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PMC:1359074 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T573 0-4 NNP denotes Sox6
T574 5-13 RB denotes Directly
T575 14-22 NNPS denotes Silences
T576 23-30 NNP denotes Epsilon
T577 31-37 NNP denotes Globin
T578 38-48 NNP denotes Expression
T579 49-51 IN denotes in
T580 52-62 NNP denotes Definitive
T581 63-77 NNP denotes Erythropoiesis
T582 127-131 NNP denotes Sox6
T583 132-134 VBZ denotes is
T584 135-136 DT denotes a
T585 137-143 NN denotes member
T586 144-146 IN denotes of
T587 147-150 DT denotes the
T588 151-154 NNPS denotes Sox
T589 155-168 NN denotes transcription
T590 169-175 NN denotes factor
T591 176-182 NN denotes family
T592 183-187 WDT denotes that
T593 188-190 VBZ denotes is
T594 191-198 VBN denotes defined
T595 199-201 IN denotes by
T596 202-205 DT denotes the
T597 206-215 JJ denotes conserved
T598 216-220 JJ denotes high
T599 221-229 NN denotes mobility
T600 230-235 NN denotes group
T601 236-237 -LRB- denotes (
T602 237-240 NNP denotes HMG
T603 240-241 -RRB- denotes )
T604 242-245 NNP denotes DNA
T605 246-253 JJ denotes binding
T606 254-260 NN denotes domain
T607 260-261 , denotes ,
T608 262-267 JJ denotes first
T609 268-277 VBN denotes described
T610 278-280 IN denotes in
T611 281-284 DT denotes the
T612 285-291 NN denotes testis
T613 292-303 VBG denotes determining
T614 304-308 NN denotes gene
T615 308-309 , denotes ,
T616 310-313 NNP denotes Sry
T617 313-314 . denotes .
T618 315-323 JJ denotes Previous
T619 324-331 NNS denotes studies
T620 332-336 VBP denotes have
T621 337-346 VBN denotes suggested
T622 347-351 IN denotes that
T623 352-356 JJ denotes Sox6
T624 357-362 NNS denotes plays
T625 363-364 DT denotes a
T626 365-369 NN denotes role
T627 370-372 IN denotes in
T628 373-376 DT denotes the
T629 377-388 NN denotes development
T630 389-391 IN denotes of
T631 392-395 DT denotes the
T632 396-403 JJ denotes central
T633 404-411 JJ denotes nervous
T634 412-418 NN denotes system
T635 418-419 , denotes ,
T636 420-429 NN denotes cartilage
T637 429-430 , denotes ,
T638 431-434 CC denotes and
T639 435-441 NN denotes muscle
T640 441-442 . denotes .
T641 443-445 IN denotes In
T642 446-449 DT denotes the
T643 450-464 JJ denotes Sox6-deficient
T644 465-470 NN denotes mouse
T645 470-471 , denotes ,
T646 472-477 NNP denotes p100H
T647 477-478 , denotes ,
T648 479-481 JJ denotes ɛy
T649 482-488 NN denotes globin
T650 489-491 VBZ denotes is
T651 492-504 RB denotes persistently
T652 505-514 VBN denotes expressed
T653 514-515 , denotes ,
T654 516-519 CC denotes and
T655 520-529 VBD denotes increased
T656 530-537 NNS denotes numbers
T657 538-540 IN denotes of
T658 541-550 JJ denotes nucleated
T659 551-554 JJ denotes red
T660 555-560 NNS denotes cells
T661 561-564 VBP denotes are
T662 565-572 JJ denotes present
T663 573-575 IN denotes in
T664 576-579 DT denotes the
T665 580-585 JJ denotes fetal
T666 586-597 NN denotes circulation
T667 597-598 . denotes .
T668 599-611 NNP denotes Transfection
T669 612-618 NNS denotes assays
T670 619-621 IN denotes in
T671 622-627 NNP denotes GM979
T672 628-629 -LRB- denotes (
T673 629-644 JJ denotes erythroleukemic
T674 644-645 -RRB- denotes )
T675 646-651 NNS denotes cells
T676 652-658 VBP denotes define
T677 659-660 DT denotes a
T678 661-663 CD denotes 36
T679 664-668 JJ denotes base
T680 669-673 NN denotes pair
T681 674-680 NN denotes region
T682 681-683 IN denotes of
T683 684-687 DT denotes the
T684 688-690 JJ denotes ɛy
T685 691-699 JJ denotes proximal
T686 700-708 NN denotes promoter
T687 709-713 WDT denotes that
T688 714-716 VBZ denotes is
T689 717-725 JJ denotes critical
T690 726-729 IN denotes for
T691 730-734 JJ denotes Sox6
T692 735-743 VBN denotes mediated
T693 744-754 NN denotes repression
T694 754-755 . denotes .
T695 756-771 JJ denotes Electrophoretic
T696 772-780 NN denotes mobility
T697 781-786 NN denotes shift
T698 787-792 NN denotes assay
T699 793-794 -LRB- denotes (
T700 794-798 NNP denotes EMSA
T701 798-799 -RRB- denotes )
T702 800-803 CC denotes and
T703 804-813 NN denotes chromatin
T704 814-833 NN denotes immunoprecipitation
T705 834-835 -LRB- denotes (
T706 835-839 NNP denotes ChIP
T707 839-840 -RRB- denotes )
T708 841-847 NNS denotes assays
T709 848-859 VBP denotes demonstrate
T710 860-864 IN denotes that
T711 865-869 JJ denotes Sox6
T712 870-874 NNS denotes acts
T713 875-877 IN denotes as
T714 878-879 DT denotes a
T715 880-889 NN denotes repressor
T716 890-892 IN denotes by
T717 893-901 RB denotes directly
T718 902-909 JJ denotes binding
T719 910-912 TO denotes to
T720 913-916 DT denotes the
T721 917-919 JJ denotes ɛy
T722 920-928 NN denotes promoter
T723 928-929 . denotes .
T724 930-933 DT denotes The
T725 934-940 JJ denotes normal
T726 941-951 NN denotes expression
T727 952-954 IN denotes of
T728 955-959 NNP denotes Sox6
T729 960-962 IN denotes in
T730 963-972 JJ denotes wild-type
T731 973-978 JJ denotes fetal
T732 979-984 NN denotes liver
T733 985-988 CC denotes and
T734 989-992 DT denotes the
T735 993-1000 JJ denotes ectopic
T736 1001-1011 NN denotes expression
T737 1012-1014 IN denotes of
T738 1015-1017 NN denotes ɛy
T739 1018-1020 IN denotes in
T740 1021-1026 JJ denotes p100H
T741 1027-1037 JJ denotes homozygous
T742 1038-1043 JJ denotes fetal
T743 1044-1049 NN denotes liver
T744 1050-1061 VBP denotes demonstrate
T745 1062-1066 IN denotes that
T746 1067-1071 JJ denotes Sox6
T747 1072-1081 NNS denotes functions
T748 1082-1084 IN denotes in
T749 1085-1095 JJ denotes definitive
T750 1096-1110 NNS denotes erythropoiesis
T751 1110-1111 . denotes .
T752 1112-1115 DT denotes The
T753 1116-1123 JJ denotes present
T754 1124-1129 NN denotes study
T755 1130-1135 VBZ denotes shows
T756 1136-1140 IN denotes that
T757 1141-1145 NNP denotes Sox6
T758 1146-1148 VBZ denotes is
T759 1149-1157 VBN denotes required
T760 1158-1161 IN denotes for
T761 1162-1171 VBG denotes silencing
T762 1172-1174 IN denotes of
T763 1175-1177 JJ denotes ɛy
T764 1178-1184 NN denotes globin
T765 1185-1187 IN denotes in
T766 1188-1198 JJ denotes definitive
T767 1199-1213 NNS denotes erythropoiesis
T768 1214-1217 CC denotes and
T769 1218-1226 VBZ denotes suggests
T770 1227-1228 DT denotes a
T771 1229-1233 NN denotes role
T772 1234-1237 IN denotes for
T773 1238-1242 NNP denotes Sox6
T774 1243-1245 IN denotes in
T775 1246-1255 JJ denotes erythroid
T776 1256-1260 NN denotes cell
T777 1261-1271 NN denotes maturation
T778 1271-1272 . denotes .
T779 1273-1277 RB denotes Thus
T780 1277-1278 , denotes ,
T781 1279-1283 JJ denotes Sox6
T782 1284-1294 NN denotes regulation
T783 1295-1297 IN denotes of
T784 1298-1300 JJ denotes ɛy
T785 1301-1307 NN denotes globin
T786 1308-1313 MD denotes might
T787 1314-1321 VB denotes provide
T788 1322-1323 DT denotes a
T789 1324-1329 NN denotes novel
T790 1330-1343 JJ denotes therapeutical
T791 1344-1350 NN denotes target
T792 1351-1353 IN denotes in
T793 1354-1357 DT denotes the
T794 1358-1367 NN denotes treatment
T795 1368-1370 IN denotes of
T796 1371-1389 NNS denotes hemoglobinopathies
T797 1390-1394 JJ denotes such
T798 1395-1397 IN denotes as
T799 1398-1404 JJ denotes sickle
T800 1405-1409 NN denotes cell
T801 1410-1416 NN denotes anemia
T802 1417-1420 CC denotes and
T803 1421-1432 NN denotes thalassemia
T804 1432-1433 . denotes .
T2913 2855-2858 NNP denotes Sry
T2914 2859-2863 NN denotes type
T2915 2864-2867 NNP denotes HMG
T2916 2868-2871 NN denotes box
T2917 2872-2873 -LRB- denotes (
T2918 2873-2877 NNP denotes Sox6
T2919 2877-2878 -RRB- denotes )
T2920 2879-2881 VBZ denotes is
T2921 2882-2883 DT denotes a
T2922 2884-2890 NN denotes member
T2923 2891-2893 IN denotes of
T2924 2894-2897 DT denotes the
T2925 2898-2901 NNPS denotes Sox
T2926 2902-2915 NN denotes transcription
T2927 2916-2922 NN denotes factor
T2928 2923-2929 NN denotes family
T2929 2930-2943 VBN denotes characterized
T2930 2944-2946 IN denotes by
T2931 2947-2950 DT denotes the
T2932 2951-2960 JJ denotes conserved
T2933 2961-2965 JJ denotes high
T2934 2966-2974 NN denotes mobility
T2935 2975-2980 NN denotes group
T2936 2981-2982 -LRB- denotes (
T2937 2982-2985 NNP denotes HMG
T2938 2985-2986 -RRB- denotes )
T2939 2987-2993 NN denotes domain
T2940 2993-2994 , denotes ,
T2941 2995-3005 VBG denotes consisting
T2942 3006-3008 IN denotes of
T2943 3009-3011 CD denotes 79
T2944 3012-3017 JJ denotes amino
T2945 3018-3023 NNS denotes acids
T2946 3024-3032 VBN denotes involved
T2947 3033-3035 IN denotes in
T2948 3036-3039 NNP denotes DNA
T2949 3040-3051 NN denotes recognition
T2950 3052-3055 CC denotes and
T2951 3056-3063 JJ denotes binding
T2952 3064-3065 NN denotes [
T2953 3065-3066 CD denotes 1
T2954 3066-3067 NNP denotes ]
T2955 3067-3068 . denotes .
T2956 3069-3072 NNP denotes Sox
T2957 3073-3086 NN denotes transcription
T2958 3087-3094 NNS denotes factors
T2959 3095-3099 NN denotes bind
T2960 3100-3102 TO denotes to
T2961 3103-3106 DT denotes the
T2962 3107-3112 JJ denotes minor
T2963 3113-3119 NN denotes groove
T2964 3120-3122 IN denotes of
T2965 3123-3126 NNP denotes DNA
T2966 3127-3130 CC denotes and
T2967 3131-3136 VB denotes cause
T2968 3137-3138 DT denotes a
T2969 3139-3141 CD denotes 70
T2970 3141-3142 NN denotes °
T2971 3143-3145 CD denotes 85
T2972 3145-3146 NN denotes °
T2973 3147-3151 VB denotes bend
T2974 3152-3154 IN denotes of
T2975 3155-3158 DT denotes the
T2976 3159-3162 NN denotes DNA
T2977 3163-3167 WDT denotes that
T2978 3168-3173 VBZ denotes leads
T2979 3174-3176 TO denotes to
T2980 3177-3182 JJ denotes local
T2981 3183-3197 JJ denotes conformational
T2982 3198-3205 NNS denotes changes
T2983 3206-3207 NNP denotes [
T2984 3207-3210 CD denotes 2,3
T2985 3210-3211 NNP denotes ]
T2986 3211-3212 , denotes ,
T2987 3213-3218 IN denotes while
T2988 3219-3223 RBS denotes most
T2989 3224-3229 JJ denotes other
T2990 3230-3243 NN denotes transcription
T2991 3244-3251 NNS denotes factors
T2992 3252-3258 VBP denotes target
T2993 3259-3262 DT denotes the
T2994 3263-3268 JJ denotes major
T2995 3269-3275 NN denotes groove
T2996 3276-3278 IN denotes of
T2997 3279-3282 NNP denotes DNA
T2998 3283-3284 NNP denotes [
T2999 3284-3285 CD denotes 4
T3000 3285-3286 NNP denotes ]
T3001 3286-3287 . denotes .
T3002 3288-3297 RB denotes Therefore
T3003 3297-3298 , denotes ,
T3004 3299-3302 NNP denotes Sox
T3005 3303-3311 NNS denotes proteins
T3006 3312-3315 MD denotes may
T3007 3316-3323 VB denotes perform
T3008 3324-3328 NN denotes part
T3009 3329-3331 IN denotes of
T3010 3332-3337 PRP$ denotes their
T3011 3338-3346 NN denotes function
T3012 3347-3349 IN denotes as
T3013 3350-3363 JJ denotes architectural
T3014 3364-3372 NNS denotes proteins
T3015 3373-3375 IN denotes by
T3016 3376-3386 VBG denotes organizing
T3017 3387-3392 JJ denotes local
T3018 3393-3402 NN denotes chromatin
T3019 3403-3412 NN denotes structure
T3020 3413-3416 CC denotes and
T3021 3417-3427 VBG denotes assembling
T3022 3428-3433 JJ denotes other
T3023 3434-3443 JJ denotes DNA-bound
T3024 3444-3457 NN denotes transcription
T3025 3458-3465 NNS denotes factors
T3026 3466-3470 IN denotes into
T3027 3471-3483 RB denotes biologically
T3028 3484-3490 JJ denotes active
T3029 3490-3491 , denotes ,
T3030 3492-3502 RB denotes sterically
T3031 3503-3510 VBN denotes defined
T3032 3511-3523 NN denotes multiprotein
T3033 3524-3533 NNS denotes complexes
T3034 3533-3534 . denotes .
T3035 3535-3539 NNP denotes Sox6
T3036 3540-3543 VBZ denotes has
T3037 3544-3548 VBN denotes been
T3038 3549-3557 VBN denotes reported
T3039 3558-3560 TO denotes to
T3040 3561-3563 VB denotes be
T3041 3564-3568 JJ denotes able
T3042 3569-3571 TO denotes to
T3043 3572-3575 VB denotes act
T3044 3576-3578 IN denotes as
T3045 3579-3585 DT denotes either
T3046 3586-3588 DT denotes an
T3047 3589-3598 NN denotes activator
T3048 3599-3601 CC denotes or
T3049 3602-3603 DT denotes a
T3050 3604-3613 NN denotes repressor
T3051 3613-3614 , denotes ,
T3052 3615-3624 VBG denotes depending
T3053 3625-3627 IN denotes on
T3054 3628-3631 PRP$ denotes its
T3055 3632-3643 NNS denotes interactors
T3056 3644-3647 CC denotes and
T3057 3648-3651 PRP$ denotes its
T3058 3652-3658 NN denotes target
T3059 3659-3667 NN denotes promoter
T3060 3668-3675 NN denotes context
T3061 3676-3677 NNP denotes [
T3062 3677-3680 CD denotes 5,6
T3063 3680-3681 NNP denotes ]
T3064 3681-3682 . denotes .
T3065 3683-3695 RB denotes Intriguingly
T3066 3695-3696 , denotes ,
T3067 3697-3701 NNP denotes Sox6
T3068 3702-3705 VBZ denotes has
T3069 3706-3710 RB denotes also
T3070 3711-3715 VBN denotes been
T3071 3716-3721 VBN denotes shown
T3072 3722-3724 TO denotes to
T3073 3725-3728 VB denotes act
T3074 3729-3731 IN denotes as
T3075 3732-3733 DT denotes a
T3076 3734-3741 JJ denotes general
T3077 3742-3750 NN denotes splicing
T3078 3751-3757 NN denotes factor
T3079 3758-3762 WDT denotes that
T3080 3763-3775 VBZ denotes participates
T3081 3776-3778 IN denotes in
T3082 3779-3787 JJ denotes pre-mRNA
T3083 3788-3796 NN denotes splicing
T3084 3797-3798 NN denotes [
T3085 3798-3799 CD denotes 7
T3086 3799-3800 NNP denotes ]
T3087 3800-3801 . denotes .
T3088 3802-3811 NN denotes Depletion
T3089 3812-3814 IN denotes of
T3090 3815-3819 NNP denotes Sox6
T3091 3820-3822 IN denotes in
T3092 3823-3827 NNP denotes HeLa
T3093 3828-3832 NN denotes cell
T3094 3833-3841 VBZ denotes extracts
T3095 3842-3849 VBN denotes blocked
T3096 3850-3858 NN denotes splicing
T3097 3859-3861 IN denotes of
T3098 3862-3870 JJ denotes multiple
T3099 3871-3881 NNS denotes substrates
T3100 3881-3882 , denotes ,
T3101 3883-3886 CC denotes and
T3102 3887-3897 NN denotes expression
T3103 3898-3900 IN denotes of
T3104 3901-3904 DT denotes the
T3105 3905-3908 NNP denotes HMG
T3106 3909-3915 NN denotes domain
T3107 3916-3918 IN denotes of
T3108 3919-3925 DT denotes either
T3109 3926-3930 NNP denotes Sox6
T3110 3930-3931 , denotes ,
T3111 3932-3936 NNP denotes Sox9
T3112 3936-3937 , denotes ,
T3113 3938-3940 CC denotes or
T3114 3941-3944 NNP denotes Sry
T3115 3945-3947 IN denotes in
T3116 3948-3951 DT denotes the
T3117 3952-3960 NNS denotes extracts
T3118 3961-3969 VBD denotes restored
T3119 3970-3978 NN denotes splicing
T3120 3978-3979 , denotes ,
T3121 3980-3990 VBG denotes indicating
T3122 3991-4001 JJ denotes functional
T3123 4002-4009 VBP denotes overlap
T3124 4010-4012 IN denotes of
T3125 4013-4018 DT denotes these
T3126 4019-4027 NNS denotes proteins
T3127 4028-4029 VBP denotes [
T3128 4029-4030 CD denotes 7
T3129 4030-4031 NNP denotes ]
T3130 4031-4032 . denotes .
T3131 4033-4043 RB denotes Regardless
T3132 4044-4046 IN denotes of
T3133 4047-4050 WRB denotes how
T3134 4051-4055 JJ denotes Sox6
T3135 4056-4065 NNS denotes functions
T3136 4066-4068 IN denotes in
T3137 4069-4079 VBG denotes regulating
T3138 4080-4084 NN denotes gene
T3139 4085-4095 NN denotes expression
T3140 4095-4096 , denotes ,
T3141 4097-4105 JJ denotes previous
T3142 4106-4113 NNS denotes studies
T3143 4114-4118 VBP denotes have
T3144 4119-4131 VBN denotes demonstrated
T3145 4132-4136 IN denotes that
T3146 4137-4141 NNP denotes Sox6
T3147 4142-4144 VBZ denotes is
T3148 4145-4147 DT denotes an
T3149 4148-4157 JJ denotes important
T3150 4158-4168 JJ denotes regulatory
T3151 4169-4177 NN denotes molecule
T3152 4178-4182 WDT denotes that
T3153 4183-4188 VBZ denotes plays
T3154 4189-4190 DT denotes a
T3155 4191-4195 NN denotes role
T3156 4196-4198 IN denotes in
T3157 4199-4202 DT denotes the
T3158 4203-4214 NN denotes development
T3159 4215-4217 IN denotes of
T3160 4218-4221 DT denotes the
T3161 4222-4229 JJ denotes central
T3162 4230-4237 JJ denotes nervous
T3163 4238-4244 NN denotes system
T3164 4245-4246 NN denotes [
T3165 4246-4247 CD denotes 8
T3166 4248-4250 CD denotes 11
T3167 4250-4251 NNP denotes ]
T3168 4251-4252 , denotes ,
T3169 4253-4262 NN denotes cartilage
T3170 4263-4264 NNP denotes [
T3171 4264-4271 CD denotes 6,12,13
T3172 4271-4272 NNP denotes ]
T3173 4272-4273 , denotes ,
T3174 4274-4277 CC denotes and
T3175 4278-4284 NN denotes muscle
T3176 4285-4286 NNP denotes [
T3177 4286-4291 CD denotes 14,15
T3178 4291-4292 NNP denotes ]
T3179 4292-4293 . denotes .
T3180 4294-4295 DT denotes A
T3181 4296-4305 JJ denotes Sox6-null
T3182 4306-4312 JJ denotes mutant
T3183 4313-4318 NN denotes mouse
T3184 4319-4320 -LRB- denotes (
T3185 4320-4325 JJ denotes p100H
T3186 4325-4326 -RRB- denotes )
T3187 4327-4330 VBZ denotes has
T3188 4331-4341 RB denotes previously
T3189 4342-4346 VBN denotes been
T3190 4347-4357 VBN denotes identified
T3191 4358-4360 IN denotes in
T3192 4361-4364 PRP$ denotes our
T3193 4365-4375 NN denotes laboratory
T3194 4376-4377 NNP denotes [
T3195 4377-4379 CD denotes 14
T3196 4379-4380 NNP denotes ]
T3197 4380-4381 . denotes .
T3198 4382-4386 NN denotes Mice
T3199 4387-4397 NNS denotes homozygous
T3200 4398-4401 IN denotes for
T3201 4402-4407 JJ denotes p100H
T3202 4408-4412 NN denotes show
T3203 4413-4420 VBN denotes delayed
T3204 4421-4427 NN denotes growth
T3205 4427-4428 , denotes ,
T3206 4429-4436 VB denotes develop
T3207 4437-4445 NN denotes myopathy
T3208 4446-4449 CC denotes and
T3209 4450-4468 JJ denotes arterioventricular
T3210 4469-4474 NN denotes heart
T3211 4475-4480 NN denotes block
T3212 4480-4481 , denotes ,
T3213 4482-4485 CC denotes and
T3214 4486-4489 VB denotes die
T3215 4490-4496 IN denotes within
T3216 4497-4498 CD denotes 2
T3217 4499-4501 NN denotes wk
T3218 4502-4507 IN denotes after
T3219 4508-4513 NN denotes birth
T3220 4514-4515 NNP denotes [
T3221 4515-4517 CD denotes 14
T3222 4517-4518 NNP denotes ]
T3223 4518-4519 . denotes .
T3224 4520-4523 DT denotes The
T3225 4524-4529 JJ denotes p100H
T3226 4530-4536 JJ denotes mutant
T3227 4537-4543 NN denotes allele
T3228 4544-4546 VBZ denotes is
T3229 4547-4557 VBN denotes associated
T3230 4558-4562 IN denotes with
T3231 4563-4564 DT denotes a
T3232 4565-4575 NN denotes Chromosome
T3233 4576-4577 CD denotes 7
T3234 4578-4587 NN denotes inversion
T3235 4588-4592 WDT denotes that
T3236 4593-4601 VBZ denotes disrupts
T3237 4602-4606 CC denotes both
T3238 4607-4610 DT denotes the
T3239 4611-4612 NN denotes p
T3240 4613-4617 NN denotes gene
T3241 4618-4621 CC denotes and
T3242 4622-4625 DT denotes the
T3243 4626-4630 NNP denotes Sox6
T3244 4631-4635 NN denotes gene
T3245 4636-4637 -LRB- denotes (
T3246 4637-4640 CC denotes and
T3247 4641-4643 DT denotes no
T3248 4644-4649 JJ denotes other
T3249 4650-4654 NN denotes gene
T3250 4655-4661 IN denotes within
T3251 4662-4668 CD denotes 50,000
T3252 4669-4680 NNS denotes nucleotides
T3253 4681-4683 IN denotes of
T3254 4684-4687 DT denotes the
T3255 4688-4699 JJ denotes chromosomal
T3256 4700-4711 NNS denotes breakpoints
T3257 4711-4712 -RRB- denotes )
T3258 4713-4714 NNP denotes [
T3259 4714-4716 CD denotes 14
T3260 4716-4717 NNP denotes ]
T3261 4717-4718 . denotes .
T3262 4719-4726 IN denotes Because
T3263 4727-4730 DT denotes the
T3264 4731-4732 NN denotes p
T3265 4733-4737 NN denotes gene
T3266 4738-4747 NNS denotes functions
T3267 4748-4754 RB denotes solely
T3268 4755-4757 IN denotes in
T3269 4758-4770 NN denotes pigmentation
T3270 4771-4772 NNP denotes [
T3271 4772-4774 CD denotes 16
T3272 4774-4775 NNP denotes ]
T3273 4775-4776 , denotes ,
T3274 4777-4780 DT denotes the
T3275 4781-4785 NNP denotes Sox6
T3276 4786-4799 NN denotes transcription
T3277 4800-4806 NN denotes factor
T3278 4807-4809 VBZ denotes is
T3279 4810-4820 VBN denotes implicated
T3280 4821-4823 IN denotes in
T3281 4824-4827 DT denotes all
T3282 4828-4833 JJ denotes other
T3283 4834-4844 NNS denotes phenotypes
T3284 4844-4845 . denotes .
T3285 4846-4851 IN denotes Among
T3286 4852-4855 DT denotes the
T3287 4856-4859 NNP denotes HMG
T3288 4860-4863 NN denotes box
T3289 4864-4872 NNS denotes proteins
T3290 4873-4882 RB denotes distantly
T3291 4883-4890 VBN denotes related
T3292 4891-4893 TO denotes to
T3293 4894-4897 NNP denotes Sry
T3294 4898-4899 -LRB- denotes (
T3295 4899-4902 DT denotes the
T3296 4903-4908 JJ denotes first
T3297 4909-4915 NN denotes member
T3298 4916-4926 VBN denotes identified
T3299 4927-4929 IN denotes of
T3300 4930-4933 DT denotes the
T3301 4934-4937 NNPS denotes Sox
T3302 4938-4951 NN denotes transcription
T3303 4952-4958 NN denotes factor
T3304 4959-4965 NN denotes family
T3305 4965-4966 -RRB- denotes )
T3306 4967-4971 WDT denotes that
T3307 4972-4981 RB denotes similarly
T3308 4982-4986 NN denotes bind
T3309 4987-4989 TO denotes to
T3310 4990-4993 DT denotes the
T3311 4994-4999 JJ denotes minor
T3312 5000-5006 NN denotes groove
T3313 5007-5010 CC denotes and
T3314 5011-5015 VB denotes bend
T3315 5016-5019 NNP denotes DNA
T3316 5019-5020 , denotes ,
T3317 5021-5024 CC denotes but
T3318 5025-5032 IN denotes without
T3319 5033-5041 NN denotes sequence
T3320 5042-5053 NN denotes specificity
T3321 5053-5054 , denotes ,
T3322 5055-5058 VBP denotes are
T3323 5059-5062 DT denotes the
T3324 5063-5075 RB denotes ubiquitously
T3325 5076-5085 VBN denotes expressed
T3326 5086-5090 NNP denotes HMG1
T3327 5091-5094 CC denotes and
T3328 5095-5099 NNP denotes HMG2
T3329 5100-5108 NNS denotes proteins
T3330 5109-5110 NNP denotes [
T3331 5110-5112 CD denotes 17
T3332 5112-5113 NNP denotes ]
T3333 5113-5114 . denotes .
T3334 5115-5125 NNP denotes Modulation
T3335 5126-5128 IN denotes of
T3336 5129-5132 NNP denotes DNA
T3337 5133-5142 NN denotes structure
T3338 5143-5145 IN denotes by
T3339 5146-5151 DT denotes these
T3340 5152-5155 CC denotes and
T3341 5156-5161 JJ denotes other
T3342 5162-5165 NNP denotes HMG
T3343 5166-5174 NNS denotes proteins
T3344 5175-5178 MD denotes can
T3345 5179-5186 VB denotes mediate
T3346 5187-5197 JJ denotes long-range
T3347 5198-5206 NN denotes enhancer
T3348 5207-5215 NN denotes function
T3349 5216-5218 IN denotes on
T3350 5219-5223 DT denotes both
T3351 5224-5227 NNP denotes DNA
T3352 5228-5231 CC denotes and
T3353 5232-5251 JJ denotes chromatin-assembled
T3354 5252-5257 NNS denotes genes
T3355 5258-5260 IN denotes by
T3356 5261-5269 VBG denotes bringing
T3357 5270-5278 RB denotes together
T3358 5279-5286 JJ denotes distant
T3359 5287-5294 NNS denotes regions
T3360 5295-5297 IN denotes of
T3361 5298-5301 NNP denotes DNA
T3362 5302-5305 CC denotes and
T3363 5306-5316 VBN denotes associated
T3364 5317-5324 NNS denotes factors
T3365 5324-5325 . denotes .
T3366 5326-5338 RB denotes Specifically
T3367 5338-5339 , denotes ,
T3368 5340-5343 NNP denotes HMG
T3369 5344-5352 NNS denotes proteins
T3370 5353-5357 VBP denotes have
T3371 5358-5362 VBN denotes been
T3372 5363-5368 VBN denotes shown
T3373 5369-5371 TO denotes to
T3374 5372-5380 VB denotes modulate
T3375 5381-5389 JJ denotes β-globin
T3376 5390-5395 NNS denotes genes
T3377 5396-5397 NNP denotes [
T3378 5397-5399 CD denotes 18
T3379 5400-5402 CD denotes 21
T3380 5402-5403 NN denotes ]
T3381 5403-5404 . denotes .
T3382 5405-5408 DT denotes The
T3383 5409-5414 NN denotes mouse
T3384 5415-5423 NN denotes β-globin
T3385 5424-5429 NNS denotes genes
T3386 5431-5433 NN denotes ɛy
T3387 5433-5434 , denotes ,
T3388 5435-5438 CD denotes βh1
T3389 5438-5439 , denotes ,
T3390 5440-5447 NN denotes β-major
T3391 5447-5448 , denotes ,
T3392 5449-5452 CC denotes and
T3393 5453-5460 JJ denotes β-minor
T3394 5462-5465 VBP denotes are
T3395 5466-5475 VBN denotes clustered
T3396 5476-5478 IN denotes on
T3397 5479-5489 NN denotes Chromosome
T3398 5490-5491 CD denotes 7
T3399 5492-5495 CC denotes and
T3400 5496-5500 PRP denotes they
T3401 5501-5504 VBP denotes are
T3402 5505-5511 RB denotes highly
T3403 5512-5522 RB denotes homologous
T3404 5523-5525 TO denotes to
T3405 5526-5531 PRP$ denotes their
T3406 5532-5537 JJ denotes human
T3407 5538-5550 NNS denotes counterparts
T3408 5551-5553 IN denotes in
T3409 5554-5568 JJ denotes organizational
T3410 5569-5578 NN denotes structure
T3411 5579-5582 CC denotes and
T3412 5583-5591 NN denotes function
T3413 5592-5593 NNP denotes [
T3414 5593-5595 CD denotes 22
T3415 5595-5596 NNP denotes ]
T3416 5596-5597 . denotes .
T3417 5598-5608 JJ denotes High-level
T3418 5609-5619 NN denotes expression
T3419 5620-5622 IN denotes of
T3420 5623-5628 DT denotes these
T3421 5629-5634 NNS denotes genes
T3422 5635-5643 VBZ denotes requires
T3423 5644-5645 DT denotes a
T3424 5646-5656 JJ denotes regulatory
T3425 5657-5664 NN denotes element
T3426 5664-5665 , denotes ,
T3427 5666-5669 DT denotes the
T3428 5670-5675 NN denotes locus
T3429 5676-5683 NN denotes control
T3430 5684-5690 NN denotes region
T3431 5691-5695 WDT denotes that
T3432 5696-5698 VBZ denotes is
T3433 5699-5712 VBN denotes characterized
T3434 5713-5715 IN denotes by
T3435 5716-5717 DT denotes a
T3436 5718-5721 NN denotes set
T3437 5722-5724 IN denotes of
T3438 5725-5733 NN denotes nuclease
T3439 5734-5748 JJ denotes hypersensitive
T3440 5749-5754 NNS denotes sites
T3441 5755-5761 VBN denotes spread
T3442 5762-5766 IN denotes over
T3443 5767-5769 CD denotes 25
T3444 5770-5772 NN denotes kb
T3445 5773-5780 VBN denotes located
T3446 5781-5782 CD denotes 5
T3447 5782-5783 NN denotes ′
T3448 5784-5786 IN denotes of
T3449 5787-5790 DT denotes the
T3450 5791-5793 JJ denotes ɛy
T3451 5794-5798 NN denotes gene
T3452 5799-5800 NNP denotes [
T3453 5800-5802 CD denotes 23
T3454 5802-5803 NNP denotes ]
T3455 5803-5804 . denotes .
T3456 5805-5808 DT denotes The
T3457 5809-5817 JJ denotes β-globin
T3458 5818-5823 NNS denotes genes
T3459 5824-5827 VBP denotes are
T3460 5828-5837 VBN denotes expressed
T3461 5838-5840 IN denotes in
T3462 5841-5842 DT denotes a
T3463 5843-5849 NN denotes tissue
T3464 5849-5850 : denotes -
T3465 5851-5854 CC denotes and
T3466 5855-5875 JJ denotes development-specific
T3467 5876-5883 NN denotes fashion
T3468 5883-5884 . denotes .
T3469 5885-5887 IN denotes In
T3470 5888-5892 NNS denotes mice
T3471 5892-5893 , denotes ,
T3472 5894-5908 VBZ denotes erythropoiesis
T3473 5909-5919 VBZ denotes originates
T3474 5920-5922 IN denotes in
T3475 5923-5926 DT denotes the
T3476 5927-5936 JJ denotes embryonic
T3477 5937-5941 NN denotes yolk
T3478 5942-5945 NN denotes sac
T3479 5946-5951 WRB denotes where
T3480 5952-5961 JJ denotes primitive
T3481 5962-5971 JJ denotes erythroid
T3482 5972-5977 NNS denotes cells
T3483 5978-5985 VBP denotes express
T3484 5986-5988 NN denotes ɛy
T3485 5989-5992 CC denotes and
T3486 5993-5997 JJ denotes βh-1
T3487 5998-6005 NNS denotes globins
T3488 6006-6007 NNP denotes [
T3489 6007-6009 CD denotes 22
T3490 6009-6010 NNP denotes ]
T3491 6010-6011 . denotes .
T3492 6012-6014 IN denotes At
T3493 6015-6019 CD denotes 11.5
T3494 6020-6021 LS denotes d
T3495 6022-6026 NN denotes post
T3496 6027-6033 NN denotes coitus
T3497 6034-6035 -LRB- denotes (
T3498 6035-6038 FW denotes dpc
T3499 6038-6039 -RRB- denotes )
T3500 6039-6040 , denotes ,
T3501 6041-6055 VBZ denotes erythropoiesis
T3502 6056-6062 NNS denotes shifts
T3503 6063-6065 TO denotes to
T3504 6066-6069 DT denotes the
T3505 6070-6075 JJ denotes fetal
T3506 6076-6081 NN denotes liver
T3507 6082-6087 WRB denotes where
T3508 6088-6098 JJ denotes definitive
T3509 6099-6108 JJ denotes erythroid
T3510 6109-6114 NNS denotes cells
T3511 6115-6122 VBP denotes express
T3512 6123-6128 NN denotes adult
T3513 6129-6130 NN denotes β
T3514 6131-6138 NNS denotes globins
T3515 6139-6140 -LRB- denotes (
T3516 6140-6141 FW denotes β
T3517 6142-6147 JJ denotes major
T3518 6148-6151 CC denotes and
T3519 6152-6157 JJ denotes minor
T3520 6157-6158 -RRB- denotes )
T3521 6159-6160 NNP denotes [
T3522 6160-6162 CD denotes 22
T3523 6162-6163 NNP denotes ]
T3524 6163-6164 . denotes .
T3525 6165-6168 DT denotes The
T3526 6169-6171 JJ denotes ɛy
T3527 6172-6176 NN denotes gene
T3528 6177-6179 VBZ denotes is
T3529 6180-6188 VBN denotes silenced
T3530 6189-6191 IN denotes in
T3531 6192-6202 JJ denotes definitive
T3532 6203-6212 JJ denotes erythroid
T3533 6213-6218 NNS denotes cells
T3534 6218-6219 . denotes .
T3535 6220-6223 DT denotes The
T3536 6224-6233 NN denotes mechanism
T3537 6234-6236 IN denotes of
T3538 6237-6246 VBG denotes silencing
T3539 6247-6249 IN denotes of
T3540 6250-6253 PRP$ denotes its
T3541 6254-6259 JJ denotes human
T3542 6260-6271 NN denotes counterpart
T3543 6271-6272 , denotes ,
T3544 6273-6274 NN denotes ɛ
T3545 6275-6281 NN denotes globin
T3546 6281-6282 , denotes ,
T3547 6283-6286 VBZ denotes has
T3548 6287-6291 VBN denotes been
T3549 6292-6299 VBN denotes studied
T3550 6300-6311 RB denotes extensively
T3551 6311-6312 . denotes .
T3552 6313-6315 IN denotes In
T3553 6316-6326 JJ denotes definitive
T3554 6327-6341 NNS denotes erythropoiesis
T3555 6341-6342 , denotes ,
T3556 6343-6344 NN denotes ɛ
T3557 6345-6347 VBZ denotes is
T3558 6348-6357 VBN denotes activated
T3559 6358-6361 CC denotes and
T3560 6362-6370 VBN denotes silenced
T3561 6371-6383 RB denotes autonomously
T3562 6384-6385 NNP denotes [
T3563 6385-6390 CD denotes 24,25
T3564 6390-6391 NNP denotes ]
T3565 6391-6392 , denotes ,
T3566 6393-6401 IN denotes although
T3567 6402-6404 IN denotes in
T3568 6405-6414 JJ denotes primitive
T3569 6415-6429 NN denotes erythropoiesis
T3570 6430-6431 NN denotes ɛ
T3571 6432-6436 RB denotes also
T3572 6437-6444 VBZ denotes appears
T3573 6445-6447 TO denotes to
T3574 6448-6450 VB denotes be
T3575 6451-6460 VBN denotes regulated
T3576 6461-6474 RB denotes competitively
T3577 6475-6476 NNP denotes [
T3578 6476-6478 CD denotes 26
T3579 6478-6479 NNP denotes ]
T3580 6479-6480 . denotes .
T3581 6481-6484 DT denotes The
T3582 6485-6493 NN denotes γ-globin
T3583 6494-6496 TO denotes to
T3584 6497-6502 NN denotes adult
T3585 6503-6511 NN denotes β-globin
T3586 6512-6518 NN denotes switch
T3587 6519-6521 VBZ denotes is
T3588 6522-6532 VBN denotes controlled
T3589 6533-6535 IN denotes by
T3590 6536-6544 NN denotes promoter
T3591 6545-6556 NN denotes competition
T3592 6557-6560 IN denotes for
T3593 6561-6564 DT denotes the
T3594 6565-6568 NNP denotes LCR
T3595 6569-6570 NNP denotes [
T3596 6570-6575 CD denotes 24,25
T3597 6575-6576 NNP denotes ]
T3598 6576-6577 . denotes .
T3599 6578-6581 PDT denotes All
T3600 6582-6585 DT denotes the
T3601 6586-6594 NNS denotes elements
T3602 6595-6606 JJ denotes responsible
T3603 6607-6610 IN denotes for
T3604 6611-6620 VBG denotes silencing
T3605 6621-6624 DT denotes the
T3606 6625-6626 NN denotes ɛ
T3607 6627-6633 NN denotes globin
T3608 6634-6638 NN denotes gene
T3609 6639-6642 VBP denotes are
T3610 6643-6649 IN denotes within
T3611 6650-6653 DT denotes the
T3612 6654-6655 NN denotes ɛ
T3613 6656-6660 NN denotes gene
T3614 6661-6663 CC denotes or
T3615 6664-6666 IN denotes in
T3616 6667-6675 JJ denotes adjacent
T3617 6676-6685 NNS denotes sequences
T3618 6686-6687 NNP denotes [
T3619 6687-6689 CD denotes 27
T3620 6689-6690 NNP denotes ]
T3621 6690-6691 , denotes ,
T3622 6692-6702 VBG denotes suggesting
T3623 6703-6707 IN denotes that
T3624 6708-6717 VBG denotes silencing
T3625 6718-6720 VBZ denotes is
T3626 6721-6730 RB denotes primarily
T3627 6731-6735 NN denotes gene
T3628 6736-6746 JJ denotes autonomous
T3629 6746-6747 . denotes .
T3630 6748-6753 VBG denotes Using
T3631 6754-6762 NN denotes promoter
T3632 6763-6771 NN denotes deletion
T3633 6772-6780 NNS denotes analyses
T3634 6781-6783 IN denotes in
T3635 6784-6794 JJ denotes transgenic
T3636 6795-6800 NN denotes mouse
T3637 6801-6807 NNS denotes models
T3638 6808-6811 CC denotes and
T3639 6812-6816 NN denotes cell
T3640 6817-6829 NN denotes transfection
T3641 6830-6836 NNS denotes assays
T3642 6836-6837 , denotes ,
T3643 6838-6846 JJ denotes multiple
T3644 6847-6850 NNP denotes DNA
T3645 6851-6859 NNS denotes elements
T3646 6860-6869 JJ denotes important
T3647 6870-6872 TO denotes to
T3648 6873-6876 DT denotes the
T3649 6877-6886 VBG denotes silencing
T3650 6887-6894 NN denotes process
T3651 6895-6899 VBP denotes have
T3652 6900-6904 VBN denotes been
T3653 6905-6915 RB denotes previously
T3654 6916-6926 VBN denotes identified
T3655 6927-6929 IN denotes in
T3656 6930-6934 DT denotes both
T3657 6935-6938 DT denotes the
T3658 6939-6947 NN denotes proximal
T3659 6948-6951 CC denotes and
T3660 6952-6955 DT denotes the
T3661 6956-6962 JJ denotes distal
T3662 6963-6964 NN denotes ɛ
T3663 6965-6969 NN denotes gene
T3664 6970-6978 NN denotes promoter
T3665 6979-6980 NNP denotes [
T3666 6980-6982 CD denotes 27
T3667 6982-6983 NNP denotes ]
T3668 6983-6984 . denotes .
T3669 6985-6990 PRP$ denotes Their
T3670 6991-7004 JJ denotes corresponding
T3671 7005-7018 NN denotes transcription
T3672 7019-7026 NNS denotes factors
T3673 7026-7027 , denotes ,
T3674 7028-7032 JJ denotes such
T3675 7033-7035 IN denotes as
T3676 7036-7042 NNP denotes GATA-1
T3677 7042-7043 , denotes ,
T3678 7044-7048 NNP denotes YY-1
T3679 7048-7049 , denotes ,
T3680 7050-7057 NNP denotes COUP-TF
T3681 7057-7058 , denotes ,
T3682 7059-7062 CC denotes and
T3683 7063-7067 NNP denotes DRED
T3684 7068-7072 VBP denotes have
T3685 7073-7077 VBN denotes been
T3686 7078-7088 VBN denotes identified
T3687 7089-7092 CC denotes and
T3688 7093-7098 VBN denotes shown
T3689 7099-7101 TO denotes to
T3690 7102-7110 RB denotes directly
T3691 7111-7115 NN denotes bind
T3692 7116-7118 TO denotes to
T3693 7119-7124 DT denotes these
T3694 7125-7128 NNP denotes DNA
T3695 7129-7137 NNS denotes elements
T3696 7138-7139 -LRB- denotes (
T3697 7139-7141 IN denotes as
T3698 7142-7146 NN denotes part
T3699 7147-7149 IN denotes of
T3700 7150-7157 NN denotes protein
T3701 7158-7167 NNS denotes complexes
T3702 7167-7168 -RRB- denotes )
T3703 7169-7171 TO denotes to
T3704 7172-7180 VB denotes regulate
T3705 7181-7182 NN denotes ɛ
T3706 7183-7192 VBG denotes silencing
T3707 7193-7194 NNP denotes [
T3708 7194-7196 CD denotes 27
T3709 7196-7197 NNP denotes ]
T3710 7197-7198 . denotes .
T3711 7199-7203 RB denotes Thus
T3712 7203-7204 , denotes ,
T3713 7205-7207 PRP denotes it
T3714 7208-7215 VBZ denotes appears
T3715 7216-7220 IN denotes that
T3716 7221-7224 DT denotes the
T3717 7225-7234 NN denotes silencing
T3718 7235-7237 IN denotes of
T3719 7238-7241 DT denotes the
T3720 7242-7243 NN denotes ɛ
T3721 7244-7248 NN denotes gene
T3722 7249-7257 VBZ denotes involves
T3723 7258-7259 DT denotes a
T3724 7260-7271 JJ denotes complicated
T3725 7272-7279 NN denotes network
T3726 7280-7282 IN denotes of
T3727 7283-7291 JJ denotes multiple
T3728 7292-7295 NN denotes cis
T3729 7296-7304 NNS denotes elements
T3730 7305-7308 CC denotes and
T3731 7309-7320 VBG denotes transacting
T3732 7321-7329 NNS denotes proteins
T3733 7329-7330 . denotes .
T3734 7331-7333 IN denotes In
T3735 7334-7342 NN denotes addition
T3736 7343-7345 TO denotes to
T3737 7346-7353 VBG denotes playing
T3738 7354-7356 DT denotes an
T3739 7357-7366 JJ denotes important
T3740 7367-7371 NN denotes role
T3741 7372-7374 IN denotes in
T3742 7375-7378 DT denotes the
T3743 7379-7390 NN denotes development
T3744 7391-7393 IN denotes of
T3745 7394-7397 DT denotes the
T3746 7398-7405 JJ denotes central
T3747 7406-7413 JJ denotes nervous
T3748 7414-7420 NN denotes system
T3749 7421-7422 NN denotes [
T3750 7422-7423 CD denotes 8
T3751 7424-7426 CD denotes 11
T3752 7426-7427 NNP denotes ]
T3753 7427-7428 , denotes ,
T3754 7429-7438 NN denotes cartilage
T3755 7439-7440 NNP denotes [
T3756 7440-7447 CD denotes 6,12,13
T3757 7447-7448 NNP denotes ]
T3758 7448-7449 , denotes ,
T3759 7450-7453 CC denotes and
T3760 7454-7460 NN denotes muscle
T3761 7461-7462 NNP denotes [
T3762 7462-7467 CD denotes 14,15
T3763 7467-7468 NNP denotes ]
T3764 7468-7469 , denotes ,
T3765 7470-7472 PRP denotes it
T3766 7473-7476 VBD denotes was
T3767 7477-7482 VBN denotes shown
T3768 7483-7487 IN denotes that
T3769 7488-7492 NNP denotes Sox6
T3770 7493-7495 VBZ denotes is
T3771 7496-7507 VBN denotes upregulated
T3772 7508-7510 IN denotes in
T3773 7511-7520 JJ denotes long-term
T3774 7521-7534 NN denotes hematopoiesis
T3775 7535-7539 NN denotes stem
T3776 7540-7545 NNS denotes cells
T3777 7546-7547 -LRB- denotes (
T3778 7547-7553 NNP denotes LT-HSC
T3779 7553-7554 -RRB- denotes )
T3780 7555-7563 VBN denotes compared
T3781 7564-7568 IN denotes with
T3782 7569-7580 JJ denotes multipotent
T3783 7581-7592 NNS denotes progenitors
T3784 7593-7595 IN denotes of
T3785 7596-7601 NN denotes adult
T3786 7602-7607 NN denotes mouse
T3787 7608-7612 NN denotes bone
T3788 7613-7619 NN denotes marrow
T3789 7620-7627 NN denotes lineage
T3790 7628-7629 NNP denotes [
T3791 7629-7631 CD denotes 28
T3792 7631-7632 NNP denotes ]
T3793 7632-7633 . denotes .
T3794 7634-7636 IN denotes In
T3795 7637-7641 DT denotes this
T3796 7642-7647 NN denotes study
T3797 7647-7648 , denotes ,
T3798 7649-7651 PRP denotes we
T3799 7652-7660 VBP denotes describe
T3800 7661-7665 IN denotes that
T3801 7666-7670 NNP denotes Sox6
T3802 7671-7675 RB denotes also
T3803 7676-7682 VBZ denotes exerts
T3804 7683-7694 JJ denotes pleiotropic
T3805 7695-7702 NNS denotes effects
T3806 7703-7705 IN denotes on
T3807 7706-7720 NN denotes erythropoiesis
T3808 7720-7721 . denotes .
T3809 7722-7727 DT denotes These
T3810 7728-7735 NNS denotes effects
T3811 7736-7743 VBP denotes include
T3812 7744-7751 VBN denotes delayed
T3813 7752-7762 NN denotes maturation
T3814 7763-7765 IN denotes of
T3815 7766-7778 NNS denotes erythrocytes
T3816 7779-7780 -LRB- denotes (
T3817 7780-7784 IN denotes that
T3818 7785-7793 RB denotes normally
T3819 7794-7803 JJ denotes enucleate
T3820 7804-7809 RB denotes prior
T3821 7810-7812 TO denotes to
T3822 7813-7821 VBG denotes entering
T3823 7822-7825 DT denotes the
T3824 7826-7837 NN denotes bloodstream
T3825 7838-7839 NNP denotes [
T3826 7839-7841 CD denotes 27
T3827 7841-7842 NNP denotes ]
T3828 7842-7843 -RRB- denotes )
T3829 7844-7847 CC denotes and
T3830 7848-7854 JJR denotes higher
T3831 7855-7865 NN denotes expression
T3832 7866-7868 IN denotes of
T3833 7869-7878 JJ denotes embryonic
T3834 7879-7885 NN denotes globin
T3835 7886-7891 NNS denotes genes
T3836 7891-7892 . denotes .
T3837 7893-7896 DT denotes The
T3838 7897-7901 RBS denotes most
T3839 7902-7909 JJ denotes extreme
T3840 7910-7916 NN denotes effect
T3841 7917-7919 VBZ denotes is
T3842 7920-7923 DT denotes the
T3843 7924-7935 NN denotes persistence
T3844 7936-7938 IN denotes of
T3845 7939-7943 JJ denotes high
T3846 7944-7954 NN denotes expression
T3847 7955-7957 IN denotes of
T3848 7958-7961 DT denotes the
T3849 7962-7971 JJ denotes embryonic
T3850 7972-7974 NN denotes ɛy
T3851 7975-7981 NN denotes globin
T3852 7982-7986 NN denotes gene
T3853 7986-7987 . denotes .
T3854 7988-7992 RB denotes Here
T3855 7993-7995 PRP denotes we
T3856 7996-8004 VBP denotes describe
T3857 8005-8008 CC denotes and
T3858 8009-8021 VBP denotes characterize
T3859 8022-8025 DT denotes the
T3860 8026-8033 NNS denotes effects
T3861 8034-8036 IN denotes of
T3862 8037-8041 NNP denotes Sox6
T3863 8042-8044 IN denotes on
T3864 8045-8048 DT denotes the
T3865 8049-8051 JJ denotes ɛy
T3866 8052-8058 NN denotes globin
T3867 8059-8063 NN denotes gene
T3868 8063-8064 . denotes .
T3869 8065-8067 PRP denotes We
T3870 8068-8072 VBP denotes show
T3871 8073-8077 IN denotes that
T3872 8078-8082 JJ denotes Sox6
T3873 8083-8088 NNS denotes binds
T3874 8089-8091 TO denotes to
T3875 8092-8095 DT denotes the
T3876 8096-8104 JJ denotes proximal
T3877 8105-8113 NN denotes promoter
T3878 8114-8116 IN denotes of
T3879 8117-8119 JJ denotes ɛy
T3880 8120-8126 NN denotes globin
T3881 8127-8130 CC denotes and
T3882 8131-8140 VBZ denotes represses
T3883 8141-8144 PRP$ denotes its
T3884 8145-8158 NN denotes transcription
T3885 8158-8159 . denotes .
T3886 8160-8162 IN denotes In
T3887 8163-8172 JJ denotes wild-type
T3888 8173-8174 -LRB- denotes (
T3889 8174-8176 NNP denotes WT
T3890 8176-8177 -RRB- denotes )
T3891 8178-8182 NNS denotes mice
T3892 8182-8183 , denotes ,
T3893 8184-8188 NNP denotes Sox6
T3894 8189-8191 VBZ denotes is
T3895 8192-8195 RB denotes not
T3896 8196-8205 VBN denotes expressed
T3897 8206-8208 IN denotes in
T3898 8209-8213 NN denotes yolk
T3899 8214-8217 NN denotes sac
T3900 8218-8223 NN denotes blood
T3901 8224-8231 NNS denotes islands
T3902 8231-8232 , denotes ,
T3903 8233-8236 CC denotes but
T3904 8237-8239 VBZ denotes is
T3905 8240-8249 VBN denotes expressed
T3906 8250-8252 IN denotes in
T3907 8253-8258 JJ denotes fetal
T3908 8259-8264 NN denotes liver
T3909 8264-8265 , denotes ,
T3910 8266-8269 DT denotes the
T3911 8270-8278 JJ denotes opposite
T3912 8279-8289 NN denotes expression
T3913 8290-8297 NN denotes pattern
T3914 8298-8300 IN denotes of
T3915 8301-8303 JJ denotes ɛy
T3916 8304-8310 NN denotes globin
T3917 8310-8311 . denotes .
T3918 8312-8314 IN denotes In
T3919 8315-8318 DT denotes the
T3920 8319-8326 NN denotes absence
T3921 8327-8329 IN denotes of
T3922 8330-8334 NNP denotes Sox6
T3923 8334-8335 , denotes ,
T3924 8336-8338 JJ denotes ɛy
T3925 8339-8345 NN denotes globin
T3926 8346-8348 VBZ denotes is
T3927 8349-8360 RB denotes ectopically
T3928 8361-8370 VBN denotes expressed
T3929 8371-8373 IN denotes in
T3930 8374-8377 DT denotes the
T3931 8378-8383 JJ denotes fetal
T3932 8384-8389 NN denotes liver
T3933 8389-8390 , denotes ,
T3934 8391-8404 VBG denotes demonstrating
T3935 8405-8409 IN denotes that
T3936 8410-8414 JJ denotes Sox6
T3937 8415-8424 NNS denotes functions
T3938 8425-8427 IN denotes in
T3939 8428-8438 JJ denotes definitive
T3940 8439-8453 NNS denotes erythropoiesis
T3941 8453-8454 . denotes .
T4964 8465-8475 JJ denotes Persistent
T4965 8476-8486 NN denotes Expression
T4966 8487-8489 IN denotes of
T4967 8490-8493 DT denotes the
T4968 8494-8503 NNP denotes Embryonic
T4969 8504-8510 NNP denotes Globin
T4970 8510-8511 , denotes ,
T4971 8512-8514 NN denotes ɛy
T4972 8514-8515 , denotes ,
T4973 8516-8518 IN denotes in
T4974 8519-8533 JJ denotes Sox6-Deficient
T4975 8534-8538 NNP denotes Mice
T4976 8539-8542 DT denotes The
T4977 8543-8545 JJ denotes ɛy
T4978 8546-8552 NN denotes globin
T4979 8553-8557 NN denotes gene
T4980 8558-8561 VBD denotes was
T4981 8562-8571 RB denotes initially
T4982 8572-8582 VBN denotes identified
T4983 8583-8585 IN denotes as
T4984 8586-8588 DT denotes an
T4985 8589-8600 JJ denotes upregulated
T4986 8601-8611 NN denotes transcript
T4987 8612-8614 IN denotes in
T4988 8615-8618 DT denotes the
T4989 8619-8625 JJ denotes p 100H
T4990 8626-8631 NN denotes mouse
T4991 8632-8637 VBG denotes using
T4992 8638-8649 JJ denotes subtractive
T4993 8650-8663 NN denotes hybridization
T4994 8664-8666 TO denotes to
T4995 8667-8675 VB denotes identify
T4996 8676-8680 JJ denotes Sox6
T4997 8681-8691 JJ denotes downstream
T4998 8692-8699 NNS denotes targets
T4999 8699-8700 . denotes .
T5000 8701-8705 DT denotes This
T5001 8706-8713 JJ denotes initial
T5002 8714-8725 NN denotes observation
T5003 8726-8729 VBD denotes was
T5004 8730-8739 VBN denotes confirmed
T5005 8740-8742 IN denotes in
T5006 8743-8745 DT denotes an
T5007 8746-8757 JJ denotes independent
T5008 8758-8767 JJ denotes knock-out
T5009 8768-8774 NN denotes allele
T5010 8775-8777 IN denotes of
T5011 8778-8782 NNP denotes Sox6
T5012 8783-8784 NNP denotes [
T5013 8784-8786 CD denotes 13
T5014 8786-8787 NNP denotes ]
T5015 8788-8793 VBG denotes using
T5016 8794-8803 JJ denotes real-time
T5017 8804-8814 NN denotes polymerase
T5018 8815-8820 NN denotes chain
T5019 8821-8829 NN denotes reaction
T5020 8830-8831 -LRB- denotes (
T5021 8831-8834 NNP denotes PCR
T5022 8834-8835 -RRB- denotes )
T5023 8836-8837 -LRB- denotes (
T5024 8837-8848 JJ denotes unpublished
T5025 8849-8853 NNS denotes data
T5026 8853-8854 -RRB- denotes )
T5027 8854-8855 . denotes .
T5028 8856-8865 JJ denotes Real-time
T5029 8866-8869 NNP denotes PCR
T5030 8870-8873 VBD denotes was
T5031 8874-8878 VBN denotes used
T5032 8879-8881 TO denotes to
T5033 8882-8892 VB denotes quantitate
T5034 8893-8896 DT denotes the
T5035 8897-8907 NN denotes expression
T5036 8908-8914 NNS denotes levels
T5037 8915-8917 IN denotes of
T5038 8918-8923 JJ denotes other
T5039 8924-8930 NN denotes globin
T5040 8931-8936 NNS denotes genes
T5041 8937-8939 IN denotes in
T5042 8940-8945 JJ denotes p100H
T5043 8946-8952 JJ denotes mutant
T5044 8953-8956 CC denotes and
T5045 8957-8959 NNP denotes WT
T5046 8960-8965 NN denotes mouse
T5047 8966-8972 NNS denotes livers
T5048 8973-8975 IN denotes at
T5049 8976-8979 CD denotes two
T5050 8980-8993 JJ denotes developmental
T5051 8994-9000 NNS denotes stages
T5052 9000-9001 , denotes ,
T5053 9002-9006 CD denotes 15.5
T5054 9007-9010 NN denotes dpc
T5055 9011-9014 CC denotes and
T5056 9015-9019 CD denotes 18.5
T5057 9020-9023 NN denotes dpc
T5058 9023-9024 . denotes .
T5059 9025-9027 IN denotes As
T5060 9028-9033 VBN denotes shown
T5061 9034-9036 IN denotes in
T5062 9037-9043 NN denotes Figure
T5063 9044-9045 CD denotes 1
T5064 9045-9046 , denotes ,
T5065 9047-9050 DT denotes the
T5066 9051-9053 JJ denotes ɛy
T5067 9054-9058 NN denotes gene
T5068 9059-9061 VBZ denotes is
T5069 9062-9071 VBN denotes expressed
T5070 9072-9074 IN denotes at
T5071 9075-9079 JJ denotes high
T5072 9080-9086 NNS denotes levels
T5073 9087-9089 IN denotes at
T5074 9090-9094 DT denotes both
T5075 9095-9099 NN denotes time
T5076 9100-9106 NNS denotes points
T5077 9107-9109 IN denotes in
T5078 9110-9116 JJ denotes mutant
T5079 9117-9121 NNS denotes mice
T5080 9121-9122 , denotes ,
T5081 9123-9125 IN denotes in
T5082 9126-9134 NN denotes contrast
T5083 9135-9137 TO denotes to
T5084 9138-9141 DT denotes the
T5085 9142-9149 NN denotes decline
T5086 9150-9152 IN denotes in
T5087 9153-9163 NN denotes expression
T5088 9164-9172 VBN denotes observed
T5089 9173-9175 IN denotes in
T5090 9176-9178 NNP denotes WT
T5091 9179-9183 NNS denotes mice
T5092 9183-9184 . denotes .
T5093 9185-9187 DT denotes No
T5094 9188-9198 NN denotes difference
T5095 9199-9202 VBD denotes was
T5096 9203-9207 VBN denotes seen
T5097 9208-9215 IN denotes between
T5098 9216-9218 NNP denotes WT
T5099 9219-9222 CC denotes and
T5100 9223-9235 JJ denotes heterozygous
T5101 9236-9240 NNS denotes mice
T5102 9241-9242 -LRB- denotes (
T5103 9242-9253 JJ denotes unpublished
T5104 9254-9258 NNS denotes data
T5105 9258-9259 -RRB- denotes )
T5106 9259-9260 . denotes .
T5107 9261-9274 RB denotes Interestingly
T5108 9274-9275 , denotes ,
T5109 9276-9279 DT denotes the
T5110 9280-9290 NN denotes expression
T5111 9291-9297 NNS denotes levels
T5112 9298-9300 IN denotes of
T5113 9301-9304 DT denotes the
T5114 9305-9310 JJ denotes other
T5115 9311-9314 CD denotes two
T5116 9315-9324 JJ denotes embryonic
T5117 9325-9331 NN denotes globin
T5118 9332-9337 NNS denotes genes
T5119 9338-9339 -LRB- denotes (
T5120 9339-9340 NN denotes ζ
T5121 9341-9344 CC denotes and
T5122 9345-9348 CD denotes βh1
T5123 9348-9349 -RRB- denotes )
T5124 9350-9353 VBP denotes are
T5125 9354-9358 RB denotes also
T5126 9359-9365 JJR denotes higher
T5127 9366-9368 IN denotes in
T5128 9369-9374 JJ denotes p100H
T5129 9375-9385 JJ denotes homozygous
T5130 9386-9390 NNS denotes mice
T5131 9390-9391 , denotes ,
T5132 9392-9400 VBN denotes compared
T5133 9401-9405 IN denotes with
T5134 9406-9408 NNP denotes WT
T5135 9409-9413 NNS denotes mice
T5136 9413-9414 , denotes ,
T5137 9415-9418 CC denotes but
T5138 9419-9421 TO denotes to
T5139 9422-9423 DT denotes a
T5140 9424-9428 JJ denotes much
T5141 9429-9435 JJR denotes lesser
T5142 9436-9442 NN denotes extent
T5143 9443-9447 IN denotes than
T5144 9448-9452 VBN denotes seen
T5145 9453-9456 IN denotes for
T5146 9457-9459 JJ denotes ɛy
T5147 9460-9466 NN denotes globin
T5148 9467-9469 IN denotes at
T5149 9470-9474 CD denotes 18.5
T5150 9475-9478 NN denotes dpc
T5151 9479-9480 -LRB- denotes (
T5152 9480-9486 NN denotes Figure
T5153 9487-9488 CD denotes 1
T5154 9488-9489 -RRB- denotes )
T5155 9489-9490 . denotes .
T5156 9491-9499 RB denotes Moreover
T5157 9499-9500 , denotes ,
T5158 9501-9504 DT denotes the
T5159 9505-9515 NN denotes expression
T5160 9516-9521 NN denotes level
T5161 9522-9524 IN denotes of
T5162 9525-9530 NN denotes adult
T5163 9531-9532 NN denotes β
T5164 9533-9539 NN denotes globin
T5165 9540-9542 VBZ denotes is
T5166 9543-9547 RB denotes also
T5167 9548-9556 RB denotes somewhat
T5168 9557-9563 JJR denotes higher
T5169 9564-9566 IN denotes in
T5170 9567-9572 JJ denotes p100H
T5171 9573-9583 JJ denotes homozygous
T5172 9584-9588 NNS denotes mice
T5173 9589-9593 IN denotes than
T5174 9594-9596 IN denotes in
T5175 9597-9599 NNP denotes WT
T5176 9600-9604 NNS denotes mice
T5177 9605-9607 IN denotes at
T5178 9608-9612 CD denotes 18.5
T5179 9613-9616 NN denotes dpc
T5180 9617-9618 -LRB- denotes (
T5181 9618-9624 NN denotes Figure
T5182 9625-9626 CD denotes 1
T5183 9626-9627 -RRB- denotes )
T5184 9627-9628 . denotes .
T5185 9629-9638 JJ denotes Perinatal
T5186 9639-9648 NN denotes lethality
T5187 9649-9651 IN denotes of
T5188 9652-9658 JJ denotes mutant
T5189 9659-9663 NNS denotes mice
T5190 9664-9665 -LRB- denotes (
T5191 9665-9675 RB denotes presumably
T5192 9676-9680 IN denotes from
T5193 9681-9684 DT denotes the
T5194 9685-9690 NN denotes heart
T5195 9691-9697 NN denotes defect
T5196 9698-9699 NNP denotes [
T5197 9699-9701 CD denotes 14
T5198 9701-9702 NNP denotes ]
T5199 9702-9703 -RRB- denotes )
T5200 9704-9713 VBZ denotes precludes
T5201 9714-9716 PRP denotes us
T5202 9717-9721 IN denotes from
T5203 9722-9732 VBG denotes evaluating
T5204 9733-9742 JJ denotes postnatal
T5205 9743-9749 NN denotes globin
T5206 9750-9760 NN denotes expression
T5207 9760-9761 . denotes .
T5208 9762-9765 DT denotes The
T5209 9766-9772 NNS denotes graphs
T5210 9773-9775 IN denotes in
T5211 9776-9782 NN denotes Figure
T5212 9783-9784 CD denotes 1
T5213 9785-9795 VBP denotes illustrate
T5214 9796-9800 JJ denotes real
T5215 9801-9805 NN denotes time
T5216 9806-9809 NNP denotes PCR
T5217 9810-9817 NNS denotes results
T5218 9818-9822 WDT denotes that
T5219 9823-9827 VBD denotes were
T5220 9828-9837 VBN denotes performed
T5221 9838-9840 IN denotes in
T5222 9841-9851 NN denotes triplicate
T5223 9852-9853 -LRB- denotes (
T5224 9853-9861 JJ denotes standard
T5225 9862-9871 NN denotes deviation
T5226 9872-9874 IN denotes of
T5227 9875-9878 DT denotes the
T5228 9879-9883 NN denotes data
T5229 9884-9886 VBZ denotes is
T5230 9887-9892 VBN denotes shown
T5231 9893-9895 IN denotes by
T5232 9896-9901 NN denotes error
T5233 9902-9906 NNS denotes bars
T5234 9906-9907 -RRB- denotes )
T5235 9907-9908 . denotes .
T5236 9909-9916 IN denotes Because
T5237 9917-9920 DT denotes all
T5238 9921-9923 IN denotes of
T5239 9924-9927 DT denotes the
T5240 9928-9934 NNS denotes assays
T5241 9935-9939 VBD denotes were
T5242 9940-9949 VBN denotes performed
T5243 9950-9952 IN denotes at
T5244 9953-9956 DT denotes the
T5245 9957-9961 JJ denotes same
T5246 9962-9966 NN denotes time
T5247 9967-9971 IN denotes with
T5248 9972-9975 DT denotes the
T5249 9976-9980 JJ denotes same
T5250 9981-9989 JJ denotes internal
T5251 9990-9997 NN denotes control
T5252 9997-9998 , denotes ,
T5253 9999-10002 DT denotes the
T5254 10003-10009 NNS denotes levels
T5255 10010-10015 VBN denotes shown
T5256 10016-10019 VBP denotes are
T5257 10020-10028 JJ denotes relative
T5258 10029-10035 NNS denotes levels
T5259 10036-10039 CC denotes and
T5260 10040-10043 VBP denotes are
T5261 10044-10048 RB denotes thus
T5262 10049-10059 JJ denotes comparable
T5263 10060-10066 IN denotes across
T5264 10067-10070 DT denotes all
T5265 10071-10078 NNS denotes samples
T5266 10079-10082 CC denotes and
T5267 10083-10086 VBP denotes are
T5268 10087-10089 IN denotes in
T5269 10090-10099 NN denotes agreement
T5270 10100-10104 IN denotes with
T5271 10105-10115 RB denotes previously
T5272 10116-10125 VBN denotes published
T5273 10126-10133 NNS denotes results
T5274 10134-10137 IN denotes for
T5275 10138-10140 NNP denotes WT
T5276 10141-10146 JJ denotes fetal
T5277 10147-10151 NNS denotes mice
T5278 10152-10153 NNP denotes [
T5279 10153-10155 CD denotes 29
T5280 10155-10156 NNP denotes ]
T5281 10156-10157 . denotes .
T5282 10158-10160 PRP denotes We
T5283 10161-10165 VBP denotes note
T5284 10166-10170 IN denotes that
T5285 10171-10174 DT denotes the
T5286 10175-10180 NN denotes level
T5287 10181-10183 IN denotes of
T5288 10184-10186 JJ denotes ɛy
T5289 10187-10197 NN denotes expression
T5290 10198-10200 IN denotes in
T5291 10201-10204 DT denotes the
T5292 10205-10211 NNS denotes livers
T5293 10212-10214 IN denotes of
T5294 10215-10219 CD denotes 15.5
T5295 10220-10223 NN denotes dpc
T5296 10224-10227 CC denotes and
T5297 10228-10232 CD denotes 18.5
T5298 10233-10236 NN denotes dpc
T5299 10237-10247 JJ denotes homozygous
T5300 10248-10254 JJ denotes mutant
T5301 10255-10259 NNS denotes mice
T5302 10260-10262 VBZ denotes is
T5303 10263-10276 RB denotes statistically
T5304 10277-10287 JJ denotes equivalent
T5305 10288-10290 TO denotes to
T5306 10291-10294 DT denotes the
T5307 10295-10300 NN denotes level
T5308 10301-10303 IN denotes of
T5309 10304-10308 NN denotes βmaj
T5310 10308-10309 NN denotes /
T5311 10309-10312 NN denotes min
T5312 10313-10323 NN denotes expression
T5313 10324-10326 IN denotes in
T5314 10327-10330 DT denotes the
T5315 10331-10337 NNS denotes livers
T5316 10338-10340 IN denotes of
T5317 10341-10345 CD denotes 15.5
T5318 10346-10349 NN denotes dpc
T5319 10350-10353 CC denotes and
T5320 10354-10358 CD denotes 18.5
T5321 10359-10362 NN denotes dpc
T5322 10363-10373 JJ denotes homozygous
T5323 10374-10376 NNP denotes WT
T5324 10377-10381 NNS denotes mice
T5325 10381-10382 . denotes .
T6363 10796-10808 NNP denotes Transfection
T6364 10809-10816 NNP denotes Studies
T6365 10817-10822 VBG denotes Using
T6366 10823-10828 NNP denotes GM979
T6367 10829-10834 NNP denotes Cells
T6368 10835-10843 NNP denotes Indicate
T6369 10844-10848 WDT denotes That
T6370 10849-10853 NNP denotes Sox6
T6371 10854-10862 RB denotes Directly
T6372 10863-10872 NNPS denotes Represses
T6373 10873-10876 DT denotes the
T6374 10877-10879 NN denotes ɛy
T6375 10880-10884 NNP denotes Gene
T6376 10885-10893 NNP denotes Promoter
T6377 10894-10896 IN denotes at
T6378 10897-10900 DT denotes the
T6379 10901-10916 NNP denotes Transcriptional
T6380 10917-10922 NNP denotes Level
T6381 10923-10932 JJ denotes Real-time
T6382 10933-10936 NNP denotes PCR
T6383 10937-10943 NNS denotes assays
T6384 10944-10945 -LRB- denotes (
T6385 10945-10951 NN denotes Figure
T6386 10952-10953 CD denotes 1
T6387 10953-10954 -RRB- denotes )
T6388 10955-10962 NN denotes measure
T6389 10963-10975 JJ denotes steady-state
T6390 10976-10982 NNS denotes levels
T6391 10983-10985 IN denotes of
T6392 10986-10988 JJ denotes ɛy
T6393 10989-10993 NNP denotes mRNA
T6394 10993-10994 , denotes ,
T6395 10995-10998 RB denotes not
T6396 10999-11014 JJ denotes transcriptional
T6397 11015-11023 NN denotes activity
T6398 11024-11026 IN denotes of
T6399 11027-11030 DT denotes the
T6400 11031-11033 JJ denotes ɛy
T6401 11034-11042 NN denotes promoter
T6402 11042-11043 . denotes .
T6403 11044-11046 TO denotes To
T6404 11047-11058 VB denotes investigate
T6405 11059-11066 IN denotes whether
T6406 11067-11071 JJ denotes Sox6
T6407 11072-11080 RB denotes directly
T6408 11081-11085 VBZ denotes acts
T6409 11086-11088 IN denotes on
T6410 11089-11092 DT denotes the
T6411 11093-11095 JJ denotes ɛy
T6412 11096-11100 NN denotes gene
T6413 11101-11109 NN denotes promoter
T6414 11110-11112 IN denotes at
T6415 11113-11116 DT denotes the
T6416 11117-11132 JJ denotes transcriptional
T6417 11133-11138 NN denotes level
T6418 11138-11139 , denotes ,
T6419 11140-11142 PRP denotes we
T6420 11143-11147 VBD denotes used
T6421 11148-11150 DT denotes an
T6422 11151-11153 IN denotes in
T6423 11154-11159 NN denotes vitro
T6424 11160-11169 NN denotes transient
T6425 11170-11182 NN denotes transfection
T6426 11183-11188 NN denotes assay
T6427 11189-11192 CC denotes and
T6428 11193-11198 NNP denotes GM979
T6429 11199-11204 NNS denotes cells
T6430 11204-11205 , denotes ,
T6431 11206-11207 DT denotes a
T6432 11208-11214 JJ denotes murine
T6433 11215-11230 JJ denotes erythroleukemic
T6434 11231-11235 NN denotes cell
T6435 11236-11240 NN denotes line
T6436 11241-11245 WDT denotes that
T6437 11246-11255 VBZ denotes expresses
T6438 11256-11260 DT denotes both
T6439 11261-11263 NN denotes ɛy
T6440 11264-11267 CC denotes and
T6441 11268-11273 NN denotes adult
T6442 11274-11278 JJ denotes beta
T6443 11279-11286 NNS denotes globins
T6444 11287-11288 NNP denotes [
T6445 11288-11290 CD denotes 30
T6446 11290-11291 NNP denotes ]
T6447 11291-11292 . denotes .
T6448 11293-11295 PRP denotes We
T6449 11296-11305 VBD denotes generated
T6450 11306-11308 DT denotes an
T6451 11309-11311 JJ denotes ɛy
T6452 11312-11320 NN denotes promoter
T6453 11321-11329 NN denotes reporter
T6454 11330-11339 VBP denotes construct
T6455 11340-11341 -LRB- denotes (
T6456 11341-11346 JJ denotes E-Luc
T6457 11346-11347 -RRB- denotes )
T6458 11348-11350 IN denotes by
T6459 11351-11357 NN denotes fusing
T6460 11358-11359 DT denotes a
T6461 11360-11369 NN denotes micro-LCR
T6462 11370-11371 -LRB- denotes (
T6463 11371-11375 NNP denotes μLCR
T6464 11375-11376 -RRB- denotes )
T6465 11377-11384 NN denotes element
T6466 11385-11386 -LRB- denotes (
T6467 11386-11389 CD denotes 2.5
T6468 11390-11392 NN denotes kb
T6469 11392-11393 -RRB- denotes )
T6470 11394-11395 NNP denotes [
T6471 11395-11397 CD denotes 31
T6472 11397-11398 NNP denotes ]
T6473 11399-11401 TO denotes to
T6474 11402-11405 DT denotes the
T6475 11406-11408 JJ denotes ɛy
T6476 11409-11417 JJ denotes proximal
T6477 11418-11426 NN denotes promoter
T6478 11427-11428 -LRB- denotes (
T6479 11428-11431 CD denotes 2.2
T6480 11432-11434 NN denotes kb
T6481 11434-11435 -RRB- denotes )
T6482 11435-11436 , denotes ,
T6483 11437-11445 VBN denotes followed
T6484 11446-11448 IN denotes by
T6485 11449-11452 DT denotes the
T6486 11453-11463 NN denotes luciferase
T6487 11464-11472 NN denotes reporter
T6488 11473-11477 NN denotes gene
T6489 11477-11478 , denotes ,
T6490 11479-11481 IN denotes as
T6491 11482-11487 VBN denotes shown
T6492 11488-11490 IN denotes in
T6493 11491-11497 NN denotes Figure
T6494 11498-11500 CD denotes 2A
T6495 11501-11502 -LRB- denotes (
T6496 11502-11510 VBN denotes detailed
T6497 11511-11513 IN denotes in
T6498 11514-11523 NNPS denotes Materials
T6499 11524-11527 CC denotes and
T6500 11528-11535 NNPS denotes Methods
T6501 11535-11536 -RRB- denotes )
T6502 11536-11537 . denotes .
T6503 11538-11552 NNP denotes Overexpression
T6504 11553-11555 IN denotes of
T6505 11556-11560 NNP denotes Sox6
T6506 11561-11563 IN denotes in
T6507 11564-11569 NNP denotes GM979
T6508 11570-11575 NNS denotes cells
T6509 11576-11578 IN denotes by
T6510 11579-11588 JJ denotes transient
T6511 11589-11601 NN denotes transfection
T6512 11602-11607 VBZ denotes leads
T6513 11608-11610 TO denotes to
T6514 11611-11612 DT denotes a
T6515 11613-11629 JJ denotes dosage-dependent
T6516 11630-11640 NN denotes repression
T6517 11641-11643 IN denotes of
T6518 11644-11649 JJ denotes E-Luc
T6519 11650-11658 NN denotes reporter
T6520 11659-11667 NN denotes activity
T6521 11668-11669 -LRB- denotes (
T6522 11669-11675 NN denotes Figure
T6523 11676-11678 NN denotes 2B
T6524 11678-11679 -RRB- denotes )
T6525 11679-11680 . denotes .
