PMC:1134658 / 11508-22156 JSONTXT 18 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10324 11-17 JJ denotes Recent
T10325 18-25 NNS denotes studies
T10326 26-30 VBP denotes have
T10327 31-43 VBN denotes demonstrated
T10328 44-46 DT denotes an
T10329 47-56 JJ denotes important
T10330 57-61 NN denotes role
T10331 62-65 IN denotes for
T10332 66-69 NN denotes BMP
T10333 70-81 RB denotes superfamily
T10334 82-89 NNS denotes members
T10335 90-92 IN denotes in
T10336 93-106 JJ denotes hematopoietic
T10337 107-111 NN denotes stem
T10338 112-117 NNS denotes cells
T10339 117-118 , denotes ,
T10340 119-124 JJ denotes early
T10341 125-135 NNS denotes thymocytes
T10342 136-137 NNP denotes [
T10343 137-140 CD denotes 6,7
T10344 140-141 NNP denotes ]
T10345 142-145 CC denotes and
T10346 146-152 NNP denotes B-cell
T10347 153-165 NNS denotes malignancies
T10348 166-167 NNP denotes [
T10349 167-174 CD denotes 8,11,12
T10350 174-175 NNP denotes ]
T10351 175-176 , denotes ,
T10352 177-180 CC denotes but
T10353 181-182 DT denotes a
T10354 183-187 NN denotes role
T10355 188-191 IN denotes for
T10356 192-196 NNS denotes BMPs
T10357 197-199 IN denotes in
T10358 200-206 JJ denotes normal
T10359 207-212 JJ denotes human
T10360 213-214 NNP denotes B
T10361 215-220 NNS denotes cells
T10362 221-224 VBZ denotes has
T10363 225-235 RB denotes previously
T10364 236-239 RB denotes not
T10365 240-244 VBN denotes been
T10366 245-253 VBN denotes reported
T10367 253-254 . denotes .
T10368 255-258 DT denotes The
T10369 259-266 JJ denotes present
T10370 267-272 NN denotes study
T10371 273-285 VBD denotes demonstrated
T10372 286-287 DT denotes a
T10373 288-299 JJ denotes significant
T10374 300-317 JJ denotes antiproliferative
T10375 318-324 NN denotes effect
T10376 325-327 IN denotes of
T10377 328-333 NN denotes BMP-6
T10378 334-336 IN denotes in
T10379 337-347 JJ denotes peripheral
T10380 348-353 NN denotes blood
T10381 354-358 NNP denotes CD19
T10382 358-359 NNP denotes +
T10383 360-361 NNP denotes B
T10384 362-367 NNS denotes cells
T10385 367-368 . denotes .
T10386 369-381 RB denotes Additionally
T10387 381-382 , denotes ,
T10388 383-388 NNP denotes BMP-6
T10389 389-396 VBD denotes induced
T10390 397-401 NN denotes cell
T10391 402-407 NN denotes death
T10392 408-410 IN denotes in
T10393 411-415 NNP denotes CD27
T10394 415-416 NNP denotes +
T10395 417-423 NN denotes memory
T10396 424-425 NNP denotes B
T10397 426-431 NNS denotes cells
T10398 432-434 RB denotes as
T10399 435-439 RB denotes well
T10400 440-442 IN denotes as
T10401 443-445 IN denotes in
T10402 446-447 DT denotes a
T10403 448-455 NNP denotes Burkitt
T10404 456-464 NN denotes lymphoma
T10405 465-469 NN denotes cell
T10406 470-474 NN denotes line
T10407 475-476 -LRB- denotes (
T10408 476-481 NNP denotes Ramos
T10409 481-482 -RRB- denotes )
T10410 482-483 . denotes .
T10411 484-495 RB denotes Importantly
T10412 495-496 , denotes ,
T10413 497-502 NNP denotes BMP-6
T10414 503-510 VBD denotes induced
T10415 511-512 DT denotes a
T10416 513-518 JJ denotes rapid
T10417 519-522 CC denotes and
T10418 523-529 JJ denotes marked
T10419 530-538 NN denotes increase
T10420 539-541 IN denotes in
T10421 542-548 NNP denotes Smad-1
T10422 548-549 CD denotes /
T10423 549-552 CD denotes 5/8
T10424 553-568 NN denotes phosphorylation
T10425 568-569 . denotes .
T10426 570-581 RB denotes Furthermore
T10427 581-582 , denotes ,
T10428 583-586 DT denotes the
T10429 587-592 NNP denotes BMP-6
T10430 593-600 VBD denotes induced
T10431 601-605 NNP denotes Smad
T10432 606-621 NN denotes phosphorylation
T10433 622-625 VBD denotes was
T10434 626-634 VBN denotes followed
T10435 635-637 IN denotes by
T10436 638-639 DT denotes a
T10437 640-649 JJ denotes selective
T10438 650-662 NN denotes upregulation
T10439 663-665 IN denotes of
T10440 666-669 NNP denotes Id1
T10441 670-674 NNP denotes mRNA
T10442 675-678 CC denotes and
T10443 679-689 JJ denotes subsequent
T10444 690-693 JJ denotes Id1
T10445 694-701 NN denotes protein
T10446 701-702 . denotes .
T10447 703-705 IN denotes In
T10448 706-709 DT denotes the
T10449 710-717 JJ denotes present
T10450 718-723 NN denotes study
T10451 723-724 , denotes ,
T10452 725-728 DT denotes the
T10453 729-741 VBN denotes demonstrated
T10454 742-759 JJ denotes antiproliferative
T10455 760-766 NN denotes effect
T10456 767-769 IN denotes of
T10457 770-775 NN denotes BMP-6
T10458 776-778 IN denotes in
T10459 779-787 JJ denotes anti-IgM
T10460 788-795 VBN denotes treated
T10461 796-797 NNP denotes B
T10462 798-803 NNS denotes cells
T10463 804-807 VBD denotes was
T10464 808-819 JJ denotes significant
T10465 820-823 CC denotes and
T10466 824-838 JJ denotes dose-dependent
T10467 838-839 . denotes .
T10468 840-851 RB denotes Importantly
T10469 851-852 , denotes ,
T10470 853-856 DT denotes the
T10471 857-875 JJ denotes anti-proliferative
T10472 876-882 NN denotes effect
T10473 883-885 IN denotes of
T10474 886-891 NN denotes BMP-6
T10475 892-897 MD denotes could
T10476 898-900 VB denotes be
T10477 901-911 RB denotes completely
T10478 912-923 VBN denotes neutralized
T10479 924-926 IN denotes by
T10480 927-930 DT denotes the
T10481 931-934 NN denotes use
T10482 935-937 IN denotes of
T10483 938-939 DT denotes a
T10484 940-947 JJ denotes natural
T10485 948-957 NN denotes inhibitor
T10486 957-958 , denotes ,
T10487 959-965 NNP denotes Noggin
T10488 965-966 . denotes .
T10489 967-971 DT denotes This
T10490 972-974 VBZ denotes is
T10491 975-977 IN denotes in
T10492 978-982 NN denotes line
T10493 983-987 IN denotes with
T10494 988-994 NNS denotes others
T10495 994-995 , denotes ,
T10496 996-1003 VBG denotes showing
T10497 1004-1008 IN denotes that
T10498 1009-1015 NNP denotes Noggin
T10499 1016-1019 MD denotes can
T10500 1020-1028 VB denotes function
T10501 1029-1031 IN denotes as
T10502 1032-1033 DT denotes a
T10503 1034-1039 NN denotes BMP-6
T10504 1040-1050 NN denotes antagonist
T10505 1051-1052 NNP denotes [
T10506 1052-1057 CD denotes 21,22
T10507 1057-1058 NNP denotes ]
T10508 1058-1059 . denotes .
T10509 1060-1062 IN denotes In
T10510 1063-1071 NN denotes addition
T10511 1071-1072 , denotes ,
T10512 1073-1076 DT denotes the
T10513 1077-1088 NN denotes combination
T10514 1089-1091 IN denotes of
T10515 1092-1099 JJ denotes soluble
T10516 1100-1110 JJ denotes BMP-RIB-Fc
T10517 1111-1114 CC denotes and
T10518 1115-1125 JJ denotes BMP-RII-Fc
T10519 1126-1132 NN denotes fusion
T10520 1133-1141 NNS denotes proteins
T10521 1142-1146 RB denotes also
T10522 1147-1158 VBD denotes neutralized
T10523 1159-1162 DT denotes the
T10524 1163-1181 JJ denotes anti-proliferative
T10525 1182-1188 NN denotes effect
T10526 1189-1191 IN denotes of
T10527 1192-1197 NN denotes BMP-6
T10528 1198-1200 IN denotes in
T10529 1201-1206 JJ denotes human
T10530 1207-1208 NNP denotes B
T10531 1209-1214 NNS denotes cells
T10532 1214-1215 . denotes .
T10533 1216-1229 RB denotes Interestingly
T10534 1229-1230 , denotes ,
T10535 1231-1233 IN denotes as
T10536 1234-1237 IN denotes for
T10537 1238-1243 JJ denotes other
T10538 1244-1247 NNP denotes TGF
T10539 1248-1254 NN denotes family
T10540 1255-1262 NNS denotes members
T10541 1262-1263 , denotes ,
T10542 1264-1276 JJ denotes bifunctional
T10543 1277-1284 NNS denotes effects
T10544 1285-1289 VBP denotes have
T10545 1290-1294 RB denotes also
T10546 1295-1299 VBN denotes been
T10547 1300-1312 VBN denotes demonstrated
T10548 1313-1316 IN denotes for
T10549 1317-1321 NNS denotes BMPs
T10550 1321-1322 . denotes .
T10551 1323-1330 IN denotes Whereas
T10552 1331-1338 JJ denotes several
T10553 1339-1341 IN denotes of
T10554 1342-1345 DT denotes the
T10555 1346-1350 NNS denotes BMPs
T10556 1351-1355 VBP denotes have
T10557 1356-1360 VBN denotes been
T10558 1361-1366 VBN denotes shown
T10559 1367-1369 TO denotes to
T10560 1370-1377 VB denotes promote
T10561 1378-1391 NN denotes proliferation
T10562 1392-1394 IN denotes in
T10563 1395-1402 JJ denotes various
T10564 1403-1407 NN denotes cell
T10565 1408-1413 NNS denotes types
T10566 1414-1423 VBG denotes including
T10567 1424-1435 NNS denotes condrocytes
T10568 1436-1437 NNP denotes [
T10569 1437-1439 CD denotes 23
T10570 1439-1440 NNP denotes ]
T10571 1440-1441 , denotes ,
T10572 1442-1447 NN denotes liver
T10573 1448-1449 NNP denotes [
T10574 1449-1451 CD denotes 24
T10575 1451-1452 NNP denotes ]
T10576 1453-1456 CC denotes and
T10577 1457-1466 NN denotes granulosa
T10578 1467-1472 NNS denotes cells
T10579 1473-1474 NNP denotes [
T10580 1474-1476 CD denotes 25
T10581 1476-1477 NNP denotes ]
T10582 1477-1478 , denotes ,
T10583 1479-1496 JJ denotes antiproliferative
T10584 1497-1504 NNS denotes effects
T10585 1505-1508 CC denotes and
T10586 1509-1518 NN denotes induction
T10587 1519-1521 IN denotes of
T10588 1522-1531 NN denotes apoptosis
T10589 1532-1535 VBZ denotes has
T10590 1536-1540 VBN denotes been
T10591 1541-1549 VBN denotes reported
T10592 1550-1553 IN denotes for
T10593 1554-1555 NNP denotes B
T10594 1556-1559 CC denotes and
T10595 1560-1561 NNP denotes T
T10596 1562-1569 NN denotes lineage
T10597 1570-1575 NNS denotes cells
T10598 1575-1576 . denotes .
T10599 1577-1584 JJ denotes Similar
T10600 1585-1592 NNS denotes effects
T10601 1593-1595 IN denotes as
T10602 1596-1608 VBN denotes demonstrated
T10603 1609-1612 IN denotes for
T10604 1613-1618 NN denotes BMP-6
T10605 1619-1621 IN denotes on
T10606 1622-1627 JJ denotes human
T10607 1628-1629 NNP denotes B
T10608 1630-1635 NNS denotes cells
T10609 1636-1638 IN denotes in
T10610 1639-1642 DT denotes the
T10611 1643-1650 JJ denotes present
T10612 1651-1656 NN denotes study
T10613 1656-1657 , denotes ,
T10614 1658-1662 VBD denotes were
T10615 1663-1675 VBN denotes demonstrated
T10616 1676-1679 IN denotes for
T10617 1680-1685 NNP denotes BMP-2
T10618 1685-1686 , denotes ,
T10619 1687-1688 CD denotes 4
T10620 1688-1689 , denotes ,
T10621 1690-1691 CD denotes 6
T10622 1692-1695 CC denotes and
T10623 1696-1698 CD denotes -7
T10624 1699-1701 IN denotes in
T10625 1702-1707 JJ denotes human
T10626 1708-1715 NN denotes myeloma
T10627 1716-1721 NNS denotes cells
T10628 1722-1723 NNP denotes [
T10629 1723-1727 CD denotes 9-11
T10630 1727-1728 NNP denotes ]
T10631 1728-1729 . denotes .
