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PMC:1942070 / 6818-8935 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4218 5-13 NNP denotes Cellular
T4219 14-27 NN denotes proliferation
T4220 28-31 CC denotes and
T4221 32-40 NN denotes survival
T4222 41-43 IN denotes in
T4223 44-48 NNP denotes DT40
T4224 49-50 NNP denotes B
T4225 51-56 NNS denotes cells
T4226 57-64 VBG denotes lacking
T4227 65-75 NN denotes expression
T4228 76-78 IN denotes of
T4229 79-82 NNP denotes PKD
T4230 83-89 NN denotes family
T4231 90-97 VBZ denotes kinases
T4232 98-101 NNP denotes PKD
T4233 102-109 NNS denotes enzymes
T4234 110-114 VBP denotes have
T4235 115-125 RB denotes previously
T4236 126-130 VBN denotes been
T4237 131-137 VBN denotes linked
T4238 138-140 TO denotes to
T4239 141-144 DT denotes the
T4240 145-155 NN denotes regulation
T4241 156-158 IN denotes of
T4242 159-163 NN denotes cell
T4243 164-177 NN denotes proliferation
T4244 178-181 CC denotes and
T4245 182-190 NN denotes survival
T4246 191-192 -LRB- denotes (
T4247 192-200 VBN denotes reviewed
T4248 201-203 IN denotes in
T4249 204-205 NNP denotes [
T4250 205-207 CD denotes 20
T4251 207-208 NNP denotes ]
T4252 208-209 -RRB- denotes )
T4253 209-210 . denotes .
T4254 211-213 TO denotes To
T4255 214-225 VB denotes investigate
T4256 226-229 DT denotes the
T4257 230-236 NN denotes effect
T4258 237-241 WDT denotes that
T4259 242-246 NN denotes loss
T4260 247-249 IN denotes of
T4261 250-253 NNP denotes PKD
T4262 254-261 NNS denotes kinases
T4263 262-265 VBD denotes had
T4264 266-268 IN denotes on
T4265 269-270 NNP denotes B
T4266 271-275 NN denotes cell
T4267 276-284 NN denotes survival
T4268 285-291 CC denotes and/or
T4269 292-305 NN denotes proliferation
T4270 306-308 PRP denotes we
T4271 309-317 VBD denotes cultured
T4272 318-327 JJ denotes wild-type
T4273 328-331 CC denotes and
T4274 332-340 JJ denotes PKD-null
T4275 341-346 NNS denotes cells
T4276 347-349 IN denotes in
T4277 350-353 DT denotes the
T4278 354-362 NN denotes presence
T4279 363-364 -LRB- denotes (
T4280 364-370 CD denotes PKD1/3
T4281 370-371 CD denotes −
T4282 371-372 NN denotes /
T4283 372-373 NN denotes −
T4284 373-374 : denotes :
T4285 375-384 NN denotes Flag-PKD3
T4286 384-385 NN denotes +
T4287 385-387 NN denotes ve
T4288 387-388 -RRB- denotes )
T4289 389-391 CC denotes or
T4290 392-399 NN denotes absence
T4291 400-401 -LRB- denotes (
T4292 401-407 CD denotes PKD1/3
T4293 407-408 CD denotes −
T4294 408-409 NN denotes /
T4295 409-410 NN denotes −
T4296 410-411 -RRB- denotes )
T4297 412-414 IN denotes of
T4298 415-426 NN denotes doxycycline
T4299 427-430 CC denotes and
T4300 431-440 VBD denotes monitored
T4301 441-452 JJ denotes exponential
T4302 453-459 NN denotes growth
T4303 459-460 . denotes .
T4304 461-463 IN denotes As
T4305 464-469 VBN denotes shown
T4306 470-472 IN denotes in
T4307 473-477 NNP denotes Fig.
T4308 478-480 NNP denotes 2A
T4309 480-481 , denotes ,
T4310 482-488 NNP denotes PKD1/3
T4311 488-489 VBD denotes −
T4312 489-490 CD denotes /
T4313 490-491 NN denotes −
T4314 492-497 NNS denotes cells
T4315 498-510 VBD denotes proliferated
T4316 511-524 RB denotes exponentially
T4317 525-528 CC denotes and
T4318 529-542 NN denotes re-expression
T4319 543-545 IN denotes of
T4320 546-555 NN denotes Flag-PKD3
T4321 556-558 IN denotes in
T4322 559-564 DT denotes these
T4323 565-570 NNS denotes cells
T4324 571-574 VBD denotes had
T4325 575-577 DT denotes no
T4326 578-584 NN denotes impact
T4327 585-587 IN denotes on
T4328 588-591 DT denotes the
T4329 592-596 NN denotes rate
T4330 597-599 IN denotes of
T4331 600-613 NN denotes proliferation
T4332 613-614 . denotes .