T6526 11681-11683 IN denotes In
T6527 11684-11692 NN denotes contrast
T6528 11692-11693 , denotes ,
T6529 11694-11708 NN denotes overexpression
T6530 11709-11711 IN denotes of
T6531 11712-11713 DT denotes a
T6532 11714-11723 VBN denotes truncated
T6533 11724-11728 NNP denotes Sox6
T6534 11729-11736 NN denotes protein
T6535 11737-11741 WDT denotes that
T6536 11742-11747 VBZ denotes lacks
T6537 11748-11751 PRP$ denotes its
T6538 11752-11755 NNP denotes HMG
T6539 11756-11762 NN denotes domain
T6540 11763-11764 NNP denotes [
T6541 11764-11766 CD denotes 32
T6542 11766-11767 NNP denotes ]
T6543 11768-11769 -LRB- denotes (
T6544 11769-11776 JJ denotes similar
T6545 11777-11779 TO denotes to
T6546 11780-11783 DT denotes the
T6547 11784-11790 JJ denotes p 100H
T6548 11791-11796 NN denotes mouse
T6549 11797-11803 NN denotes allele
T6550 11803-11804 -RRB- denotes )
T6551 11805-11810 VBZ denotes fails
T6552 11811-11813 TO denotes to
T6553 11814-11821 VB denotes repress
T6554 11822-11827 JJ denotes E-Luc
T6555 11828-11836 NN denotes activity
T6556 11837-11838 -LRB- denotes (
T6557 11838-11844 NN denotes Figure
T6558 11845-11847 NN denotes 2B
T6559 11847-11848 -RRB- denotes )
T6560 11848-11849 . denotes .
T6561 11850-11855 DT denotes These
T6562 11856-11860 NNS denotes data
T6563 11861-11869 VBP denotes indicate
T6564 11870-11874 IN denotes that
T6565 11875-11879 JJ denotes Sox6
T6566 11880-11884 NNS denotes acts
T6567 11885-11887 TO denotes to
T6568 11888-11895 VB denotes repress
T6569 11896-11899 DT denotes the
T6570 11900-11902 JJ denotes ɛy
T6571 11903-11911 NN denotes promoter
T6572 11912-11914 IN denotes at
T6573 11915-11918 DT denotes the
T6574 11919-11934 JJ denotes transcriptional
T6575 11935-11940 NN denotes level
T6576 11940-11941 . denotes .
T6577 13323-13327 NNP denotes Sox6
T6578 13328-13331 VBZ denotes has
T6579 13332-13336 VBN denotes been
T6580 13337-13342 VBN denotes shown
T6581 13343-13345 TO denotes to
T6582 13346-13349 VB denotes act
T6583 13350-13352 IN denotes as
T6584 13353-13354 DT denotes a
T6585 13355-13364 NN denotes repressor
T6586 13365-13368 CC denotes and
T6587 13369-13371 TO denotes to
T6588 13372-13380 VB denotes interact
T6589 13381-13385 IN denotes with
T6590 13386-13387 DT denotes a
T6591 13388-13394 RB denotes widely
T6592 13395-13404 VBN denotes expressed
T6593 13405-13417 NN denotes co-repressor
T6594 13417-13418 , denotes ,
T6595 13419-13424 NNP denotes CtBP2
T6596 13424-13425 , denotes ,
T6597 13426-13428 IN denotes on
T6598 13429-13432 DT denotes the
T6599 13433-13438 JJ denotes fgf-3
T6600 13439-13447 NN denotes promoter
T6601 13448-13449 NN denotes [
T6602 13449-13450 CD denotes 5
T6603 13450-13451 NNP denotes ]
T6604 13451-13452 . denotes .
T6605 13453-13458 NNP denotes CtBP2
T6606 13459-13461 VBZ denotes is
T6607 13462-13471 VBN denotes expressed
T6608 13472-13474 IN denotes in
T6609 13475-13480 NNP denotes GM979
T6610 13481-13486 NNS denotes cells
T6611 13487-13488 -LRB- denotes (
T6612 13488-13499 JJ denotes unpublished
T6613 13500-13504 NNS denotes data
T6614 13504-13505 -RRB- denotes )
T6615 13505-13506 . denotes .
T6616 13507-13509 TO denotes To
T6617 13510-13521 VB denotes investigate
T6618 13522-13529 IN denotes whether
T6619 13530-13533 DT denotes the
T6620 13534-13545 NN denotes interaction
T6621 13546-13550 IN denotes with
T6622 13551-13556 NNP denotes CtBP2
T6623 13557-13559 VBZ denotes is
T6624 13560-13568 VBN denotes required
T6625 13569-13572 IN denotes for
T6626 13573-13577 JJ denotes Sox6
T6627 13578-13588 NN denotes repression
T6628 13589-13591 IN denotes of
T6629 13592-13595 DT denotes the
T6630 13596-13598 JJ denotes ɛy
T6631 13599-13607 NN denotes promoter
T6632 13607-13608 , denotes ,
T6633 13609-13611 PRP denotes we
T6634 13612-13622 VBD denotes introduced
T6635 13623-13624 DT denotes a
T6636 13625-13630 NN denotes point
T6637 13631-13639 NN denotes mutation
T6638 13640-13641 -LRB- denotes (
T6639 13641-13646 NNP denotes L386H
T6640 13646-13647 -RRB- denotes )
T6641 13648-13650 IN denotes in
T6642 13651-13654 DT denotes the
T6643 13655-13659 JJ denotes Sox6
T6644 13660-13667 NN denotes protein
T6645 13668-13672 WDT denotes that
T6646 13673-13676 VBZ denotes has
T6647 13677-13681 VBN denotes been
T6648 13682-13692 RB denotes previously
T6649 13693-13701 VBN denotes reported
T6650 13702-13704 TO denotes to
T6651 13705-13707 VB denotes be
T6652 13708-13718 JJ denotes sufficient
T6653 13719-13721 TO denotes to
T6654 13722-13729 VB denotes abolish
T6655 13730-13740 JJ denotes Sox6-CtBP2
T6656 13741-13752 NN denotes interaction
T6657 13753-13754 NN denotes [
T6658 13754-13755 CD denotes 5
T6659 13755-13756 NNP denotes ]
T6660 13756-13757 . denotes .
T6661 13758-13762 DT denotes This
T6662 13763-13768 JJ denotes amino
T6663 13769-13773 NN denotes acid
T6664 13774-13780 NN denotes change
T6665 13781-13783 VBZ denotes is
T6666 13784-13787 RB denotes not
T6667 13788-13790 IN denotes in
T6668 13791-13794 DT denotes the
T6669 13795-13798 NNP denotes HMG
T6670 13799-13802 NNP denotes DNA
T6671 13803-13810 JJ denotes binding
T6672 13811-13817 NN denotes domain
T6673 13817-13818 . denotes .
T6674 13819-13826 RB denotes However
T6675 13826-13827 , denotes ,
T6676 13828-13832 DT denotes this
T6677 13833-13839 JJ denotes mutant
T6678 13840-13847 NN denotes version
T6679 13848-13850 IN denotes of
T6680 13851-13855 JJ denotes Sox6
T6681 13856-13863 VBZ denotes retains
T6682 13864-13867 DT denotes the
T6683 13868-13875 NN denotes ability
T6684 13876-13878 TO denotes to
T6685 13879-13886 VB denotes repress
T6686 13887-13890 DT denotes the
T6687 13891-13893 JJ denotes ɛy
T6688 13894-13902 NN denotes promoter
T6689 13903-13905 IN denotes in
T6690 13906-13909 DT denotes the
T6691 13910-13922 NN denotes transfection
T6692 13923-13928 NN denotes assay
T6693 13929-13930 -LRB- denotes (
T6694 13930-13936 NN denotes Figure
T6695 13937-13939 NN denotes 2B
T6696 13939-13940 -RRB- denotes )
T6697 13940-13941 , denotes ,
T6698 13942-13952 VBG denotes indicating
T6699 13953-13957 IN denotes that
T6700 13958-13962 JJ denotes Sox6
T6701 13963-13972 NNS denotes represses
T6702 13973-13976 DT denotes the
T6703 13977-13979 JJ denotes ɛy
T6704 13980-13988 NN denotes promoter
T6705 13989-13991 IN denotes in
T6706 13992-13993 DT denotes a
T6707 13994-14011 JJ denotes CtBP2-independent
T6708 14012-14018 NN denotes manner
T6709 14018-14019 . denotes .
T6710 14020-14028 NN denotes Deletion
T6711 14029-14037 NN denotes analysis
T6712 14038-14040 IN denotes of
T6713 14041-14044 DT denotes the
T6714 14045-14047 JJ denotes ɛy
T6715 14048-14056 NN denotes promoter
T6716 14056-14057 , denotes ,
T6717 14058-14060 IN denotes as
T6718 14061-14066 VBN denotes shown
T6719 14067-14069 IN denotes in
T6720 14070-14076 NN denotes Figure
T6721 14077-14079 CD denotes 2C
T6722 14079-14080 , denotes ,
T6723 14081-14088 VBD denotes defined
T6724 14089-14090 DT denotes a
T6725 14091-14097 NN denotes region
T6726 14098-14099 -LRB- denotes (
T6727 14099-14100 FW denotes −
T6728 14100-14102 CD denotes 63
T6729 14103-14105 TO denotes to
T6730 14106-14107 CD denotes −
T6731 14107-14109 CD denotes 37
T6732 14109-14110 -RRB- denotes )
T6733 14111-14117 IN denotes within
T6734 14118-14121 DT denotes the
T6735 14122-14124 JJ denotes ɛy
T6736 14125-14133 JJ denotes proximal
T6737 14134-14142 NN denotes promoter
T6738 14143-14147 WDT denotes that
T6739 14148-14150 VBZ denotes is
T6740 14151-14159 JJ denotes critical
T6741 14160-14163 IN denotes for
T6742 14164-14168 JJ denotes Sox6
T6743 14169-14179 NN denotes repression
T6744 14179-14180 . denotes .
T6745 14181-14189 NN denotes Analysis
T6746 14190-14192 IN denotes of
T6747 14193-14197 DT denotes this
T6748 14198-14203 JJ denotes short
T6749 14204-14210 NN denotes region
T6750 14211-14218 VBZ denotes reveals
T6751 14219-14222 CD denotes two
T6752 14223-14231 JJ denotes Sox/Sox6
T6753 14232-14241 NN denotes consensus
T6754 14242-14249 JJ denotes binding
T6755 14250-14255 NNS denotes sites
T6756 14256-14257 VBP denotes [
T6757 14257-14258 CD denotes 5
T6758 14258-14259 NNP denotes ]
T6759 14260-14261 -LRB- denotes (
T6760 14261-14267 NNP denotes Figure
T6761 14268-14270 NNP denotes 3A
T6762 14270-14271 -RRB- denotes )
T6763 14271-14272 . denotes .
T8140 16841-16845 NNP denotes EMSA
T8141 16846-16849 CC denotes and
T8142 16850-16854 NNP denotes ChIP
T8143 16855-16861 NNP denotes Assays
T8144 16862-16866 NNP denotes Show
T8145 16867-16871 IN denotes that
T8146 16872-16876 NNP denotes Sox6
T8147 16877-16885 RB denotes Directly
T8148 16886-16891 VBZ denotes Binds
T8149 16892-16894 TO denotes to
T8150 16895-16898 DT denotes the
T8151 16899-16901 NN denotes ɛy
T8152 16902-16910 NNP denotes Promoter
T8153 16911-16915 NNP denotes Sox6
T8154 16916-16921 MD denotes might
T8155 16922-16929 VB denotes repress
T8156 16930-16933 DT denotes the
T8157 16934-16936 JJ denotes ɛy
T8158 16937-16945 NN denotes promoter
T8159 16945-16946 , denotes ,
T8160 16947-16953 CC denotes either
T8161 16954-16961 IN denotes through
T8162 16962-16968 JJ denotes direct
T8163 16969-16977 JJ denotes physical
T8164 16978-16985 NN denotes contact
T8165 16986-16990 IN denotes with
T8166 16991-16994 DT denotes the
T8167 16995-17003 NN denotes promoter
T8168 17004-17006 CC denotes or
T8169 17007-17009 IN denotes by
T8170 17010-17020 VBG denotes regulating
T8171 17021-17034 NNS denotes intermediates
T8172 17035-17044 VBG denotes affecting
T8173 17045-17048 DT denotes the
T8174 17049-17051 JJ denotes ɛy
T8175 17052-17060 NN denotes promoter
T8176 17060-17061 . denotes .
T8177 17062-17064 TO denotes To
T8178 17065-17076 VB denotes investigate
T8179 17077-17084 IN denotes whether
T8180 17085-17089 NNP denotes Sox6
T8181 17090-17092 VBZ denotes is
T8182 17093-17101 RB denotes directly
T8183 17102-17112 VBN denotes associated
T8184 17113-17117 IN denotes with
T8185 17118-17121 DT denotes the
T8186 17122-17124 JJ denotes ɛy
T8187 17125-17133 NN denotes promoter
T8188 17133-17134 , denotes ,
T8189 17135-17137 PRP denotes we
T8190 17138-17143 RB denotes first
T8191 17144-17153 VBD denotes performed
T8192 17154-17169 JJ denotes electrophoretic
T8193 17170-17178 NN denotes mobility
T8194 17179-17184 NN denotes shift
T8195 17185-17191 NNS denotes assays
T8196 17192-17193 -LRB- denotes (
T8197 17193-17197 NNP denotes EMSA
T8198 17197-17198 -RRB- denotes )
T8199 17199-17204 VBG denotes using
T8200 17205-17206 DT denotes a
T8201 17207-17219 JJ denotes c-Myc-tagged
T8202 17220-17224 NN denotes Sox6
T8203 17225-17227 IN denotes in
T8204 17228-17229 DT denotes a
T8205 17230-17242 NN denotes reticulocyte
T8206 17243-17255 JJ denotes lysate-based
T8207 17256-17281 NN denotes transcription/translation
T8208 17282-17284 IN denotes in
T8209 17285-17290 NN denotes vitro
T8210 17291-17297 NN denotes system
T8211 17297-17298 . denotes .
T8212 17299-17302 DT denotes The
T8213 17303-17309 NNS denotes probes
T8214 17310-17314 VBN denotes used
T8215 17315-17318 VBP denotes are
T8216 17319-17325 VBN denotes listed
T8217 17326-17328 IN denotes in
T8218 17329-17335 NN denotes Figure
T8219 17336-17338 NN denotes 3A
T8220 17338-17339 . denotes .
T8221 17340-17343 DT denotes The
T8222 17344-17346 CD denotes 36
T8223 17347-17351 NN denotes base
T8224 17352-17356 NN denotes pair
T8225 17357-17358 -LRB- denotes (
T8226 17358-17360 NN denotes bp
T8227 17360-17361 -RRB- denotes )
T8228 17362-17364 NN denotes WT
T8229 17365-17370 NN denotes probe
T8230 17371-17382 NNS denotes corresponds
T8231 17383-17385 TO denotes to
T8232 17386-17389 DT denotes the
T8233 17390-17398 JJ denotes critical
T8234 17399-17405 NN denotes region
T8235 17406-17408 IN denotes of
T8236 17409-17412 DT denotes the
T8237 17413-17415 JJ denotes ɛy
T8238 17416-17424 NN denotes promoter
T8239 17425-17432 VBN denotes defined
T8240 17433-17435 IN denotes in
T8241 17436-17439 PRP$ denotes our
T8242 17440-17448 NN denotes promoter
T8243 17449-17457 NN denotes deletion
T8244 17458-17466 NNS denotes analyses
T8245 17466-17467 . denotes .
T8246 17468-17472 DT denotes This
T8247 17473-17478 NN denotes probe
T8248 17479-17487 VBZ denotes contains
T8249 17488-17491 CD denotes two
T8250 17492-17501 NN denotes consensus
T8251 17502-17510 NNP denotes Sox/Sox6
T8252 17511-17518 JJ denotes binding
T8253 17519-17524 NNS denotes sites
T8254 17524-17525 . denotes .
T8255 17526-17530 RB denotes Also
T8256 17531-17539 VBN denotes included
T8257 17540-17542 IN denotes in
T8258 17543-17546 PRP$ denotes our
T8259 17547-17551 NNP denotes EMSA
T8260 17552-17555 VBP denotes are
T8261 17556-17561 CD denotes three
T8262 17562-17569 VBN denotes mutated
T8263 17570-17576 NNS denotes probes
T8264 17577-17581 WDT denotes that
T8265 17582-17585 VBP denotes are
T8266 17585-17586 , denotes ,
T8267 17587-17593 CC denotes either
T8268 17594-17603 VBN denotes truncated
T8269 17604-17605 -LRB- denotes (
T8270 17605-17607 CD denotes M1
T8271 17607-17608 -RRB- denotes )
T8272 17608-17609 , denotes ,
T8273 17610-17612 CC denotes or
T8274 17613-17620 VBN denotes mutated
T8275 17621-17622 -LRB- denotes (
T8276 17622-17624 CD denotes M2
T8277 17625-17628 CC denotes and
T8278 17629-17631 CD denotes M3
T8279 17631-17632 -RRB- denotes )
T8280 17633-17635 IN denotes in
T8281 17636-17644 NNP denotes Sox/Sox6
T8282 17645-17652 JJ denotes binding
T8283 17653-17658 NNS denotes sites
T8284 17659-17660 -LRB- denotes (
T8285 17660-17666 NN denotes Figure
T8286 17667-17669 NN denotes 3A
T8287 17669-17670 -RRB- denotes )
T8288 17670-17671 . denotes .
T8289 17672-17676 NNP denotes Sox6
T8290 17677-17679 VBZ denotes is
T8291 17680-17684 JJ denotes able
T8292 17685-17687 TO denotes to
T8293 17688-17698 RB denotes physically
T8294 17699-17708 JJ denotes associate
T8295 17709-17713 IN denotes with
T8296 17714-17717 DT denotes the
T8297 17718-17723 JJ denotes 36-bp
T8298 17724-17730 NN denotes region
T8299 17731-17732 -LRB- denotes (
T8300 17732-17738 NN denotes Figure
T8301 17739-17741 NN denotes 3B
T8302 17741-17742 -RRB- denotes )
T8303 17743-17749 IN denotes within
T8304 17750-17753 DT denotes the
T8305 17754-17756 JJ denotes ɛy
T8306 17757-17765 NN denotes promoter
T8307 17766-17773 VBN denotes defined
T8308 17774-17776 IN denotes by
T8309 17777-17780 DT denotes the
T8310 17781-17789 NN denotes deletion
T8311 17790-17798 NN denotes analysis
T8312 17799-17810 NNS denotes experiments
T8313 17811-17812 -LRB- denotes (
T8314 17812-17818 NN denotes Figure
T8315 17819-17821 CD denotes 2C
T8316 17821-17822 -RRB- denotes )
T8317 17822-17823 . denotes .
T8318 17824-17827 DT denotes The
T8319 17828-17833 JJ denotes 36-bp
T8320 17834-17839 NN denotes probe
T8321 17840-17843 VBD denotes was
T8322 17844-17851 VBN denotes shifted
T8323 17852-17854 IN denotes by
T8324 17855-17858 DT denotes the
T8325 17859-17865 VBN denotes tagged
T8326 17866-17870 NNP denotes Sox6
T8327 17871-17878 NN denotes protein
T8328 17878-17879 . denotes .
T8329 17880-17888 RB denotes Moreover
T8330 17888-17889 , denotes ,
T8331 17890-17894 DT denotes both
T8332 17895-17900 JJ denotes c-Myc
T8333 17901-17904 CC denotes and
T8334 17905-17909 JJ denotes Sox6
T8335 17910-17920 NNS denotes antibodies
T8336 17921-17931 VBP denotes supershift
T8337 17932-17935 DT denotes the
T8338 17936-17940 NN denotes band
T8339 17940-17941 , denotes ,
T8340 17942-17952 VBG denotes indicating
T8341 17953-17957 IN denotes that
T8342 17958-17961 DT denotes the
T8343 17962-17969 JJ denotes binding
T8344 17970-17972 VBZ denotes is
T8345 17973-17986 JJ denotes Sox6-specific
T8346 17986-17987 . denotes .
T8347 17988-17990 TO denotes To
T8348 17991-17995 VB denotes rule
T8349 17996-17999 RP denotes out
T8350 18000-18003 DT denotes the
T8351 18004-18015 NN denotes possibility
T8352 18016-18020 IN denotes that
T8353 18021-18024 DT denotes the
T8354 18025-18030 JJ denotes c-Myc
T8355 18031-18034 NN denotes tag
T8356 18035-18041 PRP denotes itself
T8357 18042-18047 VBZ denotes binds
T8358 18048-18050 TO denotes to
T8359 18051-18054 DT denotes the
T8360 18055-18060 NN denotes probe
T8361 18060-18061 , denotes ,
T8362 18062-18064 DT denotes an
T8363 18065-18074 JJ denotes HA-tagged
T8364 18075-18079 NN denotes Sox6
T8365 18080-18083 VBD denotes was
T8366 18084-18088 VBN denotes used
T8367 18089-18091 IN denotes in
T8368 18092-18099 DT denotes another
T8369 18100-18104 NNP denotes EMSA
T8370 18105-18109 WDT denotes that
T8371 18110-18119 VBD denotes confirmed
T8372 18120-18125 DT denotes these
T8373 18126-18133 NNS denotes results
T8374 18134-18135 -LRB- denotes (
T8375 18135-18141 NN denotes Figure
T8376 18142-18144 NN denotes 3C
T8377 18144-18145 -RRB- denotes )
T8378 18145-18146 . denotes .
T8379 18147-18151 JJ denotes Next
T8380 18151-18152 , denotes ,
T8381 18153-18160 JJ denotes nuclear
T8382 18161-18169 NNS denotes extracts
T8383 18170-18174 IN denotes from
T8384 18175-18178 NNP denotes MEL
T8385 18179-18184 NNS denotes cells
T8386 18185-18189 VBD denotes were
T8387 18190-18194 VBN denotes used
T8388 18195-18197 IN denotes in
T8389 18198-18202 NNP denotes EMSA
T8390 18203-18212 VBG denotes employing
T8391 18213-18216 DT denotes the
T8392 18217-18221 JJ denotes same
T8393 18222-18227 JJ denotes 36-bp
T8394 18228-18233 NN denotes probe
T8395 18233-18234 . denotes .
T8396 18235-18238 NNP denotes MEL
T8397 18239-18244 NNS denotes cells
T8398 18244-18245 , denotes ,
T8399 18246-18247 DT denotes a
T8400 18248-18254 JJ denotes murine
T8401 18255-18270 JJ denotes erythroleukemic
T8402 18271-18275 NN denotes cell
T8403 18276-18280 NN denotes line
T8404 18280-18281 , denotes ,
T8405 18282-18289 JJ denotes express
T8406 18290-18295 NN denotes adult
T8407 18296-18297 NN denotes β
T8408 18298-18305 NNS denotes globins
T8409 18305-18306 , denotes ,
T8410 18307-18310 CC denotes but
T8411 18311-18314 RB denotes not
T8412 18315-18317 VB denotes ɛy
T8413 18318-18319 NNP denotes [
T8414 18319-18321 CD denotes 33
T8415 18321-18322 NNP denotes ]
T8416 18322-18323 . denotes .
T8417 18324-18328 JJ denotes Sox6
T8418 18329-18337 RB denotes directly
T8419 18338-18343 VBZ denotes binds
T8420 18344-18346 TO denotes to
T8421 18347-18351 DT denotes this
T8422 18352-18355 NN denotes DNA
T8423 18356-18364 NN denotes sequence
T8424 18365-18367 IN denotes in
T8425 18368-18371 NNP denotes MEL
T8426 18372-18377 NNS denotes cells
T8427 18378-18379 -LRB- denotes (
T8428 18379-18385 NN denotes Figure
T8429 18386-18388 CD denotes 3D
T8430 18388-18389 -RRB- denotes )
T8431 18389-18390 . denotes .
T8432 18391-18394 DT denotes The
T8433 18395-18401 JJ denotes intact
T8434 18402-18411 NN denotes consensus
T8435 18412-18420 NNP denotes Sox/Sox6
T8436 18421-18428 JJ denotes binding
T8437 18429-18434 NNS denotes sites
T8438 18435-18437 IN denotes of
T8439 18438-18441 DT denotes the
T8440 18442-18445 NNP denotes DNA
T8441 18446-18451 NN denotes probe
T8442 18452-18455 VBP denotes are
T8443 18456-18464 VBN denotes required
T8444 18465-18468 IN denotes for
T8445 18469-18472 DT denotes the
T8446 18473-18480 JJ denotes binding
T8447 18480-18481 , denotes ,
T8448 18482-18484 IN denotes as
T8449 18485-18490 VBN denotes shown
T8450 18491-18493 IN denotes in
T8451 18494-18497 DT denotes the
T8452 18498-18509 NN denotes competition
T8453 18510-18515 NN denotes assay
T8454 18516-18517 -LRB- denotes (
T8455 18517-18523 NN denotes Figure
T8456 18524-18526 CD denotes 3E
T8457 18526-18527 -RRB- denotes )
T8458 18527-18528 . denotes .
T8459 18529-18537 NNP denotes Ablation
T8460 18538-18540 IN denotes of
T8461 18541-18549 JJ denotes putative
T8462 18550-18558 NNP denotes Sox/Sox6
T8463 18559-18566 JJ denotes binding
T8464 18567-18572 NNS denotes sites
T8465 18573-18574 -LRB- denotes (
T8466 18574-18576 CD denotes M1
T8467 18577-18580 CC denotes and
T8468 18581-18583 CD denotes M3
T8469 18583-18584 -RRB- denotes )
T8470 18585-18592 VBP denotes abolish
T8471 18593-18598 PRP$ denotes their
T8472 18599-18606 NN denotes ability
T8473 18607-18609 TO denotes to
T8474 18610-18617 VB denotes compete
T8475 18618-18620 IN denotes in
T8476 18621-18625 NNP denotes EMSA
T8477 18626-18627 -LRB- denotes (
T8478 18627-18633 NNP denotes Figure
T8479 18634-18636 NNP denotes 3E
T8480 18636-18637 -RRB- denotes )
T8481 18637-18638 . denotes .
T8482 18639-18642 DT denotes The
T8483 18643-18645 NNP denotes M2
T8484 18646-18652 JJ denotes mutant
T8485 18653-18658 NN denotes probe
T8486 18659-18662 MD denotes may
T8487 18663-18670 VB denotes compete
T8488 18671-18680 RB denotes partially
T8489 18681-18685 IN denotes with
T8490 18686-18688 NNP denotes WT
T8491 18689-18696 JJ denotes binding
T8492 18696-18697 . denotes .
T8493 18698-18700 TO denotes To
T8494 18701-18712 VB denotes investigate
T8495 18713-18716 DT denotes the
T8496 18717-18727 JJ denotes functional
T8497 18728-18740 NN denotes significance
T8498 18741-18743 IN denotes of
T8499 18744-18747 DT denotes the
T8500 18748-18754 JJ denotes intact
T8501 18755-18763 NNP denotes Sox/Sox6
T8502 18764-18771 JJ denotes binding
T8503 18772-18777 NNS denotes sites
T8504 18777-18778 , denotes ,
T8505 18779-18782 DT denotes the
T8506 18783-18785 JJ denotes ɛy
T8507 18786-18794 NN denotes promoter
T8508 18795-18803 NN denotes reporter
T8509 18804-18814 NNS denotes constructs
T8510 18815-18819 IN denotes with
T8511 18820-18831 VBN denotes mutagenized
T8512 18832-18840 NNP denotes Sox/Sox6
T8513 18841-18848 JJ denotes binding
T8514 18849-18854 NNS denotes sites
T8515 18855-18859 VBD denotes were
T8516 18860-18874 VBN denotes co-transfected
T8517 18875-18879 IN denotes with
T8518 18880-18883 DT denotes the
T8519 18884-18888 JJ denotes Sox6
T8520 18889-18903 NN denotes overexpression
T8521 18904-18910 NN denotes vector
T8522 18911-18915 IN denotes into
T8523 18916-18921 NNP denotes GM979
T8524 18922-18927 NNS denotes cells
T8525 18927-18928 . denotes .
T8526 18929-18939 JJ denotes Consistent
T8527 18940-18944 IN denotes with
T8528 18945-18948 DT denotes the
T8529 18949-18953 NNP denotes EMSA
T8530 18954-18961 NNS denotes results
T8531 18961-18962 , denotes ,
T8532 18963-18966 DT denotes the
T8533 18967-18973 JJ denotes mutant
T8534 18974-18976 NN denotes ɛy
T8535 18977-18985 NN denotes promoter
T8536 18986-18994 NN denotes reporter
T8537 18995-19005 NNS denotes constructs
T8538 19006-19007 -LRB- denotes (
T8539 19007-19011 IN denotes with
T8540 19012-19018 DT denotes either
T8541 19019-19022 CD denotes one
T8542 19023-19025 CC denotes or
T8543 19026-19030 DT denotes both
T8544 19031-19039 JJ denotes Sox/Sox6
T8545 19040-19047 JJ denotes binding
T8546 19048-19053 NNS denotes sites
T8547 19054-19065 VBN denotes mutagenized
T8548 19065-19066 -RRB- denotes )
T8549 19067-19069 VBP denotes do
T8550 19070-19073 RB denotes not
T8551 19074-19080 VB denotes result
T8552 19081-19083 IN denotes in
T8553 19084-19095 JJ denotes significant
T8554 19096-19104 NN denotes promoter
T8555 19105-19115 NN denotes repression
T8556 19116-19118 IN denotes in
T8557 19119-19131 NN denotes transfection
T8558 19132-19139 NNS denotes studies
T8559 19140-19141 -LRB- denotes (
T8560 19141-19147 NN denotes Figure
T8561 19148-19150 CD denotes 3F
T8562 19150-19151 -RRB- denotes )
T8563 19151-19152 . denotes .
T8564 19153-19157 RB denotes Thus
T8565 19157-19158 , denotes ,
T8566 19159-19163 DT denotes both
T8567 19164-19169 NNS denotes sites
T8568 19170-19173 VBP denotes are
T8569 19174-19182 VBN denotes required
T8570 19183-19186 IN denotes for
T8571 19187-19194 JJ denotes maximal
T8572 19195-19205 NN denotes repression
T8573 19206-19208 IN denotes of
T8574 19209-19211 NN denotes ɛy
T8575 19212-19214 IN denotes by
T8576 19215-19219 NNP denotes Sox6
T8577 19219-19220 , denotes ,
T8578 19221-19224 CC denotes but
T8579 19225-19228 RB denotes not
T8580 19229-19231 TO denotes to
T8581 19232-19235 DT denotes the
T8582 19236-19240 JJ denotes same
T8583 19241-19247 NN denotes degree
T8584 19247-19248 . denotes .
T8585 19249-19251 PRP denotes We
T8586 19252-19256 RB denotes also
T8587 19257-19263 VBD denotes tested
T8588 19264-19271 IN denotes whether
T8589 19272-19276 JJ denotes Sox6
T8590 19277-19282 NNS denotes binds
T8591 19283-19285 TO denotes to
T8592 19286-19289 DT denotes the
T8593 19290-19292 JJ denotes ɛy
T8594 19293-19301 NN denotes promoter
T8595 19302-19304 IN denotes in
T8596 19305-19309 NN denotes vivo
T8597 19310-19315 VBG denotes using
T8598 19316-19325 NN denotes chromatin
T8599 19326-19345 NN denotes immunoprecipitation
T8600 19346-19347 -LRB- denotes (
T8601 19347-19351 NNP denotes ChIP
T8602 19351-19352 -RRB- denotes )
T8603 19353-19354 -LRB- denotes (
T8604 19354-19360 NN denotes Figure
T8605 19361-19362 CD denotes 4
T8606 19362-19363 -RRB- denotes )
T8607 19363-19364 . denotes .
T8608 19365-19368 DT denotes The
T8609 19369-19384 JJ denotes Sox6-containing
T8610 19385-19392 NN denotes complex
T8611 19393-19396 VBD denotes was
T8612 19397-19415 VBN denotes immunoprecipitated
T8613 19416-19420 IN denotes from
T8614 19421-19424 NNP denotes MEL
T8615 19425-19430 NNS denotes cells
T8616 19431-19433 CC denotes or
T8617 19434-19438 IN denotes from
T8618 19439-19444 NN denotes liver
T8619 19445-19450 NNS denotes cells
T8620 19451-19453 IN denotes of
T8621 19454-19458 CD denotes 15.5
T8622 19459-19462 NN denotes dpc
T8623 19463-19465 NNP denotes WT
T8624 19466-19470 NNS denotes mice
T8625 19471-19476 VBG denotes using
T8626 19477-19481 JJ denotes Sox6
T8627 19482-19490 NN denotes antibody
T8628 19490-19491 . denotes .
T8629 19492-19498 NN denotes Figure
T8630 19499-19500 CD denotes 4
T8631 19501-19506 NNS denotes shows
T8632 19507-19511 IN denotes that
T8633 19512-19515 DT denotes the
T8634 19516-19518 JJ denotes ɛy
T8635 19519-19527 JJ denotes proximal
T8636 19528-19536 NN denotes promoter
T8637 19537-19539 VBZ denotes is
T8638 19540-19547 RB denotes readily
T8639 19548-19566 VBN denotes immunoprecipitated
T8640 19567-19571 IN denotes with
T8641 19572-19576 JJ denotes Sox6
T8642 19577-19585 NN denotes antibody
T8643 19586-19588 IN denotes in
T8644 19589-19593 DT denotes both
T8645 19594-19597 NNP denotes MEL
T8646 19598-19603 NNS denotes cells
T8647 19604-19607 CC denotes and
T8648 19608-19613 NN denotes liver
T8649 19614-19619 NNS denotes cells
T8650 19619-19620 . denotes .
T8651 19621-19627 JJ denotes Normal
T8652 19628-19631 NNP denotes IgG
T8653 19632-19635 VBD denotes was
T8654 19636-19640 VBN denotes used
T8655 19641-19643 IN denotes as
T8656 19644-19645 DT denotes a
T8657 19646-19654 JJ denotes negative
T8658 19655-19662 NN denotes control
T8659 19663-19664 -LRB- denotes (
T8660 19664-19670 NN denotes Figure
T8661 19671-19673 NN denotes 4A
T8662 19673-19674 -RRB- denotes )
T8663 19674-19675 . denotes .
T8664 19676-19679 DT denotes The
T8665 19680-19685 IN denotes above
T8666 19686-19690 NNS denotes data
T8667 19691-19692 -LRB- denotes (
T8668 19692-19699 NNS denotes Figures
T8669 19700-19701 CD denotes 3
T8670 19702-19705 CC denotes and
T8671 19706-19707 CD denotes 4
T8672 19707-19708 -RRB- denotes )
T8673 19709-19716 RB denotes clearly
T8674 19717-19725 VBP denotes indicate
T8675 19726-19730 IN denotes that
T8676 19731-19735 JJ denotes Sox6
T8677 19736-19740 NNS denotes acts
T8678 19741-19743 IN denotes as
T8679 19744-19745 DT denotes a
T8680 19746-19755 NN denotes repressor
T8681 19756-19758 IN denotes of
T8682 19759-19762 DT denotes the
T8683 19763-19765 JJ denotes ɛy
T8684 19766-19770 NN denotes gene
T8685 19771-19773 IN denotes by
T8686 19774-19782 RB denotes directly
T8687 19783-19790 JJ denotes binding
T8688 19791-19793 TO denotes to
T8689 19794-19797 DT denotes the
T8690 19798-19800 JJ denotes ɛy
T8691 19801-19809 NN denotes promoter
T8692 19809-19810 , denotes ,
T8693 19811-19819 RB denotes probably
T8694 19820-19822 IN denotes as
T8695 19823-19824 DT denotes a
T8696 19825-19830 NN denotes dimer
T8697 19830-19831 . denotes .
T9421 20660-20663 DT denotes The
T9422 20664-20674 NNP denotes Persistent
T9423 20675-20685 NNP denotes Expression
T9424 20686-20688 IN denotes of
T9425 20689-20691 NNP denotes ɛy
T9426 20692-20698 NNP denotes Globin
T9427 20699-20701 IN denotes in
T9428 20702-20716 NNP denotes Sox6-Deficient
T9429 20717-20721 NNP denotes Mice
T9430 20722-20724 VBZ denotes Is
T9431 20725-20728 JJ denotes Due
T9432 20729-20731 TO denotes to
T9433 20732-20733 DT denotes a
T9434 20734-20740 NN denotes Defect
T9435 20741-20743 IN denotes in
T9436 20744-20747 DT denotes the
T9437 20748-20755 JJ denotes ɛy-Gene
T9438 20756-20765 VBG denotes Silencing
T9439 20766-20775 NNP denotes Mechanism
T9440 20776-20778 IN denotes in
T9441 20779-20789 NNP denotes Definitive
T9442 20790-20799 NNP denotes Erythroid
T9443 20800-20805 NNP denotes Cells
T9444 20806-20814 NNP denotes Normally
T9445 20814-20815 , denotes ,
T9446 20816-20819 DT denotes the
T9447 20820-20822 JJ denotes ɛy
T9448 20823-20829 NN denotes globin
T9449 20830-20834 NN denotes gene
T9450 20835-20837 VBZ denotes is
T9451 20838-20849 RB denotes exclusively
T9452 20850-20859 VBN denotes expressed
T9453 20860-20862 IN denotes in
T9454 20863-20872 JJ denotes primitive
T9455 20873-20885 NNS denotes erythrocytes
T9456 20886-20889 CC denotes and
T9457 20890-20898 VBN denotes silenced
T9458 20899-20901 IN denotes in
T9459 20902-20912 JJ denotes definitive
T9460 20913-20925 NNS denotes erythrocytes
T9461 20925-20926 . denotes .
T9462 20927-20929 TO denotes To
T9463 20930-20939 VB denotes determine
T9464 20940-20947 IN denotes whether
T9465 20948-20951 DT denotes the
T9466 20952-20962 JJ denotes persistent
T9467 20963-20973 NN denotes expression
T9468 20974-20976 IN denotes of
T9469 20977-20979 JJ denotes ɛy
T9470 20980-20986 NN denotes globin
T9471 20987-20989 VBZ denotes is
T9472 20990-20993 JJ denotes due
T9473 20994-20996 TO denotes to
T9474 20997-21005 JJ denotes residual
T9475 21006-21015 JJ denotes primitive
T9476 21016-21028 NNS denotes erythrocytes
T9477 21029-21031 CC denotes or
T9478 21032-21034 VBZ denotes is
T9479 21035-21038 JJ denotes due
T9480 21039-21041 TO denotes to
T9481 21042-21049 JJ denotes ectopic
T9482 21050-21060 NN denotes expression
T9483 21061-21063 IN denotes of
T9484 21064-21066 JJ denotes ɛy
T9485 21067-21073 NN denotes globin
T9486 21074-21076 IN denotes in
T9487 21077-21087 JJ denotes definitive
T9488 21088-21100 NNS denotes erythrocytes
T9489 21100-21101 , denotes ,
T9490 21102-21104 PRP denotes we
T9491 21105-21113 VBD denotes examined
T9492 21114-21117 DT denotes the
T9493 21118-21125 JJ denotes spatial
T9494 21126-21133 NN denotes pattern
T9495 21134-21136 IN denotes of
T9496 21137-21139 JJ denotes ɛy
T9497 21140-21146 NN denotes globin
T9498 21147-21158 NNS denotes transcripts
T9499 21159-21161 IN denotes in
T9500 21162-21167 NN denotes mouse
T9501 21168-21175 NNS denotes embryos
T9502 21176-21178 IN denotes by
T9503 21179-21181 IN denotes in
T9504 21182-21186 NN denotes situ
T9505 21187-21200 NN denotes hybridization
T9506 21201-21202 -LRB- denotes (
T9507 21202-21208 NN denotes Figure
T9508 21209-21210 CD denotes 5
T9509 21210-21211 -RRB- denotes )
T9510 21211-21212 . denotes .
T9511 21213-21215 IN denotes As
T9512 21216-21224 VBN denotes expected
T9513 21224-21225 , denotes ,
T9514 21226-21228 JJ denotes ɛy
T9515 21229-21235 NN denotes globin
T9516 21236-21238 VBZ denotes is
T9517 21239-21242 RB denotes not
T9518 21243-21252 VBN denotes expressed
T9519 21253-21255 IN denotes in
T9520 21256-21259 DT denotes the
T9521 21260-21262 NNP denotes WT
T9522 21263-21271 JJ denotes 14.5-dpc
T9523 21272-21277 NN denotes liver
T9524 21277-21278 , denotes ,
T9525 21279-21282 DT denotes the
T9526 21283-21287 NN denotes site
T9527 21288-21290 IN denotes of
T9528 21291-21301 JJ denotes definitive
T9529 21302-21316 NNS denotes erythropoiesis
T9530 21317-21319 IN denotes in
T9531 21320-21323 DT denotes the
T9532 21324-21329 NN denotes fetus
T9533 21329-21330 . denotes .
T9534 21331-21333 IN denotes In
T9535 21334-21342 NN denotes contrast
T9536 21342-21343 , denotes ,
T9537 21344-21352 JJ denotes abundant
T9538 21353-21360 JJ denotes ectopic
T9539 21361-21363 NN denotes ɛy
T9540 21364-21368 NNP denotes mRNA
T9541 21369-21379 NN denotes expression
T9542 21380-21382 VBZ denotes is
T9543 21383-21387 VBN denotes seen
T9544 21388-21390 IN denotes in
T9545 21391-21394 DT denotes the
T9546 21395-21400 NN denotes liver
T9547 21401-21403 IN denotes of
T9548 21404-21412 JJ denotes 14.5-dpc
T9549 21413-21420 NNS denotes mutants
T9550 21421-21422 -LRB- denotes (
T9551 21422-21428 NN denotes Figure
T9552 21429-21430 CD denotes 5
T9553 21431-21432 DT denotes A
T9554 21433-21434 NNP denotes D
T9555 21434-21435 -RRB- denotes )
T9556 21435-21436 . denotes .
T9557 21437-21444 RB denotes However
T9558 21444-21445 , denotes ,
T9559 21446-21449 DT denotes the
T9560 21450-21460 NN denotes expression
T9561 21461-21463 IN denotes of
T9562 21464-21468 NN denotes βmaj
T9563 21468-21469 NN denotes /
T9564 21469-21472 NN denotes min
T9565 21473-21479 NN denotes globin
T9566 21480-21482 VBZ denotes is
T9567 21483-21490 RB denotes equally
T9568 21491-21499 JJ denotes abundant
T9569 21500-21502 IN denotes in
T9570 21503-21507 DT denotes both
T9571 21508-21510 NNP denotes WT
T9572 21511-21514 CC denotes and
T9573 21515-21520 NNP denotes p100H
T9574 21521-21527 JJ denotes mutant
T9575 21528-21532 NNS denotes mice
T9576 21533-21534 -LRB- denotes (
T9577 21534-21540 NN denotes Figure
T9578 21541-21542 CD denotes 5
T9579 21543-21544 NNP denotes E
T9580 21545-21548 CC denotes and
T9581 21549-21550 NN denotes F
T9582 21550-21551 -RRB- denotes )
T9583 21551-21552 . denotes .
T9584 21553-21558 DT denotes These
T9585 21559-21563 NNS denotes data
T9586 21564-21575 VBP denotes demonstrate
T9587 21576-21580 IN denotes that
T9588 21581-21584 DT denotes the
T9589 21585-21595 JJ denotes persistent
T9590 21596-21600 JJ denotes high
T9591 21601-21607 NNS denotes levels
T9592 21608-21610 IN denotes of
T9593 21611-21613 NN denotes ɛy
T9594 21614-21617 VBP denotes are
T9595 21618-21621 JJ denotes due
T9596 21622-21624 TO denotes to
T9597 21625-21632 JJ denotes ectopic
T9598 21633-21643 NN denotes expression
T9599 21644-21646 IN denotes in
T9600 21647-21650 DT denotes the
T9601 21651-21661 JJ denotes definitive
T9602 21662-21671 JJ denotes erythroid
T9603 21672-21677 NNS denotes cells
T9604 21678-21682 WDT denotes that
T9605 21683-21689 VBP denotes mature
T9606 21690-21692 IN denotes in
T9607 21693-21696 DT denotes the
T9608 21697-21702 JJ denotes fetal
T9609 21703-21708 NN denotes liver
T9610 21708-21709 , denotes ,
T9611 21710-21720 VBG denotes suggesting
T9612 21721-21725 IN denotes that
T9613 21726-21731 EX denotes there
T9614 21732-21734 VBZ denotes is
T9615 21735-21737 DT denotes an
T9616 21738-21747 JJ denotes intrinsic
T9617 21748-21754 NN denotes defect
T9618 21755-21757 IN denotes of
T9619 21758-21761 DT denotes the
T9620 21762-21764 NN denotes ɛy
T9621 21765-21774 VBG denotes silencing
T9622 21775-21784 NN denotes mechanism
T9623 21785-21787 IN denotes in
T9624 21788-21797 JJ denotes Sox6-null
T9625 21798-21802 NNS denotes mice
T9626 21802-21803 . denotes .
T10094 22433-22436 DT denotes The
T10095 22437-22447 NNP denotes Expression
T10096 22448-22455 NNP denotes Pattern
T10097 22456-22458 IN denotes of
T10098 22459-22463 NNP denotes Sox6
T10099 22464-22472 VBZ denotes Suggests
T10100 22473-22474 DT denotes a
T10101 22475-22479 NN denotes Role
T10102 22480-22482 IN denotes in
T10103 22483-22493 JJ denotes Definitive
T10104 22494-22508 NNPS denotes Erythropoiesis
T10105 22509-22512 DT denotes The
T10106 22513-22524 NN denotes observation
T10107 22525-22529 WDT denotes that
T10108 22530-22544 JJ denotes Sox6-deficient
T10109 22545-22549 NNS denotes mice
T10110 22550-22561 RB denotes ectopically
T10111 22562-22569 VBP denotes express
T10112 22570-22572 JJ denotes ɛy
T10113 22573-22579 NN denotes globin
T10114 22580-22582 IN denotes in
T10115 22583-22588 NN denotes liver
T10116 22588-22589 , denotes ,
T10117 22590-22595 WRB denotes where
T10118 22596-22606 JJ denotes definitive
T10119 22607-22616 JJ denotes erythroid
T10120 22617-22622 NNS denotes cells
T10121 22623-22629 VBP denotes mature
T10122 22629-22630 , denotes ,
T10123 22631-22639 VBZ denotes suggests
T10124 22640-22644 IN denotes that
T10125 22645-22649 NNP denotes Sox6
T10126 22650-22652 VBZ denotes is
T10127 22653-22655 DT denotes an
T10128 22656-22665 JJ denotes important
T10129 22666-22675 NN denotes regulator
T10130 22676-22678 IN denotes in
T10131 22679-22689 JJ denotes definitive
T10132 22690-22704 NNS denotes erythropoiesis
T10133 22704-22705 . denotes .
T10134 22706-22708 TO denotes To
T10135 22709-22718 VB denotes determine
T10136 22719-22722 DT denotes the
T10137 22723-22731 JJ denotes temporal
T10138 22732-22735 CC denotes and
T10139 22736-22743 JJ denotes spatial
T10140 22744-22754 NN denotes expression
T10141 22755-22762 NN denotes pattern
T10142 22763-22765 IN denotes of
T10143 22766-22770 NNP denotes Sox6
T10144 22770-22771 , denotes ,
T10145 22772-22780 NNP denotes Northern
T10146 22781-22785 NN denotes blot
T10147 22786-22789 CC denotes and
T10148 22790-22792 IN denotes in
T10149 22793-22797 NN denotes situ
T10150 22798-22811 NN denotes hybridization
T10151 22812-22818 NNS denotes assays
T10152 22819-22823 VBD denotes were
T10153 22824-22832 VBN denotes employed
T10154 22832-22833 . denotes .
T10155 22834-22836 IN denotes As
T10156 22837-22842 VBN denotes shown
T10157 22843-22845 IN denotes in
T10158 22846-22852 NN denotes Figure
T10159 22853-22855 CD denotes 6A
T10160 22855-22856 , denotes ,
T10161 22857-22861 NNP denotes Sox6
T10162 22862-22864 VBZ denotes is
T10163 22865-22875 JJ denotes detectable
T10164 22876-22878 IN denotes by
T10165 22879-22887 NNP denotes Northern
T10166 22888-22892 NN denotes blot
T10167 22893-22902 NN denotes beginning
T10168 22903-22905 IN denotes at
T10169 22906-22910 CD denotes 10.5
T10170 22911-22914 NN denotes dpc
T10171 22914-22915 , denotes ,
T10172 22916-22926 JJ denotes coincident
T10173 22927-22931 IN denotes with
T10174 22932-22935 DT denotes the
T10175 22936-22944 JJ denotes temporal
T10176 22945-22950 NN denotes onset
T10177 22951-22953 IN denotes of
T10178 22954-22964 JJ denotes definitive
T10179 22965-22979 NNS denotes erythropoiesis
T10180 22980-22982 IN denotes in
T10181 22983-22986 DT denotes the
T10182 22987-22992 NN denotes liver
T10183 22992-22993 . denotes .
T10184 22994-23005 RB denotes Furthermore
T10185 23005-23006 , denotes ,
T10186 23007-23009 IN denotes in
T10187 23010-23014 NN denotes situ
T10188 23015-23028 NN denotes hybridization
T10189 23029-23034 VBZ denotes shows
T10190 23035-23039 IN denotes that
T10191 23040-23044 NNP denotes Sox6
T10192 23045-23047 VBZ denotes is
T10193 23048-23054 RB denotes highly
T10194 23055-23066 VBN denotes transcribed
T10195 23067-23069 IN denotes in
T10196 23070-23078 JJ denotes 12.5-dpc
T10197 23079-23084 NN denotes liver
T10198 23084-23085 , denotes ,
T10199 23086-23089 CC denotes but
T10200 23090-23093 RB denotes not
T10201 23094-23096 IN denotes in
T10202 23097-23101 NN denotes yolk
T10203 23102-23105 NN denotes sac
T10204 23106-23111 NN denotes blood
T10205 23112-23119 NNS denotes islands
T10206 23120-23122 IN denotes at
T10207 23123-23126 CD denotes 7.5
T10208 23127-23130 NN denotes dpc
T10209 23131-23132 -LRB- denotes (
T10210 23132-23138 NN denotes Figure
T10211 23139-23141 NN denotes 6B
T10212 23141-23142 -RRB- denotes )
T10213 23142-23143 . denotes .
T10214 23144-23153 RB denotes Therefore
T10215 23153-23154 , denotes ,
T10216 23155-23159 JJ denotes Sox6
T10217 23160-23170 NN denotes expression
T10218 23171-23173 VBZ denotes is
T10219 23174-23184 RB denotes temporally
T10220 23185-23188 CC denotes and
T10221 23189-23198 RB denotes spatially
T10222 23199-23209 JJ denotes coincident
T10223 23210-23214 IN denotes with
T10224 23215-23225 JJ denotes definitive
T10225 23225-23226 , denotes ,
T10226 23227-23230 CC denotes but
T10227 23231-23234 RB denotes not
T10228 23235-23244 JJ denotes primitive
T10229 23244-23245 , denotes ,
T10230 23246-23260 NNS denotes erythropoiesis
T10231 23260-23261 . denotes .
T10232 23262-23267 DT denotes These
T10233 23268-23272 NNS denotes data
T10234 23272-23273 , denotes ,
T10235 23274-23279 VBN denotes taken
T10236 23280-23288 RB denotes together
T10237 23289-23293 IN denotes with
T10238 23294-23297 DT denotes the
T10239 23298-23309 NN denotes observation
T10240 23310-23314 IN denotes that
T10241 23315-23317 JJ denotes ɛy
T10242 23318-23324 NN denotes globin
T10243 23325-23327 VBZ denotes is
T10244 23328-23334 RB denotes highly
T10245 23335-23344 VBN denotes expressed
T10246 23345-23347 IN denotes in
T10247 23348-23351 DT denotes the
T10248 23352-23357 NN denotes liver
T10249 23358-23363 NNS denotes cells
T10250 23364-23366 IN denotes of
T10251 23367-23375 JJ denotes 14.5-dpc
T10252 23376-23381 JJ denotes p100H
T10253 23382-23388 JJ denotes mutant
T10254 23389-23393 NNS denotes mice
T10255 23394-23395 -LRB- denotes (
T10256 23395-23401 NN denotes Figure
T10257 23402-23403 CD denotes 5
T10258 23403-23404 -RRB- denotes )
T10259 23404-23405 , denotes ,
T10260 23406-23417 VBP denotes demonstrate
T10261 23418-23422 IN denotes that
T10262 23423-23427 JJ denotes Sox6
T10263 23428-23437 NNS denotes functions
T10264 23438-23440 IN denotes in
T10265 23441-23451 JJ denotes definitive
T10266 23452-23466 NNS denotes erythropoiesis
T10267 23466-23467 . denotes .
T10522 24516-24522 JJ denotes Mutant
T10523 24523-24528 NNP denotes p100H
T10524 24529-24533 NNP denotes Mice
T10525 24534-24538 NNP denotes Have
T10526 24539-24545 JJR denotes Higher
T10527 24546-24553 NNS denotes Numbers
T10528 24554-24556 IN denotes of
T10529 24557-24566 NNP denotes Nucleated
T10530 24567-24570 NNP denotes Red
T10531 24571-24576 NNP denotes Cells
T10532 24577-24582 IN denotes Among
T10533 24583-24586 DT denotes the
T10534 24587-24592 JJ denotes other
T10535 24593-24597 JJ denotes Sox6
T10536 24598-24605 NNS denotes effects
T10537 24606-24608 IN denotes in
T10538 24609-24623 NN denotes erythropoiesis
T10539 24623-24624 , denotes ,
T10540 24625-24627 PRP denotes we
T10541 24628-24632 VBP denotes have
T10542 24633-24640 VBN denotes noticed
T10543 24641-24645 IN denotes that
T10544 24646-24651 EX denotes there
T10545 24652-24655 VBP denotes are
T10546 24656-24660 RBR denotes more
T10547 24661-24670 JJ denotes nucleated
T10548 24671-24674 JJ denotes red
T10549 24675-24680 NN denotes blood
T10550 24681-24686 NNS denotes cells
T10551 24687-24698 VBG denotes circulating
T10552 24699-24701 IN denotes in
T10553 24702-24707 JJ denotes p100H
T10554 24708-24714 JJ denotes mutant
T10555 24715-24719 NNS denotes mice
T10556 24720-24724 IN denotes than
T10557 24725-24727 IN denotes in
T10558 24728-24730 NNP denotes WT
T10559 24731-24735 NNS denotes mice
T10560 24736-24738 IN denotes at
T10561 24739-24743 CD denotes 14.5
T10562 24744-24747 NN denotes dpc
T10563 24748-24751 CC denotes and
T10564 24752-24756 CD denotes 18.5
T10565 24757-24760 NN denotes dpc
T10566 24761-24762 -LRB- denotes (
T10567 24762-24768 NN denotes Figure
T10568 24769-24771 NN denotes 7A
T10569 24771-24772 -RRB- denotes )
T10570 24772-24773 . denotes .
T10571 24774-24781 RB denotes However
T10572 24781-24782 , denotes ,
T10573 24783-24785 IN denotes at
T10574 24786-24795 JJ denotes postnatal
T10575 24796-24799 NN denotes day
T10576 24800-24804 CD denotes 10.5
T10577 24804-24805 , denotes ,
T10578 24806-24808 PRP denotes we
T10579 24809-24811 VBP denotes do
T10580 24812-24815 RB denotes not
T10581 24816-24819 VB denotes see
T10582 24820-24831 VBG denotes circulating
T10583 24832-24841 JJ denotes nucleated
T10584 24842-24845 JJ denotes red
T10585 24846-24851 NNS denotes cells
T10586 24852-24854 IN denotes in
T10587 24855-24861 DT denotes either
T10588 24862-24864 NNP denotes WT
T10589 24865-24867 CC denotes or
T10590 24868-24874 JJ denotes mutant
T10591 24875-24879 NNS denotes mice
T10592 24879-24880 , denotes ,
T10593 24881-24891 VBG denotes suggesting
T10594 24892-24896 IN denotes that
T10595 24897-24901 DT denotes this
T10596 24902-24905 MD denotes may
T10597 24906-24908 VB denotes be
T10598 24909-24910 DT denotes a
T10599 24911-24920 JJ denotes transient
T10600 24921-24927 NN denotes effect
T10601 24927-24928 . denotes .
T10602 24929-24931 IN denotes In
T10603 24932-24940 NN denotes addition
T10604 24940-24941 , denotes ,
T10605 24942-24945 DT denotes the
T10606 24946-24952 JJ denotes mutant
T10607 24953-24958 NN denotes liver
T10608 24959-24964 VBZ denotes shows
T10609 24965-24966 DT denotes a
T10610 24967-24978 JJ denotes significant
T10611 24979-24987 NN denotes increase
T10612 24988-24990 IN denotes in
T10613 24991-25004 JJ denotes hematopoietic
T10614 25005-25014 NN denotes precursor
T10615 25015-25020 NNS denotes cells
T10616 25021-25030 VBG denotes including
T10617 25031-25040 JJ denotes nucleated
T10618 25041-25053 NNS denotes erythrocytes
T10619 25054-25056 IN denotes at
T10620 25057-25061 CD denotes 18.5
T10621 25062-25065 NN denotes dpc
T10622 25066-25067 -LRB- denotes (
T10623 25067-25073 NN denotes Figure
T10624 25074-25076 NN denotes 7B
T10625 25076-25077 -RRB- denotes )
T10626 25077-25078 . denotes .
T10627 25079-25083 DT denotes This
T10628 25084-25094 NN denotes alteration
T10629 25095-25097 VBZ denotes is
T10630 25098-25103 VBN denotes noted
T10631 25104-25106 IN denotes as
T10632 25107-25112 JJ denotes early
T10633 25113-25115 IN denotes as
T10634 25116-25120 CD denotes 14.5
T10635 25121-25124 NN denotes dpc
T10636 25124-25125 . denotes .
T10637 25126-25131 DT denotes These
T10638 25132-25144 NNS denotes observations
T10639 25145-25152 VBP denotes suggest
T10640 25153-25157 IN denotes that
T10641 25158-25165 IN denotes besides
T10642 25166-25175 VBG denotes silencing
T10643 25176-25179 DT denotes the
T10644 25180-25182 JJ denotes ɛy
T10645 25183-25189 NN denotes globin
T10646 25190-25194 NN denotes gene
T10647 25194-25195 , denotes ,
T10648 25196-25200 NNP denotes Sox6
T10649 25201-25204 MD denotes may
T10650 25205-25211 VB denotes affect
T10651 25212-25215 JJ denotes red
T10652 25216-25220 NN denotes cell
T10653 25221-25231 NN denotes maturation
T10654 25231-25232 . denotes .
T13803 25551-25553 IN denotes In
T13804 25554-25558 DT denotes this
T13805 25559-25565 NN denotes report
T13806 25565-25566 , denotes ,
T13807 25567-25569 PRP denotes we
T13808 25570-25574 VBP denotes show
T13809 25575-25579 IN denotes that
T13810 25580-25584 NNP denotes Sox6
T13811 25585-25587 VBZ denotes is
T13812 25588-25589 DT denotes a
T13813 25590-25595 JJ denotes novel
T13814 25596-25602 NN denotes factor
T13815 25603-25605 IN denotes in
T13816 25606-25609 DT denotes the
T13817 25610-25621 JJ denotes complicated
T13818 25622-25632 NN denotes regulation
T13819 25633-25642 NN denotes mechanism
T13820 25643-25645 IN denotes of
T13821 25646-25652 NN denotes globin
T13822 25653-25658 NNS denotes genes
T13823 25658-25659 . denotes .
T13824 25660-25662 IN denotes In
T13825 25663-25666 DT denotes the
T13826 25667-25671 NNP denotes Sox6
T13827 25672-25676 NN denotes null
T13828 25677-25682 NN denotes mouse
T13829 25682-25683 , denotes ,
T13830 25684-25689 EX denotes there
T13831 25690-25692 VBZ denotes is
T13832 25693-25694 DT denotes a
T13833 25695-25704 JJ denotes transient
T13834 25705-25711 NN denotes effect
T13835 25712-25714 IN denotes on
T13836 25715-25718 DT denotes the
T13837 25719-25728 JJ denotes embryonic
T13838 25729-25735 NN denotes globin
T13839 25736-25741 NNS denotes genes
T13840 25741-25742 , denotes ,
T13841 25743-25744 NN denotes ζ
T13842 25745-25748 CC denotes and
T13843 25749-25752 NNP denotes βH1
T13844 25752-25753 , denotes ,
T13845 25754-25757 CC denotes and
T13846 25758-25759 DT denotes a
T13847 25760-25770 JJ denotes persistent
T13848 25771-25783 NN denotes upregulation
T13849 25784-25786 IN denotes of
T13850 25787-25790 DT denotes the
T13851 25791-25793 JJ denotes ɛy
T13852 25794-25800 NN denotes globin
T13853 25801-25805 NN denotes gene
T13854 25805-25806 . denotes .
T13855 25807-25811 JJ denotes Sox6
T13856 25812-25820 RB denotes directly
T13857 25821-25830 VBZ denotes regulates
T13858 25831-25834 CC denotes and
T13859 25835-25840 VBZ denotes binds
T13860 25841-25843 TO denotes to
T13861 25844-25847 DT denotes the
T13862 25848-25856 JJ denotes proximal
T13863 25857-25865 NN denotes promoter
T13864 25866-25868 IN denotes of
T13865 25869-25871 JJ denotes ɛy
T13866 25872-25876 NN denotes gene
T13867 25877-25880 CC denotes and
T13868 25881-25890 VBZ denotes represses
T13869 25891-25894 DT denotes the
T13870 25895-25904 JJ denotes ɛy-globin
T13871 25905-25909 NN denotes gene
T13872 25910-25912 IN denotes in
T13873 25913-25923 JJ denotes definitive
T13874 25924-25938 NNS denotes erythropoiesis
T13875 25938-25939 . denotes .
T13876 25940-25944 JJ denotes Sox6
T13877 25945-25952 VBZ denotes belongs
T13878 25953-25955 TO denotes to
T13879 25956-25961 NN denotes group
T13880 25962-25963 NNP denotes D
T13881 25964-25966 IN denotes of
T13882 25967-25970 DT denotes the
T13883 25971-25974 NNP denotes Sox
T13884 25975-25981 NN denotes family
T13885 25982-25984 IN denotes of
T13886 25985-25993 NNS denotes proteins
T13887 25994-25998 WDT denotes that
T13888 25999-26007 VBZ denotes includes
T13889 26008-26012 NNS denotes Sox5
T13890 26012-26013 , denotes ,
T13891 26014-26016 CD denotes 12
T13892 26016-26017 , denotes ,
T13893 26018-26020 CD denotes 13
T13894 26020-26021 , denotes ,
T13895 26022-26025 CC denotes and
T13896 26026-26028 CD denotes 23
T13897 26029-26030 NNP denotes [
T13898 26030-26032 CD denotes 34
T13899 26032-26033 NNP denotes ]
T13900 26033-26034 . denotes .
T13901 26035-26040 NNP denotes Group
T13902 26041-26042 NNP denotes D
T13903 26043-26046 NNP denotes Sox
T13904 26047-26055 NNS denotes proteins
T13905 26056-26063 VBP denotes contain
T13906 26064-26065 DT denotes a
T13907 26066-26072 VBN denotes coiled
T13908 26073-26079 VBN denotes coiled
T13909 26080-26086 NN denotes domain
T13910 26087-26091 WDT denotes that
T13911 26092-26100 VBZ denotes mediates
T13912 26101-26105 NN denotes homo
T13913 26105-26106 : denotes -
T13914 26107-26110 CC denotes and
T13915 26111-26129 NN denotes heterodimerization
T13916 26130-26131 NNP denotes [
T13917 26131-26135 CD denotes 6,35
T13918 26135-26136 NNP denotes ]
T13919 26136-26137 . denotes .
T13920 26138-26150 RB denotes Functionally
T13921 26150-26151 , denotes ,
T13922 26152-26164 NN denotes dimerization
T13923 26165-26167 IN denotes of
T13924 26168-26172 NNS denotes Sox5
T13925 26173-26176 CC denotes and
T13926 26177-26181 NNP denotes Sox6
T13927 26182-26185 VBZ denotes has
T13928 26186-26190 VBN denotes been
T13929 26191-26196 VBN denotes shown
T13930 26197-26199 TO denotes to
T13931 26200-26207 RB denotes greatly
T13932 26208-26216 VB denotes increase
T13933 26217-26220 DT denotes the
T13934 26221-26228 JJ denotes binding
T13935 26229-26239 NN denotes efficiency
T13936 26240-26242 IN denotes of
T13937 26243-26246 DT denotes the
T13938 26247-26250 CD denotes two
T13939 26251-26254 NNP denotes Sox
T13940 26255-26263 NNS denotes proteins
T13941 26264-26266 TO denotes to
T13942 26267-26270 NNP denotes DNA
T13943 26271-26275 IN denotes that
T13944 26276-26284 VBZ denotes contains
T13945 26285-26293 JJ denotes adjacent
T13946 26294-26297 NNP denotes Sox
T13947 26298-26303 NNS denotes sites
T13948 26304-26305 NNP denotes [
T13949 26305-26306 CD denotes 6
T13950 26306-26307 NNP denotes ]
T13951 26307-26308 . denotes .
T13952 26309-26311 IN denotes In
T13953 26312-26320 NN denotes addition
T13954 26320-26321 , denotes ,
T13955 26322-26326 JJ denotes Sox6
T13956 26327-26332 NNS denotes binds
T13957 26333-26337 RBR denotes more
T13958 26338-26346 RB denotes strongly
T13959 26347-26349 TO denotes to
T13960 26350-26352 DT denotes an
T13961 26353-26360 JJ denotes HMG-box
T13962 26361-26366 NN denotes dimer
T13963 26367-26372 NN denotes motif
T13964 26373-26377 IN denotes than
T13965 26378-26380 TO denotes to
T13966 26381-26382 DT denotes a
T13967 26383-26389 JJ denotes single
T13968 26390-26397 JJ denotes HMG-box
T13969 26398-26403 NN denotes motif
T13970 26404-26405 NN denotes [
T13971 26405-26406 CD denotes 5
T13972 26406-26407 NNP denotes ]
T13973 26407-26408 . denotes .
T13974 26409-26418 RB denotes Therefore
T13975 26418-26419 , denotes ,
T13976 26420-26422 PRP denotes it
T13977 26423-26430 VBZ denotes appears
T13978 26431-26435 IN denotes that
T13979 26436-26442 NN denotes target
T13980 26443-26448 NNS denotes genes
T13981 26449-26452 IN denotes for
T13982 26453-26458 NN denotes group
T13983 26459-26460 NNP denotes D
T13984 26461-26464 NNP denotes Sox
T13985 26465-26473 NNS denotes proteins
T13986 26473-26474 , denotes ,
T13987 26475-26479 JJ denotes such
T13988 26480-26482 IN denotes as
T13989 26483-26487 NNP denotes Sox6
T13990 26487-26488 , denotes ,
T13991 26489-26497 RB denotes probably
T13992 26498-26504 NN denotes harbor
T13993 26505-26510 NNS denotes pairs
T13994 26511-26513 IN denotes of
T13995 26514-26517 NNP denotes HMG
T13996 26518-26525 JJ denotes binding
T13997 26526-26531 NNS denotes sites
T13998 26532-26536 IN denotes with
T13999 26537-26538 DT denotes a
T14000 26539-26552 NN denotes configuration
T14001 26553-26563 JJ denotes compatible
T14002 26564-26568 IN denotes with
T14003 26569-26576 JJ denotes binding
T14004 26577-26579 IN denotes of
T14005 26580-26585 JJ denotes D-Sox
T14006 26586-26593 NN denotes protein
T14007 26594-26600 NNS denotes dimers
T14008 26600-26601 . denotes .
T14009 26602-26608 RB denotes Indeed
T14010 26608-26609 , denotes ,
T14011 26610-26612 IN denotes in
T14012 26613-26616 DT denotes the
T14013 26617-26624 JJ denotes present
T14014 26625-26630 NN denotes study
T14015 26630-26631 , denotes ,
T14016 26632-26635 DT denotes the
T14017 26636-26643 VBN denotes defined
T14018 26644-26648 NNP denotes Sox6
T14019 26649-26655 NN denotes target
T14020 26656-26664 NN denotes sequence
T14021 26665-26667 IN denotes of
T14022 26668-26671 DT denotes the
T14023 26672-26674 JJ denotes ɛy
T14024 26675-26683 NN denotes promoter
T14025 26684-26692 VBZ denotes contains
T14026 26693-26696 CD denotes two
T14027 26697-26705 JJ denotes Sox/Sox6
T14028 26706-26715 NN denotes consensus
T14029 26716-26721 NNS denotes sites
T14030 26722-26723 -LRB- denotes (
T14031 26723-26729 NN denotes Figure
T14032 26730-26732 NN denotes 3A
T14033 26732-26733 -RRB- denotes )
T14034 26733-26734 . denotes .
T14035 26735-26747 RB denotes Functionally
T14036 26747-26748 , denotes ,
T14037 26749-26753 DT denotes both
T14038 26754-26759 NNS denotes sites
T14039 26760-26763 VBP denotes are
T14040 26764-26773 JJ denotes essential
T14041 26774-26777 IN denotes for
T14042 26778-26782 JJ denotes Sox6
T14043 26783-26790 JJ denotes binding
T14044 26791-26793 TO denotes to
T14045 26794-26797 DT denotes the
T14046 26798-26800 JJ denotes ɛy
T14047 26801-26809 NN denotes promoter
T14048 26810-26813 CC denotes and
T14049 26814-26824 NN denotes repression
T14050 26825-26827 IN denotes of
T14051 26828-26831 PRP$ denotes its
T14052 26832-26840 NN denotes activity
T14053 26841-26842 -LRB- denotes (
T14054 26842-26848 NN denotes Figure
T14055 26849-26851 CD denotes 3E
T14056 26852-26855 CC denotes and
T14057 26856-26858 CD denotes 3F
T14058 26858-26859 -RRB- denotes )
T14059 26859-26860 . denotes .
T14060 26861-26866 DT denotes These
T14061 26867-26879 NNS denotes observations
T14062 26880-26887 VBP denotes suggest
T14063 26888-26892 IN denotes that
T14064 26893-26897 JJ denotes Sox6
T14065 26898-26903 NNS denotes binds
T14066 26904-26906 TO denotes to
T14067 26907-26911 DT denotes this
T14068 26912-26920 NN denotes sequence
T14069 26921-26923 IN denotes of
T14070 26924-26927 DT denotes the
T14071 26928-26930 JJ denotes ɛy
T14072 26931-26939 NN denotes promoter
T14073 26940-26946 CC denotes either
T14074 26947-26949 IN denotes as
T14075 26950-26951 DT denotes a
T14076 26952-26961 NN denotes homodimer
T14077 26962-26964 CC denotes or
T14078 26965-26967 IN denotes as
T14079 26968-26969 DT denotes a
T14080 26970-26981 NN denotes heterodimer
T14081 26982-26986 IN denotes with
T14082 26987-26992 JJ denotes other
T14083 26993-26996 NNP denotes Sox
T14084 26997-27005 NNS denotes proteins
T14085 27005-27006 . denotes .
T14086 27007-27014 IN denotes Because
T14087 27015-27018 NNP denotes Sox
T14088 27019-27027 NNS denotes proteins
T14089 27028-27037 VBP denotes recognize
T14090 27038-27039 DT denotes a
T14091 27040-27045 JJ denotes short
T14092 27046-27050 JJ denotes 6-bp
T14093 27051-27063 JJ denotes core-binding
T14094 27064-27072 NN denotes sequence
T14095 27073-27077 WDT denotes that
T14096 27078-27084 VBZ denotes allows
T14097 27085-27088 IN denotes for
T14098 27089-27101 JJ denotes considerable
T14099 27102-27112 NN denotes degeneracy
T14100 27112-27113 , denotes ,
T14101 27114-27117 DT denotes the
T14102 27118-27129 NN denotes specificity
T14103 27130-27132 IN denotes of
T14104 27133-27138 PRP$ denotes their
T14105 27139-27146 NNS denotes actions
T14106 27147-27149 VBZ denotes is
T14107 27150-27157 VBN denotes thought
T14108 27158-27160 TO denotes to
T14109 27161-27165 VB denotes rely
T14110 27166-27170 IN denotes upon
T14111 27171-27183 NNS denotes interactions
T14112 27184-27188 IN denotes with
T14113 27189-27194 JJ denotes other
T14114 27195-27208 NN denotes transcription
T14115 27209-27216 NNS denotes factors
T14116 27217-27218 NNP denotes [
T14117 27218-27220 CD denotes 36
T14118 27220-27221 NNP denotes ]
T14119 27221-27222 . denotes .
T14120 27223-27225 IN denotes In
T14121 27226-27229 PRP$ denotes our
T14122 27230-27235 NNS denotes EMSAs
T14123 27235-27236 , denotes ,
T14124 27237-27239 PRP denotes we
T14125 27240-27243 VBD denotes had
T14126 27244-27246 TO denotes to
T14127 27247-27250 VB denotes run
T14128 27251-27254 DT denotes the
T14129 27255-27270 NN denotes electrophoresis
T14130 27271-27273 IN denotes on
T14131 27274-27275 DT denotes a
T14132 27276-27277 CD denotes 4
T14133 27277-27278 NN denotes %
T14134 27279-27280 CD denotes 6
T14135 27280-27281 NN denotes %
T14136 27282-27285 NN denotes gel
T14137 27286-27289 IN denotes for
T14138 27290-27292 IN denotes at
T14139 27293-27298 JJS denotes least
T14140 27299-27300 CD denotes 4
T14141 27301-27302 CD denotes 8
T14142 27303-27304 NN denotes h
T14143 27305-27307 TO denotes to
T14144 27308-27314 VB denotes detect
T14145 27315-27318 DT denotes the
T14146 27319-27334 JJ denotes Sox6-associated
T14147 27335-27339 NN denotes band
T14148 27339-27340 , denotes ,
T14149 27341-27351 VBG denotes suggesting
T14150 27352-27356 IN denotes that
T14151 27357-27361 NNP denotes Sox6
T14152 27362-27364 VBZ denotes is
T14153 27365-27369 NN denotes part
T14154 27370-27372 IN denotes of
T14155 27373-27374 DT denotes a
T14156 27375-27379 JJ denotes high
T14157 27380-27389 JJ denotes molecular
T14158 27390-27396 NN denotes weight
T14159 27397-27404 NN denotes complex
T14160 27404-27405 . denotes .
T14161 27406-27407 DT denotes A
T14162 27408-27411 JJ denotes few
T14163 27412-27417 JJ denotes other
T14164 27418-27420 JJ denotes ɛy
T14165 27421-27427 NN denotes globin
T14166 27428-27438 NNS denotes repressors
T14167 27439-27443 VBP denotes have
T14168 27444-27448 VBN denotes been
T14169 27449-27457 VBN denotes reported
T14170 27458-27460 TO denotes to
T14171 27461-27465 NN denotes bind
T14172 27466-27468 TO denotes to
T14173 27469-27472 NNP denotes DNA
T14174 27473-27482 NNS denotes sequences
T14175 27483-27487 IN denotes near
T14176 27488-27491 DT denotes the
T14177 27492-27500 NNP denotes Sox/Sox6
T14178 27501-27510 NN denotes consensus
T14179 27511-27516 NNS denotes sites
T14180 27516-27517 , denotes ,
T14181 27518-27527 VBG denotes including
T14182 27528-27531 DT denotes the
T14183 27532-27536 NNP denotes DRED
T14184 27537-27544 JJ denotes complex
T14185 27545-27546 NNP denotes [
T14186 27546-27548 CD denotes 37
T14187 27548-27549 NNP denotes ]
T14188 27550-27553 CC denotes and
T14189 27554-27561 NNP denotes COUP-TF
T14190 27562-27563 NNP denotes [
T14191 27563-27565 CD denotes 38
T14192 27565-27566 NNP denotes ]
T14193 27566-27567 . denotes .
T14194 27568-27572 NNS denotes Sox6
T14195 27573-27578 MD denotes might
T14196 27579-27587 VB denotes interact
T14197 27588-27592 IN denotes with
T14198 27593-27598 DT denotes these
T14199 27599-27606 NNS denotes factors
T14200 27607-27610 CC denotes and
T14201 27611-27615 VB denotes form
T14202 27616-27617 DT denotes a
T14203 27618-27623 JJ denotes large
T14204 27624-27634 NN denotes repression
T14205 27635-27642 NN denotes complex
T14206 27642-27643 . denotes .
T14207 27644-27658 NN denotes Identification
T14208 27659-27661 IN denotes of
T14209 27662-27667 JJ denotes other
T14210 27668-27678 NNS denotes components
T14211 27679-27681 IN denotes of
T14212 27682-27685 DT denotes the
T14213 27686-27701 JJ denotes Sox6-containing
T14214 27702-27709 JJ denotes complex
T14215 27710-27720 VBN denotes associated
T14216 27721-27725 IN denotes with
T14217 27726-27729 DT denotes the
T14218 27730-27732 JJ denotes ɛy
T14219 27733-27741 NN denotes promoter
T14220 27742-27746 MD denotes will
T14221 27747-27751 VB denotes shed
T14222 27752-27757 NN denotes light
T14223 27758-27760 IN denotes on
T14224 27761-27764 PRP$ denotes its
T14225 27765-27774 NN denotes mechanism
T14226 27775-27777 IN denotes of
T14227 27778-27788 NN denotes repression
T14228 27788-27789 . denotes .
T14229 27790-27793 NNP denotes Sox
T14230 27794-27802 NNS denotes proteins
T14231 27803-27807 NN denotes bind
T14232 27808-27811 CC denotes and
T14233 27812-27816 VB denotes bend
T14234 27817-27823 JJ denotes linear
T14235 27824-27827 NN denotes DNA
T14236 27828-27830 IN denotes by
T14237 27831-27838 JJ denotes partial
T14238 27839-27852 NN denotes intercalation
T14239 27853-27855 IN denotes in
T14240 27856-27859 DT denotes the
T14241 27860-27865 JJ denotes minor
T14242 27866-27872 NN denotes groove
T14243 27872-27873 , denotes ,
T14244 27874-27877 CC denotes and
T14245 27878-27881 MD denotes can
T14246 27882-27886 RB denotes also
T14247 27887-27891 NN denotes bind
T14248 27892-27894 TO denotes to
T14249 27895-27903 JJ denotes four-way
T14250 27904-27913 NNS denotes junctions
T14251 27914-27915 VBP denotes [
T14252 27915-27916 CD denotes 2
T14253 27917-27918 CD denotes 4
T14254 27918-27919 NNP denotes ]
T14255 27919-27920 . denotes .