T10632 1730-1735 JJ denotes Other
T10633 1736-1743 NNS denotes members
T10634 1744-1746 IN denotes of
T10635 1747-1750 DT denotes the
T10636 1751-1761 NNP denotes BMP-family
T10637 1762-1766 VBP denotes have
T10638 1767-1771 RB denotes also
T10639 1772-1776 VBN denotes been
T10640 1777-1785 VBN denotes reported
T10641 1786-1788 TO denotes to
T10642 1789-1795 VB denotes induce
T10643 1796-1805 NN denotes apoptosis
T10644 1805-1806 , denotes ,
T10645 1807-1816 VBG denotes including
T10646 1817-1819 IN denotes in
T10647 1820-1825 NN denotes mouse
T10648 1826-1827 NNP denotes B
T10649 1828-1835 NN denotes lineage
T10650 1836-1841 NNS denotes cells
T10651 1842-1843 NNP denotes [
T10652 1843-1845 CD denotes 26
T10653 1845-1846 NNP denotes ]
T10654 1846-1847 . denotes .
T10655 1848-1860 RB denotes Additionally
T10656 1860-1861 , denotes ,
T10657 1862-1867 JJ denotes BMP-4
T10658 1868-1876 NNS denotes inhibits
T10659 1877-1886 VBP denotes thymocyte
T10660 1887-1900 NN denotes proliferation
T10661 1901-1902 NN denotes [
T10662 1902-1903 CD denotes 6
T10663 1903-1904 NNP denotes ]
T10664 1904-1905 . denotes .
T10665 1906-1911 VBN denotes Taken
T10666 1912-1920 RB denotes together
T10667 1920-1921 , denotes ,
T10668 1922-1927 DT denotes these
T10669 1928-1932 NNS denotes data
T10670 1933-1940 VBP denotes suggest
T10671 1941-1945 IN denotes that
T10672 1946-1949 DT denotes the
T10673 1950-1954 NN denotes role
T10674 1955-1957 IN denotes of
T10675 1958-1962 NNS denotes BMPs
T10676 1963-1965 IN denotes in
T10677 1966-1969 DT denotes the
T10678 1970-1980 NN denotes regulation
T10679 1981-1983 IN denotes of
T10680 1984-1997 NN denotes proliferation
T10681 1998-2001 CC denotes and
T10682 2002-2011 NN denotes apoptosis
T10683 2012-2014 VBZ denotes is
T10684 2015-2021 RB denotes highly
T10685 2022-2026 NN denotes cell
T10686 2027-2031 NN denotes type
T10687 2032-2041 JJ denotes dependent
T10688 2041-2042 . denotes .
T10689 2043-2045 TO denotes To
T10690 2046-2053 VB denotes examine
T10691 2054-2057 WRB denotes how
T10692 2058-2063 JJ denotes BMP-6
T10693 2064-2070 VBZ denotes exerts
T10694 2071-2074 PRP$ denotes its
T10695 2075-2085 JJ denotes functional
T10696 2086-2093 NNS denotes effects
T10697 2094-2096 IN denotes in
T10698 2097-2098 NNP denotes B
T10699 2099-2104 NNS denotes cells
T10700 2104-2105 , denotes ,
T10701 2106-2108 PRP denotes we
T10702 2109-2117 VBD denotes analysed
T10703 2118-2121 NN denotes BMP
T10704 2122-2130 NN denotes receptor
T10705 2131-2141 NN denotes expression
T10706 2142-2144 IN denotes by
T10707 2145-2152 JJ denotes western
T10708 2153-2157 NN denotes blot
T10709 2158-2166 NN denotes analysis
T10710 2166-2167 . denotes .
T10711 2168-2173 NNP denotes Human
T10712 2174-2184 JJ denotes peripheral
T10713 2185-2186 NNP denotes B
T10714 2187-2192 NNS denotes cells
T10715 2193-2197 VBD denotes were
T10716 2198-2203 VBN denotes found
T10717 2204-2206 TO denotes to
T10718 2207-2214 VB denotes express
T10719 2215-2218 DT denotes the
T10720 2219-2222 NN denotes BMP
T10721 2223-2227 NN denotes type
T10722 2228-2229 PRP denotes I
T10723 2230-2239 NNS denotes receptors
T10724 2240-2247 NNP denotes Act-RIA
T10725 2248-2251 CC denotes and
T10726 2252-2259 NNP denotes BMP-RIB
T10727 2259-2260 , denotes ,
T10728 2261-2264 CC denotes and
T10729 2265-2268 DT denotes the
T10730 2269-2273 NN denotes type
T10731 2274-2286 NNS denotes II-receptors
T10732 2287-2294 NNP denotes BMP-RII
T10733 2295-2298 CC denotes and
T10734 2299-2307 NNP denotes Act-RIIb
T10735 2307-2308 , denotes ,
T10736 2309-2314 WDT denotes which
T10737 2315-2321 VBP denotes signal
T10738 2322-2327 IN denotes after
T10739 2328-2335 JJ denotes binding
T10740 2336-2338 IN denotes of
T10741 2339-2346 JJ denotes several
T10742 2347-2351 NNS denotes BMPs
T10743 2351-2352 , denotes ,
T10744 2353-2362 VBG denotes including
T10745 2363-2368 NNP denotes BMP-6
T10746 2369-2370 NNP denotes [
T10747 2370-2375 CD denotes 16,13
T10748 2375-2376 NNP denotes ]
T10749 2376-2377 . denotes .
T10750 2378-2380 TO denotes To
T10751 2381-2388 RBR denotes further
T10752 2389-2396 VB denotes explore
T10753 2397-2402 NNP denotes BMP-6
T10754 2403-2410 JJ denotes induced
T10755 2411-2421 NN denotes signalling
T10756 2421-2422 , denotes ,
T10757 2423-2433 NN denotes activation
T10758 2434-2436 IN denotes of
T10759 2437-2444 JJ denotes several
T10760 2445-2453 NNS denotes pathways
T10761 2454-2456 VBZ denotes is
T10762 2457-2465 JJ denotes possible
T10763 2465-2466 . denotes .
T10764 2467-2470 DT denotes The
T10765 2471-2476 JJ denotes major
T10766 2477-2487 JJ denotes signalling
T10767 2488-2495 NN denotes pathway
T10768 2496-2501 VBN denotes known
T10769 2502-2504 TO denotes to
T10770 2505-2509 NN denotes date
T10771 2509-2510 , denotes ,
T10772 2511-2513 VBZ denotes is
T10773 2514-2524 NN denotes activation
T10774 2525-2527 IN denotes of
T10775 2528-2535 NNS denotes R-Smads
T10776 2536-2537 NNP denotes [
T10777 2537-2542 CD denotes 13,27
T10778 2542-2543 NNP denotes ]
T10779 2543-2544 . denotes .
T10780 2545-2547 IN denotes In
T10781 2548-2552 DT denotes that
T10782 2553-2560 NN denotes respect
T10783 2560-2561 , denotes ,
T10784 2562-2566 NNS denotes BMPs
T10785 2567-2571 VBP denotes have
T10786 2572-2576 VBN denotes been
T10787 2577-2582 VBN denotes shown
T10788 2583-2585 TO denotes to
T10789 2586-2591 VB denotes exert
T10790 2592-2609 JJ denotes antiproliferative
T10791 2610-2617 NNS denotes effects
T10792 2618-2620 IN denotes in
T10793 2621-2622 NNP denotes B
T10794 2623-2630 NN denotes lineage
T10795 2631-2636 NNS denotes cells
T10796 2637-2640 IN denotes via
T10797 2641-2656 NN denotes phosphorylation
T10798 2657-2659 IN denotes of
T10799 2660-2666 JJ denotes R-Smad
T10800 2667-2668 NNP denotes [
T10801 2668-2673 CD denotes 11,28
T10802 2673-2674 NNP denotes ]
T10803 2674-2675 . denotes .
T10804 2676-2687 RB denotes Furthermore
T10805 2687-2688 , denotes ,
T10806 2689-2694 NN denotes BMP-2
T10807 2695-2698 VBZ denotes has
T10808 2699-2703 VBN denotes been
T10809 2704-2709 VBN denotes shown
T10810 2710-2712 TO denotes to
T10811 2713-2719 VB denotes induce
T10812 2720-2730 NN denotes activation
T10813 2731-2733 IN denotes of
T10814 2734-2739 CD denotes STAT3
T10815 2740-2742 IN denotes in
T10816 2743-2750 NN denotes myeloma
T10817 2751-2756 NNS denotes cells
T10818 2757-2758 VBP denotes [
T10819 2758-2759 CD denotes 9
T10820 2759-2760 NNP denotes ]
T10821 2760-2761 . denotes .
T10822 2762-2769 RB denotes However
T10823 2769-2770 , denotes ,
T10824 2771-2786 NN denotes phosphorylation
T10825 2787-2789 IN denotes of
T10826 2790-2796 NN denotes R-Smad
T10827 2797-2800 VBD denotes was
T10828 2801-2804 RB denotes not
T10829 2805-2817 VBN denotes investigated
T10830 2818-2820 IN denotes in
T10831 2821-2825 DT denotes that
T10832 2826-2831 NN denotes study
T10833 2831-2832 . denotes .
T10834 2833-2838 NN denotes BMP-2
T10835 2839-2842 VBZ denotes has
T10836 2843-2847 RB denotes also
T10837 2848-2852 VBN denotes been
T10838 2853-2858 VBN denotes shown
T10839 2859-2861 TO denotes to
T10840 2862-2868 VB denotes induce
T10841 2869-2884 NN denotes phosphorylation
T10842 2885-2887 IN denotes of
T10843 2888-2891 CD denotes p38
T10844 2892-2893 NNP denotes [
T10845 2893-2895 CD denotes 29
T10846 2895-2896 NNP denotes ]
T10847 2896-2897 . denotes .
T10848 2898-2902 RB denotes Thus
T10849 2902-2903 , denotes ,
T10850 2904-2919 NN denotes phosphorylation
T10851 2920-2922 IN denotes of
T10852 2923-2926 CD denotes p38
T10853 2926-2927 , denotes ,
T10854 2928-2933 CD denotes STAT3
T10855 2934-2937 CC denotes and
T10856 2938-2947 CD denotes Smad1/5/8
T10857 2948-2957 VBP denotes represent
T10858 2958-2967 JJ denotes important
T10859 2968-2982 JJ denotes BMP-signalling
T10860 2983-2991 NNS denotes pathways
T10861 2992-2996 WDT denotes that
T10862 2997-3005 VBD denotes mediated
T10863 3006-3009 DT denotes the
T10864 3010-3017 NNS denotes effects
T10865 3018-3020 IN denotes of
T10866 3021-3025 NNS denotes BMPs
T10867 3026-3029 CC denotes and
T10868 3030-3034 RB denotes even
T10869 3035-3045 JJ denotes cross-talk
T10870 3046-3053 IN denotes between
T10871 3054-3059 DT denotes these
T10872 3060-3068 NNS denotes pathways
T10873 3069-3072 VBZ denotes has
T10874 3073-3077 VBN denotes been
T10875 3078-3086 VBN denotes reported
T10876 3087-3088 NNP denotes [
T10877 3088-3093 CD denotes 29,30
T10878 3093-3094 NNP denotes ]
T10879 3094-3095 . denotes .
T10880 3096-3098 IN denotes In
T10881 3099-3102 DT denotes the
T10882 3103-3110 JJ denotes present
T10883 3111-3116 NN denotes study
T10884 3116-3117 , denotes ,
T10885 3118-3120 PRP denotes we
T10886 3121-3125 VBD denotes were
T10887 3126-3129 RB denotes not
T10888 3130-3134 JJ denotes able
T10889 3135-3137 TO denotes to
T10890 3138-3144 VB denotes detect
T10891 3145-3158 JJ denotes BMP-6-induced
T10892 3159-3166 NNS denotes changes
T10893 3167-3169 IN denotes in
T10894 3170-3173 DT denotes the
T10895 3174-3189 NN denotes phosphorylation
T10896 3190-3196 NN denotes status
T10897 3197-3199 IN denotes of
T10898 3200-3205 CD denotes STAT3
T10899 3206-3208 CC denotes or
T10900 3209-3212 CD denotes p38
T10901 3213-3215 IN denotes in
T10902 3216-3221 JJ denotes human
T10903 3222-3232 JJ denotes peripheral
T10904 3233-3234 NNP denotes B
T10905 3235-3240 NNS denotes cells
T10906 3240-3241 . denotes .
