 |
T10269 |
T10271 |
det |
the,target |
R8820 |
T10270 |
T10271 |
amod |
downstream,target |
R8821 |
T10271 |
T10268 |
pobj |
target,of |
R8822 |
T10272 |
T10271 |
appos |
ATF-2,target |
R8823 |
T10273 |
T10275 |
punct |
(,3B |
R8824 |
T10274 |
T10275 |
compound |
Figure,3B |
R8825 |
T10275 |
T10272 |
appos |
3B,ATF-2 |
R8826 |
T10276 |
T10272 |
punct |
),ATF-2 |
R8827 |
T10277 |
T10255 |
punct |
.,decreased |
R8828 |
T10278 |
T10279 |
det |
This,effect |
R8829 |
T10279 |
T10281 |
nsubjpass |
effect,detected |
R8830 |
T10280 |
T10281 |
auxpass |
was,detected |
R8831 |
T10281 |
T10281 |
ROOT |
detected,detected |
R8832 |
T10282 |
T10281 |
prep |
at,detected |
R8833 |
T10283 |
T10284 |
nummod |
30,min |
R8834 |
T10284 |
T10282 |
pobj |
min,at |
R8835 |
T10285 |
T10281 |
cc |
and,detected |
R8836 |
T10286 |
T10281 |
conj |
lasted,detected |
R8837 |
T10287 |
T10286 |
prep |
for,lasted |
R8838 |
T10288 |
T10289 |
advmod |
at,least |
R8839 |
T10289 |
T10290 |
advmod |
least,14 |
R8840 |
T10290 |
T10291 |
nummod |
14,h |
R8841 |
T10291 |
T10287 |
pobj |
h,for |
R8842 |
T10292 |
T10294 |
punct |
(,3B |
R8843 |
T10293 |
T10294 |
compound |
Figure,3B |
R8844 |
T10294 |
T10291 |
appos |
3B,h |
R8845 |
T10295 |
T10291 |
punct |
),h |
R8846 |
T10296 |
T10281 |
punct |
.,detected |
R8847 |
T10297 |
T10306 |
nsubj |
FP,reduced |
R8848 |
T10298 |
T10300 |
punct |
(,− |
R8849 |
T10299 |
T10300 |
nummod |
10,− |
R8850 |
T10300 |
T10306 |
nsubj |
−,reduced |
R8851 |
T10301 |
T10300 |
nummod |
8,− |
R8852 |
T10302 |
T10300 |
appos |
M,− |
R8853 |
T10303 |
T10300 |
punct |
),− |
R8854 |
T10304 |
T10306 |
advmod |
also,reduced |
R8855 |
T10305 |
T10306 |
advmod |
significantly,reduced |
R8856 |
T10306 |
T10306 |
ROOT |
reduced,reduced |
R8857 |
T10307 |
T10309 |
nmod |
GATA-3,phosphorylation |
R8858 |
T10308 |
T10309 |
compound |
serine,phosphorylation |
R8859 |
T10309 |
T10306 |
dobj |
phosphorylation,reduced |
R8860 |
T10310 |
T10309 |
acl |
induced,phosphorylation |
R8861 |
T10311 |
T10310 |
agent |
by,induced |
R8862 |
T10312 |
T10315 |
amod |
anti-CD3,stimulation |
R8863 |
T10313 |
T10315 |
nmod |
/,stimulation |
R8864 |
T10314 |
T10315 |
nummod |
CD28,stimulation |
R8865 |
T10315 |
T10311 |
pobj |
stimulation,by |
R8866 |
T10316 |
T10315 |
prep |
in,stimulation |
R8867 |
T10317 |
T10319 |
preconj |
both,time |
R8868 |
T10318 |
T10319 |
det |
a,time |
R8869 |
T10319 |
T10316 |
pobj |
time,in |
R8870 |
T10320 |
T10319 |
punct |
-,time |
R8871 |
T10321 |
T10319 |
cc |
and,time |
R8872 |
T10322 |
T10323 |
amod |
concentration-dependent,manner |
R8873 |
T10323 |
T10319 |
conj |
manner,time |
R8874 |
T10324 |
T10326 |
punct |
(,3C |
R8875 |
T10325 |
T10326 |
compound |
Figure,3C |
R8876 |
T10326 |
T10323 |
appos |
3C,manner |
R8877 |
T10327 |