T14256 27921-27930 RB denotes Therefore
T14257 27930-27931 , denotes ,
T14258 27932-27935 CD denotes one
T14259 27936-27946 JJ denotes attractive
T14260 27947-27952 NN denotes model
T14261 27953-27955 TO denotes to
T14262 27956-27963 VB denotes explain
T14263 27964-27967 WRB denotes how
T14264 27968-27972 JJ denotes Sox6
T14265 27973-27981 NNS denotes proteins
T14266 27982-27989 VBP denotes control
T14267 27990-27994 NN denotes gene
T14268 27995-28005 NN denotes expression
T14269 28006-28008 VBZ denotes is
T14270 28009-28013 IN denotes that
T14271 28014-28018 PRP denotes they
T14272 28019-28027 VBP denotes function
T14273 28028-28030 IN denotes as
T14274 28031-28044 JJ denotes architectural
T14275 28045-28052 NNS denotes factors
T14276 28053-28058 VBN denotes bound
T14277 28059-28061 TO denotes to
T14278 28062-28065 NNP denotes DNA
T14279 28065-28066 , denotes ,
T14280 28067-28078 VBG denotes influencing
T14281 28079-28084 JJ denotes local
T14282 28085-28094 NN denotes chromatin
T14283 28095-28104 NN denotes structure
T14284 28105-28107 IN denotes by
T14285 28108-28115 VBG denotes bending
T14286 28116-28119 NNP denotes DNA
T14287 28120-28123 CC denotes and
T14288 28124-28126 IN denotes by
T14289 28127-28137 VBG denotes assembling
T14290 28138-28150 JJ denotes multiprotein
T14291 28151-28166 JJ denotes transcriptional
T14292 28167-28176 NNS denotes complexes
T14293 28176-28177 . denotes .
T14294 28178-28180 IN denotes By
T14295 28181-28189 VBG denotes changing
T14296 28190-28193 DT denotes the
T14297 28194-28199 JJ denotes local
T14298 28200-28209 NN denotes chromatin
T14299 28210-28219 NN denotes structure
T14300 28219-28220 , denotes ,
T14301 28221-28225 NNP denotes Sox6
T14302 28226-28231 MD denotes could
T14303 28232-28238 RB denotes either
T14304 28239-28248 VB denotes interfere
T14305 28249-28253 IN denotes with
T14306 28254-28261 JJ denotes binding
T14307 28262-28264 IN denotes of
T14308 28265-28270 JJ denotes other
T14309 28271-28281 NNS denotes activators
T14310 28282-28284 TO denotes to
T14311 28285-28288 DT denotes the
T14312 28289-28297 NN denotes promoter
T14313 28298-28300 CC denotes or
T14314 28301-28311 VB denotes facilitate
T14315 28312-28319 JJ denotes binding
T14316 28320-28322 IN denotes of
T14317 28323-28328 JJ denotes other
T14318 28329-28339 NNS denotes repressors
T14319 28339-28340 . denotes .
T14320 28341-28348 DT denotes Another
T14321 28349-28356 NN denotes example
T14322 28357-28359 IN denotes of
T14323 28360-28361 DT denotes a
T14324 28362-28371 NN denotes repressor
T14325 28372-28376 WDT denotes that
T14326 28377-28387 VBZ denotes interferes
T14327 28388-28392 IN denotes with
T14328 28393-28395 DT denotes an
T14329 28396-28405 NN denotes activator
T14330 28406-28408 IN denotes on
T14331 28409-28412 DT denotes the
T14332 28413-28415 JJ denotes ɛy
T14333 28416-28424 NN denotes promoter
T14334 28425-28427 VBZ denotes is
T14335 28428-28432 NNP denotes DRED
T14336 28432-28433 . denotes .
T14337 28434-28438 NNP denotes DRED
T14338 28439-28449 VBZ denotes interferes
T14339 28450-28454 IN denotes with
T14340 28455-28459 NNP denotes EKLF
T14341 28459-28460 , denotes ,
T14342 28461-28463 DT denotes an
T14343 28464-28473 NN denotes activator
T14344 28473-28474 , denotes ,
T14345 28475-28477 IN denotes in
T14346 28478-28485 JJ denotes binding
T14347 28486-28488 TO denotes to
T14348 28489-28492 DT denotes the
T14349 28493-28495 JJ denotes ɛy
T14350 28496-28504 NN denotes promoter
T14351 28505-28506 NNP denotes [
T14352 28506-28508 CD denotes 39
T14353 28508-28509 NNP denotes ]
T14354 28509-28510 . denotes .
T14355 28511-28514 CD denotes Two
T14356 28515-28518 NNP denotes HMG
T14357 28519-28532 JJ denotes architectural
T14358 28533-28541 NNS denotes proteins
T14359 28542-28543 -LRB- denotes (
T14360 28543-28552 RB denotes distantly
T14361 28553-28560 VBN denotes related
T14362 28561-28563 TO denotes to
T14363 28564-28567 DT denotes the
T14364 28568-28571 NNP denotes Sox
T14365 28572-28578 NN denotes family
T14366 28579-28581 IN denotes of
T14367 28582-28595 NN denotes transcription
T14368 28596-28603 NNS denotes factors
T14369 28603-28604 -RRB- denotes )
T14370 28604-28605 , denotes ,
T14371 28606-28611 NNP denotes HMG-I
T14372 28612-28615 CC denotes and
T14373 28616-28621 NNP denotes HMG-Y
T14374 28621-28622 , denotes ,
T14375 28623-28627 VBD denotes were
T14376 28628-28640 VBN denotes demonstrated
T14377 28641-28643 TO denotes to
T14378 28644-28648 NN denotes bind
T14379 28649-28651 TO denotes to
T14380 28652-28655 DT denotes the
T14381 28656-28661 JJ denotes human
T14382 28662-28667 NN denotes adult
T14383 28668-28669 NN denotes β
T14384 28670-28676 NN denotes globin
T14385 28677-28686 NNS denotes silencers
T14386 28687-28688 -LRB- denotes (
T14387 28688-28697 NNS denotes silencers
T14388 28698-28699 PRP denotes I
T14389 28700-28703 CC denotes and
T14390 28704-28706 NNP denotes II
T14391 28706-28707 -RRB- denotes )
T14392 28708-28711 CC denotes and
T14393 28712-28717 VB denotes cause
T14394 28718-28725 VBG denotes bending
T14395 28726-28728 IN denotes of
T14396 28729-28732 DT denotes the
T14397 28733-28736 NNP denotes DNA
T14398 28736-28737 , denotes ,
T14399 28738-28750 VBG denotes facilitating
T14400 28751-28754 DT denotes the
T14401 28755-28762 JJ denotes binding
T14402 28763-28765 IN denotes of
T14403 28766-28771 JJ denotes other
T14404 28772-28782 NNS denotes repressors
T14405 28783-28784 NNP denotes [
T14406 28784-28786 CD denotes 40
T14407 28786-28787 NNP denotes ]
T14408 28787-28788 . denotes .
T14409 28789-28793 JJ denotes Sox6
T14410 28794-28804 NN denotes expression
T14411 28805-28807 VBZ denotes is
T14412 28808-28818 RB denotes temporally
T14413 28819-28822 CC denotes and
T14414 28823-28832 RB denotes spatially
T14415 28833-28843 JJ denotes coincident
T14416 28844-28848 IN denotes with
T14417 28849-28859 JJ denotes definitive
T14418 28860-28861 -LRB- denotes (
T14419 28861-28864 CC denotes but
T14420 28865-28868 RB denotes not
T14421 28869-28878 JJ denotes primitive
T14422 28878-28879 -RRB- denotes )
T14423 28880-28894 VBZ denotes erythropoiesis
T14424 28895-28896 -LRB- denotes (
T14425 28896-28902 NN denotes Figure
T14426 28903-28904 CD denotes 6
T14427 28904-28905 -RRB- denotes )
T14428 28905-28906 , denotes ,
T14429 28907-28910 CC denotes and
T14430 28911-28915 NNP denotes Sox6
T14431 28916-28925 VBZ denotes represses
T14432 28926-28928 JJ denotes ɛy
T14433 28929-28935 NN denotes globin
T14434 28936-28946 NN denotes expression
T14435 28947-28951 DT denotes both
T14436 28952-28954 IN denotes in
T14437 28955-28959 NN denotes vivo
T14438 28960-28961 -LRB- denotes (
T14439 28961-28967 NN denotes Figure
T14440 28968-28969 CD denotes 1
T14441 28969-28970 -RRB- denotes )
T14442 28971-28974 CC denotes and
T14443 28975-28977 IN denotes in
T14444 28978-28983 NN denotes vitro
T14445 28984-28985 -LRB- denotes (
T14446 28985-28991 NN denotes Figure
T14447 28992-28993 CD denotes 2
T14448 28993-28994 -RRB- denotes )
T14449 28994-28995 . denotes .
T14450 28996-29004 RB denotes Moreover
T14451 29004-29005 , denotes ,
T14452 29006-29008 IN denotes in
T14453 29009-29013 NN denotes situ
T14454 29014-29027 NN denotes hybridization
T14455 29028-29035 RB denotes clearly
T14456 29036-29041 VBZ denotes shows
T14457 29042-29046 IN denotes that
T14458 29047-29050 DT denotes the
T14459 29051-29061 JJ denotes persistent
T14460 29062-29072 NN denotes expression
T14461 29073-29075 IN denotes of
T14462 29076-29078 JJ denotes ɛy
T14463 29079-29085 NN denotes globin
T14464 29086-29088 IN denotes in
T14465 29089-29094 JJ denotes p100H
T14466 29095-29101 JJ denotes mutant
T14467 29102-29106 NNS denotes mice
T14468 29107-29109 VBZ denotes is
T14469 29110-29113 JJ denotes due
T14470 29114-29116 TO denotes to
T14471 29117-29124 NNS denotes defects
T14472 29125-29127 IN denotes in
T14473 29128-29131 DT denotes the
T14474 29132-29141 VBG denotes silencing
T14475 29142-29151 NN denotes mechanism
T14476 29152-29154 IN denotes of
T14477 29155-29165 JJ denotes definitive
T14478 29166-29180 NNS denotes erythropoiesis
T14479 29181-29185 WDT denotes that
T14480 29186-29191 VBZ denotes takes
T14481 29192-29197 NN denotes place
T14482 29198-29200 IN denotes in
T14483 29201-29204 DT denotes the
T14484 29205-29210 NN denotes liver
T14485 29211-29212 -LRB- denotes (
T14486 29212-29218 NN denotes Figure
T14487 29219-29220 CD denotes 5
T14488 29220-29221 -RRB- denotes )
T14489 29221-29222 . denotes .
T14490 29223-29228 VBN denotes Taken
T14491 29229-29237 RB denotes together
T14492 29237-29238 , denotes ,
T14493 29239-29244 DT denotes these
T14494 29245-29249 NNS denotes data
T14495 29250-29261 VBP denotes demonstrate
T14496 29262-29266 IN denotes that
T14497 29267-29271 JJ denotes Sox6
T14498 29272-29281 NNS denotes functions
T14499 29282-29284 IN denotes in
T14500 29285-29295 JJ denotes definitive
T14501 29296-29310 NNS denotes erythropoiesis
T14502 29311-29313 TO denotes to
T14503 29314-29321 NN denotes silence
T14504 29322-29324 NN denotes ɛy
T14505 29325-29331 NN denotes globin
T14506 29332-29342 NN denotes expression
T14507 29342-29343 . denotes .
T14508 29344-29347 DT denotes The
T14509 29348-29358 NN denotes expression
T14510 29359-29364 NN denotes level
T14511 29365-29367 IN denotes of
T14512 29368-29370 JJ denotes ɛy
T14513 29371-29377 NN denotes globin
T14514 29378-29380 IN denotes in
T14515 29381-29391 JJ denotes homozygous
T14516 29392-29396 JJ denotes Sox6
T14517 29397-29401 NN denotes null
T14518 29402-29406 NNS denotes mice
T14519 29407-29409 IN denotes at
T14520 29410-29414 CD denotes 15.5
T14521 29415-29418 NN denotes dpc
T14522 29419-29422 CC denotes and
T14523 29423-29427 CD denotes 18.5
T14524 29428-29431 NN denotes dpc
T14525 29432-29434 VBZ denotes is
T14526 29435-29448 RB denotes statistically
T14527 29449-29459 JJ denotes equivalent
T14528 29460-29462 TO denotes to
T14529 29463-29466 DT denotes the
T14530 29467-29472 NN denotes level
T14531 29473-29475 IN denotes of
T14532 29476-29480 NN denotes βmaj
T14533 29480-29481 NN denotes /
T14534 29481-29484 NN denotes min
T14535 29485-29495 NN denotes expression
T14536 29496-29498 IN denotes in
T14537 29499-29502 DT denotes the
T14538 29503-29509 NNS denotes livers
T14539 29510-29512 IN denotes of
T14540 29513-29521 JJ denotes 15.5-dpc
T14541 29522-29525 CC denotes and
T14542 29526-29534 JJ denotes 18.5-dpc
T14543 29535-29545 JJ denotes homozygous
T14544 29546-29548 NNP denotes WT
T14545 29549-29553 NNS denotes mice
T14546 29554-29555 -LRB- denotes (
T14547 29555-29561 NN denotes Figure
T14548 29562-29563 CD denotes 1
T14549 29563-29564 -RRB- denotes )
T14550 29564-29565 . denotes .
T14551 29566-29570 DT denotes This
T14552 29571-29583 VBZ denotes demonstrates
T14553 29584-29588 IN denotes that
T14554 29589-29596 JJ denotes ectopic
T14555 29597-29607 NN denotes expression
T14556 29608-29610 IN denotes of
T14557 29611-29614 DT denotes the
T14558 29615-29617 JJ denotes ɛy
T14559 29618-29624 NN denotes globin
T14560 29625-29629 NN denotes gene
T14561 29630-29632 VBZ denotes is
T14562 29633-29638 RB denotes quite
T14563 29639-29645 JJ denotes robust
T14564 29646-29648 IN denotes in
T14565 29649-29659 JJ denotes homozygous
T14566 29660-29666 JJ denotes mutant
T14567 29667-29671 NNS denotes mice
T14568 29671-29672 . denotes .
T14569 29673-29676 DT denotes The
T14570 29677-29687 NN denotes expression
T14571 29688-29694 NNS denotes levels
T14572 29695-29697 IN denotes of
T14573 29698-29701 CD denotes two
T14574 29702-29707 JJ denotes other
T14575 29708-29717 JJ denotes embryonic
T14576 29718-29724 NN denotes globin
T14577 29725-29730 NNS denotes genes
T14578 29731-29732 -LRB- denotes (
T14579 29732-29733 NN denotes ζ
T14580 29734-29737 CC denotes and
T14581 29738-29741 CD denotes βh1
T14582 29741-29742 -RRB- denotes )
T14583 29743-29746 VBP denotes are
T14584 29747-29751 RB denotes also
T14585 29752-29758 JJR denotes higher
T14586 29759-29761 IN denotes in
T14587 29762-29767 JJ denotes p100H
T14588 29768-29779 NNS denotes homozygotes
T14589 29779-29780 , denotes ,
T14590 29781-29789 VBN denotes compared
T14591 29790-29794 IN denotes with
T14592 29795-29797 NNP denotes WT
T14593 29797-29798 . denotes .
T14594 29799-29803 IN denotes Like
T14595 29804-29806 VB denotes ɛy
T14596 29806-29807 , denotes ,
T14597 29808-29814 NNS denotes levels
T14598 29815-29817 IN denotes of
T14599 29818-29819 NN denotes ζ
T14600 29820-29823 CC denotes and
T14601 29824-29827 CD denotes βh1
T14602 29828-29831 VBP denotes are
T14603 29832-29844 RB denotes dramatically
T14604 29845-29851 JJR denotes higher
T14605 29852-29854 IN denotes in
T14606 29855-29861 JJ denotes mutant
T14607 29862-29866 NNS denotes mice
T14608 29867-29869 IN denotes at
T14609 29870-29874 CD denotes 15.5
T14610 29875-29878 NN denotes dpc
T14611 29878-29879 . denotes .
T14612 29880-29887 RB denotes However
T14613 29887-29888 , denotes ,
T14614 29889-29895 IN denotes unlike
T14615 29896-29898 JJ denotes ɛy
T14616 29899-29905 NN denotes globin
T14617 29905-29906 , denotes ,
T14618 29907-29908 NN denotes ζ
T14619 29909-29912 CC denotes and
T14620 29913-29916 JJ denotes βh1
T14621 29917-29924 NN denotes decline
T14622 29925-29927 IN denotes in
T14623 29928-29938 NN denotes expression
T14624 29939-29941 IN denotes by
T14625 29942-29945 NN denotes day
T14626 29946-29950 CD denotes 18.5
T14627 29951-29954 NN denotes dpc
T14628 29955-29956 -LRB- denotes (
T14629 29956-29962 NN denotes Figure
T14630 29963-29964 CD denotes 1
T14631 29964-29965 -RRB- denotes )
T14632 29965-29966 , denotes ,
T14633 29967-29977 VBG denotes suggesting
T14634 29978-29982 IN denotes that
T14635 29983-29985 NN denotes ɛy
T14636 29986-29988 VBZ denotes is
T14637 29989-29998 VBN denotes regulated
T14638 29999-30010 RB denotes differently
T14639 30011-30015 IN denotes than
T14640 30016-30017 VB denotes ζ
T14641 30018-30021 CC denotes and
T14642 30022-30025 VB denotes βh1
T14643 30025-30026 . denotes .
T14644 30027-30029 PRP denotes It
T14645 30030-30032 VBZ denotes is
T14646 30033-30041 JJ denotes possible
T14647 30042-30046 IN denotes that
T14648 30047-30051 NNP denotes Sox6
T14649 30052-30055 VBZ denotes has
T14650 30056-30057 DT denotes a
T14651 30058-30065 JJ denotes general
T14652 30066-30072 NN denotes effect
T14653 30073-30075 IN denotes on
T14654 30076-30085 JJ denotes embryonic
T14655 30086-30092 NN denotes globin
T14656 30093-30098 NNS denotes genes
T14657 30099-30100 -LRB- denotes (
T14658 30100-30103 CC denotes and
T14659 30104-30115 JJ denotes erythrocyte
T14660 30116-30126 NN denotes maturation
T14661 30126-30127 -RRB- denotes )
T14662 30128-30130 IN denotes in
T14663 30131-30139 NN denotes addition
T14664 30140-30142 TO denotes to
T14665 30143-30144 DT denotes a
T14666 30145-30153 JJ denotes specific
T14667 30154-30158 NN denotes role
T14668 30159-30161 IN denotes in
T14669 30162-30171 VBG denotes silencing
T14670 30172-30174 NN denotes ɛy
T14671 30174-30175 . denotes .
T14672 30176-30184 IN denotes Although
T14673 30185-30189 JJS denotes most
T14674 30190-30195 JJ denotes p100H
T14675 30196-30202 JJ denotes mutant
T14676 30203-30207 NNS denotes mice
T14677 30208-30211 VBP denotes die
T14678 30212-30216 RB denotes just
T14679 30217-30222 IN denotes after
T14680 30223-30228 VBG denotes being
T14681 30229-30233 VBN denotes born
T14682 30233-30234 , denotes ,
T14683 30235-30236 DT denotes a
T14684 30237-30241 JJ denotes rare
T14685 30242-30245 JJ denotes few
T14686 30246-30253 VBP denotes survive
T14687 30254-30260 RBR denotes longer
T14688 30260-30261 . denotes .
T14689 30262-30266 NN denotes None
T14690 30267-30271 VBP denotes have
T14691 30272-30276 VBN denotes been
T14692 30277-30285 VBN denotes observed
T14693 30286-30288 TO denotes to
T14694 30289-30293 VB denotes live
T14695 30294-30300 JJR denotes longer
T14696 30301-30305 IN denotes than
T14697 30306-30307 CD denotes 2
T14698 30308-30310 NN denotes wk
T14699 30311-30316 IN denotes after
T14700 30317-30322 NN denotes birth
T14701 30323-30324 NNP denotes [
T14702 30324-30326 CD denotes 14
T14703 30326-30327 NNP denotes ]
T14704 30327-30328 . denotes .
T14705 30329-30331 PRP denotes We
T14706 30332-30340 VBD denotes examined
T14707 30341-30342 DT denotes a
T14708 30343-30349 JJ denotes single
T14709 30350-30358 JJ denotes archived
T14710 30359-30365 NN denotes sample
T14711 30366-30368 IN denotes of
T14712 30369-30374 NN denotes liver
T14713 30375-30378 NNP denotes RNA
T14714 30379-30383 IN denotes from
T14715 30384-30385 DT denotes a
T14716 30386-30392 JJ denotes mutant
T14717 30393-30398 NN denotes mouse
T14718 30399-30401 IN denotes on
T14719 30402-30411 JJ denotes postnatal
T14720 30412-30415 NN denotes day
T14721 30416-30420 CD denotes 13.5
T14722 30421-30424 IN denotes for
T14723 30425-30431 NN denotes globin
T14724 30432-30436 NN denotes gene
T14725 30437-30447 NN denotes expression
T14726 30448-30451 CC denotes and
T14727 30452-30460 VBD denotes detected
T14728 30461-30465 JJ denotes high
T14729 30466-30472 NNS denotes levels
T14730 30473-30475 IN denotes of
T14731 30476-30478 JJ denotes ɛy
T14732 30479-30485 NN denotes globin
T14733 30486-30488 IN denotes in
T14734 30489-30493 DT denotes this
T14735 30494-30497 NNP denotes RNA
T14736 30498-30504 NN denotes sample
T14737 30504-30505 , denotes ,
T14738 30506-30514 VBN denotes compared
T14739 30515-30519 IN denotes with
T14740 30520-30532 JJ denotes undetectable
T14741 30533-30535 NN denotes ɛy
T14742 30536-30539 NNP denotes RNA
T14743 30540-30542 IN denotes in
T14744 30543-30545 NNP denotes WT
T14745 30546-30553 NN denotes control
T14746 30554-30558 NNS denotes mice
T14747 30558-30559 . denotes .
T14748 30560-30562 IN denotes At
T14749 30563-30567 DT denotes this
T14750 30568-30573 NN denotes point
T14751 30574-30576 IN denotes in
T14752 30577-30588 NN denotes development
T14753 30588-30589 , denotes ,
T14754 30590-30593 DT denotes the
T14755 30594-30600 NNS denotes levels
T14756 30601-30603 IN denotes of
T14757 30604-30605 NN denotes ζ
T14758 30606-30609 CC denotes and
T14759 30610-30613 CD denotes βh1
T14760 30614-30617 NNP denotes RNA
T14761 30618-30622 VBD denotes were
T14762 30623-30635 JJ denotes undetectable
T14763 30636-30640 DT denotes both
T14764 30641-30643 IN denotes in
T14765 30644-30650 JJ denotes mutant
T14766 30651-30654 CC denotes and
T14767 30655-30657 NNP denotes WT
T14768 30657-30658 : denotes ;
T14769 30659-30666 RB denotes however
T14770 30666-30667 , denotes ,
T14771 30668-30673 NN denotes adult
T14772 30674-30680 JJ denotes β-like
T14773 30681-30687 NN denotes globin
T14774 30688-30691 NNP denotes RNA
T14775 30692-30698 NNS denotes levels
T14776 30699-30703 VBD denotes were
T14777 30704-30714 RB denotes moderately
T14778 30715-30723 VBN denotes elevated
T14779 30724-30726 IN denotes in
T14780 30727-30730 DT denotes the
T14781 30731-30737 JJ denotes mutant
T14782 30738-30741 NNP denotes RNA
T14783 30742-30750 VBN denotes compared
T14784 30751-30755 IN denotes with
T14785 30756-30758 NNP denotes WT
T14786 30759-30760 -LRB- denotes (
T14787 30760-30771 JJ denotes unpublished
T14788 30772-30776 NNS denotes data
T14789 30776-30777 -RRB- denotes )
T14790 30777-30778 , denotes ,
T14791 30779-30786 JJ denotes similar
T14792 30787-30789 TO denotes to
T14793 30790-30794 WP denotes what
T14794 30795-30797 PRP denotes we
T14795 30798-30805 VBP denotes observe
T14796 30806-30808 IN denotes at
T14797 30809-30813 CD denotes 18.5
T14798 30814-30817 NN denotes dpc
T14799 30818-30819 -LRB- denotes (
T14800 30819-30825 NN denotes Figure
T14801 30826-30827 CD denotes 1
T14802 30827-30828 -RRB- denotes )
T14803 30828-30829 . denotes .
T14804 30830-30835 DT denotes These
T14805 30836-30844 NNS denotes findings
T14806 30845-30852 VBP denotes suggest
T14807 30853-30857 IN denotes that
T14808 30858-30862 JJ denotes Sox6
T14809 30863-30872 VBZ denotes continues
T14810 30873-30875 TO denotes to
T14811 30876-30884 VB denotes function
T14812 30885-30896 RB denotes postnatally
T14813 30897-30899 TO denotes to
T14814 30900-30907 NN denotes silence
T14815 30908-30910 NN denotes ɛy
T14816 30911-30917 NN denotes globin
T14817 30918-30928 NN denotes expression
T14818 30929-30932 CC denotes and
T14819 30933-30936 VBZ denotes has
T14820 30937-30938 DT denotes a
T14821 30939-30945 JJ denotes unique
T14822 30946-30954 NN denotes function
T14823 30955-30957 IN denotes in
T14824 30958-30961 DT denotes the
T14825 30962-30972 NN denotes regulation
T14826 30973-30975 IN denotes of
T14827 30976-30985 NN denotes ɛy-globin
T14828 30985-30986 . denotes .
T14829 30987-30990 DT denotes The
T14830 30991-31000 NN denotes mechanism
T14831 31001-31003 IN denotes by
T14832 31004-31009 WDT denotes which
T14833 31010-31014 NNP denotes Sox6
T14834 31015-31024 VBZ denotes regulates
T14835 31025-31028 DT denotes the
T14836 31029-31034 JJ denotes other
T14837 31035-31044 JJ denotes embryonic
T14838 31045-31051 NN denotes globin
T14839 31052-31057 NNS denotes genes
T14840 31058-31065 VBZ denotes remains
T14841 31066-31068 TO denotes to
T14842 31069-31071 VB denotes be
T14843 31072-31082 VBN denotes elucidated
T14844 31082-31083 . denotes .
T14845 31084-31088 NNP denotes Sox6
T14846 31089-31092 VBZ denotes has
T14847 31093-31098 JJ denotes other
T14848 31099-31106 NNS denotes effects
T14849 31107-31109 IN denotes in
T14850 31110-31124 NN denotes erythropoiesis
T14851 31124-31125 , denotes ,
T14852 31126-31135 VBG denotes including
T14853 31136-31137 DT denotes a
T14854 31138-31143 NN denotes delay
T14855 31144-31146 IN denotes in
T14856 31147-31169 NN denotes enucleation/maturation
T14857 31170-31172 IN denotes in
T14858 31173-31178 JJ denotes p100H
T14859 31179-31185 JJ denotes mutant
T14860 31186-31190 NNS denotes mice
T14861 31190-31191 . denotes .
T14862 31192-31196 DT denotes This
T14863 31197-31200 MD denotes may
T14864 31201-31203 VB denotes be
T14865 31204-31207 DT denotes the
T14866 31208-31214 NN denotes result
T14867 31215-31217 IN denotes of
T14868 31218-31226 JJ denotes indirect
T14869 31227-31234 NNS denotes effects
T14870 31234-31235 , denotes ,
T14871 31236-31240 JJ denotes such
T14872 31241-31243 IN denotes as
T14873 31244-31258 JJ denotes stress-induced
T14874 31259-31272 NN denotes proliferation
T14875 31273-31274 -LRB- denotes (
T14876 31274-31283 VBG denotes resulting
T14877 31284-31288 IN denotes from
T14878 31289-31296 JJ denotes cardiac
T14879 31297-31304 NNS denotes defects
T14880 31304-31305 -RRB- denotes )
T14881 31306-31312 CC denotes and/or
T14882 31313-31319 NN denotes anemia
T14883 31319-31320 . denotes .
T14884 31321-31327 JJ denotes Severe
T14885 31328-31334 NN denotes anemia
T14886 31335-31338 MD denotes can
T14887 31339-31343 VB denotes lead
T14888 31344-31346 TO denotes to
T14889 31347-31352 JJ denotes rapid
T14890 31353-31362 JJ denotes premature
T14891 31363-31370 NN denotes release
T14892 31371-31373 IN denotes of
T14893 31374-31377 JJ denotes red
T14894 31378-31383 NNS denotes cells
T14895 31383-31384 , denotes ,
T14896 31385-31390 RB denotes prior
T14897 31391-31393 TO denotes to
T14898 31394-31399 PRP$ denotes their
T14899 31400-31408 JJ denotes complete
T14900 31409-31419 NN denotes maturation
T14901 31419-31420 . denotes .
T14902 31421-31428 RB denotes However
T14903 31428-31429 , denotes ,
T14904 31430-31433 DT denotes the
T14905 31434-31444 NN denotes hematocrit
T14906 31445-31447 IN denotes of
T14907 31448-31456 JJ denotes 18.5-dpc
T14908 31457-31463 JJ denotes mutant
T14909 31464-31468 NNS denotes mice
T14910 31469-31471 VBZ denotes is
T14911 31472-31476 RB denotes only
T14912 31477-31479 CD denotes 20
T14913 31479-31480 NN denotes %
T14914 31481-31486 JJR denotes lower
T14915 31487-31491 IN denotes than
T14916 31492-31496 DT denotes that
T14917 31497-31499 IN denotes of
T14918 31500-31502 NNP denotes WT
T14919 31503-31504 -LRB- denotes (
T14920 31504-31515 JJ denotes unpublished
T14921 31516-31520 NNS denotes data
T14922 31520-31521 -RRB- denotes )
T14923 31521-31522 , denotes ,
T14924 31523-31526 CC denotes and
T14925 31527-31531 DT denotes this
T14926 31532-31536 JJ denotes mild
T14927 31537-31543 NN denotes anemia
T14928 31544-31546 VBZ denotes is
T14929 31547-31555 RB denotes probably
T14930 31556-31559 RB denotes not
T14931 31560-31570 JJ denotes sufficient
T14932 31571-31573 TO denotes to
T14933 31574-31581 VB denotes explain
T14934 31582-31585 DT denotes the
T14935 31586-31592 NN denotes extent
T14936 31593-31595 IN denotes of
T14937 31596-31605 JJ denotes nucleated
T14938 31606-31609 JJ denotes red
T14939 31610-31615 NNS denotes cells
T14940 31615-31616 . denotes .
T14941 31617-31630 RB denotes Alternatively
T14942 31630-31631 , denotes ,
T14943 31632-31636 JJ denotes Sox6
T14944 31637-31643 PRP denotes itself
T14945 31644-31647 MD denotes may
T14946 31648-31652 VB denotes play
T14947 31653-31654 DT denotes a
T14948 31655-31659 NN denotes role
T14949 31660-31662 IN denotes in
T14950 31663-31666 JJ denotes red
T14951 31667-31671 NN denotes cell
T14952 31672-31680 NN denotes terminal
T14953 31681-31696 NN denotes differentiation
T14954 31696-31697 , denotes ,
T14955 31698-31700 IN denotes as
T14956 31701-31703 PRP denotes it
T14957 31704-31707 VBZ denotes has
T14958 31708-31712 VBN denotes been
T14959 31713-31718 VBN denotes shown
T14960 31719-31721 TO denotes to
T14961 31722-31724 VB denotes be
T14962 31725-31727 DT denotes an
T14963 31728-31737 JJ denotes important
T14964 31738-31744 NN denotes factor
T14965 31745-31747 IN denotes in
T14966 31748-31755 JJ denotes cardiac
T14967 31756-31757 NNP denotes [
T14968 31757-31759 CD denotes 15
T14969 31759-31760 NNP denotes ]
T14970 31760-31761 , denotes ,
T14971 31762-31770 JJ denotes neuronal
T14972 31771-31772 NNP denotes [
T14973 31772-31774 CD denotes 10
T14974 31774-31775 NNP denotes ]
T14975 31775-31776 , denotes ,
T14976 31777-31787 JJ denotes astrocytic
T14977 31788-31789 NNP denotes [
T14978 31789-31791 CD denotes 11
T14979 31791-31792 NNP denotes ]
T14980 31792-31793 , denotes ,
T14981 31794-31797 CC denotes and
T14982 31798-31807 NN denotes cartilage
T14983 31808-31823 NN denotes differentiation
T14984 31824-31832 NNS denotes programs
T14985 31833-31834 NNP denotes [
T14986 31834-31839 CD denotes 32,41
T14987 31840-31842 CD denotes 44
T14988 31842-31843 NN denotes ]
T14989 31843-31844 . denotes .
T14990 31845-31848 DT denotes The
T14991 31849-31860 NN denotes restoration
T14992 31861-31863 IN denotes of
T14993 31864-31870 JJ denotes normal
T14994 31871-31882 NN denotes enucleation
T14995 31883-31885 IN denotes of
T14996 31886-31889 JJ denotes red
T14997 31890-31895 NNS denotes cells
T14998 31896-31898 IN denotes in
T14999 31899-31913 JJ denotes Sox6-deficient
T15000 31914-31919 NN denotes mouse
T15001 31920-31922 IN denotes by
T15002 31923-31932 JJ denotes postnatal
T15003 31933-31936 NN denotes day
T15004 31937-31941 CD denotes 10.5
T15005 31942-31945 MD denotes may
T15006 31946-31952 VB denotes result
T15007 31953-31957 IN denotes from
T15008 31958-31968 JJ denotes functional
T15009 31969-31981 NN denotes compensation
T15010 31982-31984 IN denotes of
T15011 31985-31990 JJ denotes other
T15012 31991-31994 NNP denotes Sox
T15013 31995-32003 NNS denotes proteins
T15014 32004-32005 -LRB- denotes (
T15015 32005-32014 VBN denotes expressed
T15016 32015-32017 IN denotes at
T15017 32018-32023 JJ denotes later
T15018 32024-32037 JJ denotes developmental
T15019 32038-32044 NNS denotes stages
T15020 32044-32045 -RRB- denotes )
T15021 32045-32046 , denotes ,
T15022 32047-32052 IN denotes since
T15023 32053-32063 JJ denotes functional
T15024 32064-32074 NN denotes redundancy
T15025 32075-32077 VBZ denotes is
T15026 32078-32079 DT denotes a
T15027 32080-32089 VBG denotes recurring
T15028 32090-32095 NN denotes theme
T15029 32096-32100 IN denotes with
T15030 32101-32104 NNP denotes Sox
T15031 32105-32113 NNS denotes proteins
T15032 32114-32115 NNP denotes [
T15033 32115-32123 CD denotes 13,45,46
T15034 32123-32124 NNP denotes ]
T15035 32124-32125 . denotes .
T15036 32126-32134 RB denotes Moreover
T15037 32134-32135 , denotes ,
T15038 32136-32150 NN denotes erythropoiesis
T15039 32151-32154 VBZ denotes has
T15040 32155-32162 RB denotes already
T15041 32163-32170 VBN denotes shifted
T15042 32171-32175 IN denotes from
T15043 32176-32181 JJ denotes fetal
T15044 32182-32187 NN denotes liver
T15045 32188-32190 TO denotes to
T15046 32191-32195 NN denotes bone
T15047 32196-32202 NN denotes marrow
T15048 32203-32205 IN denotes by
T15049 32206-32215 JJ denotes postnatal
T15050 32216-32219 NN denotes day
T15051 32220-32224 CD denotes 10.5
T15052 32224-32225 . denotes .
T15053 32226-32229 DT denotes The
T15054 32230-32242 JJ denotes accompanying
T15055 32243-32249 NN denotes change
T15056 32250-32252 IN denotes in
T15057 32253-32256 DT denotes the
T15058 32257-32273 NN denotes microenvironment
T15059 32274-32276 IN denotes of
T15060 32277-32280 JJ denotes red
T15061 32281-32285 NN denotes cell
T15062 32286-32296 NN denotes production
T15063 32297-32300 MD denotes may
T15064 32301-32307 VB denotes permit
T15065 32308-32314 JJ denotes normal
T15066 32315-32326 NN denotes enucleation
T15067 32326-32327 . denotes .
T15068 32328-32342 NN denotes Identification
T15069 32343-32345 IN denotes of
T15070 32346-32350 JJ denotes Sox6
T15071 32351-32361 JJ denotes downstream
T15072 32362-32368 NN denotes target
T15073 32369-32374 NNS denotes genes
T15074 32375-32378 CC denotes and
T15075 32379-32382 PRP$ denotes its
T15076 32383-32394 VBG denotes interacting
T15077 32395-32403 NNS denotes proteins
T15078 32404-32408 MD denotes will
T15079 32409-32413 VB denotes shed
T15080 32414-32419 NN denotes light
T15081 32420-32422 IN denotes on
T15082 32423-32426 DT denotes the
T15083 32427-32431 NN denotes role
T15084 32432-32434 IN denotes of
T15085 32435-32439 NNP denotes Sox6
T15086 32440-32442 IN denotes in
T15087 32443-32446 JJ denotes red
T15088 32447-32451 NN denotes cell
T15089 32452-32460 NN denotes terminal
T15090 32461-32476 NN denotes differentiation
T15091 32477-32480 CC denotes and
T15092 32481-32484 DT denotes the
T15093 32485-32496 NN denotes enucleation
T15094 32497-32504 NN denotes process
T15095 32504-32505 . denotes .
T15096 32506-32514 RB denotes Recently
T15097 32514-32515 , denotes ,
T15098 32516-32518 IN denotes in
T15099 32519-32523 NN denotes vivo
T15100 32524-32527 CC denotes and
T15101 32528-32530 IN denotes in
T15102 32531-32536 NN denotes vitro
T15103 32537-32545 NNS denotes analyses
T15104 32546-32553 VBP denotes suggest
T15105 32554-32558 IN denotes that
T15106 32559-32571 NN denotes reactivation
T15107 32572-32574 IN denotes of
T15108 32575-32580 JJ denotes human
T15109 32581-32589 NN denotes ɛ-globin
T15110 32590-32595 MD denotes would
T15111 32596-32598 VB denotes be
T15112 32599-32614 RB denotes therapeutically
T15113 32615-32625 JJ denotes beneficial
T15114 32626-32628 TO denotes to
T15115 32629-32635 NNS denotes adults
T15116 32636-32640 IN denotes with
T15117 32641-32647 JJ denotes sickle
T15118 32648-32652 NN denotes cell
T15119 32653-32660 NN denotes disease
T15120 32661-32662 NNP denotes [
T15121 32662-32664 CD denotes 47
T15122 32664-32665 NNP denotes ]
T15123 32665-32666 , denotes ,
T15124 32667-32676 VBG denotes providing
T15125 32677-32678 DT denotes a
T15126 32679-32688 NN denotes rationale
T15127 32689-32692 IN denotes for
T15128 32693-32701 JJ denotes detailed
T15129 32702-32716 NNS denotes investigations
T15130 32717-32721 IN denotes into
T15131 32722-32725 DT denotes the
T15132 32726-32735 JJ denotes molecular
T15133 32736-32741 NN denotes basis
T15134 32742-32744 IN denotes of
T15135 32745-32753 JJ denotes ɛ-globin
T15136 32754-32758 NN denotes gene
T15137 32759-32768 VBG denotes silencing
T15138 32768-32769 . denotes .
T15139 32770-32773 DT denotes The
T15140 32774-32781 JJ denotes present
T15141 32782-32787 NN denotes study
T15142 32788-32798 VBZ denotes identifies
T15143 32799-32800 DT denotes a
T15144 32801-32806 NN denotes novel
T15145 32807-32816 NN denotes repressor
T15146 32816-32817 , denotes ,
T15147 32818-32822 NNP denotes Sox6
T15148 32822-32823 , denotes ,
T15149 32824-32829 WDT denotes which
T15150 32830-32835 VBZ denotes binds
T15151 32836-32838 TO denotes to
T15152 32839-32842 DT denotes the
T15153 32843-32845 JJ denotes ɛy
T15154 32846-32854 JJ denotes proximal
T15155 32855-32863 NN denotes promoter
T15156 32863-32864 , denotes ,
T15157 32865-32876 RB denotes potentially
T15158 32877-32879 IN denotes as
T15159 32880-32884 NN denotes part
T15160 32885-32887 IN denotes of
T15161 32888-32889 DT denotes a
T15162 32890-32896 JJR denotes larger
T15163 32897-32907 NN denotes repression
T15164 32908-32915 NN denotes complex
T15165 32915-32916 . denotes .
T15166 32917-32924 IN denotes Because
T15167 32925-32931 JJ denotes murine
T15168 32932-32936 NNP denotes Sox6
T15169 32937-32940 CC denotes and
T15170 32941-32944 PRP$ denotes its
T15171 32945-32950 JJ denotes human
T15172 32951-32962 NN denotes counterpart
T15173 32963-32966 VBP denotes are
T15174 32967-32969 CD denotes 94
T15175 32969-32970 NN denotes %
T15176 32971-32980 JJ denotes identical
T15177 32981-32983 IN denotes at
T15178 32984-32987 DT denotes the
T15179 32988-32993 JJ denotes amino
T15180 32994-32998 NN denotes acid
T15181 32999-33004 NN denotes level
T15182 33005-33006 NNP denotes [
T15183 33006-33008 CD denotes 48
T15184 33008-33009 NNP denotes ]
T15185 33009-33010 , denotes ,
T15186 33011-33013 PRP denotes it
T15187 33014-33016 VBZ denotes is
T15188 33017-33025 JJ denotes possible
T15189 33026-33030 IN denotes that
T15190 33031-33036 JJ denotes human
T15191 33037-33041 NNP denotes Sox6
T15192 33042-33045 MD denotes may
T15193 33046-33050 RB denotes also
T15194 33051-33053 VB denotes be
T15195 33054-33063 JJ denotes important
T15196 33064-33066 IN denotes in
T15197 33067-33072 JJ denotes human
T15198 33073-33074 NN denotes ɛ
T15199 33075-33081 NN denotes globin
T15200 33082-33091 VBG denotes silencing
T15201 33091-33092 . denotes .
T15202 33093-33098 EX denotes There
T15203 33099-33101 VBZ denotes is
T15204 33102-33113 JJ denotes significant
T15205 33114-33122 NN denotes sequence
T15206 33123-33131 NN denotes homology
T15207 33132-33139 IN denotes between
T15208 33140-33143 DT denotes the
T15209 33144-33149 JJ denotes human
T15210 33150-33153 CC denotes and
T15211 33154-33159 NN denotes mouse
T15212 33160-33161 NN denotes ɛ
T15213 33162-33170 NN denotes promoter
T15214 33171-33178 NNS denotes regions
T15215 33178-33179 , denotes ,
T15216 33180-33183 CC denotes and
T15217 33184-33187 DT denotes the
T15218 33188-33193 JJ denotes human
T15219 33194-33202 NN denotes promoter
T15220 33203-33211 VBZ denotes contains
T15221 33212-33214 IN denotes at
T15222 33215-33220 JJS denotes least
T15223 33221-33224 CD denotes two
T15224 33225-33234 JJ denotes potential
T15225 33235-33239 JJ denotes Sox6
T15226 33240-33247 JJ denotes binding
T15227 33248-33253 NNS denotes sites
T15228 33253-33254 . denotes .
T15229 33255-33261 RB denotes Indeed
T15230 33261-33262 , denotes ,
T15231 33263-33266 DT denotes the
T15232 33267-33276 NN denotes existence
T15233 33277-33279 IN denotes of
T15234 33280-33281 DT denotes a
T15235 33282-33290 NN denotes silencer
T15236 33291-33293 IN denotes of
T15237 33294-33297 DT denotes the
T15238 33298-33303 JJ denotes human
T15239 33304-33305 NN denotes ɛ
T15240 33306-33312 NN denotes globin
T15241 33313-33317 NN denotes gene
T15242 33318-33321 VBZ denotes has
T15243 33322-33326 VBN denotes been
T15244 33327-33335 VBN denotes proposed
T15245 33336-33337 NNP denotes [
T15246 33337-33342 CD denotes 49,50
T15247 33342-33343 NNP denotes ]
T15248 33343-33344 . denotes .
T15249 33345-33349 RB denotes Thus
T15250 33349-33350 , denotes ,
T15251 33351-33362 NN denotes elucidation
T15252 33363-33365 IN denotes of
T15253 33366-33369 DT denotes the
T15254 33370-33374 JJ denotes Sox6
T15255 33375-33385 NN denotes repression
T15256 33386-33395 NN denotes mechanism
T15257 33396-33399 CC denotes and
T15258 33400-33414 NN denotes identification
T15259 33415-33417 IN denotes of
T15260 33418-33423 JJ denotes other
T15261 33424-33434 NNS denotes components
T15262 33435-33437 IN denotes of
T15263 33438-33441 DT denotes the
T15264 33442-33457 JJ denotes Sox6-containing
T15265 33458-33465 NN denotes complex
T15266 33466-33469 MD denotes may
T15267 33470-33477 RB denotes further
T15268 33478-33481 PRP$ denotes our
T15269 33482-33495 NN denotes understanding
T15270 33496-33498 IN denotes of
T15271 33499-33500 NN denotes ɛ
T15272 33501-33507 NN denotes globin
T15273 33508-33518 NN denotes regulation
T15274 33519-33522 CC denotes and
T15275 33523-33534 RB denotes potentially
T15276 33535-33541 VB denotes reveal
T15277 33542-33552 JJ denotes additional
T15278 33553-33562 JJ denotes molecular
T15279 33563-33570 NNS denotes targets
T15280 33571-33574 IN denotes for
T15281 33575-33578 DT denotes the
T15282 33579-33588 NN denotes treatment
T15283 33589-33591 IN denotes of
T15284 33592-33598 NN denotes sickle
T15285 33599-33603 NN denotes cell
T15286 33604-33610 NN denotes anemia
T15287 33611-33614 CC denotes and
T15288 33615-33616 NN denotes β
T15289 33617-33629 NNS denotes thalassemias
T15290 33629-33630 . denotes .
T16562 33655-33662 JJ denotes Plasmid
T16563 33663-33675 NN denotes construction
T16564 33675-33676 . denotes .
T16565 33677-33680 DT denotes The
T16566 33681-33683 JJ denotes ɛy
T16567 33684-33692 NN denotes promoter
T16568 33693-33701 NN denotes deletion
T16569 33702-33710 NN denotes reporter
T16570 33711-33718 NN denotes plasmid
T16571 33719-33720 -LRB- denotes (
T16572 33720-33725 JJ denotes E-luc
T16573 33725-33726 -RRB- denotes )
T16574 33727-33730 VBD denotes was
T16575 33731-33740 VBN denotes generated
T16576 33741-33743 IN denotes by
T16577 33744-33747 NNP denotes PCR
T16578 33748-33761 NN denotes amplification
T16579 33762-33764 IN denotes of
T16580 33765-33768 DT denotes the
T16581 33769-33771 JJ denotes ɛy
T16582 33772-33780 JJ denotes proximal
T16583 33781-33789 NN denotes promoter
T16584 33789-33790 . denotes .
T16585 33791-33792 DT denotes A
T16586 33793-33799 JJ denotes 2.2-kb
T16587 33800-33808 NN denotes fragment
T16588 33809-33817 RB denotes upstream
T16589 33818-33820 IN denotes of
T16590 33821-33824 DT denotes the
T16591 33825-33827 JJ denotes ɛy
T16592 33828-33834 NN denotes globin
T16593 33835-33845 NN denotes initiation
T16594 33846-33851 NN denotes codon
T16595 33852-33853 -LRB- denotes (
T16596 33853-33856 NNP denotes ATG
T16597 33856-33857 -RRB- denotes )
T16598 33858-33861 VBD denotes was
T16599 33862-33866 VBN denotes used
T16600 33866-33867 , denotes ,
T16601 33868-33875 IN denotes because
T16602 33876-33878 PRP denotes it
T16603 33879-33882 VBZ denotes has
T16604 33883-33887 VBN denotes been
T16605 33888-33893 VBN denotes shown
T16606 33894-33898 IN denotes that
T16607 33899-33902 DT denotes all
T16608 33903-33912 NNS denotes sequences
T16609 33913-33921 VBN denotes required
T16610 33922-33925 IN denotes for
T16611 33926-33927 NN denotes ɛ
T16612 33928-33932 NN denotes gene
T16613 33933-33942 VBG denotes silencing
T16614 33943-33946 VBP denotes are
T16615 33947-33954 VBN denotes located
T16616 33955-33961 IN denotes within
T16617 33962-33963 DT denotes a
T16618 33964-33970 JJ denotes 3.7-kb
T16619 33971-33976 NNP denotes EcoRI
T16620 33977-33985 NN denotes fragment
T16621 33986-33996 VBG denotes containing
T16622 33997-34002 IN denotes about
T16623 34003-34004 CD denotes 2
T16624 34005-34007 NN denotes kb
T16625 34008-34010 IN denotes of
T16626 34011-34019 NN denotes sequence
T16627 34020-34028 RB denotes upstream
T16628 34029-34031 IN denotes of
T16629 34032-34035 DT denotes the
T16630 34036-34037 NN denotes ɛ
T16631 34038-34044 NN denotes globin
T16632 34045-34049 NN denotes gene
T16633 34050-34053 NN denotes cap
T16634 34054-34058 NN denotes site
T16635 34059-34060 NNP denotes [
T16636 34060-34062 CD denotes 50
T16637 34062-34063 NNP denotes ]
T16638 34063-34064 . denotes .
T16639 34065-34075 NNP denotes Nucleotide
T16640 34076-34085 NN denotes numbering
T16641 34086-34088 VBZ denotes is
T16642 34089-34097 JJ denotes relative
T16643 34098-34100 TO denotes to
T16644 34101-34104 DT denotes the
T16645 34105-34118 NN denotes transcription
T16646 34119-34124 VB denotes start
T16647 34125-34129 NN denotes site
T16648 34129-34130 . denotes .
T16649 34131-34134 DT denotes The
T16650 34135-34150 JJ denotes transcriptional
T16651 34151-34156 NN denotes start
T16652 34157-34161 NN denotes site
T16653 34162-34164 VBZ denotes is
T16654 34165-34170 VBN denotes based
T16655 34171-34173 IN denotes on
T16656 34174-34177 DT denotes the
T16657 34178-34185 JJS denotes longest
T16658 34186-34190 NN denotes cDNA
T16659 34191-34193 IN denotes in
T16660 34194-34197 DT denotes the
T16661 34198-34204 NNP denotes Fantom
T16662 34205-34206 -LRB- denotes (
T16663 34206-34216 NNP denotes Functional
T16664 34217-34227 NNP denotes Annotation
T16665 34228-34230 IN denotes of
T16666 34231-34236 NNP denotes Mouse
T16667 34236-34237 -RRB- denotes )
T16668 34238-34246 NN denotes database
T16669 34246-34247 . denotes .
T16670 34248-34251 DT denotes The
T16671 34252-34255 NNP denotes PCR
T16672 34256-34263 NNS denotes primers
T16673 34264-34273 VBD denotes contained
T16674 34274-34278 NNP denotes XhoI
T16675 34279-34282 CC denotes and
T16676 34283-34290 NNP denotes HindIII
T16677 34291-34296 NNS denotes sites
T16678 34297-34301 WDT denotes that
T16679 34302-34306 VBD denotes were
T16680 34307-34311 VBN denotes used
T16681 34312-34314 TO denotes to
T16682 34315-34320 VB denotes clone
T16683 34321-34324 DT denotes the
T16684 34325-34327 JJ denotes ɛy
T16685 34328-34336 NN denotes promoter
T16686 34337-34345 NN denotes fragment
T16687 34346-34354 RB denotes upstream
T16688 34355-34357 IN denotes of
T16689 34358-34361 DT denotes the
T16690 34362-34369 JJ denotes firefly
T16691 34370-34380 NN denotes luciferase
T16692 34381-34385 NN denotes gene
T16693 34386-34388 IN denotes in
T16694 34389-34393 NNP denotes pGL3
T16695 34394-34399 NNP denotes Basic
T16696 34400-34401 -LRB- denotes (
T16697 34401-34408 NNP denotes Promega
T16698 34408-34409 , denotes ,
T16699 34410-34417 NNP denotes Madison
T16700 34417-34418 , denotes ,
T16701 34419-34428 NNP denotes Wisconsin
T16702 34428-34429 , denotes ,
T16703 34430-34436 NNP denotes United
T16704 34437-34443 NNPS denotes States
T16705 34443-34444 -RRB- denotes )
T16706 34444-34445 . denotes .
T16707 34446-34447 DT denotes A
T16708 34448-34454 JJ denotes 2.5-kb
T16709 34455-34464 NNP denotes SstI/XhoI
T16710 34465-34473 NN denotes fragment
T16711 34474-34476 IN denotes of
T16712 34477-34482 NNP denotes μLCRβ
T16713 34483-34486 CD denotes 9.3
T16714 34487-34488 -LRB- denotes (
T16715 34488-34493 NN denotes micro
T16716 34494-34497 NNP denotes LCR
T16717 34497-34498 : denotes ;
T16718 34499-34500 NNP denotes [
T16719 34500-34502 CD denotes 31
T16720 34502-34503 NNP denotes ]
T16721 34503-34504 -RRB- denotes )
T16722 34505-34508 VBD denotes was
T16723 34509-34513 RB denotes then
T16724 34514-34522 VBN denotes inserted
T16725 34523-34531 RB denotes upstream
T16726 34532-34534 IN denotes of
T16727 34535-34538 DT denotes the
T16728 34539-34541 JJ denotes ɛy
T16729 34542-34550 NN denotes promoter
T16730 34551-34553 IN denotes in
T16731 34554-34557 DT denotes the
T16732 34558-34563 JJ denotes above
T16733 34564-34568 JJ denotes pGL3
T16734 34569-34574 JJ denotes Basic
T16735 34575-34582 NN denotes plasmid
T16736 34582-34583 , denotes ,
T16737 34584-34593 VBG denotes resulting
T16738 34594-34596 IN denotes in
T16739 34597-34598 DT denotes a
T16740 34599-34607 NN denotes reporter
T16741 34608-34617 VB denotes construct
T16742 34618-34620 IN denotes in
T16743 34621-34626 WDT denotes which
T16744 34627-34637 NN denotes luciferase
T16745 34638-34648 NN denotes expression
T16746 34649-34651 VBZ denotes is
T16747 34652-34658 VBN denotes driven
T16748 34659-34661 IN denotes by
T16749 34662-34665 DT denotes the
T16750 34666-34668 JJ denotes ɛy
T16751 34669-34677 NN denotes promoter
T16752 34677-34678 . denotes .
T16753 34679-34680 DT denotes A
T16754 34681-34687 NN denotes series
T16755 34688-34690 IN denotes of
T16756 34691-34699 NN denotes deletion
T16757 34700-34710 NNS denotes constructs
T16758 34711-34713 IN denotes of
T16759 34714-34717 DT denotes the
T16760 34718-34720 JJ denotes ɛy
T16761 34721-34729 NN denotes promoter
T16762 34730-34734 VBD denotes were
T16763 34735-34744 VBN denotes generated
T16764 34745-34754 RB denotes similarly
T16765 34754-34755 . denotes .
T16766 34756-34763 RB denotes Forward
T16767 34764-34771 NNS denotes primers
T16768 34772-34776 IN denotes with
T16769 34777-34779 DT denotes an
T16770 34780-34784 NNP denotes XhoI
T16771 34785-34789 NN denotes site
T16772 34790-34797 VBP denotes include
T16773 34797-34798 : denotes :
T16774 34799-34806 NNP denotes MHB1457
T16775 34806-34807 , denotes ,
T16776 34808-34809 CD denotes 5
T16777 34809-34810 NN denotes ′
T16778 34810-34837 CD denotes CCGCTCGAGTGCTAGGCAAACACTCA3
T16779 34837-34838 NN denotes ′
T16780 34839-34840 -LRB- denotes (
T16781 34840-34841 FW denotes −
T16782 34841-34845 CD denotes 2077
T16783 34846-34848 TO denotes to
T16784 34849-34850 CD denotes −
T16785 34850-34854 CD denotes 2052
T16786 34854-34855 -RRB- denotes )
T16787 34855-34856 : denotes ;
T16788 34857-34864 NNP denotes MHB1503
T16789 34864-34865 , denotes ,
T16790 34866-34867 CD denotes 5
T16791 34867-34868 NN denotes ′
T16792 34868-34899 CD denotes CCGCTCGAGTCTCTACACTGTCACTCCCTG3
T16793 34899-34900 NN denotes ′
T16794 34901-34902 -LRB- denotes (
T16795 34902-34903 FW denotes −
T16796 34903-34906 CD denotes 634
T16797 34907-34909 TO denotes to
T16798 34910-34911 CD denotes −
T16799 34911-34914 CD denotes 605
T16800 34914-34915 -RRB- denotes )
T16801 34915-34916 : denotes ;
T16802 34917-34924 NNP denotes MHB1505
T16803 34924-34925 , denotes ,
T16804 34926-34927 CD denotes 5
T16805 34927-34928 NN denotes ′
T16806 34928-34957 CD denotes CCGCTCGAGGGAGCCAAAAAAAGAATGC3
T16807 34957-34958 NN denotes ′
T16808 34959-34960 -LRB- denotes (
T16809 34960-34961 FW denotes −
T16810 34961-34964 CD denotes 197
T16811 34965-34967 TO denotes to
T16812 34968-34969 CD denotes −
T16813 34969-34972 CD denotes 169
T16814 34972-34973 -RRB- denotes )
T16815 34973-34974 : denotes ;
T16816 34975-34982 NNP denotes MHB1506
T16817 34982-34983 , denotes ,
T16818 34984-34985 CD denotes 5
T16819 34985-34986 NN denotes ′
T16820 34986-35015 CD denotes CCGCTCGAGCTGACCAATGGCTTCAAAG3
T16821 35015-35016 NN denotes ′
T16822 35017-35018 -LRB- denotes (
T16823 35018-35019 FW denotes −
T16824 35019-35021 CD denotes 85
T16825 35022-35024 TO denotes to
T16826 35025-35026 CD denotes −
T16827 35026-35028 CD denotes 58
T16828 35028-35029 -RRB- denotes )
T16829 35029-35030 : denotes ;
T16830 35031-35038 NNP denotes MHB1532
T16831 35038-35039 , denotes ,
T16832 35040-35041 CD denotes 5
T16833 35041-35042 NN denotes ′
T16834 35042-35073 CD denotes CCGCTCGAGAATGCAGAACAAAGGGTCAGA3
T16835 35073-35074 NN denotes ′
T16836 35075-35076 -LRB- denotes (
T16837 35076-35077 FW denotes −
T16838 35077-35079 CD denotes 63
T16839 35080-35082 TO denotes to
T16840 35083-35084 CD denotes −
T16841 35084-35086 CD denotes 34
T16842 35086-35087 -RRB- denotes )
T16843 35087-35088 : denotes ;
T16844 35089-35092 CC denotes and
T16845 35093-35100 NNP denotes MHB1507
T16846 35100-35101 , denotes ,
T16847 35102-35103 CD denotes 5
T16848 35103-35104 NN denotes ′
T16849 35104-35133 NNP denotes CCGCTCGAGGTCTGCGAAGAATAAAAGGC
T16850 35134-35135 CD denotes 3
T16851 35135-35136 NN denotes ′
T16852 35137-35138 -LRB- denotes (
T16853 35138-35139 FW denotes −
T16854 35139-35141 CD denotes 37
T16855 35142-35144 TO denotes to
T16856 35145-35146 CD denotes −
T16857 35146-35147 CD denotes 9
T16858 35147-35148 -RRB- denotes )
T16859 35148-35149 . denotes .
T16860 35150-35153 DT denotes All
T16861 35154-35161 RB denotes forward
T16862 35162-35169 NNS denotes primers
T16863 35170-35174 VBD denotes were
T16864 35175-35179 VBN denotes used
T16865 35180-35182 IN denotes in
T16866 35183-35194 NN denotes combination
T16867 35195-35199 IN denotes with
T16868 35200-35203 DT denotes the
T16869 35204-35211 NN denotes reverse
T16870 35212-35218 NN denotes primer
T16871 35219-35226 NNP denotes HindIII
T16872 35227-35231 NN denotes site
T16873 35231-35232 : denotes :
T16874 35233-35240 NNP denotes MHB1477
T16875 35240-35241 , denotes ,
T16876 35242-35243 CD denotes 5
T16877 35243-35244 NN denotes ′
T16878 35244-35270 CD denotes CGGAAGCTTGGGAGGTTGCTGGTGA3
T16879 35270-35271 NN denotes ′
T16880 35272-35273 -LRB- denotes (
T16881 35273-35276 CD denotes +45
T16882 35277-35279 TO denotes to
T16883 35280-35283 CD denotes +20
T16884 35283-35284 -RRB- denotes )
T16885 35284-35285 . denotes .
T16886 35286-35297 JJ denotes Sox6-pcDNA3
T16887 35297-35299 CD denotes .1
T16888 35300-35301 NNP denotes [
T16889 35301-35303 CD denotes 15
T16890 35303-35304 NNP denotes ]
T16891 35305-35308 VBD denotes was
T16892 35309-35313 VBN denotes used
T16893 35314-35316 TO denotes to
T16894 35317-35328 VB denotes overexpress
T16895 35329-35333 NNP denotes Sox6
T16896 35333-35334 . denotes .
T16897 35335-35336 DT denotes A
T16898 35337-35346 VBN denotes truncated
T16899 35347-35354 NN denotes version
T16900 35355-35357 IN denotes of
T16901 35358-35361 DT denotes the
T16902 35362-35366 JJ denotes Sox6
T16903 35367-35381 NN denotes overexpression
T16904 35382-35391 VBP denotes construct
T16905 35392-35393 -LRB- denotes (
T16906 35393-35409 JJ denotes Sox6-ΔHMG-pcDNA3
T16907 35409-35411 CD denotes .1
T16908 35411-35412 -RRB- denotes )
T16909 35413-35417 WDT denotes that
T16910 35418-35423 VBZ denotes lacks
T16911 35424-35427 DT denotes the
T16912 35428-35431 NNP denotes HMG
T16913 35432-35438 NN denotes domain
T16914 35439-35442 VBD denotes was
T16915 35443-35452 VBN denotes generated
T16916 35452-35453 , denotes ,
T16917 35454-35456 IN denotes as
T16918 35457-35466 VBN denotes described
T16919 35467-35469 IN denotes by
T16920 35470-35476 NNS denotes others
T16921 35477-35478 NNP denotes [
T16922 35478-35480 CD denotes 32
T16923 35480-35481 NNP denotes ]
T16924 35481-35482 . denotes .
T16925 35483-35494 NNP denotes Mutagenesis
T16926 35495-35497 IN denotes of
T16927 35498-35506 NNP denotes Sox/Sox6
T16928 35507-35516 NN denotes consensus
T16929 35517-35524 JJ denotes binding
T16930 35525-35530 NNS denotes sites
T16931 35531-35533 IN denotes of
T16932 35534-35537 DT denotes the
T16933 35538-35540 JJ denotes ɛy
T16934 35541-35549 NN denotes promoter
T16935 35550-35554 VBD denotes were
T16936 35555-35559 VBN denotes done
T16937 35560-35562 IN denotes by
T16938 35563-35566 NNP denotes PCR
T16939 35566-35567 . denotes .
T16940 35568-35575 RB denotes Forward
T16941 35576-35583 NNS denotes primers
T16942 35584-35588 VBN denotes used
T16943 35589-35591 TO denotes to
T16944 35592-35600 VB denotes generate
T16945 35601-35606 DT denotes these
T16946 35607-35618 VBN denotes mutagenized
T16947 35619-35621 NN denotes ɛy
T16948 35622-35630 NN denotes promoter
T16949 35631-35639 NN denotes reporter
T16950 35640-35650 NNS denotes constructs
T16951 35651-35658 VBP denotes include
T16952 35658-35659 : denotes :
T16953 35660-35667 CD denotes MHB1661
T16954 35667-35668 , denotes ,
T16955 35669-35670 CD denotes 5
T16956 35670-35671 NN denotes ′
T16957 35671-35717 CD denotes CCGCTCGAGAATGCAGTGCCAAGGGTCAGAACATTGTCTGCGAAG3
T16958 35717-35718 NN denotes ′
T16959 35719-35720 -LRB- denotes (
T16960 35720-35721 FW denotes −
T16961 35721-35723 CD denotes 63
T16962 35724-35726 TO denotes to
T16963 35727-35728 CD denotes −
T16964 35728-35730 CD denotes 19
T16965 35730-35731 -RRB- denotes )
T16966 35731-35732 : denotes ;
T16967 35733-35740 NNP denotes MHB1662
T16968 35740-35741 , denotes ,
T16969 35742-35743 CD denotes 5
T16970 35743-35744 NN denotes ′
T16971 35744-35792 CD denotes CCGCTCGAGAATGCAGAACAAAGGGTCAGATGAGTGTCTGCGAAGAA3
T16972 35792-35793 NN denotes ′
T16973 35794-35795 -LRB- denotes (
T16974 35795-35796 FW denotes −
T16975 35796-35798 CD denotes 63
T16976 35799-35801 TO denotes to
T16977 35802-35803 CD denotes −
T16978 35803-35805 CD denotes 16
T16979 35805-35806 -RRB- denotes )
T16980 35806-35807 : denotes ;
T16981 35808-35811 CC denotes and
T16982 35812-35819 NNP denotes MHB1663
T16983 35819-35820 , denotes ,
T16984 35821-35822 CD denotes 5
T16985 35822-35823 NN denotes ′
T16986 35823-35869 NNP denotes CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA
T16987 35870-35871 CD denotes 3
T16988 35871-35872 NN denotes ′
T16989 35873-35874 -LRB- denotes (
T16990 35874-35875 FW denotes −
T16991 35875-35877 CD denotes 63
T16992 35878-35880 TO denotes to
T16993 35881-35882 CD denotes −
T16994 35882-35884 CD denotes 18
T16995 35884-35885 -RRB- denotes )
T16996 35885-35886 . denotes .
T17438 35888-35900 NN denotes Quantitation
T17439 35901-35903 IN denotes of
T17440 35904-35910 NN denotes globin
T17441 35911-35915 NNP denotes mRNA
T17442 35915-35916 . denotes .
T17443 35917-35920 NNP denotes RNA
T17444 35921-35924 VBD denotes was
T17445 35925-35930 JJ denotes first
T17446 35931-35938 JJ denotes reverse
T17447 35939-35950 VBN denotes transcribed
T17448 35951-35953 TO denotes to
T17449 35954-35958 NNP denotes cDNA
T17450 35958-35959 . denotes .
T17451 35960-35967 NNS denotes Primers
T17452 35968-35971 IN denotes for
T17453 35972-35976 NNP denotes cDNA
T17454 35977-35980 NNP denotes PCR
T17455 35981-35994 NN denotes amplification
T17456 35995-35997 IN denotes of
T17457 35998-36004 NN denotes globin
T17458 36005-36010 NNS denotes genes
T17459 36011-36015 VBD denotes were
T17460 36016-36024 VBN denotes obtained
T17461 36025-36029 IN denotes from
T17462 36030-36040 NNP denotes Primerbank
T17463 36041-36042 NNP denotes [
T17464 36042-36044 CD denotes 51
T17465 36044-36045 NNP denotes ]
T17466 36045-36046 . denotes .
T17467 36047-36050 DT denotes All
T17468 36051-36058 NNS denotes primers
T17469 36059-36063 VBD denotes were
T17470 36064-36072 VBN denotes searched
T17471 36073-36080 IN denotes against
T17472 36081-36084 DT denotes the
T17473 36085-36089 NNP denotes NCBI
T17474 36090-36098 NN denotes database
T17475 36099-36101 TO denotes to
T17476 36102-36109 VB denotes confirm
T17477 36110-36121 NN denotes specificity
T17478 36121-36122 . denotes .
T17479 36123-36126 IN denotes For
T17480 36127-36129 JJ denotes ɛy
T17481 36130-36136 NN denotes globin
T17482 36136-36137 : denotes :
T17483 36138-36145 NNP denotes MHB1666
T17484 36145-36146 , denotes ,
T17485 36147-36148 CD denotes 5
T17486 36148-36149 CD denotes ′
T17487 36149-36171 CD denotes TGGCCTGTGGAGTAAGGTCAA3
T17488 36171-36172 NN denotes ′
T17489 36172-36173 : denotes ;
T17490 36174-36177 CC denotes and
T17491 36178-36185 NNP denotes MHB1667
T17492 36185-36186 , denotes ,
T17493 36187-36188 CD denotes 5
T17494 36188-36189 CD denotes ′
T17495 36189-36211 NNP denotes GAAGCAGAGGACAAGTTCCCA3
T17496 36211-36212 NN denotes ′
T17497 36212-36213 . denotes .
T17498 36214-36217 IN denotes For
T17499 36218-36219 JJ denotes ζ
T17500 36220-36226 NN denotes globin
T17501 36226-36227 : denotes :
T17502 36228-36235 CD denotes MHB1668
T17503 36235-36236 , denotes ,
T17504 36237-36238 CD denotes 5
T17505 36238-36239 NN denotes ′
T17506 36239-36261 CD denotes CTACCCCCAGACGAAGACCTA3
T17507 36261-36262 NN denotes ′
T17508 36262-36263 : denotes ;
T17509 36264-36267 CC denotes and
T17510 36268-36275 NNP denotes MHB1669
T17511 36275-36276 , denotes ,
T17512 36277-36278 CD denotes 5
T17513 36278-36279 NN denotes ′
T17514 36279-36300 CD denotes CTTAACCGCATCCCCTACGG3
T17515 36300-36301 NN denotes ′
T17516 36301-36302 . denotes .
T17517 36303-36306 IN denotes For
T17518 36307-36310 JJ denotes βH1
T17519 36311-36317 NN denotes globin
T17520 36317-36318 : denotes :
T17521 36319-36326 NNP denotes MHB1672
T17522 36326-36327 , denotes ,
T17523 36328-36329 CD denotes 5
T17524 36329-36330 CD denotes ′
T17525 36330-36351 CD denotes TGGACAACCTCAAGGAGACC3
T17526 36351-36352 NN denotes ′
T17527 36352-36353 : denotes ;
T17528 36354-36357 CC denotes and
T17529 36358-36365 NNP denotes MHB1673
T17530 36365-36366 , denotes ,
T17531 36367-36368 CD denotes 5
T17532 36368-36369 CD denotes ′
T17533 36369-36390 NNP denotes ACCTCTGGGGTGAATTCCTT3
T17534 36390-36391 NN denotes ′
T17535 36391-36392 . denotes .
T17536 36393-36396 IN denotes For
T17537 36397-36401 JJ denotes βmaj
T17538 36401-36402 NN denotes /
T17539 36402-36405 NN denotes min
T17540 36406-36412 NN denotes globin
T17541 36412-36413 : denotes :
T17542 36414-36421 NNP denotes MHB1674
T17543 36421-36422 : denotes :
T17544 36423-36424 CD denotes 5
T17545 36424-36425 CD denotes ′
T17546 36425-36446 NNP denotes ATGGCCTGAATCACTTGGAC3
T17547 36446-36447 NN denotes ′
T17548 36447-36448 : denotes ;
T17549 36449-36452 CC denotes and
T17550 36453-36460 NNP denotes MHB1675
T17551 36460-36461 , denotes ,
T17552 36462-36463 CD denotes 5
T17553 36463-36464 CD denotes ′
T17554 36464-36485 NNP denotes ACGATCATATTGCCCAGGAG3
T17555 36485-36486 NN denotes ′
T17556 36486-36487 . denotes .
T17557 36488-36493 VBG denotes Using
T17558 36494-36497 DT denotes the
T17559 36498-36502 NNP denotes SYBR
T17560 36503-36508 JJ denotes green
T17561 36509-36517 NN denotes supermix
T17562 36518-36521 NN denotes kit
T17563 36522-36526 IN denotes with
T17564 36527-36530 NNP denotes ROX
T17565 36531-36532 -LRB- denotes (
T17566 36532-36539 NNP denotes Bio-Rad
T17567 36539-36540 , denotes ,
T17568 36541-36549 NNP denotes Hercules
T17569 36549-36550 , denotes ,
T17570 36551-36561 NNP denotes California
T17571 36561-36562 , denotes ,
T17572 36563-36569 NNP denotes United
T17573 36570-36576 NNPS denotes States
T17574 36576-36577 -RRB- denotes )
T17575 36577-36578 , denotes ,
T17576 36579-36582 NNP denotes PCR
T17577 36583-36596 NN denotes amplification
T17578 36597-36600 VBD denotes was
T17579 36601-36604 VBN denotes run
T17580 36605-36607 IN denotes on
T17581 36608-36610 DT denotes an
T17582 36611-36618 NNP denotes ABI7000
T17583 36619-36620 -LRB- denotes (
T17584 36620-36627 NNP denotes Applied
T17585 36628-36638 NNPS denotes Biosystems
T17586 36638-36639 , denotes ,
T17587 36640-36646 NNP denotes Foster
T17588 36647-36651 NNP denotes City
T17589 36651-36652 , denotes ,
T17590 36653-36663 NNP denotes California
T17591 36663-36664 , denotes ,
T17592 36665-36671 NNP denotes United
T17593 36672-36678 NNPS denotes States
T17594 36678-36679 -RRB- denotes )
T17595 36680-36682 IN denotes at
T17596 36683-36686 DT denotes the
T17597 36687-36697 NNP denotes University
T17598 36698-36700 IN denotes of
T17599 36701-36708 NNP denotes Arizona
T17600 36709-36713 NN denotes core
T17601 36714-36722 NN denotes facility
T17602 36722-36723 . denotes .
T17603 36724-36727 DT denotes All
T17604 36728-36731 NNP denotes PCR
T17605 36732-36735 VBD denotes was
T17606 36736-36745 VBN denotes performed
T17607 36746-36748 IN denotes in
T17608 36749-36750 DT denotes a
T17609 36751-36756 JJ denotes 25-μl
T17610 36757-36765 NN denotes reaction
T17611 36766-36770 IN denotes with
T17612 36771-36775 CD denotes 12.5
T17613 36776-36778 NN denotes μl
T17614 36779-36783 NNP denotes SYBR
T17615 36784-36789 JJ denotes green
T17616 36790-36798 NN denotes supermix
T17617 36798-36799 . denotes .
T17618 36800-36805 NNP denotes GAPDH
T17619 36806-36810 NNP denotes mRNA
T17620 36811-36817 NNS denotes levels
T17621 36818-36822 VBD denotes were
T17622 36823-36827 VBN denotes used
T17623 36828-36830 IN denotes as
T17624 36831-36838 NN denotes control
T17625 36839-36842 IN denotes for
T17626 36843-36848 NN denotes input
T17627 36849-36852 NNP denotes RNA
T17628 36852-36853 . denotes .
T17629 36854-36862 NNP denotes Standard
T17630 36863-36868 NN denotes curve
T17631 36869-36877 NNS denotes analyses
T17632 36878-36882 VBD denotes were
T17633 36883-36892 VBN denotes performed
T17634 36893-36895 TO denotes to
T17635 36896-36900 VB denotes test
T17636 36901-36904 DT denotes the
T17637 36905-36915 NN denotes efficiency
T17638 36916-36918 IN denotes of
T17639 36919-36922 DT denotes the
T17640 36923-36937 NNS denotes amplifications
T17641 36937-36938 . denotes .
T17642 36939-36950 NNS denotes Triplicates
T17643 36951-36955 VBD denotes were
T17644 36956-36960 VBN denotes done
T17645 36961-36964 IN denotes for
T17646 36965-36969 DT denotes each
T17647 36970-36973 NNP denotes PCR
T17648 36974-36982 NN denotes reaction
T17649 36982-36983 . denotes .
T17650 36984-36992 JJ denotes Relative
T17651 36993-37005 JJ denotes quantitative
T17652 37006-37012 NNS denotes values
T17653 37013-37017 VBD denotes were
T17654 37018-37028 VBN denotes calculated
T17655 37029-37031 IN denotes in
T17656 37032-37035 DT denotes the
T17657 37036-37039 NNP denotes ABI
T17658 37040-37045 NNP denotes Prism
T17659 37046-37050 CD denotes 7000
T17660 37051-37054 NNP denotes SDS
T17661 37055-37063 NNP denotes Software
T17662 37064-37065 -LRB- denotes (
T17663 37065-37072 NNP denotes Applied
T17664 37073-37083 NNPS denotes Biosystems
T17665 37083-37084 -RRB- denotes )
T17666 37085-37088 CC denotes and
T17667 37089-37099 VBN denotes normalized
T17668 37100-37102 TO denotes to
T17669 37103-37108 NNP denotes GAPDH
T17670 37109-37111 IN denotes in
T17671 37112-37121 NNP denotes Microsoft
T17672 37122-37127 NNP denotes Excel
T17673 37128-37129 -LRB- denotes (
T17674 37129-37136 NNP denotes Redmond
T17675 37136-37137 , denotes ,
T17676 37138-37148 NNP denotes Washington
T17677 37148-37149 , denotes ,
T17678 37150-37156 NNP denotes United
T17679 37157-37163 NNPS denotes States
T17680 37163-37164 -RRB- denotes )
T17681 37164-37165 . denotes .
T17961 37167-37169 IN denotes In
T17962 37170-37174 NN denotes situ
T17963 37175-37188 NN denotes hybridization
T17964 37188-37189 . denotes .
T17965 37190-37199 JJ denotes Antisense
T17966 37200-37206 NNS denotes probes
T17967 37207-37211 VBD denotes were
T17968 37212-37220 VBN denotes designed
T17969 37221-37223 TO denotes to
T17970 37224-37230 VB denotes murine
T17971 37231-37233 JJ denotes ɛy
T17972 37234-37240 NN denotes globin
T17973 37241-37252 NNS denotes nucleotides
T17974 37253-37256 CD denotes 509
T17975 37257-37260 CD denotes 584
T17976 37260-37261 : denotes ;
T17977 37262-37266 NN denotes βmaj
T17978 37267-37273 NN denotes globin
T17979 37274-37285 NNS denotes nucleotides
T17980 37286-37289 CD denotes 458
T17981 37290-37293 CD denotes 549
T17982 37293-37294 : denotes ;
T17983 37295-37298 CC denotes and
T17984 37299-37304 NN denotes mouse
T17985 37305-37309 JJ denotes Sox6
T17986 37310-37321 NNS denotes nucleotides
T17987 37322-37326 CD denotes 1353
T17988 37327-37331 CD denotes 1927
T17989 37331-37332 . denotes .