T10907 3242-3249 RB denotes Instead
T10908 3249-3250 , denotes ,
T10909 3251-3252 DT denotes a
T10910 3253-3258 JJ denotes rapid
T10911 3259-3262 CC denotes and
T10912 3263-3269 JJ denotes marked
T10913 3270-3285 NN denotes phosphorylation
T10914 3286-3288 IN denotes of
T10915 3289-3298 NNP denotes Smad1/5/8
T10916 3299-3302 VBD denotes was
T10917 3303-3311 VBN denotes revealed
T10918 3311-3312 . denotes .
T10919 3313-3315 IN denotes In
T10920 3316-3317 DT denotes a
T10921 3318-3326 JJ denotes parallel
T10922 3327-3332 NN denotes study
T10923 3332-3333 , denotes ,
T10924 3334-3336 PRP denotes we
T10925 3337-3341 VBP denotes have
T10926 3342-3347 VBN denotes found
T10927 3348-3352 IN denotes that
T10928 3353-3358 JJ denotes other
T10929 3359-3363 NNS denotes BMPs
T10930 3364-3368 RB denotes also
T10931 3369-3376 VBD denotes induced
T10932 3377-3392 NN denotes phosphorylation
T10933 3393-3395 IN denotes of
T10934 3396-3405 NNP denotes Smad1/5/8
T10935 3406-3408 IN denotes in
T10936 3409-3419 JJ denotes peripheral
T10937 3420-3421 NNP denotes B
T10938 3422-3427 NNS denotes cells
T10939 3428-3429 -LRB- denotes (
T10940 3429-3433 NNS denotes data
T10941 3434-3437 RB denotes not
T10942 3438-3443 VBN denotes shown
T10943 3443-3444 -RRB- denotes )
T10944 3444-3445 . denotes .
T10945 3446-3448 PRP denotes We
T10946 3449-3452 VBP denotes are
T10947 3453-3462 RB denotes currently
T10948 3463-3471 VBG denotes pursuing
T10949 3472-3482 NN denotes microarray
T10950 3483-3490 NNS denotes studies
T10951 3491-3493 TO denotes to
T10952 3494-3502 VB denotes identify
T10953 3503-3506 DT denotes the
T10954 3507-3517 JJ denotes signalling
T10955 3518-3526 NNS denotes pathways
T10956 3527-3530 CC denotes and
T10957 3531-3537 NN denotes target
T10958 3538-3543 NNS denotes genes
T10959 3544-3548 WDT denotes that
T10960 3549-3552 VBP denotes are
T10961 3553-3564 RB denotes differently
T10962 3565-3574 VBN denotes regulated
T10963 3575-3577 IN denotes by
T10964 3578-3581 DT denotes the
T10965 3582-3589 JJ denotes various
T10966 3590-3594 NNS denotes BMPs
T10967 3595-3597 IN denotes in
T10968 3598-3603 JJ denotes human
T10969 3604-3605 NNP denotes B
T10970 3606-3611 NNS denotes cells
T10971 3611-3612 . denotes .
T10972 3613-3625 NNP denotes Upregulation
T10973 3626-3628 IN denotes of
T10974 3629-3632 NNP denotes Id1
T10975 3633-3636 IN denotes via
T10976 3637-3646 NNP denotes Smad1/5/8
T10977 3647-3662 NN denotes phosphorylation
T10978 3663-3665 VBZ denotes is
T10979 3666-3667 DT denotes a
T10980 3668-3673 JJ denotes known
T10981 3674-3683 NN denotes mechanism
T10982 3684-3687 IN denotes for
T10983 3688-3693 NNP denotes BMP-6
T10984 3694-3704 VBG denotes signalling
T10985 3705-3707 IN denotes in
T10986 3708-3713 JJ denotes other
T10987 3714-3718 NN denotes cell
T10988 3719-3726 NNS denotes systems
T10989 3727-3728 NNP denotes [
T10990 3728-3733 CD denotes 31,32
T10991 3733-3734 NNP denotes ]
T10992 3735-3738 CC denotes and
T10993 3739-3749 NN denotes regulation
T10994 3750-3752 IN denotes of
T10995 3753-3764 NNS denotes Id-proteins
T10996 3765-3767 VBZ denotes is
T10997 3768-3775 VBN denotes thought
T10998 3776-3778 TO denotes to
T10999 3779-3781 VB denotes be
T11000 3782-3784 DT denotes an
T11001 3785-3794 JJ denotes important
T11002 3795-3804 NN denotes mechanism
T11003 3805-3808 IN denotes for
T11004 3809-3824 JJ denotes Smad-signalling
T11005 3825-3826 NNP denotes [
T11006 3826-3828 CD denotes 17
T11007 3828-3829 NNP denotes ]
T11008 3829-3830 . denotes .
T11009 3831-3833 IN denotes In
T11010 3834-3837 DT denotes the
T11011 3838-3845 JJ denotes present
T11012 3846-3851 NN denotes study
T11013 3851-3852 , denotes ,
T11014 3853-3862 JJ denotes real-time
T11015 3863-3869 NN denotes RT-PCR
T11016 3870-3881 NNS denotes experiments
T11017 3882-3890 VBD denotes revealed
T11018 3891-3892 DT denotes a
T11019 3893-3901 JJ denotes specific
T11020 3902-3911 RB denotes four-fold
T11021 3912-3924 NN denotes upregulation
T11022 3925-3928 IN denotes for
T11023 3929-3932 NNP denotes Id1
T11024 3933-3935 IN denotes in
T11025 3936-3949 NNP denotes BMP-6-treated
T11026 3950-3951 NNP denotes B
T11027 3952-3957 NNS denotes cells
T11028 3957-3958 , denotes ,
T11029 3959-3964 IN denotes while
T11030 3965-3968 DT denotes the
T11031 3969-3975 NN denotes amount
T11032 3976-3978 IN denotes of
T11033 3979-3982 NNP denotes Id2
T11034 3983-3986 JJ denotes Id4
T11035 3987-3995 VBD denotes remained
T11036 3996-4005 JJ denotes unchanged
T11037 4005-4006 . denotes .
T11038 4007-4009 IN denotes In
T11039 4010-4019 NN denotes agreement
T11040 4020-4024 IN denotes with
T11041 4025-4029 DT denotes this
T11042 4029-4030 , denotes ,
T11043 4031-4038 JJ denotes western
T11044 4039-4043 NN denotes blot
T11045 4044-4052 NN denotes analysis
T11046 4053-4065 VBD denotes demonstrated
T11047 4066-4068 DT denotes an
T11048 4069-4081 NN denotes upregulation
T11049 4082-4084 IN denotes of
T11050 4085-4088 JJ denotes Id1
T11051 4089-4096 NN denotes protein
T11052 4096-4097 , denotes ,
T11053 4098-4103 IN denotes while
T11054 4104-4107 DT denotes the
T11055 4108-4114 NN denotes amount
T11056 4115-4117 IN denotes of
T11057 4118-4121 NNP denotes Id2
T11058 4122-4125 CC denotes and
T11059 4126-4129 NNP denotes Id3
T11060 4130-4137 NN denotes protein
T11061 4138-4144 NNS denotes levels
T11062 4145-4153 VBD denotes remained
T11063 4154-4163 JJ denotes unchanged
T11064 4163-4164 . denotes .
T11065 4165-4175 RB denotes Previously
T11066 4175-4176 , denotes ,
T11067 4177-4180 NNP denotes Id1
T11068 4181-4184 VBZ denotes has
T11069 4185-4189 VBN denotes been
T11070 4190-4200 VBN denotes considered
T11071 4201-4204 RB denotes not
T11072 4205-4207 TO denotes to
T11073 4208-4210 VB denotes be
T11074 4211-4220 VBN denotes expressed
T11075 4221-4223 IN denotes in
T11076 4224-4229 JJ denotes later
T11077 4230-4243 JJ denotes developmental
T11078 4244-4250 NNS denotes stages
T11079 4251-4255 IN denotes than
T11080 4256-4261 JJ denotes pro-B
T11081 4262-4267 NNS denotes cells
T11082 4268-4269 NNP denotes [
T11083 4269-4274 CD denotes 33,34
T11084 4274-4275 NNP denotes ]
T11085 4275-4276 , denotes ,
T11086 4277-4280 CC denotes and
T11087 4281-4284 PRP$ denotes its
T11088 4285-4297 JJ denotes constitutive
T11089 4298-4308 NN denotes expression
T11090 4309-4312 VBZ denotes has
T11091 4313-4317 VBN denotes been
T11092 4318-4326 VBN denotes reported
T11093 4327-4329 TO denotes to
T11094 4330-4336 VB denotes impair
T11095 4337-4342 NN denotes mouse
T11096 4343-4344 NNP denotes B
T11097 4345-4349 NN denotes cell
T11098 4350-4361 NN denotes development
T11099 4362-4363 NNP denotes [
T11100 4363-4365 CD denotes 35
T11101 4365-4366 NNP denotes ]
T11102 4366-4367 . denotes .
T11103 4368-4377 RB denotes Therefore
T11104 4377-4378 , denotes ,
T11105 4379-4382 PRP$ denotes our
T11106 4383-4396 NN denotes demonstration
T11107 4397-4399 IN denotes of
T11108 4400-4403 DT denotes the
T11109 4404-4418 JJ denotes time-dependent
T11110 4419-4431 NN denotes upregulation
T11111 4432-4434 IN denotes of
T11112 4435-4438 NNP denotes Id1
T11113 4439-4443 NNP denotes mRNA
T11114 4444-4447 CC denotes and
T11115 4448-4455 NN denotes protein
T11116 4456-4458 IN denotes in
T11117 4459-4465 JJ denotes mature
T11118 4466-4472 JJ denotes normal
T11119 4473-4478 JJ denotes human
T11120 4479-4480 NNP denotes B
T11121 4481-4486 NNS denotes cells
T11122 4487-4489 VBZ denotes is
T11123 4490-4492 IN denotes of
T11124 4493-4503 JJ denotes particular
T11125 4504-4512 NN denotes interest
T11126 4512-4513 . denotes .
T11127 4514-4516 IN denotes In
T11128 4517-4521 DT denotes that
T11129 4522-4529 NN denotes respect
T11130 4529-4530 , denotes ,
T11131 4531-4533 PRP denotes it
T11132 4534-4536 VBZ denotes is
T11133 4537-4547 JJ denotes noteworthy
T11134 4548-4552 IN denotes that
T11135 4553-4558 JJ denotes TGF-β
T11136 4559-4569 NN denotes signalling
T11137 4570-4572 IN denotes in
T11138 4573-4578 JJ denotes early
T11139 4579-4582 CC denotes and
T11140 4583-4589 JJ denotes mature
T11141 4590-4591 NNP denotes B
T11142 4592-4597 NNS denotes cells
T11143 4598-4605 VBZ denotes induces
T11144 4606-4610 DT denotes both
T11145 4611-4614 JJ denotes Id2
T11146 4615-4618 CC denotes and
T11147 4619-4622 JJ denotes Id3
T11148 4623-4633 NN denotes expression
T11149 4634-4635 NNP denotes [
T11150 4635-4640 CD denotes 36,37
T11151 4640-4641 NNP denotes ]
T11152 4641-4642 , denotes ,
T11153 4643-4646 CC denotes but
T11154 4647-4650 RB denotes not
T11155 4651-4654 JJ denotes Id1
T11156 4655-4656 -LRB- denotes (
T11157 4656-4660 NNS denotes data
T11158 4661-4664 RB denotes not
T11159 4665-4670 VBN denotes shown
T11160 4670-4671 -RRB- denotes )
T11161 4671-4672 . denotes .
T11162 4673-4686 RB denotes Interestingly
T11163 4686-4687 , denotes ,
T11164 4688-4693 DT denotes these
T11165 4694-4701 NNS denotes results
T11166 4702-4706 VBP denotes show
T11167 4707-4711 IN denotes that
T11168 4712-4719 JJ denotes various
T11169 4720-4727 NNS denotes members
T11170 4728-4730 IN denotes of
T11171 4731-4734 DT denotes the
T11172 4735-4740 NNP denotes TGF-β
T11173 4741-4747 NN denotes family
T11174 4748-4756 VB denotes regulate
T11175 4757-4759 NN denotes Id
T11176 4760-4768 NNS denotes proteins
T11177 4769-4780 RB denotes differently
T11178 4780-4781 . denotes .
T11179 4782-4785 NNP denotes Id2
T11180 4786-4789 CC denotes and
T11181 4790-4793 NNP denotes Id3
T11182 4794-4797 VBP denotes are
T11183 4798-4808 VBN denotes considered
T11184 4809-4811 TO denotes to
T11185 4812-4814 VB denotes be
T11186 4815-4818 DT denotes the
T11187 4819-4821 NN denotes Id
T11188 4822-4830 VBZ denotes proteins
T11189 4831-4837 RB denotes mainly
T11190 4838-4847 VBN denotes expressed
T11191 4848-4850 IN denotes in
T11192 4851-4857 JJ denotes mature
T11193 4858-4859 NNP denotes B
T11194 4860-4865 NNS denotes cells
T11195 4866-4867 NNP denotes [
T11196 4867-4869 CD denotes 38
T11197 4869-4870 NNP denotes ]
T11198 4870-4871 . denotes .