T10326 |
punct |
),3C |
R8878 |
T10328 |
T10306 |
punct |
.,reduced |
R8879 |
T10329 |
T10330 |
det |
This,reduction |
R8880 |
T10330 |
T10336 |
nsubjpass |
reduction,seen |
R8881 |
T10331 |
T10330 |
prep |
in,reduction |
R8882 |
T10332 |
T10333 |
amod |
GATA-3,phosphorylation |
R8883 |
T10333 |
T10331 |
pobj |
phosphorylation,in |
R8884 |
T10334 |
T10336 |
auxpass |
was,seen |
R8885 |
T10335 |
T10336 |
advmod |
also,seen |
R8886 |
T10336 |
T10336 |
ROOT |
seen,seen |
R8887 |
T10337 |
T10336 |
prep |
with,seen |
R8888 |
T10338 |
T10339 |
amod |
lower,concentrations |
R8889 |
T10339 |
T10337 |
pobj |
concentrations,with |
R8890 |
T10340 |
T10339 |
prep |
of,concentrations |
R8891 |
T10341 |
T10340 |
pobj |
FP,of |
R8892 |
T10342 |
T10336 |
punct |
.,seen |
R8893 |
T10343 |
T10344 |
nsubj |
We,found |
R8894 |
T10344 |
T10344 |
ROOT |
found,found |
R8895 |
T10345 |
T10348 |
mark |
that,induced |
R8896 |
T10346 |
T10348 |
nsubj |
FP,induced |
R8897 |
T10347 |
T10348 |
advmod |
significantly,induced |
R8898 |
T10348 |
T10344 |
ccomp |
induced,found |
R8899 |
T10349 |
T10350 |
compound |
MKP-1,mRNA |
R8900 |
T10350 |
T10348 |
dobj |
mRNA,induced |
R8901 |
T10351 |
T10348 |
prep |
in,induced |
R8902 |
T10352 |
T10354 |
predet |
both,time |
R8903 |
T10353 |
T10354 |
det |
a,time |
R8904 |
T10354 |
T10351 |
pobj |
time,in |
R8905 |
T10355 |
T10348 |
punct |
-,induced |
R8906 |
T10356 |
T10348 |
cc |
and,induced |
R8907 |
T10357 |
T10358 |
amod |
concentration-dependent,manner |
R8908 |
T10358 |
T10348 |
conj |
manner,induced |
R8909 |
T10359 |
T10358 |
punct |
",",manner |
R8910 |
T10360 |
T10358 |
acl |
reaching,manner |
R8911 |
T10361 |
T10362 |
det |
a,plateau |
R8912 |
T10362 |
T10360 |
dobj |
plateau,reaching |
R8913 |
T10363 |
T10360 |
prep |
at,reaching |
R8914 |
T10364 |
T10365 |
nummod |
10,− |
R8915 |
T10365 |
T10367 |
compound |
−,M |
R8916 |
T10366 |
T10367 |
compound |
8,M |
R8917 |
T10367 |
T10363 |
pobj |
M,at |
R8918 |
T10368 |
T10360 |
prep |
after,reaching |
R8919 |
T10369 |
T10370 |
nummod |
10,min |
R8920 |
T10370 |
T10368 |
pobj |
min,after |
R8921 |
T10371 |
T10372 |
punct |
(,Figure |
R8922 |
T10372 |
T10376 |
nmod |
Figure,) |
R8923 |
T10373 |
T10372 |
nummod |
3D,Figure |
R8924 |
T10374 |
T10372 |
cc |
and,Figure |
R8925 |
T10375 |
T10372 |
conj |
3E,Figure |
R8926 |
T10376 |
T10358 |
punct |
),manner |
R8927 |
T10377 |
T10344 |
punct |
.,found |
R8928 |
T10378 |
T10396 |
advmod |
However,seen |
R8929 |
T10379 |
T10396 |
punct |
",",seen |
R8930 |
T10380 |
T10381 |
det |
the,effects |
R8931 |
T10381 |
T10396 |
nsubjpass |
effects,seen |
R8932 |
T10382 |
T10381 |
prep |
of,effects |
R8933 |
T10383 |
T10382 |
pobj |
FP,of |
R8934 |
T10384 |
T10381 |
prep |
on,effects |
R8935 |
T10385 |
T10387 |
nmod |