T4333 615-626 RB denotes Furthermore
T4334 626-627 , denotes ,
T4335 628-631 DT denotes the
T4336 632-641 NN denotes viability
T4337 642-644 IN denotes of
T4338 645-651 CD denotes PKD1/3
T4339 651-652 CD denotes −
T4340 652-653 NN denotes /
T4341 653-654 NN denotes −
T4342 655-656 NNP denotes B
T4343 657-662 NNS denotes cells
T4344 663-669 IN denotes during
T4345 670-677 JJ denotes routine
T4346 678-687 NN denotes culturing
T4347 688-691 VBD denotes was
T4348 692-695 RB denotes not
T4349 696-709 RB denotes significantly
T4350 710-719 JJ denotes different
T4351 720-724 IN denotes from
T4352 725-729 DT denotes that
T4353 730-732 IN denotes of
T4354 733-742 JJ denotes wild-type
T4355 743-744 NNP denotes B
T4356 745-750 NNS denotes cells
T4357 751-752 -LRB- denotes (
T4358 752-756 NNS denotes data
T4359 757-760 RB denotes not
T4360 761-766 VBN denotes shown
T4361 766-767 -RRB- denotes )
T4362 767-768 . denotes .
T4363 769-771 PRP denotes It
T4364 772-775 VBD denotes was
T4365 776-781 VBN denotes noted
T4366 782-786 IN denotes that
T4367 787-790 DT denotes the
T4368 791-801 NN denotes population
T4369 802-810 VBG denotes doubling
T4370 811-815 NN denotes time
T4371 816-818 IN denotes of
T4372 819-825 CD denotes PKD1/3
T4373 825-826 CD denotes −
T4374 826-827 NN denotes /
T4375 827-828 NN denotes −
T4376 829-834 NNS denotes cells
T4377 835-838 VBD denotes was
T4378 839-847 RB denotes slightly
T4379 848-854 JJR denotes slower
T4380 855-859 IN denotes than
T4381 860-864 DT denotes that
T4382 865-867 IN denotes of
T4383 868-872 JJ denotes wild
T4384 873-877 NN denotes type
T4385 878-882 CD denotes DT40
T4386 883-888 NNS denotes cells
T4387 889-890 -LRB- denotes (
T4388 890-894 CD denotes 12.7
T4389 895-896 CD denotes ±
T4390 897-900 CD denotes 2.8
T4391 901-902 NN denotes h
T4392 903-909 IN denotes versus
T4393 910-914 CD denotes 10.2
T4394 915-916 CD denotes ±
T4395 917-920 CD denotes 0.4
T4396 921-922 NN denotes h
T4397 922-923 -RRB- denotes )
T4398 924-927 CC denotes but
T4399 928-931 DT denotes the
T4400 932-939 NN denotes failure
T4401 940-942 IN denotes of
T4402 943-947 CD denotes PKD3
T4403 948-961 NN denotes re-expression
T4404 962-964 TO denotes to
T4405 965-971 VB denotes modify
T4406 972-975 DT denotes the
T4407 976-989 NN denotes proliferation
T4408 990-994 NN denotes rate
T4409 995-997 IN denotes of
T4410 998-1004 CD denotes PKD1/3
T4411 1004-1005 CD denotes −
T4412 1005-1006 NN denotes /
T4413 1006-1007 NN denotes −
T4414 1008-1013 NNS denotes cells
T4415 1014-1022 VBZ denotes suggests
T4416 1023-1027 IN denotes that
T4417 1028-1033 DT denotes these
T4418 1034-1039 JJ denotes small
T4419 1040-1051 NNS denotes differences
T4420 1052-1056 VBD denotes were
T4421 1057-1061 RBS denotes most
T4422 1062-1068 JJ denotes likely
T4423 1069-1072 DT denotes the
T4424 1073-1079 NN denotes result
T4425 1080-1082 IN denotes of
T4426 1083-1089 JJ denotes clonal
T4427 1090-1099 NN denotes variation
T4428 1100-1103 CC denotes and
T4429 1104-1108 VBD denotes were
T4430 1109-1112 RB denotes not
T4431 1113-1119 VBN denotes caused
T4432 1120-1132 RB denotes specifically
T4433 1133-1135 IN denotes by
T4434 1136-1140 NN denotes loss
T4435 1141-1143 IN denotes of
T4436 1144-1147 NNP denotes PKD
T4437 1148-1155 VBZ denotes enzymes
T4438 1155-1156 . denotes .