T11199 4872-4875 DT denotes The
T11200 4876-4883 JJ denotes present
T11201 4884-4889 NN denotes study
T11202 4890-4894 RB denotes also
T11203 4895-4900 VBD denotes found
T11204 4901-4904 NNP denotes Id2
T11205 4905-4908 CC denotes and
T11206 4909-4912 NNP denotes Id3
T11207 4913-4920 NN denotes protein
T11208 4921-4923 IN denotes in
T11209 4924-4925 NNP denotes B
T11210 4926-4931 NNS denotes cells
T11211 4932-4934 TO denotes to
T11212 4935-4937 VB denotes be
T11213 4938-4942 RBR denotes more
T11214 4943-4949 RB denotes highly
T11215 4950-4959 VBN denotes expressed
T11216 4960-4964 IN denotes than
T11217 4965-4968 JJ denotes Id1
T11218 4969-4971 IN denotes in
T11219 4972-4979 VBG denotes resting
T11220 4980-4981 NNP denotes B
T11221 4982-4987 NNS denotes cells
T11222 4987-4988 . denotes .
T11223 4989-4996 RB denotes However
T11224 4996-4997 , denotes ,
T11225 4998-5003 NNP denotes BMP-6
T11226 5004-5007 VBD denotes did
T11227 5008-5011 RB denotes not
T11228 5012-5018 VB denotes induce
T11229 5019-5030 JJ denotes significant
T11230 5031-5038 NNS denotes changes
T11231 5039-5041 IN denotes in
T11232 5042-5045 DT denotes the
T11233 5046-5053 NN denotes protein
T11234 5054-5064 NN denotes expression
T11235 5065-5067 IN denotes of
T11236 5068-5071 NNP denotes Id2
T11237 5072-5075 CC denotes and
T11238 5076-5079 NNP denotes Id3
T11239 5079-5080 . denotes .
T11240 5081-5083 PRP denotes It
T11241 5084-5086 VBZ denotes is
T11242 5087-5095 VBN denotes believed
T11243 5096-5100 IN denotes that
T11244 5101-5103 NN denotes Id
T11245 5104-5112 NNS denotes proteins
T11246 5113-5118 VBP denotes block
T11247 5119-5134 NN denotes differentiation
T11248 5135-5138 CC denotes and
T11249 5139-5146 VB denotes promote
T11250 5147-5160 NN denotes proliferation
T11251 5161-5163 IN denotes in
T11252 5164-5171 JJ denotes various
T11253 5172-5176 NN denotes cell
T11254 5177-5182 NNS denotes types
T11255 5183-5184 NNP denotes [
T11256 5184-5189 CD denotes 39,33
T11257 5189-5190 NNP denotes ]
T11258 5190-5191 . denotes .
T11259 5192-5194 NN denotes Id
T11260 5195-5203 NNS denotes proteins
T11261 5204-5207 VBP denotes act
T11262 5208-5210 IN denotes as
T11263 5211-5228 JJ denotes dominant-negative
T11264 5229-5239 NNS denotes inhibitors
T11265 5240-5242 IN denotes of
T11266 5243-5253 NNS denotes E-proteins
T11267 5254-5257 CC denotes and
T11268 5258-5262 NNS denotes Pax5
T11269 5263-5271 NN denotes function
T11270 5272-5274 IN denotes by
T11271 5275-5282 VBG denotes forming
T11272 5283-5289 NNS denotes dimers
T11273 5290-5294 IN denotes with
T11274 5295-5300 DT denotes these
T11275 5301-5309 NNS denotes proteins
T11276 5309-5310 , denotes ,
T11277 5311-5317 VBG denotes making
T11278 5318-5322 PRP denotes them
T11279 5323-5329 JJ denotes unable
T11280 5330-5332 TO denotes to
T11281 5333-5337 NN denotes bind
T11282 5338-5341 NN denotes DNA
T11283 5341-5342 . denotes .
T11284 5343-5345 PRP denotes It
T11285 5346-5349 VBZ denotes has
T11286 5350-5354 VBN denotes been
T11287 5355-5363 VBN denotes proposed
T11288 5364-5368 IN denotes that
T11289 5369-5372 DT denotes the
T11290 5373-5380 NN denotes balance
T11291 5381-5386 IN denotes among
T11292 5387-5397 NNS denotes E-proteins
T11293 5397-5398 , denotes ,
T11294 5399-5403 NNS denotes Pax5
T11295 5404-5407 CC denotes and
T11296 5408-5410 NN denotes Id
T11297 5411-5419 NNS denotes proteins
T11298 5420-5425 MD denotes might
T11299 5426-5430 VB denotes have
T11300 5431-5433 DT denotes an
T11301 5434-5443 JJ denotes important
T11302 5444-5448 NN denotes role
T11303 5449-5451 IN denotes in
T11304 5452-5461 VBN denotes activated
T11305 5462-5463 NNP denotes B
T11306 5464-5469 NNS denotes cells
T11307 5470-5471 NNP denotes [
T11308 5471-5473 CD denotes 38
T11309 5473-5474 NNP denotes ]
T11310 5474-5475 . denotes .
T11311 5476-5478 IN denotes In
T11312 5479-5483 DT denotes that
T11313 5484-5491 NN denotes respect
T11314 5491-5492 , denotes ,
T11315 5493-5503 NNS denotes E-proteins
T11316 5504-5508 VBP denotes have
T11317 5509-5513 VBN denotes been
T11318 5514-5524 VBN denotes implicated
T11319 5525-5527 IN denotes in
T11320 5528-5532 DT denotes both
T11321 5533-5536 DT denotes the
T11322 5537-5546 NN denotes promotion
T11323 5547-5550 CC denotes and
T11324 5551-5561 NN denotes inhibition
T11325 5562-5564 IN denotes of
T11326 5565-5569 NN denotes cell
T11327 5570-5578 NN denotes survival
T11328 5579-5582 CC denotes and
T11329 5583-5589 NN denotes growth
T11330 5590-5592 IN denotes at
T11331 5593-5602 JJ denotes different
T11332 5603-5609 NNS denotes points
T11333 5610-5612 IN denotes in
T11334 5613-5623 NN denotes lymphocyte
T11335 5624-5635 NN denotes development
T11336 5636-5637 NNP denotes [
T11337 5637-5639 CD denotes 40
T11338 5639-5640 NNP denotes ]
T11339 5640-5641 . denotes .
T11340 5642-5645 DT denotes The
T11341 5646-5663 JJ denotes antiproliferative
T11342 5664-5667 CC denotes and
T11343 5668-5673 NN denotes death
T11344 5674-5682 VBG denotes inducing
T11345 5683-5689 NN denotes effect
T11346 5690-5692 IN denotes of
T11347 5693-5698 NN denotes BMP-6
T11348 5699-5701 IN denotes in
T11349 5702-5703 NNP denotes B
T11350 5704-5709 NNS denotes cells
T11351 5710-5714 IN denotes with
T11352 5715-5726 JJ denotes concomitant
T11353 5727-5739 NN denotes upregulation
T11354 5740-5742 IN denotes of
T11355 5743-5746 JJ denotes Id1
T11356 5747-5754 NN denotes protein
T11357 5755-5757 VBZ denotes is
T11358 5758-5767 RB denotes therefore
T11359 5768-5770 IN denotes in
T11360 5771-5775 NN denotes line
T11361 5776-5780 IN denotes with
T11362 5781-5784 DT denotes the
T11363 5785-5789 NN denotes view
T11364 5790-5794 IN denotes that
T11365 5795-5797 NN denotes Id
T11366 5798-5806 NNS denotes proteins
T11367 5807-5810 VBP denotes are
T11368 5811-5819 VBN denotes required
T11369 5820-5823 IN denotes for
T11370 5824-5827 DT denotes the
T11371 5828-5837 NN denotes induction
T11372 5838-5840 IN denotes of
T11373 5841-5847 NN denotes growth
T11374 5848-5854 NN denotes arrest
T11375 5855-5858 CC denotes and
T11376 5859-5868 NN denotes apoptosis
T11377 5869-5871 IN denotes in
T11378 5872-5884 JJ denotes B-lymphocyte
T11379 5885-5896 NNS denotes progenitors
T11380 5897-5899 IN denotes by
T11381 5900-5905 NNP denotes TGF-β
T11382 5906-5907 NNP denotes [
T11383 5907-5909 CD denotes 40
T11384 5909-5910 NNP denotes ]
T11385 5910-5911 . denotes .
T11386 5912-5923 RB denotes Furthermore
T11387 5923-5924 , denotes ,
T11388 5925-5927 NN denotes Id
T11389 5928-5936 NNS denotes proteins
T11390 5937-5940 VBP denotes are
T11391 5941-5946 VBN denotes known
T11392 5947-5949 IN denotes as
T11393 5950-5959 JJ denotes important
T11394 5960-5965 NNS denotes parts
T11395 5966-5968 IN denotes of
T11396 5969-5979 VBG denotes signalling
T11397 5980-5988 NNS denotes pathways
T11398 5989-5997 VBN denotes involved
T11399 5998-6000 IN denotes in
T11400 6001-6012 NN denotes development
T11401 6012-6013 , denotes ,
T11402 6014-6018 NN denotes cell
T11403 6019-6024 NN denotes cycle
T11404 6025-6028 CC denotes and
T11405 6029-6042 NN denotes tumorigenesis
T11406 6043-6044 NNP denotes [
T11407 6044-6046 CD denotes 32
T11408 6046-6047 NNP denotes ]
T11409 6047-6048 . denotes .
T11410 6049-6051 PRP denotes It
T11411 6052-6054 VBZ denotes is
T11412 6055-6059 RB denotes well
T11413 6060-6071 VBN denotes established
T11414 6072-6076 IN denotes that
T11415 6077-6084 JJ denotes various
T11416 6085-6092 NNS denotes members
T11417 6093-6095 IN denotes of
T11418 6096-6099 DT denotes the
T11419 6100-6102 NN denotes Id
T11420 6103-6109 NN denotes family
T11421 6110-6113 VBP denotes are
T11422 6114-6127 VBN denotes overexpressed
T11423 6128-6130 IN denotes in
T11424 6131-6132 DT denotes a
T11425 6133-6138 NN denotes range
T11426 6139-6141 IN denotes of
T11427 6142-6147 JJ denotes human
T11428 6148-6155 NNS denotes tumours
T11429 6156-6159 CC denotes and
T11430 6160-6169 RB denotes generally
T11431 6169-6170 , denotes ,
T11432 6171-6174 JJ denotes Id1
T11433 6175-6182 VBZ denotes appears
T11434 6183-6185 TO denotes to
T11435 6186-6188 VB denotes be
T11436 6189-6192 DT denotes the
T11437 6193-6199 NN denotes family
T11438 6200-6206 NN denotes member
T11439 6207-6211 RBS denotes most
T11440 6212-6218 RB denotes widely
T11441 6219-6232 VBN denotes overexpressed
T11442 6233-6235 IN denotes in
T11443 6236-6237 DT denotes a
T11444 6238-6245 NN denotes variety
T11445 6246-6248 IN denotes of
T11446 6249-6254 JJ denotes human
T11447 6255-6267 NNS denotes malignancies
T11448 6268-6269 NNP denotes [
T11449 6269-6271 CD denotes 41
T11450 6271-6272 NNP denotes ]
T11451 6272-6273 , denotes ,
T11452 6274-6283 VBG denotes including
T11453 6284-6292 JJ denotes multiple
T11454 6293-6300 NN denotes myeloma
T11455 6301-6302 NNP denotes [
T11456 6302-6307 CD denotes 42,32
T11457 6307-6308 NNP denotes ]
T11458 6308-6309 . denotes .
T11459 6310-6322 RB denotes Additionally
T11460 6322-6323 , denotes ,
T11461 6324-6327 PRP$ denotes our
T11462 6328-6336 NNS denotes findings
T11463 6337-6341 WDT denotes that
T11464 6342-6347 NNP denotes BMP-6
T11465 6348-6357 VBZ denotes activates
T11466 6358-6371 JJ denotes intracellular
T11467 6372-6382 JJ denotes signalling
T11468 6383-6391 NNS denotes pathways
T11469 6392-6394 IN denotes in
T11470 6395-6400 JJ denotes human
T11471 6401-6402 NNP denotes B
T11472 6403-6408 NNS denotes cells
T11473 6409-6414 MD denotes might
T11474 6415-6417 VB denotes be
T11475 6418-6420 IN denotes of
T11476 6421-6430 JJ denotes potential
T11477 6431-6449 JJ denotes pathophysiological
T11478 6450-6462 NN denotes significance
T11479 6463-6465 IN denotes in
T11480 6466-6474 NN denotes lymphoma
T11481 6475-6478 CC denotes and
T11482 6479-6491 NN denotes inflammation
T11483 6491-6492 . denotes .