GATA-3,import |
R8936 |
T10386 |
T10387 |
amod |
nuclear,import |
R8937 |
T10387 |
T10384 |
pobj |
import,on |
R8938 |
T10388 |
T10387 |
punct |
",",import |
R8939 |
T10389 |
T10390 |
amod |
importin-α,association |
R8940 |
T10390 |
T10387 |
conj |
association,import |
R8941 |
T10391 |
T10390 |
cc |
and,association |
R8942 |
T10392 |
T10390 |
conj |
IL-4,association |
R8943 |
T10393 |
T10394 |
compound |
mRNA,expression |
R8944 |
T10394 |
T10390 |
conj |
expression,association |
R8945 |
T10395 |
T10396 |
auxpass |
are,seen |
R8946 |
T10396 |
T10396 |
ROOT |
seen,seen |
R8947 |
T10397 |
T10396 |
prep |
at,seen |
R8948 |
T10398 |
T10400 |
nummod |
"10,000-fold",concentrations |
R8949 |
T10399 |
T10400 |
amod |
lower,concentrations |
R8950 |
T10400 |
T10397 |
pobj |
concentrations,at |
R8951 |
T10401 |
T10400 |
punct |
(,concentrations |
R8952 |
T10402 |
T10403 |
nummod |
10,− |
R8953 |
T10403 |
T10400 |
appos |
−,concentrations |
R8954 |
T10404 |
T10405 |
nummod |
12,M |
R8955 |
T10405 |
T10403 |
appos |
M,− |
R8956 |
T10406 |
T10403 |
punct |
",",− |
R8957 |
T10407 |
T10408 |
compound |
see,Figure |
R8958 |
T10408 |
T10400 |
appos |
Figure,concentrations |
R8959 |
T10409 |
T10408 |
nummod |
2,Figure |
R8960 |
T10410 |
T10408 |
punct |
),Figure |
R8961 |
T10411 |
T10396 |
punct |
.,seen |
R8962 |
T10412 |
T10434 |
advcl |
Using,demonstrated |
R8963 |
T10413 |
T10417 |
det |
an,assay |
R8964 |
T10414 |
T10417 |
nmod |
in,assay |
R8965 |
T10415 |
T10416 |
amod |
vitro,competition |
R8966 |
T10416 |
T10417 |
compound |
competition,assay |
R8967 |
T10417 |
T10412 |
dobj |
assay,Using |
R8968 |
T10418 |
T10420 |
punct |
(,4A |
R8969 |
T10419 |
T10420 |
compound |
Figure,4A |
R8970 |
T10420 |
T10417 |
appos |
4A,assay |
R8971 |
T10421 |
T10420 |
punct |
),4A |
R8972 |
T10422 |
T10417 |
acl |
utilizing,assay |
R8973 |
T10423 |
T10425 |
amod |
purified,GATA-3 |
R8974 |
T10424 |
T10425 |
amod |
activated,GATA-3 |
R8975 |
T10425 |
T10422 |
dobj |
GATA-3,utilizing |
R8976 |
T10426 |
T10425 |
punct |
",",GATA-3 |
R8977 |
T10427 |
T10425 |
conj |
importin-α,GATA-3 |
R8978 |
T10428 |
T10412 |
punct |
",",Using |
R8979 |
T10429 |
T10412 |
cc |
and,Using |
R8980 |
T10430 |
T10434 |
advcl |
activated,demonstrated |
R8981 |
T10431 |
T10430 |
dobj |
GR,activated |
R8982 |
T10432 |
T10434 |
punct |
",",demonstrated |
R8983 |
T10433 |
T10434 |
nsubj |
we,demonstrated |
R8984 |
T10434 |
T10434 |
ROOT |
demonstrated,demonstrated |
R8985 |
T10435 |
T10436 |
mark |
that,activated |
R8986 |
T10436 |
T10434 |
ccomp |
activated,demonstrated |
R8987 |
T10437 |
T10439 |
nsubj |
GR,increased |
R8988 |
T10438 |
T10439 |
advmod |
significantly,increased |
R8989 |
T10439 |
T10434 |
conj |
increased,demonstrated |
R8990 |
T10440 |
T10441 |
amod |