T17990 37333-37340 NNS denotes Embryos
T17991 37341-37345 VBD denotes were
T17992 37346-37351 VBN denotes fixed
T17993 37352-37361 RB denotes overnight
T17994 37362-37364 IN denotes by
T17995 37365-37374 NN denotes immersion
T17996 37375-37377 IN denotes in
T17997 37378-37379 CD denotes 4
T17998 37379-37380 NN denotes %
T17999 37381-37397 NN denotes paraformaldehyde
T18000 37397-37398 , denotes ,
T18001 37399-37407 VBN denotes embedded
T18002 37408-37410 IN denotes in
T18003 37411-37419 NN denotes paraffin
T18004 37419-37420 , denotes ,
T18005 37421-37430 VBN denotes sectioned
T18006 37431-37433 IN denotes at
T18007 37434-37435 CD denotes 5
T18008 37436-37438 NN denotes μm
T18009 37438-37439 , denotes ,
T18010 37440-37443 CC denotes and
T18011 37444-37451 VBD denotes adhered
T18012 37452-37454 TO denotes to
T18013 37455-37461 VB denotes charge
T18014 37462-37470 VBN denotes modified
T18015 37471-37477 NNS denotes slides
T18016 37478-37479 -LRB- denotes (
T18017 37479-37482 NNP denotes VWR
T18018 37482-37483 , denotes ,
T18019 37484-37488 NNP denotes West
T18020 37489-37496 NNP denotes Chester
T18021 37496-37497 , denotes ,
T18022 37498-37510 NNP denotes Pennsylvania
T18023 37510-37511 , denotes ,
T18024 37512-37518 NNP denotes United
T18025 37519-37525 NNPS denotes States
T18026 37525-37526 -RRB- denotes )
T18027 37526-37527 . denotes .
T18028 37528-37534 NNS denotes Slides
T18029 37535-37539 VBD denotes were
T18030 37540-37549 VBN denotes processed
T18031 37550-37553 IN denotes for
T18032 37554-37556 IN denotes in
T18033 37557-37561 NN denotes situ
T18034 37562-37575 NN denotes hybridization
T18035 37576-37578 IN denotes as
T18036 37579-37588 VBN denotes described
T18037 37589-37590 NNP denotes [
T18038 37590-37592 CD denotes 52
T18039 37592-37593 NNP denotes ]
T18040 37594-37599 VBG denotes using
T18041 37600-37602 IN denotes in
T18042 37603-37608 NN denotes vitro
T18043 37609-37620 VBN denotes transcribed
T18044 37621-37624 NNP denotes RNA
T18045 37625-37631 NNS denotes probes
T18046 37632-37639 VBN denotes labeled
T18047 37640-37644 IN denotes with
T18048 37645-37648 NNP denotes 33P
T18049 37648-37649 . denotes .
T18050 37650-37659 NNP denotes Darkfield
T18051 37660-37663 CC denotes and
T18052 37664-37675 JJ denotes brightfield
T18053 37676-37682 NNS denotes images
T18054 37683-37687 VBD denotes were
T18055 37688-37696 VBN denotes obtained
T18056 37697-37701 IN denotes with
T18057 37702-37703 DT denotes a
T18058 37704-37709 NNP denotes Nikon
T18059 37710-37718 NNP denotes Optiphot
T18060 37719-37729 NN denotes microscope
T18061 37730-37731 -LRB- denotes (
T18062 37731-37736 NNP denotes Nikon
T18063 37736-37737 , denotes ,
T18064 37738-37746 NNP denotes Melville
T18065 37746-37747 , denotes ,
T18066 37748-37751 NNP denotes New
T18067 37752-37756 NNP denotes York
T18068 37756-37757 , denotes ,
T18069 37758-37764 NNP denotes United
T18070 37765-37771 NNPS denotes States
T18071 37771-37772 -RRB- denotes )
T18072 37773-37776 CC denotes and
T18073 37777-37781 NNP denotes SPOT
T18074 37782-37791 JJ denotes RT-Slider
T18075 37792-37799 JJ denotes digital
T18076 37800-37806 NN denotes camera
T18077 37807-37808 -LRB- denotes (
T18078 37808-37818 NNP denotes Diagnostic
T18079 37819-37830 NNP denotes Instruments
T18080 37830-37831 , denotes ,
T18081 37832-37840 NNP denotes Sterling
T18082 37841-37848 NNP denotes Heights
T18083 37848-37849 , denotes ,
T18084 37850-37858 NNP denotes Michigan
T18085 37858-37859 , denotes ,
T18086 37860-37866 NNP denotes United
T18087 37867-37873 NNPS denotes States
T18088 37873-37874 -RRB- denotes )
T18089 37874-37875 . denotes .
T18090 37876-37886 NNS denotes Objectives
T18091 37887-37891 VBN denotes used
T18092 37892-37896 VBD denotes were
T18093 37897-37898 CD denotes 1
T18094 37898-37899 NN denotes ×
T18095 37900-37901 -LRB- denotes (
T18096 37901-37903 NNP denotes NA
T18097 37904-37905 SYM denotes =
T18098 37906-37910 CD denotes 0.04
T18099 37910-37911 -RRB- denotes )
T18100 37912-37915 CC denotes and
T18101 37916-37918 CD denotes 10
T18102 37918-37919 NN denotes ×
T18103 37920-37921 -LRB- denotes (
T18104 37921-37923 NNP denotes NA
T18105 37924-37925 SYM denotes =
T18106 37926-37929 CD denotes 0.5
T18107 37929-37930 -RRB- denotes )
T18108 37930-37931 . denotes .
T18109 37932-37938 NNS denotes Images
T18110 37939-37943 VBD denotes were
T18111 37944-37953 VBN denotes processed
T18112 37953-37954 , denotes ,
T18113 37955-37968 VBN denotes pseudocolored
T18114 37968-37969 , denotes ,
T18115 37970-37973 CC denotes and
T18116 37974-37982 VBN denotes combined
T18117 37983-37988 VBG denotes using
T18118 37989-37998 NNP denotes Photoshop
T18119 37999-38000 -LRB- denotes (
T18120 38000-38005 NNP denotes Adobe
T18121 38005-38006 , denotes ,
T18122 38007-38010 NNP denotes San
T18123 38011-38015 NNP denotes Jose
T18124 38015-38016 , denotes ,
T18125 38017-38027 NNP denotes California
T18126 38027-38028 , denotes ,
T18127 38029-38035 NNP denotes United
T18128 38036-38042 NNPS denotes States
T18129 38042-38043 -RRB- denotes )
T18130 38044-38052 NN denotes software
T18131 38053-38057 IN denotes with
T18132 38058-38063 NNP denotes Fovea
T18133 38064-38067 FW denotes Pro
T18134 38068-38069 -LRB- denotes (
T18135 38069-38077 NNP denotes Reindeer
T18136 38078-38086 NNP denotes Graphics
T18137 38086-38087 , denotes ,
T18138 38088-38097 NNP denotes Asheville
T18139 38097-38098 , denotes ,
T18140 38099-38104 NNP denotes North
T18141 38105-38113 NNP denotes Carolina
T18142 38113-38114 , denotes ,
T18143 38115-38121 NNP denotes United
T18144 38122-38128 NNPS denotes States
T18145 38128-38129 -RRB- denotes )
T18146 38130-38137 NNS denotes plugins
T18147 38137-38138 . denotes .
T18148 38139-38147 NNP denotes Original
T18149 38148-38154 NNS denotes images
T18150 38155-38158 VBP denotes are
T18151 38159-38168 JJ denotes available
T18152 38168-38169 . denotes .
T18304 38171-38180 NNP denotes Histology
T18305 38180-38181 . denotes .
T18306 38182-38190 JJ denotes 18.5-dpc
T18307 38191-38198 NNS denotes embryos
T18308 38199-38203 VBD denotes were
T18309 38204-38217 VBN denotes exsanguinated
T18310 38218-38221 CC denotes and
T18311 38222-38232 JJ denotes peripheral
T18312 38233-38238 NN denotes blood
T18313 38239-38245 NNS denotes smears
T18314 38246-38250 VBD denotes were
T18315 38251-38259 VBN denotes prepared
T18316 38260-38264 IN denotes from
T18317 38265-38269 DT denotes both
T18318 38270-38276 JJ denotes mutant
T18319 38277-38280 CC denotes and
T18320 38281-38283 NNP denotes WT
T18321 38284-38288 NNS denotes mice
T18322 38288-38289 . denotes .
T18323 38290-38293 DT denotes The
T18324 38294-38300 NNS denotes slides
T18325 38301-38305 VBD denotes were
T18326 38306-38320 JJ denotes Wright-stained
T18327 38321-38324 CC denotes and
T18328 38325-38329 VBN denotes read
T18329 38330-38332 IN denotes by
T18330 38333-38336 NNP denotes DAF
T18331 38336-38337 . denotes .
T18332 38338-38341 IN denotes For
T18333 38342-38347 JJ denotes whole
T18334 38348-38353 VBP denotes mount
T18335 38354-38362 NN denotes analysis
T18336 38362-38363 , denotes ,
T18337 38364-38372 JJ denotes 14.5-dpc
T18338 38373-38375 NNP denotes WT
T18339 38376-38379 CC denotes and
T18340 38380-38386 JJ denotes mutant
T18341 38387-38394 NNS denotes embryos
T18342 38394-38395 , denotes ,
T18343 38396-38399 CC denotes and
T18344 38400-38409 JJ denotes postnatal
T18345 38410-38413 NN denotes day
T18346 38414-38418 CD denotes 10.5
T18347 38419-38423 NNS denotes mice
T18348 38424-38428 VBD denotes were
T18349 38429-38434 VBN denotes fixed
T18350 38435-38437 IN denotes in
T18351 38438-38440 CD denotes 10
T18352 38440-38441 NN denotes %
T18353 38442-38450 NN denotes formalin
T18354 38450-38451 , denotes ,
T18355 38452-38469 JJ denotes paraffin-embedded
T18356 38469-38470 , denotes ,
T18357 38471-38480 VBN denotes sectioned
T18358 38481-38483 IN denotes at
T18359 38484-38485 CD denotes 5
T18360 38486-38488 NN denotes μm
T18361 38488-38489 , denotes ,
T18362 38490-38493 CC denotes and
T18363 38494-38501 VBN denotes stained
T18364 38502-38506 IN denotes with
T18365 38507-38518 NN denotes hematoxylin
T18366 38519-38522 CC denotes and
T18367 38523-38528 NN denotes eosin
T18368 38528-38529 . denotes .
T18369 38530-38535 NNP denotes Liver
T18370 38536-38543 NNS denotes samples
T18371 38544-38545 -LRB- denotes (
T18372 38545-38547 IN denotes at
T18373 38548-38552 CD denotes 14.5
T18374 38553-38556 NN denotes dpc
T18375 38557-38560 CC denotes and
T18376 38561-38565 CD denotes 18.5
T18377 38566-38569 NN denotes dpc
T18378 38569-38570 -RRB- denotes )
T18379 38571-38575 VBD denotes were
T18380 38576-38584 VBN denotes prepared
T18381 38585-38587 IN denotes in
T18382 38588-38589 DT denotes a
T18383 38590-38597 JJ denotes similar
T18384 38598-38604 NN denotes manner
T18385 38604-38605 . denotes .
T18386 38606-38612 NNS denotes Images
T18387 38613-38617 VBD denotes were
T18388 38618-38626 VBN denotes obtained
T18389 38627-38631 IN denotes with
T18390 38632-38637 NNP denotes Nikon
T18391 38638-38648 NNP denotes Labophot-2
T18392 38649-38659 NN denotes microscope
T18393 38659-38660 . denotes .
T18394 38661-38671 NNS denotes Objectives
T18395 38672-38676 VBN denotes used
T18396 38677-38681 VBD denotes were
T18397 38682-38683 NNP denotes E
T18398 38684-38688 NNP denotes Plan
T18399 38689-38693 CD denotes 40/0
T18400 38693-38696 CD denotes .65
T18401 38697-38702 CD denotes 160/0
T18402 38702-38705 CD denotes .17
T18403 38706-38711 NNP denotes Nikon
T18404 38712-38713 -LRB- denotes (
T18405 38713-38715 CD denotes 40
T18406 38715-38716 NN denotes ×
T18407 38717-38726 NN denotes objective
T18408 38726-38727 -RRB- denotes )
T18409 38727-38728 , denotes ,
T18410 38729-38730 NNP denotes E
T18411 38731-38735 NNP denotes Plan
T18412 38736-38741 CD denotes 100/1
T18413 38741-38744 CD denotes .25
T18414 38745-38748 NN denotes oil
T18415 38749-38754 CD denotes 160/0
T18416 38754-38757 CD denotes .17
T18417 38758-38763 NNP denotes Nikon
T18418 38764-38765 -LRB- denotes (
T18419 38765-38768 CD denotes 100
T18420 38768-38769 CD denotes ×
T18421 38770-38779 NN denotes objective
T18422 38779-38780 -RRB- denotes )
T18423 38780-38781 . denotes .
T18424 38782-38785 DT denotes The
T18425 38786-38792 NN denotes camera
T18426 38793-38796 VBD denotes was
T18427 38797-38798 DT denotes a
T18428 38799-38804 NNP denotes Nikon
T18429 38805-38812 NNP denotes Coolpix
T18430 38813-38817 CD denotes 4300
T18431 38817-38818 . denotes .
T18432 38819-38827 NNP denotes Original
T18433 38828-38834 NNS denotes images
T18434 38835-38838 VBP denotes are
T18435 38839-38848 JJ denotes available
T18436 38848-38849 . denotes .
T18572 38851-38859 NNP denotes Northern
T18573 38860-38864 NN denotes blot
T18574 38864-38865 . denotes .
T18575 38866-38867 DT denotes A
T18576 38868-38873 NN denotes mouse
T18577 38874-38883 JJ denotes embryonic
T18578 38884-38890 NN denotes tissue
T18579 38891-38899 NNP denotes Northern
T18580 38900-38904 NN denotes blot
T18581 38905-38911 NN denotes filter
T18582 38912-38913 -LRB- denotes (
T18583 38913-38920 NNP denotes Seegene
T18584 38920-38921 , denotes ,
T18585 38922-38931 NNP denotes Rockville
T18586 38931-38932 , denotes ,
T18587 38933-38941 NNP denotes Maryland
T18588 38941-38942 , denotes ,
T18589 38943-38949 NNP denotes United
T18590 38950-38956 NNPS denotes States
T18591 38956-38957 -RRB- denotes )
T18592 38958-38961 VBD denotes was
T18593 38962-38972 VBN denotes hybridized
T18594 38973-38977 IN denotes with
T18595 38978-38979 DT denotes a
T18596 38980-38984 JJ denotes Sox6
T18597 38985-38990 NN denotes probe
T18598 38991-39000 VBN denotes generated
T18599 39001-39003 IN denotes by
T18600 39004-39010 NNP denotes RT-PCR
T18601 39011-39012 -LRB- denotes (
T18602 39012-39023 NNS denotes nucleotides
T18603 39024-39028 CD denotes 1353
T18604 39029-39033 CD denotes 1927
T18605 39033-39034 -RRB- denotes )
T18606 39035-39038 CC denotes and
T18607 39039-39046 VBN denotes labeled
T18608 39047-39051 IN denotes with
T18609 39052-39053 NNP denotes [
T18610 39053-39058 NNP denotes α-32P
T18611 39058-39059 NNP denotes ]
T18612 39059-39063 NNP denotes dCTP
T18613 39063-39064 , denotes ,
T18614 39065-39067 IN denotes by
T18615 39068-39074 JJ denotes random
T18616 39075-39081 NN denotes primer
T18617 39082-39090 VBG denotes labeling
T18618 39091-39092 -LRB- denotes (
T18619 39092-39103 NNP denotes RediprimeII
T18620 39103-39104 : denotes ;
T18621 39105-39113 NNP denotes Amersham
T18622 39114-39125 NNP denotes Biosciences
T18623 39125-39126 , denotes ,
T18624 39127-39142 NNP denotes Buckinghamshire
T18625 39142-39143 , denotes ,
T18626 39144-39151 NNP denotes England
T18627 39151-39152 , denotes ,
T18628 39153-39159 NNP denotes United
T18629 39160-39167 NNP denotes Kingdom
T18630 39167-39168 -RRB- denotes )
T18631 39168-39169 . denotes .
T18632 39170-39173 DT denotes The
T18633 39174-39187 NN denotes hybridization
T18634 39188-39191 VBD denotes was
T18635 39192-39201 VBN denotes performed
T18636 39202-39204 IN denotes in
T18637 39205-39214 NN denotes phosphate
T18638 39215-39223 VBD denotes buffered
T18639 39224-39225 CD denotes 7
T18640 39225-39226 NN denotes %
T18641 39227-39230 NNP denotes SDS
T18642 39231-39244 NN denotes hybridization
T18643 39245-39253 NN denotes solution
T18644 39253-39254 . denotes .
T18645 39255-39260 NNS denotes Blots
T18646 39261-39265 VBD denotes were
T18647 39266-39272 VBN denotes washed
T18648 39273-39277 IN denotes with
T18649 39278-39281 CD denotes 0.2
T18650 39281-39282 CD denotes ×
T18651 39283-39286 NNP denotes SSC
T18652 39286-39287 , denotes ,
T18653 39288-39289 CD denotes 1
T18654 39289-39290 NN denotes %
T18655 39291-39294 NNP denotes SDS
T18656 39295-39297 IN denotes at
T18657 39298-39300 CD denotes 60
T18658 39301-39302 CD denotes °
T18659 39302-39303 NNP denotes C
T18660 39304-39309 RB denotes prior
T18661 39310-39312 TO denotes to
T18662 39313-39321 NN denotes exposure
T18663 39322-39324 TO denotes to
T18664 39325-39330 NN denotes X-ray
T18665 39331-39335 NN denotes film
T18666 39336-39337 -LRB- denotes (
T18667 39337-39342 NNP denotes Kodak
T18668 39342-39343 , denotes ,
T18669 39344-39353 NNP denotes Rochester
T18670 39353-39354 , denotes ,
T18671 39355-39358 NNP denotes New
T18672 39359-39363 NNP denotes York
T18673 39363-39364 , denotes ,
T18674 39365-39371 NNP denotes United
T18675 39372-39378 NNPS denotes States
T18676 39378-39379 -RRB- denotes )
T18677 39380-39382 IN denotes at
T18678 39383-39384 CD denotes −
T18679 39384-39386 CD denotes 80
T18680 39387-39388 CD denotes °
T18681 39388-39389 NNP denotes C
T18682 39390-39393 IN denotes for
T18683 39394-39395 CD denotes 6
T18684 39396-39398 NN denotes d.
T18901 39400-39404 NNP denotes Cell
T18902 39405-39412 NN denotes culture
T18903 39413-39416 CC denotes and
T18904 39417-39429 NN denotes transfection
T18905 39429-39430 . denotes .
T18906 39431-39436 CD denotes GM979
T18907 39437-39442 NNS denotes cells
T18908 39443-39444 -LRB- denotes (
T18909 39444-39451 NNP denotes Coriell
T18910 39452-39456 NNP denotes Cell
T18911 39457-39469 NNPS denotes Repositories
T18912 39469-39470 , denotes ,
T18913 39471-39477 NNP denotes Camden
T18914 39477-39478 , denotes ,
T18915 39479-39482 NNP denotes New
T18916 39483-39489 NNP denotes Jersey
T18917 39489-39490 , denotes ,
T18918 39491-39497 NNP denotes United
T18919 39498-39504 NNPS denotes States
T18920 39504-39505 -RRB- denotes )
T18921 39506-39510 VBD denotes were
T18922 39511-39519 VBN denotes cultured
T18923 39520-39522 IN denotes in
T18924 39523-39526 NNP denotes Ham
T18925 39526-39528 POS denotes 's
T18926 39529-39532 CD denotes F12
T18927 39533-39537 IN denotes with
T18928 39538-39539 CD denotes 2
T18929 39540-39542 NNP denotes mM
T18930 39543-39554 NNP denotes L-glutamine
T18931 39555-39567 VBD denotes supplemented
T18932 39568-39572 IN denotes with
T18933 39573-39589 JJ denotes heat-inactivated
T18934 39590-39592 CD denotes 10
T18935 39592-39593 NN denotes %
T18936 39594-39599 JJ denotes fetal
T18937 39600-39604 NN denotes calf
T18938 39605-39610 NN denotes serum
T18939 39611-39612 -LRB- denotes (
T18940 39612-39621 NNP denotes Ivitrogen
T18941 39621-39622 , denotes ,
T18942 39623-39631 NNP denotes Carlsbad
T18943 39631-39632 , denotes ,
T18944 39633-39643 NNP denotes California
T18945 39643-39644 , denotes ,
T18946 39645-39651 NNP denotes United
T18947 39652-39658 NNPS denotes States
T18948 39658-39659 -RRB- denotes )
T18949 39659-39660 , denotes ,
T18950 39661-39671 NN denotes penicillin
T18951 39672-39673 -LRB- denotes (
T18952 39673-39676 CD denotes 100
T18953 39677-39685 NN denotes units/ml
T18954 39685-39686 -RRB- denotes )
T18955 39686-39687 , denotes ,
T18956 39688-39700 NNP denotes streptomycin
T18957 39701-39704 CD denotes 100
T18958 39705-39707 NN denotes μg
T18959 39707-39708 NN denotes /
T18960 39708-39710 NN denotes ml
T18961 39710-39711 -RRB- denotes )
T18962 39711-39712 , denotes ,
T18963 39713-39716 CC denotes and
T18964 39717-39728 NNP denotes L-glutamine
T18965 39729-39730 -LRB- denotes (
T18966 39730-39731 CD denotes 2
T18967 39732-39734 NNP denotes mM
T18968 39734-39735 -RRB- denotes )
T18969 39735-39736 . denotes .
T18970 39737-39740 NNP denotes MEL
T18971 39741-39746 NNS denotes cells
T18972 39747-39751 VBD denotes were
T18973 39752-39760 VBN denotes cultured
T18974 39761-39763 IN denotes in
T18975 39764-39768 NNP denotes DMEM
T18976 39769-39781 VBD denotes supplemented
T18977 39782-39784 IN denotes as
T18978 39785-39790 IN denotes above
T18979 39791-39792 -LRB- denotes (
T18980 39792-39799 IN denotes without
T18981 39800-39804 NN denotes heat
T18982 39805-39817 VBG denotes inactivating
T18983 39818-39821 DT denotes the
T18984 39822-39827 NN denotes serum
T18985 39827-39828 -RRB- denotes )
T18986 39828-39829 . denotes .
T18987 39830-39835 CD denotes GM979
T18988 39836-39841 NNS denotes cells
T18989 39842-39843 -LRB- denotes (
T18990 39843-39844 CD denotes 4
T18991 39845-39846 CD denotes ×
T18992 39847-39850 CD denotes 105
T18993 39850-39851 -RRB- denotes )
T18994 39852-39854 IN denotes in
T18995 39855-39858 VB denotes log
T18996 39859-39864 NN denotes phase
T18997 39865-39867 IN denotes of
T18998 39868-39874 NN denotes growth
T18999 39875-39879 VBD denotes were
T19000 39880-39891 VBN denotes transfected
T19001 39892-39896 IN denotes with
T19002 39897-39905 NNS denotes plasmids
T19003 39906-39908 IN denotes by
T19004 39909-39916 NNP denotes FuGENE6
T19005 39917-39918 -LRB- denotes (
T19006 39918-39923 NNP denotes Roche
T19007 39923-39924 , denotes ,
T19008 39925-39937 NNP denotes Indianapolis
T19009 39937-39938 , denotes ,
T19010 39939-39946 NNP denotes Indiana
T19011 39946-39947 , denotes ,
T19012 39948-39954 NNP denotes United
T19013 39955-39961 NNPS denotes States
T19014 39961-39962 -RRB- denotes )
T19015 39962-39963 . denotes .
T19016 39964-39969 NNS denotes Cells
T19017 39970-39974 VBD denotes were
T19018 39975-39986 VBN denotes transfected
T19019 39987-39991 IN denotes with
T19020 39992-39994 JJ denotes ɛy
T19021 39995-40003 NN denotes promoter
T19022 40004-40012 NN denotes reporter
T19023 40013-40023 NNS denotes constructs
T19024 40024-40025 -LRB- denotes (
T19025 40025-40028 CD denotes 500
T19026 40029-40031 NN denotes ng
T19027 40031-40032 -RRB- denotes )
T19028 40033-40038 IN denotes along
T19029 40039-40043 IN denotes with
T19030 40044-40050 DT denotes either
T19031 40051-40056 JJ denotes empty
T19032 40057-40063 NN denotes vector
T19033 40064-40066 CC denotes or
T19034 40067-40071 JJ denotes Sox6
T19035 40072-40086 NN denotes overexpression
T19036 40087-40093 NN denotes vector
T19037 40094-40095 -LRB- denotes (
T19038 40095-40099 CD denotes 1000
T19039 40100-40102 NN denotes ng
T19040 40102-40103 -RRB- denotes )
T19041 40103-40104 . denotes .
T19042 40105-40107 IN denotes In
T19043 40108-40114 NNS denotes assays
T19044 40115-40117 IN denotes of
T19045 40118-40124 NN denotes dosage
T19046 40125-40131 NN denotes effect
T19047 40131-40132 , denotes ,
T19048 40133-40135 PRP denotes we
T19049 40136-40140 VBD denotes used
T19050 40141-40144 CD denotes 200
T19051 40145-40147 NN denotes ng
T19052 40147-40148 , denotes ,
T19053 40149-40152 CD denotes 500
T19054 40153-40155 NN denotes ng
T19055 40155-40156 , denotes ,
T19056 40157-40160 CC denotes and
T19057 40161-40165 CD denotes 1000
T19058 40166-40168 NN denotes ng
T19059 40168-40169 -RRB- denotes )
T19060 40169-40170 . denotes .
T19061 40171-40178 JJ denotes pRL-CMV
T19062 40179-40183 JJ denotes 15ng
T19063 40184-40185 -LRB- denotes (
T19064 40185-40192 NNP denotes Promega
T19065 40192-40193 -RRB- denotes )
T19066 40194-40197 VBD denotes was
T19067 40198-40202 VBN denotes used
T19068 40203-40205 IN denotes as
T19069 40206-40207 DT denotes a
T19070 40208-40215 NN denotes control
T19071 40216-40219 IN denotes for
T19072 40220-40232 NN denotes transfection
T19073 40233-40243 NN denotes efficiency
T19074 40243-40244 . denotes .
T19267 40246-40253 NNP denotes Nuclear
T19268 40254-40261 NN denotes protein
T19269 40262-40269 VB denotes extract
T19270 40270-40273 CC denotes and
T19271 40274-40276 IN denotes in
T19272 40277-40282 NN denotes vitro
T19273 40283-40294 NN denotes translation
T19274 40295-40297 IN denotes of
T19275 40298-40302 NNP denotes Sox6
T19276 40302-40303 . denotes .
T19277 40304-40311 NNP denotes Nuclear
T19278 40312-40320 NNS denotes extracts
T19279 40321-40325 VBD denotes were
T19280 40326-40334 VBN denotes prepared
T19281 40335-40339 IN denotes from
T19282 40340-40343 NNP denotes MEL
T19283 40344-40349 NNS denotes cells
T19284 40350-40351 -LRB- denotes (
T19285 40351-40352 CD denotes 2
T19286 40353-40354 CD denotes ×
T19287 40355-40358 CD denotes 107
T19288 40358-40359 -RRB- denotes )
T19289 40360-40365 VBG denotes using
T19290 40366-40367 DT denotes a
T19291 40368-40371 NN denotes kit
T19292 40372-40373 -LRB- denotes (
T19293 40373-40379 JJ denotes Active
T19294 40380-40385 NN denotes Motif
T19295 40385-40386 , denotes ,
T19296 40387-40395 NNP denotes Carlsbad
T19297 40395-40396 , denotes ,
T19298 40397-40407 NNP denotes California
T19299 40407-40408 , denotes ,
T19300 40409-40415 NNP denotes United
T19301 40416-40422 NNPS denotes States
T19302 40422-40423 -RRB- denotes )
T19303 40423-40424 . denotes .
T19304 40425-40428 DT denotes The
T19305 40429-40433 NNP denotes Sox6
T19306 40434-40436 IN denotes in
T19307 40437-40442 NN denotes vitro
T19308 40443-40454 NN denotes translation
T19309 40455-40465 NN denotes expression
T19310 40466-40472 NN denotes vector
T19311 40472-40473 , denotes ,
T19312 40474-40480 VBN denotes tagged
T19313 40481-40485 IN denotes with
T19314 40486-40491 JJ denotes c-Myc
T19315 40492-40495 CC denotes and
T19316 40496-40498 NNP denotes HA
T19317 40498-40499 , denotes ,
T19318 40500-40503 VBD denotes was
T19319 40504-40513 VBN denotes described
T19320 40514-40520 IN denotes before
T19321 40521-40522 NNP denotes [
T19322 40522-40524 CD denotes 15
T19323 40524-40525 NNP denotes ]
T19324 40525-40526 . denotes .
T19325 40527-40530 DT denotes The
T19326 40531-40542 NN denotes translation
T19327 40543-40546 VBD denotes was
T19328 40547-40556 VBN denotes performed
T19329 40557-40559 IN denotes in
T19330 40560-40561 DT denotes a
T19331 40562-40574 NN denotes reticulocyte
T19332 40575-40581 NN denotes lysate
T19333 40582-40587 VBN denotes based
T19334 40588-40590 IN denotes in
T19335 40591-40596 NN denotes vitro
T19336 40597-40610 JJ denotes translational
T19337 40611-40617 NN denotes system
T19338 40618-40619 -LRB- denotes (
T19339 40619-40622 NNP denotes TNT
T19340 40622-40623 CD denotes ®
T19341 40624-40629 NNP denotes Quick
T19342 40630-40637 NNP denotes Coupled
T19343 40638-40663 NNP denotes Transcription/Translation
T19344 40664-40671 NNPS denotes Systems
T19345 40671-40672 , denotes ,
T19346 40673-40680 NNP denotes Promega
T19347 40680-40681 -RRB- denotes )
T19348 40681-40682 . denotes .
T19349 40683-40684 DT denotes A
T19350 40685-40691 NN denotes vector
T19351 40692-40699 IN denotes without
T19352 40700-40703 DT denotes the
T19353 40704-40708 JJ denotes Sox6
T19354 40709-40715 NN denotes coding
T19355 40716-40724 NN denotes sequence
T19356 40725-40728 VBD denotes was
T19357 40729-40733 RB denotes also
T19358 40734-40744 VBN denotes translated
T19359 40745-40747 IN denotes as
T19360 40748-40749 DT denotes a
T19361 40750-40758 JJ denotes negative
T19362 40759-40766 NN denotes control
T19363 40766-40767 . denotes .
T19522 40769-40779 NNS denotes Antibodies
T19523 40779-40780 . denotes .
T19524 40781-40785 JJ denotes Sox6
T19525 40786-40796 NNS denotes antibodies
T19526 40797-40801 VBN denotes used
T19527 40802-40804 IN denotes in
T19528 40805-40809 DT denotes this
T19529 40810-40815 NN denotes study
T19530 40816-40820 VBD denotes were
T19531 40821-40827 RB denotes either
T19532 40828-40834 RB denotes kindly
T19533 40835-40843 VBN denotes provided
T19534 40844-40846 IN denotes by
T19535 40847-40850 NNP denotes Dr.
T19536 40851-40855 NNP denotes Enzo
T19537 40856-40861 NNP denotes Lalli
T19538 40862-40863 -LRB- denotes (
T19539 40863-40873 NNP denotes Université
T19540 40874-40879 NNP denotes Louis
T19541 40880-40887 NNP denotes Pasteur
T19542 40887-40888 , denotes ,
T19543 40889-40895 NNP denotes France
T19544 40896-40897 NNP denotes [
T19545 40897-40898 CD denotes 7
T19546 40898-40899 NNP denotes ]
T19547 40899-40900 -RRB- denotes )
T19548 40901-40903 CC denotes or
T19549 40904-40916 RB denotes commercially
T19550 40917-40925 VBN denotes obtained
T19551 40926-40927 -LRB- denotes (
T19552 40927-40934 NN denotes Catalog
T19553 40935-40937 UH denotes No
T19554 40937-40938 . denotes .
T19555 40939-40947 JJ denotes sc-17332
T19556 40948-40949 NNP denotes X
T19557 40949-40950 , denotes ,
T19558 40951-40956 NNP denotes Santa
T19559 40957-40961 NNP denotes Cruz
T19560 40962-40975 NNP denotes Biotechnology
T19561 40975-40976 , denotes ,
T19562 40977-40982 NNP denotes Santa
T19563 40983-40987 NNP denotes Cruz
T19564 40987-40988 , denotes ,
T19565 40989-40999 NNP denotes California
T19566 40999-41000 , denotes ,
T19567 41001-41007 NNP denotes United
T19568 41008-41014 NNPS denotes States
T19569 41014-41015 -RRB- denotes )
T19570 41015-41016 . denotes .
T19571 41017-41020 DT denotes All
T19572 41021-41025 JJ denotes Sox6
T19573 41026-41036 NNS denotes antibodies
T19574 41037-41046 VBD denotes generated
T19575 41047-41054 JJ denotes similar
T19576 41055-41062 NNS denotes results
T19577 41062-41063 . denotes .
T19578 41064-41069 JJ denotes c-Myc
T19579 41070-41078 NN denotes antibody
T19580 41079-41082 VBD denotes was
T19581 41083-41092 VBN denotes purchased
T19582 41093-41097 IN denotes from
T19583 41098-41108 NNP denotes Invitrogen
T19584 41108-41109 . denotes .
T19585 41110-41116 JJ denotes Normal
T19586 41117-41123 NN denotes rabbit
T19587 41124-41127 NNP denotes IgG
T19588 41128-41136 NN denotes antibody
T19589 41137-41140 VBD denotes was
T19590 41141-41149 VBN denotes obtained
T19591 41150-41154 IN denotes from
T19592 41155-41162 NNP denotes Upstate
T19593 41163-41176 NNP denotes Biotechnology
T19594 41177-41178 -LRB- denotes (
T19595 41178-41182 NNP denotes Lake
T19596 41183-41189 NNP denotes Placid
T19597 41189-41190 , denotes ,
T19598 41191-41194 NNP denotes New
T19599 41195-41199 NNP denotes York
T19600 41199-41200 , denotes ,
T19601 41201-41207 NNP denotes United
T19602 41208-41214 NNPS denotes States
T19603 41214-41215 -RRB- denotes )
T19604 41215-41216 . denotes .
T19985 41218-41222 NNP denotes EMSA
T19986 41222-41223 . denotes .
T19987 41224-41239 JJ denotes Single-stranded
T19988 41240-41253 JJ denotes complementary
T19989 41254-41270 NNS denotes oligonucleotides
T19990 41271-41275 VBD denotes were
T19991 41276-41284 JJ denotes annealed
T19992 41285-41288 CC denotes and
T19993 41289-41300 JJ denotes end-labeled
T19994 41301-41305 IN denotes with
T19995 41306-41307 NNP denotes [
T19996 41307-41312 NNP denotes γ-32P
T19997 41312-41313 NNP denotes ]
T19998 41314-41317 NNP denotes ATP
T19999 41318-41322 IN denotes with
T20000 41323-41325 CD denotes T4
T20001 41326-41340 NN denotes polynucleotide
T20002 41341-41347 NN denotes kinase
T20003 41347-41348 . denotes .
T20004 41349-41353 NNP denotes EMSA
T20005 41354-41357 VBD denotes was
T20006 41358-41367 VBN denotes performed
T20007 41368-41372 IN denotes with
T20008 41373-41374 CD denotes 5
T20009 41375-41377 NN denotes μg
T20010 41378-41380 IN denotes of
T20011 41381-41388 JJ denotes nuclear
T20012 41389-41397 NNS denotes proteins
T20013 41398-41402 IN denotes from
T20014 41403-41406 NNP denotes MEL
T20015 41407-41412 NNS denotes cells
T20016 41413-41415 CC denotes or
T20017 41416-41417 CD denotes 3
T20018 41418-41420 NN denotes μl
T20019 41421-41423 IN denotes of
T20020 41424-41426 IN denotes in
T20021 41427-41443 JJ denotes vitro-translated
T20022 41444-41448 NNS denotes Sox6
T20023 41449-41454 IN denotes along
T20024 41455-41459 IN denotes with
T20025 41460-41463 DT denotes the
T20026 41464-41476 NN denotes reticulocyte
T20027 41477-41483 NN denotes lysate
T20028 41484-41486 IN denotes in
T20029 41487-41494 JJ denotes binding
T20030 41495-41501 NN denotes buffer
T20031 41501-41502 : denotes :
T20032 41503-41506 CD denotes 100
T20033 41507-41509 NNP denotes mM
T20034 41510-41514 NNP denotes NaCl
T20035 41514-41515 , denotes ,
T20036 41516-41518 CD denotes 10
T20037 41518-41519 NN denotes %
T20038 41520-41528 NN denotes glycerol
T20039 41528-41529 , denotes ,
T20040 41530-41533 CD denotes 200
T20041 41534-41536 NN denotes ng
T20042 41536-41537 NN denotes /
T20043 41537-41539 NN denotes μl
T20044 41540-41543 NNP denotes BSA
T20045 41543-41544 , denotes ,
T20046 41545-41547 CD denotes 50
T20047 41548-41550 NN denotes ng
T20048 41550-41551 NN denotes /
T20049 41551-41553 NN denotes μl
T20050 41554-41558 NN denotes poly
T20051 41559-41560 -LRB- denotes (
T20052 41560-41565 JJ denotes dI-dC
T20053 41565-41566 -RRB- denotes )
T20054 41567-41569 CC denotes or
T20055 41570-41574 NN denotes poly
T20056 41575-41576 -LRB- denotes (
T20057 41576-41581 JJ denotes dG-dC
T20058 41581-41582 -RRB- denotes )
T20059 41582-41583 , denotes ,
T20060 41584-41586 CD denotes 10
T20061 41587-41589 NN denotes mM
T20062 41590-41595 NNS denotes HEPES
T20063 41596-41597 -LRB- denotes (
T20064 41597-41599 NN denotes pH
T20065 41600-41601 CD denotes 7
T20066 41601-41602 -RRB- denotes )
T20067 41602-41603 , denotes ,
T20068 41604-41607 CD denotes 0.1
T20069 41608-41610 NNP denotes mM
T20070 41611-41615 NNP denotes EDTA
T20071 41615-41616 , denotes ,
T20072 41617-41621 CD denotes 0.25
T20073 41622-41624 NNP denotes mM
T20074 41625-41628 NNP denotes DTT
T20075 41628-41629 , denotes ,
T20076 41630-41633 CD denotes 0.6
T20077 41634-41636 NNP denotes mM
T20078 41637-41642 NNP denotes MgCl2
T20079 41642-41643 . denotes .
T20080 41644-41647 IN denotes For
T20081 41648-41659 NN denotes competition
T20082 41660-41662 CC denotes or
T20083 41663-41673 NN denotes supershift
T20084 41674-41680 NNS denotes assays
T20085 41680-41681 , denotes ,
T20086 41682-41685 DT denotes the
T20087 41686-41695 VBN denotes indicated
T20088 41696-41706 JJ denotes unlabelled
T20089 41707-41722 NN denotes oligonucleotide
T20090 41723-41733 NN denotes competitor
T20091 41734-41735 -LRB- denotes (
T20092 41735-41743 JJ denotes 200-fold
T20093 41744-41749 NN denotes molar
T20094 41750-41756 NN denotes excess
T20095 41756-41757 -RRB- denotes )
T20096 41758-41760 CC denotes or
T20097 41761-41769 NN denotes antibody
T20098 41770-41771 -LRB- denotes (
T20099 41771-41772 CD denotes 3
T20100 41773-41775 NN denotes μl
T20101 41775-41776 -RRB- denotes )
T20102 41777-41780 VBD denotes was
T20103 41781-41786 VBN denotes added
T20104 41787-41789 CD denotes 30
T20105 41790-41793 NN denotes min
T20106 41794-41796 TO denotes to
T20107 41797-41799 CD denotes 60
T20108 41800-41803 NN denotes min
T20109 41804-41809 RB denotes prior
T20110 41810-41812 TO denotes to
T20111 41813-41821 NN denotes addition
T20112 41822-41824 IN denotes of
T20113 41825-41837 JJ denotes radiolabeled
T20114 41838-41843 NN denotes probe
T20115 41843-41844 . denotes .
T20116 41845-41854 VBG denotes Following
T20117 41855-41863 NN denotes addition
T20118 41864-41866 IN denotes of
T20119 41867-41870 DT denotes the
T20120 41871-41883 JJ denotes radiolabeled
T20121 41884-41889 NN denotes probe
T20122 41889-41890 , denotes ,
T20123 41891-41894 DT denotes the
T20124 41895-41902 NNS denotes samples
T20125 41903-41907 VBD denotes were
T20126 41908-41917 VBN denotes incubated
T20127 41918-41921 IN denotes for
T20128 41922-41924 CD denotes 30
T20129 41925-41928 NN denotes min
T20130 41929-41931 CC denotes or
T20131 41932-41934 CD denotes 60
T20132 41935-41938 NN denotes min
T20133 41939-41941 IN denotes at
T20134 41942-41946 NN denotes room
T20135 41947-41958 NN denotes temperature
T20136 41959-41962 CC denotes and
T20137 41963-41969 VBN denotes loaded
T20138 41970-41972 IN denotes on
T20139 41973-41974 DT denotes a
T20140 41975-41976 CD denotes 4
T20141 41976-41977 NN denotes %
T20142 41978-41980 CC denotes or
T20143 41981-41982 CD denotes 6
T20144 41982-41983 NN denotes %
T20145 41984-41985 -LRB- denotes (
T20146 41985-41988 FW denotes w/v
T20147 41988-41989 -RRB- denotes )
T20148 41990-42004 NN denotes polyacrylamide
T20149 42005-42008 NN denotes gel
T20150 42008-42009 . denotes .
T20151 42010-42025 NNP denotes Electrophoresis
T20152 42026-42029 VBD denotes was
T20153 42030-42039 VBN denotes performed
T20154 42040-42042 IN denotes at
T20155 42043-42044 DT denotes a
T20156 42045-42053 JJ denotes constant
T20157 42054-42056 CD denotes 19
T20158 42057-42061 NN denotes mAmp
T20159 42062-42065 IN denotes for
T20160 42066-42067 CD denotes 4
T20161 42068-42069 CD denotes 8
T20162 42070-42071 NN denotes h
T20163 42072-42074 IN denotes at
T20164 42075-42079 NN denotes room
T20165 42080-42091 NN denotes temperature
T20166 42091-42092 , denotes ,
T20167 42093-42096 CC denotes and
T20168 42097-42100 DT denotes the
T20169 42101-42105 NNS denotes gels
T20170 42106-42110 VBD denotes were
T20171 42111-42116 VBN denotes dried
T20172 42117-42122 RB denotes prior
T20173 42123-42125 TO denotes to
T20174 42126-42141 NN denotes autoradiography
T20175 42141-42142 . denotes .
T20176 42143-42153 NNS denotes Antibodies
T20177 42154-42158 VBD denotes used
T20178 42159-42162 IN denotes for
T20179 42163-42173 NN denotes supershift
T20180 42174-42182 NNS denotes analyses
T20181 42183-42191 VBD denotes included
T20182 42192-42197 NNP denotes c-Myc
T20183 42197-42198 , denotes ,
T20184 42199-42201 NNP denotes HA
T20185 42201-42202 , denotes ,
T20186 42203-42206 CC denotes and
T20187 42207-42211 NNP denotes Sox6
T20188 42212-42222 NNS denotes antibodies
T20189 42223-42224 -LRB- denotes (
T20190 42224-42233 VBN denotes described
T20191 42234-42236 RB denotes as
T20192 42237-42242 IN denotes above
T20193 42242-42243 -RRB- denotes )
T20194 42243-42244 . denotes .
T20195 42245-42248 DT denotes The
T20196 42249-42252 NNP denotes DNA
T20197 42253-42262 NNS denotes sequences
T20198 42263-42265 IN denotes of
T20199 42266-42269 DT denotes the
T20200 42270-42286 NNS denotes oligonucleotides
T20201 42287-42290 VBP denotes are
T20202 42291-42293 IN denotes as
T20203 42294-42301 VBZ denotes follows
T20204 42302-42303 -LRB- denotes (
T20205 42303-42307 RB denotes only
T20206 42308-42315 RB denotes forward
T20207 42316-42322 NNS denotes oligos
T20208 42323-42326 VBP denotes are
T20209 42327-42333 VBN denotes listed
T20210 42333-42334 -RRB- denotes )
T20211 42334-42335 : denotes :
T20212 42336-42339 IN denotes For
T20213 42340-42343 DT denotes the
T20214 42344-42349 JJ denotes 36-bp
T20215 42350-42352 NNP denotes WT
T20216 42353-42358 NN denotes probe
T20217 42358-42359 : denotes :
T20218 42360-42361 CD denotes 5
T20219 42361-42362 CD denotes ′
T20220 42362-42399 NNP denotes AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3
T20221 42399-42400 NNP denotes ′
T20222 42401-42402 -LRB- denotes (
T20223 42402-42409 NNP denotes MHB1556
T20224 42409-42410 -RRB- denotes )
T20225 42410-42411 : denotes ;
T20226 42412-42415 IN denotes for
T20227 42416-42422 JJ denotes mutant
T20228 42423-42428 NN denotes probe
T20229 42429-42430 CD denotes 1
T20230 42431-42432 -LRB- denotes (
T20231 42432-42434 NN denotes M1
T20232 42434-42435 -RRB- denotes )
T20233 42435-42436 : denotes :
T20234 42437-42438 CD denotes 5
T20235 42438-42439 CD denotes ′
T20236 42439-42469 NNP denotes AACAAAGGGTCAGAACATTGTCTGCGAAG3
T20237 42469-42470 NNP denotes ′
T20238 42471-42472 -LRB- denotes (
T20239 42472-42479 NNP denotes MHB1644
T20240 42479-42480 -RRB- denotes )
T20241 42480-42481 : denotes ;
T20242 42482-42485 IN denotes for
T20243 42486-42492 JJ denotes mutant
T20244 42493-42498 NN denotes probe
T20245 42499-42500 CD denotes 2
T20246 42501-42502 -LRB- denotes (
T20247 42502-42504 NN denotes M2
T20248 42504-42505 -RRB- denotes )
T20249 42505-42506 : denotes :
T20250 42507-42508 CD denotes 5
T20251 42508-42509 NN denotes ′
T20252 42509-42546 NNP denotes AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3
T20253 42546-42547 NNP denotes ′
T20254 42548-42549 -LRB- denotes (
T20255 42549-42556 NNP denotes MHB1648
T20256 42556-42557 -RRB- denotes )
T20257 42557-42558 : denotes ;
T20258 42559-42562 IN denotes for
T20259 42563-42569 JJ denotes mutant
T20260 42570-42575 NN denotes probe
T20261 42576-42577 CD denotes 3
T20262 42578-42579 -LRB- denotes (
T20263 42579-42581 NN denotes M3
T20264 42581-42582 -RRB- denotes )
T20265 42582-42583 : denotes :
T20266 42584-42585 CD denotes 5
T20267 42585-42586 NN denotes ′
T20268 42586-42623 NNP denotes AATGCAGtgccAAGGGTCAGAACATTGTCTGCGAAG3
T20269 42623-42624 NNP denotes ′
T20270 42625-42626 -LRB- denotes (
T20271 42626-42633 NNP denotes MHB1650
T20272 42633-42634 -RRB- denotes )
T20273 42634-42635 . denotes .
T20678 42637-42641 NN denotes ChIP
T20679 42642-42647 NN denotes assay
T20680 42647-42648 . denotes .
T20681 42649-42651 IN denotes As
T20682 42652-42661 VBN denotes described
T20683 42662-42664 IN denotes by
T20684 42665-42672 NNP denotes Nouzova
T20685 42673-42674 NNP denotes [
T20686 42674-42676 CD denotes 53
T20687 42676-42677 NNP denotes ]
T20688 42677-42678 , denotes ,
T20689 42679-42681 IN denotes in
T20690 42682-42687 NN denotes brief
T20691 42687-42688 : denotes :
T20692 42689-42694 NNS denotes Cells
T20693 42695-42699 IN denotes from
T20694 42700-42703 NNP denotes MEL
T20695 42704-42709 NNS denotes cells
T20696 42710-42711 -LRB- denotes (
T20697 42711-42712 CD denotes 4
T20698 42713-42714 CD denotes ×
T20699 42715-42718 CD denotes 107
T20700 42718-42719 -RRB- denotes )
T20701 42720-42722 CC denotes or
T20702 42723-42728 JJ denotes fetal
T20703 42729-42734 NN denotes liver
T20704 42735-42740 NNS denotes cells
T20705 42741-42745 IN denotes from
T20706 42746-42751 CD denotes three
T20707 42752-42760 JJ denotes 15.5-dpc
T20708 42761-42763 NNP denotes WT
T20709 42764-42768 NNS denotes mice
T20710 42769-42773 VBD denotes were
T20711 42774-42781 VBN denotes treated
T20712 42782-42786 IN denotes with
T20713 42787-42788 CD denotes 1
T20714 42788-42789 NN denotes %
T20715 42790-42802 NN denotes formaldehyde
T20716 42803-42806 IN denotes for
T20717 42807-42809 CD denotes 10
T20718 42810-42813 NN denotes min
T20719 42814-42816 IN denotes at
T20720 42817-42819 CD denotes 37
T20721 42820-42821 CD denotes °
T20722 42821-42822 NNP denotes C
T20723 42822-42823 , denotes ,
T20724 42824-42830 VBD denotes rinsed
T20725 42831-42833 IN denotes in
T20726 42834-42842 JJ denotes ice-cold
T20727 42843-42844 CD denotes 1
T20728 42844-42845 CD denotes ×
T20729 42846-42851 NNP denotes Hanks
T20730 42851-42852 POS denotes '
T20731 42853-42861 JJ denotes balanced
T20732 42862-42866 NN denotes salt
T20733 42867-42875 NN denotes solution
T20734 42876-42880 IN denotes with
T20735 42881-42884 CD denotes 0.1
T20736 42884-42885 NN denotes %
T20737 42886-42890 NNP denotes EDTA
T20738 42891-42901 VBG denotes containing
T20739 42902-42910 NN denotes protease
T20740 42911-42921 NNS denotes inhibitors
T20741 42921-42922 , denotes ,
T20742 42923-42932 VBN denotes collected
T20743 42933-42935 IN denotes by
T20744 42936-42950 NN denotes centrifugation
T20745 42951-42953 IN denotes at
T20746 42954-42955 CD denotes 4
T20747 42956-42957 CD denotes °
T20748 42957-42958 NNP denotes C
T20749 42958-42959 , denotes ,
T20750 42960-42971 VBD denotes resuspended
T20751 42972-42974 IN denotes in
T20752 42975-42976 DT denotes a
T20753 42977-42980 NNP denotes SDS
T20754 42981-42986 NN denotes lysis
T20755 42987-42993 NN denotes buffer
T20756 42994-43004 VBG denotes containing
T20757 43005-43013 NN denotes protease
T20758 43014-43024 NNS denotes inhibitors
T20759 43024-43025 , denotes ,
T20760 43026-43029 CC denotes and
T20761 43030-43039 VBD denotes incubated
T20762 43040-43042 IN denotes on
T20763 43043-43046 NN denotes ice
T20764 43047-43050 IN denotes for
T20765 43051-43053 CD denotes 10
T20766 43054-43057 NN denotes min
T20767 43057-43058 . denotes .
T20768 43059-43070 JJ denotes DNA-protein
T20769 43071-43080 NNS denotes complexes
T20770 43081-43085 VBD denotes were
T20771 43086-43095 VBN denotes sonicated
T20772 43096-43098 TO denotes to
T20773 43099-43102 CD denotes 200
T20774 43103-43106 CC denotes and
T20775 43107-43110 CD denotes 600
T20776 43111-43113 NN denotes bp
T20777 43113-43114 . denotes .
T20778 43115-43124 NN denotes One-tenth
T20779 43125-43127 IN denotes of
T20780 43128-43131 DT denotes the
T20781 43132-43138 NN denotes sample
T20782 43139-43142 VBD denotes was
T20783 43143-43146 VBN denotes set
T20784 43147-43152 RB denotes aside
T20785 43153-43156 IN denotes for
T20786 43157-43162 NN denotes input
T20787 43163-43170 NN denotes control
T20788 43170-43171 , denotes ,
T20789 43172-43175 CC denotes and
T20790 43176-43179 DT denotes the
T20791 43180-43189 VBG denotes remaining
T20792 43190-43196 NN denotes sample
T20793 43197-43200 VBD denotes was
T20794 43201-43211 VBN denotes precleared
T20795 43212-43216 IN denotes with
T20796 43217-43224 NN denotes protein
T20797 43225-43236 JJ denotes A-Sepharose
T20798 43237-43238 -LRB- denotes (
T20799 43238-43246 NNP denotes Amersham
T20800 43247-43258 NNP denotes Biosciences
T20801 43258-43259 , denotes ,
T20802 43260-43270 NNP denotes Piscataway
T20803 43270-43271 , denotes ,
T20804 43272-43275 NNP denotes New
T20805 43276-43282 NNP denotes Jersey
T20806 43282-43283 , denotes ,
T20807 43284-43290 NNP denotes United
T20808 43291-43297 NNPS denotes States
T20809 43297-43298 -RRB- denotes )
T20810 43298-43299 . denotes .
T20811 43300-43309 VBG denotes Following
T20812 43310-43321 NN denotes preclearing
T20813 43321-43322 , denotes ,
T20814 43323-43326 DT denotes the
T20815 43327-43334 NNS denotes samples
T20816 43335-43339 VBD denotes were
T20817 43340-43345 VBN denotes split
T20818 43346-43350 IN denotes into
T20819 43351-43357 NNS denotes thirds
T20820 43357-43358 : denotes :
T20821 43359-43362 CD denotes one
T20822 43363-43369 NN denotes sample
T20823 43370-43377 VBN denotes treated
T20824 43378-43382 IN denotes with
T20825 43383-43392 JJ denotes anti-Sox6
T20826 43392-43393 , denotes ,
T20827 43394-43395 DT denotes a
T20828 43396-43402 JJ denotes second
T20829 43403-43410 VBN denotes treated
T20830 43411-43415 IN denotes with
T20831 43416-43422 JJ denotes normal
T20832 43423-43429 NN denotes rabbit
T20833 43430-43433 NNP denotes IgG
T20834 43433-43434 , denotes ,
T20835 43435-43438 CC denotes and
T20836 43439-43442 DT denotes the
T20837 43443-43448 JJ denotes third
T20838 43449-43455 NN denotes sample
T20839 43456-43463 IN denotes without
T20840 43464-43466 NNP denotes Ab
T20841 43466-43467 . denotes .
T20842 43468-43471 DT denotes The
T20843 43472-43476 JJ denotes last
T20844 43477-43480 CD denotes two
T20845 43481-43485 VBD denotes were
T20846 43486-43490 VBN denotes used
T20847 43491-43493 IN denotes as
T20848 43494-43502 JJ denotes negative
T20849 43503-43511 NNS denotes controls
T20850 43511-43512 . denotes .
T20851 43513-43516 DT denotes The
T20852 43517-43535 JJ denotes chromatin-antibody
T20853 43536-43545 NNS denotes complexes
T20854 43546-43550 VBD denotes were
T20855 43551-43557 VBN denotes eluted
T20856 43557-43558 , denotes ,
T20857 43559-43562 CC denotes and
T20858 43563-43566 DT denotes the
T20859 43567-43570 NNP denotes DNA
T20860 43571-43578 NN denotes protein
T20861 43579-43590 NNS denotes cross-links
T20862 43591-43595 VBD denotes were
T20863 43596-43604 VBN denotes reversed
T20864 43605-43609 IN denotes with
T20865 43610-43611 CD denotes 5
T20866 43612-43613 NNP denotes M
T20867 43614-43618 NNP denotes NaCl
T20868 43619-43621 IN denotes at
T20869 43622-43624 CD denotes 65
T20870 43625-43626 CD denotes °
T20871 43626-43627 NNP denotes C
T20872 43628-43631 IN denotes for
T20873 43632-43633 CD denotes 4
T20874 43634-43636 NN denotes h.
T20875 43637-43642 NNP denotes Input
T20876 43643-43646 NNP denotes DNA
T20877 43647-43649 CC denotes or
T20878 43650-43668 JJ denotes immunoprecipitated
T20879 43669-43672 NN denotes DNA
T20880 43673-43676 VBD denotes was
T20881 43677-43681 VBN denotes used
T20882 43682-43684 IN denotes as
T20883 43685-43686 DT denotes a
T20884 43687-43695 NN denotes template
T20885 43696-43698 IN denotes in
T20886 43699-43702 DT denotes the
T20887 43703-43706 NNP denotes PCR
T20888 43707-43715 NN denotes reaction
T20889 43715-43716 . denotes .
T20890 43717-43720 NNP denotes PCR
T20891 43721-43734 NN denotes amplification
T20892 43735-43737 IN denotes of
T20893 43738-43741 DT denotes the
T20894 43742-43744 JJ denotes ɛy
T20895 43745-43753 NN denotes promoter
T20896 43754-43757 VBD denotes was
T20897 43758-43767 VBN denotes performed
T20898 43768-43771 CC denotes and
T20899 43772-43779 VBD denotes yielded
T20900 43780-43781 DT denotes a
T20901 43782-43788 JJ denotes 172-bp
T20902 43789-43797 NN denotes amplicon
T20903 43797-43798 , denotes ,
T20904 43799-43812 JJ denotes corresponding
T20905 43813-43815 TO denotes to
T20906 43816-43827 NNS denotes nucleotides
T20907 43828-43829 VBP denotes −
T20908 43829-43831 CD denotes 31
T20909 43832-43834 TO denotes to
T20910 43835-43839 CD denotes +140
T20911 43840-43842 IN denotes of
T20912 43843-43846 DT denotes the
T20913 43847-43849 JJ denotes ɛy
T20914 43850-43858 NN denotes promoter
T20915 43859-43860 -LRB- denotes (
T20916 43860-43867 NNS denotes primers
T20917 43868-43875 NNP denotes MHB1688
T20918 43875-43876 , denotes ,
T20919 43877-43878 CD denotes 5
T20920 43878-43879 NN denotes ′
T20921 43879-43900 CD denotes CGAAGAATAAAAGGCCACCA3
T20922 43900-43901 NN denotes ′
T20923 43901-43902 : denotes ;
T20924 43903-43906 CC denotes and
T20925 43907-43914 NNP denotes MHB1689
T20926 43914-43915 , denotes ,
T20927 43916-43917 CD denotes 5
T20928 43917-43918 NN denotes ′
T20929 43918-43939 NNP denotes GCTTCACCACCAACCTCTTC3
T20930 43939-43940 NNP denotes ′
T20931 43940-43941 -RRB- denotes )
T20932 43941-43942 . denotes .
T20933 43943-43946 NNP denotes PCR
T20934 43947-43950 VBD denotes was
T20935 43951-43960 VBN denotes performed
T20936 43961-43966 IN denotes under
T20937 43967-43970 DT denotes the
T20938 43971-43980 JJ denotes following
T20939 43981-43991 NNS denotes conditions
T20940 43991-43992 : denotes :
T20941 43993-43995 CD denotes 95
T20942 43996-43997 NN denotes °
T20943 43997-43998 NNP denotes C
T20944 43999-44002 IN denotes for
T20945 44003-44005 CD denotes 15
T20946 44006-44009 NN denotes min
T20947 44010-44018 VBN denotes followed
T20948 44019-44021 IN denotes by
T20949 44022-44024 CD denotes 30
T20950 44025-44031 NNS denotes cycles
T20951 44032-44034 IN denotes at
T20952 44035-44037 CD denotes 95
T20953 44038-44039 CD denotes °
T20954 44039-44040 NNP denotes C
T20955 44041-44044 IN denotes for
T20956 44045-44047 CD denotes 30
T20957 44048-44049 PRP denotes s
T20958 44049-44050 , denotes ,
T20959 44051-44053 CD denotes 60
T20960 44054-44055 NN denotes °
T20961 44055-44056 NNP denotes C
T20962 44057-44060 IN denotes for
T20963 44061-44063 CD denotes 30
T20964 44064-44065 PRP denotes s
T20965 44065-44066 , denotes ,
T20966 44067-44070 CC denotes and
T20967 44071-44073 CD denotes 72
T20968 44074-44075 NN denotes °
T20969 44075-44076 NNP denotes C
T20970 44077-44080 IN denotes for
T20971 44081-44083 CD denotes 45
T20972 44084-44085 PRP denotes s
T20973 44085-44086 , denotes ,
T20974 44087-44093 VBG denotes ending
T20975 44094-44098 IN denotes with
T20976 44099-44100 DT denotes a
T20977 44101-44106 JJ denotes final
T20978 44107-44116 NN denotes extension
T20979 44117-44119 IN denotes at
T20980 44120-44122 CD denotes 72
T20981 44123-44124 CD denotes °
T20982 44124-44125 NNP denotes C
T20983 44126-44129 IN denotes for
T20984 44130-44131 CD denotes 5
T20985 44132-44135 NN denotes min
T20986 44135-44136 . denotes .