T11484 6493-6497 NNP denotes High
T11485 6498-6503 NNP denotes BMP-6
T11486 6504-6508 NNP denotes mRNA
T11487 6509-6519 NN denotes expression
T11488 6520-6522 IN denotes in
T11489 6523-6528 NNP denotes DLBCL
T11490 6529-6532 VBZ denotes has
T11491 6533-6537 VBN denotes been
T11492 6538-6543 VBN denotes shown
T11493 6544-6546 TO denotes to
T11494 6547-6556 VB denotes correlate
T11495 6557-6559 TO denotes to
T11496 6560-6572 JJ denotes unfavourable
T11497 6573-6580 NN denotes outcome
T11498 6581-6582 NNP denotes [
T11499 6582-6584 CD denotes 12
T11500 6584-6585 NNP denotes ]
T11501 6585-6586 . denotes .
T11502 6587-6589 IN denotes In
T11503 6590-6594 DT denotes this
T11504 6595-6602 NN denotes respect
T11505 6602-6603 , denotes ,
T11506 6604-6606 PRP denotes it
T11507 6607-6609 VBZ denotes is
T11508 6610-6612 IN denotes of
T11509 6613-6621 NN denotes interest
T11510 6622-6626 IN denotes that
T11511 6627-6635 JJ denotes targeted
T11512 6636-6646 NN denotes expression
T11513 6647-6649 IN denotes of
T11514 6650-6653 NNP denotes Id1
T11515 6654-6656 TO denotes to
T11516 6657-6670 NNS denotes B-lymphocytes
T11517 6671-6679 VBD denotes resulted
T11518 6680-6682 IN denotes in
T11519 6683-6691 JJ denotes aberrant
T11520 6692-6693 NNP denotes B
T11521 6694-6698 NN denotes cell
T11522 6699-6710 NN denotes development
T11523 6710-6711 , denotes ,
T11524 6712-6719 JJ denotes massive
T11525 6720-6729 NN denotes apoptosis
T11526 6729-6730 , denotes ,
T11527 6731-6734 CC denotes and
T11528 6735-6745 JJ denotes subsequent
T11529 6746-6757 NN denotes development
T11530 6758-6760 IN denotes of
T11531 6761-6762 NNP denotes B
T11532 6763-6767 NN denotes cell
T11533 6768-6777 NNS denotes lymphomas
T11534 6778-6779 NNP denotes [
T11535 6779-6781 CD denotes 35
T11536 6781-6782 NNP denotes ]
T11537 6782-6783 . denotes .
T11538 6784-6792 RB denotes Moreover
T11539 6792-6793 , denotes ,
T11540 6794-6799 NNP denotes BMP-6
T11541 6800-6803 VBZ denotes has
T11542 6804-6808 VBN denotes been
T11543 6809-6818 VBN denotes suggested
T11544 6819-6821 TO denotes to
T11545 6822-6826 VB denotes play
T11546 6827-6828 DT denotes a
T11547 6829-6833 NN denotes role
T11548 6834-6836 IN denotes in
T11549 6837-6847 JJ denotes rheumatoid
T11550 6848-6857 NNS denotes arthritis
T11551 6858-6859 -LRB- denotes (
T11552 6859-6861 NNP denotes RA
T11553 6861-6862 -RRB- denotes )
T11554 6863-6864 NNP denotes [
T11555 6864-6869 CD denotes 43,44
T11556 6869-6870 NNP denotes ]
T11557 6871-6874 CC denotes and
T11558 6875-6883 JJ denotes elevated
T11559 6884-6890 NNS denotes levels
T11560 6891-6893 IN denotes of
T11561 6894-6897 NNP denotes Id1
T11562 6898-6901 CC denotes and
T11563 6902-6905 NNP denotes Id3
T11564 6906-6910 VBP denotes have
T11565 6911-6915 VBN denotes been
T11566 6916-6921 VBN denotes found
T11567 6922-6924 IN denotes in
T11568 6925-6928 DT denotes the
T11569 6929-6936 NN denotes synovia
T11570 6937-6939 IN denotes of
T11571 6940-6951 NNS denotes RA-patients
T11572 6952-6953 NNP denotes [
T11573 6953-6955 CD denotes 45
T11574 6955-6956 NNP denotes ]
T11575 6956-6957 . denotes .
T11576 6958-6968 RB denotes Altogether
T11577 6968-6969 , denotes ,
T11578 6970-6975 DT denotes these
T11579 6976-6983 NNS denotes results
T11580 6984-6989 NN denotes point
T11581 6990-6992 TO denotes to
T11582 6993-6995 DT denotes an
T11583 6996-7005 JJ denotes important
T11584 7006-7010 NN denotes role
T11585 7011-7014 IN denotes for
T11586 7015-7017 NN denotes Id
T11587 7018-7026 NNS denotes proteins
T11588 7027-7029 IN denotes in
T11589 7030-7033 DT denotes the
T11590 7034-7044 NN denotes regulation
T11591 7045-7047 IN denotes of
T11592 7048-7054 JJ denotes normal
T11593 7055-7056 NNP denotes B
T11594 7057-7061 NN denotes cell
T11595 7062-7073 NN denotes homeostasis
T11596 7074-7077 CC denotes and
T11597 7078-7080 IN denotes in
T11598 7081-7089 NNS denotes diseases
T11599 7089-7090 , denotes ,
T11600 7091-7096 WRB denotes where
T11601 7097-7098 NNP denotes B
T11602 7099-7104 NNS denotes cells
T11603 7105-7108 VBP denotes are
T11604 7109-7117 VBN denotes involved
T11605 7117-7118 . denotes .
T11606 7119-7121 PRP denotes It
T11607 7122-7126 MD denotes will
T11608 7127-7136 RB denotes therefore
T11609 7137-7139 VB denotes be
T11610 7140-7149 JJ denotes important
T11611 7150-7152 TO denotes to
T11612 7153-7160 RBR denotes further
T11613 7161-7170 VB denotes elucidate
T11614 7171-7174 DT denotes the
T11615 7175-7179 NN denotes role
T11616 7180-7182 IN denotes of
T11617 7183-7187 NN denotes Id-1
T11618 7188-7190 IN denotes in
T11619 7191-7196 JJ denotes human
T11620 7197-7198 NNP denotes B
T11621 7199-7204 NNS denotes cells
T11622 7205-7207 IN denotes by
T11623 7208-7217 JJ denotes selective
T11624 7218-7222 IN denotes over
T11625 7223-7233 NN denotes expression
T11626 7234-7236 CC denotes or
T11627 7237-7247 NN denotes inhibition
T11628 7248-7250 IN denotes of
T11629 7251-7255 JJ denotes Id-1
T11630 7256-7260 NN denotes gene
T11631 7261-7271 NN denotes expression
T11632 7271-7272 . denotes .
T11633 7273-7278 VBN denotes Given
T11634 7279-7282 DT denotes the
T11635 7283-7287 NN denotes role
T11636 7288-7290 IN denotes of
T11637 7291-7296 NNP denotes BMP-6
T11638 7297-7299 IN denotes in
T11639 7300-7306 NNP denotes mature
T11640 7307-7312 JJ denotes human
T11641 7313-7314 NNP denotes B
T11642 7315-7320 NNS denotes cells
T11643 7321-7333 VBD denotes demonstrated
T11644 7334-7338 RB denotes here
T11645 7338-7339 , denotes ,
T11646 7340-7354 NN denotes identification
T11647 7355-7357 IN denotes of
T11648 7358-7363 NNP denotes BMP-6
T11649 7364-7373 VBG denotes producing
T11650 7374-7379 NNS denotes cells
T11651 7380-7382 IN denotes in
T11652 7383-7387 NN denotes vivo
T11653 7388-7392 IN denotes with
T11654 7393-7404 NN denotes possibility
T11655 7405-7407 IN denotes of
T11656 7408-7419 NN denotes interaction
T11657 7420-7424 IN denotes with
T11658 7425-7430 NN denotes naïve
T11659 7431-7434 CC denotes and
T11660 7435-7441 NN denotes memory
T11661 7442-7443 NNP denotes B
T11662 7444-7449 NNS denotes cells
T11663 7450-7455 MD denotes might
T11664 7456-7466 VB denotes contribute
T11665 7467-7469 TO denotes to
T11666 7470-7473 DT denotes the
T11667 7474-7487 NN denotes understanding
T11668 7488-7490 IN denotes of
T11669 7491-7497 JJ denotes mature
T11670 7498-7499 NNP denotes B
T11671 7500-7504 NN denotes cell
T11672 7505-7512 NN denotes biology
T11673 7512-7513 . denotes .
T11674 7514-7518 NNP denotes High
T11675 7519-7524 NNP denotes BMP-6
T11676 7525-7529 NNP denotes mRNA
T11677 7530-7540 NN denotes expression
T11678 7541-7543 IN denotes in
T11679 7544-7549 NNP denotes DLBCL
T11680 7550-7553 VBZ denotes has
T11681 7554-7558 VBN denotes been
T11682 7559-7567 VBN denotes detected
T11683 7568-7570 IN denotes by
T11684 7571-7575 NN denotes gene
T11685 7576-7586 NN denotes expression
T11686 7587-7596 VBG denotes profiling
T11687 7597-7598 NNP denotes [
T11688 7598-7600 CD denotes 12
T11689 7600-7601 NNP denotes ]
T11690 7601-7602 . denotes .
T11691 7603-7614 RB denotes Furthermore
T11692 7614-7615 , denotes ,
T11693 7616-7626 NN denotes production
T11694 7627-7629 IN denotes of
T11695 7630-7635 NNP denotes BMP-6
T11696 7636-7647 NNS denotes transcripts
T11697 7648-7650 IN denotes in
T11698 7651-7657 JJ denotes normal
T11699 7658-7667 VBN denotes activated
T11700 7668-7669 NNP denotes B
T11701 7670-7675 NNS denotes cells
T11702 7676-7679 VBD denotes was
T11703 7680-7688 VBN denotes detected
T11704 7689-7691 IN denotes in
T11705 7692-7695 DT denotes the
T11706 7696-7700 JJ denotes same
T11707 7701-7706 NN denotes study
T11708 7706-7707 . denotes .
T11709 7708-7710 IN denotes Of
T11710 7711-7715 NN denotes note
T11711 7715-7716 , denotes ,
T11712 7717-7719 DT denotes an
T11713 7720-7729 NN denotes autocrine
T11714 7730-7735 NN denotes BMP-6
T11715 7736-7740 NN denotes loop
T11716 7741-7744 VBZ denotes has
T11717 7745-7749 VBN denotes been
T11718 7750-7758 VBN denotes reported
T11719 7759-7761 IN denotes by
T11720 7762-7768 NNS denotes others
T11721 7769-7771 IN denotes in
T11722 7772-7784 NNS denotes chondrocytes
T11723 7785-7788 CC denotes and
T11724 7789-7791 IN denotes in
T11725 7792-7795 DT denotes the
T11726 7796-7803 NN denotes ovarium
T11727 7804-7805 NNP denotes [
T11728 7805-7813 CD denotes 46,19,18
T11729 7813-7814 NNP denotes ]
T11730 7814-7815 . denotes .
T11731 7816-7825 RB denotes Therefore
T11732 7825-7826 , denotes ,
T11733 7827-7829 PRP denotes we
T11734 7830-7836 VBD denotes wanted
T11735 7837-7839 TO denotes to
T11736 7840-7847 VB denotes explore
T11737 7848-7851 DT denotes the
T11738 7852-7863 NN denotes possibility
T11739 7864-7867 IN denotes for
T11740 7868-7870 DT denotes an
T11741 7871-7880 NN denotes autocrine
T11742 7881-7886 NN denotes BMP-6
T11743 7887-7891 NN denotes loop
T11744 7892-7894 IN denotes in
T11745 7895-7900 JJ denotes human
T11746 7901-7902 NNP denotes B
T11747 7903-7908 NNS denotes cells
T11748 7908-7909 . denotes .