GR-importin-α,association |
R8991 |
T10441 |
T10439 |
dobj |
association,increased |
R8992 |
T10442 |
T10439 |
prep |
in,increased |
R8993 |
T10443 |
T10444 |
det |
the,presence |
R8994 |
T10444 |
T10442 |
pobj |
presence,in |
R8995 |
T10445 |
T10444 |
cc |
and,presence |
R8996 |
T10446 |
T10444 |
conj |
absence,presence |
R8997 |
T10447 |
T10446 |
prep |
of,absence |
R8998 |
T10448 |
T10449 |
amod |
activated,GATA-3 |
R8999 |
T10449 |
T10447 |
pobj |
GATA-3,of |
R9000 |
T10450 |
T10452 |
punct |
(,4B |
R9001 |
T10451 |
T10452 |
compound |
Figure,4B |
R9002 |
T10452 |
T10449 |
appos |
4B,GATA-3 |
R9003 |
T10453 |
T10449 |
punct |
),GATA-3 |
R9004 |
T10454 |
T10439 |
punct |
.,increased |
R9005 |
T10455 |
T10456 |
det |
This,effect |
R9006 |
T10456 |
T10457 |
nsubj |
effect,is |
R9007 |
T10457 |
T10457 |
ROOT |
is,is |
R9008 |
T10458 |
T10457 |
neg |
not,is |
R9009 |
T10459 |
T10457 |
acomp |
mutual,is |
R9010 |
T10460 |
T10457 |
punct |
",",is |
R9011 |
T10461 |
T10462 |
mark |
since,activated |
R9012 |
T10462 |
T10466 |
advcl |
activated,block |
R9013 |
T10463 |
T10466 |
nsubj |
GATA-3,block |
R9014 |
T10464 |
T10466 |
aux |
did,block |
R9015 |
T10465 |
T10466 |
neg |
not,block |
R9016 |
T10466 |
T10457 |
advcl |
block,is |
R9017 |
T10467 |
T10466 |
dobj |
GR,block |
R9018 |
T10468 |
T10469 |
amod |
importin-α,association |
R9019 |
T10469 |
T10466 |
dep |
association,block |
R9020 |
T10470 |
T10471 |
punct |
(,Figure |
R9021 |
T10471 |
T10472 |
nmod |
Figure,4C |
R9022 |
T10472 |
T10469 |
appos |
4C,association |
R9023 |
T10473 |
T10469 |
punct |
),association |
R9024 |
T10474 |
T10457 |
punct |
.,is |
R9025 |
T10475 |
T10476 |
det |
These,data |
R9026 |
T10476 |
T10478 |
nsubj |
data,suggest |
R9027 |
T10477 |
T10478 |
advmod |
also,suggest |
R9028 |
T10478 |
T10478 |
ROOT |
suggest,suggest |
R9029 |
T10479 |
T10481 |
mark |
that,activated |
R9030 |
T10480 |
T10481 |
nsubj |
both,activated |
R9031 |
T10481 |
T10478 |
ccomp |
activated,suggest |
R9032 |
T10482 |
T10481 |
dobj |
GR,activated |
R9033 |
T10483 |
T10482 |
cc |
and,GR |
R9034 |
T10484 |
T10482 |
conj |
phospho-GATA-3,GR |
R9035 |
T10485 |
T10487 |
aux |
can,associate |
R9036 |
T10486 |
T10487 |
advmod |
directly,associate |
R9037 |
T10487 |
T10478 |
ccomp |
associate,suggest |
R9038 |
T10488 |
T10487 |
prep |
with,associate |
R9039 |
T10489 |
T10488 |
pobj |
importin-α,with |
R9040 |
T10490 |
T10492 |
punct |
(,4D |
R9041 |
T10491 |
T10492 |
compound |
Figure,4D |
R9042 |
T10492 |
T10489 |
appos |
4D,importin-α |
R9043 |
T10493 |
T10492 |
punct |
),4D |
R9044 |
T10494 |
T10487 |
cc |
and,associate |
R9045 |
T10495 |
T10496 |
nsubj |
that,activated |
R9046 |
T10496 |
T10487 |
conj |
activated,associate |
R9047 |
T10497 |
T10498 |
compound |
GR,attenuates |
R9048 |
T10498 |