T4439 1157-1161 RB denotes Thus
T4440 1161-1162 , denotes ,
T4441 1163-1166 NNP denotes PKD
T4442 1167-1173 NN denotes family
T4443 1174-1181 NNS denotes enzymes
T4444 1182-1185 VBP denotes are
T4445 1186-1189 RB denotes not
T4446 1190-1199 JJ denotes essential
T4447 1200-1203 IN denotes for
T4448 1204-1214 VBG denotes regulating
T4449 1215-1220 JJ denotes basal
T4450 1221-1229 NN denotes survival
T4451 1230-1233 CC denotes and
T4452 1234-1247 NN denotes proliferation
T4453 1248-1250 IN denotes of
T4454 1251-1255 NNP denotes DT40
T4455 1256-1257 NNP denotes B
T4456 1258-1263 NNS denotes cells
T4457 1263-1264 . denotes .
T4458 1265-1268 NNP denotes PKD
T4459 1269-1276 VBZ denotes enzymes
T4460 1276-1277 , denotes ,
T4461 1278-1290 RB denotes specifically
T4462 1291-1295 CD denotes PKD1
T4463 1296-1299 CC denotes and
T4464 1300-1304 NNP denotes PKD2
T4465 1304-1305 , denotes ,
T4466 1306-1310 VBP denotes have
T4467 1311-1321 RB denotes previously
T4468 1322-1326 VBN denotes been
T4469 1327-1333 VBN denotes linked
T4470 1334-1336 TO denotes to
T4471 1337-1338 DT denotes a
T4472 1339-1349 JJ denotes protective
T4473 1350-1354 NN denotes role
T4474 1355-1362 IN denotes against
T4475 1363-1372 JJ denotes oxidative
T4476 1373-1387 JJ denotes stress-induced
T4477 1388-1394 NN denotes injury
T4478 1395-1397 IN denotes in
T4479 1398-1401 NNP denotes 3T3
T4480 1402-1412 NN denotes fibroblast
T4481 1412-1413 , denotes ,
T4482 1414-1418 NNP denotes HeLa
T4483 1419-1422 CC denotes and
T4484 1423-1433 JJ denotes epithelial
T4485 1434-1438 NN denotes cell
T4486 1439-1444 NNS denotes lines
T4487 1445-1446 NNP denotes [
T4488 1446-1451 CD denotes 17,30
T4489 1452-1454 CD denotes 32
T4490 1454-1455 NN denotes ]
T4491 1455-1456 . denotes .
T4492 1457-1459 PRP denotes We
T4493 1460-1469 RB denotes therefore
T4494 1470-1479 VBD denotes addressed
T4495 1480-1483 DT denotes the
T4496 1484-1488 NN denotes role
T4497 1489-1491 IN denotes of
T4498 1492-1495 NNP denotes PKD
T4499 1496-1502 NN denotes family
T4500 1503-1510 NNS denotes kinases
T4501 1511-1513 IN denotes in
T4502 1514-1524 VBG denotes regulating
T4503 1525-1526 NNP denotes B
T4504 1527-1531 NN denotes cell
T4505 1532-1540 NN denotes survival
T4506 1541-1543 IN denotes in
T4507 1544-1552 NN denotes response
T4508 1553-1555 TO denotes to
T4509 1556-1565 JJ denotes oxidative
T4510 1566-1572 NN denotes stress
T4511 1573-1576 CC denotes and
T4512 1577-1582 JJ denotes other
T4513 1583-1589 NN denotes stress
T4514 1590-1597 NNS denotes stimuli
T4515 1597-1598 . denotes .
T4516 1599-1601 IN denotes As
T4517 1602-1607 VBN denotes shown
T4518 1608-1610 IN denotes in
T4519 1611-1615 NNP denotes Fig.