R10000 T14394 T14393 xcomp bending,cause
R10001 T14395 T14394 prep of,bending
R10002 T14396 T14397 det the,DNA
R10003 T14463 T14461 pobj globin,of
R10004 T14397 T14395 pobj DNA,of
R10005 T14464 T14463 prep in,globin
R10006 T14465 T14467 amod p100H,mice
R10007 T14398 T14394 punct ",",bending
R10008 T14466 T14467 amod mutant,mice
R10009 T14467 T14464 pobj mice,in
R10010 T14468 T14456 ccomp is,shows
R10011 T14469 T14468 acomp due,is
R10012 T14470 T14469 prep to,due
R10013 T14399 T14394 conj facilitating,bending
R10014 T14471 T14470 pobj defects,to
R10015 T14472 T14471 prep in,defects
R10016 T14473 T14475 det the,mechanism
R10017 T14400 T14401 det the,binding
R10018 T14474 T14475 amod silencing,mechanism
R10019 T14475 T14472 pobj mechanism,in
R10020 T14401 T14399 dobj binding,facilitating
R10021 T14476 T14475 prep of,mechanism
R10022 T14477 T14478 amod definitive,erythropoiesis
R10023 T14478 T14476 pobj erythropoiesis,of
R10024 T14402 T14401 prep of,binding
R10025 T14479 T14480 nsubj that,takes
R10026 T14480 T14475 relcl takes,mechanism
R10027 T14481 T14480 dobj place,takes
R10028 T14482 T14480 prep in,takes
R10029 T14403 T14404 amod other,repressors
R10030 T14483 T14484 det the,liver
R10031 T14484 T14482 pobj liver,in
R10032 T14404 T14405 compound repressors,[
R10033 T14485 T14486 punct (,Figure
R10034 T14486 T14480 npadvmod Figure,takes
R10035 T14487 T14486 nummod 5,Figure
R10036 T14488 T14486 punct ),Figure
R10037 T14405 T14402 pobj [,of
R10038 T14489 T14456 punct .,shows
R10039 T14490 T14495 advcl Taken,demonstrate
R10040 T14406 T14407 nummod 40,]
R10041 T14491 T14490 advmod together,Taken
R10042 T14492 T14495 punct ",",demonstrate
R10043 T14493 T14494 det these,data
R10044 T14407 T14405 appos ],[
R10045 T14494 T14495 nsubj data,demonstrate
R10046 T14495 T14495 ROOT demonstrate,demonstrate
R10047 T14408 T14376 punct .,demonstrated
R10048 T14496 T14506 det that,expression
R10049 T14497 T14498 amod Sox6,functions
R10050 T14498 T14503 nsubj functions,silence
R10051 T14409 T14410 amod Sox6,expression
R10052 T14499 T14498 prep in,functions
R10053 T14500 T14501 amod definitive,erythropoiesis
R10054 T14501 T14499 pobj erythropoiesis,in
R10055 T14502 T14503 aux to,silence
R10056 T14410 T14411 nsubj expression,is
R10057 T14503 T14506 nmod silence,expression
R10058 T14504 T14506 nmod ɛy,expression
R10059 T14505 T14506 compound globin,expression
R10060 T14411 T14411 ROOT is,is
R10061 T14506 T14495 dobj expression,demonstrate
R10062 T14507 T14495 punct .,demonstrate
R10063 T14508 T14510 det The,level
R10064 T14509 T14510 compound expression,level
R10065 T14510 T14525 nsubj level,is
R10066 T14412 T14411 acomp temporally,is
R10067 T14511 T14510 prep of,level
R10068 T14512 T14513 amod ɛy,globin
R10069 T14513 T14511 pobj globin,of
R10070 T14413 T14412 cc and,temporally
R10071 T14514 T14513 prep in,globin
R10072 T14515 T14518 amod homozygous,mice
R10073 T14414 T14412 conj spatially,temporally
R10074 T14516 T14518 amod Sox6,mice
R10075 T14517 T14518 amod null,mice
R10076 T14518 T14514 pobj mice,in
R10077 T14415 T14412 conj coincident,temporally
R10078 T14519 T14510 prep at,level
R10079 T14520 T14524 nummod 15.5,dpc
R10080 T14521 T14520 npadvmod dpc,15.5
R10081 T14416 T14411 prep with,is
R10082 T14522 T14520 cc and,15.5
R10083 T14523 T14520 conj 18.5,15.5
R10084 T14417 T14416 pobj definitive,with
R10085 T14524 T14519 pobj dpc,at
R10086 T14525 T14525 ROOT is,is
R10087 T14526 T14527 advmod statistically,equivalent
R10088 T14418 T14417 punct (,definitive
R10089 T14527 T14525 acomp equivalent,is
R10090 T14528 T14527 prep to,equivalent
R10091 T14529 T14530 det the,level
R10092 T14419 T14417 cc but,definitive
R10093 T14530 T14528 pobj level,to
R10094 T14531 T14530 prep of,level
R10095 T14420 T14421 neg not,primitive
R10096 T14532 T14535 amod βmaj,expression
R10097 T14533 T14534 compound /,min
R10098 T14534 T14535 compound min,expression
R10099 T14535 T14531 pobj expression,of
R10100 T14421 T14417 conj primitive,definitive
R10101 T14536 T14530 prep in,level
R10102 T14537 T14538 det the,livers
R10103 T14422 T14411 punct ),is
R10104 T14538 T14536 pobj livers,in
R10105 T14423 T14423 ROOT erythropoiesis,erythropoiesis
R10106 T14539 T14538 prep of,livers
R10107 T14424 T14425 punct (,Figure
R10108 T14540 T14545 amod 15.5-dpc,mice
R10109 T14541 T14540 cc and,15.5-dpc
R10110 T14542 T14540 conj 18.5-dpc,15.5-dpc
R10111 T14425 T14423 parataxis Figure,erythropoiesis
R10112 T14543 T14545 amod homozygous,mice
R10113 T14544 T14545 compound WT,mice
R10114 T14545 T14539 pobj mice,of
R10115 T14546 T14547 punct (,Figure
R10116 T14547 T14538 appos Figure,livers
R10117 T14426 T14425 nummod 6,Figure
R10118 T14548 T14547 nummod 1,Figure
R10119 T14549 T14547 punct ),Figure
R10120 T14550 T14525 punct .,is
R10121 T14427 T14425 punct ),Figure
R10122 T14551 T14552 nsubj This,demonstrates
R10123 T14552 T14552 ROOT demonstrates,demonstrates
R10124 T14553 T14561 mark that,is
R10125 T14554 T14555 amod ectopic,expression
R10126 T14428 T14423 punct ",",erythropoiesis
R10127 T14555 T14561 nsubj expression,is
R10128 T14556 T14555 prep of,expression
R10129 T14557 T14560 det the,gene
R10130 T14429 T14423 cc and,erythropoiesis
R10131 T14558 T14560 amod ɛy,gene
R10132 T14559 T14560 compound globin,gene
R10133 T14430 T14431 nsubj Sox6,represses
R10134 T14431 T14423 conj represses,erythropoiesis
R10135 T14432 T14434 amod ɛy,expression
R10136 T14433 T14434 compound globin,expression
R10137 T14560 T14556 pobj gene,of
R10138 T14561 T14552 ccomp is,demonstrates
R10139 T14562 T14563 advmod quite,robust
R10140 T14434 T14431 dobj expression,represses
R10141 T14563 T14561 acomp robust,is
R10142 T14564 T14563 prep in,robust
R10143 T14435 T14436 preconj both,in
R10144 T14565 T14567 amod homozygous,mice
R10145 T14566 T14567 amod mutant,mice
R10146 T14567 T14564 pobj mice,in
R10147 T14568 T14552 punct .,demonstrates
R10148 T14436 T14434 prep in,expression
R10149 T14569 T14571 det The,levels
R10150 T14570 T14571 compound expression,levels
R10151 T14437 T14436 pobj vivo,in
R10152 T14571 T14583 nsubj levels,are
R10153 T14572 T14571 prep of,levels
R10154 T14573 T14577 nummod two,genes
R10155 T14438 T14439 punct (,Figure
R10156 T14574 T14577 amod other,genes
R10157 T14575 T14577 amod embryonic,genes
R10158 T14576 T14577 compound globin,genes
R10159 T14439 T14434 appos Figure,expression
R10160 T14577 T14572 pobj genes,of
R10161 T14578 T14577 punct (,genes
R10162 T14440 T14439 nummod 1,Figure
R10163 T14579 T14577 appos ζ,genes
R10164 T14580 T14579 cc and,ζ
R10165 T14441 T14439 punct ),Figure
R10166 T14581 T14579 conj βh1,ζ
R10167 T14582 T14577 punct ),genes
R10168 T14442 T14431 cc and,represses
R10169 T14583 T14583 ROOT are,are
R10170 T14584 T14583 advmod also,are
R10171 T14443 T14431 conj in,represses
R10172 T14585 T14583 acomp higher,are
R10173 T14586 T14585 prep in,higher
R10174 T14587 T14588 amod p100H,homozygotes
R10175 T14444 T14446 amod vitro,Figure
R10176 T14588 T14586 pobj homozygotes,in
R10177 T14589 T14583 punct ",",are
R10178 T14590 T14583 prep compared,are
R10179 T14445 T14446 punct (,Figure
R10180 T14591 T14590 prep with,compared
R10181 T14592 T14591 pobj WT,with
R10182 T14593 T14583 punct .,are
R10183 T14446 T14443 pobj Figure,in
R10184 T14594 T14602 prep Like,are
R10185 T14595 T14594 pobj ɛy,Like
R10186 T14596 T14602 punct ",",are
R10187 T14447 T14446 nummod 2,Figure
R10188 T14597 T14602 nsubj levels,are
R10189 T14598 T14597 prep of,levels
R10190 T14448 T14446 punct ),Figure
R10191 T14599 T14598 pobj ζ,of
R10192 T14600 T14597 cc and,levels
R10193 T14601 T14597 conj βh1,levels
R10194 T14449 T14431 punct .,represses
R10195 T14602 T14602 ROOT are,are
R10196 T14603 T14604 advmod dramatically,higher
R10197 T14604 T14602 acomp higher,are
R10198 T14450 T14456 advmod Moreover,shows
R10199 T14605 T14604 prep in,higher
R10200 T14606 T14607 amod mutant,mice
R10201 T14451 T14456 punct ",",shows
R10202 T14607 T14605 pobj mice,in
R10203 T14608 T14602 prep at,are
R10204 T14609 T14610 nummod 15.5,dpc
R10205 T14452 T14456 prep in,shows
R10206 T14610 T14608 pobj dpc,at
R10207 T14611 T14602 punct .,are
R10208 T14612 T14612 ROOT However,However
R10209 T14453 T14454 compound situ,hybridization
R10210 T14613 T14612 pobj ",",However
R10211 T14614 T14613 xcomp unlike,","
R10212 T14454 T14456 nsubj hybridization,shows
R10213 T14615 T14616 amod ɛy,globin
R10214 T14616 T14614 pobj globin,unlike
R10215 T14617 T14616 punct ",",globin
R10216 T14455 T14456 advmod clearly,shows
R10217 T14618 T14616 conj ζ,globin
R10218 T14619 T14618 cc and,ζ
R10219 T14456 T14456 ROOT shows,shows
R10220 T14620 T14621 amod βh1,decline
R10221 T14621 T14618 conj decline,ζ
R10222 T14622 T14621 prep in,decline
R10223 T14457 T14468 mark that,is
R10224 T14623 T14622 pobj expression,in
R10225 T14624 T14621 prep by,decline
R10226 T14625 T14624 pobj day,by
R10227 T14458 T14460 det the,expression
R10228 T14626 T14625 nummod 18.5,day
R10229 T14459 T14460 amod persistent,expression
R10230 T14627 T14627 ROOT dpc,dpc
R10231 T14628 T14629 punct (,Figure
R10232 T14629 T14627 appos Figure,dpc
R10233 T14460 T14468 nsubj expression,is
R10234 T14630 T14629 nummod 1,Figure
R10235 T14631 T14629 punct ),Figure
R10236 T14632 T14627 punct ",",dpc
R10237 T14461 T14460 prep of,expression
R10238 T14633 T14627 acl suggesting,dpc
R10239 T14634 T14637 mark that,regulated
R10240 T14635 T14637 nsubjpass ɛy,regulated
R10241 T14462 T14463 amod ɛy,globin
R10242 T14636 T14637 auxpass is,regulated
R10243 T14637 T14633 ccomp regulated,suggesting
R10244 T14657 T14656 punct (,genes
R10245 T14638 T14637 advmod differently,regulated
R10246 T14658 T14656 cc and,genes
R10247 T14639 T14638 prep than,differently
R10248 T14640 T14639 pobj ζ,than
R10249 T14659 T14660 amod erythrocyte,maturation
R10250 T14641 T14640 cc and,ζ
R10251 T14642 T14640 conj βh1,ζ
R10252 T14643 T14627 punct .,dpc
R10253 T14660 T14656 conj maturation,genes
R10254 T14644 T14645 nsubj It,is
R10255 T14645 T14645 ROOT is,is
R10256 T14646 T14645 acomp possible,is
R10257 T14661 T14652 punct ),effect
R10258 T14647 T14649 mark that,has
R10259 T14648 T14649 nsubj Sox6,has
R10260 T14649 T14645 ccomp has,is
R10261 T14662 T14649 prep in,has
R10262 T14650 T14652 det a,effect
R10263 T14651 T14652 amod general,effect
R10264 T14652 T14649 dobj effect,has
R10265 T14653 T14652 prep on,effect
R10266 T14654 T14656 amod embryonic,genes
R10267 T14655 T14656 compound globin,genes
R10268 T14663 T14662 pobj addition,in
R10269 T14656 T14653 pobj genes,on
R10270 T14664 T14663 prep to,addition
R10271 T14665 T14667 det a,role
R10272 T14666 T14667 amod specific,role
R10273 T14667 T14664 pobj role,to
R10274 T14754 T14755 det the,levels
R10275 T14668 T14667 prep in,role
R10276 T14755 T14761 nsubj levels,were
R10277 T14756 T14755 prep of,levels
R10278 T14757 T14756 pobj ζ,of
R10279 T14669 T14668 pcomp silencing,in
R10280 T14758 T14757 cc and,ζ
R10281 T14759 T14760 nummod βh1,RNA
R10282 T14760 T14757 conj RNA,ζ
R10283 T14670 T14669 dobj ɛy,silencing
R10284 T14761 T14778 ccomp were,elevated
R10285 T14762 T14761 acomp undetectable,were
R10286 T14671 T14645 punct .,is
R10287 T14763 T14764 advmod both,in
R10288 T14764 T14762 prep in,undetectable
R10289 T14672 T14677 mark Although,die
R10290 T14765 T14764 pobj mutant,in
R10291 T14766 T14765 cc and,mutant
R10292 T14767 T14765 conj WT,mutant
R10293 T14673 T14676 amod most,mice
R10294 T14768 T14778 punct ;,elevated
R10295 T14769 T14778 advmod however,elevated
R10296 T14770 T14778 punct ",",elevated
R10297 T14674 T14676 amod p100H,mice
R10298 T14771 T14775 nmod adult,levels
R10299 T14772 T14775 amod β-like,levels
R10300 T14773 T14775 compound globin,levels
R10301 T14675 T14676 amod mutant,mice
R10302 T14774 T14775 compound RNA,levels
R10303 T14775 T14776 nsubj levels,were
R10304 T14676 T14677 nsubj mice,die
R10305 T14677 T14686 advcl die,survive
R10306 T14776 T14778 auxpass were,elevated
R10307 T14678 T14679 advmod just,after
R10308 T14777 T14778 advmod moderately,elevated
R10309 T14778 T14778 ROOT elevated,elevated
R10310 T14779 T14778 prep in,elevated
R10311 T14679 T14677 prep after,die
R10312 T14780 T14782 det the,RNA
R10313 T14781 T14782 amod mutant,RNA
R10314 T14782 T14779 pobj RNA,in
R10315 T14783 T14778 prep compared,elevated
R10316 T14784 T14783 prep with,compared
R10317 T14680 T14681 auxpass being,born
R10318 T14785 T14784 pobj WT,with
R10319 T14786 T14785 punct (,WT
R10320 T14681 T14679 pcomp born,after
R10321 T14787 T14788 amod unpublished,data
R10322 T14788 T14785 appos data,WT
R10323 T14789 T14785 punct ),WT
R10324 T14682 T14686 punct ",",survive
R10325 T14790 T14785 punct ",",WT
R10326 T14791 T14778 conj similar,elevated
R10327 T14683 T14686 det a,survive
R10328 T14792 T14791 prep to,similar
R10329 T14793 T14795 dobj what,observe
R10330 T14794 T14795 nsubj we,observe
R10331 T14684 T14686 amod rare,survive
R10332 T14795 T14792 pcomp observe,to
R10333 T14796 T14795 prep at,observe
R10334 T14797 T14798 nummod 18.5,dpc
R10335 T14685 T14686 nsubj few,survive
R10336 T14798 T14796 pobj dpc,at
R10337 T14799 T14800 punct (,Figure
R10338 T14800 T14792 pobj Figure,to
R10339 T14686 T14686 ROOT survive,survive
R10340 T14801 T14800 nummod 1,Figure
R10341 T14802 T14800 punct ),Figure
R10342 T14803 T14778 punct .,elevated
R10343 T14687 T14686 advmod longer,survive
R10344 T14804 T14805 det These,findings
R10345 T14805 T14806 nsubj findings,suggest
R10346 T14806 T14806 ROOT suggest,suggest
R10347 T14807 T14809 mark that,continues
R10348 T14688 T14686 punct .,survive
R10349 T14808 T14809 nsubj Sox6,continues
R10350 T14809 T14806 ccomp continues,suggest
R10351 T14810 T14811 aux to,function
R10352 T14689 T14692 nsubjpass None,observed
R10353 T14811 T14809 xcomp function,continues
R10354 T14812 T14811 advmod postnatally,function
R10355 T14690 T14692 aux have,observed
R10356 T14813 T14811 prep to,function
R10357 T14814 T14817 nmod silence,expression
R10358 T14815 T14817 nmod ɛy,expression
R10359 T14691 T14692 auxpass been,observed
R10360 T14816 T14817 compound globin,expression
R10361 T14817 T14813 pobj expression,to
R10362 T14818 T14809 cc and,continues
R10363 T14692 T14692 ROOT observed,observed
R10364 T14819 T14809 conj has,continues
R10365 T14820 T14822 det a,function
R10366 T14821 T14822 amod unique,function
R10367 T14822 T14819 dobj function,has
R10368 T14823 T14822 prep in,function
R10369 T14824 T14825 det the,regulation
R10370 T14693 T14694 aux to,live
R10371 T14825 T14823 pobj regulation,in
R10372 T14826 T14825 prep of,regulation
R10373 T14827 T14826 pobj ɛy-globin,of
R10374 T14694 T14692 xcomp live,observed
R10375 T14828 T14806 punct .,suggest
R10376 T14829 T14830 det The,mechanism
R10377 T14830 T14840 nsubj mechanism,remains
R10378 T14695 T14698 amod longer,wk
R10379 T14831 T14834 prep by,regulates
R10380 T14832 T14831 pobj which,by
R10381 T14696 T14698 quantmod than,wk
R10382 T14833 T14834 nsubj Sox6,regulates
R10383 T14834 T14830 relcl regulates,mechanism
R10384 T14697 T14698 nummod 2,wk
R10385 T14835 T14839 det the,genes
R10386 T14836 T14839 amod other,genes
R10387 T14837 T14839 amod embryonic,genes
R10388 T14698 T14694 dobj wk,live
R10389 T14838 T14839 compound globin,genes
R10390 T14839 T14834 dobj genes,regulates
R10391 T14840 T14840 ROOT remains,remains
R10392 T14699 T14694 prep after,live
R10393 T14841 T14843 aux to,elucidated
R10394 T14842 T14843 auxpass be,elucidated
R10395 T14843 T14840 xcomp elucidated,remains
R10396 T14700 T14703 nsubjpass birth,]
R10397 T14844 T14840 punct .,remains
R10398 T14845 T14846 nsubj Sox6,has
R10399 T14846 T14846 ROOT has,has
R10400 T14701 T14703 nmod [,]
R10401 T14847 T14848 amod other,effects
R10402 T14848 T14846 dobj effects,has
R10403 T14849 T14848 prep in,effects
R10404 T14702 T14703 nummod 14,]
R10405 T14850 T14849 pobj erythropoiesis,in
R10406 T14703 T14699 pobj ],after
R10407 T14704 T14692 punct .,observed
R10408 T14705 T14706 nsubj We,examined
R10409 T14851 T14848 punct ",",effects
R10410 T14706 T14706 ROOT examined,examined
R10411 T14852 T14848 prep including,effects
R10412 T14853 T14854 det a,delay
R10413 T14854 T14852 pobj delay,including
R10414 T14707 T14710 det a,sample
R10415 T14708 T14710 amod single,sample
R10416 T14855 T14854 prep in,delay
R10417 T14709 T14710 amod archived,sample
R10418 T14856 T14855 pobj enucleation/maturation,in
R10419 T14857 T14854 prep in,delay
R10420 T14710 T14706 dobj sample,examined
R10421 T14858 T14860 amod p100H,mice
R10422 T14859 T14860 amod mutant,mice
R10423 T14711 T14710 prep of,sample
R10424 T14860 T14857 pobj mice,in
R10425 T14861 T14846 punct .,has
R10426 T14862 T14864 nsubj This,be
R10427 T14712 T14713 compound liver,RNA
R10428 T14863 T14864 aux may,be
R10429 T14713 T14711 pobj RNA,of
R10430 T14864 T14864 ROOT be,be
R10431 T14865 T14866 det the,result
R10432 T14866 T14864 attr result,be
R10433 T14714 T14710 prep from,sample
R10434 T14867 T14866 prep of,result
R10435 T14868 T14869 amod indirect,effects
R10436 T14715 T14717 det a,mouse
R10437 T14869 T14867 pobj effects,of
R10438 T14870 T14869 punct ",",effects
R10439 T14716 T14717 amod mutant,mouse
R10440 T14871 T14872 amod such,as
R10441 T14872 T14869 prep as,effects
R10442 T14873 T14874 compound stress-induced,proliferation
R10443 T14717 T14714 pobj mouse,from
R10444 T14874 T14872 pobj proliferation,as
R10445 T14875 T14874 punct (,proliferation
R10446 T14876 T14874 acl resulting,proliferation
R10447 T14718 T14717 prep on,mouse
R10448 T14877 T14876 prep from,resulting
R10449 T14878 T14879 amod cardiac,defects
R10450 T14879 T14877 pobj defects,from
R10451 T14719 T14720 amod postnatal,day
R10452 T14880 T14874 punct ),proliferation
R10453 T14881 T14874 cc and/or,proliferation
R10454 T14882 T14874 conj anemia,proliferation
R10455 T14720 T14718 pobj day,on
R10456 T14883 T14864 punct .,be
R10457 T14884 T14885 amod Severe,anemia
R10458 T14721 T14720 nummod 13.5,day
R10459 T14885 T14887 nsubj anemia,lead
R10460 T14886 T14887 aux can,lead
R10461 T14887 T14887 ROOT lead,lead
R10462 T14722 T14710 prep for,sample
R10463 T14888 T14887 prep to,lead
R10464 T14889 T14891 amod rapid,release
R10465 T14890 T14891 amod premature,release
R10466 T14891 T14888 pobj release,to
R10467 T14892 T14891 prep of,release
R10468 T14893 T14894 amod red,cells
R10469 T14723 T14725 amod globin,expression
R10470 T14894 T14892 pobj cells,of
R10471 T14895 T14887 punct ",",lead
R10472 T14724 T14725 compound gene,expression
R10473 T14896 T14887 advmod prior,lead
R10474 T14897 T14896 prep to,prior
R10475 T14898 T14900 poss their,maturation
R10476 T14725 T14722 pobj expression,for
R10477 T14899 T14900 amod complete,maturation
R10478 T14900 T14897 pobj maturation,to
R10479 T14901 T14887 punct .,lead
R10480 T14726 T14706 cc and,examined
R10481 T14902 T14910 advmod However,is
R10482 T14903 T14910 punct ",",is
R10483 T14727 T14706 conj detected,examined
R10484 T14904 T14905 det the,hematocrit
R10485 T14905 T14910 nsubj hematocrit,is
R10486 T14906 T14905 prep of,hematocrit
R10487 T14728 T14729 amod high,levels
R10488 T14729 T14727 dobj levels,detected
R10489 T14730 T14729 prep of,levels
R10490 T14907 T14909 amod 18.5-dpc,mice
R10491 T14731 T14732 amod ɛy,globin
R10492 T14908 T14909 amod mutant,mice
R10493 T14909 T14906 pobj mice,of
R10494 T14910 T14910 ROOT is,is
R10495 T14732 T14730 pobj globin,of
R10496 T14911 T14912 advmod only,20
R10497 T14912 T14913 nummod 20,%
R10498 T14733 T14727 prep in,detected
R10499 T14913 T14914 npadvmod %,lower
R10500 T14914 T14910 acomp lower,is
R10501 T14915 T14914 prep than,lower
R10502 T14734 T14736 det this,sample
R10503 T14916 T14915 pobj that,than
R10504 T14917 T14916 prep of,that
R10505 T14918 T14917 pobj WT,of
R10506 T14735 T14736 compound RNA,sample
R10507 T14919 T14918 punct (,WT
R10508 T14920 T14921 amod unpublished,data
R10509 T14921 T14918 appos data,WT
R10510 T14736 T14733 pobj sample,in
R10511 T14922 T14918 punct ),WT
R10512 T14923 T14910 punct ",",is
R10513 T14737 T14727 punct ",",detected
R10514 T14924 T14910 cc and,is
R10515 T14925 T14927 det this,anemia
R10516 T14926 T14927 amod mild,anemia
R10517 T14927 T14928 nsubj anemia,is
R10518 T14928 T14910 conj is,is
R10519 T14738 T14727 prep compared,detected
R10520 T14929 T14928 advmod probably,is
R10521 T14930 T14928 neg not,is
R10522 T14931 T14928 acomp sufficient,is
R10523 T14739 T14738 prep with,compared
R10524 T14932 T14933 aux to,explain
R10525 T14933 T14931 xcomp explain,sufficient
R10526 T14740 T14742 amod undetectable,RNA
R10527 T14741 T14742 compound ɛy,RNA
R10528 T14934 T14935 det the,extent
R10529 T14742 T14739 pobj RNA,with
R10530 T14935 T14933 dobj extent,explain
R10531 T14936 T14935 prep of,extent
R10532 T14743 T14742 prep in,RNA
R10533 T14937 T14939 amod nucleated,cells
R10534 T14938 T14939 amod red,cells
R10535 T14939 T14936 pobj cells,of
R10536 T14744 T14745 compound WT,control
R10537 T14940 T14928 punct .,is
R10538 T14941 T14946 advmod Alternatively,play
R10539 T14745 T14746 compound control,mice
R10540 T14942 T14946 punct ",",play
R10541 T14943 T14946 nsubj Sox6,play
R10542 T14944 T14943 nmod itself,Sox6
R10543 T14746 T14743 pobj mice,in
R10544 T14945 T14946 aux may,play
R10545 T14747 T14706 punct .,examined
R10546 T14748 T14761 prep At,were
R10547 T14749 T14750 det this,point
R10548 T14946 T14946 ROOT play,play
R10549 T14750 T14748 pobj point,At
R10550 T14947 T14948 det a,role
R10551 T14948 T14946 dobj role,play
R10552 T14751 T14750 prep in,point
R10553 T14949 T14948 prep in,role
R10554 T14752 T14751 pobj development,in
R10555 T14753 T14761 punct ",",were
R10556 T15047 T15045 pobj marrow,to
R10557 T14950 T14952 amod red,terminal
R10558 T14951 T14952 compound cell,terminal
R10559 T14952 T14953 compound terminal,differentiation
R10560 T15048 T15047 prep by,marrow
R10561 T14953 T14949 pobj differentiation,in
R10562 T14954 T14946 punct ",",play
R10563 T14955 T14959 mark as,shown
R10564 T15049 T15050 amod postnatal,day
R10565 T14956 T14959 nsubjpass it,shown
R10566 T14957 T14959 aux has,shown
R10567 T14958 T14959 auxpass been,shown
R10568 T14959 T14946 advcl shown,play
R10569 T14960 T14961 aux to,be
R10570 T14961 T14959 xcomp be,shown
R10571 T15050 T15048 pobj day,by
R10572 T14962 T14964 det an,factor
R10573 T14963 T14964 amod important,factor
R10574 T14964 T14961 attr factor,be
R10575 T15051 T15050 nummod 10.5,day
R10576 T14965 T14964 prep in,factor
R10577 T14966 T14967 amod cardiac,[
R10578 T14967 T14969 nmod [,]
R10579 T15052 T15041 punct .,shifted
R10580 T14968 T14969 nummod 15,]
R10581 T14969 T14965 pobj ],in
R10582 T15053 T15055 det The,change
R10583 T14970 T14969 punct ",",]
R10584 T14971 T14972 compound neuronal,[
R10585 T14972 T14974 nmod [,]
R10586 T15054 T15055 amod accompanying,change
R10587 T14973 T14974 nummod 10,]
R10588 T14974 T14969 appos ],]
R10589 T14975 T14974 punct ",",]
R10590 T15055 T15064 nsubj change,permit
R10591 T14976 T14977 compound astrocytic,[
R10592 T14977 T14964 appos [,factor
R10593 T15056 T15055 prep in,change
R10594 T14978 T14979 nummod 11,]
R10595 T14979 T14964 conj ],factor
R10596 T14980 T14979 punct ",",]
R10597 T15057 T15058 det the,microenvironment
R10598 T14981 T14979 cc and,]
R10599 T14982 T14984 compound cartilage,programs
R10600 T15058 T15056 pobj microenvironment,in
R10601 T14983 T14984 compound differentiation,programs
R10602 T14984 T14979 conj programs,]
R10603 T15059 T15058 prep of,microenvironment
R10604 T14985 T14986 compound [,"32,41"
R10605 T14986 T14984 appos "32,41",programs
R10606 T14987 T14988 nummod 44,]
R10607 T14988 T14979 npadvmod ],]
R10608 T15060 T15062 amod red,production
R10609 T14989 T14946 punct .,play
R10610 T14990 T14991 det The,restoration
R10611 T14991 T15006 nsubj restoration,result
R10612 T15061 T15062 compound cell,production
R10613 T14992 T14991 prep of,restoration
R10614 T14993 T14994 amod normal,enucleation
R10615 T14994 T14992 pobj enucleation,of
R10616 T14995 T14994 prep of,enucleation
R10617 T14996 T14997 amod red,cells
R10618 T15062 T15059 pobj production,of
R10619 T14997 T14995 pobj cells,of
R10620 T14998 T14994 prep in,enucleation
R10621 T15063 T15064 aux may,permit
R10622 T14999 T15000 amod Sox6-deficient,mouse
R10623 T15000 T14998 pobj mouse,in
R10624 T15001 T14991 prep by,restoration
R10625 T15002 T15003 amod postnatal,day
R10626 T15064 T15064 ROOT permit,permit
R10627 T15003 T15001 pobj day,by
R10628 T15004 T15003 nummod 10.5,day
R10629 T15065 T15066 amod normal,enucleation
R10630 T15005 T15006 aux may,result
R10631 T15006 T15006 ROOT result,result
R10632 T15007 T15006 prep from,result
R10633 T15066 T15064 dobj enucleation,permit
R10634 T15008 T15009 amod functional,compensation
R10635 T15009 T15007 pobj compensation,from
R10636 T15010 T15009 prep of,compensation
R10637 T15011 T15013 amod other,proteins
R10638 T15067 T15064 punct .,permit
R10639 T15012 T15013 compound Sox,proteins
R10640 T15068 T15079 nsubj Identification,shed
R10641 T15013 T15010 pobj proteins,of
R10642 T15069 T15068 prep of,Identification
R10643 T15014 T15015 punct (,expressed
R10644 T15015 T15006 advcl expressed,result
R10645 T15070 T15073 amod Sox6,genes
R10646 T15016 T15015 prep at,expressed
R10647 T15017 T15019 amod later,stages
R10648 T15018 T15019 amod developmental,stages
R10649 T15071 T15073 amod downstream,genes
R10650 T15019 T15016 pobj stages,at
R10651 T15020 T15006 punct ),result
R10652 T15072 T15073 compound target,genes
R10653 T15021 T15006 punct ",",result
R10654 T15022 T15025 mark since,is
R10655 T15073 T15069 pobj genes,of
R10656 T15023 T15024 amod functional,redundancy
R10657 T15024 T15025 nsubj redundancy,is
R10658 T15025 T15006 advcl is,result
R10659 T15026 T15028 det a,theme
R10660 T15074 T15073 cc and,genes
R10661 T15027 T15028 amod recurring,theme
R10662 T15028 T15025 attr theme,is
R10663 T15075 T15077 poss its,proteins
R10664 T15029 T15028 prep with,theme
R10665 T15030 T15031 compound Sox,proteins
R10666 T15031 T15029 pobj proteins,with
R10667 T15032 T15034 compound [,]
R10668 T15033 T15034 compound "13,45,46",]
R10669 T15034 T15031 appos ],proteins
R10670 T15076 T15077 amod interacting,proteins
R10671 T15035 T15006 punct .,result
R10672 T15036 T15041 advmod Moreover,shifted
R10673 T15077 T15073 conj proteins,genes
R10674 T15037 T15041 punct ",",shifted
R10675 T15038 T15041 nsubj erythropoiesis,shifted
R10676 T15039 T15041 aux has,shifted
R10677 T15078 T15079 aux will,shed
R10678 T15040 T15041 advmod already,shifted
R10679 T15041 T15041 ROOT shifted,shifted
R10680 T15042 T15041 prep from,shifted
R10681 T15079 T15079 ROOT shed,shed
R10682 T15043 T15044 amod fetal,liver
R10683 T15044 T15042 pobj liver,from
R10684 T15045 T15041 prep to,shifted
R10685 T15080 T15079 dobj light,shed
R10686 T15046 T15047 compound bone,marrow
R10687 T15081 T15079 prep on,shed
R10688 T15082 T15083 det the,role
R10689 T15083 T15081 pobj role,on
R10690 T15084 T15083 prep of,role
R10691 T15101 T15098 conj in,in
R10692 T15102 T15103 amod vitro,analyses
R10693 T15085 T15084 pobj Sox6,of
R10694 T15103 T15101 pobj analyses,in
R10695 T15104 T15104 ROOT suggest,suggest
R10696 T15105 T15111 mark that,be
R10697 T15086 T15083 prep in,role
R10698 T15106 T15111 nsubj reactivation,be
R10699 T15107 T15106 prep of,reactivation
R10700 T15087 T15089 amod red,terminal
R10701 T15108 T15109 amod human,ɛ-globin
R10702 T15109 T15107 pobj ɛ-globin,of
R10703 T15088 T15089 compound cell,terminal
R10704 T15110 T15111 aux would,be
R10705 T15111 T15104 ccomp be,suggest
R10706 T15112 T15113 advmod therapeutically,beneficial
R10707 T15089 T15090 compound terminal,differentiation
R10708 T15113 T15111 acomp beneficial,be
R10709 T15114 T15113 prep to,beneficial
R10710 T15115 T15114 pobj adults,to
R10711 T15090 T15086 pobj differentiation,in
R10712 T15116 T15115 prep with,adults
R10713 T15117 T15119 amod sickle,disease
R10714 T15118 T15119 compound cell,disease
R10715 T15091 T15090 cc and,differentiation
R10716 T15119 T15116 pobj disease,with
R10717 T15120 T15122 nmod [,]
R10718 T15121 T15122 nummod 47,]
R10719 T15122 T15115 appos ],adults
R10720 T15123 T15111 punct ",",be
R10721 T15124 T15111 advcl providing,be
R10722 T15092 T15094 det the,process
R10723 T15125 T15126 det a,rationale
R10724 T15126 T15124 dobj rationale,providing
R10725 T15127 T15126 prep for,rationale
R10726 T15128 T15129 amod detailed,investigations
R10727 T15093 T15094 compound enucleation,process
R10728 T15129 T15127 pobj investigations,for
R10729 T15130 T15129 prep into,investigations
R10730 T15131 T15133 det the,basis
R10731 T15094 T15090 conj process,differentiation
R10732 T15132 T15133 amod molecular,basis
R10733 T15133 T15130 pobj basis,into
R10734 T15134 T15133 prep of,basis
R10735 T15095 T15079 punct .,shed
R10736 T15135 T15136 compound ɛ-globin,gene
R10737 T15136 T15137 compound gene,silencing
R10738 T15137 T15134 pobj silencing,of
R10739 T15096 T15104 advmod Recently,suggest
R10740 T15138 T15104 punct .,suggest
R10741 T15139 T15141 det The,study
R10742 T15140 T15141 amod present,study
R10743 T15097 T15104 punct ",",suggest
R10744 T15141 T15142 nsubj study,identifies
R10745 T15142 T15142 ROOT identifies,identifies
R10746 T15098 T15104 prep in,suggest
R10747 T15143 T15145 det a,repressor
R10748 T15144 T15145 compound novel,repressor
R10749 T15099 T15098 pobj vivo,in
R10750 T15145 T15142 dobj repressor,identifies
R10751 T15146 T15145 punct ",",repressor
R10752 T15100 T15098 cc and,in
R10753 T15244 T15244 ROOT proposed,proposed
R10754 T15245 T15247 compound [,]
R10755 T15147 T15145 appos Sox6,repressor
R10756 T15246 T15247 compound "49,50",]
R10757 T15148 T15145 punct ",",repressor
R10758 T15149 T15150 nsubj which,binds
R10759 T15247 T15244 dobj ],proposed
R10760 T15150 T15145 relcl binds,repressor
R10761 T15151 T15150 prep to,binds
R10762 T15248 T15244 punct .,proposed
R10763 T15152 T15155 det the,promoter
R10764 T15153 T15155 amod ɛy,promoter
R10765 T15154 T15155 amod proximal,promoter
R10766 T15155 T15151 pobj promoter,to
R10767 T15156 T15145 punct ",",repressor
R10768 T15157 T15142 advmod potentially,identifies
R10769 T15249 T15276 advmod Thus,reveal
R10770 T15158 T15142 prep as,identifies
R10771 T15159 T15158 pobj part,as
R10772 T15160 T15159 prep of,part
R10773 T15161 T15164 det a,complex
R10774 T15250 T15276 punct ",",reveal
R10775 T15162 T15164 amod larger,complex
R10776 T15163 T15164 compound repression,complex
R10777 T15164 T15160 pobj complex,of
R10778 T15251 T15276 nsubj elucidation,reveal
R10779 T15165 T15142 punct .,identifies
R10780 T15166 T15173 mark Because,are
R10781 T15252 T15251 prep of,elucidation
R10782 T15167 T15168 compound murine,Sox6
R10783 T15168 T15173 nsubj Sox6,are
R10784 T15169 T15168 cc and,Sox6
R10785 T15253 T15256 det the,mechanism
R10786 T15170 T15172 poss its,counterpart
R10787 T15254 T15256 amod Sox6,mechanism
R10788 T15255 T15256 compound repression,mechanism
R10789 T15171 T15172 amod human,counterpart
R10790 T15172 T15168 conj counterpart,Sox6
R10791 T15256 T15252 pobj mechanism,of
R10792 T15173 T15187 advcl are,is
R10793 T15174 T15175 nummod 94,%
R10794 T15175 T15176 npadvmod %,identical
R10795 T15257 T15256 cc and,mechanism
R10796 T15176 T15173 acomp identical,are
R10797 T15177 T15176 prep at,identical
R10798 T15178 T15181 det the,level
R10799 T15258 T15256 conj identification,mechanism
R10800 T15179 T15181 amod amino,level
R10801 T15180 T15181 compound acid,level
R10802 T15259 T15258 prep of,identification
R10803 T15181 T15177 pobj level,at
R10804 T15182 T15184 nmod [,]
R10805 T15260 T15261 amod other,components
R10806 T15183 T15184 nummod 48,]
R10807 T15184 T15181 appos ],level
R10808 T15185 T15187 punct ",",is
R10809 T15186 T15187 nsubj it,is
R10810 T15261 T15259 pobj components,of
R10811 T15187 T15187 ROOT is,is
R10812 T15188 T15187 acomp possible,is
R10813 T15189 T15194 mark that,be
R10814 T15262 T15261 prep of,components
R10815 T15190 T15191 compound human,Sox6
R10816 T15191 T15194 nsubj Sox6,be
R10817 T15192 T15194 aux may,be
R10818 T15193 T15194 advmod also,be
R10819 T15194 T15187 ccomp be,is
R10820 T15263 T15265 det the,complex
R10821 T15195 T15194 acomp important,be
R10822 T15196 T15194 prep in,be
R10823 T15197 T15198 amod human,ɛ
R10824 T15264 T15265 compound Sox6-containing,complex
R10825 T15198 T15199 compound ɛ,globin
R10826 T15199 T15200 compound globin,silencing
R10827 T15200 T15196 pobj silencing,in
R10828 T15265 T15262 pobj complex,of
R10829 T15201 T15187 punct .,is
R10830 T15202 T15203 expl There,is
R10831 T15203 T15203 ROOT is,is
R10832 T15266 T15267 aux may,further
R10833 T15204 T15206 amod significant,homology
R10834 T15267 T15269 advmod further,understanding
R10835 T15205 T15206 compound sequence,homology
R10836 T15206 T15203 attr homology,is
R10837 T15207 T15206 prep between,homology
R10838 T15208 T15214 det the,regions
R10839 T15268 T15269 poss our,understanding
R10840 T15209 T15214 amod human,regions
R10841 T15210 T15209 cc and,human
R10842 T15269 T15256 appos understanding,mechanism
R10843 T15211 T15209 conj mouse,human
R10844 T15212 T15214 compound ɛ,regions
R10845 T15213 T15214 compound promoter,regions
R10846 T15214 T15207 pobj regions,between
R10847 T15270 T15269 prep of,understanding
R10848 T15215 T15203 punct ",",is
R10849 T15216 T15203 cc and,is
R10850 T15271 T15273 compound ɛ,regulation
R10851 T15217 T15219 det the,promoter
R10852 T15218 T15219 amod human,promoter
R10853 T15219 T15220 nsubj promoter,contains
R10854 T15272 T15273 compound globin,regulation
R10855 T15220 T15203 conj contains,is
R10856 T15221 T15222 advmod at,least
R10857 T15222 T15223 advmod least,two
R10858 T15273 T15270 pobj regulation,of
R10859 T15223 T15227 nummod two,sites
R10860 T15224 T15227 amod potential,sites
R10861 T15274 T15269 cc and,understanding
R10862 T15225 T15227 amod Sox6,sites
R10863 T15226 T15227 amod binding,sites
R10864 T15227 T15220 dobj sites,contains
R10865 T15275 T15276 advmod potentially,reveal
R10866 T15228 T15220 punct .,contains
R10867 T15229 T15244 advmod Indeed,proposed
R10868 T15230 T15244 punct ",",proposed
R10869 T15231 T15232 det the,existence
R10870 T15232 T15244 nsubjpass existence,proposed
R10871 T15233 T15232 prep of,existence
R10872 T15276 T15276 ROOT reveal,reveal
R10873 T15234 T15235 det a,silencer
R10874 T15235 T15233 pobj silencer,of
R10875 T15236 T15235 prep of,silencer
R10876 T15237 T15241 det the,gene
R10877 T15277 T15279 amod additional,targets
R10878 T15238 T15239 amod human,ɛ
R10879 T15239 T15241 compound ɛ,gene
R10880 T15278 T15279 amod molecular,targets
R10881 T15240 T15241 compound globin,gene
R10882 T15241 T15236 pobj gene,of
R10883 T15242 T15244 aux has,proposed
R10884 T15279 T15276 dobj targets,reveal
R10885 T15243 T15244 auxpass been,proposed
R10886 T15280 T15279 prep for,targets
R10887 T15281 T15282 det the,treatment
R10888 T15282 T15280 pobj treatment,for
R10889 T15283 T15282 prep of,treatment
R10890 T15284 T15285 compound sickle,cell
R10891 T15285 T15286 compound cell,anemia
R10892 T15286 T15283 pobj anemia,of
R10893 T15287 T15286 cc and,anemia
R10894 T15288 T15289 compound β,thalassemias
R10895 T15289 T15286 conj thalassemias,anemia
R10897 T15290 T15276 punct .,reveal
R11478 T16562 T16563 amod Plasmid,construction
R11479 T16563 T16563 ROOT construction,construction
R11480 T16564 T16563 punct .,construction
R11481 T16565 T16570 det The,plasmid
R11482 T16566 T16567 amod ɛy,promoter
R11483 T16567 T16570 compound promoter,plasmid
R11484 T16568 T16570 compound deletion,plasmid
R11485 T16569 T16570 compound reporter,plasmid
R11486 T16570 T16575 nsubjpass plasmid,generated
R11487 T16571 T16570 punct (,plasmid
R11488 T16572 T16570 appos E-luc,plasmid
R11489 T16573 T16570 punct ),plasmid
R11490 T16574 T16575 auxpass was,generated
R11491 T16575 T16575 ROOT generated,generated
R11492 T16576 T16575 agent by,generated
R11493 T16577 T16578 compound PCR,amplification
R11494 T16578 T16576 pobj amplification,by
R11495 T16579 T16578 prep of,amplification
R11496 T16580 T16583 det the,promoter
R11497 T16581 T16583 amod ɛy,promoter
R11498 T16582 T16583 amod proximal,promoter
R11499 T16583 T16579 pobj promoter,of
R11500 T16584 T16575 punct .,generated
R11501 T16585 T16587 det A,fragment
R11502 T16586 T16587 compound 2.2-kb,fragment
R11503 T16587 T16588 compound fragment,upstream
R11504 T16588 T16599 nsubjpass upstream,used
R11505 T16589 T16588 prep of,upstream
R11506 T16590 T16593 det the,initiation
R11507 T16591 T16593 amod ɛy,initiation
R11508 T16592 T16593 compound globin,initiation
R11509 T16593 T16594 compound initiation,codon
R11510 T16594 T16589 pobj codon,of
R11511 T16595 T16596 punct (,ATG
R11512 T16596 T16594 appos ATG,codon
R11513 T16597 T16594 punct ),codon
R11514 T16598 T16599 auxpass was,used
R11515 T16599 T16599 ROOT used,used
R11516 T16600 T16599 punct ",",used
R11517 T16601 T16605 mark because,shown
R11518 T16602 T16605 nsubjpass it,shown
R11519 T16603 T16605 aux has,shown
R11520 T16604 T16605 auxpass been,shown
R11521 T16605 T16599 advcl shown,used
R11522 T16606 T16615 mark that,located
R11523 T16607 T16608 det all,sequences
R11524 T16608 T16615 nsubjpass sequences,located
R11525 T16609 T16608 acl required,sequences
R11526 T16610 T16609 prep for,required
R11527 T16611 T16612 compound ɛ,gene
R11528 T16612 T16610 pobj gene,for
R11529 T16613 T16612 acl silencing,gene
R11530 T16614 T16615 auxpass are,located
R11531 T16615 T16605 ccomp located,shown
R11532 T16616 T16615 prep within,located
R11533 T16617 T16620 det a,fragment
R11534 T16618 T16620 compound 3.7-kb,fragment
R11535 T16619 T16620 compound EcoRI,fragment
R11536 T16620 T16616 pobj fragment,within
R11537 T16621 T16620 acl containing,fragment
R11538 T16622 T16624 quantmod about,kb
R11539 T16623 T16624 nummod 2,kb
R11540 T16624 T16621 dobj kb,containing
R11541 T16625 T16624 prep of,kb
R11542 T16626 T16625 pobj sequence,of
R11543 T16627 T16621 advmod upstream,containing
R11544 T16628 T16627 prep of,upstream
R11545 T16629 T16634 det the,site
R11546 T16630 T16634 nmod ɛ,site
R11547 T16631 T16634 compound globin,site
R11548 T16632 T16633 compound gene,cap
R11549 T16633 T16634 compound cap,site
R11550 T16634 T16628 pobj site,of
R11551 T16635 T16634 appos [,site
R11552 T16636 T16637 nummod 50,]
R11553 T16637 T16634 appos ],site
R11554 T16638 T16599 punct .,used
R11555 T16639 T16640 compound Nucleotide,numbering
R11556 T16640 T16641 nsubj numbering,is
R11557 T16641 T16641 ROOT is,is
R11558 T16642 T16641 acomp relative,is
R11559 T16643 T16642 prep to,relative
R11560 T16644 T16645 det the,transcription
R11561 T16645 T16646 nsubj transcription,start
R11562 T16646 T16641 conj start,is
R11563 T16647 T16646 dobj site,start
R11564 T16648 T16641 punct .,is
R11565 T16649 T16652 det The,site
R11566 T16650 T16652 amod transcriptional,site
R11567 T16651 T16652 compound start,site
R11568 T16652 T16654 nsubjpass site,based
R11569 T16653 T16654 auxpass is,based
R11570 T16654 T16654 ROOT based,based
R11571 T16655 T16654 prep on,based
R11572 T16656 T16658 det the,cDNA
R11573 T16657 T16658 amod longest,cDNA
R11574 T16658 T16655 pobj cDNA,on
R11575 T16659 T16658 prep in,cDNA
R11576 T16660 T16661 det the,Fantom
R11577 T16661 T16659 pobj Fantom,in
R11578 T16662 T16661 punct (,Fantom
R11579 T16663 T16664 compound Functional,Annotation
R11580 T16664 T16661 appos Annotation,Fantom
R11581 T16665 T16664 prep of,Annotation
R11582 T16666 T16665 pobj Mouse,of
R11583 T16667 T16661 punct ),Fantom
R11584 T16668 T16658 conj database,cDNA
R11585 T16669 T16654 punct .,based
R11586 T16670 T16672 det The,primers
R11587 T16671 T16672 compound PCR,primers
R11588 T16672 T16673 nsubj primers,contained
R11589 T16673 T16673 ROOT contained,contained
R11590 T16674 T16677 nmod XhoI,sites
R11591 T16675 T16674 cc and,XhoI
R11592 T16676 T16674 conj HindIII,XhoI
R11593 T16677 T16673 dobj sites,contained
R11594 T16678 T16680 nsubjpass that,used
R11595 T16679 T16680 auxpass were,used
R11596 T16680 T16677 relcl used,sites
R11597 T16681 T16682 aux to,clone
R11598 T16682 T16680 xcomp clone,used
R11599 T16683 T16686 det the,fragment
R11600 T16684 T16686 amod ɛy,fragment
R11601 T16685 T16686 compound promoter,fragment
R11602 T16686 T16682 dobj fragment,clone
R11603 T16687 T16682 advmod upstream,clone
R11604 T16688 T16687 prep of,upstream
R11605 T16689 T16692 det the,gene
R11606 T16690 T16692 amod firefly,gene
R11607 T16691 T16692 compound luciferase,gene
R11608 T16692 T16688 pobj gene,of
R11609 T16693 T16692 prep in,gene
R11610 T16694 T16695 compound pGL3,Basic
R11611 T16695 T16693 pobj Basic,in
R11612 T16696 T16699 punct (,Madison
R11613 T16697 T16699 nmod Promega,Madison
R11614 T16698 T16697 punct ",",Promega
R11615 T16699 T16692 appos Madison,gene
R11616 T16700 T16699 punct ",",Madison
R11617 T16701 T16699 npadvmod Wisconsin,Madison
R11618 T16702 T16701 punct ",",Wisconsin
R11619 T16703 T16704 compound United,States
R11620 T16704 T16701 appos States,Wisconsin
R11621 T16705 T16699 punct ),Madison
R11622 T16706 T16673 punct .,contained
R11623 T16707 T16710 det A,fragment
R11624 T16708 T16710 amod 2.5-kb,fragment
R11625 T16709 T16710 compound SstI/XhoI,fragment
R11626 T16710 T16724 nsubjpass fragment,inserted
R11627 T16711 T16710 prep of,fragment
R11628 T16712 T16713 quantmod μLCRβ,9.3
R11629 T16713 T16711 pobj 9.3,of
R11630 T16714 T16724 punct (,inserted
R11631 T16715 T16716 compound micro,LCR
R11632 T16716 T16724 nsubjpass LCR,inserted
R11633 T16717 T16720 punct ;,]
R11634 T16718 T16720 compound [,]
R11635 T16719 T16720 nummod 31,]
R11636 T16720 T16716 appos ],LCR
R11637 T16721 T16720 punct ),]
R11638 T16722 T16724 auxpass was,inserted
R11639 T16723 T16724 advmod then,inserted
R11640 T16724 T16724 ROOT inserted,inserted
R11641 T16725 T16724 advmod upstream,inserted
R11642 T16726 T16725 prep of,upstream
R11643 T16727 T16729 det the,promoter
R11644 T16728 T16729 amod ɛy,promoter
R11645 T16729 T16726 pobj promoter,of
R11646 T16730 T16729 prep in,promoter
R11647 T16731 T16735 det the,plasmid
R11648 T16732 T16735 amod above,plasmid
R11649 T16733 T16735 amod pGL3,plasmid
R11650 T16734 T16735 amod Basic,plasmid
R11651 T16735 T16730 pobj plasmid,in
R11652 T16736 T16724 punct ",",inserted
R11653 T16737 T16724 advcl resulting,inserted
R11654 T16738 T16737 prep in,resulting
R11655 T16739 T16740 det a,reporter
R11656 T16740 T16738 pobj reporter,in
R11657 T16741 T16724 punct construct,inserted
R11658 T16742 T16747 prep in,driven
R11659 T16743 T16742 pobj which,in
R11660 T16744 T16745 amod luciferase,expression
R11661 T16745 T16747 nsubjpass expression,driven
R11662 T16746 T16747 auxpass is,driven
R11663 T16747 T16724 advcl driven,inserted
R11664 T16748 T16747 agent by,driven
R11665 T16749 T16751 det the,promoter
R11666 T16750 T16751 amod ɛy,promoter
R11667 T16751 T16748 pobj promoter,by
R11668 T16752 T16724 punct .,inserted
R11669 T16753 T16754 det A,series
R11670 T16754 T16763 nsubjpass series,generated
R11671 T16755 T16754 prep of,series
R11672 T16756 T16757 compound deletion,constructs
R11673 T16757 T16755 pobj constructs,of
R11674 T16758 T16757 prep of,constructs
R11675 T16759 T16761 det the,promoter
R11676 T16760 T16761 amod ɛy,promoter
R11677 T16761 T16758 pobj promoter,of
R11678 T16762 T16763 auxpass were,generated
R11679 T16763 T16763 ROOT generated,generated
R11680 T16764 T16763 advmod similarly,generated
R11681 T16765 T16763 punct .,generated
R11682 T16766 T16767 amod Forward,primers
R11683 T16767 T16772 nsubj primers,include
R11684 T16768 T16767 prep with,primers
R11685 T16769 T16771 det an,site
R11686 T16770 T16771 compound XhoI,site
R11687 T16771 T16768 pobj site,with
R11688 T16772 T16772 ROOT include,include
R11689 T16773 T16772 punct :,include
R11690 T16774 T16772 dobj MHB1457,include
R11691 T16775 T16774 punct ",",MHB1457
R11692 T16776 T16779 nummod 5,′
R11693 T16777 T16778 quantmod ′,CCGCTCGAGTGCTAGGCAAACACTCA3
R11694 T16778 T16779 nummod CCGCTCGAGTGCTAGGCAAACACTCA3,′
R11695 T16779 T16774 appos ′,MHB1457
R11696 T16780 T16779 punct (,′
R11697 T16781 T16779 nmod −,′
R11698 T16782 T16781 pobj 2077,−
R11699 T16783 T16779 prep to,′
R11700 T16784 T16783 pobj −,to
R11701 T16785 T16784 appos 2052,−
R11702 T16786 T16784 punct ),−
R11703 T16787 T16783 punct ;,to
R11704 T16788 T16783 pobj MHB1503,to
R11705 T16789 T16788 punct ",",MHB1503
R11706 T16790 T16791 nummod 5,′
R11707 T16791 T16788 appos ′,MHB1503
R11708 T16792 T16793 nummod CCGCTCGAGTCTCTACACTGTCACTCCCTG3,′
R11709 T16793 T16791 appos ′,′
R11710 T16794 T16795 punct (,−
R11711 T16795 T16793 appos −,′
R11712 T16796 T16795 nummod 634,−
R11713 T16797 T16796 prep to,634
R11714 T16798 T16797 pobj −,to
R11715 T16799 T16798 appos 605,−
R11716 T16800 T16798 punct ),−
R11717 T16801 T16802 punct ;,MHB1505
R11718 T16802 T16793 appos MHB1505,′
R11719 T16803 T16802 punct ",",MHB1505
R11720 T16804 T16805 nummod 5,′
R11721 T16805 T16807 dep ′,′
R11722 T16806 T16807 nummod CCGCTCGAGGGAGCCAAAAAAAGAATGC3,′
R11723 T16807 T16802 appos ′,MHB1505
R11724 T16808 T16809 punct (,−
R11725 T16809 T16816 nmod −,MHB1506
R11726 T16810 T16809 nummod 197,−
R11727 T16811 T16815 quantmod to,;
R11728 T16812 T16811 pobj −,to
R11729 T16813 T16812 appos 169,−
R11730 T16814 T16812 punct ),−
R11731 T16815 T16816 punct ;,MHB1506
R11732 T16816 T16830 nmod MHB1506,MHB1532
R11733 T16817 T16816 punct ",",MHB1506
R11734 T16818 T16819 nummod 5,′
R11735 T16819 T16830 nmod ′,MHB1532
R11736 T16820 T16821 nummod CCGCTCGAGCTGACCAATGGCTTCAAAG3,′
R11737 T16821 T16819 appos ′,′
R11738 T16822 T16823 punct (,−
R11739 T16823 T16821 appos −,′
R11740 T16824 T16823 nummod 85,−
R11741 T16825 T16824 prep to,85
R11742 T16826 T16825 pobj −,to
R11743 T16827 T16826 appos 58,−
R11744 T16828 T16826 punct ),−
R11745 T16829 T16830 punct ;,MHB1532
R11746 T16830 T16807 appos MHB1532,′
R11747 T16831 T16830 punct ",",MHB1532
R11748 T16832 T16833 nummod 5,′
R11749 T16833 T16835 dep ′,′
R11750 T16834 T16835 nummod CCGCTCGAGAATGCAGAACAAAGGGTCAGA3,′
R11751 T16835 T16830 appos ′,MHB1532
R11752 T16836 T16837 punct (,−
R11753 T16837 T16835 appos −,′
R11754 T16838 T16837 nummod 63,−
R11755 T16839 T16838 prep to,63
R11756 T16840 T16839 pobj −,to
R11757 T16841 T16840 appos 34,−
R11758 T16842 T16840 punct ),−
R11759 T16843 T16837 punct ;,−
R11760 T16844 T16837 cc and,−
R11761 T16845 T16835 appos MHB1507,′
R11762 T16846 T16845 punct ",",MHB1507
R11763 T16847 T16848 nummod 5,′
R11764 T16848 T16849 compound ′,CCGCTCGAGGTCTGCGAAGAATAAAAGGC
R11765 T16849 T16851 quantmod CCGCTCGAGGTCTGCGAAGAATAAAAGGC,′
R11766 T16850 T16851 nummod 3,′
R11767 T16851 T16835 appos ′,′
R11768 T16852 T16853 punct (,−
R11769 T16853 T16851 appos −,′
R11770 T16854 T16853 dobj 37,−
R11771 T16855 T16853 prep to,−
R11772 T16856 T16855 pobj −,to
R11773 T16857 T16856 appos 9,−
R11774 T16858 T16856 punct ),−
R11775 T16859 T16772 punct .,include
R11776 T16860 T16862 det All,primers
R11777 T16861 T16862 amod forward,primers
R11778 T16862 T16864 nsubjpass primers,used
R11779 T16863 T16864 auxpass were,used
R11780 T16864 T16864 ROOT used,used
R11781 T16865 T16864 prep in,used
R11782 T16866 T16865 pobj combination,in
R11783 T16867 T16864 prep with,used
R11784 T16868 T16872 det the,site
R11785 T16869 T16870 compound reverse,primer
R11786 T16870 T16872 compound primer,site
R11787 T16871 T16872 compound HindIII,site
R11788 T16872 T16867 pobj site,with
R11789 T16873 T16872 punct :,site
R11790 T16874 T16872 appos MHB1477,site
R11791 T16875 T16874 punct ",",MHB1477
R11792 T16876 T16877 nummod 5,′
R11793 T16877 T16874 appos ′,MHB1477
R11794 T16878 T16879 nummod CGGAAGCTTGGGAGGTTGCTGGTGA3,′
R11795 T16879 T16877 appos ′,′
R11796 T16880 T16881 punct (,+45
R11797 T16881 T16879 appos +45,′
R11798 T16882 T16881 prep to,+45
R11799 T16883 T16882 pobj +20,to
R11800 T16884 T16881 punct ),+45
R11801 T16885 T16864 punct .,used
R11802 T16886 T16890 amod Sox6-pcDNA3,]
R11803 T16887 T16890 nummod .1,]
R11804 T16888 T16890 nmod [,]
R11805 T16889 T16890 nummod 15,]
R11806 T16890 T16892 nsubjpass ],used
R11807 T16891 T16892 auxpass was,used
R11808 T16892 T16892 ROOT used,used
R11809 T16893 T16894 aux to,overexpress
R11810 T16894 T16892 xcomp overexpress,used
R11811 T16895 T16894 dobj Sox6,overexpress
R11812 T16896 T16892 punct .,used
R11813 T16897 T16899 det A,version
R11814 T16898 T16899 amod truncated,version
R11815 T16899 T16904 nsubj version,construct
R11816 T16900 T16899 prep of,version
R11817 T16901 T16903 det the,overexpression
R11818 T16902 T16903 amod Sox6,overexpression
R11819 T16903 T16900 pobj overexpression,of
R11820 T16904 T16904 ROOT construct,construct
R11821 T16905 T16908 punct (,)
R11822 T16906 T16908 nmod Sox6-ΔHMG-pcDNA3,)
R11823 T16907 T16906 nummod .1,Sox6-ΔHMG-pcDNA3
R11824 T16908 T16904 punct ),construct
R11825 T16909 T16910 nsubj that,lacks
R11826 T16910 T16904 ccomp lacks,construct
R11827 T16911 T16913 det the,domain
R11828 T16912 T16913 compound HMG,domain
R11829 T16913 T16915 nsubjpass domain,generated
R11830 T16914 T16915 auxpass was,generated
R11831 T16915 T16910 ccomp generated,lacks
R11832 T16916 T16915 punct ",",generated
R11833 T16917 T16918 mark as,described
R11834 T16918 T16915 advcl described,generated
R11835 T16919 T16918 agent by,described
R11836 T16920 T16919 pobj others,by
R11837 T16921 T16923 nmod [,]
R11838 T16922 T16923 nummod 32,]
R11839 T16923 T16920 appos ],others
R11840 T16924 T16904 punct .,construct
R11841 T16925 T16936 nsubjpass Mutagenesis,done
R11842 T16926 T16925 prep of,Mutagenesis
R11843 T16927 T16928 compound Sox/Sox6,consensus
R11844 T16928 T16930 nmod consensus,sites
R11845 T16929 T16930 amod binding,sites
R11846 T16930 T16926 pobj sites,of
R11847 T16931 T16930 prep of,sites
R11848 T16932 T16934 det the,promoter
R11849 T16933 T16934 amod ɛy,promoter
R11850 T16934 T16931 pobj promoter,of
R11851 T16935 T16936 auxpass were,done
R11852 T16936 T16936 ROOT done,done
R11853 T16937 T16936 agent by,done
R11854 T16938 T16937 pobj PCR,by
R11855 T16939 T16936 punct .,done
R11856 T16940 T16941 amod Forward,primers
R11857 T16941 T16951 nsubj primers,include
R11858 T16942 T16941 acl used,primers
R11859 T16943 T16944 aux to,generate
R11860 T16944 T16942 xcomp generate,used
R11861 T16945 T16950 det these,constructs
R11862 T16946 T16950 amod mutagenized,constructs
R11863 T16947 T16950 compound ɛy,constructs
R11864 T16948 T16949 compound promoter,reporter
R11865 T16949 T16950 compound reporter,constructs
R11866 T16950 T16951 nsubj constructs,include
R11867 T16951 T16951 ROOT include,include
R11868 T16952 T16951 punct :,include
R11869 T16953 T16967 nummod MHB1661,MHB1662
R11870 T16954 T16956 punct ",",′
R11871 T16955 T16956 nummod 5,′
R11872 T16956 T16967 nmod ′,MHB1662
R11873 T16957 T16958 nummod CCGCTCGAGAATGCAGTGCCAAGGGTCAGAACATTGTCTGCGAAG3,′
R11874 T16958 T16956 appos ′,′
R11875 T16959 T16960 punct (,−
R11876 T16960 T16958 appos −,′
R11877 T16961 T16960 nummod 63,−
R11878 T16962 T16961 prep to,63
R11879 T16963 T16962 pobj −,to
R11880 T16964 T16963 appos 19,−
R11881 T16965 T16963 punct ),−
R11882 T16966 T16967 punct ;,MHB1662
R11883 T16967 T16951 dobj MHB1662,include
R11884 T16968 T16967 punct ",",MHB1662
R11885 T16969 T16970 nummod 5,′
R11886 T16970 T16986 nmod ′,CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA
R11887 T16971 T16972 nummod CCGCTCGAGAATGCAGAACAAAGGGTCAGATGAGTGTCTGCGAAGAA3,′
R11888 T16972 T16970 appos ′,′
R11889 T16973 T16974 punct (,−
R11890 T16974 T16972 appos −,′
R11891 T16975 T16974 nummod 63,−
R11892 T16976 T16975 prep to,63
R11893 T16977 T16976 pobj −,to
R11894 T16978 T16977 appos 16,−
R11895 T16979 T16977 punct ),−
R11896 T16980 T16970 punct ;,′
R11897 T16981 T16970 cc and,′
R11898 T16982 T16970 conj MHB1663,′
R11899 T16983 T16982 punct ",",MHB1663
R11900 T16984 T16985 nummod 5,′
R11901 T16985 T16986 compound ′,CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA
R11902 T16986 T16967 conj CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA,MHB1662
R11903 T16987 T16988 nummod 3,′
R11904 T16988 T16986 appos ′,CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA
R11905 T16989 T16990 punct (,−
R11906 T16990 T16988 appos −,′
R11907 T16991 T16990 nummod 63,−
R11908 T16992 T16990 prep to,−
R11909 T16993 T16992 pobj −,to
R11910 T16994 T16993 appos 18,−
R11911 T16995 T16993 punct ),−
R11912 T16996 T16951 punct .,include
R12137 T17438 T17438 ROOT Quantitation,Quantitation
R12138 T17439 T17438 prep of,Quantitation
R12139 T17440 T17441 compound globin,mRNA
R12140 T17441 T17439 pobj mRNA,of
R12141 T17442 T17438 punct .,Quantitation
R12142 T17443 T17444 nsubj RNA,was
R12143 T17444 T17444 ROOT was,was
R12144 T17445 T17446 amod first,reverse
R12145 T17446 T17447 advmod reverse,transcribed
R12146 T17447 T17444 acomp transcribed,was
R12147 T17448 T17447 prep to,transcribed
R12148 T17449 T17448 pobj cDNA,to
R12149 T17450 T17444 punct .,was
R12150 T17451 T17460 nsubjpass Primers,obtained
R12151 T17452 T17451 prep for,Primers
R12152 T17453 T17455 compound cDNA,amplification
R12153 T17454 T17455 compound PCR,amplification
R12154 T17455 T17452 pobj amplification,for
R12155 T17456 T17455 prep of,amplification
R12156 T17457 T17458 compound globin,genes
R12157 T17458 T17456 pobj genes,of
R12158 T17459 T17460 auxpass were,obtained
R12159 T17460 T17460 ROOT obtained,obtained
R12160 T17461 T17460 prep from,obtained
R12161 T17462 T17463 compound Primerbank,[
R12162 T17463 T17461 pobj [,from
R12163 T17464 T17465 nummod 51,]
R12164 T17465 T17463 appos ],[
R12165 T17466 T17460 punct .,obtained
R12166 T17467 T17468 det All,primers
R12167 T17468 T17470 nsubjpass primers,searched
R12168 T17469 T17470 auxpass were,searched
R12169 T17470 T17470 ROOT searched,searched
R12170 T17471 T17470 prep against,searched
R12171 T17472 T17474 det the,database
R12172 T17473 T17474 compound NCBI,database
R12173 T17474 T17471 pobj database,against
R12174 T17475 T17476 aux to,confirm
R12175 T17476 T17470 advcl confirm,searched
R12176 T17477 T17476 dobj specificity,confirm
R12177 T17478 T17470 punct .,searched
R12178 T17479 T17479 ROOT For,For
R12179 T17480 T17481 amod ɛy,globin
R12180 T17481 T17479 pobj globin,For
R12181 T17482 T17481 punct :,globin
R12182 T17483 T17496 nmod MHB1666,′
R12183 T17484 T17483 punct ",",MHB1666
R12184 T17485 T17483 nummod 5,MHB1666
R12185 T17486 T17483 nummod ′,MHB1666
R12186 T17487 T17488 nummod TGGCCTGTGGAGTAAGGTCAA3,′
R12187 T17488 T17488 ROOT ′,′
R12188 T17489 T17483 punct ;,MHB1666
R12189 T17490 T17483 cc and,MHB1666
R12190 T17491 T17483 conj MHB1667,MHB1666
R12191 T17492 T17491 punct ",",MHB1667
R12192 T17493 T17496 nummod 5,′
R12193 T17494 T17496 nummod ′,′
R12194 T17495 T17496 compound GAAGCAGAGGACAAGTTCCCA3,′
R12195 T17496 T17481 appos ′,globin
R12196 T17497 T17479 punct .,For
R12197 T17498 T17498 ROOT For,For
R12198 T17499 T17500 amod ζ,globin
R12199 T17500 T17498 pobj globin,For
R12200 T17501 T17500 punct :,globin
R12201 T17502 T17515 nummod MHB1668,′
R12202 T17503 T17507 punct ",",′
R12203 T17504 T17507 nummod 5,′
R12204 T17505 T17507 nmod ′,′
R12205 T17506 T17507 nummod CTACCCCCAGACGAAGACCTA3,′
R12206 T17507 T17502 meta ′,MHB1668
R12207 T17508 T17502 punct ;,MHB1668
R12208 T17509 T17502 cc and,MHB1668
R12209 T17510 T17515 nmod MHB1669,′
R12210 T17511 T17510 punct ",",MHB1669
R12211 T17512 T17513 nummod 5,′
R12212 T17513 T17515 nmod ′,′
R12213 T17514 T17515 nummod CTTAACCGCATCCCCTACGG3,′
R12214 T17515 T17500 appos ′,globin
R12215 T17516 T17498 punct .,For
R12216 T17517 T17517 ROOT For,For
R12217 T17518 T17519 amod βH1,globin
R12218 T17519 T17517 pobj globin,For
R12219 T17520 T17519 punct :,globin
R12220 T17521 T17534 nmod MHB1672,′
R12221 T17522 T17521 punct ",",MHB1672
R12222 T17523 T17521 nummod 5,MHB1672
R12223 T17524 T17521 nummod ′,MHB1672
R12224 T17525 T17526 nummod TGGACAACCTCAAGGAGACC3,′
R12225 T17526 T17526 ROOT ′,′
R12226 T17527 T17521 punct ;,MHB1672
R12227 T17528 T17521 cc and,MHB1672
R12228 T17529 T17521 conj MHB1673,MHB1672
R12229 T17530 T17529 punct ",",MHB1673
R12230 T17531 T17534 nummod 5,′
R12231 T17532 T17534 nummod ′,′
R12232 T17533 T17534 compound ACCTCTGGGGTGAATTCCTT3,′
R12233 T17534 T17519 appos ′,globin
R12234 T17535 T17517 punct .,For
R12235 T17536 T17536 ROOT For,For
R12236 T17537 T17540 amod βmaj,globin
R12237 T17538 T17540 compound /,globin
R12238 T17539 T17540 compound min,globin
R12239 T17540 T17536 pobj globin,For
R12240 T17541 T17540 punct :,globin
R12241 T17542 T17555 nmod MHB1674,′
R12242 T17543 T17542 punct :,MHB1674
R12243 T17544 T17547 nummod 5,′
R12244 T17545 T17547 nummod ′,′
R12245 T17546 T17547 compound ATGGCCTGAATCACTTGGAC3,′
R12246 T17547 T17542 appos ′,MHB1674
R12247 T17548 T17542 punct ;,MHB1674
R12248 T17549 T17542 cc and,MHB1674
R12249 T17550 T17542 conj MHB1675,MHB1674
R12250 T17551 T17550 punct ",",MHB1675
R12251 T17552 T17555 nummod 5,′
R12252 T17553 T17555 nummod ′,′
R12253 T17554 T17555 compound ACGATCATATTGCCCAGGAG3,′
R12254 T17555 T17540 appos ′,globin
R12255 T17556 T17536 punct .,For
R12256 T17557 T17579 advcl Using,run
R12257 T17558 T17562 det the,kit
R12258 T17559 T17562 nmod SYBR,kit
R12259 T17560 T17562 amod green,kit
R12260 T17561 T17562 compound supermix,kit
R12261 T17562 T17557 dobj kit,Using
R12262 T17563 T17557 prep with,Using
R12263 T17564 T17563 pobj ROX,with
R12264 T17565 T17566 punct (,Bio-Rad
R12265 T17566 T17564 appos Bio-Rad,ROX
R12266 T17567 T17566 punct ",",Bio-Rad
R12267 T17568 T17566 conj Hercules,Bio-Rad
R12268 T17569 T17568 punct ",",Hercules
R12269 T17570 T17568 conj California,Hercules
R12270 T17571 T17570 punct ",",California
R12271 T17572 T17573 compound United,States
R12272 T17573 T17570 conj States,California
R12273 T17574 T17570 punct ),California
R12274 T17575 T17579 punct ",",run
R12275 T17576 T17577 compound PCR,amplification
R12276 T17577 T17579 nsubjpass amplification,run
R12277 T17578 T17579 auxpass was,run
R12278 T17579 T17579 ROOT run,run
R12279 T17580 T17579 prep on,run
R12280 T17581 T17585 det an,Biosystems
R12281 T17582 T17585 nmod ABI7000,Biosystems
R12282 T17583 T17585 punct (,Biosystems
R12283 T17584 T17585 compound Applied,Biosystems
R12284 T17585 T17580 pobj Biosystems,on
R12285 T17586 T17585 punct ",",Biosystems
R12286 T17587 T17588 compound Foster,City
R12287 T17588 T17585 conj City,Biosystems
R12288 T17589 T17588 punct ",",City
R12289 T17590 T17588 appos California,City
R12290 T17591 T17590 punct ",",California
R12291 T17592 T17593 compound United,States
R12292 T17593 T17590 appos States,California
R12293 T17594 T17588 punct ),City
R12294 T17595 T17585 prep at,Biosystems
R12295 T17596 T17597 det the,University
R12296 T17597 T17601 nmod University,facility
R12297 T17598 T17597 prep of,University
R12298 T17599 T17598 pobj Arizona,of
R12299 T17600 T17601 amod core,facility
R12300 T17601 T17595 pobj facility,at
R12301 T17602 T17579 punct .,run
R12302 T17603 T17604 det All,PCR
R12303 T17604 T17606 nsubjpass PCR,performed
R12304 T17605 T17606 auxpass was,performed
R12305 T17606 T17606 ROOT performed,performed
R12306 T17607 T17606 prep in,performed
R12307 T17608 T17610 det a,reaction
R12308 T17609 T17610 amod 25-μl,reaction
R12309 T17610 T17607 pobj reaction,in
R12310 T17611 T17610 prep with,reaction
R12311 T17612 T17613 nummod 12.5,μl
R12312 T17613 T17611 pobj μl,with
R12313 T17614 T17616 nmod SYBR,supermix
R12314 T17615 T17616 amod green,supermix
R12315 T17616 T17613 appos supermix,μl
R12316 T17617 T17606 punct .,performed
R12317 T17618 T17619 compound GAPDH,mRNA
R12318 T17619 T17620 compound mRNA,levels
R12319 T17620 T17622 nsubjpass levels,used
R12320 T17621 T17622 auxpass were,used
R12321 T17622 T17622 ROOT used,used
R12322 T17623 T17622 prep as,used
R12323 T17624 T17623 pobj control,as
R12324 T17625 T17624 prep for,control
R12325 T17626 T17627 compound input,RNA
R12326 T17627 T17625 pobj RNA,for
R12327 T17628 T17622 punct .,used
R12328 T17629 T17631 compound Standard,analyses
R12329 T17630 T17631 compound curve,analyses
R12330 T17631 T17633 nsubjpass analyses,performed
R12331 T17632 T17633 auxpass were,performed
R12332 T17633 T17633 ROOT performed,performed
R12333 T17634 T17635 aux to,test
R12334 T17635 T17633 xcomp test,performed
R12335 T17636 T17637 det the,efficiency
R12336 T17637 T17635 dobj efficiency,test
R12337 T17638 T17637 prep of,efficiency
R12338 T17639 T17640 det the,amplifications
R12339 T17640 T17638 pobj amplifications,of
R12340 T17641 T17633 punct .,performed
R12341 T17642 T17644 nsubjpass Triplicates,done
R12342 T17643 T17644 auxpass were,done
R12343 T17644 T17644 ROOT done,done
R12344 T17645 T17644 prep for,done
R12345 T17646 T17648 det each,reaction
R12346 T17647 T17648 compound PCR,reaction
R12347 T17648 T17645 pobj reaction,for
R12348 T17649 T17644 punct .,done
R12349 T17650 T17652 amod Relative,values
R12350 T17651 T17652 amod quantitative,values
R12351 T17652 T17654 nsubjpass values,calculated
R12352 T17653 T17654 auxpass were,calculated
R12353 T17654 T17654 ROOT calculated,calculated
R12354 T17655 T17654 prep in,calculated
R12355 T17656 T17661 det the,Software
R12356 T17657 T17658 compound ABI,Prism
R12357 T17658 T17661 nmod Prism,Software
R12358 T17659 T17661 nummod 7000,Software
R12359 T17660 T17661 compound SDS,Software
R12360 T17661 T17655 pobj Software,in
R12361 T17662 T17664 punct (,Biosystems
R12362 T17663 T17664 compound Applied,Biosystems
R12363 T17664 T17661 appos Biosystems,Software
R12364 T17665 T17664 punct ),Biosystems
R12365 T17666 T17654 cc and,calculated
R12366 T17667 T17654 conj normalized,calculated
R12367 T17668 T17667 prep to,normalized
R12368 T17669 T17668 pobj GAPDH,to
R12369 T17670 T17667 prep in,normalized
R12370 T17671 T17672 compound Microsoft,Excel
R12371 T17672 T17670 pobj Excel,in
R12372 T17673 T17674 punct (,Redmond
R12373 T17674 T17672 appos Redmond,Excel
R12374 T17675 T17674 punct ",",Redmond
R12375 T17676 T17674 conj Washington,Redmond
R12376 T17677 T17676 punct ",",Washington
R12377 T17678 T17679 compound United,States
R12378 T17679 T17674 appos States,Redmond
R12379 T17680 T17674 punct ),Redmond
R12380 T17681 T17654 punct .,calculated
R12562 T17961 T17961 ROOT In,In
R12563 T17962 T17963 compound situ,hybridization
R12564 T17963 T17961 pobj hybridization,In
R12565 T17964 T17963 punct .,hybridization
R12566 T17965 T17966 compound Antisense,probes
R12567 T17966 T17968 nsubjpass probes,designed
R12568 T17967 T17968 auxpass were,designed
R12569 T17968 T17968 ROOT designed,designed
R12570 T17969 T17970 aux to,murine
R12571 T17970 T17968 xcomp murine,designed
R12572 T17971 T17973 amod ɛy,nucleotides
R12573 T17972 T17973 compound globin,nucleotides
R12574 T17973 T17970 dobj nucleotides,murine
R12575 T17974 T17970 npadvmod 509,murine
R12576 T17975 T17970 meta 584,murine
R12577 T17976 T17968 punct ;,designed
R12578 T17977 T17968 conj βmaj,designed
R12579 T17978 T17979 compound globin,nucleotides
R12580 T17979 T17977 dobj nucleotides,βmaj
R12581 T17980 T17979 nummod 458,nucleotides
R12582 T17981 T17979 dep 549,nucleotides
R12583 T17982 T17979 punct ;,nucleotides
R12584 T17983 T17979 cc and,nucleotides
R12585 T17984 T17986 nmod mouse,nucleotides
R12586 T17985 T17986 compound Sox6,nucleotides
R12587 T17986 T17979 conj nucleotides,nucleotides
R12588 T17987 T17979 dep 1353,nucleotides
R12589 T17988 T17979 appos 1927,nucleotides
R12590 T17989 T17977 punct .,βmaj
R12591 T17990 T17992 nsubjpass Embryos,fixed
R12592 T17991 T17992 auxpass were,fixed
R12593 T17992 T17992 ROOT fixed,fixed
R12594 T17993 T17992 advmod overnight,fixed
R12595 T17994 T17992 agent by,fixed
R12596 T17995 T17994 pobj immersion,by
R12597 T17996 T17992 prep in,fixed
R12598 T17997 T17998 nummod 4,%
R12599 T17998 T17999 compound %,paraformaldehyde
R12600 T17999 T17996 pobj paraformaldehyde,in
R12601 T18000 T17992 punct ",",fixed
R12602 T18001 T17992 conj embedded,fixed
R12603 T18002 T18001 prep in,embedded
R12604 T18003 T18002 pobj paraffin,in
R12605 T18004 T17992 punct ",",fixed
R12606 T18005 T17992 conj sectioned,fixed
R12607 T18006 T18005 prep at,sectioned
R12608 T18007 T18008 nummod 5,μm
R12609 T18008 T18006 pobj μm,at
R12610 T18009 T17992 punct ",",fixed
R12611 T18010 T17992 cc and,fixed
R12612 T18011 T17992 conj adhered,fixed
R12613 T18012 T18013 aux to,charge
R12614 T18013 T18011 xcomp charge,adhered
R12615 T18014 T18015 amod modified,slides
R12616 T18015 T18013 dobj slides,charge
R12617 T18016 T18017 punct (,VWR
R12618 T18017 T18015 appos VWR,slides
R12619 T18018 T18017 punct ",",VWR
R12620 T18019 T18020 compound West,Chester
R12621 T18020 T18017 conj Chester,VWR
R12622 T18021 T18020 punct ",",Chester
R12623 T18022 T18020 conj Pennsylvania,Chester
R12624 T18023 T18022 punct ",",Pennsylvania
R12625 T18024 T18025 compound United,States
R12626 T18025 T18022 conj States,Pennsylvania
R12627 T18026 T18015 punct ),slides
R12628 T18027 T17992 punct .,fixed
R12629 T18028 T18030 nsubjpass Slides,processed
R12630 T18029 T18030 auxpass were,processed
R12631 T18030 T18030 ROOT processed,processed
R12632 T18031 T18030 prep for,processed
R12633 T18032 T18030 prep in,processed
R12634 T18033 T18034 compound situ,hybridization
R12635 T18034 T18032 pobj hybridization,in
R12636 T18035 T18036 mark as,described
R12637 T18036 T18030 advcl described,processed
R12638 T18037 T18039 nmod [,]
R12639 T18038 T18039 nummod 52,]
R12640 T18039 T18036 dobj ],described
R12641 T18040 T18036 advcl using,described
R12642 T18041 T18040 prep in,using
R12643 T18042 T18041 pobj vitro,in
R12644 T18043 T18045 amod transcribed,probes
R12645 T18044 T18045 compound RNA,probes
R12646 T18045 T18040 dobj probes,using
R12647 T18046 T18045 acl labeled,probes
R12648 T18047 T18046 prep with,labeled
R12649 T18048 T18047 pobj 33P,with
R12650 T18049 T18030 punct .,processed
R12651 T18050 T18053 nmod Darkfield,images
R12652 T18051 T18050 cc and,Darkfield
R12653 T18052 T18050 conj brightfield,Darkfield
R12654 T18053 T18055 nsubjpass images,obtained
R12655 T18054 T18055 auxpass were,obtained
R12656 T18055 T18055 ROOT obtained,obtained
R12657 T18056 T18055 prep with,obtained
R12658 T18057 T18060 det a,microscope
R12659 T18058 T18060 compound Nikon,microscope
R12660 T18059 T18060 compound Optiphot,microscope
R12661 T18060 T18056 pobj microscope,with
R12662 T18061 T18062 punct (,Nikon
R12663 T18062 T18076 nmod Nikon,camera
R12664 T18063 T18062 punct ",",Nikon
R12665 T18064 T18062 conj Melville,Nikon
R12666 T18065 T18064 punct ",",Melville
R12667 T18066 T18067 compound New,York
R12668 T18067 T18064 conj York,Melville
R12669 T18068 T18067 punct ",",York
R12670 T18069 T18070 compound United,States
R12671 T18070 T18067 conj States,York
R12672 T18071 T18070 punct ),States
R12673 T18072 T18070 cc and,States
R12674 T18073 T18076 nmod SPOT,camera
R12675 T18074 T18076 amod RT-Slider,camera
R12676 T18075 T18076 amod digital,camera
R12677 T18076 T18060 appos camera,microscope
R12678 T18077 T18079 punct (,Instruments
R12679 T18078 T18079 compound Diagnostic,Instruments
R12680 T18079 T18076 appos Instruments,camera
R12681 T18080 T18079 punct ",",Instruments
R12682 T18081 T18082 compound Sterling,Heights
R12683 T18082 T18079 conj Heights,Instruments
R12684 T18083 T18082 punct ",",Heights
R12685 T18084 T18082 conj Michigan,Heights
R12686 T18085 T18084 punct ",",Michigan
R12687 T18086 T18087 compound United,States
R12688 T18087 T18084 conj States,Michigan
R12689 T18088 T18079 punct ),Instruments
R12690 T18089 T18055 punct .,obtained
R12691 T18090 T18092 nsubj Objectives,were
R12692 T18091 T18090 acl used,Objectives
R12693 T18092 T18092 ROOT were,were
R12694 T18093 T18094 nummod 1,×
R12695 T18094 T18092 attr ×,were
R12696 T18095 T18098 punct (,0.04
R12697 T18096 T18098 dep NA,0.04
R12698 T18097 T18098 punct =,0.04
R12699 T18098 T18094 parataxis 0.04,×
R12700 T18099 T18098 punct ),0.04
R12701 T18100 T18098 cc and,0.04
R12702 T18101 T18102 nummod 10,×
R12703 T18102 T18098 conj ×,0.04
R12704 T18103 T18102 punct (,×
R12705 T18104 T18107 nmod NA,)
R12706 T18105 T18106 punct =,0.5
R12707 T18106 T18104 nummod 0.5,NA
R12708 T18107 T18102 punct ),×
R12709 T18108 T18092 punct .,were
R12710 T18109 T18111 nsubjpass Images,processed
R12711 T18110 T18111 auxpass were,processed
R12712 T18111 T18111 ROOT processed,processed
R12713 T18112 T18111 punct ",",processed
R12714 T18113 T18111 conj pseudocolored,processed
R12715 T18114 T18113 punct ",",pseudocolored
R12716 T18115 T18113 cc and,pseudocolored
R12717 T18116 T18113 conj combined,pseudocolored
R12718 T18117 T18116 advcl using,combined
R12719 T18118 T18117 dobj Photoshop,using
R12720 T18119 T18120 punct (,Adobe
R12721 T18120 T18118 appos Adobe,Photoshop
R12722 T18121 T18120 punct ",",Adobe
R12723 T18122 T18123 compound San,Jose
R12724 T18123 T18120 npadvmod Jose,Adobe
R12725 T18124 T18123 punct ",",Jose
R12726 T18125 T18123 conj California,Jose
R12727 T18126 T18125 punct ",",California
R12728 T18127 T18128 compound United,States
R12729 T18128 T18125 appos States,California
R12730 T18129 T18125 punct ),California
R12731 T18130 T18118 conj software,Photoshop
R12732 T18131 T18117 prep with,using
R12733 T18132 T18136 nmod Fovea,Graphics
R12734 T18133 T18136 nmod Pro,Graphics
R12735 T18134 T18136 punct (,Graphics
R12736 T18135 T18136 compound Reindeer,Graphics
R12737 T18136 T18146 nmod Graphics,plugins
R12738 T18137 T18136 punct ",",Graphics
R12739 T18138 T18146 nmod Asheville,plugins
R12740 T18139 T18138 punct ",",Asheville
R12741 T18140 T18141 compound North,Carolina
R12742 T18141 T18138 conj Carolina,Asheville
R12743 T18142 T18141 punct ",",Carolina
R12744 T18143 T18144 compound United,States
R12745 T18144 T18141 appos States,Carolina
R12746 T18145 T18146 punct ),plugins
R12747 T18146 T18131 pobj plugins,with
R12748 T18147 T18111 punct .,processed
R12749 T18148 T18149 amod Original,images
R12750 T18149 T18150 nsubj images,are
R12751 T18150 T18150 ROOT are,are
R12752 T18151 T18150 acomp available,are
R12753 T18152 T18150 punct .,are
R12873 T18304 T18304 ROOT Histology,Histology
R12874 T18305 T18304 punct .,Histology
R12875 T18306 T18307 amod 18.5-dpc,embryos
R12876 T18307 T18309 nsubjpass embryos,exsanguinated
R12877 T18308 T18309 auxpass were,exsanguinated
R12878 T18309 T18309 ROOT exsanguinated,exsanguinated
R12879 T18310 T18309 cc and,exsanguinated
R12880 T18311 T18309 conj peripheral,exsanguinated
R12881 T18312 T18313 compound blood,smears
R12882 T18313 T18314 nsubj smears,were
R12883 T18314 T18315 auxpass were,prepared
R12884 T18315 T18309 conj prepared,exsanguinated
R12885 T18316 T18315 prep from,prepared
R12886 T18317 T18318 preconj both,mutant
R12887 T18318 T18321 amod mutant,mice
R12888 T18319 T18318 cc and,mutant
R12889 T18320 T18318 conj WT,mutant
R12890 T18321 T18316 pobj mice,from
R12891 T18322 T18309 punct .,exsanguinated
R12892 T18323 T18324 det The,slides
R12893 T18324 T18325 nsubj slides,were
R12894 T18325 T18325 ROOT were,were
R12895 T18326 T18325 acomp Wright-stained,were
R12896 T18327 T18325 cc and,were
R12897 T18328 T18325 conj read,were
R12898 T18329 T18328 agent by,read
R12899 T18330 T18329 pobj DAF,by
R12900 T18331 T18325 punct .,were
R12901 T18332 T18349 prep For,fixed
R12902 T18333 T18335 amod whole,analysis
R12903 T18334 T18335 compound mount,analysis
R12904 T18335 T18332 pobj analysis,For
R12905 T18336 T18349 punct ",",fixed
R12906 T18337 T18338 compound 14.5-dpc,WT
R12907 T18338 T18349 nsubjpass WT,fixed
R12908 T18339 T18338 cc and,WT
R12909 T18340 T18341 amod mutant,embryos
R12910 T18341 T18338 conj embryos,WT
R12911 T18342 T18341 punct ",",embryos
R12912 T18343 T18341 cc and,embryos
R12913 T18344 T18345 amod postnatal,day
R12914 T18345 T18349 npadvmod day,fixed
R12915 T18346 T18347 nummod 10.5,mice
R12916 T18347 T18349 nsubjpass mice,fixed
R12917 T18348 T18349 auxpass were,fixed
R12918 T18349 T18349 ROOT fixed,fixed
R12919 T18350 T18349 prep in,fixed
R12920 T18351 T18352 nummod 10,%
R12921 T18352 T18353 compound %,formalin
R12922 T18353 T18350 pobj formalin,in
R12923 T18354 T18353 punct ",",formalin
R12924 T18355 T18357 amod paraffin-embedded,sectioned
R12925 T18356 T18355 punct ",",paraffin-embedded
R12926 T18357 T18349 conj sectioned,fixed
R12927 T18358 T18357 prep at,sectioned
R12928 T18359 T18360 nummod 5,μm
R12929 T18360 T18358 pobj μm,at
R12930 T18361 T18357 punct ",",sectioned
R12931 T18362 T18357 cc and,sectioned
R12932 T18363 T18357 conj stained,sectioned
R12933 T18364 T18363 prep with,stained
R12934 T18365 T18364 pobj hematoxylin,with
R12935 T18366 T18365 cc and,hematoxylin
R12936 T18367 T18365 conj eosin,hematoxylin
R12937 T18368 T18349 punct .,fixed
R12938 T18369 T18370 compound Liver,samples
R12939 T18370 T18380 nsubjpass samples,prepared
R12940 T18371 T18372 punct (,at
R12941 T18372 T18370 prep at,samples
R12942 T18373 T18372 pobj 14.5,at
R12943 T18374 T18380 nsubjpass dpc,prepared
R12944 T18375 T18374 cc and,dpc
R12945 T18376 T18377 nummod 18.5,dpc
R12946 T18377 T18374 conj dpc,dpc
R12947 T18378 T18374 punct ),dpc
R12948 T18379 T18380 auxpass were,prepared
R12949 T18380 T18380 ROOT prepared,prepared
R12950 T18381 T18380 prep in,prepared
R12951 T18382 T18384 det a,manner
R12952 T18383 T18384 amod similar,manner
R12953 T18384 T18381 pobj manner,in
R12954 T18385 T18380 punct .,prepared
R12955 T18386 T18388 nsubjpass Images,obtained
R12956 T18387 T18388 auxpass were,obtained
R12957 T18388 T18388 ROOT obtained,obtained
R12958 T18389 T18388 prep with,obtained
R12959 T18390 T18392 compound Nikon,microscope
R12960 T18391 T18392 compound Labophot-2,microscope
R12961 T18392 T18389 pobj microscope,with
R12962 T18393 T18388 punct .,obtained
R12963 T18394 T18396 nsubj Objectives,were
R12964 T18395 T18394 acl used,Objectives
R12965 T18396 T18396 ROOT were,were
R12966 T18397 T18398 compound E,Plan
R12967 T18398 T18396 attr Plan,were
R12968 T18399 T18398 nummod 40/0,Plan
R12969 T18400 T18398 nummod .65,Plan
R12970 T18401 T18398 appos 160/0,Plan
R12971 T18402 T18403 nummod .17,Nikon
R12972 T18403 T18398 conj Nikon,Plan
R12973 T18404 T18403 punct (,Nikon
R12974 T18405 T18406 nummod 40,×
R12975 T18406 T18407 compound ×,objective
R12976 T18407 T18403 appos objective,Nikon
R12977 T18408 T18403 punct ),Nikon
R12978 T18409 T18403 punct ",",Nikon
R12979 T18410 T18411 compound E,Plan
R12980 T18411 T18398 conj Plan,Plan
R12981 T18412 T18411 nummod 100/1,Plan
R12982 T18413 T18398 appos .25,Plan
R12983 T18414 T18415 compound oil,160/0
R12984 T18415 T18417 nmod 160/0,Nikon
R12985 T18416 T18417 nummod .17,Nikon
R12986 T18417 T18398 conj Nikon,Plan
R12987 T18418 T18417 punct (,Nikon
R12988 T18419 T18421 nummod 100,objective
R12989 T18420 T18421 nummod ×,objective
R12990 T18421 T18417 appos objective,Nikon
R12991 T18422 T18417 punct ),Nikon
R12992 T18423 T18396 punct .,were
R12993 T18424 T18425 det The,camera
R12994 T18425 T18426 nsubj camera,was
R12995 T18426 T18426 ROOT was,was
R12996 T18427 T18429 det a,Coolpix
R12997 T18428 T18429 compound Nikon,Coolpix
R12998 T18429 T18430 compound Coolpix,4300
R12999 T18430 T18426 attr 4300,was
R13000 T18431 T18426 punct .,was
R13001 T18432 T18433 amod Original,images
R13002 T18433 T18434 nsubj images,are
R13003 T18434 T18434 ROOT are,are
R13004 T18435 T18434 acomp available,are
R13005 T18436 T18434 punct .,are
R13112 T18572 T18573 compound Northern,blot
R13113 T18573 T18573 ROOT blot,blot
R13114 T18574 T18573 punct .,blot
R13115 T18575 T18581 det A,filter
R13116 T18576 T18581 compound mouse,filter
R13117 T18577 T18578 amod embryonic,tissue
R13118 T18578 T18581 compound tissue,filter
R13119 T18579 T18580 compound Northern,blot
R13120 T18580 T18581 compound blot,filter
R13121 T18581 T18593 nsubjpass filter,hybridized
R13122 T18582 T18581 punct (,filter
R13123 T18583 T18581 appos Seegene,filter
R13124 T18584 T18583 punct ",",Seegene
R13125 T18585 T18583 conj Rockville,Seegene
R13126 T18586 T18585 punct ",",Rockville
R13127 T18587 T18585 conj Maryland,Rockville
R13128 T18588 T18587 punct ",",Maryland
R13129 T18589 T18590 compound United,States
R13130 T18590 T18587 appos States,Maryland
R13131 T18591 T18587 punct ),Maryland
R13132 T18592 T18593 auxpass was,hybridized
R13133 T18593 T18593 ROOT hybridized,hybridized
R13134 T18594 T18593 prep with,hybridized
R13135 T18595 T18597 det a,probe
R13136 T18596 T18597 amod Sox6,probe
R13137 T18597 T18594 pobj probe,with
R13138 T18598 T18597 acl generated,probe
R13139 T18599 T18598 agent by,generated
R13140 T18600 T18599 pobj RT-PCR,by
R13141 T18601 T18602 punct (,nucleotides
R13142 T18602 T18597 appos nucleotides,probe
R13143 T18603 T18602 nummod 1353,nucleotides
R13144 T18604 T18602 npadvmod 1927,nucleotides
R13145 T18605 T18602 punct ),nucleotides
R13146 T18606 T18593 cc and,hybridized
R13147 T18607 T18593 conj labeled,hybridized
R13148 T18608 T18607 prep with,labeled
R13149 T18609 T18612 compound [,dCTP
R13150 T18610 T18612 compound α-32P,dCTP
R13151 T18611 T18612 compound ],dCTP
R13152 T18612 T18608 pobj dCTP,with
R13153 T18613 T18612 punct ",",dCTP
R13154 T18614 T18607 agent by,labeled
R13155 T18615 T18616 amod random,primer
R13156 T18616 T18614 pobj primer,by
R13157 T18617 T18616 acl labeling,primer
R13158 T18618 T18619 punct (,RediprimeII
R13159 T18619 T18617 ccomp RediprimeII,labeling
R13160 T18620 T18619 punct ;,RediprimeII
R13161 T18621 T18622 compound Amersham,Biosciences
R13162 T18622 T18619 conj Biosciences,RediprimeII
R13163 T18623 T18622 punct ",",Biosciences
R13164 T18624 T18622 conj Buckinghamshire,Biosciences
R13165 T18625 T18624 punct ",",Buckinghamshire
R13166 T18626 T18624 conj England,Buckinghamshire
R13167 T18627 T18626 punct ",",England
R13168 T18628 T18629 compound United,Kingdom
R13169 T18629 T18619 npadvmod Kingdom,RediprimeII
R13170 T18630 T18619 punct ),RediprimeII
R13171 T18631 T18593 punct .,hybridized
R13172 T18632 T18633 det The,hybridization
R13173 T18633 T18635 nsubjpass hybridization,performed
R13174 T18634 T18635 auxpass was,performed
R13175 T18635 T18635 ROOT performed,performed
R13176 T18636 T18635 prep in,performed
R13177 T18637 T18636 pobj phosphate,in
R13178 T18638 T18635 advcl buffered,performed
R13179 T18639 T18640 nummod 7,%
R13180 T18640 T18643 compound %,solution
R13181 T18641 T18643 compound SDS,solution
R13182 T18642 T18643 compound hybridization,solution
R13183 T18643 T18638 dobj solution,buffered
R13184 T18644 T18635 punct .,performed
R13185 T18645 T18647 nsubjpass Blots,washed
R13186 T18646 T18647 auxpass were,washed
R13187 T18647 T18647 ROOT washed,washed
R13188 T18648 T18647 prep with,washed
R13189 T18649 T18651 nummod 0.2,SSC
R13190 T18650 T18651 nummod ×,SSC
R13191 T18651 T18648 pobj SSC,with
R13192 T18652 T18651 punct ",",SSC
R13193 T18653 T18654 nummod 1,%
R13194 T18654 T18655 compound %,SDS
R13195 T18655 T18651 appos SDS,SSC
R13196 T18656 T18647 prep at,washed
R13197 T18657 T18658 nummod 60,°
R13198 T18658 T18656 pobj °,at
R13199 T18659 T18660 compound C,prior
R13200 T18660 T18647 advmod prior,washed
R13201 T18661 T18660 prep to,prior
R13202 T18662 T18661 pobj exposure,to
R13203 T18663 T18662 prep to,exposure
R13204 T18664 T18665 compound X-ray,film
R13205 T18665 T18663 pobj film,to
R13206 T18666 T18667 punct (,Kodak
R13207 T18667 T18665 appos Kodak,film
R13208 T18668 T18667 punct ",",Kodak
R13209 T18669 T18667 conj Rochester,Kodak
R13210 T18670 T18669 punct ",",Rochester
R13211 T18671 T18672 compound New,York
R13212 T18672 T18669 conj York,Rochester
R13213 T18673 T18672 punct ",",York
R13214 T18674 T18675 compound United,States
R13215 T18675 T18672 appos States,York
R13216 T18676 T18672 punct ),York
R13217 T18677 T18660 prep at,prior
R13218 T18678 T18680 nummod −,°
R13219 T18679 T18680 nummod 80,°
R13220 T18680 T18677 pobj °,at
R13221 T18681 T18660 npadvmod C,prior
R13222 T18682 T18660 prep for,prior
R13223 T18683 T18684 nummod 6,d.