T10498 |
ROOT |
attenuates,attenuates |
R9049 |
T10499 |
T10503 |
det |
the,interaction |
R9050 |
T10500 |
T10503 |
amod |
phospho-GATA-3,interaction |
R9051 |
T10501 |
T10503 |
nmod |
/,interaction |
R9052 |
T10502 |
T10503 |
amod |
importin-α,interaction |
R9053 |
T10503 |
T10498 |
dobj |
interaction,attenuates |
R9054 |
T10504 |
T10498 |
prep |
in,attenuates |
R9055 |
T10505 |
T10507 |
det |
a,manner |
R9056 |
T10506 |
T10507 |
amod |
concentration-dependent,manner |
R9057 |
T10507 |
T10504 |
pobj |
manner,in |
R9058 |
T10508 |
T10509 |
punct |
(,Figure |
R9059 |
T10509 |
T10498 |
appos |
Figure,attenuates |
R9060 |
T10510 |
T10509 |
nummod |
4E,Figure |
R9061 |
T10511 |
T10509 |
punct |
),Figure |
R9062 |
T10512 |
T10478 |
punct |
.,suggest |
R9063 |
T10513 |
T10516 |
advmod |
Together,suggests |
R9064 |
T10514 |
T10516 |
punct |
",",suggests |
R9065 |
T10515 |
T10516 |
nsubj |
this,suggests |
R9066 |
T10516 |
T10516 |
ROOT |
suggests,suggests |
R9067 |
T10517 |
T10521 |
mark |
that,compete |
R9068 |
T10518 |
T10519 |
compound |
ligand-activated,GR |
R9069 |
T10519 |
T10521 |
nsubj |
GR,compete |
R9070 |
T10520 |
T10521 |
aux |
may,compete |
R9071 |
T10521 |
T10516 |
ccomp |
compete,suggests |
R9072 |
T10522 |
T10521 |
prep |
with,compete |
R9073 |
T10523 |
T10522 |
pobj |
phospho-GATA-3,with |
R9074 |
T10524 |
T10523 |
prep |
for,phospho-GATA-3 |
R9075 |
T10525 |
T10524 |
pobj |
importin-α,for |
R9076 |
T10526 |
T10525 |
cc |
and,importin-α |
R9077 |
T10527 |
T10528 |
advmod |
thereby,limit |
R9078 |
T10528 |
T10525 |
conj |
limit,importin-α |
R9079 |
T10529 |
T10531 |
amod |
GATA-3,import |
R9080 |
T10530 |
T10531 |
amod |
nuclear,import |
R9081 |
T10531 |
T10528 |
dobj |
import,limit |
R9082 |
T10532 |
T10516 |
punct |
.,suggests |
R9083 |
T10533 |
T10535 |
amod |
Other,interpretations |
R9084 |
T10534 |
T10535 |
amod |
possible,interpretations |
R9085 |
T10535 |
T10540 |
nsubj |
interpretations,include |
R9086 |
T10536 |
T10535 |
prep |
of,interpretations |
R9087 |
T10537 |
T10538 |
poss |
our,results |
R9088 |
T10538 |
T10536 |
pobj |
results,of |
R9089 |
T10539 |
T10540 |
aux |
could,include |
R9090 |
T10540 |
T10540 |
ROOT |
include,include |
R9091 |
T10541 |
T10542 |
det |
an,effect |
R9092 |
T10542 |
T10540 |
dobj |
effect,include |
R9093 |
T10543 |
T10542 |
prep |
of,effect |
R9094 |
T10544 |
T10543 |
pobj |
FP,of |
R9095 |
T10545 |
T10542 |
prep |
on,effect |
R9096 |
T10546 |
T10548 |
nmod |
GATA-3,export |
R9097 |
T10547 |
T10548 |
amod |
nuclear,export |
R9098 |
T10548 |
T10545 |
pobj |
export,on |
R9099 |
T10549 |
T10548 |
cc |
and/or,export |
R9100 |
T10550 |
T10548 |
conj |
degradation,export |
R9101 |
T10551 |
T10540 |
punct |
.,include |
R9102 |
T10552 |
T10553 |
compound |
Leptomycin,B |
R9103 |