T4520 1616-1618 NNP denotes 2B
T4521 1618-1619 , denotes ,
T4522 1620-1624 NN denotes loss
T4523 1625-1627 IN denotes of
T4524 1628-1634 CD denotes PKD1/3
T4525 1635-1645 NN denotes expression
T4526 1646-1649 VBD denotes had
T4527 1650-1652 DT denotes no
T4528 1653-1664 JJ denotes significant
T4529 1665-1671 NN denotes impact
T4530 1672-1674 IN denotes on
T4531 1675-1678 DT denotes the
T4532 1679-1687 NN denotes survival
T4533 1688-1690 IN denotes of
T4534 1691-1695 NNP denotes DT40
T4535 1696-1697 NNP denotes B
T4536 1698-1703 NNS denotes cells
T4537 1704-1706 IN denotes in
T4538 1707-1715 NN denotes response
T4539 1716-1718 TO denotes to
T4540 1719-1732 JJ denotes mitochondrial
T4541 1733-1739 NN denotes stress
T4542 1740-1747 NNS denotes stimuli
T4543 1748-1749 -LRB- denotes (
T4544 1749-1753 CD denotes H2O2
T4545 1754-1756 CC denotes or
T4546 1757-1762 NN denotes serum
T4547 1763-1774 NN denotes deprivation
T4548 1774-1775 -RRB- denotes )
T4549 1775-1776 : denotes ;
T4550 1777-1780 NNP denotes DNA
T4551 1781-1789 VBG denotes damaging
T4552 1790-1796 NNS denotes agents
T4553 1797-1798 -LRB- denotes (
T4554 1798-1807 NN denotes etoposide
T4555 1808-1810 CC denotes or
T4556 1811-1822 NN denotes doxorubicin
T4557 1822-1823 -RRB- denotes )
T4558 1823-1824 : denotes ;
T4559 1825-1827 NNP denotes ER
T4560 1828-1835 NN denotes pathway
T4561 1836-1842 NN denotes stress
T4562 1843-1846 JJ denotes due
T4563 1847-1849 TO denotes to
T4564 1850-1857 NN denotes calcium
T4565 1858-1866 NN denotes overload
T4566 1867-1868 -LRB- denotes (
T4567 1868-1880 NN denotes thapsigargin
T4568 1880-1881 -RRB- denotes )
T4569 1882-1884 CC denotes or
T4570 1885-1894 VBG denotes following
T4571 1895-1904 JJ denotes prolonged
T4572 1905-1914 NN denotes treatment
T4573 1915-1919 IN denotes with
T4574 1920-1927 NN denotes phorbol
T4575 1928-1934 NNS denotes esters
T4576 1935-1937 CC denotes or
T4577 1938-1950 NNP denotes Trichostatin
T4578 1951-1952 NNP denotes A
T4579 1952-1953 , denotes ,
T4580 1954-1956 DT denotes an
T4581 1957-1966 NN denotes inhibitor
T4582 1967-1969 IN denotes of
T4583 1970-1975 NN denotes class
T4584 1976-1980 NNP denotes I/II
T4585 1981-1986 NNP denotes HDACs
T4586 1986-1987 . denotes .
T4587 1988-1992 RB denotes Thus
T4588 1992-1993 , denotes ,
T4589 1994-1997 NNP denotes PKD
T4590 1998-2005 NNS denotes kinases
T4591 2006-2008 VBP denotes do
T4592 2009-2012 RB denotes not
T4593 2013-2017 VB denotes play
T4594 2018-2020 DT denotes an
T4595 2021-2030 JJ denotes essential
T4596 2031-2035 NN denotes role
T4597 2036-2038 IN denotes in
T4598 2039-2049 VBG denotes regulating
T4599 2050-2051 NNP denotes B
T4600 2052-2056 NN denotes cell
T4601 2057-2065 NN denotes survival
T4602 2066-2068 IN denotes in
T4603 2069-2077 NN denotes response
T4604 2078-2080 TO denotes to
T4605 2081-2082 DT denotes a
T4606 2083-2088 NN denotes range
T4607 2089-2091 IN denotes of
T4608 2092-2101 JJ denotes different
T4609 2102-2108 NN denotes stress
T4610 2109-2116 NNS denotes stimuli
T4611 2116-2117 . denotes .
R3417 T4218 T4219 compound Cellular,proliferation
R3418 T4219 T4231 nsubj proliferation,kinases
R3419 T4220 T4219 cc and,proliferation
R3420 T4221 T4219 conj survival,proliferation
R3421 T4222 T4219 prep in,proliferation
R3422 T4223 T4224 compound DT40,B
R3423 T4224 T4225 compound B,cells
R3424 T4225 T4222 pobj cells,in
R3425 T4226 T4231 advcl lacking,kinases
R3426 T4227 T4226 dobj expression,lacking