R13224 T18684 T18682 pobj d.,for
R13398 T18901 T18902 compound Cell,culture
R13399 T18902 T18902 ROOT culture,culture
R13400 T18903 T18902 cc and,culture
R13401 T18904 T18902 conj transfection,culture
R13402 T18905 T18902 punct .,culture
R13403 T18906 T18907 nummod GM979,cells
R13404 T18907 T18922 nsubjpass cells,cultured
R13405 T18908 T18907 punct (,cells
R13406 T18909 T18911 compound Coriell,Repositories
R13407 T18910 T18911 compound Cell,Repositories
R13408 T18911 T18907 appos Repositories,cells
R13409 T18912 T18911 punct ",",Repositories
R13410 T18913 T18911 conj Camden,Repositories
R13411 T18914 T18913 punct ",",Camden
R13412 T18915 T18916 compound New,Jersey
R13413 T18916 T18913 conj Jersey,Camden
R13414 T18917 T18916 punct ",",Jersey
R13415 T18918 T18919 compound United,States
R13416 T18919 T18916 appos States,Jersey
R13417 T18920 T18916 punct ),Jersey
R13418 T18921 T18922 auxpass were,cultured
R13419 T18922 T18922 ROOT cultured,cultured
R13420 T18923 T18922 prep in,cultured
R13421 T18924 T18926 poss Ham,F12
R13422 T18925 T18924 case 's,Ham
R13423 T18926 T18923 pobj F12,in
R13424 T18927 T18931 mark with,supplemented
R13425 T18928 T18930 nummod 2,L-glutamine
R13426 T18929 T18930 compound mM,L-glutamine
R13427 T18930 T18931 nsubj L-glutamine,supplemented
R13428 T18931 T18922 advcl supplemented,cultured
R13429 T18932 T18931 prep with,supplemented
R13430 T18933 T18938 amod heat-inactivated,serum
R13431 T18934 T18935 nummod 10,%
R13432 T18935 T18938 compound %,serum
R13433 T18936 T18937 amod fetal,calf
R13434 T18937 T18938 compound calf,serum
R13435 T18938 T18932 pobj serum,with
R13436 T18939 T18938 punct (,serum
R13437 T18940 T18968 nmod Ivitrogen,)
R13438 T18941 T18940 punct ",",Ivitrogen
R13439 T18942 T18940 conj Carlsbad,Ivitrogen
R13440 T18943 T18942 punct ",",Carlsbad
R13441 T18944 T18942 conj California,Carlsbad
R13442 T18945 T18944 punct ",",California
R13443 T18946 T18947 compound United,States
R13444 T18947 T18944 conj States,California
R13445 T18948 T18944 punct ),California
R13446 T18949 T18940 punct ",",Ivitrogen
R13447 T18950 T18967 nmod penicillin,mM
R13448 T18951 T18953 punct (,units/ml
R13449 T18952 T18953 nummod 100,units/ml
R13450 T18953 T18950 appos units/ml,penicillin
R13451 T18954 T18953 punct ),units/ml
R13452 T18955 T18950 punct ",",penicillin
R13453 T18956 T18960 nmod streptomycin,ml
R13454 T18957 T18956 nummod 100,streptomycin
R13455 T18958 T18960 compound μg,ml
R13456 T18959 T18960 compound /,ml
R13457 T18960 T18950 appos ml,penicillin
R13458 T18961 T18960 punct ),ml
R13459 T18962 T18950 punct ",",penicillin
R13460 T18963 T18950 cc and,penicillin
R13461 T18964 T18950 conj L-glutamine,penicillin
R13462 T18965 T18966 punct (,2
R13463 T18966 T18967 nummod 2,mM
R13464 T18967 T18940 appos mM,Ivitrogen
R13465 T18968 T18938 punct ),serum
R13466 T18969 T18922 punct .,cultured
R13467 T18970 T18971 compound MEL,cells
R13468 T18971 T18976 nsubjpass cells,supplemented
R13469 T18972 T18976 auxpass were,supplemented
R13470 T18973 T18972 acomp cultured,were
R13471 T18974 T18973 prep in,cultured
R13472 T18975 T18974 pobj DMEM,in
R13473 T18976 T18976 ROOT supplemented,supplemented
R13474 T18977 T18976 prep as,supplemented
R13475 T18978 T18977 prep above,as
R13476 T18979 T18978 punct (,above
R13477 T18980 T18978 prep without,above
R13478 T18981 T18980 pobj heat,without
R13479 T18982 T18978 pcomp inactivating,above
R13480 T18983 T18984 det the,serum
R13481 T18984 T18982 dobj serum,inactivating
R13482 T18985 T18977 punct ),as
R13483 T18986 T18976 punct .,supplemented
R13484 T18987 T18988 nummod GM979,cells
R13485 T18988 T19000 nsubjpass cells,transfected
R13486 T18989 T18988 punct (,cells
R13487 T18990 T18992 nummod 4,105
R13488 T18991 T18992 nummod ×,105
R13489 T18992 T18988 appos 105,cells
R13490 T18993 T18988 punct ),cells
R13491 T18994 T18988 prep in,cells
R13492 T18995 T18996 compound log,phase
R13493 T18996 T18994 pobj phase,in
R13494 T18997 T18996 prep of,phase
R13495 T18998 T18997 pobj growth,of
R13496 T18999 T19000 auxpass were,transfected
R13497 T19000 T19000 ROOT transfected,transfected
R13498 T19001 T19000 prep with,transfected
R13499 T19002 T19001 pobj plasmids,with
R13500 T19003 T19000 agent by,transfected
R13501 T19004 T19003 pobj FuGENE6,by
R13502 T19005 T19006 punct (,Roche
R13503 T19006 T19004 appos Roche,FuGENE6
R13504 T19007 T19006 punct ",",Roche
R13505 T19008 T19013 nmod Indianapolis,States
R13506 T19009 T19008 punct ",",Indianapolis
R13507 T19010 T19008 conj Indiana,Indianapolis
R13508 T19011 T19010 punct ",",Indiana
R13509 T19012 T19013 compound United,States
R13510 T19013 T19006 conj States,Roche
R13511 T19014 T19006 punct ),Roche
R13512 T19015 T19000 punct .,transfected
R13513 T19016 T19018 nsubjpass Cells,transfected
R13514 T19017 T19018 auxpass were,transfected
R13515 T19018 T19018 ROOT transfected,transfected
R13516 T19019 T19018 prep with,transfected
R13517 T19020 T19022 amod ɛy,reporter
R13518 T19021 T19022 compound promoter,reporter
R13519 T19022 T19023 compound reporter,constructs
R13520 T19023 T19019 pobj constructs,with
R13521 T19024 T19023 punct (,constructs
R13522 T19025 T19026 nummod 500,ng
R13523 T19026 T19023 appos ng,constructs
R13524 T19027 T19023 punct ),constructs
R13525 T19028 T19018 prep along,transfected
R13526 T19029 T19028 prep with,along
R13527 T19030 T19032 preconj either,vector
R13528 T19031 T19032 amod empty,vector
R13529 T19032 T19029 pobj vector,with
R13530 T19033 T19032 cc or,vector
R13531 T19034 T19036 amod Sox6,vector
R13532 T19035 T19036 compound overexpression,vector
R13533 T19036 T19032 conj vector,vector
R13534 T19037 T19036 punct (,vector
R13535 T19038 T19039 nummod 1000,ng
R13536 T19039 T19036 appos ng,vector
R13537 T19040 T19036 punct ),vector
R13538 T19041 T19018 punct .,transfected
R13539 T19042 T19049 prep In,used
R13540 T19043 T19042 pobj assays,In
R13541 T19044 T19043 prep of,assays
R13542 T19045 T19046 compound dosage,effect
R13543 T19046 T19044 pobj effect,of
R13544 T19047 T19049 punct ",",used
R13545 T19048 T19049 nsubj we,used
R13546 T19049 T19049 ROOT used,used
R13547 T19050 T19051 nummod 200,ng
R13548 T19051 T19049 dobj ng,used
R13549 T19052 T19051 punct ",",ng
R13550 T19053 T19054 nummod 500,ng
R13551 T19054 T19051 appos ng,ng
R13552 T19055 T19054 punct ",",ng
R13553 T19056 T19054 cc and,ng
R13554 T19057 T19058 nummod 1000,ng
R13555 T19058 T19054 conj ng,ng
R13556 T19059 T19051 punct ),ng
R13557 T19060 T19049 punct .,used
R13558 T19061 T19062 amod pRL-CMV,15ng
R13559 T19062 T19067 nsubjpass 15ng,used
R13560 T19063 T19064 punct (,Promega
R13561 T19064 T19062 appos Promega,15ng
R13562 T19065 T19064 punct ),Promega
R13563 T19066 T19067 auxpass was,used
R13564 T19067 T19067 ROOT used,used
R13565 T19068 T19067 prep as,used
R13566 T19069 T19070 det a,control
R13567 T19070 T19068 pobj control,as
R13568 T19071 T19070 prep for,control
R13569 T19072 T19073 compound transfection,efficiency
R13570 T19073 T19071 pobj efficiency,for
R13571 T19074 T19067 punct .,used
R13673 T19267 T19268 compound Nuclear,protein
R13674 T19268 T19269 nsubj protein,extract
R13675 T19269 T19269 ROOT extract,extract
R13676 T19270 T19269 cc and,extract
R13677 T19271 T19269 prep in,extract
R13678 T19272 T19273 amod vitro,translation
R13679 T19273 T19271 pobj translation,in
R13680 T19274 T19273 prep of,translation
R13681 T19275 T19274 pobj Sox6,of
R13682 T19276 T19269 punct .,extract
R13683 T19277 T19278 compound Nuclear,extracts
R13684 T19278 T19280 nsubjpass extracts,prepared
R13685 T19279 T19280 auxpass were,prepared
R13686 T19280 T19280 ROOT prepared,prepared
R13687 T19281 T19280 prep from,prepared
R13688 T19282 T19283 compound MEL,cells
R13689 T19283 T19281 pobj cells,from
R13690 T19284 T19283 punct (,cells
R13691 T19285 T19286 nummod 2,×
R13692 T19286 T19287 nummod ×,107
R13693 T19287 T19283 appos 107,cells
R13694 T19288 T19283 punct ),cells
R13695 T19289 T19280 advcl using,prepared
R13696 T19290 T19291 det a,kit
R13697 T19291 T19289 dobj kit,using
R13698 T19292 T19291 punct (,kit
R13699 T19293 T19294 amod Active,Motif
R13700 T19294 T19291 appos Motif,kit
R13701 T19295 T19294 punct ",",Motif
R13702 T19296 T19294 conj Carlsbad,Motif
R13703 T19297 T19296 punct ",",Carlsbad
R13704 T19298 T19296 conj California,Carlsbad
R13705 T19299 T19298 punct ",",California
R13706 T19300 T19301 compound United,States
R13707 T19301 T19298 conj States,California
R13708 T19302 T19296 punct ),Carlsbad
R13709 T19303 T19280 punct .,prepared
R13710 T19304 T19305 det The,Sox6
R13711 T19305 T19312 nsubjpass Sox6,tagged
R13712 T19306 T19312 prep in,tagged
R13713 T19307 T19309 amod vitro,expression
R13714 T19308 T19309 compound translation,expression
R13715 T19309 T19310 compound expression,vector
R13716 T19310 T19306 pobj vector,in
R13717 T19311 T19312 punct ",",tagged
R13718 T19312 T19312 ROOT tagged,tagged
R13719 T19313 T19312 prep with,tagged
R13720 T19314 T19313 pobj c-Myc,with
R13721 T19315 T19314 cc and,c-Myc
R13722 T19316 T19314 conj HA,c-Myc
R13723 T19317 T19319 punct ",",described
R13724 T19318 T19319 auxpass was,described
R13725 T19319 T19312 conj described,tagged
R13726 T19320 T19319 prep before,described
R13727 T19321 T19323 nmod [,]
R13728 T19322 T19321 nummod 15,[
R13729 T19323 T19320 pobj ],before
R13730 T19324 T19319 punct .,described
R13731 T19325 T19326 det The,translation
R13732 T19326 T19328 nsubjpass translation,performed
R13733 T19327 T19328 auxpass was,performed
R13734 T19328 T19328 ROOT performed,performed
R13735 T19329 T19328 prep in,performed
R13736 T19330 T19332 det a,lysate
R13737 T19331 T19332 amod reticulocyte,lysate
R13738 T19332 T19329 pobj lysate,in
R13739 T19333 T19332 acl based,lysate
R13740 T19334 T19333 prep in,based
R13741 T19335 T19337 amod vitro,system
R13742 T19336 T19337 amod translational,system
R13743 T19337 T19334 pobj system,in
R13744 T19338 T19337 punct (,system
R13745 T19339 T19344 nmod TNT,Systems
R13746 T19340 T19339 nummod ®,TNT
R13747 T19341 T19344 compound Quick,Systems
R13748 T19342 T19344 compound Coupled,Systems
R13749 T19343 T19344 compound Transcription/Translation,Systems
R13750 T19344 T19337 appos Systems,system
R13751 T19345 T19344 punct ",",Systems
R13752 T19346 T19344 appos Promega,Systems
R13753 T19347 T19337 punct ),system
R13754 T19348 T19328 punct .,performed
R13755 T19349 T19350 det A,vector
R13756 T19350 T19358 nsubjpass vector,translated
R13757 T19351 T19350 prep without,vector
R13758 T19352 T19355 det the,sequence
R13759 T19353 T19355 amod Sox6,sequence
R13760 T19354 T19355 compound coding,sequence
R13761 T19355 T19351 pobj sequence,without
R13762 T19356 T19358 auxpass was,translated
R13763 T19357 T19358 advmod also,translated
R13764 T19358 T19358 ROOT translated,translated
R13765 T19359 T19358 prep as,translated
R13766 T19360 T19362 det a,control
R13767 T19361 T19362 amod negative,control
R13768 T19362 T19359 pobj control,as
R13769 T19363 T19358 punct .,translated
R13850 T19522 T19522 ROOT Antibodies,Antibodies
R13851 T19523 T19522 punct .,Antibodies
R13852 T19524 T19525 amod Sox6,antibodies
R13853 T19525 T19530 nsubj antibodies,were
R13854 T19526 T19525 acl used,antibodies
R13855 T19527 T19526 prep in,used
R13856 T19528 T19529 det this,study
R13857 T19529 T19527 pobj study,in
R13858 T19530 T19533 auxpass were,provided
R13859 T19531 T19533 preconj either,provided
R13860 T19532 T19533 advmod kindly,provided
R13861 T19533 T19533 ROOT provided,provided
R13862 T19534 T19533 agent by,provided
R13863 T19535 T19537 compound Dr.,Lalli
R13864 T19536 T19537 compound Enzo,Lalli
R13865 T19537 T19534 pobj Lalli,by
R13866 T19538 T19541 punct (,Pasteur
R13867 T19539 T19541 compound Université,Pasteur
R13868 T19540 T19541 compound Louis,Pasteur
R13869 T19541 T19537 appos Pasteur,Lalli
R13870 T19542 T19541 punct ",",Pasteur
R13871 T19543 T19550 nsubj France,obtained
R13872 T19544 T19546 nmod [,]
R13873 T19545 T19546 nummod 7,]
R13874 T19546 T19543 nmod ],France
R13875 T19547 T19546 punct ),]
R13876 T19548 T19543 cc or,France
R13877 T19549 T19550 advmod commercially,obtained
R13878 T19550 T19533 conj obtained,provided
R13879 T19551 T19556 punct (,X
R13880 T19552 T19553 compound Catalog,No
R13881 T19553 T19556 nmod No,X
R13882 T19554 T19556 punct .,X
R13883 T19555 T19556 compound sc-17332,X
R13884 T19556 T19550 dobj X,obtained
R13885 T19557 T19556 punct ",",X
R13886 T19558 T19559 compound Santa,Cruz
R13887 T19559 T19560 compound Cruz,Biotechnology
R13888 T19560 T19556 conj Biotechnology,X
R13889 T19561 T19560 punct ",",Biotechnology
R13890 T19562 T19563 compound Santa,Cruz
R13891 T19563 T19560 conj Cruz,Biotechnology
R13892 T19564 T19563 punct ",",Cruz
R13893 T19565 T19563 conj California,Cruz
R13894 T19566 T19565 punct ",",California
R13895 T19567 T19568 compound United,States
R13896 T19568 T19565 conj States,California
R13897 T19569 T19550 punct ),obtained
R13898 T19570 T19533 punct .,provided
R13899 T19571 T19573 det All,antibodies
R13900 T19572 T19573 amod Sox6,antibodies
R13901 T19573 T19574 nsubj antibodies,generated
R13902 T19574 T19574 ROOT generated,generated
R13903 T19575 T19576 amod similar,results
R13904 T19576 T19574 dobj results,generated
R13905 T19577 T19574 punct .,generated
R13906 T19578 T19579 amod c-Myc,antibody
R13907 T19579 T19581 nsubjpass antibody,purchased
R13908 T19580 T19581 auxpass was,purchased
R13909 T19581 T19581 ROOT purchased,purchased
R13910 T19582 T19581 prep from,purchased
R13911 T19583 T19582 pobj Invitrogen,from
R13912 T19584 T19581 punct .,purchased
R13913 T19585 T19588 amod Normal,antibody
R13914 T19586 T19588 compound rabbit,antibody
R13915 T19587 T19588 compound IgG,antibody
R13916 T19588 T19590 nsubjpass antibody,obtained
R13917 T19589 T19590 auxpass was,obtained
R13918 T19590 T19590 ROOT obtained,obtained
R13919 T19591 T19590 prep from,obtained
R13920 T19592 T19593 compound Upstate,Biotechnology
R13921 T19593 T19591 pobj Biotechnology,from
R13922 T19594 T19596 punct (,Placid
R13923 T19595 T19596 compound Lake,Placid
R13924 T19596 T19593 appos Placid,Biotechnology
R13925 T19597 T19596 punct ",",Placid
R13926 T19598 T19599 compound New,York
R13927 T19599 T19596 npadvmod York,Placid
R13928 T19600 T19599 punct ",",York
R13929 T19601 T19602 compound United,States
R13930 T19602 T19599 appos States,York
R13931 T19603 T19596 punct ),Placid
R13932 T19604 T19590 punct .,obtained
R14199 T19985 T19985 ROOT EMSA,EMSA
R14200 T19986 T19985 punct .,EMSA
R14201 T19987 T19989 amod Single-stranded,oligonucleotides
R14202 T19988 T19989 amod complementary,oligonucleotides
R14203 T19989 T19990 nsubj oligonucleotides,were
R14204 T19990 T19990 ROOT were,were
R14205 T19991 T19990 acomp annealed,were
R14206 T19992 T19991 cc and,annealed
R14207 T19993 T19991 conj end-labeled,annealed
R14208 T19994 T19991 prep with,annealed
R14209 T19995 T19998 compound [,ATP
R14210 T19996 T19998 compound γ-32P,ATP
R14211 T19997 T19998 compound ],ATP
R14212 T19998 T19994 pobj ATP,with
R14213 T19999 T19994 prep with,with
R14214 T20000 T20002 nummod T4,kinase
R14215 T20001 T20002 compound polynucleotide,kinase
R14216 T20002 T19999 pobj kinase,with
R14217 T20003 T19990 punct .,were
R14218 T20004 T20006 nsubjpass EMSA,performed
R14219 T20005 T20006 auxpass was,performed
R14220 T20006 T20006 ROOT performed,performed
R14221 T20007 T20006 prep with,performed
R14222 T20008 T20009 nummod 5,μg
R14223 T20009 T20007 pobj μg,with
R14224 T20010 T20009 prep of,μg
R14225 T20011 T20012 amod nuclear,proteins
R14226 T20012 T20010 pobj proteins,of
R14227 T20013 T20009 prep from,μg
R14228 T20014 T20015 compound MEL,cells
R14229 T20015 T20013 pobj cells,from
R14230 T20016 T20015 cc or,cells
R14231 T20017 T20018 nummod 3,μl
R14232 T20018 T20015 conj μl,cells
R14233 T20019 T20018 prep of,μl
R14234 T20020 T20018 prep in,μl
R14235 T20021 T20022 amod vitro-translated,Sox6
R14236 T20022 T20020 pobj Sox6,in
R14237 T20023 T20009 prep along,μg
R14238 T20024 T20023 prep with,along
R14239 T20025 T20027 det the,lysate
R14240 T20026 T20027 compound reticulocyte,lysate
R14241 T20027 T20024 pobj lysate,with
R14242 T20028 T20027 prep in,lysate
R14243 T20029 T20030 amod binding,buffer
R14244 T20030 T20028 pobj buffer,in
R14245 T20031 T20009 punct :,μg
R14246 T20032 T20034 nummod 100,NaCl
R14247 T20033 T20034 compound mM,NaCl
R14248 T20034 T20009 appos NaCl,μg
R14249 T20035 T20034 punct ",",NaCl
R14250 T20036 T20037 nummod 10,%
R14251 T20037 T20038 compound %,glycerol
R14252 T20038 T20034 appos glycerol,NaCl
R14253 T20039 T20038 punct ",",glycerol
R14254 T20040 T20041 nummod 200,ng
R14255 T20041 T20050 npadvmod ng,poly
R14256 T20042 T20044 nmod /,BSA
R14257 T20043 T20044 compound μl,BSA
R14258 T20044 T20050 nmod BSA,poly
R14259 T20045 T20050 punct ",",poly
R14260 T20046 T20047 nummod 50,ng
R14261 T20047 T20050 compound ng,poly
R14262 T20048 T20050 compound /,poly
R14263 T20049 T20050 compound μl,poly
R14264 T20050 T20009 appos poly,μg
R14265 T20051 T20050 punct (,poly
R14266 T20052 T20050 appos dI-dC,poly
R14267 T20053 T20052 punct ),dI-dC
R14268 T20054 T20052 cc or,dI-dC
R14269 T20055 T20055 ROOT poly,poly
R14270 T20056 T20057 punct (,dG-dC
R14271 T20057 T20055 appos dG-dC,poly
R14272 T20058 T20057 punct ),dG-dC
R14273 T20059 T20055 punct ",",poly
R14274 T20060 T20062 nummod 10,HEPES
R14275 T20061 T20062 compound mM,HEPES
R14276 T20062 T20055 appos HEPES,poly
R14277 T20063 T20064 punct (,pH
R14278 T20064 T20062 parataxis pH,HEPES
R14279 T20065 T20064 nummod 7,pH
R14280 T20066 T20064 punct ),pH
R14281 T20067 T20064 punct ",",pH
R14282 T20068 T20070 nummod 0.1,EDTA
R14283 T20069 T20070 compound mM,EDTA
R14284 T20070 T20064 appos EDTA,pH
R14285 T20071 T20070 punct ",",EDTA
R14286 T20072 T20074 nummod 0.25,DTT
R14287 T20073 T20074 compound mM,DTT
R14288 T20074 T20070 appos DTT,EDTA
R14289 T20075 T20074 punct ",",DTT
R14290 T20076 T20078 nummod 0.6,MgCl2
R14291 T20077 T20078 compound mM,MgCl2
R14292 T20078 T20074 appos MgCl2,DTT
R14293 T20079 T20006 punct .,performed
R14294 T20080 T20103 prep For,added
R14295 T20081 T20080 pobj competition,For
R14296 T20082 T20081 cc or,competition
R14297 T20083 T20084 compound supershift,assays
R14298 T20084 T20081 conj assays,competition
R14299 T20085 T20084 punct ",",assays
R14300 T20086 T20090 det the,competitor
R14301 T20087 T20090 amod indicated,competitor
R14302 T20088 T20090 amod unlabelled,competitor
R14303 T20089 T20090 compound oligonucleotide,competitor
R14304 T20090 T20084 conj competitor,assays
R14305 T20091 T20090 punct (,competitor
R14306 T20092 T20094 amod 200-fold,excess
R14307 T20093 T20094 compound molar,excess
R14308 T20094 T20090 appos excess,competitor
R14309 T20095 T20090 punct ),competitor
R14310 T20096 T20090 cc or,competitor
R14311 T20097 T20090 conj antibody,competitor
R14312 T20098 T20097 punct (,antibody
R14313 T20099 T20100 nummod 3,μl
R14314 T20100 T20097 appos μl,antibody
R14315 T20101 T20097 punct ),antibody
R14316 T20102 T20103 auxpass was,added
R14317 T20103 T20103 ROOT added,added
R14318 T20104 T20107 quantmod 30,60
R14319 T20105 T20107 quantmod min,60
R14320 T20106 T20107 quantmod to,60
R14321 T20107 T20103 dobj 60,added
R14322 T20108 T20107 quantmod min,60
R14323 T20109 T20103 advmod prior,added
R14324 T20110 T20103 prep to,added
R14325 T20111 T20110 pobj addition,to
R14326 T20112 T20111 prep of,addition
R14327 T20113 T20114 amod radiolabeled,probe
R14328 T20114 T20112 pobj probe,of
R14329 T20115 T20103 punct .,added
R14330 T20116 T20126 prep Following,incubated
R14331 T20117 T20116 pobj addition,Following
R14332 T20118 T20117 prep of,addition
R14333 T20119 T20121 det the,probe
R14334 T20120 T20121 compound radiolabeled,probe
R14335 T20121 T20118 pobj probe,of
R14336 T20122 T20126 punct ",",incubated
R14337 T20123 T20124 det the,samples
R14338 T20124 T20126 nsubjpass samples,incubated
R14339 T20125 T20126 auxpass were,incubated
R14340 T20126 T20126 ROOT incubated,incubated
R14341 T20127 T20126 prep for,incubated
R14342 T20128 T20129 nummod 30,min
R14343 T20129 T20127 pobj min,for
R14344 T20130 T20129 cc or,min
R14345 T20131 T20132 nummod 60,min
R14346 T20132 T20129 conj min,min
R14347 T20133 T20132 prep at,min
R14348 T20134 T20135 compound room,temperature
R14349 T20135 T20133 pobj temperature,at
R14350 T20136 T20132 cc and,min
R14351 T20137 T20129 acl loaded,min
R14352 T20138 T20137 prep on,loaded
R14353 T20139 T20141 det a,%
R14354 T20140 T20141 nummod 4,%
R14355 T20141 T20138 pobj %,on
R14356 T20142 T20141 cc or,%
R14357 T20143 T20144 nummod 6,%
R14358 T20144 T20141 conj %,%
R14359 T20145 T20146 punct (,w/v
R14360 T20146 T20144 appos w/v,%
R14361 T20147 T20126 punct ),incubated
R14362 T20148 T20149 compound polyacrylamide,gel
R14363 T20149 T20149 ROOT gel,gel
R14364 T20150 T20149 punct .,gel
R14365 T20151 T20153 nsubjpass Electrophoresis,performed
R14366 T20152 T20153 auxpass was,performed
R14367 T20153 T20153 ROOT performed,performed
R14368 T20154 T20153 prep at,performed
R14369 T20155 T20158 det a,mAmp
R14370 T20156 T20158 amod constant,mAmp
R14371 T20157 T20158 nummod 19,mAmp
R14372 T20158 T20154 pobj mAmp,at
R14373 T20159 T20153 prep for,performed
R14374 T20160 T20159 pobj 4,for
R14375 T20161 T20162 nummod 8,h
R14376 T20162 T20171 nsubjpass h,dried
R14377 T20163 T20162 prep at,h
R14378 T20164 T20165 compound room,temperature
R14379 T20165 T20163 pobj temperature,at
R14380 T20166 T20162 punct ",",h
R14381 T20167 T20162 cc and,h
R14382 T20168 T20169 det the,gels
R14383 T20169 T20162 conj gels,h
R14384 T20170 T20171 auxpass were,dried
R14385 T20171 T20153 conj dried,performed
R14386 T20172 T20171 advmod prior,dried
R14387 T20173 T20172 prep to,prior
R14388 T20174 T20173 pobj autoradiography,to
R14389 T20175 T20171 punct .,dried
R14390 T20176 T20177 nsubj Antibodies,used
R14391 T20177 T20177 ROOT used,used
R14392 T20178 T20177 prep for,used
R14393 T20179 T20180 compound supershift,analyses
R14394 T20180 T20178 pobj analyses,for
R14395 T20181 T20177 conj included,used
R14396 T20182 T20188 nmod c-Myc,antibodies
R14397 T20183 T20182 punct ",",c-Myc
R14398 T20184 T20182 conj HA,c-Myc
R14399 T20185 T20184 punct ",",HA
R14400 T20186 T20184 cc and,HA
R14401 T20187 T20184 conj Sox6,HA
R14402 T20188 T20181 dobj antibodies,included
R14403 T20189 T20188 punct (,antibodies
R14404 T20190 T20188 acl described,antibodies
R14405 T20191 T20190 prep as,described
R14406 T20192 T20191 pcomp above,as
R14407 T20193 T20188 punct ),antibodies
R14408 T20194 T20177 punct .,used
R14409 T20195 T20197 det The,sequences
R14410 T20196 T20197 compound DNA,sequences
R14411 T20197 T20201 nsubj sequences,are
R14412 T20198 T20197 prep of,sequences
R14413 T20199 T20200 det the,oligonucleotides
R14414 T20200 T20198 pobj oligonucleotides,of
R14415 T20201 T20201 ROOT are,are
R14416 T20202 T20203 mark as,follows
R14417 T20203 T20201 advcl follows,are
R14418 T20204 T20209 punct (,listed
R14419 T20205 T20206 advmod only,forward
R14420 T20206 T20209 advmod forward,listed
R14421 T20207 T20209 nsubjpass oligos,listed
R14422 T20208 T20209 auxpass are,listed
R14423 T20209 T20201 advcl listed,are
R14424 T20210 T20209 punct ),listed
R14425 T20211 T20237 punct :,′
R14426 T20212 T20237 prep For,′
R14427 T20213 T20216 det the,probe
R14428 T20214 T20216 amod 36-bp,probe
R14429 T20215 T20216 compound WT,probe
R14430 T20216 T20212 pobj probe,For
R14431 T20217 T20237 punct :,′
R14432 T20218 T20221 nummod 5,′
R14433 T20219 T20221 nummod ′,′
R14434 T20220 T20221 compound AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3,′
R14435 T20221 T20237 npadvmod ′,′
R14436 T20222 T20223 punct (,MHB1556
R14437 T20223 T20221 appos MHB1556,′
R14438 T20224 T20223 punct ),MHB1556
R14439 T20225 T20237 punct ;,′
R14440 T20226 T20237 prep for,′
R14441 T20227 T20228 amod mutant,probe
R14442 T20228 T20226 pobj probe,for
R14443 T20229 T20228 nummod 1,probe
R14444 T20230 T20228 punct (,probe
R14445 T20231 T20228 appos M1,probe
R14446 T20232 T20228 punct ),probe
R14447 T20233 T20237 punct :,′
R14448 T20234 T20237 nummod 5,′
R14449 T20235 T20237 nummod ′,′
R14450 T20236 T20237 compound AACAAAGGGTCAGAACATTGTCTGCGAAG3,′
R14451 T20237 T20237 ROOT ′,′
R14452 T20238 T20239 punct (,MHB1644
R14453 T20239 T20237 appos MHB1644,′
R14454 T20240 T20239 punct ),MHB1644
R14455 T20241 T20253 punct ;,′
R14456 T20242 T20253 prep for,′
R14457 T20243 T20244 amod mutant,probe
R14458 T20244 T20242 pobj probe,for
R14459 T20245 T20244 nummod 2,probe
R14460 T20246 T20244 punct (,probe
R14461 T20247 T20244 appos M2,probe
R14462 T20248 T20244 punct ),probe
R14463 T20249 T20253 punct :,′
R14464 T20250 T20251 nummod 5,′
R14465 T20251 T20253 compound ′,′
R14466 T20252 T20253 compound AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3,′
R14467 T20253 T20237 conj ′,′
R14468 T20254 T20253 punct (,′
R14469 T20255 T20253 appos MHB1648,′
R14470 T20256 T20253 punct ),′
R14471 T20257 T20253 punct ;,′
R14472 T20258 T20258 ROOT for,for
R14473 T20259 T20260 amod mutant,probe
R14474 T20260 T20258 pobj probe,for
R14475 T20261 T20260 nummod 3,probe
R14476 T20262 T20260 punct (,probe
R14477 T20263 T20260 appos M3,probe
R14478 T20264 T20260 punct ),probe
R14479 T20265 T20258 punct :,for
R14480 T20266 T20267 nummod 5,′
R14481 T20267 T20269 compound ′,′
R14482 T20268 T20269 compound AATGCAGtgccAAGGGTCAGAACATTGTCTGCGAAG3,′
R14483 T20269 T20269 ROOT ′,′
R14484 T20270 T20269 punct (,′
R14485 T20271 T20269 appos MHB1650,′
R14486 T20272 T20269 punct ),′
R14487 T20273 T20237 punct .,′
R14776 T20678 T20679 compound ChIP,assay
R14777 T20679 T20679 ROOT assay,assay
R14778 T20680 T20679 punct .,assay
R14779 T20681 T20682 mark As,described
R14780 T20682 T20711 advcl described,treated
R14781 T20683 T20682 agent by,described
R14782 T20684 T20685 compound Nouzova,[
R14783 T20685 T20687 nmod [,]
R14784 T20686 T20687 nummod 53,]
R14785 T20687 T20683 pobj ],by
R14786 T20688 T20682 punct ",",described
R14787 T20689 T20682 prep in,described
R14788 T20690 T20689 pobj brief,in
R14789 T20691 T20711 punct :,treated
R14790 T20692 T20711 nsubjpass Cells,treated
R14791 T20693 T20692 prep from,Cells
R14792 T20694 T20695 compound MEL,cells
R14793 T20695 T20693 pobj cells,from
R14794 T20696 T20695 punct (,cells
R14795 T20697 T20699 nummod 4,107
R14796 T20698 T20699 nummod ×,107
R14797 T20699 T20695 appos 107,cells
R14798 T20700 T20699 punct ),107
R14799 T20701 T20699 cc or,107
R14800 T20702 T20704 amod fetal,cells
R14801 T20703 T20704 compound liver,cells
R14802 T20704 T20711 nsubjpass cells,treated
R14803 T20705 T20704 prep from,cells
R14804 T20706 T20709 nummod three,mice
R14805 T20707 T20709 amod 15.5-dpc,mice
R14806 T20708 T20709 compound WT,mice
R14807 T20709 T20705 pobj mice,from
R14808 T20710 T20711 auxpass were,treated
R14809 T20711 T20711 ROOT treated,treated
R14810 T20712 T20711 prep with,treated
R14811 T20713 T20714 nummod 1,%
R14812 T20714 T20715 compound %,formaldehyde
R14813 T20715 T20712 pobj formaldehyde,with
R14814 T20716 T20711 prep for,treated
R14815 T20717 T20718 nummod 10,min
R14816 T20718 T20716 pobj min,for
R14817 T20719 T20711 prep at,treated
R14818 T20720 T20721 nummod 37,°
R14819 T20721 T20722 nummod °,C
R14820 T20722 T20719 pobj C,at
R14821 T20723 T20711 punct ",",treated
R14822 T20724 T20711 conj rinsed,treated
R14823 T20725 T20724 prep in,rinsed
R14824 T20726 T20729 amod ice-cold,Hanks
R14825 T20727 T20728 nummod 1,×
R14826 T20728 T20729 compound ×,Hanks
R14827 T20729 T20733 poss Hanks,solution
R14828 T20730 T20729 case ',Hanks
R14829 T20731 T20733 amod balanced,solution
R14830 T20732 T20733 compound salt,solution
R14831 T20733 T20725 pobj solution,in
R14832 T20734 T20733 prep with,solution
R14833 T20735 T20736 nummod 0.1,%
R14834 T20736 T20737 compound %,EDTA
R14835 T20737 T20738 nsubj EDTA,containing
R14836 T20738 T20734 pcomp containing,with
R14837 T20739 T20740 compound protease,inhibitors
R14838 T20740 T20738 dobj inhibitors,containing
R14839 T20741 T20740 punct ",",inhibitors
R14840 T20742 T20740 acl collected,inhibitors
R14841 T20743 T20742 agent by,collected
R14842 T20744 T20743 pobj centrifugation,by
R14843 T20745 T20742 prep at,collected
R14844 T20746 T20747 nummod 4,°
R14845 T20747 T20748 nummod °,C
R14846 T20748 T20745 pobj C,at
R14847 T20749 T20748 punct ",",C
R14848 T20750 T20724 conj resuspended,rinsed
R14849 T20751 T20750 prep in,resuspended
R14850 T20752 T20755 det a,buffer
R14851 T20753 T20755 compound SDS,buffer
R14852 T20754 T20755 compound lysis,buffer
R14853 T20755 T20751 pobj buffer,in
R14854 T20756 T20755 acl containing,buffer
R14855 T20757 T20758 compound protease,inhibitors
R14856 T20758 T20756 dobj inhibitors,containing
R14857 T20759 T20750 punct ",",resuspended
R14858 T20760 T20750 cc and,resuspended
R14859 T20761 T20750 conj incubated,resuspended
R14860 T20762 T20761 prep on,incubated
R14861 T20763 T20762 pobj ice,on
R14862 T20764 T20761 prep for,incubated
R14863 T20765 T20766 nummod 10,min
R14864 T20766 T20764 pobj min,for
R14865 T20767 T20711 punct .,treated
R14866 T20768 T20769 amod DNA-protein,complexes
R14867 T20769 T20771 nsubjpass complexes,sonicated
R14868 T20770 T20771 auxpass were,sonicated
R14869 T20771 T20771 ROOT sonicated,sonicated
R14870 T20772 T20771 prep to,sonicated
R14871 T20773 T20776 nummod 200,bp
R14872 T20774 T20773 cc and,200
R14873 T20775 T20773 conj 600,200
R14874 T20776 T20772 pobj bp,to
R14875 T20777 T20771 punct .,sonicated
R14876 T20778 T20783 nsubjpass One-tenth,set
R14877 T20779 T20778 prep of,One-tenth
R14878 T20780 T20781 det the,sample
R14879 T20781 T20779 pobj sample,of
R14880 T20782 T20783 auxpass was,set
R14881 T20783 T20783 ROOT set,set
R14882 T20784 T20783 advmod aside,set
R14883 T20785 T20783 prep for,set
R14884 T20786 T20787 compound input,control
R14885 T20787 T20785 pobj control,for
R14886 T20788 T20783 punct ",",set
R14887 T20789 T20783 cc and,set
R14888 T20790 T20792 det the,sample
R14889 T20791 T20792 amod remaining,sample
R14890 T20792 T20794 nsubjpass sample,precleared
R14891 T20793 T20794 auxpass was,precleared
R14892 T20794 T20783 conj precleared,set
R14893 T20795 T20794 prep with,precleared
R14894 T20796 T20797 compound protein,A-Sepharose
R14895 T20797 T20795 pobj A-Sepharose,with
R14896 T20798 T20800 punct (,Biosciences
R14897 T20799 T20800 compound Amersham,Biosciences
R14898 T20800 T20797 appos Biosciences,A-Sepharose
R14899 T20801 T20800 punct ",",Biosciences
R14900 T20802 T20800 npadvmod Piscataway,Biosciences
R14901 T20803 T20802 punct ",",Piscataway
R14902 T20804 T20805 compound New,Jersey
R14903 T20805 T20802 conj Jersey,Piscataway
R14904 T20806 T20805 punct ",",Jersey
R14905 T20807 T20808 compound United,States
R14906 T20808 T20802 appos States,Piscataway
R14907 T20809 T20802 punct ),Piscataway
R14908 T20810 T20794 punct .,precleared
R14909 T20811 T20817 prep Following,split
R14910 T20812 T20811 pobj preclearing,Following
R14911 T20813 T20817 punct ",",split
R14912 T20814 T20815 det the,samples
R14913 T20815 T20817 nsubjpass samples,split
R14914 T20816 T20817 auxpass were,split
R14915 T20817 T20817 ROOT split,split
R14916 T20818 T20817 prep into,split
R14917 T20819 T20818 pobj thirds,into
R14918 T20820 T20817 punct :,split
R14919 T20821 T20822 nummod one,sample
R14920 T20822 T20829 nsubjpass sample,treated
R14921 T20823 T20822 acl treated,sample
R14922 T20824 T20823 prep with,treated
R14923 T20825 T20824 pobj anti-Sox6,with
R14924 T20826 T20825 punct ",",anti-Sox6
R14925 T20827 T20828 det a,second
R14926 T20828 T20829 amod second,treated
R14927 T20829 T20817 conj treated,split
R14928 T20830 T20829 prep with,treated
R14929 T20831 T20832 amod normal,rabbit
R14930 T20832 T20833 compound rabbit,IgG
R14931 T20833 T20830 pobj IgG,with
R14932 T20834 T20829 punct ",",treated
R14933 T20835 T20829 cc and,treated
R14934 T20836 T20838 det the,sample
R14935 T20837 T20838 amod third,sample
R14936 T20838 T20829 conj sample,treated
R14937 T20839 T20838 prep without,sample
R14938 T20840 T20839 pobj Ab,without
R14939 T20841 T20829 punct .,treated
R14940 T20842 T20844 det The,two
R14941 T20843 T20844 amod last,two
R14942 T20844 T20846 nsubjpass two,used
R14943 T20845 T20846 auxpass were,used
R14944 T20846 T20846 ROOT used,used
R14945 T20847 T20846 prep as,used
R14946 T20848 T20849 amod negative,controls
R14947 T20849 T20847 pobj controls,as
R14948 T20850 T20846 punct .,used
R14949 T20851 T20853 det The,complexes
R14950 T20852 T20853 amod chromatin-antibody,complexes
R14951 T20853 T20855 nsubjpass complexes,eluted
R14952 T20854 T20855 auxpass were,eluted
R14953 T20855 T20855 ROOT eluted,eluted
R14954 T20856 T20855 punct ",",eluted
R14955 T20857 T20855 cc and,eluted
R14956 T20858 T20860 det the,protein
R14957 T20859 T20860 compound DNA,protein
R14958 T20860 T20861 compound protein,cross-links
R14959 T20861 T20863 nsubjpass cross-links,reversed
R14960 T20862 T20863 auxpass were,reversed
R14961 T20863 T20855 conj reversed,eluted
R14962 T20864 T20863 prep with,reversed
R14963 T20865 T20867 nummod 5,NaCl
R14964 T20866 T20867 compound M,NaCl
R14965 T20867 T20864 pobj NaCl,with
R14966 T20868 T20863 prep at,reversed
R14967 T20869 T20871 nummod 65,C
R14968 T20870 T20871 nummod °,C
R14969 T20871 T20868 pobj C,at
R14970 T20872 T20863 prep for,reversed
R14971 T20873 T20874 nummod 4,h.
R14972 T20874 T20876 compound h.,DNA
R14973 T20875 T20876 compound Input,DNA
R14974 T20876 T20872 pobj DNA,for
R14975 T20877 T20876 cc or,DNA
R14976 T20878 T20879 amod immunoprecipitated,DNA
R14977 T20879 T20876 conj DNA,DNA
R14978 T20880 T20881 auxpass was,used
R14979 T20881 T20863 conj used,reversed
R14980 T20882 T20881 prep as,used
R14981 T20883 T20884 det a,template
R14982 T20884 T20882 pobj template,as
R14983 T20885 T20884 prep in,template
R14984 T20886 T20888 det the,reaction
R14985 T20887 T20888 compound PCR,reaction
R14986 T20888 T20885 pobj reaction,in
R14987 T20889 T20863 punct .,reversed
R14988 T20890 T20891 compound PCR,amplification
R14989 T20891 T20897 nsubjpass amplification,performed
R14990 T20892 T20891 prep of,amplification
R14991 T20893 T20895 det the,promoter
R14992 T20894 T20895 amod ɛy,promoter
R14993 T20895 T20892 pobj promoter,of
R14994 T20896 T20897 auxpass was,performed
R14995 T20897 T20897 ROOT performed,performed
R14996 T20898 T20897 cc and,performed
R14997 T20899 T20897 conj yielded,performed
R14998 T20900 T20902 det a,amplicon
R14999 T20901 T20902 amod 172-bp,amplicon
R15000 T20902 T20899 dobj amplicon,yielded
R15001 T20903 T20902 punct ",",amplicon
R15002 T20904 T20902 amod corresponding,amplicon
R15003 T20905 T20907 aux to,−
R15004 T20906 T20905 pobj nucleotides,to
R15005 T20907 T20904 xcomp −,corresponding
R15006 T20908 T20910 quantmod 31,+140
R15007 T20909 T20910 quantmod to,+140
R15008 T20910 T20907 dobj +140,−
R15009 T20911 T20910 prep of,+140
R15010 T20912 T20914 det the,promoter
R15011 T20913 T20914 amod ɛy,promoter
R15012 T20914 T20911 pobj promoter,of
R15013 T20915 T20916 punct (,primers
R15014 T20916 T20914 appos primers,promoter
R15015 T20917 T20922 nmod MHB1688,′
R15016 T20918 T20917 punct ",",MHB1688
R15017 T20919 T20920 nummod 5,′
R15018 T20920 T20922 nmod ′,′
R15019 T20921 T20922 nummod CGAAGAATAAAAGGCCACCA3,′
R15020 T20922 T20916 dobj ′,primers
R15021 T20923 T20916 punct ;,primers
R15022 T20924 T20916 cc and,primers
R15023 T20925 T20916 conj MHB1689,primers
R15024 T20926 T20925 punct ",",MHB1689
R15025 T20927 T20928 nummod 5,′
R15026 T20928 T20930 compound ′,′
R15027 T20929 T20930 compound GCTTCACCACCAACCTCTTC3,′
R15028 T20930 T20925 conj ′,MHB1689
R15029 T20931 T20930 punct ),′
R15030 T20932 T20897 punct .,performed
R15031 T20933 T20935 nsubjpass PCR,performed
R15032 T20934 T20935 auxpass was,performed
R15033 T20935 T20935 ROOT performed,performed
R15034 T20936 T20935 prep under,performed
R15035 T20937 T20939 det the,conditions
R15036 T20938 T20939 amod following,conditions
R15037 T20939 T20936 pobj conditions,under
R15038 T20940 T20939 punct :,conditions
R15039 T20941 T20942 nummod 95,°
R15040 T20942 T20943 compound °,C
R15041 T20943 T20939 appos C,conditions
R15042 T20944 T20943 prep for,C
R15043 T20945 T20946 nummod 15,min
R15044 T20946 T20944 pobj min,for
R15045 T20947 T20939 acl followed,conditions
R15046 T20948 T20947 agent by,followed
R15047 T20949 T20950 nummod 30,cycles
R15048 T20950 T20948 pobj cycles,by
R15049 T20951 T20950 prep at,cycles
R15050 T20952 T20951 pobj 95,at
R15051 T20953 T20954 nummod °,C
R15052 T20954 T20950 conj C,cycles
R15053 T20955 T20947 prep for,followed
R15054 T20956 T20955 pobj 30,for
R15055 T20957 T20939 appos s,conditions
R15056 T20958 T20935 punct ",",performed
R15057 T20959 T20960 nummod 60,°
R15058 T20960 T20961 compound °,C
R15059 T20961 T20935 npadvmod C,performed
R15060 T20962 T20935 prep for,performed
R15061 T20963 T20962 pobj 30,for
R15062 T20964 T20935 dep s,performed
R15063 T20965 T20935 punct ",",performed
R15064 T20966 T20935 cc and,performed
R15065 T20967 T20969 nummod 72,C
R15066 T20968 T20969 compound °,C
R15067 T20969 T20935 conj C,performed
R15068 T20970 T20969 prep for,C
R15069 T20971 T20970 pobj 45,for
R15070 T20972 T20969 appos s,C
R15071 T20973 T20969 punct ",",C
R15072 T20974 T20935 advcl ending,performed
R15073 T20975 T20974 prep with,ending
R15074 T20976 T20978 det a,extension
R15075 T20977 T20978 amod final,extension
R15076 T20978 T20975 pobj extension,with
R15077 T20979 T20978 prep at,extension
R15078 T20980 T20981 nummod 72,°
R15079 T20981 T20979 pobj °,at
R15080 T20982 T20978 npadvmod C,extension
R15081 T20983 T20978 prep for,extension
R15082 T20984 T20985 nummod 5,min
R15083 T20985 T20983 pobj min,for
R15084 T20986 T20935 punct .,performed
R1907 T2913 T2916 compound Sry,box
R1909 T2914 T2916 compound type,box
R1914 T2915 T2916 compound HMG,box
R1918 T2916 T2920 nsubj box,is
R1921 T2917 T2918 punct (,Sox6
R1922 T2918 T2916 appos Sox6,box
R1923 T2919 T2916 punct ),box
R1924 T2920 T2920 ROOT is,is
R1925 T2921 T2922 det a,member
R1926 T2922 T2920 attr member,is
R1927 T2926 T2927 compound transcription,factor
R1928 T2923 T2922 prep of,member
R1929 T2927 T2928 compound factor,family
R1930 T2928 T2923 pobj family,of
R1931 T2929 T2922 acl characterized,member
R1932 T2924 T2928 det the,family
R1933 T2930 T2929 agent by,characterized
R1934 T2931 T2935 det the,group
R1935 T2925 T2928 compound Sox,family
R1936 T2932 T2935 amod conserved,group
R1937 T2933 T2935 amod high,group
R1938 T2934 T2935 compound mobility,group
R1939 T3023 T3025 amod DNA-bound,factors
R1940 T2935 T2930 pobj group,by
R1941 T2936 T2937 punct (,HMG
R1942 T2937 T2935 appos HMG,group
R1943 T2938 T2937 punct ),HMG
R1944 T3024 T3025 compound transcription,factors
R1945 T2939 T2935 conj domain,group
R1946 T2940 T2935 punct ",",group
R1947 T2941 T2935 acl consisting,group
R1948 T3025 T3021 dobj factors,assembling
R1949 T2942 T2941 prep of,consisting
R1950 T2943 T2945 nummod 79,acids
R1951 T3026 T3021 prep into,assembling
R1952 T2944 T2945 compound amino,acids
R1953 T2945 T2942 pobj acids,of
R1954 T2946 T2945 acl involved,acids
R1955 T3027 T3028 advmod biologically,active
R1956 T2947 T2946 prep in,involved
R1957 T2948 T2949 compound DNA,recognition
R1958 T2949 T2947 pobj recognition,in
R1959 T3028 T3033 amod active,complexes
R1960 T2950 T2949 cc and,recognition
R1961 T2951 T2952 amod binding,[
R1962 T2952 T2949 conj [,recognition
R1963 T2953 T2954 nummod 1,]
R1964 T3029 T3033 punct ",",complexes
R1965 T2954 T2952 appos ],[
R1966 T2955 T2920 punct .,is
R1967 T3030 T3031 advmod sterically,defined
R1968 T2956 T2959 nsubj Sox,bind
R1969 T2957 T2958 compound transcription,factors
R1970 T2958 T2959 nsubj factors,bind
R1971 T3031 T3033 amod defined,complexes
R1972 T2959 T2959 ROOT bind,bind
R1973 T2960 T2959 prep to,bind
R1974 T3032 T3033 compound multiprotein,complexes
R1975 T2961 T2963 det the,groove
R1976 T2962 T2963 amod minor,groove
R1977 T3033 T3026 pobj complexes,into
R1978 T2963 T2960 pobj groove,to
R1979 T2964 T2963 prep of,groove
R1980 T2965 T2964 pobj DNA,of
R1981 T2966 T2959 cc and,bind
R1982 T2967 T2959 conj cause,bind
R1983 T2968 T2970 det a,°
R1984 T3034 T3007 punct .,perform
R1985 T2969 T2970 nummod 70,°
R1986 T2970 T2967 dobj °,cause
R1987 T2971 T2973 nummod 85,bend
R1988 T3035 T3038 nsubjpass Sox6,reported
R1989 T2972 T2973 compound °,bend
R1990 T2973 T2970 appos bend,°
R1991 T2974 T2973 prep of,bend
R1992 T3036 T3038 aux has,reported
R1993 T2975 T2976 det the,DNA
R1994 T2976 T2974 pobj DNA,of
R1995 T2977 T2978 nsubj that,leads
R1996 T3037 T3038 auxpass been,reported
R1997 T2978 T2976 relcl leads,DNA
R1998 T2979 T2978 prep to,leads
R1999 T2980 T2982 amod local,changes
R2000 T2981 T2982 amod conformational,changes
R2001 T3038 T3038 ROOT reported,reported
R2002 T2982 T2979 pobj changes,to
R2003 T2983 T2985 compound [,]
R2004 T3039 T3040 aux to,be
R2005 T2984 T2985 compound "2,3",]
R2006 T2985 T2982 appos ],changes
R2007 T2986 T2973 punct ",",bend
R2008 T3040 T3038 xcomp be,reported
R2009 T2987 T2992 mark while,target
R2010 T2988 T2991 amod most,factors
R2011 T2989 T2991 amod other,factors
R2012 T3041 T3040 acomp able,be
R2013 T2990 T2991 compound transcription,factors
R2014 T2991 T2992 nsubj factors,target
R2015 T2992 T2973 advcl target,bend
R2016 T2993 T2995 det the,groove
R2017 T2994 T2995 amod major,groove
R2018 T2995 T2992 dobj groove,target
R2019 T2996 T2995 prep of,groove
R2020 T2997 T3000 compound DNA,]
R2021 T3042 T3043 aux to,act
R2022 T2998 T3000 nmod [,]
R2023 T2999 T3000 nummod 4,]
R2024 T3000 T2996 pobj ],of
R2025 T3043 T3041 xcomp act,able
R2026 T3001 T2959 punct .,bind
R2027 T3002 T3007 advmod Therefore,perform
R2028 T3044 T3043 prep as,act
R2029 T3003 T3007 punct ",",perform
R2030 T3004 T3005 compound Sox,proteins
R2031 T3005 T3007 nsubj proteins,perform
R2032 T3045 T3047 preconj either,activator
R2033 T3006 T3007 aux may,perform
R2034 T3007 T3007 ROOT perform,perform
R2035 T3008 T3007 dobj part,perform
R2036 T3046 T3047 det an,activator
R2037 T3009 T3008 prep of,part
R2038 T3010 T3011 poss their,function
R2039 T3047 T3044 pobj activator,as
R2040 T3011 T3009 pobj function,of
R2041 T3012 T3007 prep as,perform
R2042 T3013 T3014 amod architectural,proteins
R2043 T3048 T3047 cc or,activator
R2044 T3014 T3012 pobj proteins,as
R2045 T3015 T3007 prep by,perform
R2046 T3016 T3015 pcomp organizing,by
R2047 T3049 T3050 det a,repressor
R2048 T3017 T3019 amod local,structure
R2049 T3018 T3019 compound chromatin,structure
R2050 T3050 T3047 conj repressor,activator
R2051 T3019 T3016 dobj structure,organizing
R2052 T3020 T3016 cc and,organizing
R2053 T3021 T3016 conj assembling,organizing
R2054 T3051 T3050 punct ",",repressor
R2055 T3022 T3025 amod other,factors
R2056 T3052 T3043 prep depending,act
R2057 T3053 T3052 prep on,depending
R2058 T3054 T3055 poss its,interactors
R2059 T3055 T3053 pobj interactors,on
R2060 T3056 T3055 cc and,interactors
R2061 T3120 T3118 punct ",",restored
R2062 T3057 T3060 poss its,context
R2063 T3121 T3118 advcl indicating,restored
R2064 T3122 T3123 amod functional,overlap
R2065 T3123 T3121 dobj overlap,indicating
R2066 T3124 T3123 prep of,overlap
R2067 T3125 T3126 det these,proteins
R2068 T3058 T3059 compound target,promoter
R2069 T3126 T3124 pobj proteins,of
R2070 T3127 T3123 conj [,overlap
R2071 T3128 T3129 nummod 7,]
R2072 T3059 T3060 compound promoter,context
R2073 T3129 T3127 dobj ],[
R2074 T3130 T3118 punct .,restored
R2075 T3131 T3131 ROOT Regardless,Regardless
R2076 T3060 T3052 conj context,depending
R2077 T3132 T3131 prep of,Regardless
R2078 T3133 T3144 advmod how,demonstrated
R2079 T3134 T3135 amod Sox6,functions
R2080 T3061 T3063 compound [,]
R2081 T3135 T3144 nsubj functions,demonstrated
R2082 T3136 T3135 prep in,functions
R2083 T3062 T3063 compound "5,6",]
R2084 T3137 T3136 pcomp regulating,in
R2085 T3138 T3139 compound gene,expression
R2086 T3063 T3060 appos ],context
R2087 T3139 T3137 dobj expression,regulating
R2088 T3140 T3144 punct ",",demonstrated
R2089 T3141 T3142 amod previous,studies
R2090 T3064 T3038 punct .,reported
R2091 T3142 T3144 nsubj studies,demonstrated
R2092 T3143 T3144 aux have,demonstrated
R2093 T3144 T3132 pcomp demonstrated,of
R2094 T3065 T3071 advmod Intriguingly,shown
R2095 T3145 T3147 mark that,is
R2096 T3146 T3147 nsubj Sox6,is
R2097 T3147 T3144 ccomp is,demonstrated
R2098 T3066 T3071 punct ",",shown
R2099 T3148 T3151 det an,molecule
R2100 T3149 T3151 amod important,molecule
R2101 T3150 T3151 amod regulatory,molecule
R2102 T3067 T3071 nsubj Sox6,shown
R2103 T3151 T3147 attr molecule,is
R2104 T3152 T3153 nsubj that,plays
R2105 T3068 T3071 aux has,shown
R2106 T3153 T3151 relcl plays,molecule
R2107 T3154 T3155 det a,role
R2108 T3155 T3153 dobj role,plays
R2109 T3156 T3155 prep in,role
R2110 T3069 T3071 advmod also,shown
R2111 T3157 T3158 det the,development
R2112 T3158 T3156 pobj development,in
R2113 T3159 T3158 prep of,development
R2114 T3160 T3163 det the,system
R2115 T3161 T3163 amod central,system
R2116 T3162 T3163 amod nervous,system
R2117 T3070 T3071 auxpass been,shown
R2118 T3163 T3159 pobj system,of
R2119 T3164 T3172 nmod [,]
R2120 T3165 T3164 nummod 8,[
R2121 T3071 T3071 ROOT shown,shown
R2122 T3166 T3167 nummod 11,]
R2123 T3167 T3164 appos ],[
R2124 T3168 T3169 punct ",",cartilage
R2125 T3169 T3164 conj cartilage,[
R2126 T3072 T3073 aux to,act
R2127 T3170 T3172 compound [,]
R2128 T3171 T3172 compound "6,12,13",]
R2129 T3172 T3153 npadvmod ],plays
R2130 T3073 T3071 xcomp act,shown
R2131 T3173 T3172 punct ",",]
R2132 T3174 T3172 cc and,]
R2133 T3074 T3073 prep as,act
R2134 T3175 T3178 compound muscle,]
R2135 T3176 T3178 compound [,]
R2136 T3075 T3078 det a,factor
R2137 T3177 T3178 compound "14,15",]
R2138 T3178 T3172 conj ],]
R2139 T3179 T3131 punct .,Regardless
R2140 T3076 T3078 amod general,factor
R2141 T3180 T3183 det A,mouse
R2142 T3181 T3183 amod Sox6-null,mouse
R2143 T3182 T3183 amod mutant,mouse
R2144 T3077 T3078 compound splicing,factor
R2145 T3183 T3190 nsubjpass mouse,identified
R2146 T3184 T3185 punct (,p100H
R2147 T3185 T3183 appos p100H,mouse
R2148 T3078 T3074 pobj factor,as
R2149 T3186 T3185 punct ),p100H
R2150 T3187 T3190 aux has,identified
R2151 T3188 T3190 advmod previously,identified
R2152 T3079 T3080 nsubj that,participates
R2153 T3080 T3078 relcl participates,factor
R2154 T3189 T3190 auxpass been,identified
R2155 T3190 T3190 ROOT identified,identified
R2156 T3191 T3190 prep in,identified
R2157 T3081 T3080 prep in,participates
R2158 T3192 T3193 poss our,laboratory
R2159 T3193 T3191 pobj laboratory,in
R2160 T3082 T3084 amod pre-mRNA,[
R2161 T3194 T3196 nmod [,]
R2162 T3195 T3196 nummod 14,]
R2163 T3196 T3190 dobj ],identified
R2164 T3197 T3190 punct .,identified
R2165 T3198 T3199 compound Mice,homozygous
R2166 T3199 T3206 nsubj homozygous,develop
R2167 T3083 T3084 compound splicing,[
R2168 T3200 T3199 prep for,homozygous
R2169 T3201 T3202 amod p100H,show
R2170 T3202 T3200 pobj show,for
R2171 T3084 T3086 nmod [,]
R2172 T3203 T3204 amod delayed,growth
R2173 T3204 T3202 dobj growth,show
R2174 T3085 T3086 nummod 7,]
R2175 T3205 T3202 punct ",",show
R2176 T3206 T3206 ROOT develop,develop
R2177 T3207 T3211 nmod myopathy,block
R2178 T3086 T3081 pobj ],in
R2179 T3208 T3207 cc and,myopathy
R2180 T3209 T3207 conj arterioventricular,myopathy
R2181 T3210 T3211 compound heart,block
R2182 T3211 T3206 dobj block,develop
R2183 T3087 T3071 punct .,shown
R2184 T3212 T3206 punct ",",develop
R2185 T3213 T3206 cc and,develop
R2186 T3214 T3206 conj die,develop
R2187 T3088 T3095 nsubj Depletion,blocked
R2188 T3215 T3214 prep within,die
R2189 T3216 T3217 nummod 2,wk
R2190 T3089 T3088 prep of,Depletion
R2191 T3090 T3089 pobj Sox6,of
R2192 T3091 T3090 prep in,Sox6
R2193 T3217 T3215 pobj wk,within
R2194 T3218 T3214 prep after,die
R2195 T3219 T3218 pobj birth,after
R2196 T3092 T3093 compound HeLa,cell
R2197 T3220 T3222 nmod [,]
R2198 T3221 T3222 nummod 14,]
R2199 T3093 T3094 compound cell,extracts
R2200 T3222 T3214 conj ],die
R2201 T3223 T3206 punct .,develop
R2202 T3224 T3227 det The,allele
R2203 T3094 T3095 nsubj extracts,blocked
R2204 T3225 T3227 amod p100H,allele
R2205 T3226 T3227 amod mutant,allele
R2206 T3227 T3229 nsubjpass allele,associated
R2207 T3095 T3095 ROOT blocked,blocked
R2208 T3228 T3229 auxpass is,associated
R2209 T3229 T3229 ROOT associated,associated
R2210 T3096 T3095 dobj splicing,blocked
R2211 T3230 T3229 prep with,associated
R2212 T3231 T3234 det a,inversion
R2213 T3232 T3234 nmod Chromosome,inversion
R2214 T3233 T3232 nummod 7,Chromosome
R2215 T3234 T3230 pobj inversion,with
R2216 T3235 T3236 nsubj that,disrupts
R2217 T3097 T3096 prep of,splicing
R2218 T3236 T3234 relcl disrupts,inversion
R2219 T3237 T3240 preconj both,gene
R2220 T3238 T3240 det the,gene
R2221 T3098 T3099 amod multiple,substrates
R2222 T3239 T3240 compound p,gene
R2223 T3240 T3236 dobj gene,disrupts
R2224 T3241 T3240 cc and,gene
R2225 T3099 T3097 pobj substrates,of
R2226 T3242 T3244 det the,gene
R2227 T3243 T3244 compound Sox6,gene
R2228 T3244 T3240 conj gene,gene
R2229 T3100 T3095 punct ",",blocked
R2230 T3245 T3244 punct (,gene
R2231 T3246 T3244 cc and,gene
R2232 T3247 T3249 det no,gene
R2233 T3101 T3095 cc and,blocked
R2234 T3248 T3249 amod other,gene
R2235 T3249 T3244 conj gene,gene
R2236 T3250 T3249 prep within,gene
R2237 T3102 T3095 conj expression,blocked
R2238 T3251 T3252 nummod "50,000",nucleotides
R2239 T3252 T3250 pobj nucleotides,within
R2240 T3103 T3102 prep of,expression
R2241 T3253 T3252 prep of,nucleotides
R2242 T3254 T3256 det the,breakpoints
R2243 T3255 T3256 amod chromosomal,breakpoints
R2244 T3104 T3106 det the,domain
R2245 T3256 T3253 pobj breakpoints,of
R2246 T3257 T3229 punct ),associated
R2247 T3105 T3106 compound HMG,domain
R2248 T3258 T3260 nmod [,]
R2249 T3259 T3260 nummod 14,]
R2250 T3260 T3260 ROOT ],]
R2251 T3261 T3260 punct .,]
R2252 T3106 T3103 pobj domain,of
R2253 T3262 T3279 mark Because,implicated
R2254 T3263 T3266 det the,functions
R2255 T3107 T3106 prep of,domain
R2256 T3264 T3265 compound p,gene
R2257 T3265 T3266 compound gene,functions
R2258 T3266 T3279 advcl functions,implicated
R2259 T3108 T3118 preconj either,restored
R2260 T3267 T3268 advmod solely,in
R2261 T3268 T3266 prep in,functions
R2262 T3109 T3118 nsubj Sox6,restored
R2263 T3269 T3268 pobj pigmentation,in
R2264 T3110 T3109 punct ",",Sox6
R2265 T3270 T3272 nmod [,]
R2266 T3271 T3272 nummod 16,]
R2267 T3272 T3266 appos ],functions
R2268 T3273 T3279 punct ",",implicated
R2269 T3274 T3277 det the,factor
R2270 T3111 T3109 conj Sox9,Sox6
R2271 T3275 T3277 compound Sox6,factor
R2272 T3276 T3277 compound transcription,factor
R2273 T3112 T3111 punct ",",Sox9
R2274 T3277 T3279 nsubjpass factor,implicated
R2275 T3278 T3279 auxpass is,implicated
R2276 T3279 T3279 ROOT implicated,implicated
R2277 T3280 T3279 prep in,implicated
R2278 T3113 T3111 cc or,Sox9
R2279 T3281 T3283 det all,phenotypes
R2280 T3282 T3283 amod other,phenotypes
R2281 T3283 T3280 pobj phenotypes,in
R2282 T3114 T3111 conj Sry,Sox9
R2283 T3284 T3279 punct .,implicated
R2284 T3285 T3322 prep Among,are
R2285 T3286 T3289 det the,proteins
R2286 T3115 T3109 prep in,Sox6
R2287 T3287 T3289 compound HMG,proteins
R2288 T3288 T3289 compound box,proteins
R2289 T3289 T3285 pobj proteins,Among
R2290 T3116 T3117 det the,extracts
R2291 T3290 T3291 advmod distantly,related
R2292 T3291 T3289 acl related,proteins
R2293 T3292 T3291 prep to,related
R2294 T3117 T3115 pobj extracts,in
R2295 T3293 T3292 pobj Sry,to
R2296 T3294 T3293 punct (,Sry
R2297 T3295 T3297 det the,member
R2298 T3118 T3095 conj restored,blocked
R2299 T3296 T3297 amod first,member
R2300 T3297 T3293 appos member,Sry
R2301 T3298 T3297 acl identified,member
R2302 T3119 T3118 dobj splicing,restored
R2303 T3299 T3298 prep of,identified
R2304 T3300 T3304 det the,family
R2305 T3314 T3308 conj bend,bind
R2306 T3301 T3303 compound Sox,factor
R2307 T3302 T3303 compound transcription,factor
R2308 T3303 T3304 compound factor,family
R2309 T3304 T3299 pobj family,of
R2310 T3315 T3314 dobj DNA,bend
R2311 T3305 T3293 punct ),Sry
R2312 T3306 T3308 nsubj that,bind
R2313 T3307 T3308 advmod similarly,bind
R2314 T3316 T3314 punct ",",bend
R2315 T3308 T3289 relcl bind,proteins
R2316 T3309 T3308 prep to,bind
R2317 T3310 T3312 det the,groove
R2318 T3311 T3312 amod minor,groove
R2319 T3312 T3309 pobj groove,to
R2320 T3313 T3308 cc and,bind
R2321 T3317 T3314 cc but,bend
R2322 T3318 T3308 prep without,bind
R2323 T3319 T3320 compound sequence,specificity
R2324 T3411 T3401 cc and,are
R2325 T3320 T3318 pobj specificity,without
R2326 T3412 T3401 conj function,are
R2327 T3413 T3415 nmod [,]
R2328 T3321 T3322 punct ",",are
R2329 T3414 T3415 nummod 22,]
R2330 T3415 T3412 dobj ],function
R2331 T3416 T3401 punct .,are
R2332 T3322 T3322 ROOT are,are
R2333 T3417 T3418 amod High-level,expression
R2334 T3418 T3422 nsubj expression,requires
R2335 T3419 T3418 prep of,expression
R2336 T3323 T3329 det the,proteins
R2337 T3420 T3421 det these,genes
R2338 T3421 T3419 pobj genes,of
R2339 T3422 T3422 ROOT requires,requires
R2340 T3324 T3325 nsubj ubiquitously,expressed
R2341 T3423 T3425 det a,element
R2342 T3424 T3425 amod regulatory,element
R2343 T3325 T3329 amod expressed,proteins
R2344 T3425 T3422 dobj element,requires
R2345 T3426 T3425 punct ",",element
R2346 T3326 T3329 nmod HMG1,proteins
R2347 T3427 T3430 det the,region
R2348 T3428 T3429 compound locus,control
R2349 T3327 T3326 cc and,HMG1
R2350 T3429 T3430 compound control,region
R2351 T3430 T3425 appos region,element
R2352 T3328 T3326 conj HMG2,HMG1
R2353 T3431 T3433 nsubjpass that,characterized
R2354 T3432 T3433 auxpass is,characterized
R2355 T3433 T3430 relcl characterized,region
R2356 T3329 T3322 attr proteins,are
R2357 T3330 T3332 nmod [,]
R2358 T3434 T3433 agent by,characterized
R2359 T3331 T3332 nummod 17,]
R2360 T3435 T3436 det a,set
R2361 T3436 T3434 pobj set,by
R2362 T3332 T3329 appos ],proteins
R2363 T3437 T3436 prep of,set
R2364 T3438 T3440 amod nuclease,sites
R2365 T3439 T3440 amod hypersensitive,sites
R2366 T3440 T3437 pobj sites,of
R2367 T3441 T3436 acl spread,set
R2368 T3442 T3441 prep over,spread
R2369 T3333 T3322 punct .,are
R2370 T3443 T3444 nummod 25,kb
R2371 T3444 T3445 npadvmod kb,located
R2372 T3445 T3436 acl located,set
R2373 T3334 T3345 nsubj Modulation,mediate
R2374 T3446 T3447 nummod 5,′
R2375 T3447 T3445 dobj ′,located
R2376 T3448 T3447 prep of,′
R2377 T3335 T3334 prep of,Modulation
R2378 T3449 T3451 det the,gene
R2379 T3450 T3451 amod ɛy,gene
R2380 T3451 T3448 pobj gene,of
R2381 T3336 T3337 compound DNA,structure
R2382 T3452 T3447 conj [,′
R2383 T3453 T3454 nummod 23,]
R2384 T3454 T3447 conj ],′
R2385 T3337 T3335 pobj structure,of
R2386 T3455 T3422 punct .,requires
R2387 T3456 T3458 det The,genes
R2388 T3457 T3458 amod β-globin,genes
R2389 T3338 T3334 agent by,Modulation
R2390 T3458 T3460 nsubjpass genes,expressed
R2391 T3459 T3460 auxpass are,expressed
R2392 T3460 T3460 ROOT expressed,expressed
R2393 T3339 T3343 det these,proteins
R2394 T3461 T3460 prep in,expressed
R2395 T3462 T3463 det a,tissue
R2396 T3463 T3461 pobj tissue,in
R2397 T3340 T3339 cc and,these
R2398 T3464 T3460 punct -,expressed
R2399 T3465 T3460 cc and,expressed
R2400 T3466 T3467 amod development-specific,fashion
R2401 T3341 T3343 amod other,proteins
R2402 T3467 T3460 conj fashion,expressed
R2403 T3468 T3460 punct .,expressed
R2404 T3469 T3473 prep In,originates
R2405 T3342 T3343 compound HMG,proteins
R2406 T3470 T3469 pobj mice,In
R2407 T3471 T3472 punct ",",erythropoiesis
R2408 T3472 T3473 nsubj erythropoiesis,originates
R2409 T3343 T3338 pobj proteins,by
R2410 T3473 T3473 ROOT originates,originates
R2411 T3474 T3473 prep in,originates
R2412 T3344 T3345 aux can,mediate
R2413 T3475 T3478 det the,sac
R2414 T3476 T3477 amod embryonic,yolk
R2415 T3477 T3478 compound yolk,sac
R2416 T3478 T3474 pobj sac,in
R2417 T3479 T3483 advmod where,express
R2418 T3480 T3482 amod primitive,cells
R2419 T3345 T3345 ROOT mediate,mediate
R2420 T3481 T3482 amod erythroid,cells
R2421 T3482 T3483 nsubj cells,express
R2422 T3483 T3478 relcl express,sac
R2423 T3346 T3348 amod long-range,function
R2424 T3484 T3483 dobj ɛy,express
R2425 T3485 T3484 cc and,ɛy
R2426 T3486 T3487 amod βh-1,globins
R2427 T3487 T3484 conj globins,ɛy
R2428 T3347 T3348 compound enhancer,function
R2429 T3488 T3490 nmod [,]
R2430 T3489 T3490 nummod 22,]
R2431 T3490 T3490 ROOT ],]
R2432 T3348 T3345 dobj function,mediate
R2433 T3491 T3490 punct .,]
R2434 T3492 T3523 prep At,]
R2435 T3493 T3502 nummod 11.5,shifts
R2436 T3349 T3348 prep on,function
R2437 T3494 T3502 nmod d,shifts
R2438 T3495 T3496 compound post,coitus
R2439 T3350 T3351 det both,DNA
R2440 T3496 T3502 dep coitus,shifts
R2441 T3497 T3498 punct (,dpc
R2442 T3498 T3496 parataxis dpc,coitus
R2443 T3351 T3349 pobj DNA,on
R2444 T3499 T3498 punct ),dpc
R2445 T3500 T3501 punct ",",erythropoiesis
R2446 T3501 T3502 compound erythropoiesis,shifts
R2447 T3352 T3351 cc and,DNA
R2448 T3502 T3492 pobj shifts,At
R2449 T3503 T3502 prep to,shifts
R2450 T3353 T3354 amod chromatin-assembled,genes
R2451 T3504 T3506 det the,liver
R2452 T3505 T3506 amod fetal,liver
R2453 T3354 T3351 conj genes,DNA
R2454 T3506 T3503 pobj liver,to
R2455 T3355 T3345 prep by,mediate
R2456 T3507 T3511 advmod where,express
R2457 T3356 T3355 pcomp bringing,by
R2458 T3357 T3356 advmod together,bringing
R2459 T3508 T3510 amod definitive,cells
R2460 T3358 T3359 amod distant,regions
R2461 T3509 T3510 amod erythroid,cells
R2462 T3510 T3511 nsubj cells,express
R2463 T3359 T3356 dobj regions,bringing
R2464 T3511 T3506 relcl express,liver
R2465 T3512 T3514 compound adult,globins
R2466 T3513 T3514 compound β,globins
R2467 T3514 T3511 dobj globins,express
R2468 T3515 T3514 punct (,globins
R2469 T3360 T3359 prep of,regions
R2470 T3516 T3517 advmod β,major
R2471 T3517 T3514 amod major,globins