T10553 |
T10562 |
nsubj |
B,affect |
R9104 |
T10554 |
T10553 |
punct |
",",B |
R9105 |
T10555 |
T10556 |
nsubj |
which,inhibits |
R9106 |
T10556 |
T10553 |
relcl |
inhibits,B |
R9107 |
T10557 |
T10558 |
amod |
nuclear,export |
R9108 |
T10558 |
T10556 |
dobj |
export,inhibits |
R9109 |
T10559 |
T10562 |
punct |
",",affect |
R9110 |
T10560 |
T10562 |
aux |
did,affect |
R9111 |
T10561 |
T10562 |
neg |
not,affect |
R9112 |
T10562 |
T10562 |
ROOT |
affect,affect |
R9113 |
T10563 |
T10564 |
det |
the,ability |
R9114 |
T10564 |
T10562 |
dobj |
ability,affect |
R9115 |
T10565 |
T10564 |
prep |
of,ability |
R9116 |
T10566 |
T10565 |
pobj |
FP,of |
R9117 |
T10567 |
T10568 |
aux |
to,block |
R9118 |
T10568 |
T10564 |
acl |
block,ability |
R9119 |
T10569 |
T10571 |
amod |
GATA-3,localization |
R9120 |
T10570 |
T10571 |
amod |
nuclear,localization |
R9121 |
T10571 |
T10568 |
dobj |
localization,block |
R9122 |
T10572 |
T10574 |
punct |
(,5A |
R9123 |
T10573 |
T10574 |
compound |
Figure,5A |
R9124 |
T10574 |
T10571 |
appos |
5A,localization |
R9125 |
T10575 |
T10574 |
punct |
),5A |
R9126 |
T10576 |
T10562 |
punct |
.,affect |
R9127 |
T10577 |
T10580 |
advmod |
Additionally,had |
R9128 |
T10578 |
T10580 |
punct |
",",had |
R9129 |
T10579 |
T10580 |
nsubj |
FP,had |
R9130 |
T10580 |
T10580 |
ROOT |
had,had |
R9131 |
T10581 |
T10582 |
det |
no,effect |
R9132 |
T10582 |
T10580 |
dobj |
effect,had |
R9133 |
T10583 |
T10582 |
prep |
on,effect |
R9134 |
T10584 |
T10587 |
amod |
whole,expression |
R9135 |
T10585 |
T10586 |
compound |
cell,GATA-3 |
R9136 |
T10586 |
T10587 |
compound |
GATA-3,expression |
R9137 |
T10587 |
T10583 |
pobj |
expression,on |
R9138 |
T10588 |
T10580 |
prep |
during,had |
R9139 |
T10589 |
T10591 |
det |
the,course |
R9140 |
T10590 |
T10591 |
compound |
time,course |
R9141 |
T10591 |
T10588 |
pobj |
course,during |
R9142 |
T10592 |
T10591 |
prep |
of,course |
R9143 |
T10593 |
T10594 |
det |
these,experiments |
R9144 |
T10594 |
T10592 |
pobj |
experiments,of |
R9145 |
T10595 |
T10597 |
punct |
(,5B |
R9146 |
T10596 |
T10597 |
compound |
Figure,5B |
R9147 |
T10597 |
T10594 |
appos |
5B,experiments |
R9148 |
T10598 |
T10597 |
punct |
),5B |
R9149 |
T10599 |
T10580 |
punct |
.,had |
R9150 |
T10600 |
T10602 |
cc |
Nor,addition |
R9151 |
T10601 |
T10602 |
aux |
did,addition |
R9152 |
T10602 |
T10602 |
ROOT |
addition,addition |
R9153 |
T10603 |
T10602 |
prep |
of,addition |
R9154 |
T10604 |
T10603 |
pobj |
FP,of |
R9155 |
T10605 |
T10602 |
advmod |
subsequent,addition |
R9156 |
T10606 |
T10607 |
aux |
to,anti-CD3 |
R9157 |
T10607 |
T10605 |
xcomp |
anti-CD3,subsequent |
R9158 |
T10608 |
T10611 |
nmod |
/,translocation |
R9159 |
T10609 |
T10608 |
nummod |
CD28,/ |
R9160 |
T10610 |
T10611 |
amod |
nuclear,translocation |