R3427 T4228 T4227 prep of,expression
R3428 T4229 T4230 compound PKD,family
R3429 T4230 T4228 pobj family,of
R3430 T4231 T4231 ROOT kinases,kinases
R3431 T4232 T4233 compound PKD,enzymes
R3432 T4233 T4237 nsubjpass enzymes,linked
R3433 T4234 T4237 aux have,linked
R3434 T4235 T4237 advmod previously,linked
R3435 T4236 T4237 auxpass been,linked
R3436 T4237 T4231 ccomp linked,kinases
R3437 T4238 T4237 prep to,linked
R3438 T4239 T4240 det the,regulation
R3439 T4240 T4238 pobj regulation,to
R3440 T4241 T4240 prep of,regulation
R3441 T4242 T4243 compound cell,proliferation
R3442 T4243 T4241 pobj proliferation,of
R3443 T4244 T4243 cc and,proliferation
R3444 T4245 T4243 conj survival,proliferation
R3445 T4246 T4243 punct (,proliferation
R3446 T4247 T4240 acl reviewed,regulation
R3447 T4248 T4247 prep in,reviewed
R3448 T4249 T4248 pobj [,in
R3449 T4250 T4251 nummod 20,]
R3450 T4251 T4249 appos ],[
R3451 T4252 T4249 punct ),[
R3452 T4253 T4231 punct .,kinases
R3453 T4254 T4255 aux To,investigate
R3454 T4255 T4271 advcl investigate,cultured
R3455 T4256 T4257 det the,effect
R3456 T4257 T4255 dobj effect,investigate
R3457 T4258 T4263 dobj that,had
R3458 T4259 T4263 nsubj loss,had
R3459 T4260 T4259 prep of,loss
R3460 T4261 T4262 compound PKD,kinases
R3461 T4262 T4260 pobj kinases,of
R3462 T4263 T4257 relcl had,effect
R3463 T4264 T4263 prep on,had
R3464 T4265 T4267 compound B,survival
R3465 T4266 T4267 compound cell,survival
R3466 T4267 T4264 pobj survival,on
R3467 T4268 T4263 cc and/or,had
R3468 T4269 T4271 dobj proliferation,cultured
R3469 T4270 T4271 nsubj we,cultured
R3470 T4271 T4271 ROOT cultured,cultured
R3471 T4272 T4275 amod wild-type,cells
R3472 T4273 T4272 cc and,wild-type
R3473 T4274 T4272 conj PKD-null,wild-type
R3474 T4275 T4271 dobj cells,cultured
R3475 T4276 T4271 prep in,cultured
R3476 T4277 T4278 det the,presence
R3477 T4278 T4276 pobj presence,in
R3478 T4279 T4278 punct (,presence
R3479 T4280 T4300 nsubj PKD1/3,monitored
R3480 T4281 T4283 nummod −,−
R3481 T4282 T4283 compound /,−
R3482 T4283 T4300 dep −,monitored
R3483 T4284 T4283 punct :,−
R3484 T4285 T4287 nmod Flag-PKD3,ve
R3485 T4286 T4287 compound +,ve
R3486 T4287 T4283 appos ve,−
R3487 T4288 T4287 punct ),ve
R3488 T4289 T4287 cc or,ve
R3489 T4290 T4287 conj absence,ve
R3490 T4291 T4290 punct (,absence
R3491 T4292 T4295 nummod PKD1/3,−
R3492 T4293 T4295 nummod −,−
R3493 T4294 T4295 compound /,−
R3494 T4295 T4290 appos −,absence
R3495 T4296 T4295 punct ),−
R3496 T4297 T4290 prep of,absence
R3497 T4298 T4297 pobj doxycycline,of
R3498 T4299 T4290 cc and,absence
R3499 T4300 T4271 advcl monitored,cultured
R3500 T4301 T4302 amod exponential,growth
R3501 T4302 T4300 dobj growth,monitored
R3502 T4303 T4271 punct .,cultured
R3503 T4304 T4305 mark As,shown
R3504 T4305 T4311 advcl shown,−
R3505 T4306 T4305 prep in,shown
R3506 T4307 T4308 compound Fig.,2A
R3507 T4308 T4306 pobj 2A,in
R3508 T4309 T4311 punct ",",−
R3509 T4310 T4311 nsubj PKD1/3,−
R3510 T4311 T4311 ROOT −,−
R3511 T4312 T4314 nummod /,cells
R3512 T4313 T4314 compound −,cells
R3513 T4314 T4315 nsubj cells,proliferated
R3514 T4315 T4311 ccomp proliferated,−
R3515 T4316 T4315 advmod exponentially,proliferated
R3516 T4317 T4315 cc and,proliferated
R3517 T4318 T4324 nsubj re-expression,had
R3518 T4319 T4318 prep of,re-expression
R3519 T4320 T4319 pobj Flag-PKD3,of
R3520 T4321 T4318 prep in,re-expression
R3521 T4322 T4323 det these,cells