R2472 T3518 T3517 cc and,major
R2473 T3361 T3360 pobj DNA,of
R2474 T3519 T3517 conj minor,major
R2475 T3520 T3492 punct ),At
R2476 T3521 T3523 nmod [,]
R2477 T3362 T3356 cc and,bringing
R2478 T3522 T3523 nummod 22,]
R2479 T3523 T3523 ROOT ],]
R2480 T3363 T3364 amod associated,factors
R2481 T3524 T3523 punct .,]
R2482 T3525 T3527 det The,gene
R2483 T3526 T3527 amod ɛy,gene
R2484 T3364 T3356 dobj factors,bringing
R2485 T3527 T3529 nsubjpass gene,silenced
R2486 T3528 T3529 auxpass is,silenced
R2487 T3365 T3345 punct .,mediate
R2488 T3529 T3529 ROOT silenced,silenced
R2489 T3530 T3529 prep in,silenced
R2490 T3531 T3533 amod definitive,cells
R2491 T3366 T3372 advmod Specifically,shown
R2492 T3532 T3533 amod erythroid,cells
R2493 T3533 T3530 pobj cells,in
R2494 T3367 T3372 punct ",",shown
R2495 T3534 T3529 punct .,silenced
R2496 T3535 T3536 det The,mechanism
R2497 T3536 T3549 nsubj mechanism,studied
R2498 T3368 T3369 compound HMG,proteins
R2499 T3537 T3536 prep of,mechanism
R2500 T3538 T3537 pcomp silencing,of
R2501 T3539 T3538 prep of,silencing
R2502 T3369 T3372 nsubjpass proteins,shown
R2503 T3540 T3542 poss its,counterpart
R2504 T3541 T3542 amod human,counterpart
R2505 T3542 T3539 pobj counterpart,of
R2506 T3370 T3372 aux have,shown
R2507 T3543 T3542 punct ",",counterpart
R2508 T3544 T3545 compound ɛ,globin
R2509 T3545 T3542 appos globin,counterpart
R2510 T3371 T3372 auxpass been,shown
R2511 T3546 T3549 punct ",",studied
R2512 T3547 T3549 aux has,studied
R2513 T3372 T3372 ROOT shown,shown
R2514 T3548 T3549 auxpass been,studied
R2515 T3549 T3549 ROOT studied,studied
R2516 T3550 T3549 advmod extensively,studied
R2517 T3551 T3549 punct .,studied
R2518 T3552 T3558 prep In,activated
R2519 T3553 T3554 amod definitive,erythropoiesis
R2520 T3554 T3552 pobj erythropoiesis,In
R2521 T3373 T3374 aux to,modulate
R2522 T3555 T3558 punct ",",activated
R2523 T3556 T3558 nsubjpass ɛ,activated
R2524 T3374 T3372 xcomp modulate,shown
R2525 T3557 T3558 auxpass is,activated
R2526 T3558 T3558 ROOT activated,activated
R2527 T3559 T3558 cc and,activated
R2528 T3375 T3376 amod β-globin,genes
R2529 T3560 T3558 conj silenced,activated
R2530 T3561 T3564 advmod autonomously,]
R2531 T3562 T3564 compound [,]
R2532 T3376 T3374 dobj genes,modulate
R2533 T3563 T3564 compound "24,25",]
R2534 T3564 T3560 dobj ],silenced
R2535 T3377 T3374 npadvmod [,modulate
R2536 T3565 T3560 punct ",",silenced
R2537 T3566 T3572 mark although,appears
R2538 T3567 T3572 prep in,appears
R2539 T3378 T3377 nummod 18,[
R2540 T3568 T3570 amod primitive,ɛ
R2541 T3569 T3570 compound erythropoiesis,ɛ
R2542 T3570 T3567 pobj ɛ,in
R2543 T3379 T3380 nummod 21,]
R2544 T3571 T3572 advmod also,appears
R2545 T3572 T3558 conj appears,activated
R2546 T3380 T3377 appos ],[
R2547 T3573 T3575 aux to,regulated
R2548 T3574 T3575 auxpass be,regulated
R2549 T3575 T3572 xcomp regulated,appears
R2550 T3381 T3372 punct .,shown
R2551 T3576 T3575 advmod competitively,regulated
R2552 T3577 T3579 nmod [,]
R2553 T3382 T3385 det The,genes
R2554 T3578 T3579 nummod 26,]
R2555 T3579 T3572 dep ],appears
R2556 T3580 T3572 punct .,appears
R2557 T3383 T3385 compound mouse,genes
R2558 T3581 T3582 det The,γ-globin
R2559 T3582 T3588 nsubjpass γ-globin,controlled
R2560 T3583 T3584 aux to,adult
R2561 T3384 T3385 compound β-globin,genes
R2562 T3385 T3395 nsubjpass genes,clustered
R2563 T3584 T3582 acl adult,γ-globin
R2564 T3585 T3586 compound β-globin,switch
R2565 T3386 T3385 appos ɛy,genes
R2566 T3586 T3588 nsubjpass switch,controlled
R2567 T3587 T3588 auxpass is,controlled
R2568 T3588 T3588 ROOT controlled,controlled
R2569 T3589 T3588 agent by,controlled
R2570 T3590 T3591 compound promoter,competition
R2571 T3591 T3589 pobj competition,by
R2572 T3387 T3386 punct ",",ɛy
R2573 T3592 T3591 prep for,competition
R2574 T3593 T3597 det the,]
R2575 T3388 T3386 appos βh1,ɛy
R2576 T3594 T3595 compound LCR,[
R2577 T3595 T3597 nmod [,]
R2578 T3389 T3386 punct ",",ɛy
R2579 T3596 T3597 nummod "24,25",]
R2580 T3597 T3592 pobj ],for
R2581 T3598 T3588 punct .,controlled
R2582 T3599 T3601 predet All,elements
R2583 T3390 T3386 conj β-major,ɛy
R2584 T3600 T3601 det the,elements
R2585 T3601 T3609 nsubj elements,are
R2586 T3391 T3390 punct ",",β-major
R2587 T3602 T3601 amod responsible,elements
R2588 T3603 T3602 prep for,responsible
R2589 T3604 T3603 pcomp silencing,for
R2590 T3392 T3390 cc and,β-major
R2591 T3393 T3390 conj β-minor,β-major
R2592 T3394 T3395 auxpass are,clustered
R2593 T3605 T3608 det the,gene
R2594 T3606 T3608 nmod ɛ,gene
R2595 T3395 T3395 ROOT clustered,clustered
R2596 T3607 T3608 compound globin,gene
R2597 T3608 T3604 dobj gene,silencing
R2598 T3396 T3395 prep on,clustered
R2599 T3609 T3609 ROOT are,are
R2600 T3610 T3609 prep within,are
R2601 T3611 T3613 det the,gene
R2602 T3397 T3396 pobj Chromosome,on
R2603 T3612 T3613 compound ɛ,gene
R2604 T3613 T3610 pobj gene,within
R2605 T3614 T3610 cc or,within
R2606 T3398 T3397 nummod 7,Chromosome
R2607 T3615 T3610 conj in,within
R2608 T3616 T3617 amod adjacent,sequences
R2609 T3399 T3395 cc and,clustered
R2610 T3617 T3615 pobj sequences,in
R2611 T3618 T3620 nmod [,]
R2612 T3400 T3401 nsubj they,are
R2613 T3619 T3620 nummod 27,]
R2614 T3620 T3609 attr ],are
R2615 T3621 T3609 punct ",",are
R2616 T3401 T3395 conj are,clustered
R2617 T3622 T3609 advcl suggesting,are
R2618 T3623 T3625 mark that,is
R2619 T3624 T3625 csubj silencing,is
R2620 T3625 T3622 ccomp is,suggesting
R2621 T3626 T3627 advmod primarily,gene
R2622 T3627 T3625 attr gene,is
R2623 T3402 T3403 advmod highly,homologous
R2624 T3628 T3627 amod autonomous,gene
R2625 T3629 T3609 punct .,are
R2626 T3630 T3654 csubj Using,identified
R2627 T3403 T3401 acomp homologous,are
R2628 T3631 T3632 compound promoter,deletion
R2629 T3632 T3633 compound deletion,analyses
R2630 T3633 T3630 dobj analyses,Using
R2631 T3404 T3403 prep to,homologous
R2632 T3634 T3633 prep in,analyses
R2633 T3635 T3637 amod transgenic,models
R2634 T3405 T3407 poss their,counterparts
R2635 T3636 T3637 compound mouse,models
R2636 T3637 T3634 pobj models,in
R2637 T3638 T3637 cc and,models
R2638 T3406 T3407 amod human,counterparts
R2639 T3639 T3640 compound cell,transfection
R2640 T3640 T3641 compound transfection,assays
R2641 T3641 T3637 conj assays,models
R2642 T3407 T3404 pobj counterparts,to
R2643 T3642 T3641 punct ",",assays
R2644 T3643 T3645 amod multiple,elements
R2645 T3408 T3407 prep in,counterparts
R2646 T3644 T3645 compound DNA,elements
R2647 T3645 T3641 conj elements,assays
R2648 T3646 T3645 amod important,elements
R2649 T3409 T3410 amod organizational,structure
R2650 T3647 T3646 prep to,important
R2651 T3648 T3650 det the,process
R2652 T3649 T3650 amod silencing,process
R2653 T3410 T3408 pobj structure,in
R2654 T3650 T3647 pobj process,to
R2655 T3651 T3654 aux have,identified
R2656 T3652 T3654 auxpass been,identified
R2657 T3702 T3688 punct ),shown
R2658 T3653 T3654 advmod previously,identified
R2659 T3654 T3654 ROOT identified,identified
R2660 T3655 T3654 prep in,identified
R2661 T3656 T3658 preconj both,proximal
R2662 T3703 T3704 aux to,regulate
R2663 T3657 T3658 det the,proximal
R2664 T3658 T3655 pobj proximal,in
R2665 T3659 T3658 cc and,proximal
R2666 T3704 T3688 advcl regulate,shown
R2667 T3660 T3664 det the,promoter
R2668 T3661 T3664 amod distal,promoter
R2669 T3662 T3664 compound ɛ,promoter
R2670 T3705 T3704 dobj ɛ,regulate
R2671 T3663 T3664 compound gene,promoter
R2672 T3664 T3658 conj promoter,proximal
R2673 T3665 T3667 nmod [,]
R2674 T3706 T3705 acl silencing,ɛ
R2675 T3666 T3667 nummod 27,]
R2676 T3667 T3664 appos ],promoter
R2677 T3707 T3709 nmod [,]
R2678 T3668 T3654 punct .,identified
R2679 T3669 T3672 poss Their,factors
R2680 T3670 T3672 amod corresponding,factors
R2681 T3708 T3709 nummod 27,]
R2682 T3671 T3672 compound transcription,factors
R2683 T3709 T3706 dobj ],silencing
R2684 T3672 T3686 nsubjpass factors,identified
R2685 T3673 T3672 punct ",",factors
R2686 T3674 T3675 amod such,as
R2687 T3710 T3686 punct .,identified
R2688 T3675 T3672 prep as,factors
R2689 T3676 T3675 pobj GATA-1,as
R269 T573 T575 nsubj Sox6,Silences
R2690 T3677 T3676 punct ",",GATA-1
R2691 T3711 T3714 advmod Thus,appears
R2692 T3678 T3676 conj YY-1,GATA-1
R2693 T3679 T3678 punct ",",YY-1
R2694 T3712 T3714 punct ",",appears
R2695 T3680 T3678 conj COUP-TF,YY-1
R2696 T3681 T3680 punct ",",COUP-TF
R2697 T3682 T3680 cc and,COUP-TF
R2698 T3713 T3714 nsubj it,appears
R2699 T3683 T3680 conj DRED,COUP-TF
R270 T574 T575 advmod Directly,Silences
R2700 T3684 T3686 aux have,identified
R2701 T3685 T3686 auxpass been,identified
R2702 T3714 T3714 ROOT appears,appears
R2703 T3686 T3686 ROOT identified,identified
R2704 T3687 T3686 cc and,identified
R2705 T3688 T3686 conj shown,identified
R2706 T3715 T3722 mark that,involves
R2707 T3689 T3691 aux to,bind
R2708 T3690 T3691 advmod directly,bind
R2709 T3691 T3688 xcomp bind,shown
R271 T575 T583 nsubj Silences,is
R2710 T3716 T3717 det the,silencing
R2711 T3692 T3691 prep to,bind
R2712 T3693 T3695 det these,elements
R2713 T3694 T3695 compound DNA,elements
R2714 T3717 T3722 nsubj silencing,involves
R2715 T3695 T3692 pobj elements,to
R2716 T3696 T3695 punct (,elements
R2717 T3697 T3688 prep as,shown
R2718 T3698 T3697 pobj part,as
R2719 T3699 T3698 prep of,part
R272 T576 T578 compound Epsilon,Expression
R2720 T3700 T3701 compound protein,complexes
R2721 T3718 T3717 prep of,silencing
R2722 T3701 T3699 pobj complexes,of
R2723 T3719 T3721 det the,gene
R2724 T3720 T3721 compound ɛ,gene
R2725 T3721 T3718 pobj gene,of
R2726 T3799 T3799 ROOT describe,describe
R2727 T3722 T3714 ccomp involves,appears
R2728 T3723 T3725 det a,network
R2729 T3800 T3803 mark that,exerts
R273 T577 T578 compound Globin,Expression
R2730 T3801 T3803 nsubj Sox6,exerts
R2731 T3724 T3725 amod complicated,network
R2732 T3802 T3803 advmod also,exerts
R2733 T3803 T3799 ccomp exerts,describe
R2734 T3725 T3722 dobj network,involves
R2735 T3804 T3805 amod pleiotropic,effects
R2736 T3805 T3803 dobj effects,exerts
R2737 T3726 T3725 prep of,network
R2738 T3806 T3805 prep on,effects
R2739 T3807 T3806 pobj erythropoiesis,on
R274 T578 T583 nsubj Expression,is
R2740 T3808 T3799 punct .,describe
R2741 T3727 T3729 amod multiple,elements
R2742 T3809 T3810 det These,effects
R2743 T3810 T3811 nsubj effects,include
R2744 T3728 T3729 compound cis,elements
R2745 T3811 T3811 ROOT include,include
R2746 T3812 T3813 amod delayed,maturation
R2747 T3813 T3811 dobj maturation,include
R2748 T3729 T3726 pobj elements,of
R2749 T3814 T3813 prep of,maturation
R275 T579 T578 prep in,Expression
R2750 T3815 T3814 pobj erythrocytes,of
R2751 T3816 T3819 punct (,enucleate
R2752 T3730 T3729 cc and,elements
R2753 T3817 T3819 nsubj that,enucleate
R2754 T3818 T3819 advmod normally,enucleate
R2755 T3731 T3732 amod transacting,proteins
R2756 T3819 T3813 appos enucleate,maturation
R2757 T3732 T3729 conj proteins,elements
R2758 T3820 T3819 advmod prior,enucleate
R2759 T3733 T3714 punct .,appears
R276 T580 T582 compound Definitive,Sox6
R2760 T3821 T3820 prep to,prior
R2761 T3822 T3821 pcomp entering,to
R2762 T3823 T3824 det the,bloodstream
R2763 T3734 T3767 prep In,shown
R2764 T3824 T3822 dobj bloodstream,entering
R2765 T3825 T3827 nmod [,]
R2766 T3826 T3827 nummod 27,]
R2767 T3735 T3734 pobj addition,In
R2768 T3827 T3824 appos ],bloodstream
R2769 T3828 T3827 punct ),]
R277 T581 T582 compound Erythropoiesis,Sox6
R2770 T3829 T3824 cc and,bloodstream
R2771 T3830 T3831 amod higher,expression
R2772 T3831 T3821 pobj expression,to
R2773 T3832 T3831 prep of,expression
R2774 T3736 T3735 prep to,addition
R2775 T3833 T3835 amod embryonic,genes
R2776 T3834 T3835 compound globin,genes
R2777 T3835 T3832 pobj genes,of
R2778 T3836 T3811 punct .,include
R2779 T3737 T3736 pcomp playing,to
R278 T582 T579 pobj Sox6,in
R2780 T3837 T3840 det The,effect
R2781 T3838 T3839 advmod most,extreme
R2782 T3738 T3740 det an,role
R2783 T3839 T3840 amod extreme,effect
R2784 T3840 T3841 nsubj effect,is
R2785 T3841 T3841 ROOT is,is
R2786 T3739 T3740 amod important,role
R2787 T3842 T3843 det the,persistence
R2788 T3843 T3841 attr persistence,is
R2789 T3844 T3843 prep of,persistence
R279 T583 T583 ROOT is,is
R2790 T3740 T3737 dobj role,playing
R2791 T3845 T3846 amod high,expression
R2792 T3846 T3844 pobj expression,of
R2793 T3847 T3846 prep of,expression
R2794 T3741 T3740 prep in,role
R2795 T3848 T3852 det the,gene
R2796 T3849 T3852 amod embryonic,gene
R2797 T3742 T3743 det the,development
R2798 T3850 T3852 compound ɛy,gene
R2799 T3851 T3852 compound globin,gene
R280 T584 T585 det a,member
R2800 T3852 T3847 pobj gene,of
R2801 T3743 T3741 pobj development,in
R2802 T3853 T3841 punct .,is
R2803 T3854 T3856 advmod Here,describe
R2804 T3855 T3856 nsubj we,describe
R2805 T3744 T3743 prep of,development
R2806 T3856 T3856 ROOT describe,describe
R2807 T3857 T3856 cc and,describe
R2808 T3745 T3748 det the,system
R2809 T3858 T3856 conj characterize,describe
R281 T585 T583 attr member,is
R2810 T3859 T3860 det the,effects
R2811 T3860 T3858 dobj effects,characterize
R2812 T3746 T3748 amod central,system
R2813 T3861 T3860 prep of,effects
R2814 T3862 T3861 pobj Sox6,of
R2815 T3863 T3860 prep on,effects
R2816 T3747 T3748 amod nervous,system
R2817 T3864 T3867 det the,gene
R2818 T3865 T3867 amod ɛy,gene
R2819 T3866 T3867 compound globin,gene
R282 T586 T585 prep of,member
R2820 T3867 T3863 pobj gene,on
R2821 T3868 T3856 punct .,describe
R2822 T3869 T3870 nsubj We,show
R2823 T3748 T3744 pobj system,of
R2824 T3870 T3870 ROOT show,show
R2825 T3871 T3882 mark that,represses
R2826 T3872 T3873 amod Sox6,binds
R2827 T3749 T3767 advcl [,shown
R2828 T3873 T3882 nsubj binds,represses
R2829 T3874 T3873 prep to,binds
R283 T587 T591 det the,family
R2830 T3875 T3877 det the,promoter
R2831 T3750 T3749 nummod 8,[
R2832 T3876 T3877 amod proximal,promoter
R2833 T3877 T3874 pobj promoter,to
R2834 T3878 T3877 prep of,promoter
R2835 T3751 T3752 nummod 11,]
R2836 T3879 T3880 amod ɛy,globin
R2837 T3880 T3878 pobj globin,of
R2838 T3881 T3877 cc and,promoter
R2839 T3752 T3749 appos ],[
R284 T588 T591 compound Sox,family
R2840 T3882 T3870 ccomp represses,show
R2841 T3883 T3884 poss its,transcription
R2842 T3884 T3882 dobj transcription,represses
R2843 T3753 T3752 punct ",",]
R2844 T3885 T3870 punct .,show
R2845 T3886 T3896 prep In,expressed
R2846 T3754 T3757 compound cartilage,]
R2847 T3887 T3891 nmod wild-type,mice
R2848 T3888 T3889 punct (,WT
R2849 T3889 T3887 appos WT,wild-type
R285 T589 T590 compound transcription,factor
R2850 T3755 T3757 compound [,]
R2851 T3890 T3889 punct ),WT
R2852 T3891 T3886 pobj mice,In
R2853 T3892 T3896 punct ",",expressed
R2854 T3756 T3757 compound "6,12,13",]
R2855 T3893 T3896 nsubjpass Sox6,expressed
R2856 T3894 T3896 auxpass is,expressed
R2857 T3895 T3896 neg not,expressed
R2858 T3757 T3749 conj ],[
R2859 T3758 T3757 punct ",",]
R286 T590 T591 compound factor,family
R2860 T3896 T3896 ROOT expressed,expressed
R2861 T3759 T3757 cc and,]
R2862 T3897 T3896 prep in,expressed
R2863 T3898 T3901 compound yolk,islands
R2864 T3760 T3763 compound muscle,]
R2865 T3761 T3763 compound [,]
R2866 T3899 T3901 compound sac,islands
R2867 T3900 T3901 compound blood,islands
R2868 T3762 T3763 compound "14,15",]
R2869 T3901 T3897 pobj islands,in
R287 T591 T586 pobj family,of
R2870 T3902 T3896 punct ",",expressed
R2871 T3903 T3896 cc but,expressed
R2872 T3904 T3905 auxpass is,expressed
R2873 T3905 T3896 conj expressed,expressed
R2874 T3906 T3905 prep in,expressed
R2875 T3763 T3757 conj ],]
R2876 T3907 T3908 amod fetal,liver
R2877 T3908 T3906 pobj liver,in
R2878 T3764 T3767 punct ",",shown
R2879 T3909 T3905 punct ",",expressed
R288 T592 T594 nsubjpass that,defined
R2880 T3910 T3913 det the,pattern
R2881 T3765 T3767 nsubjpass it,shown
R2882 T3911 T3913 amod opposite,pattern
R2883 T3912 T3913 compound expression,pattern
R2884 T3913 T3905 conj pattern,expressed
R2885 T3766 T3767 auxpass was,shown
R2886 T3914 T3913 prep of,pattern
R2887 T3915 T3916 amod ɛy,globin
R2888 T3767 T3767 ROOT shown,shown
R2889 T3916 T3914 pobj globin,of
R289 T593 T594 auxpass is,defined
R2890 T3917 T3896 punct .,expressed
R2891 T3918 T3928 prep In,expressed
R2892 T3768 T3770 mark that,is
R2893 T3919 T3920 det the,absence
R2894 T3920 T3918 pobj absence,In
R2895 T3921 T3920 prep of,absence
R2896 T3769 T3770 nsubj Sox6,is
R2897 T3922 T3921 pobj Sox6,of
R2898 T3923 T3928 punct ",",expressed
R2899 T3924 T3925 amod ɛy,globin
R290 T594 T585 relcl defined,member
R2900 T3770 T3767 ccomp is,shown
R2901 T3925 T3928 nsubjpass globin,expressed
R2902 T3926 T3928 auxpass is,expressed
R2903 T3771 T3770 acomp upregulated,is
R2904 T3927 T3928 advmod ectopically,expressed
R2905 T3928 T3928 ROOT expressed,expressed
R2906 T3929 T3928 prep in,expressed
R2907 T3772 T3771 prep in,upregulated
R2908 T3930 T3932 det the,liver
R2909 T3931 T3932 amod fetal,liver
R291 T595 T594 agent by,defined
R2910 T3932 T3929 pobj liver,in
R2911 T3773 T3776 amod long-term,cells
R2912 T3933 T3928 punct ",",expressed
R2913 T3934 T3928 advcl demonstrating,expressed
R2914 T3935 T3934 dobj that,demonstrating
R2915 T3774 T3776 compound hematopoiesis,cells
R2916 T3936 T3937 amod Sox6,functions
R2917 T3937 T3935 nsubj functions,that
R2918 T3775 T3776 compound stem,cells
R2919 T3938 T3937 prep in,functions
R292 T596 T600 det the,group
R2920 T3939 T3940 amod definitive,erythropoiesis
R2921 T3940 T3938 pobj erythropoiesis,in
R2922 T3941 T3928 punct .,expressed
R2923 T3776 T3772 pobj cells,in
R2924 T3777 T3778 punct (,LT-HSC
R2925 T3778 T3771 appos LT-HSC,upregulated
R2926 T3779 T3771 punct ),upregulated
R2927 T3780 T3771 prep compared,upregulated
R2928 T3781 T3780 prep with,compared
R2929 T3782 T3783 amod multipotent,progenitors
R293 T597 T600 amod conserved,group
R2933 T3783 T3781 pobj progenitors,with
R2934 T3784 T3783 prep of,progenitors
R2938 T3785 T3788 compound adult,marrow
R2939 T3786 T3788 compound mouse,marrow
R294 T598 T600 amod high,group
R2940 T3787 T3788 compound bone,marrow
R2941 T3788 T3789 compound marrow,lineage
R2943 T3789 T3784 pobj lineage,of
R2944 T3790 T3792 nmod [,]
R2945 T3791 T3792 nummod 28,]
R2946 T3792 T3783 appos ],progenitors
R2948 T3793 T3767 punct .,shown
R295 T599 T600 compound mobility,group
R2952 T3794 T3799 prep In,describe
R2953 T3795 T3796 det this,study
R2954 T3796 T3794 pobj study,In
R2956 T3797 T3799 punct ",",describe
R2957 T3798 T3799 nsubj we,describe
R296 T600 T595 pobj group,by
R297 T601 T602 punct (,HMG
R298 T602 T600 appos HMG,group
R299 T603 T602 punct ),HMG
R300 T604 T606 compound DNA,domain
R301 T605 T606 amod binding,domain
R302 T606 T600 conj domain,group
R303 T607 T606 punct ",",domain
R304 T608 T609 advmod first,described
R305 T609 T600 acl described,group
R306 T610 T609 prep in,described
R307 T611 T614 det the,gene
R308 T612 T614 amod testis,gene
R309 T613 T614 amod determining,gene
R310 T614 T610 pobj gene,in
R311 T615 T614 punct ",",gene
R312 T616 T614 appos Sry,gene
R313 T617 T583 punct .,is
R314 T618 T619 amod Previous,studies
R315 T619 T621 nsubj studies,suggested
R316 T620 T621 aux have,suggested
R317 T621 T621 ROOT suggested,suggested
R318 T622 T624 mark that,plays
R319 T623 T624 nsubj Sox6,plays
R320 T624 T621 ccomp plays,suggested
R321 T625 T626 det a,role
R322 T626 T624 dobj role,plays
R323 T627 T626 prep in,role
R324 T628 T629 det the,development
R325 T629 T627 pobj development,in
R326 T630 T629 prep of,development
R327 T631 T634 det the,system
R328 T632 T634 amod central,system
R329 T633 T634 amod nervous,system
R330 T634 T630 pobj system,of
R331 T635 T634 punct ",",system
R332 T636 T634 conj cartilage,system
R333 T637 T636 punct ",",cartilage
R334 T638 T636 cc and,cartilage
R335 T639 T636 conj muscle,cartilage
R336 T640 T621 punct .,suggested
R337 T641 T652 prep In,expressed
R338 T642 T644 det the,mouse
R339 T643 T644 amod Sox6-deficient,mouse
R340 T644 T641 pobj mouse,In
R341 T645 T652 punct ",",expressed
R342 T646 T652 nsubjpass p100H,expressed
R343 T647 T652 punct ",",expressed
R344 T648 T649 amod ɛy,globin
R345 T649 T652 nsubjpass globin,expressed
R346 T650 T652 auxpass is,expressed
R347 T651 T652 advmod persistently,expressed
R348 T652 T652 ROOT expressed,expressed
R349 T653 T652 punct ",",expressed
R3495 T4964 T4965 amod Persistent,Expression
R3496 T4965 T4965 ROOT Expression,Expression
R3497 T4966 T4965 prep of,Expression
R3498 T4967 T4969 det the,Globin
R3499 T4968 T4969 compound Embryonic,Globin
R350 T654 T652 cc and,expressed
R3500 T4969 T4966 pobj Globin,of
R3501 T4970 T4969 punct ",",Globin
R3502 T4971 T4965 intj ɛy,Expression
R3503 T4972 T4965 punct ",",Expression
R3504 T4973 T4965 prep in,Expression
R3505 T4974 T4975 amod Sox6-Deficient,Mice
R3506 T4975 T4973 pobj Mice,in
R3507 T4976 T4979 det The,gene
R3508 T4977 T4979 amod ɛy,gene
R3509 T4978 T4979 compound globin,gene
R351 T655 T656 amod increased,numbers
R3510 T4979 T4982 nsubjpass gene,identified
R3511 T4980 T4982 auxpass was,identified
R3512 T4981 T4982 advmod initially,identified
R3513 T4982 T4982 ROOT identified,identified
R3514 T4983 T4982 prep as,identified
R3515 T4984 T4986 det an,transcript
R3516 T4985 T4986 amod upregulated,transcript
R3517 T4986 T4983 pobj transcript,as
R3518 T4987 T4986 prep in,transcript
R3519 T4988 T4990 det the,mouse
R352 T656 T661 nsubj numbers,are
R3520 T4989 T4990 amod p 100H,mouse
R3521 T4990 T4987 pobj mouse,in
R3522 T4991 T4986 acl using,transcript
R3523 T4992 T4993 amod subtractive,hybridization
R3524 T4993 T4991 dobj hybridization,using
R3525 T4994 T4995 aux to,identify
R3526 T4995 T4991 xcomp identify,using
R3527 T4996 T4998 amod Sox6,targets
R3528 T4997 T4998 amod downstream,targets
R3529 T4998 T4995 dobj targets,identify
R353 T657 T656 prep of,numbers
R3530 T4999 T4982 punct .,identified
R3531 T5000 T5002 det This,observation
R3532 T5001 T5002 amod initial,observation
R3533 T5002 T5004 nsubjpass observation,confirmed
R3534 T5003 T5004 auxpass was,confirmed
R3535 T5004 T5004 ROOT confirmed,confirmed
R3536 T5005 T5004 prep in,confirmed
R3537 T5006 T5009 det an,allele
R3538 T5007 T5009 amod independent,allele
R3539 T5008 T5009 amod knock-out,allele
R354 T658 T660 amod nucleated,cells
R3540 T5009 T5005 pobj allele,in
R3541 T5010 T5009 prep of,allele
R3542 T5011 T5012 compound Sox6,[
R3543 T5012 T5010 pobj [,of
R3544 T5013 T5014 nummod 13,]
R3545 T5014 T5009 appos ],allele
R3546 T5015 T5004 advcl using,confirmed
R3547 T5016 T5019 amod real-time,reaction
R3548 T5017 T5019 compound polymerase,reaction
R3549 T5018 T5019 compound chain,reaction
R355 T659 T660 amod red,cells
R3550 T5019 T5015 dobj reaction,using
R3551 T5020 T5019 punct (,reaction
R3552 T5021 T5019 appos PCR,reaction
R3553 T5022 T5019 punct ),reaction
R3554 T5023 T5019 punct (,reaction
R3555 T5024 T5025 amod unpublished,data
R3556 T5025 T5019 appos data,reaction
R3557 T5026 T5019 punct ),reaction
R3558 T5027 T5004 punct .,confirmed
R3559 T5028 T5029 compound Real-time,PCR
R356 T660 T657 pobj cells,of
R3560 T5029 T5031 nsubjpass PCR,used
R3561 T5030 T5031 auxpass was,used
R3562 T5031 T5031 ROOT used,used
R3563 T5032 T5033 aux to,quantitate
R3564 T5033 T5031 xcomp quantitate,used
R3565 T5034 T5036 det the,levels
R3566 T5035 T5036 compound expression,levels
R3567 T5036 T5033 dobj levels,quantitate
R3568 T5037 T5036 prep of,levels
R3569 T5038 T5040 amod other,genes
R357 T661 T652 conj are,expressed
R3570 T5039 T5040 compound globin,genes
R3571 T5040 T5037 pobj genes,of
R3572 T5041 T5040 prep in,genes
R3573 T5042 T5043 amod p100H,mutant
R3574 T5043 T5047 amod mutant,livers
R3575 T5044 T5043 cc and,mutant
R3576 T5045 T5047 compound WT,livers
R3577 T5046 T5047 compound mouse,livers
R3578 T5047 T5041 pobj livers,in
R3579 T5048 T5033 prep at,quantitate
R358 T662 T661 acomp present,are
R3580 T5049 T5051 nummod two,stages
R3581 T5050 T5051 amod developmental,stages
R3582 T5051 T5048 pobj stages,at
R3583 T5052 T5051 punct ",",stages
R3584 T5053 T5057 nummod 15.5,dpc
R3585 T5054 T5057 nmod dpc,dpc
R3586 T5055 T5054 cc and,dpc
R3587 T5056 T5057 nummod 18.5,dpc
R3588 T5057 T5051 appos dpc,stages
R3589 T5058 T5031 punct .,used
R359 T663 T662 prep in,present
R3590 T5059 T5060 mark As,shown
R3591 T5060 T5069 advcl shown,expressed
R3592 T5061 T5060 prep in,shown
R3593 T5062 T5061 pobj Figure,in
R3594 T5063 T5062 nummod 1,Figure
R3595 T5064 T5069 punct ",",expressed
R3596 T5065 T5067 det the,gene
R3597 T5066 T5067 amod ɛy,gene
R3598 T5067 T5069 nsubjpass gene,expressed
R3599 T5068 T5069 auxpass is,expressed
R360 T664 T666 det the,circulation
R3600 T5069 T5069 ROOT expressed,expressed
R3601 T5070 T5069 prep at,expressed
R3602 T5071 T5072 amod high,levels
R3603 T5072 T5070 pobj levels,at
R3604 T5073 T5072 prep at,levels
R3605 T5074 T5075 det both,time
R3606 T5075 T5076 compound time,points
R3607 T5076 T5073 pobj points,at
R3608 T5077 T5072 prep in,levels
R3609 T5078 T5079 amod mutant,mice
R361 T665 T666 amod fetal,circulation
R3610 T5079 T5077 pobj mice,in
R3611 T5080 T5069 punct ",",expressed
R3612 T5081 T5069 prep in,expressed
R3613 T5082 T5081 pobj contrast,in
R3614 T5083 T5082 prep to,contrast
R3615 T5084 T5085 det the,decline
R3616 T5085 T5083 pobj decline,to
R3617 T5086 T5085 prep in,decline
R3618 T5087 T5086 pobj expression,in
R3619 T5088 T5085 acl observed,decline
R362 T666 T663 pobj circulation,in
R3620 T5089 T5088 prep in,observed
R3621 T5090 T5091 compound WT,mice
R3622 T5091 T5089 pobj mice,in
R3623 T5092 T5069 punct .,expressed
R3624 T5093 T5094 det No,difference
R3625 T5094 T5096 nsubjpass difference,seen
R3626 T5095 T5096 auxpass was,seen
R3627 T5096 T5096 ROOT seen,seen
R3628 T5097 T5096 prep between,seen
R3629 T5098 T5101 nmod WT,mice
R363 T667 T661 punct .,are
R3630 T5099 T5098 cc and,WT
R3631 T5100 T5098 conj heterozygous,WT
R3632 T5101 T5097 pobj mice,between
R3633 T5102 T5104 punct (,data
R3634 T5103 T5104 amod unpublished,data
R3635 T5104 T5101 appos data,mice
R3636 T5105 T5101 punct ),mice
R3637 T5106 T5096 punct .,seen
R3638 T5107 T5124 advmod Interestingly,are
R3639 T5108 T5124 punct ",",are
R364 T668 T669 compound Transfection,assays
R3640 T5109 T5111 det the,levels
R3641 T5110 T5111 compound expression,levels
R3642 T5111 T5124 nsubj levels,are
R3643 T5112 T5111 prep of,levels
R3644 T5113 T5118 det the,genes
R3645 T5114 T5118 amod other,genes
R3646 T5115 T5118 nummod two,genes
R3647 T5116 T5118 amod embryonic,genes
R3648 T5117 T5118 compound globin,genes
R3649 T5118 T5112 pobj genes,of
R365 T669 T676 nsubj assays,define
R3650 T5119 T5118 punct (,genes
R3651 T5120 T5118 appos ζ,genes
R3652 T5121 T5120 cc and,ζ
R3653 T5122 T5120 conj βh1,ζ
R3654 T5123 T5118 punct ),genes
R3655 T5124 T5124 ROOT are,are
R3656 T5125 T5124 advmod also,are
R3657 T5126 T5124 acomp higher,are
R3658 T5127 T5126 prep in,higher
R3659 T5128 T5130 amod p100H,mice
R366 T670 T669 prep in,assays
R3660 T5129 T5130 amod homozygous,mice
R3661 T5130 T5127 pobj mice,in
R3662 T5131 T5124 punct ",",are
R3663 T5132 T5124 prep compared,are
R3664 T5133 T5132 prep with,compared
R3665 T5134 T5135 compound WT,mice
R3666 T5135 T5133 pobj mice,with
R3667 T5136 T5124 punct ",",are
R3668 T5137 T5124 cc but,are
R3669 T5138 T5144 prep to,seen
R367 T671 T670 pobj GM979,in
R3670 T5139 T5142 det a,extent
R3671 T5140 T5141 advmod much,lesser
R3672 T5141 T5142 amod lesser,extent
R3673 T5142 T5138 pobj extent,to
R3674 T5143 T5144 mark than,seen
R3675 T5144 T5124 conj seen,are
R3676 T5145 T5144 prep for,seen
R3677 T5146 T5147 amod ɛy,globin
R3678 T5147 T5145 pobj globin,for
R3679 T5148 T5144 prep at,seen
R368 T672 T673 punct (,erythroleukemic
R3680 T5149 T5150 nummod 18.5,dpc
R3681 T5150 T5148 pobj dpc,at
R3682 T5151 T5152 punct (,Figure
R3683 T5152 T5144 conj Figure,seen
R3684 T5153 T5152 nummod 1,Figure
R3685 T5154 T5152 punct ),Figure
R3686 T5155 T5124 punct .,are
R3687 T5156 T5165 advmod Moreover,is
R3688 T5157 T5165 punct ",",is
R3689 T5158 T5160 det the,level
R369 T673 T671 appos erythroleukemic,GM979
R3690 T5159 T5160 compound expression,level
R3691 T5160 T5165 nsubj level,is
R3692 T5161 T5160 prep of,level
R3693 T5162 T5164 amod adult,globin
R3694 T5163 T5164 compound β,globin
R3695 T5164 T5161 pobj globin,of
R3696 T5165 T5165 ROOT is,is
R3697 T5166 T5165 advmod also,is
R3698 T5167 T5168 advmod somewhat,higher
R3699 T5168 T5165 acomp higher,is
R370 T674 T673 punct ),erythroleukemic
R3700 T5169 T5168 prep in,higher
R3701 T5170 T5172 amod p100H,mice
R3702 T5171 T5172 amod homozygous,mice
R3703 T5172 T5169 pobj mice,in
R3704 T5173 T5168 prep than,higher
R3705 T5174 T5173 prep in,than
R3706 T5175 T5176 compound WT,mice
R3707 T5176 T5174 pobj mice,in
R3708 T5177 T5165 prep at,is
R3709 T5178 T5179 nummod 18.5,dpc
R371 T675 T676 nsubj cells,define
R3710 T5179 T5177 pobj dpc,at
R3711 T5180 T5181 punct (,Figure
R3712 T5181 T5165 npadvmod Figure,is
R3713 T5182 T5181 nummod 1,Figure
R3714 T5183 T5181 punct ),Figure
R3715 T5184 T5165 punct .,is
R3716 T5185 T5186 amod Perinatal,lethality
R3717 T5186 T5200 nsubj lethality,precludes
R3718 T5187 T5186 prep of,lethality
R3719 T5188 T5189 amod mutant,mice
R372 T676 T676 ROOT define,define
R3720 T5189 T5187 pobj mice,of
R3721 T5190 T5192 punct (,from
R3722 T5191 T5192 advmod presumably,from
R3723 T5192 T5186 prep from,lethality
R3724 T5193 T5195 det the,defect
R3725 T5194 T5195 compound heart,defect
R3726 T5195 T5192 pobj defect,from
R3727 T5196 T5200 nsubj [,precludes
R3728 T5197 T5198 nummod 14,]
R3729 T5198 T5196 appos ],[
R373 T677 T681 det a,region
R3730 T5199 T5196 punct ),[
R3731 T5200 T5200 ROOT precludes,precludes
R3732 T5201 T5200 dobj us,precludes
R3733 T5202 T5200 prep from,precludes
R3734 T5203 T5202 pcomp evaluating,from
R3735 T5204 T5206 amod postnatal,expression
R3736 T5205 T5206 compound globin,expression
R3737 T5206 T5203 dobj expression,evaluating
R3738 T5207 T5200 punct .,precludes
R3739 T5208 T5209 det The,graphs
R374 T678 T681 nummod 36,region
R3740 T5209 T5213 nsubj graphs,illustrate
R3741 T5210 T5209 prep in,graphs
R3742 T5211 T5210 pobj Figure,in
R3743 T5212 T5211 nummod 1,Figure
R3744 T5213 T5213 ROOT illustrate,illustrate
R3745 T5214 T5215 amod real,time
R3746 T5215 T5217 compound time,results
R3747 T5216 T5217 compound PCR,results
R3748 T5217 T5213 dobj results,illustrate
R3749 T5218 T5220 nsubjpass that,performed
R375 T679 T681 compound base,region
R3750 T5219 T5220 auxpass were,performed
R3751 T5220 T5217 relcl performed,results
R3752 T5221 T5220 prep in,performed
R3753 T5222 T5221 pobj triplicate,in
R3754 T5223 T5222 punct (,triplicate
R3755 T5224 T5225 amod standard,deviation
R3756 T5225 T5230 nsubjpass deviation,shown
R3757 T5226 T5225 prep of,deviation
R3758 T5227 T5228 det the,data
R3759 T5228 T5226 pobj data,of
R376 T680 T681 compound pair,region
R3760 T5229 T5230 auxpass is,shown
R3761 T5230 T5213 ccomp shown,illustrate
R3762 T5231 T5230 agent by,shown
R3763 T5232 T5233 compound error,bars
R3764 T5233 T5231 pobj bars,by
R3765 T5234 T5230 punct ),shown
R3766 T5235 T5213 punct .,illustrate
R3767 T5236 T5242 mark Because,performed
R3768 T5237 T5242 nsubjpass all,performed
R3769 T5238 T5237 prep of,all
R377 T681 T676 dobj region,define
R3770 T5239 T5240 det the,assays
R3771 T5240 T5238 pobj assays,of
R3772 T5241 T5242 auxpass were,performed
R3773 T5242 T5256 advcl performed,are
R3774 T5243 T5242 prep at,performed
R3775 T5244 T5246 det the,time
R3776 T5245 T5246 amod same,time
R3777 T5246 T5243 pobj time,at
R3778 T5247 T5242 prep with,performed
R3779 T5248 T5251 det the,control
R378 T682 T681 prep of,region
R3780 T5249 T5251 amod same,control
R3781 T5250 T5251 amod internal,control
R3782 T5251 T5247 pobj control,with
R3783 T5252 T5256 punct ",",are
R3784 T5253 T5254 det the,levels
R3785 T5254 T5256 nsubj levels,are
R3786 T5255 T5254 acl shown,levels
R3787 T5256 T5256 ROOT are,are
R3788 T5257 T5258 amod relative,levels
R3789 T5258 T5256 attr levels,are
R379 T683 T686 det the,promoter
R3790 T5259 T5256 cc and,are
R3791 T5260 T5256 conj are,are
R3792 T5261 T5262 advmod thus,comparable
R3793 T5262 T5260 acomp comparable,are
R3794 T5263 T5260 prep across,are
R3795 T5264 T5265 det all,samples
R3796 T5265 T5263 pobj samples,across
R3797 T5266 T5260 cc and,are
R3798 T5267 T5260 conj are,are
R3799 T5268 T5267 prep in,are
R380 T684 T686 amod ɛy,promoter
R3800 T5269 T5268 pobj agreement,in
R3801 T5270 T5269 prep with,agreement
R3802 T5271 T5272 advmod previously,published
R3803 T5272 T5273 amod published,results
R3804 T5273 T5270 pobj results,with
R3805 T5274 T5273 prep for,results
R3806 T5275 T5277 nmod WT,mice
R3807 T5276 T5277 amod fetal,mice
R3808 T5277 T5274 pobj mice,for
R3809 T5278 T5280 nmod [,]
R381 T685 T686 amod proximal,promoter
R3810 T5279 T5280 nummod 29,]
R3811 T5280 T5277 appos ],mice
R3812 T5281 T5256 punct .,are
R3813 T5282 T5283 nsubj We,note
R3814 T5283 T5283 ROOT note,note
R3815 T5284 T5302 mark that,is
R3816 T5285 T5286 det the,level
R3817 T5286 T5302 nsubj level,is
R3818 T5287 T5286 prep of,level
R3819 T5288 T5289 amod ɛy,expression
R382 T686 T682 pobj promoter,of
R3820 T5289 T5287 pobj expression,of
R3821 T5290 T5286 prep in,level
R3822 T5291 T5292 det the,livers
R3823 T5292 T5290 pobj livers,in
R3824 T5293 T5292 prep of,livers
R3825 T5294 T5301 nummod 15.5,mice
R3826 T5295 T5301 nmod dpc,mice
R3827 T5296 T5295 cc and,dpc
R3828 T5297 T5298 nummod 18.5,dpc
R3829 T5298 T5301 nmod dpc,mice
R383 T687 T688 nsubj that,is
R3830 T5299 T5301 amod homozygous,mice
R3831 T5300 T5301 amod mutant,mice
R3832 T5301 T5293 pobj mice,of
R3833 T5302 T5283 ccomp is,note
R3834 T5303 T5304 advmod statistically,equivalent
R3835 T5304 T5302 acomp equivalent,is
R3836 T5305 T5304 prep to,equivalent
R3837 T5306 T5307 det the,level
R3838 T5307 T5305 pobj level,to
R3839 T5308 T5307 prep of,level
R384 T688 T686 relcl is,promoter
R3840 T5309 T5312 compound βmaj,expression
R3841 T5310 T5312 compound /,expression
R3842 T5311 T5312 compound min,expression
R3843 T5312 T5308 pobj expression,of
R3844 T5313 T5307 prep in,level
R3845 T5314 T5315 det the,livers
R3846 T5315 T5313 pobj livers,in
R3847 T5316 T5315 prep of,livers
R3848 T5317 T5324 nummod 15.5,mice
R3849 T5318 T5324 nmod dpc,mice
R385 T689 T688 acomp critical,is
R3850 T5319 T5318 cc and,dpc
R3851 T5320 T5321 nummod 18.5,dpc
R3852 T5321 T5324 nmod dpc,mice
R3853 T5322 T5324 amod homozygous,mice
R3854 T5323 T5324 compound WT,mice
R3855 T5324 T5316 pobj mice,of
R3856 T5325 T5283 punct .,note
R386 T690 T689 prep for,critical
R387 T691 T693 amod Sox6,repression
R388 T692 T693 amod mediated,repression
R389 T693 T690 pobj repression,for
R390 T694 T676 punct .,define
R391 T695 T698 amod Electrophoretic,assay
R392 T696 T698 compound mobility,assay
R393 T697 T698 compound shift,assay
R394 T698 T708 nmod assay,assays
R395 T699 T700 punct (,EMSA
R396 T700 T698 appos EMSA,assay
R397 T701 T700 punct ),EMSA
R398 T702 T698 cc and,assay
R399 T703 T704 compound chromatin,immunoprecipitation
R400 T704 T698 conj immunoprecipitation,assay
R401 T705 T704 punct (,immunoprecipitation
R402 T706 T704 appos ChIP,immunoprecipitation
R403 T707 T704 punct ),immunoprecipitation
R404 T708 T709 nsubj assays,demonstrate
R405 T709 T709 ROOT demonstrate,demonstrate
R406 T710 T718 mark that,binding
R407 T711 T712 amod Sox6,acts
R408 T712 T718 nsubj acts,binding
R409 T713 T712 prep as,acts
R410 T714 T715 det a,repressor
R411 T715 T713 pobj repressor,as
R412 T716 T712 prep by,acts
R413 T717 T718 advmod directly,binding
R414 T718 T709 ccomp binding,demonstrate
R415 T719 T718 prep to,binding
R4426 T6363 T6364 compound Transfection,Studies
R4427 T6364 T6365 compound Studies,Using
R4428 T6365 T6365 ROOT Using,Using
R4429 T6366 T6368 compound GM979,Indicate
R4430 T6367 T6368 compound Cells,Indicate
R4431 T6368 T6365 dobj Indicate,Using
R4432 T6369 T6365 nsubj That,Using
R4433 T6370 T6372 nsubj Sox6,Represses
R4434 T6371 T6372 advmod Directly,Represses
R4435 T6372 T6369 nsubj Represses,That
R4436 T6373 T6374 det the,ɛy
R4437 T6374 T6376 compound ɛy,Promoter
R4438 T6375 T6376 compound Gene,Promoter
R4439 T6376 T6372 dobj Promoter,Represses
R4440 T6377 T6376 prep at,Promoter
R4441 T6378 T6383 det the,assays
R4442 T6379 T6380 compound Transcriptional,Level
R4443 T6380 T6383 nmod Level,assays
R4444 T6381 T6383 amod Real-time,assays
R4445 T6382 T6383 compound PCR,assays
R4446 T6383 T6377 pobj assays,at
R4447 T6384 T6383 punct (,assays
R4448 T6385 T6383 appos Figure,assays
R4449 T6386 T6385 nummod 1,Figure
R4450 T6387 T6385 punct ),Figure
R4451 T6388 T6397 nmod measure,activity
R4452 T6389 T6390 amod steady-state,levels
R4453 T6390 T6388 dobj levels,measure
R4454 T6391 T6390 prep of,levels
R4455 T6392 T6393 compound ɛy,mRNA
R4456 T6393 T6391 pobj mRNA,of
R4457 T6394 T6393 punct ",",mRNA
R4458 T6395 T6397 neg not,activity
R4459 T6396 T6397 amod transcriptional,activity
R4460 T6397 T6383 appos activity,assays
R4461 T6398 T6397 prep of,activity
R4462 T6399 T6401 det the,promoter
R4463 T6400 T6401 amod ɛy,promoter
R4464 T6401 T6398 pobj promoter,of
R4465 T6402 T6365 punct .,Using
R4466 T6403 T6404 aux To,investigate
R4467 T6404 T6420 advcl investigate,used
R4468 T6405 T6408 mark whether,acts
R4469 T6406 T6408 nsubj Sox6,acts
R4470 T6407 T6408 advmod directly,acts
R4471 T6408 T6404 ccomp acts,investigate
R4472 T6409 T6408 prep on,acts
R4473 T6410 T6413 det the,promoter
R4474 T6411 T6413 amod ɛy,promoter
R4475 T6412 T6413 compound gene,promoter
R4476 T6413 T6409 pobj promoter,on
R4477 T6414 T6413 prep at,promoter
R4478 T6415 T6417 det the,level
R4479 T6416 T6417 amod transcriptional,level
R4480 T6417 T6414 pobj level,at
R4481 T6418 T6420 punct ",",used
R4482 T6419 T6420 nsubj we,used
R4483 T6420 T6420 ROOT used,used
R4484 T6421 T6426 det an,assay
R4485 T6422 T6426 nmod in,assay
R4486 T6423 T6426 amod vitro,assay
R4487 T6424 T6426 nmod transient,assay
R4488 T6425 T6426 compound transfection,assay
R4489 T6426 T6420 dobj assay,used
R4490 T6427 T6426 cc and,assay
R4491 T6428 T6429 compound GM979,cells
R4492 T6429 T6426 conj cells,assay
R4493 T6430 T6420 punct ",",used
R4494 T6431 T6435 det a,line
R4495 T6432 T6435 amod murine,line
R4496 T6433 T6435 amod erythroleukemic,line
R4497 T6434 T6435 compound cell,line
R4498 T6435 T6420 dobj line,used
R4499 T6436 T6437 nsubj that,expresses
R4500 T6437 T6435 relcl expresses,line
R4501 T6438 T6439 det both,ɛy
R4502 T6439 T6437 dobj ɛy,expresses
R4503 T6440 T6439 cc and,ɛy
R4504 T6441 T6443 amod adult,globins
R4505 T6442 T6443 compound beta,globins
R4506 T6443 T6446 dep globins,]
R4507 T6444 T6446 nmod [,]
R4508 T6445 T6446 nummod 30,]
R4509 T6446 T6439 conj ],ɛy
R4510 T6447 T6420 punct .,used
R4511 T6448 T6449 nsubj We,generated
R4512 T6449 T6449 ROOT generated,generated
R4513 T6450 T6453 det an,reporter
R4514 T6451 T6453 amod ɛy,reporter
R4515 T6452 T6453 compound promoter,reporter
R4516 T6453 T6454 nsubj reporter,construct
R4517 T6454 T6449 ccomp construct,generated
R4518 T6455 T6456 punct (,E-Luc
R4519 T6456 T6454 dep E-Luc,construct
R4520 T6457 T6456 punct ),E-Luc
R4521 T6458 T6454 prep by,construct
R4522 T6459 T6458 pcomp fusing,by
R4523 T6460 T6461 det a,micro-LCR
R4524 T6461 T6459 dobj micro-LCR,fusing
R4525 T6462 T6463 punct (,μLCR
R4526 T6463 T6461 appos μLCR,micro-LCR
R4527 T6464 T6463 punct ),μLCR
R4528 T6465 T6461 conj element,micro-LCR
R4529 T6466 T6465 punct (,element
R4530 T6467 T6468 nummod 2.5,kb
R4531 T6468 T6465 appos kb,element
R4532 T6469 T6465 punct ),element
R4533 T6470 T6472 nmod [,]
R4534 T6471 T6472 nummod 31,]
R4535 T6472 T6461 appos ],micro-LCR
R4536 T6473 T6459 prep to,fusing
R4537 T6474 T6477 det the,promoter
R4538 T6475 T6477 amod ɛy,promoter
R4539 T6476 T6477 amod proximal,promoter
R4540 T6477 T6473 pobj promoter,to
R4541 T6478 T6477 punct (,promoter
R4542 T6479 T6480 nummod 2.2,kb
R4543 T6480 T6477 appos kb,promoter
R4544 T6481 T6477 punct ),promoter
R4545 T6482 T6459 punct ",",fusing
R4546 T6483 T6454 advcl followed,construct
R4547 T6484 T6483 agent by,followed
R4548 T6485 T6488 det the,gene
R4549 T6486 T6488 compound luciferase,gene
R4550 T6487 T6488 compound reporter,gene
R4551 T6488 T6484 pobj gene,by
R4552 T6489 T6483 punct ",",followed
R4553 T6490 T6491 mark as,shown
R4554 T6491 T6454 advcl shown,construct
R4555 T6492 T6491 prep in,shown
R4556 T6493 T6492 pobj Figure,in
R4557 T6494 T6493 nummod 2A,Figure
R4558 T6495 T6496 punct (,detailed
R4559 T6496 T6454 advcl detailed,construct
R4560 T6497 T6496 prep in,detailed
R4561 T6498 T6497 pobj Materials,in
R4562 T6499 T6498 cc and,Materials
R4563 T6500 T6498 conj Methods,Materials
R4564 T6501 T6496 punct ),detailed
R4565 T6502 T6449 punct .,generated
R4566 T6503 T6512 nsubj Overexpression,leads
R4567 T6504 T6503 prep of,Overexpression
R4568 T6505 T6504 pobj Sox6,of
R4569 T6506 T6503 prep in,Overexpression
R4570 T6507 T6508 compound GM979,cells
R4571 T6508 T6506 pobj cells,in
R4572 T6509 T6503 agent by,Overexpression
R4573 T6510 T6511 amod transient,transfection
R4574 T6511 T6509 pobj transfection,by
R4575 T6512 T6512 ROOT leads,leads
R4576 T6513 T6512 prep to,leads
R4577 T6514 T6516 det a,repression
R4578 T6515 T6516 amod dosage-dependent,repression
R4579 T6516 T6513 pobj repression,to
R4580 T6517 T6516 prep of,repression
R4581 T6518 T6520 amod E-Luc,activity
R4582 T6519 T6520 compound reporter,activity
R4583 T6520 T6517 pobj activity,of
R4584 T6521 T6523 punct (,2B
R4585 T6522 T6523 compound Figure,2B
R4586 T6523 T6520 appos 2B,activity
R4587 T6524 T6520 punct ),activity
R4588 T6525 T6512 punct .,leads
R4589 T6526 T6551 prep In,fails
R4590 T6527 T6526 pobj contrast,In
R4591 T6528 T6551 punct ",",fails
R4592 T6529 T6551 nsubj overexpression,fails
R4593 T6530 T6529 prep of,overexpression
R4594 T6531 T6534 det a,protein
R4595 T6532 T6534 amod truncated,protein
R4596 T6533 T6534 compound Sox6,protein
R4597 T6534 T6530 pobj protein,of
R4598 T6535 T6536 nsubj that,lacks
R4599 T6536 T6534 relcl lacks,protein
R4600 T6537 T6539 poss its,domain
R4601 T6538 T6539 compound HMG,domain
R4602 T6539 T6536 dobj domain,lacks
R4603 T6540 T6542 nmod [,]
R4604 T6541 T6542 nummod 32,]
R4605 T6542 T6539 appos ],domain
R4606 T6543 T6542 punct (,]
R4607 T6544 T6542 amod similar,]
R4608 T6545 T6544 prep to,similar
R4609 T6546 T6549 det the,allele
R4610 T6547 T6549 amod p 100H,allele
R4611 T6548 T6549 compound mouse,allele
R4612 T6549 T6545 pobj allele,to
R4613 T6550 T6542 punct ),]
R4614 T6551 T6551 ROOT fails,fails
R4615 T6552 T6553 aux to,repress
R4616 T6553 T6551 xcomp repress,fails
R4617 T6554 T6555 amod E-Luc,activity
R4618 T6555 T6553 dobj activity,repress
R4619 T6556 T6558 punct (,2B
R4620 T6557 T6558 compound Figure,2B
R4621 T6558 T6555 appos 2B,activity
R4622 T6559 T6558 punct ),2B
R4623 T6560 T6551 punct .,fails
R4624 T6561 T6562 det These,data
R4625 T6562 T6563 nsubj data,indicate
R4626 T6563 T6563 ROOT indicate,indicate
R4627 T6564 T6568 mark that,repress
R4628 T6565 T6566 amod Sox6,acts
R4629 T6566 T6568 nsubj acts,repress
R4630 T6567 T6568 aux to,repress
R4631 T6568 T6563 ccomp repress,indicate
R4632 T6569 T6571 det the,promoter
R4633 T6570 T6571 amod ɛy,promoter
R4634 T6571 T6568 dobj promoter,repress
R4635 T6572 T6571 prep at,promoter
R4636 T6573 T6575 det the,level
R4637 T6574 T6575 amod transcriptional,level
R4638 T6575 T6572 pobj level,at
R4639 T6576 T6563 punct .,indicate
R4640 T6577 T6580 nsubjpass Sox6,shown
R4641 T6578 T6580 aux has,shown
R4642 T6579 T6580 auxpass been,shown
R4643 T6580 T6580 ROOT shown,shown
R4644 T6581 T6582 aux to,act
R4645 T6582 T6580 xcomp act,shown
R4646 T6583 T6582 prep as,act
R4647 T6584 T6585 det a,repressor
R4648 T6585 T6583 pobj repressor,as
R4649 T6586 T6582 cc and,act
R4650 T6587 T6588 aux to,interact
R4651 T6588 T6582 conj interact,act
R4652 T6589 T6588 prep with,interact
R4653 T6590 T6593 det a,co-repressor
R4654 T6591 T6592 advmod widely,expressed
R4655 T6592 T6593 amod expressed,co-repressor
R4656 T6593 T6589 pobj co-repressor,with
R4657 T6594 T6593 punct ",",co-repressor
R4658 T6595 T6593 appos CtBP2,co-repressor
R4659 T6596 T6588 punct ",",interact
R4660 T6597 T6588 prep on,interact
R4661 T6598 T6600 det the,promoter
R4662 T6599 T6600 amod fgf-3,promoter
R4663 T6600 T6597 pobj promoter,on
R4664 T6601 T6603 nmod [,]
R4665 T6602 T6601 nummod 5,[
R4666 T6603 T6600 appos ],promoter
R4667 T6604 T6580 punct .,shown
R4668 T6605 T6607 nsubjpass CtBP2,expressed
R4669 T6606 T6607 auxpass is,expressed
R4670 T6607 T6607 ROOT expressed,expressed
R4671 T6608 T6607 prep in,expressed
R4672 T6609 T6610 compound GM979,cells
R4673 T6610 T6608 pobj cells,in
R4674 T6611 T6613 punct (,data
R4675 T6612 T6613 amod unpublished,data
R4676 T6613 T6610 appos data,cells
R4677 T6614 T6607 punct ),expressed
R4678 T6615 T6607 punct .,expressed
R4679 T6616 T6617 aux To,investigate
R4680 T6617 T6634 advcl investigate,introduced
R4681 T6618 T6624 mark whether,required
R4682 T6619 T6620 det the,interaction
R4683 T6620 T6624 nsubjpass interaction,required
R4684 T6621 T6620 prep with,interaction
R4685 T6622 T6621 pobj CtBP2,with
R4686 T6623 T6624 auxpass is,required
R4687 T6624 T6617 ccomp required,investigate
R4688 T6625 T6624 prep for,required
R4689 T6626 T6627 amod Sox6,repression
R4690 T6627 T6625 pobj repression,for
R4691 T6628 T6627 prep of,repression
R4692 T6629 T6631 det the,promoter
R4693 T6630 T6631 amod ɛy,promoter
R4694 T6631 T6628 pobj promoter,of
R4695 T6632 T6634 punct ",",introduced
R4696 T6633 T6634 nsubj we,introduced
R4697 T6634 T6634 ROOT introduced,introduced
R4698 T6635 T6637 det a,mutation
R4699 T6636 T6637 compound point,mutation
R4700 T6637 T6634 dobj mutation,introduced
R4701 T6638 T6637 punct (,mutation
R4702 T6639 T6637 appos L386H,mutation
R4703 T6640 T6637 punct ),mutation
R4704 T6641 T6634 prep in,introduced
R4705 T6642 T6644 det the,protein
R4706 T6643 T6644 amod Sox6,protein
R4707 T6644 T6641 pobj protein,in
R4708 T6645 T6649 nsubjpass that,reported
R4709 T6646 T6649 aux has,reported
R4710 T6647 T6649 auxpass been,reported
R4711 T6648 T6649 advmod previously,reported
R4712 T6649 T6644 relcl reported,protein
R4713 T6650 T6651 aux to,be
R4714 T6651 T6649 xcomp be,reported
R4715 T6652 T6651 acomp sufficient,be
R4716 T6653 T6654 aux to,abolish
R4717 T6654 T6652 xcomp abolish,sufficient
R4718 T6655 T6656 amod Sox6-CtBP2,interaction
R4719 T6656 T6654 dobj interaction,abolish
R4720 T6657 T6659 nmod [,]
R4721 T6658 T6657 nummod 5,[
R4722 T6659 T6644 appos ],protein
R4723 T6660 T6634 punct .,introduced
R4724 T6661 T6664 det This,change
R4725 T6662 T6664 amod amino,change
R4726 T6663 T6664 compound acid,change
R4727 T6664 T6665 nsubj change,is
R4728 T6665 T6665 ROOT is,is
R4729 T6666 T6665 neg not,is
R4730 T6667 T6665 prep in,is
R4731 T6668 T6672 det the,domain
R4732 T6669 T6670 compound HMG,DNA
R4733 T6670 T6672 compound DNA,domain
R4734 T6671 T6672 amod binding,domain
R4735 T6672 T6667 pobj domain,in
R4736 T6673 T6665 punct .,is
R4737 T6674 T6681 advmod However,retains
R4738 T6675 T6681 punct ",",retains
R4739 T6676 T6678 det this,version
R4740 T6677 T6678 amod mutant,version
R4741 T6678 T6681 nsubj version,retains
R4742 T6679 T6678 prep of,version
R4743 T6680 T6679 pobj Sox6,of
R4744 T6681 T6681 ROOT retains,retains
R4745 T6682 T6683 det the,ability
R4746 T6683 T6681 dobj ability,retains
R4747 T6684 T6685 aux to,repress
R4748 T6685 T6683 acl repress,ability
R4749 T6686 T6688 det the,promoter
R4750 T6687 T6688 amod ɛy,promoter
R4751 T6688 T6685 dobj promoter,repress
R4752 T6689 T6688 prep in,promoter
R4753 T6690 T6692 det the,assay
R4754 T6691 T6692 compound transfection,assay
R4755 T6692 T6689 pobj assay,in
R4756 T6693 T6695 punct (,2B
R4757 T6694 T6695 compound Figure,2B
R4758 T6695 T6692 appos 2B,assay
R4759 T6696 T6692 punct ),assay
R4760 T6697 T6681 punct ",",retains
R4761 T6698 T6681 advcl indicating,retains
R4762 T6699 T6701 mark that,represses
R4763 T6700 T6701 nsubj Sox6,represses
R4764 T6701 T6698 ccomp represses,indicating
R4765 T6702 T6704 det the,promoter
R4766 T6703 T6704 amod ɛy,promoter
R4767 T6704 T6701 dobj promoter,represses
R4768 T6705 T6704 prep in,promoter
R4769 T6706 T6708 det a,manner
R4770 T6707 T6708 amod CtBP2-independent,manner
R4771 T6708 T6705 pobj manner,in
R4772 T6709 T6681 punct .,retains
R4773 T6710 T6711 compound Deletion,analysis
R4774 T6711 T6723 nsubj analysis,defined
R4775 T6712 T6711 prep of,analysis
R4776 T6713 T6715 det the,promoter
R4777 T6714 T6715 amod ɛy,promoter
R4778 T6715 T6712 pobj promoter,of
R4779 T6716 T6711 punct ",",analysis
R4780 T6717 T6718 mark as,shown
R4781 T6718 T6711 advcl shown,analysis
R4782 T6719 T6718 prep in,shown
R4783 T6720 T6719 pobj Figure,in
R4784 T6721 T6720 nummod 2C,Figure
R4785 T6722 T6723 punct ",",defined
R4786 T6723 T6723 ROOT defined,defined
R4787 T6724 T6725 det a,region
R4788 T6725 T6723 dobj region,defined
R4789 T6726 T6727 punct (,−
R4790 T6727 T6728 amod −,63
R4791 T6728 T6723 npadvmod 63,defined
R4792 T6729 T6728 prep to,63
R4793 T6730 T6729 pobj −,to
R4794 T6731 T6730 appos 37,−
R4795 T6732 T6730 punct ),−
R4796 T6733 T6729 prep within,to
R4797 T6734 T6737 det the,promoter
R4798 T6735 T6737 amod ɛy,promoter
R4799 T6736 T6737 amod proximal,promoter
R4800 T6737 T6733 pobj promoter,within
R4801 T6738 T6739 nsubj that,is
R4802 T6739 T6737 relcl is,promoter
R4803 T6740 T6739 acomp critical,is
R4804 T6741 T6740 prep for,critical
R4805 T6742 T6743 amod Sox6,repression
R4806 T6743 T6741 pobj repression,for
R4807 T6744 T6723 punct .,defined
R4808 T6745 T6750 nsubj Analysis,reveals
R4809 T6746 T6745 prep of,Analysis
R4810 T6747 T6749 det this,region
R4811 T6748 T6749 amod short,region
R4812 T6749 T6746 pobj region,of
R4813 T6750 T6750 ROOT reveals,reveals
R4814 T6751 T6755 nummod two,sites
R4815 T6752 T6755 amod Sox/Sox6,sites
R4816 T6753 T6755 nmod consensus,sites
R4817 T6754 T6755 amod binding,sites
R4818 T6755 T6750 dobj sites,reveals
R4819 T6756 T6758 nmod [,]
R4820 T6757 T6758 nummod 5,]
R4821 T6758 T6761 compound ],3A
R4822 T6759 T6760 punct (,Figure
R4823 T6760 T6761 compound Figure,3A
R4824 T6761 T6750 oprd 3A,reveals
R4825 T6762 T6750 punct ),reveals
R4826 T6763 T6750 punct .,reveals
R488 T720 T722 det the,promoter
R489 T721 T722 amod ɛy,promoter
R490 T722 T719 pobj promoter,to
R491 T723 T709 punct .,demonstrate
R492 T724 T726 det The,expression
R493 T725 T726 amod normal,expression
R494 T726 T744 nsubj expression,demonstrate
R495 T727 T726 prep of,expression
R496 T728 T727 pobj Sox6,of
R497 T729 T726 prep in,expression
R498 T730 T732 amod wild-type,liver
R499 T731 T732 amod fetal,liver
R500 T732 T729 pobj liver,in
R501 T733 T732 cc and,liver
R502 T734 T736 det the,expression
R503 T735 T736 amod ectopic,expression
R504 T736 T732 conj expression,liver
R505 T737 T736 prep of,expression
R506 T738 T737 pobj ɛy,of
R507 T739 T738 prep in,ɛy
R508 T740 T743 amod p100H,liver
R509 T741 T743 amod homozygous,liver
R510 T742 T743 amod fetal,liver
R511 T743 T739 pobj liver,in
R512 T744 T744 ROOT demonstrate,demonstrate
R513 T745 T744 dobj that,demonstrate
R514 T746 T747 amod Sox6,functions
R515 T747 T745 conj functions,that
R516 T748 T747 prep in,functions
R517 T749 T750 amod definitive,erythropoiesis
R518 T750 T748 pobj erythropoiesis,in
R519 T751 T744 punct .,demonstrate
R520 T752 T754 det The,study
R521 T753 T754 amod present,study
R522 T754 T755 nsubj study,shows
R523 T755 T755 ROOT shows,shows
R524 T756 T759 mark that,required
R525 T757 T759 nsubjpass Sox6,required
R526 T758 T759 auxpass is,required
R527 T759 T755 ccomp required,shows
R528 T760 T759 prep for,required
R529 T761 T760 pcomp silencing,for
R530 T762 T761 prep of,silencing
R531 T763 T764 amod ɛy,globin
R532 T764 T762 pobj globin,of
R533 T765 T761 prep in,silencing
R534 T766 T767 amod definitive,erythropoiesis
R535 T767 T765 pobj erythropoiesis,in
R536 T768 T759 cc and,required
R537 T769 T755 conj suggests,shows
R538 T770 T771 det a,role
R539 T771 T769 dobj role,suggests
R540 T772 T771 prep for,role
R541 T773 T772 pobj Sox6,for
R542 T774 T771 prep in,role
R543 T775 T777 amod erythroid,maturation
R544 T776 T777 compound cell,maturation
R545 T777 T774 pobj maturation,in
R546 T778 T755 punct .,shows
R547 T779 T787 advmod Thus,provide
R548 T780 T787 punct ",",provide
R549 T781 T782 amod Sox6,regulation
R550 T782 T787 nsubj regulation,provide
R551 T783 T782 prep of,regulation
R552 T784 T785 amod ɛy,globin
R553 T785 T783 pobj globin,of
R554 T786 T787 aux might,provide
R555 T787 T787 ROOT provide,provide
R556 T788 T789 det a,novel
R557 T789 T787 dobj novel,provide
R558 T790 T791 amod therapeutical,target
R559 T791 T789 appos target,novel
R560 T792 T787 prep in,provide
R5604 T8230 T8230 ROOT corresponds,corresponds
R5605 T8231 T8230 prep to,corresponds
R5606 T8232 T8234 det the,region
R5607 T8233 T8234 amod critical,region
R5608 T8234 T8231 pobj region,to
R5609 T8140 T8155 nsubj EMSA,repress
R561 T793 T794 det the,treatment
R5610 T8141 T8140 cc and,EMSA
R5611 T8142 T8144 compound ChIP,Show
R5612 T8235 T8234 prep of,region
R5613 T8143 T8144 compound Assays,Show
R5614 T8144 T8140 conj Show,EMSA
R5615 T8145 T8148 mark that,Binds
R5616 T8236 T8238 det the,promoter
R5617 T8146 T8148 nsubj Sox6,Binds
R5618 T8147 T8148 advmod Directly,Binds
R5619 T8148 T8155 advcl Binds,repress
R562 T794 T792 pobj treatment,in
R5620 T8149 T8148 prep to,Binds
R5621 T8237 T8238 amod ɛy,promoter
R5622 T8150 T8151 det the,ɛy
R5623 T8151 T8155 nsubj ɛy,repress
R5624 T8152 T8153 compound Promoter,Sox6
R5625 T8153 T8151 appos Sox6,ɛy
R5626 T8238 T8235 pobj promoter,of
R5627 T8154 T8155 aux might,repress
R5628 T8155 T8155 ROOT repress,repress
R5629 T8239 T8238 acl defined,promoter
R563 T795 T794 prep of,treatment
R5630 T8156 T8158 det the,promoter
R5631 T8157 T8158 amod ɛy,promoter
R5632 T8158 T8155 dobj promoter,repress
R5633 T8240 T8239 prep in,defined
R5634 T8159 T8155 punct ",",repress
R5635 T8160 T8161 preconj either,through
R5636 T8161 T8155 prep through,repress
R5637 T8162 T8164 amod direct,contact
R5638 T8241 T8244 poss our,analyses
R5639 T8163 T8164 amod physical,contact
R564 T796 T795 pobj hemoglobinopathies,of
R5640 T8164 T8161 pobj contact,through
R5641 T8165 T8164 prep with,contact
R5642 T8242 T8243 compound promoter,deletion
R5643 T8166 T8167 det the,promoter
R5644 T8167 T8165 pobj promoter,with
R5645 T8168 T8165 cc or,with
R5646 T8243 T8244 compound deletion,analyses
R5647 T8169 T8155 prep by,repress
R5648 T8170 T8169 pcomp regulating,by
R5649 T8171 T8170 dobj intermediates,regulating
R565 T797 T798 amod such,as
R5650 T8244 T8240 pobj analyses,in
R5651 T8172 T8171 acl affecting,intermediates
R5652 T8173 T8175 det the,promoter
R5653 T8245 T8230 punct .,corresponds
R5654 T8174 T8175 amod ɛy,promoter
R5655 T8175 T8172 dobj promoter,affecting
R5656 T8176 T8155 punct .,repress
R5657 T8177 T8178 aux To,investigate
R5658 T8178 T8191 advcl investigate,performed
R5659 T8179 T8183 mark whether,associated
R566 T798 T796 prep as,hemoglobinopathies
R5660 T8180 T8183 nsubjpass Sox6,associated
R5661 T8181 T8183 auxpass is,associated
R5662 T8246 T8247 det This,probe
R5663 T8182 T8183 advmod directly,associated
R5664 T8183 T8178 ccomp associated,investigate
R5665 T8184 T8183 prep with,associated
R5666 T8185 T8187 det the,promoter
R5667 T8247 T8248 nsubj probe,contains
R5668 T8186 T8187 amod ɛy,promoter
R5669 T8187 T8184 pobj promoter,with
R567 T799 T800 compound sickle,cell
R5670 T8188 T8191 punct ",",performed
R5671 T8189 T8191 nsubj we,performed
R5672 T8248 T8248 ROOT contains,contains
R5673 T8190 T8191 advmod first,performed
R5674 T8191 T8191 ROOT performed,performed
R5675 T8192 T8194 amod electrophoretic,shift
R5676 T8193 T8194 compound mobility,shift
R5677 T8194 T8195 compound shift,assays
R5678 T8195 T8191 dobj assays,performed
R5679 T8249 T8253 nummod two,sites
R568 T800 T801 compound cell,anemia
R5680 T8196 T8195 punct (,assays
R5681 T8197 T8195 appos EMSA,assays
R5682 T8198 T8195 punct ),assays
R5683 T8199 T8191 advcl using,performed
R5684 T8200 T8202 det a,Sox6
R5685 T8250 T8253 compound consensus,sites
R5686 T8201 T8202 amod c-Myc-tagged,Sox6
R5687 T8251 T8253 nmod Sox/Sox6,sites
R5688 T8202 T8199 dobj Sox6,using
R5689 T8203 T8199 prep in,using
R569 T801 T798 pobj anemia,as
R5690 T8204 T8207 det a,transcription/translation
R5691 T8252 T8253 amod binding,sites
R5692 T8205 T8207 nmod reticulocyte,transcription/translation
R5693 T8206 T8207 amod lysate-based,transcription/translation
R5694 T8207 T8203 pobj transcription/translation,in
R5695 T8253 T8248 dobj sites,contains
R5696 T8208 T8207 prep in,transcription/translation
R5697 T8209 T8210 amod vitro,system
R5698 T8254 T8248 punct .,contains
R5699 T8210 T8208 pobj system,in
R570 T802 T801 cc and,anemia
R5700 T8211 T8191 punct .,performed
R5701 T8255 T8256 advmod Also,included
R5702 T8212 T8213 det The,probes
R5703 T8213 T8216 nsubjpass probes,listed
R5704 T8214 T8213 acl used,probes
R5705 T8215 T8216 auxpass are,listed
R5706 T8216 T8216 ROOT listed,listed
R5707 T8217 T8216 prep in,listed
R5708 T8256 T8256 ROOT included,included
R5709 T8218 T8219 compound Figure,3A
R571 T803 T801 conj thalassemia,anemia
R5710 T8219 T8217 pobj 3A,in
R5711 T8220 T8216 punct .,listed
R5712 T8257 T8256 prep in,included
R5713 T8221 T8224 det The,pair
R5714 T8222 T8223 nummod 36,base
R5715 T8223 T8224 compound base,pair
R5716 T8258 T8259 poss our,EMSA
R5717 T8224 T8224 ROOT pair,pair
R5718 T8225 T8224 punct (,pair
R5719 T8226 T8224 appos bp,pair
R572 T804 T787 punct .,provide
R5720 T8259 T8257 pobj EMSA,in
R5721 T8227 T8224 punct ),pair
R5722 T8228 T8229 compound WT,probe
R5723 T8229 T8230 nsubj probe,corresponds
R5724 T8260 T8256 auxpass are,included
R5725 T8261 T8263 nummod three,probes
R5726 T8262 T8263 amod mutated,probes
R5727 T8263 T8256 nsubjpass probes,included