T11749 7910-7912 PRP denotes We
T11750 7913-7921 VBD denotes analysed
T11751 7922-7925 DT denotes the
T11752 7926-7936 NN denotes expression
T11753 7937-7942 NNP denotes BMP-6
T11754 7943-7947 NNP denotes mRNA
T11755 7948-7950 IN denotes in
T11756 7951-7961 JJ denotes peripheral
T11757 7962-7967 NN denotes blood
T11758 7968-7969 NNP denotes B
T11759 7970-7975 NNS denotes cells
T11760 7976-7978 IN denotes by
T11761 7979-7988 JJ denotes real-time
T11762 7989-7992 NNP denotes PCR
T11763 7992-7993 , denotes ,
T11764 7994-7997 CC denotes and
T11765 7998-8004 NN denotes report
T11766 8005-8009 RB denotes here
T11767 8010-8013 DT denotes the
T11768 8014-8026 NN denotes upregulation
T11769 8027-8029 IN denotes of
T11770 8030-8040 JJ denotes endogenous
T11771 8041-8046 NN denotes BMP-6
T11772 8047-8058 NNS denotes transcripts
T11773 8059-8064 IN denotes after
T11774 8065-8076 NN denotes stimulation
T11775 8077-8081 IN denotes with
T11776 8082-8085 NNP denotes FCS
T11777 8085-8086 , denotes ,
T11778 8087-8092 JJ denotes human
T11779 8093-8101 NNP denotes AB-serum
T11780 8102-8105 CC denotes and
T11781 8105-8106 , denotes ,
T11782 8107-8111 RBS denotes most
T11783 8112-8123 RB denotes importantly
T11784 8123-8124 , denotes ,
T11785 8125-8133 JJ denotes anti-IgM
T11786 8133-8134 . denotes .
T11787 8135-8142 RB denotes However
T11788 8142-8143 , denotes ,
T11789 8144-8147 PRP$ denotes our
T11790 8148-8156 NNS denotes attempts
T11791 8157-8159 TO denotes to
T11792 8160-8165 VB denotes study
T11793 8166-8171 NNP denotes BMP-6
T11794 8172-8179 NN denotes protein
T11795 8180-8186 NNS denotes levels
T11796 8187-8191 VBD denotes were
T11797 8192-8204 JJ denotes unsuccessful
T11798 8205-8208 JJ denotes due
T11799 8209-8211 TO denotes to
T11800 8212-8220 NNS denotes problems
T11801 8221-8225 IN denotes with
T11802 8226-8236 JJ denotes unspecific
T11803 8237-8244 JJ denotes binding
T11804 8245-8247 IN denotes of
T11805 8248-8251 DT denotes the
T11806 8252-8262 JJ denotes anti-BMP-6
T11807 8263-8273 NNS denotes antibodies
T11808 8274-8280 VBN denotes tested
T11809 8280-8281 , denotes ,
T11810 8282-8285 CC denotes and
T11811 8286-8290 NN denotes lack
T11812 8291-8293 IN denotes of
T11813 8294-8302 JJ denotes specific
T11814 8303-8311 VBG denotes staining
T11815 8312-8314 IN denotes in
T11816 8315-8322 NN denotes control
T11817 8323-8328 NNS denotes cells
T11818 8329-8334 VBN denotes known
T11819 8335-8337 TO denotes to
T11820 8338-8345 VB denotes express
T11821 8346-8351 NNP denotes BMP-6
T11822 8352-8356 NNP denotes mRNA
T11823 8356-8357 . denotes .
T11824 8358-8360 IN denotes In
T11825 8361-8369 NN denotes contrast
T11826 8369-8370 , denotes ,
T11827 8371-8374 DT denotes the
T11828 8375-8386 JJ denotes recombinant
T11829 8387-8394 NN denotes protein
T11830 8395-8398 VBD denotes was
T11831 8399-8406 RB denotes readily
T11832 8407-8415 VBN denotes detected
T11833 8415-8416 . denotes .
T11834 8417-8419 IN denotes In
T11835 8420-8424 DT denotes that
T11836 8425-8432 NN denotes respect
T11837 8432-8433 , denotes ,
T11838 8434-8437 JJ denotes few
T11839 8438-8451 NNS denotes investigators
T11840 8452-8456 VBP denotes have
T11841 8457-8465 VBN denotes detected
T11842 8466-8471 NNP denotes BMP-6
T11843 8472-8479 NN denotes protein
T11844 8480-8482 IN denotes in
T11845 8483-8489 NNS denotes humans
T11846 8489-8490 , denotes ,
T11847 8491-8501 RB denotes especially
T11848 8502-8504 IN denotes in
T11849 8505-8519 JJ denotes non-pathogenic
T11850 8520-8526 NN denotes tissue
T11851 8526-8527 . denotes .
T11852 8528-8531 DT denotes The
T11853 8532-8543 NN denotes possibility
T11854 8544-8546 IN denotes of
T11855 8547-8552 NN denotes BMP-6
T11856 8553-8563 NN denotes production
T11857 8564-8566 IN denotes in
T11858 8567-8572 JJ denotes human
T11859 8573-8580 NNPS denotes B-cells
T11860 8581-8583 VBZ denotes is
T11861 8584-8586 IN denotes in
T11862 8587-8591 NN denotes line
T11863 8592-8596 IN denotes with
T11864 8597-8598 DT denotes a
T11865 8599-8605 JJ denotes recent
T11866 8606-8610 NN denotes work
T11867 8611-8615 WDT denotes that
T11868 8616-8624 VBD denotes reported
T11869 8625-8628 DT denotes the
T11870 8629-8639 NN denotes production
T11871 8640-8642 IN denotes of
T11872 8643-8648 NN denotes BMP-6
T11873 8649-8651 IN denotes in
T11874 8652-8657 NN denotes mouse
T11875 8658-8659 NNP denotes B
T11876 8660-8665 NNS denotes cells
T11877 8665-8666 , denotes ,
T11878 8667-8679 VBG denotes infiltrating
T11879 8680-8683 DT denotes the
T11880 8684-8688 NN denotes bone
T11881 8689-8695 NN denotes marrow
T11882 8696-8698 IN denotes of
T11883 8699-8703 NNS denotes mice
T11884 8704-8708 IN denotes with
T11885 8709-8721 JJ denotes inflammatory
T11886 8722-8731 NNS denotes arthritis
T11887 8732-8733 NNP denotes [
T11888 8733-8735 CD denotes 43
T11889 8735-8736 NNP denotes ]
T11890 8736-8737 . denotes .
T11891 8738-8740 IN denotes In
T11892 8741-8745 DT denotes this
T11893 8746-8751 NN denotes study
T11894 8751-8752 , denotes ,
T11895 8753-8754 DT denotes a
T11896 8755-8759 NN denotes role
T11897 8760-8763 IN denotes for
T11898 8764-8768 NNS denotes BMPs
T11899 8769-8771 IN denotes in
T11900 8772-8775 DT denotes the
T11901 8776-8789 JJ denotes inflammatoric
T11902 8790-8797 NN denotes process
T11903 8798-8800 IN denotes of
T11904 8801-8810 NN denotes arthritis
T11905 8811-8814 VBD denotes was
T11906 8815-8824 VBN denotes suggested
T11907 8824-8825 . denotes .
T11908 8826-8829 DT denotes The
T11909 8830-8842 NN denotes upregulation
T11910 8843-8845 IN denotes of
T11911 8846-8849 DT denotes the
T11912 8850-8867 NNS denotes BMP-6-transcripts
T11913 8868-8873 IN denotes after
T11914 8874-8890 NNP denotes IgM-crosslinking
T11915 8891-8893 VBZ denotes is
T11916 8894-8896 IN denotes of
T11917 8897-8913 JJ denotes pathophysiologic
T11918 8914-8922 NN denotes interest
T11919 8923-8924 NNP denotes [
T11920 8924-8926 CD denotes 12
T11921 8926-8927 NNP denotes ]
T11922 8927-8928 . denotes .
T11923 8929-8930 DT denotes A
T11924 8931-8935 NN denotes loss
T11925 8936-8938 IN denotes of
T11926 8939-8959 NN denotes TGF-β-responsiveness
T11927 8960-8963 VBZ denotes has
T11928 8964-8968 VBN denotes been
T11929 8969-8978 VBN denotes suggested
T11930 8979-8981 TO denotes to
T11931 8982-8984 VB denotes be
T11932 8985-8986 DT denotes a
T11933 8987-8995 JJ denotes critical
T11934 8996-9008 NN denotes contribution
T11935 9009-9011 TO denotes to
T11936 9012-9021 JJ denotes malignant
T11937 9022-9036 NN denotes transformation
T11938 9037-9038 NNP denotes [
T11939 9038-9043 CD denotes 47,48
T11940 9043-9044 NNP denotes ]
T11941 9045-9048 CC denotes and
T11942 9049-9056 JJ denotes similar
T11943 9057-9066 JJ denotes oncogenic
T11944 9067-9077 NNS denotes mechanisms
T11945 9078-9082 VBP denotes have
T11946 9083-9087 VBN denotes been
T11947 9088-9098 VBN denotes postulated
T11948 9099-9102 IN denotes for
T11949 9103-9107 NNS denotes BMPs
T11950 9107-9108 . denotes .
T11951 9109-9114 NNS denotes Lines
T11952 9115-9117 IN denotes of
T11953 9118-9126 NN denotes evidence
T11954 9127-9134 VBP denotes suggest
T11955 9135-9136 NNP denotes [
T11956 9136-9138 CD denotes 49
T11957 9138-9139 NN denotes ]
T11958 9140-9144 WDT denotes that
T11959 9145-9147 IN denotes at
T11960 9148-9153 JJ denotes early
T11961 9154-9160 NNS denotes stages
T11962 9161-9163 IN denotes of
T11963 9164-9178 NN denotes carcinogenesis
T11964 9178-9179 , denotes ,
T11965 9180-9185 NNP denotes BMP-6
T11966 9186-9188 VBZ denotes is
T11967 9189-9192 RB denotes not
T11968 9193-9194 DT denotes a
T11969 9195-9201 NN denotes tumour
T11970 9202-9210 NN denotes promoter
T11971 9210-9211 , denotes ,
T11972 9212-9215 CC denotes but
T11973 9216-9226 VBZ denotes suppresses
T11974 9227-9233 JJ denotes benign
T11975 9234-9237 CC denotes and
T11976 9238-9247 JJ denotes malignant
T11977 9248-9254 NN denotes tumour
T11978 9255-9264 NN denotes outgrowth
T11979 9264-9265 . denotes .
T11980 9266-9271 DT denotes These
T11981 9272-9280 NNS denotes findings
T11982 9281-9284 VBP denotes are
T11983 9285-9287 IN denotes in
T11984 9288-9292 JJ denotes good
T11985 9293-9302 NN denotes agreement
T11986 9303-9307 IN denotes with
T11987 9308-9316 JJ denotes previous
T11988 9317-9325 NNS denotes findings
T11989 9326-9329 IN denotes for
T11990 9330-9335 JJ denotes other
T11991 9336-9341 NNP denotes TGF-β
T11992 9342-9348 NN denotes family
T11993 9349-9356 NNS denotes members
T11994 9356-9357 , denotes ,
T11995 9358-9367 VBG denotes including
T11996 9368-9374 NNP denotes TGF-β1
T11997 9375-9378 CC denotes and
T11998 9379-9384 NNP denotes BMP-4
T11999 9385-9386 NNP denotes [
T12000 9386-9388 CD denotes 50
T12001 9388-9389 NNP denotes ]
T12002 9389-9390 , denotes ,
T12003 9391-9401 VBG denotes indicating
T12004 9402-9406 IN denotes that
T12005 9407-9415 JJ denotes cellular
T12006 9416-9423 NN denotes context
T12007 9424-9426 IN denotes of
T12008 9427-9430 DT denotes the
T12009 9431-9434 NN denotes BMP
T12010 9435-9441 NN denotes target
T12011 9442-9446 NN denotes cell
T12012 9447-9452 MD denotes might
T12013 9453-9459 VB denotes define
T12014 9460-9463 DT denotes the
T12015 9464-9471 JJ denotes various
T12016 9472-9480 JJ denotes observed
T12017 9481-9488 NNS denotes effects
T12018 9488-9489 . denotes .