R3522 T4323 T4321 pobj cells,in
R3523 T4324 T4315 conj had,proliferated
R3524 T4325 T4326 det no,impact
R3525 T4326 T4324 dobj impact,had
R3526 T4327 T4326 prep on,impact
R3527 T4328 T4329 det the,rate
R3528 T4329 T4327 pobj rate,on
R3529 T4330 T4329 prep of,rate
R3530 T4331 T4330 pobj proliferation,of
R3531 T4332 T4311 punct .,−
R3532 T4333 T4347 advmod Furthermore,was
R3533 T4334 T4347 punct ",",was
R3534 T4335 T4336 det the,viability
R3535 T4336 T4347 nsubj viability,was
R3536 T4337 T4336 prep of,viability
R3537 T4338 T4343 nummod PKD1/3,cells
R3538 T4339 T4343 nummod −,cells
R3539 T4340 T4343 compound /,cells
R3540 T4341 T4343 compound −,cells
R3541 T4342 T4343 compound B,cells
R3542 T4343 T4337 pobj cells,of
R3543 T4344 T4336 prep during,viability
R3544 T4345 T4346 amod routine,culturing
R3545 T4346 T4344 pobj culturing,during
R3546 T4347 T4347 ROOT was,was
R3547 T4348 T4347 neg not,was
R3548 T4349 T4350 advmod significantly,different
R3549 T4350 T4347 acomp different,was
R3550 T4351 T4350 prep from,different
R3551 T4352 T4351 pobj that,from
R3552 T4353 T4352 prep of,that
R3553 T4354 T4356 amod wild-type,cells
R3554 T4355 T4356 compound B,cells
R3555 T4356 T4353 pobj cells,of
R3556 T4357 T4360 punct (,shown
R3557 T4358 T4360 nsubjpass data,shown
R3558 T4359 T4360 neg not,shown
R3559 T4360 T4347 conj shown,was
R3560 T4361 T4360 punct ),shown
R3561 T4362 T4347 punct .,was
R3562 T4363 T4365 nsubjpass It,noted
R3563 T4364 T4365 auxpass was,noted
R3564 T4365 T4365 ROOT noted,noted
R3565 T4366 T4377 mark that,was
R3566 T4367 T4370 det the,time
R3567 T4368 T4369 compound population,doubling
R3568 T4369 T4370 amod doubling,time
R3569 T4370 T4377 nsubj time,was
R3570 T4371 T4370 prep of,time
R3571 T4372 T4376 nummod PKD1/3,cells
R3572 T4373 T4376 nummod −,cells
R3573 T4374 T4376 compound /,cells
R3574 T4375 T4376 compound −,cells
R3575 T4376 T4371 pobj cells,of
R3576 T4377 T4365 ccomp was,noted
R3577 T4378 T4379 advmod slightly,slower
R3578 T4379 T4377 acomp slower,was
R3579 T4380 T4379 prep than,slower
R3580 T4381 T4380 pobj that,than
R3581 T4382 T4381 prep of,that
R3582 T4383 T4384 amod wild,type
R3583 T4384 T4382 pobj type,of
R3584 T4385 T4386 nummod DT40,cells
R3585 T4386 T4384 appos cells,type
R3586 T4387 T4386 punct (,cells
R3587 T4388 T4391 nummod 12.7,h
R3588 T4389 T4391 nmod ±,h
R3589 T4390 T4391 nummod 2.8,h
R3590 T4391 T4386 appos h,cells
R3591 T4392 T4391 prep versus,h
R3592 T4393 T4396 nummod 10.2,h
R3593 T4394 T4396 nmod ±,h
R3594 T4395 T4396 nummod 0.4,h
R3595 T4396 T4392 pobj h,versus
R3596 T4397 T4386 punct ),cells
R3597 T4398 T4365 cc but,noted
R3598 T4399 T4400 det the,failure
R3599 T4400 T4415 nsubj failure,suggests
R3600 T4401 T4400 prep of,failure
R3601 T4402 T4403 nummod PKD3,re-expression
R3602 T4403 T4401 pobj re-expression,of
R3603 T4404 T4405 aux to,modify
R3604 T4405 T4400 acl modify,failure
R3605 T4406 T4408 det the,rate
R3606 T4407 T4408 compound proliferation,rate
R3607 T4408 T4405 dobj rate,modify
R3608 T4409 T4408 prep of,rate
R3609 T4410 T4414 nummod PKD1/3,cells
R3610 T4411 T4414 nummod −,cells
R3611 T4412 T4414 compound /,cells
R3612 T4413 T4414 compound −,cells
R3613 T4414 T4409 pobj cells,of
R3614 T4415 T4365 conj suggests,noted
R3615 T4416 T4420 mark that,were
R3616 T4417 T4419 det these,differences
R3617 T4418 T4419 amod small,differences
R3618 T4419 T4420 nsubj differences,were
R3619 T4420 T4415 ccomp were,suggests
R3620 T4421 T4422 advmod most,likely