R9161 |
T10611 |
T10612 |
nsubj |
translocation,affect |
R9162 |
T10612 |
T10607 |
conj |
affect,anti-CD3 |
R9163 |
T10613 |
T10615 |
nmod |
GATA-3,residency |
R9164 |
T10614 |
T10615 |
amod |
nuclear,residency |
R9165 |
T10615 |
T10612 |
dobj |
residency,affect |
R9166 |
T10616 |
T10618 |
punct |
(,5C |
R9167 |
T10617 |
T10618 |
compound |
Figure,5C |
R9168 |
T10618 |
T10615 |
appos |
5C,residency |
R9169 |
T10619 |
T10615 |
punct |
),residency |
R9170 |
T10620 |
T10605 |
punct |
",",subsequent |
R9171 |
T10621 |
T10605 |
advcl |
suggesting,subsequent |
R9172 |
T10622 |
T10627 |
mark |
that,enhance |
R9173 |
T10623 |
T10624 |
amod |
activated,GR |
R9174 |
T10624 |
T10627 |
nsubj |
GR,enhance |
R9175 |
T10625 |
T10627 |
aux |
does,enhance |
R9176 |
T10626 |
T10627 |
neg |
not,enhance |
R9177 |
T10627 |
T10621 |
ccomp |
enhance,suggesting |
R9178 |
T10628 |
T10630 |
amod |
GATA-3,export |
R9179 |
T10629 |
T10630 |
amod |
nuclear,export |
R9180 |
T10630 |
T10627 |
dobj |
export,enhance |
R9181 |
T10631 |
T10605 |
punct |
.,subsequent |
R9182 |
T10632 |
T10642 |
advmod |
Finally,was |
R9183 |
T10633 |
T10642 |
punct |
",",was |
R9184 |
T10634 |
T10635 |
det |
the,effect |
R9185 |
T10635 |
T10642 |
nsubj |
effect,was |
R9186 |
T10636 |
T10635 |
prep |
of,effect |
R9187 |
T10637 |
T10636 |
pobj |
FP,of |
R9188 |
T10638 |
T10635 |
prep |
on,effect |
R9189 |
T10639 |
T10641 |
nmod |
GATA-3,import |
R9190 |
T10640 |
T10641 |
amod |
nuclear,import |
R9191 |
T10641 |
T10638 |
pobj |
import,on |
R9192 |
T10642 |
T10642 |
ROOT |
was,was |
R9193 |
T10643 |
T10642 |
neg |
not,was |
R9194 |
T10644 |
T10642 |
acomp |
nonspecific,was |
R9195 |
T10645 |
T10642 |
punct |
",",was |
R9196 |
T10646 |
T10654 |
mark |
since,had |
R9197 |
T10647 |
T10652 |
nmod |
FP,M |
R9198 |
T10648 |
T10650 |
punct |
(,− |
R9199 |
T10649 |
T10650 |
nummod |
10,− |
R9200 |
T10650 |
T10652 |
nmod |
−,M |
R9201 |
T10651 |
T10650 |
nummod |
8,− |
R9202 |
T10652 |
T10646 |
pobj |
M,since |
R9203 |
T10653 |
T10654 |
punct |
),had |
R9204 |
T10654 |
T10642 |
advcl |
had,was |
R9205 |
T10655 |
T10656 |
det |
no,effect |
R9206 |
T10656 |
T10654 |
dobj |
effect,had |
R9207 |
T10657 |
T10656 |
prep |
on,effect |
R9208 |
T10658 |
T10660 |
nummod |
p65,translocation |
R9209 |
T10659 |
T10660 |
amod |
nuclear,translocation |
R9210 |
T10660 |
T10657 |
pobj |
translocation,on |
R9211 |
T10661 |
T10654 |
conj |
measured,had |
R9212 |
T10662 |
T10661 |
prep |
at,measured |
R9213 |
T10663 |
T10664 |
nummod |
60,min |
R9214 |
T10664 |
T10662 |
pobj |
min,at |
R9215 |
T10665 |
T10666 |
punct |
(,Figure |
R9216 |
T10666 |
T10664 |
appos |
Figure,min |
R9217 |
T10667 |
T10666 |
nummod |
5D,Figure |
R9218 |
T10668 |
T10666 |
punct |
),Figure |
R9219 |
T10669 |
T10642 |
punct |
.,was |