T12019 9490-9492 IN denotes In
T12020 9493-9501 NN denotes contrast
T12021 9502-9504 TO denotes to
T12022 9505-9508 DT denotes the
T12023 9509-9521 NN denotes upregulation
T12024 9522-9524 IN denotes of
T12025 9525-9530 NNP denotes BMP-6
T12026 9531-9541 NN denotes transcript
T12027 9542-9544 IN denotes in
T12028 9545-9546 NNP denotes B
T12029 9547-9552 NNS denotes cells
T12030 9552-9553 , denotes ,
T12031 9554-9556 PRP denotes we
T12032 9557-9561 VBD denotes were
T12033 9562-9565 RB denotes not
T12034 9566-9570 JJ denotes able
T12035 9571-9573 TO denotes to
T12036 9574-9580 VB denotes detect
T12037 9581-9586 NNP denotes BMP-6
T12038 9587-9598 NNS denotes transcripts
T12039 9599-9601 IN denotes in
T12040 9602-9607 JJ denotes human
T12041 9608-9618 JJ denotes peripheral
T12042 9619-9624 NN denotes blood
T12043 9625-9628 NNP denotes CD4
T12044 9628-9629 CD denotes +
T12045 9630-9632 CC denotes or
T12046 9633-9636 CD denotes CD8
T12047 9636-9637 CD denotes +
T12048 9638-9639 NNP denotes T
T12049 9640-9645 NNS denotes cells
T12050 9646-9647 -LRB- denotes (
T12051 9647-9654 VBG denotes resting
T12052 9655-9657 CC denotes or
T12053 9658-9668 VBN denotes stimulated
T12054 9669-9673 IN denotes with
T12055 9674-9682 JJ denotes anti-CD3
T12056 9683-9686 CC denotes and
T12057 9687-9696 JJ denotes anti-CD28
T12058 9696-9697 : denotes ;
T12059 9698-9702 NNS denotes data
T12060 9703-9706 RB denotes not
T12061 9707-9712 VBN denotes shown
T12062 9712-9713 -RRB- denotes )
T12063 9713-9714 , denotes ,
T12064 9715-9725 JJ denotes consistent
T12065 9726-9730 IN denotes with
T12066 9731-9734 DT denotes the
T12067 9735-9743 NNS denotes findings
T12068 9744-9746 IN denotes in
T12069 9747-9748 NNP denotes T
T12070 9749-9753 NN denotes cell
T12071 9754-9759 NNS denotes lines
T12072 9760-9761 NNP denotes [
T12073 9761-9763 CD denotes 20
T12074 9763-9764 NNP denotes ]
T12075 9765-9768 CC denotes and
T12076 9769-9770 NNP denotes T
T12077 9771-9776 NNS denotes cells
T12078 9777-9779 IN denotes in
T12079 9780-9784 NNS denotes mice
T12080 9785-9786 NNP denotes [
T12081 9786-9788 CD denotes 43
T12082 9788-9789 NNP denotes ]
T12083 9789-9790 . denotes .
T12084 9791-9796 JJ denotes Other
T12085 9797-9806 JJ denotes potential
T12086 9807-9812 NN denotes BMP-6
T12087 9813-9820 NNS denotes sources
T12088 9821-9824 IN denotes for
T12089 9825-9831 JJ denotes mature
T12090 9832-9833 NNP denotes B
T12091 9834-9839 NNS denotes cells
T12092 9840-9842 IN denotes in
T12093 9843-9847 NN denotes vivo
T12094 9848-9853 MD denotes might
T12095 9854-9856 VB denotes be
T12096 9857-9862 JJ denotes other
T12097 9863-9868 NNS denotes cells
T12098 9869-9871 IN denotes of
T12099 9872-9875 DT denotes the
T12100 9876-9882 JJ denotes immune
T12101 9883-9889 NN denotes system
T12102 9890-9892 CC denotes or
T12103 9893-9899 NN denotes tissue
T12104 9900-9904 IN denotes with
T12105 9905-9912 NN denotes contact
T12106 9913-9915 TO denotes to
T12107 9916-9919 DT denotes the
T12108 9920-9933 JJ denotes hematopoietic
T12109 9934-9940 NN denotes system
T12110 9940-9941 . denotes .
T12111 9942-9945 CD denotes One
T12112 9946-9950 RB denotes well
T12113 9951-9961 VBN denotes recognized
T12114 9962-9968 NN denotes source
T12115 9969-9972 IN denotes for
T12116 9973-9978 NN denotes BMP-6
T12117 9979-9989 NN denotes production
T12118 9990-9992 VBZ denotes is
T12119 9993-9996 DT denotes the
T12120 9997-10002 JJ denotes human
T12121 10003-10007 NN denotes bone
T12122 10008-10011 CC denotes and
T12123 10012-10016 NN denotes bone
T12124 10017-10023 NN denotes marrow
T12125 10024-10030 NN denotes stroma
T12126 10031-10032 NNP denotes [
T12127 10032-10036 CD denotes 51,8
T12128 10036-10037 NNP denotes ]
T12129 10037-10038 . denotes .
T12130 10039-10050 RB denotes Furthermore
T12131 10050-10051 , denotes ,
T12132 10052-10054 PRP denotes it
T12133 10055-10057 VBZ denotes is
T12134 10058-10068 JJ denotes noteworthy
T12135 10069-10073 IN denotes that
T12136 10074-10079 JJ denotes human
T12137 10080-10089 JJ denotes umbilical
T12138 10090-10094 NN denotes vein
T12139 10095-10106 JJ denotes endothelial
T12140 10107-10112 NNS denotes cells
T12141 10113-10114 -LRB- denotes (
T12142 10114-10119 NNP denotes HUVEC
T12143 10119-10120 -RRB- denotes )
T12144 10121-10127 RB denotes highly
T12145 10128-10135 JJ denotes express
T12146 10136-10141 NNP denotes BMP-6
T12147 10142-10146 NNP denotes mRNA
T12148 10147-10148 NNP denotes [
T12149 10148-10150 CD denotes 52
T12150 10150-10151 NNP denotes ]
T12151 10151-10152 , denotes ,
T12152 10153-10156 CC denotes and
T12153 10157-10165 JJ denotes vascular
T12154 10166-10177 NN denotes endothelium
T12155 10178-10181 VBZ denotes has
T12156 10182-10186 VBN denotes been
T12157 10187-10195 VBN denotes reported
T12158 10196-10198 TO denotes to
T12159 10199-10206 VB denotes produce
T12160 10207-10212 NNP denotes BMP-6
T12161 10213-10214 NNP denotes [
T12162 10214-10216 CD denotes 53
T12163 10216-10217 NNP denotes ]
T12164 10217-10218 . denotes .
T12165 10219-10224 DT denotes These
T12166 10225-10232 NNS denotes studies
T12167 10233-10238 MD denotes might
T12168 10239-10244 VB denotes imply
T12169 10245-10246 DT denotes a
T12170 10247-10251 NN denotes role
T12171 10252-10255 IN denotes for
T12172 10256-10261 NNP denotes BMP-6
T12173 10262-10264 IN denotes in
T12174 10265-10281 JJ denotes transendothelial
T12175 10282-10291 NN denotes migration
T12176 10292-10294 IN denotes of
T12177 10295-10296 NNP denotes B
T12178 10297-10302 NNS denotes cells
T12179 10302-10303 . denotes .
T12180 10304-10309 CD denotes BMP-6
T12181 10310-10314 NNP denotes mRNA
T12182 10315-10318 VBZ denotes has
T12183 10319-10323 VBN denotes been
T12184 10324-10336 VBN denotes demonstrated
T12185 10337-10339 IN denotes in
T12186 10340-10346 NN denotes murine
T12187 10347-10357 NN denotes macrophage
T12188 10358-10362 NN denotes cell
T12189 10363-10368 NNS denotes lines
T12190 10368-10369 , denotes ,
T12191 10370-10373 CC denotes but
T12192 10374-10377 RB denotes not
T12193 10378-10380 IN denotes in
T12194 10381-10387 NNS denotes humans
T12195 10388-10389 NNP denotes [
T12196 10389-10391 CD denotes 54
T12197 10391-10392 NNP denotes ]
T12198 10392-10393 . denotes .
T12199 10394-10396 IN denotes In
T12200 10397-10407 NN denotes accordance
T12201 10408-10412 IN denotes with
T12202 10413-10418 DT denotes these
T12203 10419-10427 NNS denotes findings
T12204 10427-10428 , denotes ,
T12205 10429-10434 JJ denotes other
T12206 10435-10440 JJ denotes human
T12207 10441-10445 NN denotes cell
T12208 10446-10451 NNS denotes lines
T12209 10452-10454 IN denotes of
T12210 10455-10465 NN denotes neutrophil
T12211 10466-10469 CC denotes and
T12212 10470-10479 JJ denotes monocytic
T12213 10480-10486 NN denotes origin
T12214 10487-10491 VBP denotes have
T12215 10492-10496 VBN denotes been
T12216 10497-10506 VBN denotes described
T12217 10507-10509 TO denotes to
T12218 10510-10512 VB denotes be
T12219 10513-10521 JJ denotes negative
T12220 10522-10525 IN denotes for
T12221 10526-10529 DT denotes the
T12222 10530-10535 NNP denotes BMP-6
T12223 10536-10546 NN denotes transcript
T12224 10547-10548 NNP denotes [
T12225 10548-10550 CD denotes 20
T12226 10550-10551 NNP denotes ]
T12227 10551-10552 . denotes .
T12228 10553-10555 TO denotes To
T12229 10556-10559 PRP$ denotes our
T12230 10560-10569 NN denotes knowledge
T12231 10569-10570 , denotes ,
T12232 10571-10576 EX denotes there
T12233 10577-10579 VBZ denotes is
T12234 10580-10589 RB denotes currently
T12235 10590-10592 DT denotes no
T12236 10593-10599 NN denotes report
T12237 10600-10605 IN denotes about
T12238 10606-10611 NN denotes BMP-6
T12239 10612-10622 NN denotes production
T12240 10623-10625 IN denotes of
T12241 10626-10631 JJ denotes human
T12242 10632-10641 JJ denotes dendritic
T12243 10642-10647 NNS denotes cells
T12244 10647-10648 . denotes .