R3621 T4422 T4420 acomp likely,were
R3622 T4423 T4424 det the,result
R3623 T4424 T4420 attr result,were
R3624 T4425 T4424 prep of,result
R3625 T4426 T4427 amod clonal,variation
R3626 T4427 T4425 pobj variation,of
R3627 T4428 T4420 cc and,were
R3628 T4429 T4431 auxpass were,caused
R3629 T4430 T4431 neg not,caused
R3630 T4431 T4420 conj caused,were
R3631 T4432 T4431 advmod specifically,caused
R3632 T4433 T4431 agent by,caused
R3633 T4434 T4433 pobj loss,by
R3634 T4435 T4434 prep of,loss
R3635 T4436 T4437 compound PKD,enzymes
R3636 T4437 T4435 pobj enzymes,of
R3637 T4438 T4415 punct .,suggests
R3638 T4439 T4444 advmod Thus,are
R3639 T4440 T4444 punct ",",are
R3640 T4441 T4443 compound PKD,enzymes
R3641 T4442 T4443 compound family,enzymes
R3642 T4443 T4444 nsubj enzymes,are
R3643 T4444 T4444 ROOT are,are
R3644 T4445 T4444 neg not,are
R3645 T4446 T4444 acomp essential,are
R3646 T4447 T4446 prep for,essential
R3647 T4448 T4447 pcomp regulating,for
R3648 T4449 T4450 amod basal,survival
R3649 T4450 T4448 dobj survival,regulating
R3650 T4451 T4450 cc and,survival
R3651 T4452 T4450 conj proliferation,survival
R3652 T4453 T4452 prep of,proliferation
R3653 T4454 T4455 compound DT40,B
R3654 T4455 T4456 compound B,cells
R3655 T4456 T4453 pobj cells,of
R3656 T4457 T4444 punct .,are
R3657 T4458 T4459 compound PKD,enzymes
R3658 T4459 T4469 nsubj enzymes,linked
R3659 T4460 T4459 punct ",",enzymes
R3660 T4461 T4462 advmod specifically,PKD1
R3661 T4462 T4459 appos PKD1,enzymes
R3662 T4463 T4462 cc and,PKD1
R3663 T4464 T4462 conj PKD2,PKD1
R3664 T4465 T4469 punct ",",linked
R3665 T4466 T4469 aux have,linked
R3666 T4467 T4469 advmod previously,linked
R3667 T4468 T4469 auxpass been,linked
R3668 T4469 T4469 ROOT linked,linked
R3669 T4470 T4469 prep to,linked
R3670 T4471 T4473 det a,role
R3671 T4472 T4473 amod protective,role
R3672 T4473 T4470 pobj role,to
R3673 T4474 T4473 prep against,role
R3674 T4475 T4477 amod oxidative,injury
R3675 T4476 T4477 amod stress-induced,injury
R3676 T4477 T4486 nmod injury,lines
R3677 T4478 T4477 prep in,injury
R3678 T4479 T4480 compound 3T3,fibroblast
R3679 T4480 T4478 pobj fibroblast,in
R3680 T4481 T4480 punct ",",fibroblast
R3681 T4482 T4480 conj HeLa,fibroblast
R3682 T4483 T4482 cc and,HeLa
R3683 T4484 T4486 amod epithelial,lines
R3684 T4485 T4486 compound cell,lines
R3685 T4486 T4474 pobj lines,against
R3686 T4487 T4488 compound [,"17,30"
R3687 T4488 T4486 appos "17,30",lines
R3688 T4489 T4490 nummod 32,]
R3689 T4490 T4486 appos ],lines
R3690 T4491 T4469 punct .,linked
R3691 T4492 T4494 nsubj We,addressed
R3692 T4493 T4494 advmod therefore,addressed
R3693 T4494 T4494 ROOT addressed,addressed
R3694 T4495 T4496 det the,role
R3695 T4496 T4494 dobj role,addressed
R3696 T4497 T4496 prep of,role
R3697 T4498 T4499 compound PKD,family
R3698 T4499 T4500 compound family,kinases
R3699 T4500 T4497 pobj kinases,of
R3700 T4501 T4496 prep in,role
R3701 T4502 T4501 pcomp regulating,in
R3702 T4503 T4504 compound B,cell
R3703 T4504 T4505 compound cell,survival
R3704 T4505 T4502 dobj survival,regulating
R3705 T4506 T4502 prep in,regulating
R3706 T4507 T4506 pobj response,in
R3707 T4508 T4507 prep to,response
R3708 T4509 T4510 amod oxidative,stress
R3709 T4510 T4508 pobj stress,to
R3710 T4511 T4510 cc and,stress
R3711 T4512 T4514 amod other,stimuli
R3712 T4513 T4514 compound stress,stimuli
R3713 T4514 T4510 conj stimuli,stress
R3714 T4515 T4494 punct .,addressed