R5728 T8327 T8323 pobj protein,by
R5729 T8264 T8265 nsubj that,are
R5730 T8328 T8322 punct .,shifted
R5731 T8329 T8336 advmod Moreover,supershift
R5732 T8330 T8336 punct ",",supershift
R5733 T8265 T8263 relcl are,probes
R5734 T8331 T8332 preconj both,c-Myc
R5735 T8332 T8336 nsubj c-Myc,supershift
R5736 T8266 T8265 punct ",",are
R5737 T8333 T8332 cc and,c-Myc
R5738 T8334 T8332 conj Sox6,c-Myc
R5739 T8335 T8332 conj antibodies,c-Myc
R5740 T8267 T8268 preconj either,truncated
R5741 T8336 T8336 ROOT supershift,supershift
R5742 T8337 T8338 det the,band
R5743 T8268 T8265 acomp truncated,are
R5744 T8338 T8336 dobj band,supershift
R5745 T8339 T8336 punct ",",supershift
R5746 T8340 T8336 advcl indicating,supershift
R5747 T8269 T8268 punct (,truncated
R5748 T8341 T8344 mark that,is
R5749 T8342 T8343 det the,binding
R5750 T8343 T8344 nsubj binding,is
R5751 T8270 T8268 npadvmod M1,truncated
R5752 T8344 T8340 ccomp is,indicating
R5753 T8345 T8344 acomp Sox6-specific,is
R5754 T8346 T8336 punct .,supershift
R5755 T8347 T8348 aux To,rule
R5756 T8348 T8366 advcl rule,used
R5757 T8349 T8348 prt out,rule
R5758 T8271 T8268 punct ),truncated
R5759 T8350 T8351 det the,possibility
R5760 T8351 T8348 dobj possibility,rule
R5761 T8352 T8357 mark that,binds
R5762 T8272 T8265 punct ",",are
R5763 T8353 T8355 det the,tag
R5764 T8354 T8355 amod c-Myc,tag
R5765 T8355 T8357 nsubj tag,binds
R5766 T8273 T8265 cc or,are
R5767 T8356 T8355 appos itself,tag
R5768 T8357 T8351 acl binds,possibility
R5769 T8274 T8265 conj mutated,are
R5770 T8275 T8274 punct (,mutated
R5771 T8358 T8357 prep to,binds
R5772 T8276 T8274 dobj M2,mutated
R5773 T8359 T8360 det the,probe
R5774 T8360 T8358 pobj probe,to
R5775 T8361 T8366 punct ",",used
R5776 T8277 T8276 cc and,M2
R5777 T8362 T8364 det an,Sox6
R5778 T8363 T8364 amod HA-tagged,Sox6
R5779 T8364 T8366 nsubjpass Sox6,used
R5780 T8278 T8276 conj M3,M2
R5781 T8365 T8366 auxpass was,used
R5782 T8366 T8366 ROOT used,used
R5783 T8279 T8276 punct ),M2
R5784 T8367 T8366 prep in,used
R5785 T8368 T8369 det another,EMSA
R5786 T8369 T8367 pobj EMSA,in
R5787 T8280 T8274 prep in,mutated
R5788 T8370 T8371 nsubj that,confirmed
R5789 T8371 T8366 ccomp confirmed,used
R5790 T8372 T8373 det these,results
R5791 T8281 T8280 pobj Sox/Sox6,in
R5792 T8373 T8371 dobj results,confirmed
R5793 T8374 T8376 punct (,3C
R5794 T8375 T8376 compound Figure,3C
R5795 T8282 T8283 amod binding,sites
R5796 T8376 T8373 appos 3C,results
R5797 T8377 T8376 punct ),3C
R5798 T8378 T8366 punct .,used
R5799 T8283 T8280 pobj sites,in
R5800 T8379 T8382 advmod Next,extracts
R5801 T8380 T8382 punct ",",extracts
R5802 T8284 T8286 punct (,3A
R5803 T8381 T8382 amod nuclear,extracts
R5804 T8382 T8387 nsubjpass extracts,used
R5805 T8383 T8382 prep from,extracts
R5806 T8384 T8385 compound MEL,cells
R5807 T8385 T8383 pobj cells,from
R5808 T8386 T8387 auxpass were,used
R5809 T8387 T8387 ROOT used,used
R5810 T8285 T8286 compound Figure,3A
R5811 T8388 T8387 prep in,used
R5812 T8389 T8388 pobj EMSA,in
R5813 T8390 T8387 advcl employing,used
R5814 T8286 T8274 npadvmod 3A,mutated
R5815 T8391 T8394 det the,probe
R5816 T8392 T8394 amod same,probe
R5817 T8393 T8394 amod 36-bp,probe
R5818 T8287 T8263 punct ),probes
R5819 T8394 T8390 dobj probe,employing
R5820 T8395 T8387 punct .,used
R5821 T8396 T8397 compound MEL,cells
R5822 T8288 T8256 punct .,included
R5823 T8397 T8397 ROOT cells,cells
R5824 T8398 T8397 punct ",",cells
R5825 T8399 T8403 det a,line
R5826 T8289 T8290 nsubj Sox6,is
R5827 T8400 T8403 amod murine,line
R5828 T8401 T8402 compound erythroleukemic,cell
R5829 T8402 T8403 compound cell,line
R5830 T8290 T8290 ROOT is,is
R5831 T8403 T8397 appos line,cells
R5832 T8404 T8403 punct ",",line
R5833 T8405 T8408 amod express,globins
R5834 T8291 T8290 acomp able,is
R5835 T8406 T8408 compound adult,globins
R5836 T8407 T8408 compound β,globins
R5837 T8408 T8403 conj globins,line
R5838 T8292 T8294 aux to,associate
R5839 T8409 T8408 punct ",",globins
R5840 T8410 T8408 cc but,globins
R5841 T8411 T8412 neg not,ɛy
R5842 T8293 T8294 advmod physically,associate
R5843 T8412 T8408 conj ɛy,globins
R5844 T8413 T8415 nmod [,]
R5845 T8414 T8415 nummod 33,]
R5846 T8294 T8291 xcomp associate,able
R5847 T8415 T8415 ROOT ],]
R5848 T8416 T8415 punct .,]
R5849 T8417 T8419 amod Sox6,binds
R5850 T8295 T8294 prep with,associate
R5851 T8418 T8419 advmod directly,binds
R5852 T8419 T8419 ROOT binds,binds
R5853 T8420 T8419 prep to,binds
R5854 T8296 T8298 det the,region
R5855 T8421 T8423 det this,sequence
R5856 T8422 T8423 compound DNA,sequence
R5857 T8423 T8420 pobj sequence,to
R5858 T8297 T8298 amod 36-bp,region
R5859 T8298 T8295 pobj region,with
R5860 T8424 T8423 prep in,sequence
R5861 T8299 T8301 punct (,3B
R5862 T8300 T8301 compound Figure,3B
R5863 T8425 T8426 compound MEL,cells
R5864 T8301 T8298 appos 3B,region
R5865 T8426 T8424 pobj cells,in
R5866 T8302 T8298 punct ),region
R5867 T8427 T8428 punct (,Figure
R5868 T8428 T8426 appos Figure,cells
R5869 T8303 T8294 prep within,associate
R5870 T8429 T8428 nummod 3D,Figure
R5871 T8430 T8428 punct ),Figure
R5872 T8431 T8419 punct .,binds
R5873 T8304 T8306 det the,promoter
R5874 T8432 T8434 det The,consensus
R5875 T8433 T8434 amod intact,consensus
R5876 T8434 T8434 ROOT consensus,consensus
R5877 T8305 T8306 amod ɛy,promoter
R5878 T8435 T8434 appos Sox/Sox6,consensus
R5879 T8306 T8303 pobj promoter,within
R5880 T8436 T8437 amod binding,sites
R5881 T8307 T8306 acl defined,promoter
R5882 T8437 T8443 nsubjpass sites,required
R5883 T8438 T8437 prep of,sites
R5884 T8308 T8307 agent by,defined
R5885 T8439 T8441 det the,probe
R5886 T8440 T8441 compound DNA,probe
R5887 T8309 T8312 det the,experiments
R5888 T8441 T8438 pobj probe,of
R5889 T8442 T8443 auxpass are,required
R5890 T8443 T8434 relcl required,consensus
R5891 T8310 T8312 compound deletion,experiments
R5892 T8444 T8443 prep for,required
R5893 T8445 T8446 det the,binding
R5894 T8311 T8312 compound analysis,experiments
R5895 T8446 T8444 pobj binding,for
R5896 T8447 T8443 punct ",",required
R5897 T8312 T8308 pobj experiments,by
R5898 T8448 T8449 mark as,shown
R5899 T8449 T8443 advcl shown,required
R5900 T8450 T8449 prep in,shown
R5901 T8313 T8314 punct (,Figure
R5902 T8451 T8453 det the,assay
R5903 T8452 T8453 compound competition,assay
R5904 T8314 T8312 appos Figure,experiments
R5905 T8453 T8450 pobj assay,in
R5906 T8454 T8455 punct (,Figure
R5907 T8455 T8453 appos Figure,assay
R5908 T8456 T8455 nummod 3E,Figure
R5909 T8457 T8455 punct ),Figure
R5910 T8458 T8443 punct .,required
R5911 T8459 T8470 nsubj Ablation,abolish
R5912 T8315 T8314 nummod 2C,Figure
R5913 T8460 T8459 prep of,Ablation
R5914 T8461 T8464 amod putative,sites
R5915 T8462 T8464 nmod Sox/Sox6,sites
R5916 T8316 T8314 punct ),Figure
R5917 T8463 T8464 amod binding,sites
R5918 T8464 T8460 pobj sites,of
R5919 T8317 T8290 punct .,is
R5920 T8465 T8464 punct (,sites
R5921 T8466 T8464 appos M1,sites
R5922 T8467 T8466 cc and,M1
R5923 T8468 T8466 conj M3,M1
R5924 T8318 T8320 det The,probe
R5925 T8469 T8464 punct ),sites
R5926 T8470 T8470 ROOT abolish,abolish
R5927 T8319 T8320 compound 36-bp,probe
R5928 T8471 T8472 poss their,ability
R5929 T8472 T8470 dobj ability,abolish
R5930 T8473 T8474 aux to,compete
R5931 T8320 T8322 nsubjpass probe,shifted
R5932 T8474 T8472 acl compete,ability
R5933 T8475 T8474 prep in,compete
R5934 T8476 T8475 pobj EMSA,in
R5935 T8321 T8322 auxpass was,shifted
R5936 T8477 T8479 punct (,3E
R5937 T8478 T8479 compound Figure,3E
R5938 T8479 T8476 appos 3E,EMSA
R5939 T8322 T8322 ROOT shifted,shifted
R5940 T8480 T8479 punct ),3E
R5941 T8481 T8470 punct .,abolish
R5942 T8482 T8485 det The,probe
R5943 T8323 T8322 agent by,shifted
R5944 T8483 T8485 compound M2,probe
R5945 T8484 T8485 amod mutant,probe
R5946 T8485 T8487 nsubj probe,compete
R5947 T8324 T8327 det the,protein
R5948 T8486 T8487 aux may,compete
R5949 T8487 T8487 ROOT compete,compete
R5950 T8488 T8487 advmod partially,compete
R5951 T8325 T8327 amod tagged,protein
R5952 T8489 T8487 prep with,compete
R5953 T8490 T8489 pobj WT,with
R5954 T8491 T8487 advcl binding,compete
R5955 T8326 T8327 compound Sox6,protein
R5956 T8492 T8487 punct .,compete
R5957 T8493 T8494 aux To,investigate
R5958 T8494 T8516 advcl investigate,co-transfected
R5959 T8495 T8497 det the,significance
R5960 T8496 T8497 amod functional,significance
R5961 T8497 T8494 dobj significance,investigate
R5962 T8521 T8517 pobj vector,with
R5963 T8498 T8497 prep of,significance
R5964 T8499 T8503 det the,sites
R5965 T8500 T8503 amod intact,sites
R5966 T8522 T8521 prep into,vector
R5967 T8501 T8503 nmod Sox/Sox6,sites
R5968 T8502 T8503 amod binding,sites
R5969 T8503 T8498 pobj sites,of
R5970 T8523 T8524 compound GM979,cells
R5971 T8504 T8503 punct ",",sites
R5972 T8505 T8508 det the,reporter
R5973 T8506 T8508 amod ɛy,reporter
R5974 T8524 T8522 pobj cells,into
R5975 T8507 T8508 compound promoter,reporter
R5976 T8508 T8509 nsubj reporter,constructs
R5977 T8509 T8494 dobj constructs,investigate
R5978 T8525 T8516 punct .,co-transfected
R5979 T8510 T8509 prep with,constructs
R5980 T8511 T8512 compound mutagenized,Sox/Sox6
R5981 T8512 T8514 nmod Sox/Sox6,sites
R5982 T8526 T8537 advmod Consistent,constructs
R5983 T8513 T8514 amod binding,sites
R5984 T8514 T8510 pobj sites,with
R5985 T8527 T8526 prep with,Consistent
R5986 T8515 T8516 auxpass were,co-transfected
R5987 T8528 T8530 det the,results
R5988 T8516 T8516 ROOT co-transfected,co-transfected
R5989 T8517 T8516 prep with,co-transfected
R5990 T8529 T8530 compound EMSA,results
R5991 T8518 T8521 det the,vector
R5992 T8519 T8521 amod Sox6,vector
R5993 T8520 T8521 compound overexpression,vector
R5994 T8530 T8527 pobj results,with
R5995 T8531 T8537 punct ",",constructs
R5996 T8532 T8536 det the,reporter
R5997 T8533 T8536 amod mutant,reporter
R5998 T8534 T8536 compound ɛy,reporter
R5999 T8618 T8619 compound liver,cells
R6000 T8535 T8536 compound promoter,reporter
R6001 T8619 T8617 pobj cells,from
R6002 T8620 T8619 prep of,cells
R6003 T8536 T8537 nsubj reporter,constructs
R6004 T8621 T8624 nummod 15.5,mice
R6005 T8622 T8623 compound dpc,WT
R6006 T8537 T8551 nsubj constructs,result
R6007 T8623 T8624 compound WT,mice
R6008 T8624 T8620 pobj mice,of
R6009 T8625 T8612 advcl using,immunoprecipitated
R6010 T8626 T8627 amod Sox6,antibody
R6011 T8627 T8625 dobj antibody,using
R6012 T8628 T8612 punct .,immunoprecipitated
R6013 T8629 T8631 nsubj Figure,shows
R6014 T8538 T8539 punct (,with
R6015 T8630 T8629 nummod 4,Figure
R6016 T8631 T8631 ROOT shows,shows
R6017 T8539 T8537 prep with,constructs
R6018 T8632 T8639 mark that,immunoprecipitated
R6019 T8633 T8636 det the,promoter
R6020 T8540 T8541 det either,one
R6021 T8634 T8636 amod ɛy,promoter
R6022 T8635 T8636 amod proximal,promoter
R6023 T8541 T8539 pobj one,with
R6024 T8636 T8639 nsubjpass promoter,immunoprecipitated
R6025 T8637 T8639 auxpass is,immunoprecipitated
R6026 T8638 T8639 advmod readily,immunoprecipitated
R6027 T8542 T8541 cc or,one
R6028 T8639 T8631 ccomp immunoprecipitated,shows
R6029 T8640 T8639 prep with,immunoprecipitated
R6030 T8641 T8642 amod Sox6,antibody
R6031 T8543 T8546 det both,sites
R6032 T8642 T8640 pobj antibody,with
R6033 T8643 T8639 prep in,immunoprecipitated
R6034 T8644 T8646 det both,cells
R6035 T8544 T8546 amod Sox/Sox6,sites
R6036 T8645 T8646 compound MEL,cells
R6037 T8646 T8643 pobj cells,in
R6038 T8545 T8546 amod binding,sites
R6039 T8647 T8646 cc and,cells
R6040 T8648 T8649 compound liver,cells
R6041 T8649 T8646 conj cells,cells
R6042 T8650 T8631 punct .,shows
R6043 T8546 T8541 conj sites,one
R6044 T8651 T8652 compound Normal,IgG
R6045 T8652 T8654 nsubjpass IgG,used
R6046 T8547 T8541 amod mutagenized,one
R6047 T8653 T8654 auxpass was,used
R6048 T8654 T8654 ROOT used,used
R6049 T8655 T8654 prep as,used
R6050 T8548 T8539 punct ),with
R6051 T8656 T8658 det a,control
R6052 T8657 T8658 amod negative,control
R6053 T8658 T8655 pobj control,as
R6054 T8549 T8551 aux do,result
R6055 T8659 T8661 punct (,4A
R6056 T8660 T8661 compound Figure,4A
R6057 T8661 T8658 appos 4A,control
R6058 T8662 T8661 punct ),4A
R6059 T8663 T8654 punct .,used
R6060 T8664 T8666 det The,data
R6061 T8665 T8666 amod above,data
R6062 T8550 T8551 neg not,result
R6063 T8666 T8674 nsubj data,indicate
R6064 T8667 T8668 punct (,Figures
R6065 T8551 T8551 ROOT result,result
R6066 T8668 T8674 nsubj Figures,indicate
R6067 T8669 T8668 nummod 3,Figures
R6068 T8670 T8669 cc and,3
R6069 T8671 T8668 appos 4,Figures
R6070 T8552 T8551 prep in,result
R6071 T8553 T8555 amod significant,repression
R6072 T8672 T8668 punct ),Figures
R6073 T8673 T8674 advmod clearly,indicate
R6074 T8554 T8555 compound promoter,repression
R6075 T8674 T8674 ROOT indicate,indicate
R6076 T8675 T8687 mark that,binding
R6077 T8676 T8677 amod Sox6,acts
R6078 T8555 T8552 pobj repression,in
R6079 T8677 T8687 nsubj acts,binding
R6080 T8678 T8677 prep as,acts
R6081 T8556 T8555 prep in,repression
R6082 T8679 T8680 det a,repressor
R6083 T8680 T8678 pobj repressor,as
R6084 T8681 T8680 prep of,repressor
R6085 T8557 T8558 compound transfection,studies
R6086 T8682 T8684 det the,gene
R6087 T8683 T8684 compound ɛy,gene
R6088 T8684 T8681 pobj gene,of
R6089 T8558 T8556 pobj studies,in
R6090 T8685 T8677 prep by,acts
R6091 T8686 T8687 advmod directly,binding
R6092 T8687 T8674 ccomp binding,indicate
R6093 T8559 T8560 punct (,Figure
R6094 T8688 T8687 prep to,binding
R6095 T8689 T8691 det the,promoter
R6096 T8560 T8558 appos Figure,studies
R6097 T8690 T8691 amod ɛy,promoter
R6098 T8691 T8688 pobj promoter,to
R6099 T8692 T8674 punct ",",indicate
R6100 T8561 T8560 nummod 3F,Figure
R6101 T8693 T8694 advmod probably,as
R6102 T8694 T8674 prep as,indicate
R6103 T8695 T8696 det a,dimer
R6104 T8562 T8560 punct ),Figure
R6105 T8696 T8694 pobj dimer,as
R6106 T8697 T8674 punct .,indicate
R6107 T8563 T8551 punct .,result
R6108 T8564 T8569 advmod Thus,required
R6109 T8565 T8569 punct ",",required
R6110 T8566 T8567 det both,sites
R6111 T8567 T8569 nsubjpass sites,required
R6112 T8568 T8569 auxpass are,required
R6113 T8569 T8569 ROOT required,required
R6114 T8570 T8569 prep for,required
R6115 T8571 T8572 amod maximal,repression
R6116 T8572 T8570 pobj repression,for
R6119 T8573 T8572 prep of,repression
R6120 T8574 T8573 pobj ɛy,of
R6122 T8575 T8569 agent by,required
R6123 T8576 T8575 pobj Sox6,by
R6124 T8577 T8569 punct ",",required
R6126 T8578 T8569 cc but,required
R6127 T8579 T8580 neg not,to
R6129 T8580 T8569 xcomp to,required
R6131 T8581 T8583 det the,degree
R6133 T8582 T8583 amod same,degree
R6136 T8583 T8580 pobj degree,to
R6139 T8584 T8569 punct .,required
R6141 T8585 T8587 nsubj We,tested
R6142 T8586 T8587 advmod also,tested
R6143 T8587 T8587 ROOT tested,tested
R6145 T8588 T8590 nmod whether,binds
R6146 T8589 T8590 amod Sox6,binds
R6149 T8590 T8587 dobj binds,tested
R6151 T8591 T8590 prep to,binds
R6152 T8592 T8594 det the,promoter
R6153 T8593 T8594 amod ɛy,promoter
R6154 T8594 T8591 pobj promoter,to
R6157 T8595 T8594 prep in,promoter
R6159 T8596 T8595 pobj vivo,in
R6160 T8597 T8590 acl using,binds
R6161 T8598 T8599 compound chromatin,immunoprecipitation
R6162 T8599 T8597 dobj immunoprecipitation,using
R6163 T8600 T8599 punct (,immunoprecipitation
R6164 T8601 T8599 appos ChIP,immunoprecipitation
R6165 T8602 T8599 punct ),immunoprecipitation
R6166 T8603 T8604 punct (,Figure
R6167 T8604 T8590 appos Figure,binds
R6169 T8605 T8604 nummod 4,Figure
R6171 T8606 T8604 punct ),Figure
R6172 T8607 T8587 punct .,tested
R6174 T8608 T8610 det The,complex
R6175 T8609 T8610 amod Sox6-containing,complex
R6176 T8610 T8612 nsubjpass complex,immunoprecipitated
R6179 T8611 T8612 auxpass was,immunoprecipitated
R6180 T8612 T8612 ROOT immunoprecipitated,immunoprecipitated
R6182 T8613 T8612 prep from,immunoprecipitated
R6183 T8614 T8615 compound MEL,cells
R6184 T8615 T8613 pobj cells,from
R6185 T8616 T8613 cc or,from
R6189 T8617 T8613 conj from,from
R6518 T9421 T9423 det The,Expression
R6519 T9422 T9423 compound Persistent,Expression
R6520 T9423 T9423 ROOT Expression,Expression
R6521 T9424 T9423 prep of,Expression
R6522 T9425 T9426 compound ɛy,Globin
R6523 T9426 T9424 pobj Globin,of
R6524 T9427 T9423 prep in,Expression
R6525 T9428 T9427 pobj Sox6-Deficient,in
R6526 T9429 T9430 nsubj Mice,Is
R6527 T9430 T9430 ROOT Is,Is
R6528 T9431 T9430 acomp Due,Is
R6529 T9432 T9431 prep to,Due
R6530 T9433 T9434 det a,Defect
R6531 T9434 T9432 pobj Defect,to
R6532 T9435 T9434 prep in,Defect
R6533 T9436 T9437 det the,ɛy-Gene
R6534 T9437 T9435 pobj ɛy-Gene,in
R6535 T9438 T9431 xcomp Silencing,Due
R6536 T9439 T9438 dobj Mechanism,Silencing
R6537 T9440 T9438 prep in,Silencing
R6538 T9441 T9444 compound Definitive,Normally
R6539 T9442 T9444 compound Erythroid,Normally
R6540 T9443 T9444 compound Cells,Normally
R6541 T9444 T9440 pobj Normally,in
R6542 T9445 T9452 punct ",",expressed
R6543 T9446 T9449 det the,gene
R6544 T9447 T9449 amod ɛy,gene
R6545 T9448 T9449 compound globin,gene
R6546 T9449 T9452 nsubjpass gene,expressed
R6547 T9450 T9452 auxpass is,expressed
R6548 T9451 T9452 advmod exclusively,expressed
R6549 T9452 T9430 ccomp expressed,Is
R6550 T9453 T9452 prep in,expressed
R6551 T9454 T9455 amod primitive,erythrocytes
R6552 T9455 T9453 pobj erythrocytes,in
R6553 T9456 T9452 cc and,expressed
R6554 T9457 T9452 conj silenced,expressed
R6555 T9458 T9457 prep in,silenced
R6556 T9459 T9460 amod definitive,erythrocytes
R6557 T9460 T9458 pobj erythrocytes,in
R6558 T9461 T9452 punct .,expressed
R6559 T9462 T9463 aux To,determine
R6560 T9463 T9463 ROOT determine,determine
R6561 T9464 T9471 mark whether,is
R6562 T9465 T9467 det the,expression
R6563 T9466 T9467 amod persistent,expression
R6564 T9467 T9471 nsubj expression,is
R6565 T9468 T9467 prep of,expression
R6566 T9469 T9470 amod ɛy,globin
R6567 T9470 T9468 pobj globin,of
R6568 T9471 T9463 ccomp is,determine
R6569 T9472 T9471 acomp due,is
R6570 T9473 T9472 prep to,due
R6571 T9474 T9476 amod residual,erythrocytes
R6572 T9475 T9476 amod primitive,erythrocytes
R6573 T9476 T9473 pobj erythrocytes,to
R6574 T9477 T9471 cc or,is
R6575 T9478 T9471 conj is,is
R6576 T9479 T9478 acomp due,is
R6577 T9480 T9479 prep to,due
R6578 T9481 T9482 amod ectopic,expression
R6579 T9482 T9480 pobj expression,to
R6580 T9483 T9482 prep of,expression
R6581 T9484 T9485 amod ɛy,globin
R6582 T9485 T9483 pobj globin,of
R6583 T9486 T9479 prep in,due
R6584 T9487 T9488 amod definitive,erythrocytes
R6585 T9488 T9486 pobj erythrocytes,in
R6586 T9489 T9491 punct ",",examined
R6587 T9490 T9491 nsubj we,examined
R6588 T9491 T9478 ccomp examined,is
R6589 T9492 T9494 det the,pattern
R6590 T9493 T9494 amod spatial,pattern
R6591 T9494 T9491 dobj pattern,examined
R6592 T9495 T9494 prep of,pattern
R6593 T9496 T9498 amod ɛy,transcripts
R6594 T9497 T9498 compound globin,transcripts
R6595 T9498 T9495 pobj transcripts,of
R6596 T9499 T9491 prep in,examined
R6597 T9500 T9501 compound mouse,embryos
R6598 T9501 T9499 pobj embryos,in
R6599 T9502 T9491 prep by,examined
R6600 T9503 T9491 prep in,examined
R6601 T9504 T9505 compound situ,hybridization
R6602 T9505 T9503 pobj hybridization,in
R6603 T9506 T9507 punct (,Figure
R6604 T9507 T9491 parataxis Figure,examined
R6605 T9508 T9507 nummod 5,Figure
R6606 T9509 T9507 punct ),Figure
R6607 T9510 T9463 punct .,determine
R6608 T9511 T9512 mark As,expected
R6609 T9512 T9518 advcl expected,expressed
R6610 T9513 T9518 punct ",",expressed
R6611 T9514 T9515 amod ɛy,globin
R6612 T9515 T9518 nsubjpass globin,expressed
R6613 T9516 T9518 auxpass is,expressed
R6614 T9517 T9518 neg not,expressed
R6615 T9518 T9518 ROOT expressed,expressed
R6616 T9519 T9518 prep in,expressed
R6617 T9520 T9523 det the,liver
R6618 T9521 T9523 nmod WT,liver
R6619 T9522 T9523 amod 14.5-dpc,liver
R6620 T9523 T9519 pobj liver,in
R6621 T9524 T9523 punct ",",liver
R6622 T9525 T9526 det the,site
R6623 T9526 T9523 appos site,liver
R6624 T9527 T9526 prep of,site
R6625 T9528 T9529 amod definitive,erythropoiesis
R6626 T9529 T9527 pobj erythropoiesis,of
R6627 T9530 T9526 prep in,site
R6628 T9531 T9532 det the,fetus
R6629 T9532 T9530 pobj fetus,in
R6630 T9533 T9518 punct .,expressed
R6631 T9534 T9543 prep In,seen
R6632 T9535 T9534 pobj contrast,In
R6633 T9536 T9543 punct ",",seen
R6634 T9537 T9541 amod abundant,expression
R6635 T9538 T9539 amod ectopic,ɛy
R6636 T9539 T9541 compound ɛy,expression
R6637 T9540 T9541 compound mRNA,expression
R6638 T9541 T9543 nsubjpass expression,seen
R6639 T9542 T9543 auxpass is,seen
R6640 T9543 T9543 ROOT seen,seen
R6641 T9544 T9543 prep in,seen
R6642 T9545 T9546 det the,liver
R6643 T9546 T9544 pobj liver,in
R6644 T9547 T9546 prep of,liver
R6645 T9548 T9549 amod 14.5-dpc,mutants
R6646 T9549 T9547 pobj mutants,of
R6647 T9550 T9551 punct (,Figure
R6648 T9551 T9543 dobj Figure,seen
R6649 T9552 T9551 nummod 5,Figure
R6650 T9553 T9551 appos A,Figure
R6651 T9554 T9553 appos D,A
R6652 T9555 T9551 punct ),Figure
R6653 T9556 T9543 punct .,seen
R6654 T9557 T9566 advmod However,is
R6655 T9558 T9566 punct ",",is
R6656 T9559 T9560 det the,expression
R6657 T9560 T9566 nsubj expression,is
R6658 T9561 T9560 prep of,expression
R6659 T9562 T9565 compound βmaj,globin
R6660 T9563 T9565 compound /,globin
R6661 T9564 T9565 compound min,globin
R6662 T9565 T9561 pobj globin,of
R6663 T9566 T9566 ROOT is,is
R6664 T9567 T9568 advmod equally,abundant
R6665 T9568 T9566 acomp abundant,is
R6666 T9569 T9568 prep in,abundant
R6667 T9570 T9571 preconj both,WT
R6668 T9571 T9575 nmod WT,mice
R6669 T9572 T9571 cc and,WT
R6670 T9573 T9571 conj p100H,WT
R6671 T9574 T9575 amod mutant,mice
R6672 T9575 T9569 pobj mice,in
R6673 T9576 T9577 punct (,Figure
R6674 T9577 T9575 appos Figure,mice
R6675 T9578 T9577 nummod 5,Figure
R6676 T9579 T9577 appos E,Figure
R6677 T9580 T9579 cc and,E
R6678 T9581 T9579 conj F,E
R6679 T9582 T9581 punct ),F
R6680 T9583 T9566 punct .,is
R6681 T9584 T9585 det These,data
R6682 T9585 T9586 nsubj data,demonstrate
R6683 T9586 T9586 ROOT demonstrate,demonstrate
R6684 T9587 T9594 mark that,are
R6685 T9588 T9591 det the,levels
R6686 T9589 T9591 amod persistent,levels
R6687 T9590 T9591 amod high,levels
R6688 T9591 T9594 nsubj levels,are
R6689 T9592 T9591 prep of,levels
R6690 T9593 T9592 pobj ɛy,of
R6691 T9594 T9586 ccomp are,demonstrate
R6692 T9595 T9594 acomp due,are
R6693 T9596 T9597 aux to,ectopic
R6694 T9597 T9595 xcomp ectopic,due
R6695 T9598 T9597 dobj expression,ectopic
R6696 T9599 T9597 prep in,ectopic
R6697 T9600 T9603 det the,cells
R6698 T9601 T9603 amod definitive,cells
R6699 T9602 T9603 amod erythroid,cells
R6700 T9603 T9599 pobj cells,in
R6701 T9604 T9605 nsubj that,mature
R6702 T9605 T9603 relcl mature,cells
R6703 T9606 T9605 prep in,mature
R6704 T9607 T9609 det the,liver
R6705 T9608 T9609 amod fetal,liver
R6706 T9609 T9606 pobj liver,in
R6707 T9610 T9586 punct ",",demonstrate
R6708 T9611 T9586 advcl suggesting,demonstrate
R6709 T9612 T9614 mark that,is
R6710 T9613 T9614 expl there,is
R6711 T9614 T9611 ccomp is,suggesting
R6712 T9615 T9617 det an,defect
R6713 T9616 T9617 amod intrinsic,defect
R6714 T9617 T9614 attr defect,is
R6715 T9618 T9617 prep of,defect
R6716 T9619 T9620 det the,ɛy
R6717 T9620 T9618 pobj ɛy,of
R6718 T9621 T9617 acl silencing,defect
R6719 T9622 T9621 dobj mechanism,silencing
R6720 T9623 T9621 prep in,silencing
R6721 T9624 T9625 amod Sox6-null,mice
R6722 T9625 T9623 pobj mice,in
R6723 T9626 T9586 punct .,demonstrate
R6969 T10094 T10096 det The,Pattern
R6970 T10095 T10096 compound Expression,Pattern
R6971 T10096 T10099 nsubj Pattern,Suggests
R6972 T10097 T10096 prep of,Pattern
R6973 T10098 T10097 pobj Sox6,of
R6974 T10099 T10099 ROOT Suggests,Suggests
R6975 T10100 T10101 det a,Role
R6976 T10101 T10099 dobj Role,Suggests
R6977 T10102 T10101 prep in,Role
R6978 T10103 T10104 amod Definitive,Erythropoiesis
R6979 T10104 T10102 pobj Erythropoiesis,in
R6980 T10105 T10106 det The,observation
R6981 T10106 T10123 nsubj observation,suggests
R6982 T10107 T10111 mark that,express
R6983 T10108 T10109 amod Sox6-deficient,mice
R6984 T10109 T10111 nsubj mice,express
R6985 T10110 T10111 advmod ectopically,express
R6986 T10111 T10106 acl express,observation
R6987 T10112 T10113 amod ɛy,globin
R6988 T10113 T10111 dobj globin,express
R6989 T10114 T10113 prep in,globin
R6990 T10115 T10114 pobj liver,in
R6991 T10116 T10115 punct ",",liver
R6992 T10117 T10121 advmod where,mature
R6993 T10118 T10120 amod definitive,cells
R6994 T10119 T10120 amod erythroid,cells
R6995 T10120 T10121 nsubj cells,mature
R6996 T10121 T10115 relcl mature,liver
R6997 T10122 T10123 punct ",",suggests
R6998 T10123 T10123 ROOT suggests,suggests
R6999 T10124 T10126 mark that,is
R7000 T10125 T10126 nsubj Sox6,is
R7001 T10126 T10123 ccomp is,suggests
R7002 T10127 T10129 det an,regulator
R7003 T10128 T10129 amod important,regulator
R7004 T10129 T10126 attr regulator,is
R7005 T10130 T10129 prep in,regulator
R7006 T10131 T10132 amod definitive,erythropoiesis
R7007 T10132 T10130 pobj erythropoiesis,in
R7008 T10133 T10123 punct .,suggests
R7009 T10134 T10135 aux To,determine
R7010 T10135 T10153 advcl determine,employed
R7011 T10136 T10141 det the,pattern
R7012 T10137 T10141 amod temporal,pattern
R7013 T10138 T10137 cc and,temporal
R7014 T10139 T10137 conj spatial,temporal
R7015 T10140 T10141 compound expression,pattern
R7016 T10141 T10135 dobj pattern,determine
R7017 T10142 T10141 prep of,pattern
R7018 T10143 T10142 pobj Sox6,of
R7019 T10144 T10143 punct ",",Sox6
R7020 T10145 T10146 compound Northern,blot
R7021 T10146 T10141 conj blot,pattern
R7022 T10147 T10146 cc and,blot
R7023 T10148 T10146 conj in,blot
R7024 T10149 T10151 compound situ,assays
R7025 T10150 T10151 compound hybridization,assays
R7026 T10151 T10148 pobj assays,in
R7027 T10152 T10153 auxpass were,employed
R7028 T10153 T10153 ROOT employed,employed
R7029 T10154 T10153 punct .,employed
R7030 T10155 T10156 mark As,shown
R7031 T10156 T10162 advcl shown,is
R7032 T10157 T10156 prep in,shown
R7033 T10158 T10157 pobj Figure,in
R7034 T10159 T10158 nummod 6A,Figure
R7035 T10160 T10162 punct ",",is
R7036 T10161 T10162 nsubj Sox6,is
R7037 T10162 T10162 ROOT is,is
R7038 T10163 T10162 acomp detectable,is
R7039 T10164 T10163 prep by,detectable
R7040 T10165 T10166 compound Northern,blot
R7041 T10166 T10164 pobj blot,by
R7042 T10167 T10162 advcl beginning,is
R7043 T10168 T10167 prep at,beginning
R7044 T10169 T10170 nummod 10.5,dpc
R7045 T10170 T10168 pobj dpc,at
R7046 T10171 T10170 punct ",",dpc
R7047 T10172 T10170 amod coincident,dpc
R7048 T10173 T10172 prep with,coincident
R7049 T10174 T10176 det the,onset
R7050 T10175 T10176 amod temporal,onset
R7051 T10176 T10173 pobj onset,with
R7052 T10177 T10176 prep of,onset
R7053 T10178 T10179 amod definitive,erythropoiesis
R7054 T10179 T10177 pobj erythropoiesis,of
R7055 T10180 T10179 prep in,erythropoiesis
R7056 T10181 T10182 det the,liver
R7057 T10182 T10180 pobj liver,in
R7058 T10183 T10162 punct .,is
R7059 T10184 T10189 advmod Furthermore,shows
R7060 T10185 T10189 punct ",",shows
R7061 T10186 T10189 prep in,shows
R7062 T10187 T10188 compound situ,hybridization
R7063 T10188 T10189 compound hybridization,shows
R7064 T10189 T10189 ROOT shows,shows
R7065 T10190 T10194 mark that,transcribed
R7066 T10191 T10194 nsubjpass Sox6,transcribed
R7067 T10192 T10194 auxpass is,transcribed
R7068 T10193 T10194 advmod highly,transcribed
R7069 T10194 T10189 ccomp transcribed,shows
R7070 T10195 T10194 prep in,transcribed
R7071 T10196 T10197 amod 12.5-dpc,liver
R7072 T10197 T10195 pobj liver,in
R7073 T10198 T10194 punct ",",transcribed
R7074 T10199 T10194 cc but,transcribed
R7075 T10200 T10201 neg not,in
R7076 T10201 T10206 prep in,at
R7077 T10202 T10203 compound yolk,sac
R7078 T10203 T10205 compound sac,islands
R7079 T10204 T10205 compound blood,islands
R7080 T10205 T10201 pobj islands,in
R7081 T10206 T10194 conj at,transcribed
R7082 T10207 T10208 nummod 7.5,dpc
R7083 T10208 T10206 pobj dpc,at
R7084 T10209 T10211 punct (,6B
R7085 T10210 T10211 compound Figure,6B
R7086 T10211 T10208 appos 6B,dpc
R7087 T10212 T10211 punct ),6B
R7088 T10213 T10189 punct .,shows
R7089 T10214 T10218 advmod Therefore,is
R7090 T10215 T10218 punct ",",is
R7091 T10216 T10217 amod Sox6,expression
R7092 T10217 T10218 nsubj expression,is
R7093 T10218 T10218 ROOT is,is
R7094 T10219 T10222 advmod temporally,coincident
R7095 T10220 T10219 cc and,temporally
R7096 T10221 T10219 conj spatially,temporally
R7097 T10222 T10218 acomp coincident,is
R7098 T10223 T10222 prep with,coincident
R7099 T10224 T10223 pobj definitive,with
R7100 T10225 T10222 punct ",",coincident
R7101 T10226 T10222 cc but,coincident
R7102 T10227 T10228 neg not,primitive
R7103 T10228 T10222 conj primitive,coincident
R7104 T10229 T10228 punct ",",primitive
R7105 T10230 T10228 conj erythropoiesis,primitive
R7106 T10231 T10218 punct .,is
R7107 T10232 T10233 det These,data
R7108 T10233 T10260 nsubj data,demonstrate
R7109 T10234 T10233 punct ",",data
R7110 T10235 T10233 acl taken,data
R7111 T10236 T10235 advmod together,taken
R7112 T10237 T10235 prep with,taken
R7113 T10238 T10239 det the,observation
R7114 T10239 T10237 pobj observation,with
R7115 T10240 T10245 mark that,expressed
R7116 T10241 T10242 amod ɛy,globin
R7117 T10242 T10245 nsubjpass globin,expressed
R7118 T10243 T10245 auxpass is,expressed
R7119 T10244 T10245 advmod highly,expressed
R7120 T10245 T10239 acl expressed,observation
R7121 T10246 T10245 prep in,expressed
R7122 T10247 T10249 det the,cells
R7123 T10248 T10249 compound liver,cells
R7124 T10249 T10246 pobj cells,in
R7125 T10250 T10249 prep of,cells
R7126 T10251 T10254 amod 14.5-dpc,mice
R7127 T10252 T10254 amod p100H,mice
R7128 T10253 T10254 amod mutant,mice
R7129 T10254 T10250 pobj mice,of
R7130 T10255 T10256 punct (,Figure
R7131 T10256 T10249 appos Figure,cells
R7132 T10257 T10256 nummod 5,Figure
R7133 T10258 T10256 punct ),Figure
R7134 T10259 T10260 punct ",",demonstrate
R7135 T10260 T10260 ROOT demonstrate,demonstrate
R7136 T10261 T10263 mark that,functions
R7137 T10262 T10263 amod Sox6,functions
R7138 T10263 T10260 ccomp functions,demonstrate
R7139 T10264 T10263 prep in,functions
R7140 T10265 T10266 amod definitive,erythropoiesis
R7141 T10266 T10264 pobj erythropoiesis,in
R7142 T10267 T10260 punct .,demonstrate
R7298 T10522 T10523 compound Mutant,p100H
R7299 T10523 T10523 ROOT p100H,p100H
R7300 T10524 T10542 nsubj Mice,noticed
R7301 T10525 T10532 preconj Have,Among
R7302 T10526 T10527 amod Higher,Numbers
R7303 T10527 T10525 dobj Numbers,Have
R7304 T10528 T10527 prep of,Numbers
R7305 T10529 T10531 compound Nucleated,Cells
R7306 T10530 T10531 compound Red,Cells
R7307 T10531 T10528 pobj Cells,of
R7308 T10532 T10542 prep Among,noticed
R7309 T10533 T10536 det the,effects
R7310 T10534 T10536 amod other,effects
R7311 T10535 T10536 amod Sox6,effects
R7312 T10536 T10532 pobj effects,Among
R7313 T10537 T10536 prep in,effects
R7314 T10538 T10537 pobj erythropoiesis,in
R7315 T10539 T10542 punct ",",noticed
R7316 T10540 T10542 nsubj we,noticed
R7317 T10541 T10542 aux have,noticed
R7318 T10542 T10542 ROOT noticed,noticed
R7319 T10543 T10545 mark that,are
R7320 T10544 T10545 expl there,are
R7321 T10545 T10542 ccomp are,noticed
R7322 T10546 T10547 advmod more,nucleated
R7323 T10547 T10550 amod nucleated,cells
R7324 T10548 T10550 amod red,cells
R7325 T10549 T10550 compound blood,cells
R7326 T10550 T10545 attr cells,are
R7327 T10551 T10550 acl circulating,cells
R7328 T10552 T10551 prep in,circulating
R7329 T10553 T10555 amod p100H,mice
R7330 T10554 T10555 amod mutant,mice
R7331 T10555 T10552 pobj mice,in
R7332 T10556 T10550 prep than,cells
R7333 T10557 T10556 prep in,than
R7334 T10558 T10559 compound WT,mice
R7335 T10559 T10557 pobj mice,in
R7336 T10560 T10545 prep at,are
R7337 T10561 T10560 pobj 14.5,at
R7338 T10562 T10569 nmod dpc,)
R7339 T10563 T10562 cc and,dpc
R7340 T10564 T10565 nummod 18.5,dpc
R7341 T10565 T10569 nmod dpc,)
R7342 T10566 T10568 punct (,7A
R7343 T10567 T10568 compound Figure,7A
R7344 T10568 T10565 appos 7A,dpc
R7345 T10569 T10545 punct ),are
R7346 T10570 T10542 punct .,noticed
R7347 T10571 T10581 advmod However,see
R7348 T10572 T10581 punct ",",see
R7349 T10573 T10581 prep at,see
R7350 T10574 T10575 amod postnatal,day
R7351 T10575 T10573 pobj day,at
R7352 T10576 T10575 nummod 10.5,day
R7353 T10577 T10581 punct ",",see
R7354 T10578 T10581 nsubj we,see
R7355 T10579 T10581 aux do,see
R7356 T10580 T10581 neg not,see
R7357 T10581 T10581 ROOT see,see
R7358 T10582 T10581 ccomp circulating,see
R7359 T10583 T10585 amod nucleated,cells
R7360 T10584 T10585 amod red,cells
R7361 T10585 T10582 dobj cells,circulating
R7362 T10586 T10582 prep in,circulating
R7363 T10587 T10588 det either,WT
R7364 T10588 T10586 pobj WT,in
R7365 T10589 T10588 cc or,WT
R7366 T10590 T10591 amod mutant,mice
R7367 T10591 T10588 conj mice,WT
R7368 T10592 T10582 punct ",",circulating
R7369 T10593 T10582 advcl suggesting,circulating
R7370 T10594 T10597 mark that,be
R7371 T10595 T10597 nsubj this,be
R7372 T10596 T10597 aux may,be
R7373 T10597 T10593 ccomp be,suggesting
R7374 T10598 T10600 det a,effect
R7375 T10599 T10600 amod transient,effect
R7376 T10600 T10597 attr effect,be
R7377 T10601 T10581 punct .,see
R7378 T10602 T10608 prep In,shows
R7379 T10603 T10602 pobj addition,In
R7380 T10604 T10608 punct ",",shows
R7381 T10605 T10607 det the,liver
R7382 T10606 T10607 amod mutant,liver
R7383 T10607 T10608 nsubj liver,shows
R7384 T10608 T10608 ROOT shows,shows
R7385 T10609 T10611 det a,increase
R7386 T10610 T10611 amod significant,increase
R7387 T10611 T10608 dobj increase,shows
R7388 T10612 T10611 prep in,increase
R7389 T10613 T10615 amod hematopoietic,cells
R7390 T10614 T10615 compound precursor,cells
R7391 T10615 T10612 pobj cells,in
R7392 T10616 T10615 prep including,cells
R7393 T10617 T10618 amod nucleated,erythrocytes
R7394 T10618 T10616 pobj erythrocytes,including
R7395 T10619 T10618 prep at,erythrocytes
R7396 T10620 T10621 nummod 18.5,dpc
R7397 T10621 T10619 pobj dpc,at
R7398 T10622 T10624 punct (,7B
R7399 T10623 T10624 compound Figure,7B
R7400 T10624 T10621 appos 7B,dpc
R7401 T10625 T10624 punct ),7B
R7402 T10626 T10608 punct .,shows
R7403 T10627 T10628 det This,alteration
R7404 T10628 T10630 nsubjpass alteration,noted
R7405 T10629 T10630 auxpass is,noted
R7406 T10630 T10630 ROOT noted,noted
R7407 T10631 T10632 advmod as,early
R7408 T10632 T10630 advmod early,noted
R7409 T10633 T10632 prep as,early
R7410 T10634 T10635 nummod 14.5,dpc
R7411 T10635 T10633 pobj dpc,as
R7412 T10636 T10630 punct .,noted
R7413 T10637 T10638 det These,observations
R7414 T10638 T10639 nsubj observations,suggest
R7415 T10639 T10639 ROOT suggest,suggest
R7416 T10640 T10650 mark that,affect
R7417 T10641 T10650 prep besides,affect
R7418 T10642 T10641 pcomp silencing,besides
R7419 T10643 T10646 det the,gene
R7420 T10644 T10646 amod ɛy,gene
R7421 T10645 T10646 compound globin,gene
R7422 T10646 T10642 dobj gene,silencing
R7423 T10647 T10650 punct ",",affect
R7424 T10648 T10650 nsubj Sox6,affect
R7425 T10649 T10650 aux may,affect
R7426 T10650 T10639 ccomp affect,suggest
R7427 T10651 T10652 amod red,cell
R7428 T10652 T10653 compound cell,maturation
R7429 T10653 T10650 dobj maturation,affect
R7430 T10654 T10639 punct .,suggest
R9403 T13803 T13808 prep In,show
R9404 T13804 T13805 det this,report
R9405 T13805 T13803 pobj report,In
R9406 T13806 T13808 punct ",",show
R9407 T13807 T13808 nsubj we,show
R9408 T13808 T13808 ROOT show,show
R9409 T13809 T13811 mark that,is
R9410 T13810 T13811 nsubj Sox6,is
R9411 T13811 T13808 ccomp is,show
R9412 T13812 T13814 det a,factor
R9413 T13813 T13814 amod novel,factor
R9414 T13814 T13811 attr factor,is
R9415 T13815 T13814 prep in,factor
R9416 T13816 T13819 det the,mechanism
R9417 T13817 T13819 amod complicated,mechanism
R9419 T13818 T13819 compound regulation,mechanism
R9420 T13819 T13815 pobj mechanism,in
R9421 T13820 T13819 prep of,mechanism
R9422 T13821 T13822 compound globin,genes
R9423 T13822 T13820 pobj genes,of
R9424 T13823 T13808 punct .,show
R9425 T13824 T13831 prep In,is
R9426 T13825 T13828 det the,mouse
R9428 T13826 T13828 compound Sox6,mouse
R9429 T13827 T13828 amod null,mouse
R9430 T13828 T13824 pobj mouse,In
R9431 T13829 T13831 punct ",",is
R9433 T13830 T13831 expl there,is
R9434 T13831 T13831 ROOT is,is
R9436 T13832 T13834 det a,effect
R9438 T13833 T13834 amod transient,effect
R9439 T13834 T13831 attr effect,is
R9441 T13846 T13848 det a,upregulation
R9442 T13835 T13834 prep on,effect
R9443 T13836 T13839 det the,genes
R9444 T13837 T13839 amod embryonic,genes
R9445 T13838 T13839 compound globin,genes
R9446 T13839 T13835 pobj genes,on
R9447 T13840 T13839 punct ",",genes
R9448 T13841 T13839 conj ζ,genes
R9449 T13842 T13841 cc and,ζ
R9450 T13843 T13841 conj βH1,ζ
R9451 T13844 T13843 punct ",",βH1
R9452 T13845 T13843 cc and,βH1
R9453 T13847 T13848 amod persistent,upregulation
R9454 T13848 T13843 conj upregulation,βH1
R9455 T13849 T13848 prep of,upregulation
R9456 T13850 T13853 det the,gene
R9457 T13877 T13877 ROOT belongs,belongs
R9458 T13851 T13853 amod ɛy,gene
R9459 T13878 T13879 aux to,group
R9460 T13879 T13877 xcomp group,belongs
R9461 T13852 T13853 compound globin,gene
R9462 T13880 T13879 dobj D,group
R9463 T13881 T13880 prep of,D
R9464 T13882 T13884 det the,family
R9465 T13853 T13849 pobj gene,of
R9466 T13883 T13884 compound Sox,family
R9467 T13884 T13881 pobj family,of
R9468 T13854 T13831 punct .,is
R9469 T13885 T13884 prep of,family
R9470 T13886 T13885 pobj proteins,of
R9471 T13887 T13888 nsubj that,includes
R9472 T13855 T13857 nsubj Sox6,regulates
R9473 T13888 T13884 relcl includes,family
R9474 T13889 T13888 dobj Sox5,includes
R9475 T13856 T13857 advmod directly,regulates
R9476 T13890 T13889 punct ",",Sox5
R9477 T13891 T13888 npadvmod 12,includes
R9478 T13892 T13893 punct ",",13
R9479 T13893 T13891 prep 13,12
R9480 T13857 T13857 ROOT regulates,regulates
R9481 T13894 T13891 punct ",",12
R9482 T13895 T13891 cc and,12
R9483 T13858 T13857 cc and,regulates
R9484 T13896 T13899 nummod 23,]
R9485 T13897 T13899 nmod [,]
R9486 T13859 T13857 conj binds,regulates
R9487 T13898 T13899 nummod 34,]
R9488 T13899 T13891 conj ],12
R9489 T13900 T13877 punct .,belongs
R9490 T13860 T13859 prep to,binds
R9491 T13901 T13904 compound Group,proteins
R9492 T13902 T13904 compound D,proteins
R9493 T13903 T13904 compound Sox,proteins
R9494 T13861 T13863 det the,promoter
R9495 T13904 T13905 nsubj proteins,contain
R9496 T13905 T13905 ROOT contain,contain
R9497 T13906 T13907 det a,coiled
R9498 T13862 T13863 amod proximal,promoter
R9499 T13907 T13909 amod coiled,domain
R9500 T13908 T13909 compound coiled,domain
R9501 T13909 T13905 dobj domain,contain
R9502 T13863 T13860 pobj promoter,to
R9503 T13864 T13863 prep of,promoter
R9504 T13910 T13911 nsubj that,mediates
R9505 T13911 T13909 relcl mediates,domain
R9506 T13912 T13916 nmod homo,[
R9507 T13913 T13912 punct -,homo
R9508 T13914 T13912 cc and,homo
R9509 T13915 T13912 conj heterodimerization,homo
R9510 T13865 T13866 amod ɛy,gene
R9511 T13916 T13918 compound [,]
R9512 T13917 T13918 compound "6,35",]
R9513 T13866 T13864 pobj gene,of
R9514 T13918 T13911 dobj ],mediates
R9515 T13919 T13905 punct .,contain
R9516 T13867 T13863 cc and,promoter
R9517 T13920 T13929 advmod Functionally,shown
R9518 T13921 T13929 punct ",",shown
R9519 T13868 T13857 conj represses,regulates
R9520 T13922 T13929 nsubjpass dimerization,shown
R9521 T13923 T13922 prep of,dimerization
R9522 T13924 T13923 pobj Sox5,of
R9523 T13869 T13871 det the,gene
R9524 T13925 T13922 cc and,dimerization
R9525 T13926 T13922 conj Sox6,dimerization
R9526 T13927 T13929 aux has,shown
R9527 T13928 T13929 auxpass been,shown
R9528 T13870 T13871 amod ɛy-globin,gene
R9529 T13929 T13929 ROOT shown,shown
R9530 T13930 T13932 aux to,increase
R9531 T13931 T13932 advmod greatly,increase
R9532 T13871 T13868 dobj gene,represses
R9533 T13932 T13929 xcomp increase,shown
R9534 T13933 T13935 det the,efficiency
R9535 T13934 T13935 amod binding,efficiency
R9536 T13872 T13871 prep in,gene
R9537 T13935 T13932 dobj efficiency,increase
R9538 T13873 T13874 amod definitive,erythropoiesis
R9539 T13936 T13935 prep of,efficiency
R9540 T13937 T13940 det the,proteins
R9541 T13938 T13940 nummod two,proteins
R9542 T13939 T13940 compound Sox,proteins
R9543 T13874 T13872 pobj erythropoiesis,in
R9544 T13940 T13936 pobj proteins,of
R9545 T13941 T13932 prep to,increase
R9546 T13942 T13941 pobj DNA,to
R9547 T13875 T13857 punct .,regulates
R9548 T13943 T13944 nsubj that,contains
R9549 T13944 T13929 conj contains,shown
R9550 T13876 T13877 nsubj Sox6,belongs
R9551 T13945 T13947 amod adjacent,sites
R9552 T13946 T13947 compound Sox,sites
R9553 T13947 T13944 dobj sites,contains
R9554 T13948 T13950 nmod [,]
R9555 T13974 T13977 advmod Therefore,appears
R9556 T13949 T13950 nummod 6,]
R9557 T13950 T13947 appos ],sites
R9558 T13951 T13929 punct .,shown
R9559 T13952 T13956 prep In,binds
R9560 T13953 T13952 pobj addition,In
R9561 T13954 T13956 punct ",",binds
R9562 T13955 T13956 amod Sox6,binds
R9563 T13975 T13977 punct ",",appears
R9564 T13956 T13956 ROOT binds,binds
R9565 T13957 T13958 advmod more,strongly
R9566 T13958 T13959 advmod strongly,to
R9567 T13959 T13956 prep to,binds
R9568 T13976 T13977 nsubj it,appears
R9569 T13960 T13963 det an,motif
R9570 T13961 T13963 amod HMG-box,motif
R9571 T13962 T13963 compound dimer,motif
R9572 T13977 T13977 ROOT appears,appears
R9573 T13963 T13959 pobj motif,to
R9574 T13964 T13964 ROOT than,than
R9575 T13978 T13992 mark that,harbor
R9576 T13965 T13964 prep to,than
R9577 T13966 T13969 det a,motif
R9578 T13967 T13969 amod single,motif
R9579 T13979 T13980 compound target,genes
R9580 T13968 T13969 compound HMG-box,motif
R9581 T13969 T13965 pobj motif,to
R9582 T13970 T13956 advcl [,binds
R9583 T13980 T13992 nsubj genes,harbor
R9584 T13971 T13970 nummod 5,[
R9585 T13972 T13970 dobj ],[
R9586 T13973 T13956 punct .,binds
R9587 T13981 T13980 prep for,genes
R9588 T13982 T13985 nmod group,proteins
R9589 T13983 T13985 amod D,proteins
R9590 T13984 T13985 compound Sox,proteins
R9591 T13985 T13992 nsubj proteins,harbor
R9592 T14071 T14072 amod ɛy,promoter
R9593 T13986 T13985 punct ",",proteins
R9594 T14072 T14069 pobj promoter,of
R9595 T14073 T14074 preconj either,as
R9596 T14074 T14065 prep as,binds
R9597 T13987 T13988 amod such,as
R9598 T14075 T14076 det a,homodimer
R9599 T14076 T14074 pobj homodimer,as
R9600 T13988 T13985 prep as,proteins
R9601 T14077 T14074 cc or,as
R9602 T14078 T14074 conj as,as
R9603 T13989 T13988 pobj Sox6,as
R9604 T14079 T14080 det a,heterodimer
R9605 T14080 T14078 pobj heterodimer,as
R9606 T14081 T14080 prep with,heterodimer
R9607 T14082 T14084 amod other,proteins
R9608 T14083 T14084 compound Sox,proteins
R9609 T14084 T14081 pobj proteins,with
R9610 T13990 T13989 punct ",",Sox6
R9611 T14085 T14062 punct .,suggest
R9612 T14086 T14089 mark Because,recognize
R9613 T14087 T14088 compound Sox,proteins
R9614 T14088 T14089 nsubj proteins,recognize
R9615 T13991 T13992 advmod probably,harbor
R9616 T14089 T14107 advcl recognize,thought
R9617 T14090 T14094 det a,sequence
R9618 T13992 T13977 oprd harbor,appears
R9619 T14091 T14094 amod short,sequence
R9620 T14092 T14094 amod 6-bp,sequence
R9621 T14093 T14094 compound core-binding,sequence
R9622 T13993 T13992 dobj pairs,harbor
R9623 T14094 T14089 dobj sequence,recognize
R9624 T14095 T14096 nsubj that,allows
R9625 T14096 T14094 relcl allows,sequence
R9626 T13994 T13993 prep of,pairs
R9627 T14097 T14096 prep for,allows
R9628 T14098 T14099 amod considerable,degeneracy
R9629 T14099 T14097 pobj degeneracy,for
R9630 T13995 T13997 nmod HMG,sites
R9631 T14100 T14099 punct ",",degeneracy
R9632 T13996 T13997 amod binding,sites
R9633 T14101 T14102 det the,specificity
R9634 T14102 T14099 appos specificity,degeneracy
R9635 T14103 T14102 prep of,specificity
R9636 T13997 T13994 pobj sites,of
R9637 T14104 T14105 poss their,actions
R9638 T14105 T14103 pobj actions,of
R9639 T14106 T14107 auxpass is,thought
R9640 T13998 T13997 prep with,sites
R9641 T14107 T14107 ROOT thought,thought
R9642 T14108 T14109 aux to,rely
R9643 T13999 T14000 det a,configuration
R9644 T14109 T14107 xcomp rely,thought
R9645 T14110 T14109 prep upon,rely
R9646 T14111 T14110 pobj interactions,upon
R9647 T14000 T13998 pobj configuration,with
R9648 T14112 T14111 prep with,interactions
R9649 T14113 T14115 amod other,factors
R9650 T14114 T14115 compound transcription,factors
R9651 T14001 T14000 amod compatible,configuration
R9652 T14115 T14112 pobj factors,with
R9653 T14116 T14118 nmod [,]
R9654 T14002 T14001 prep with,compatible
R9655 T14117 T14118 nummod 36,]
R9656 T14118 T14115 appos ],factors
R9657 T14119 T14107 punct .,thought
R9658 T14120 T14125 prep In,had
R9659 T14121 T14122 poss our,EMSAs
R9660 T14122 T14120 pobj EMSAs,In
R9661 T14123 T14125 punct ",",had
R9662 T14003 T14002 pobj binding,with
R9663 T14124 T14125 nsubj we,had
R9664 T14125 T14125 ROOT had,had
R9665 T14004 T14003 prep of,binding
R9666 T14126 T14127 aux to,run
R9667 T14127 T14125 xcomp run,had
R9668 T14128 T14129 det the,electrophoresis
R9669 T14129 T14127 dobj electrophoresis,run
R9670 T14005 T14007 amod D-Sox,dimers
R9671 T14130 T14127 prep on,run
R9672 T14131 T14133 det a,%
R9673 T14006 T14007 compound protein,dimers
R9674 T14132 T14133 nummod 4,%
R9675 T14133 T14136 nmod %,gel
R9676 T14134 T14135 nummod 6,%
R9677 T14007 T14004 pobj dimers,of
R9678 T14135 T14136 compound %,gel
R9679 T14008 T13977 punct .,appears
R9680 T14009 T14025 advmod Indeed,contains
R9681 T14136 T14130 pobj gel,on
R9682 T14137 T14127 prep for,run
R9683 T14010 T14025 punct ",",contains
R9684 T14138 T14139 advmod at,least
R9685 T14139 T14140 advmod least,4
R9686 T14011 T14025 prep in,contains
R9687 T14140 T14137 pobj 4,for
R9688 T14141 T14142 nummod 8,h
R9689 T14142 T14140 appos h,4
R9690 T14012 T14014 det the,study
R9691 T14143 T14144 aux to,detect
R9692 T14144 T14127 advcl detect,run
R9693 T14013 T14014 amod present,study
R9694 T14014 T14011 pobj study,in
R9695 T14015 T14025 punct ",",contains
R9696 T14145 T14147 det the,band
R9697 T14146 T14147 amod Sox6-associated,band
R9698 T14016 T14020 det the,sequence
R9699 T14147 T14144 dobj band,detect
R9700 T14017 T14020 amod defined,sequence
R9701 T14148 T14125 punct ",",had
R9702 T14149 T14125 advcl suggesting,had
R9703 T14150 T14152 mark that,is
R9704 T14151 T14152 nsubj Sox6,is
R9705 T14018 T14020 compound Sox6,sequence
R9706 T14152 T14149 ccomp is,suggesting
R9707 T14153 T14152 attr part,is
R9708 T14154 T14153 prep of,part
R9709 T14155 T14159 det a,complex
R9710 T14156 T14158 amod high,weight
R9711 T14019 T14020 compound target,sequence
R9712 T14157 T14158 amod molecular,weight
R9713 T14158 T14159 compound weight,complex
R9714 T14159 T14154 pobj complex,of
R9715 T14020 T14025 nsubj sequence,contains
R9716 T14160 T14125 punct .,had
R9717 T14161 T14166 det A,repressors
R9718 T14162 T14166 amod few,repressors
R9719 T14021 T14020 prep of,sequence
R9720 T14163 T14166 amod other,repressors
R9721 T14164 T14166 amod ɛy,repressors
R9722 T14022 T14024 det the,promoter
R9723 T14165 T14166 compound globin,repressors
R9724 T14166 T14169 nsubjpass repressors,reported
R9725 T14167 T14169 aux have,reported
R9726 T14168 T14169 auxpass been,reported
R9727 T14023 T14024 amod ɛy,promoter
R9728 T14169 T14169 ROOT reported,reported
R9729 T14170 T14171 aux to,bind
R9730 T14024 T14021 pobj promoter,of
R9731 T14171 T14169 xcomp bind,reported
R9732 T14025 T14025 ROOT contains,contains
R9733 T14026 T14029 nummod two,sites
R9734 T14027 T14029 amod Sox/Sox6,sites
R9735 T14028 T14029 compound consensus,sites
R9736 T14172 T14171 prep to,bind
R9737 T14029 T14025 dobj sites,contains
R9738 T14173 T14174 compound DNA,sequences
R9739 T14174 T14172 pobj sequences,to
R9740 T14175 T14174 prep near,sequences
R9741 T14030 T14029 punct (,sites
R9742 T14176 T14179 det the,sites
R9743 T14177 T14179 compound Sox/Sox6,sites
R9744 T14031 T14032 compound Figure,3A
R9745 T14178 T14179 compound consensus,sites
R9746 T14179 T14175 pobj sites,near
R9747 T14180 T14179 punct ",",sites
R9748 T14032 T14029 appos 3A,sites
R9749 T14181 T14179 prep including,sites
R9750 T14182 T14187 det the,]
R9751 T14183 T14187 nmod DRED,]
R9752 T14033 T14029 punct ),sites
R9753 T14184 T14187 amod complex,]
R9754 T14185 T14187 nmod [,]
R9755 T14034 T14025 punct .,contains
R9756 T14186 T14187 nummod 37,]
R9757 T14187 T14181 pobj ],including
R9758 T14035 T14039 advmod Functionally,are
R9759 T14188 T14187 cc and,]
R9760 T14189 T14190 compound COUP-TF,[
R9761 T14190 T14187 conj [,]
R9762 T14191 T14192 nummod 38,]
R9763 T14192 T14187 conj ],]
R9764 T14036 T14039 punct ",",are
R9765 T14193 T14169 punct .,reported
R9766 T14194 T14196 nsubj Sox6,interact
R9767 T14195 T14196 aux might,interact
R9768 T14196 T14196 ROOT interact,interact
R9769 T14037 T14038 det both,sites
R9770 T14197 T14196 prep with,interact
R9771 T14198 T14199 det these,factors
R9772 T14038 T14039 nsubj sites,are
R9773 T14199 T14197 pobj factors,with
R9774 T14200 T14196 cc and,interact
R9775 T14201 T14196 conj form,interact
R9776 T14039 T14039 ROOT are,are
R9777 T14202 T14205 det a,complex
R9778 T14203 T14205 amod large,complex
R9779 T14204 T14205 compound repression,complex
R9780 T14040 T14039 acomp essential,are
R9781 T14205 T14201 dobj complex,form
R9782 T14206 T14196 punct .,interact
R9783 T14207 T14215 nsubjpass Identification,associated
R9784 T14041 T14040 prep for,essential
R9785 T14208 T14207 prep of,Identification
R9786 T14209 T14210 amod other,components
R9787 T14210 T14208 pobj components,of
R9788 T14042 T14043 amod Sox6,binding
R9789 T14211 T14210 prep of,components
R9790 T14212 T14215 det the,associated
R9791 T14213 T14215 amod Sox6-containing,associated
R9792 T14043 T14041 amod binding,for
R9793 T14044 T14043 prep to,binding
R9794 T14045 T14047 det the,promoter
R9795 T14214 T14215 amod complex,associated
R9796 T14046 T14047 amod ɛy,promoter
R9797 T14215 T14215 ROOT associated,associated
R9798 T14216 T14215 prep with,associated
R9799 T14217 T14219 det the,promoter
R9800 T14047 T14044 pobj promoter,to
R9801 T14218 T14219 amod ɛy,promoter
R9802 T14219 T14216 pobj promoter,with
R9803 T14220 T14221 aux will,shed
R9804 T14048 T14047 cc and,promoter
R9805 T14221 T14215 conj shed,associated
R9806 T14222 T14221 dobj light,shed
R9807 T14223 T14221 prep on,shed
R9808 T14049 T14047 conj repression,promoter
R9809 T14224 T14225 poss its,mechanism
R9810 T14050 T14047 prep of,promoter
R9811 T14225 T14223 pobj mechanism,on
R9812 T14226 T14225 prep of,mechanism
R9813 T14227 T14226 pobj repression,of
R9814 T14228 T14215 punct .,associated
R9815 T14051 T14052 poss its,activity
R9816 T14229 T14230 compound Sox,proteins
R9817 T14230 T14231 nsubj proteins,bind
R9818 T14052 T14050 pobj activity,of
R9819 T14231 T14231 ROOT bind,bind
R9820 T14232 T14231 cc and,bind
R9821 T14233 T14231 conj bend,bind
R9822 T14053 T14054 punct (,Figure
R9823 T14234 T14235 compound linear,DNA
R9824 T14235 T14233 dobj DNA,bend
R9825 T14236 T14233 prep by,bend
R9826 T14054 T14047 appos Figure,promoter
R9827 T14237 T14238 amod partial,intercalation
R9828 T14238 T14236 pobj intercalation,by
R9829 T14239 T14233 prep in,bend
R9830 T14055 T14054 nummod 3E,Figure
R9831 T14240 T14242 det the,groove
R9832 T14241 T14242 amod minor,groove
R9833 T14242 T14239 pobj groove,in
R9834 T14056 T14054 cc and,Figure
R9835 T14243 T14233 punct ",",bend
R9836 T14244 T14233 cc and,bend
R9837 T14245 T14247 aux can,bind
R9838 T14057 T14054 conj 3F,Figure
R9839 T14246 T14247 advmod also,bind
R9840 T14247 T14231 conj bind,bind
R9841 T14248 T14247 prep to,bind
R9842 T14058 T14039 punct ),are
R9843 T14249 T14250 amod four-way,junctions
R9844 T14250 T14248 pobj junctions,to
R9845 T14251 T14231 conj [,bind
R9846 T14059 T14039 punct .,are
R9847 T14252 T14251 nummod 2,[
R9848 T14253 T14254 nummod 4,]
R9849 T14254 T14251 appos ],[
R9850 T14060 T14061 det These,observations
R9851 T14255 T14251 punct .,[
R9852 T14256 T14269 advmod Therefore,is
R9853 T14257 T14269 punct ",",is
R9854 T14061 T14062 nsubj observations,suggest
R9855 T14258 T14260 nummod one,model
R9856 T14259 T14260 amod attractive,model
R9857 T14260 T14269 nsubj model,is
R9858 T14062 T14062 ROOT suggest,suggest
R9859 T14261 T14262 aux to,explain
R9860 T14262 T14260 relcl explain,model
R9861 T14263 T14266 advmod how,control
R9862 T14264 T14266 acomp Sox6,control
R9863 T14265 T14266 nsubj proteins,control
R9864 T14063 T14065 mark that,binds
R9865 T14266 T14268 compound control,expression
R9866 T14267 T14268 compound gene,expression
R9867 T14268 T14262 dobj expression,explain
R9868 T14064 T14065 amod Sox6,binds
R9869 T14065 T14062 ccomp binds,suggest
R9870 T14066 T14065 prep to,binds
R9871 T14067 T14068 det this,sequence
R9872 T14269 T14269 ROOT is,is
R9873 T14270 T14272 mark that,function
R9874 T14271 T14272 nsubj they,function
R9875 T14272 T14269 ccomp function,is
R9876 T14068 T14066 pobj sequence,to
R9877 T14273 T14272 prep as,function
R9878 T14274 T14275 amod architectural,factors
R9879 T14275 T14273 pobj factors,as
R9880 T14069 T14068 prep of,sequence
R9881 T14276 T14275 acl bound,factors
R9882 T14277 T14276 prep to,bound
R9883 T14070 T14072 det the,promoter
R9884 T14278 T14277 pobj DNA,to
R9885 T14279 T14272 punct ",",function
R9886 T14280 T14272 advcl influencing,function
R9887 T14366 T14365 prep of,family
R9888 T14281 T14283 amod local,structure
R9889 T14367 T14368 compound transcription,factors
R9890 T14282 T14283 compound chromatin,structure
R9891 T14283 T14280 dobj structure,influencing
R9892 T14284 T14280 prep by,influencing
R9893 T14285 T14284 pcomp bending,by
R9894 T14368 T14366 pobj factors,of
R9895 T14286 T14285 dobj DNA,bending
R9896 T14287 T14284 cc and,by
R9897 T14288 T14284 conj by,by
R9898 T14369 T14365 punct ),family
R9899 T14289 T14288 pcomp assembling,by
R9900 T14290 T14292 amod multiprotein,complexes
R9901 T14291 T14292 amod transcriptional,complexes
R9902 T14370 T14365 punct ",",family
R9903 T14292 T14289 dobj complexes,assembling
R9904 T14293 T14269 punct .,is
R9905 T14294 T14304 prep By,interfere
R9906 T14371 T14365 appos HMG-I,family
R9907 T14295 T14294 pcomp changing,By
R9908 T14296 T14299 det the,structure
R9909 T14297 T14299 amod local,structure
R9910 T14298 T14299 compound chromatin,structure
R9911 T14299 T14295 dobj structure,changing
R9912 T14300 T14304 punct ",",interfere
R9913 T14372 T14371 cc and,HMG-I
R9914 T14301 T14304 nsubj Sox6,interfere
R9915 T14302 T14304 aux could,interfere
R9916 T14373 T14371 conj HMG-Y,HMG-I
R9917 T14303 T14304 preconj either,interfere
R9918 T14374 T14376 punct ",",demonstrated
R9919 T14304 T14304 ROOT interfere,interfere
R9920 T14305 T14304 prep with,interfere
R9921 T14375 T14376 auxpass were,demonstrated
R9922 T14306 T14305 pobj binding,with
R9923 T14307 T14306 prep of,binding
R9924 T14308 T14309 amod other,activators
R9925 T14376 T14376 ROOT demonstrated,demonstrated
R9926 T14309 T14307 pobj activators,of
R9927 T14310 T14309 prep to,activators
R9928 T14311 T14312 det the,promoter
R9929 T14377 T14378 aux to,bind
R9930 T14312 T14310 pobj promoter,to
R9931 T14313 T14304 cc or,interfere
R9932 T14378 T14376 xcomp bind,demonstrated
R9933 T14314 T14304 conj facilitate,interfere
R9934 T14315 T14314 dobj binding,facilitate
R9935 T14379 T14378 prep to,bind
R9936 T14316 T14315 prep of,binding
R9937 T14317 T14318 amod other,repressors
R9938 T14318 T14316 pobj repressors,of
R9939 T14380 T14385 det the,silencers
R9940 T14319 T14304 punct .,interfere
R9941 T14320 T14321 det Another,example
R9942 T14321 T14334 nsubj example,is
R9943 T14381 T14382 amod human,adult
R9944 T14322 T14321 prep of,example
R9945 T14323 T14324 det a,repressor
R9946 T14324 T14322 pobj repressor,of
R9947 T14382 T14385 nmod adult,silencers
R9948 T14325 T14326 nsubj that,interferes
R9949 T14326 T14324 relcl interferes,repressor
R9950 T14327 T14326 prep with,interferes
R9951 T14328 T14329 det an,activator
R9952 T14329 T14327 pobj activator,with
R9953 T14330 T14329 prep on,activator
R9954 T14383 T14385 nmod β,silencers
R9955 T14331 T14333 det the,promoter
R9956 T14332 T14333 amod ɛy,promoter
R9957 T14333 T14330 pobj promoter,on
R9958 T14384 T14385 compound globin,silencers
R9959 T14334 T14334 ROOT is,is
R9960 T14335 T14334 attr DRED,is
R9961 T14336 T14334 punct .,is
R9962 T14337 T14338 nsubj DRED,interferes
R9963 T14338 T14338 ROOT interferes,interferes
R9964 T14339 T14338 prep with,interferes
R9965 T14385 T14379 pobj silencers,to
R9966 T14340 T14339 pobj EKLF,with
R9967 T14341 T14340 punct ",",EKLF
R9968 T14342 T14343 det an,activator
R9969 T14386 T14385 punct (,silencers
R9970 T14343 T14340 appos activator,EKLF
R9971 T14344 T14340 punct ",",EKLF
R9972 T14345 T14338 prep in,interferes
R9973 T14346 T14345 amod binding,in
R9974 T14387 T14385 appos silencers,silencers
R9975 T14347 T14346 prep to,binding
R9976 T14348 T14350 det the,promoter
R9977 T14349 T14350 amod ɛy,promoter
R9978 T14388 T14387 advmod I,silencers
R9979 T14350 T14347 pobj promoter,to
R9980 T14351 T14350 appos [,promoter
R9981 T14352 T14353 nummod 39,]
R9982 T14389 T14388 cc and,I
R9983 T14353 T14350 appos ],promoter
R9984 T14354 T14338 punct .,interferes
R9985 T14355 T14358 nummod Two,proteins
R9986 T14390 T14388 conj II,I
R9987 T14356 T14358 nmod HMG,proteins
R9988 T14357 T14358 amod architectural,proteins
R9989 T14358 T14376 nsubjpass proteins,demonstrated
R9990 T14391 T14388 punct ),I
R9991 T14359 T14358 punct (,proteins
R9992 T14360 T14361 advmod distantly,related
R9993 T14361 T14358 acl related,proteins
R9994 T14362 T14361 prep to,related
R9995 T14392 T14378 cc and,bind
R9996 T14363 T14365 det the,family
R9997 T14364 T14365 compound Sox,family
R9998 T14365 T14362 pobj family,to
R9999 T14393 T14378 conj cause,bind