R3715 T4516 T4517 mark As,shown
R3716 T4517 T4526 advcl shown,had
R3717 T4518 T4517 prep in,shown
R3718 T4519 T4520 compound Fig.,2B
R3719 T4520 T4518 pobj 2B,in
R3720 T4521 T4520 punct ",",2B
R3721 T4522 T4520 appos loss,2B
R3722 T4523 T4522 prep of,loss
R3723 T4524 T4525 nummod PKD1/3,expression
R3724 T4525 T4523 pobj expression,of
R3725 T4526 T4526 ROOT had,had
R3726 T4527 T4529 det no,impact
R3727 T4528 T4529 amod significant,impact
R3728 T4529 T4526 dobj impact,had
R3729 T4530 T4529 prep on,impact
R3730 T4531 T4532 det the,survival
R3731 T4532 T4530 pobj survival,on
R3732 T4533 T4532 prep of,survival
R3733 T4534 T4535 compound DT40,B
R3734 T4535 T4536 compound B,cells
R3735 T4536 T4533 pobj cells,of
R3736 T4537 T4526 prep in,had
R3737 T4538 T4537 pobj response,in
R3738 T4539 T4538 prep to,response
R3739 T4540 T4542 amod mitochondrial,stimuli
R3740 T4541 T4542 compound stress,stimuli
R3741 T4542 T4539 pobj stimuli,to
R3742 T4543 T4542 punct (,stimuli
R3743 T4544 T4542 appos H2O2,stimuli
R3744 T4545 T4544 cc or,H2O2
R3745 T4546 T4547 compound serum,deprivation
R3746 T4547 T4544 conj deprivation,H2O2
R3747 T4548 T4542 punct ),stimuli
R3748 T4549 T4542 punct ;,stimuli
R3749 T4550 T4552 amod DNA,agents
R3750 T4551 T4552 amod damaging,agents
R3751 T4552 T4542 conj agents,stimuli
R3752 T4553 T4552 punct (,agents
R3753 T4554 T4552 appos etoposide,agents
R3754 T4555 T4554 cc or,etoposide
R3755 T4556 T4554 conj doxorubicin,etoposide
R3756 T4557 T4552 punct ),agents
R3757 T4558 T4526 punct ;,had
R3758 T4559 T4561 compound ER,stress
R3759 T4560 T4561 compound pathway,stress
R3760 T4561 T4570 nsubj stress,following
R3761 T4562 T4561 amod due,stress
R3762 T4563 T4562 pcomp to,due
R3763 T4564 T4565 compound calcium,overload
R3764 T4565 T4562 pobj overload,due
R3765 T4566 T4567 punct (,thapsigargin
R3766 T4567 T4565 appos thapsigargin,overload
R3767 T4568 T4567 punct ),thapsigargin
R3768 T4569 T4565 cc or,overload
R3769 T4570 T4526 advcl following,had
R3770 T4571 T4572 amod prolonged,treatment
R3771 T4572 T4570 dobj treatment,following
R3772 T4573 T4572 prep with,treatment
R3773 T4574 T4575 compound phorbol,esters
R3774 T4575 T4573 pobj esters,with
R3775 T4576 T4575 cc or,esters
R3776 T4577 T4578 compound Trichostatin,A
R3777 T4578 T4575 conj A,esters
R3778 T4579 T4578 punct ",",A
R3779 T4580 T4581 det an,inhibitor
R3780 T4581 T4578 appos inhibitor,A
R3781 T4582 T4581 prep of,inhibitor
R3782 T4583 T4585 compound class,HDACs
R3783 T4584 T4585 compound I/II,HDACs
R3784 T4585 T4582 pobj HDACs,of
R3785 T4586 T4526 punct .,had
R3786 T4587 T4593 advmod Thus,play
R3787 T4588 T4593 punct ",",play
R3788 T4589 T4590 compound PKD,kinases
R3789 T4590 T4593 nsubj kinases,play
R3790 T4591 T4593 aux do,play
R3791 T4592 T4593 neg not,play
R3792 T4593 T4593 ROOT play,play
R3793 T4594 T4596 det an,role
R3794 T4595 T4596 amod essential,role
R3795 T4596 T4593 dobj role,play
R3796 T4597 T4593 prep in,play
R3797 T4598 T4597 pcomp regulating,in
R3798 T4599 T4600 compound B,cell
R3799 T4600 T4601 compound cell,survival
R3800 T4601 T4598 dobj survival,regulating
R3801 T4602 T4598 prep in,regulating
R3802 T4603 T4602 pobj response,in
R3803 T4604 T4603 prep to,response
R3804 T4605 T4606 det a,range
R3805 T4606 T4604 pobj range,to
R3806 T4607 T4606 prep of,range
R3807 T4608 T4610 amod different,stimuli
R3808 T4609 T4610 compound stress,stimuli
R3809 T4610 T4607 pobj stimuli,of
R3810 T4611 T4593 punct .,play