R7899 T10336 T10338 amod hematopoietic,cells
R7900 T10324 T10325 amod Recent,studies
R7901 T10325 T10327 nsubj studies,demonstrated
R7902 T10326 T10327 aux have,demonstrated
R7903 T10327 T10366 ccomp demonstrated,reported
R7904 T10328 T10330 det an,role
R7905 T10329 T10330 amod important,role
R7906 T10330 T10327 dobj role,demonstrated
R7907 T10331 T10330 prep for,role
R7908 T10332 T10334 compound BMP,members
R7909 T10333 T10334 compound superfamily,members
R7910 T10334 T10331 pobj members,for
R7911 T10335 T10330 prep in,role
R7912 T10337 T10338 compound stem,cells
R7913 T10338 T10335 pobj cells,in
R7914 T10383 T10384 compound B,cells
R7915 T10339 T10330 punct ",",role
R7916 T10384 T10378 pobj cells,in
R7917 T10385 T10371 punct .,demonstrated
R7918 T10386 T10389 advmod Additionally,induced
R7919 T10340 T10341 amod early,thymocytes
R7920 T10387 T10389 punct ",",induced
R7921 T10388 T10389 nsubj BMP-6,induced
R7922 T10389 T10389 ROOT induced,induced
R7923 T10341 T10344 nmod thymocytes,]
R7924 T10390 T10391 compound cell,death
R7925 T10391 T10389 dobj death,induced
R7926 T10392 T10389 prep in,induced
R7927 T10342 T10344 nmod [,]
R7928 T10393 T10396 compound CD27,B
R7929 T10394 T10396 compound +,B
R7930 T10395 T10396 compound memory,B
R7931 T10343 T10344 nummod "6,7",]
R7932 T10396 T10397 compound B,cells
R7933 T10397 T10392 pobj cells,in
R7934 T10398 T10400 advmod as,as
R7935 T10344 T10347 nmod ],malignancies
R7936 T10399 T10400 advmod well,as
R7937 T10400 T10392 cc as,in
R7938 T10401 T10392 conj in,in
R7939 T10345 T10344 cc and,]
R7940 T10402 T10406 det a,line
R7941 T10403 T10406 compound Burkitt,line
R7942 T10404 T10405 compound lymphoma,cell
R7943 T10346 T10344 conj B-cell,]
R7944 T10405 T10406 compound cell,line
R7945 T10406 T10401 pobj line,in
R7946 T10347 T10366 nsubj malignancies,reported
R7947 T10407 T10406 punct (,line
R7948 T10408 T10406 appos Ramos,line
R7949 T10409 T10406 punct ),line
R7950 T10348 T10350 compound [,]
R7951 T10410 T10389 punct .,induced
R7952 T10411 T10414 advmod Importantly,induced
R7953 T10349 T10350 compound "8,11,12",]
R7954 T10412 T10414 punct ",",induced
R7955 T10413 T10414 nsubj BMP-6,induced
R7956 T10414 T10414 ROOT induced,induced
R7957 T10415 T10419 det a,increase
R7958 T10416 T10419 amod rapid,increase
R7959 T10417 T10416 cc and,rapid
R7960 T10418 T10416 conj marked,rapid
R7961 T10350 T10347 dobj ],malignancies
R7962 T10419 T10414 dobj increase,induced
R7963 T10420 T10419 prep in,increase
R7964 T10421 T10424 quantmod Smad-1,phosphorylation
R7965 T10351 T10347 punct ",",malignancies
R7966 T10422 T10423 compound /,5/8
R7967 T10423 T10424 nummod 5/8,phosphorylation
R7968 T10352 T10347 cc but,malignancies
R7969 T10353 T10354 det a,role
R7970 T10424 T10420 pobj phosphorylation,in
R7971 T10354 T10347 conj role,malignancies
R7972 T10425 T10414 punct .,induced
R7973 T10426 T10430 advmod Furthermore,induced
R7974 T10427 T10430 punct ",",induced
R7975 T10355 T10354 prep for,role
R7976 T10428 T10429 det the,BMP-6
R7977 T10429 T10430 nsubj BMP-6,induced
R7978 T10356 T10355 pobj BMPs,for
R7979 T10430 T10430 ROOT induced,induced
R7980 T10431 T10432 compound Smad,phosphorylation
R7981 T10432 T10434 nsubjpass phosphorylation,followed
R7982 T10357 T10356 prep in,BMPs
R7983 T10433 T10434 auxpass was,followed
R7984 T10434 T10430 advcl followed,induced
R7985 T10435 T10434 agent by,followed
R7986 T10358 T10361 amod normal,cells
R7987 T10436 T10438 det a,upregulation
R7988 T10437 T10438 amod selective,upregulation
R7989 T10438 T10435 pobj upregulation,by
R7990 T10359 T10361 amod human,cells
R7991 T10439 T10438 prep of,upregulation
R7992 T10440 T10441 compound Id1,mRNA
R7993 T10441 T10439 pobj mRNA,of
R7994 T10442 T10441 cc and,mRNA
R7995 T10360 T10361 compound B,cells
R7996 T10361 T10357 pobj cells,in
R7997 T10443 T10445 amod subsequent,protein
R7998 T10444 T10445 amod Id1,protein
R7999 T10362 T10366 aux has,reported
R8000 T10445 T10438 conj protein,upregulation
R8001 T10446 T10434 punct .,followed
R8002 T10363 T10366 advmod previously,reported
R8003 T10447 T10463 prep In,was
R8004 T10448 T10450 det the,study
R8005 T10449 T10450 amod present,study
R8006 T10364 T10366 neg not,reported
R8007 T10450 T10447 pobj study,In
R8008 T10451 T10463 punct ",",was
R8009 T10452 T10455 det the,effect
R8010 T10453 T10455 amod demonstrated,effect
R8011 T10454 T10455 amod antiproliferative,effect
R8012 T10455 T10463 nsubj effect,was
R8013 T10365 T10366 auxpass been,reported
R8014 T10456 T10455 prep of,effect
R8015 T10457 T10456 pobj BMP-6,of
R8016 T10458 T10457 prep in,BMP-6
R8017 T10366 T10366 ROOT reported,reported
R8018 T10459 T10462 amod anti-IgM,cells
R8019 T10460 T10462 amod treated,cells
R8020 T10367 T10366 punct .,reported
R8021 T10461 T10462 compound B,cells
R8022 T10462 T10458 pobj cells,in
R8023 T10463 T10463 ROOT was,was
R8024 T10464 T10463 acomp significant,was
R8025 T10368 T10370 det The,study
R8026 T10465 T10464 cc and,significant
R8027 T10466 T10464 conj dose-dependent,significant
R8028 T10467 T10463 punct .,was
R8029 T10468 T10478 advmod Importantly,neutralized
R8030 T10369 T10370 amod present,study
R8031 T10469 T10478 punct ",",neutralized
R8032 T10470 T10472 det the,effect
R8033 T10471 T10472 amod anti-proliferative,effect
R8034 T10370 T10371 nsubj study,demonstrated
R8035 T10472 T10478 nsubjpass effect,neutralized
R8036 T10473 T10472 prep of,effect
R8037 T10371 T10371 ROOT demonstrated,demonstrated
R8038 T10474 T10473 pobj BMP-6,of
R8039 T10475 T10478 aux could,neutralized
R8040 T10476 T10478 auxpass be,neutralized
R8041 T10372 T10375 det a,effect
R8042 T10477 T10478 advmod completely,neutralized
R8043 T10478 T10478 ROOT neutralized,neutralized
R8044 T10373 T10375 amod significant,effect
R8045 T10374 T10375 amod antiproliferative,effect
R8046 T10375 T10371 dobj effect,demonstrated
R8047 T10479 T10478 agent by,neutralized
R8048 T10376 T10375 prep of,effect
R8049 T10480 T10481 det the,use
R8050 T10481 T10479 pobj use,by
R8051 T10377 T10376 pobj BMP-6,of
R8052 T10482 T10481 prep of,use
R8053 T10483 T10485 det a,inhibitor
R8054 T10484 T10485 amod natural,inhibitor
R8055 T10378 T10377 prep in,BMP-6
R8056 T10485 T10482 pobj inhibitor,of
R8057 T10486 T10481 punct ",",use
R8058 T10379 T10380 amod peripheral,blood
R8059 T10487 T10481 appos Noggin,use
R8060 T10488 T10478 punct .,neutralized
R8061 T10489 T10490 nsubj This,is
R8062 T10490 T10490 ROOT is,is
R8063 T10491 T10490 prep in,is
R8064 T10380 T10384 compound blood,cells
R8065 T10492 T10491 pobj line,in
R8066 T10493 T10492 prep with,line
R8067 T10494 T10493 pobj others,with
R8068 T10495 T10490 punct ",",is
R8069 T10381 T10383 compound CD19,B
R8070 T10496 T10490 advcl showing,is
R8071 T10497 T10500 mark that,function
R8072 T10382 T10383 compound +,B
R8073 T10498 T10500 nsubj Noggin,function
R8074 T10499 T10500 aux can,function
R8075 T10500 T10496 ccomp function,showing
R8076 T10541 T10547 punct ",",demonstrated
R8077 T10501 T10500 prep as,function
R8078 T10502 T10504 det a,antagonist
R8079 T10542 T10543 amod bifunctional,effects
R8080 T10543 T10547 nsubj effects,demonstrated
R8081 T10503 T10504 compound BMP-6,antagonist
R8082 T10504 T10501 pobj antagonist,as
R8083 T10505 T10507 compound [,]
R8084 T10544 T10547 aux have,demonstrated
R8085 T10506 T10507 compound "21,22",]
R8086 T10507 T10504 appos ],antagonist
R8087 T10545 T10547 advmod also,demonstrated
R8088 T10508 T10490 punct .,is
R8089 T10509 T10522 prep In,neutralized
R8090 T10546 T10547 auxpass been,demonstrated
R8091 T10510 T10509 pobj addition,In
R8092 T10511 T10522 punct ",",neutralized
R8093 T10512 T10513 det the,combination
R8094 T10547 T10547 ROOT demonstrated,demonstrated
R8095 T10513 T10522 nsubj combination,neutralized
R8096 T10514 T10513 prep of,combination
R8097 T10548 T10547 prep for,demonstrated
R8098 T10515 T10520 amod soluble,proteins
R8099 T10516 T10519 nmod BMP-RIB-Fc,fusion
R8100 T10517 T10516 cc and,BMP-RIB-Fc
R8101 T10549 T10548 pobj BMPs,for
R8102 T10518 T10516 conj BMP-RII-Fc,BMP-RIB-Fc
R8103 T10519 T10520 compound fusion,proteins
R8104 T10520 T10514 pobj proteins,of
R8105 T10550 T10547 punct .,demonstrated
R8106 T10521 T10522 advmod also,neutralized
R8107 T10522 T10522 ROOT neutralized,neutralized
R8108 T10523 T10525 det the,effect
R8109 T10551 T10558 mark Whereas,shown
R8110 T10524 T10525 amod anti-proliferative,effect
R8111 T10525 T10522 dobj effect,neutralized
R8112 T10526 T10525 prep of,effect
R8113 T10527 T10526 pobj BMP-6,of
R8114 T10528 T10522 prep in,neutralized
R8115 T10552 T10558 nsubjpass several,shown
R8116 T10529 T10531 amod human,cells
R8117 T10530 T10531 compound B,cells
R8118 T10553 T10552 prep of,several
R8119 T10554 T10555 det the,BMPs
R8120 T10531 T10528 pobj cells,in
R8121 T10555 T10553 pobj BMPs,of
R8122 T10532 T10522 punct .,neutralized
R8123 T10533 T10547 advmod Interestingly,demonstrated
R8124 T10556 T10558 aux have,shown
R8125 T10534 T10547 punct ",",demonstrated
R8126 T10535 T10547 prep as,demonstrated
R8127 T10536 T10535 prep for,as
R8128 T10537 T10540 amod other,members
R8129 T10557 T10558 auxpass been,shown
R8130 T10538 T10540 compound TGF,members
R8131 T10539 T10540 compound family,members
R8132 T10540 T10536 pobj members,for
R8133 T10558 T10591 advcl shown,reported
R8134 T10559 T10560 aux to,promote
R8135 T10560 T10558 xcomp promote,shown
R8136 T10575 T10578 nmod ],cells
R8137 T10576 T10575 cc and,]
R8138 T10561 T10560 dobj proliferation,promote
R8139 T10577 T10575 conj granulosa,]
R8140 T10578 T10591 nsubjpass cells,reported
R8141 T10562 T10560 prep in,promote
R8142 T10579 T10581 nmod [,]
R8143 T10580 T10581 nummod 25,]
R8144 T10563 T10565 amod various,types
R8145 T10581 T10578 dobj ],cells
R8146 T10564 T10565 compound cell,types
R8147 T10565 T10562 pobj types,in
R8148 T10582 T10581 punct ",",]
R8149 T10583 T10584 amod antiproliferative,effects
R8150 T10566 T10565 prep including,types
R8151 T10584 T10581 conj effects,]
R8152 T10585 T10584 cc and,effects
R8153 T10567 T10568 nmod condrocytes,[
R8154 T10586 T10584 conj induction,effects
R8155 T10587 T10586 prep of,induction
R8156 T10588 T10587 pobj apoptosis,of
R8157 T10568 T10570 nmod [,]
R8158 T10589 T10591 aux has,reported
R8159 T10590 T10591 auxpass been,reported
R8160 T10591 T10591 ROOT reported,reported
R8161 T10592 T10591 prep for,reported
R8162 T10593 T10597 nmod B,cells
R8163 T10569 T10570 nummod 23,]
R8164 T10594 T10593 cc and,B
R8165 T10595 T10593 conj T,B
R8166 T10596 T10597 compound lineage,cells
R8167 T10570 T10566 pobj ],including
R8168 T10597 T10592 pobj cells,for
R8169 T10598 T10591 punct .,reported
R8170 T10571 T10570 punct ",",]
R8171 T10599 T10600 amod Similar,effects
R8172 T10600 T10615 nsubjpass effects,demonstrated
R8173 T10601 T10602 mark as,demonstrated
R8174 T10572 T10578 nsubj liver,cells
R8175 T10602 T10600 advcl demonstrated,effects
R8176 T10573 T10575 nmod [,]
R8177 T10603 T10602 prep for,demonstrated
R8178 T10574 T10575 nummod 24,]
R8179 T10604 T10603 pobj BMP-6,for
R8180 T10605 T10604 prep on,BMP-6
R8181 T10639 T10640 auxpass been,reported
R8182 T10606 T10608 amod human,cells
R8183 T10607 T10608 compound B,cells
R8184 T10608 T10605 pobj cells,on
R8185 T10609 T10602 prep in,demonstrated
R8186 T10610 T10612 det the,study
R8187 T10611 T10612 amod present,study
R8188 T10640 T10640 ROOT reported,reported
R8189 T10612 T10609 pobj study,in
R8190 T10613 T10615 punct ",",demonstrated
R8191 T10614 T10615 auxpass were,demonstrated
R8192 T10641 T10642 aux to,induce
R8193 T10615 T10615 ROOT demonstrated,demonstrated
R8194 T10616 T10615 prep for,demonstrated
R8195 T10617 T10616 pobj BMP-2,for
R8196 T10642 T10640 xcomp induce,reported
R8197 T10618 T10617 punct ",",BMP-2
R8198 T10619 T10617 appos 4,BMP-2
R8199 T10643 T10642 dobj apoptosis,induce
R8200 T10620 T10617 punct ",",BMP-2
R8201 T10621 T10617 conj 6,BMP-2
R8202 T10622 T10621 cc and,6
R8203 T10644 T10643 punct ",",apoptosis
R8204 T10623 T10621 conj -7,6
R8205 T10624 T10623 prep in,-7
R8206 T10625 T10627 amod human,cells
R8207 T10645 T10643 prep including,apoptosis
R8208 T10626 T10627 compound myeloma,cells
R8209 T10627 T10624 pobj cells,in
R8210 T10646 T10645 prep in,including
R8211 T10628 T10630 compound [,]
R8212 T10629 T10630 compound 9-11,]
R8213 T10630 T10617 appos ],BMP-2
R8214 T10631 T10615 punct .,demonstrated
R8215 T10632 T10633 amod Other,members
R8216 T10633 T10640 nsubj members,reported
R8217 T10647 T10649 compound mouse,lineage
R8218 T10634 T10633 prep of,members
R8219 T10635 T10636 det the,BMP-family
R8220 T10636 T10634 pobj BMP-family,of
R8221 T10648 T10649 compound B,lineage
R8222 T10637 T10640 aux have,reported
R8223 T10638 T10640 advmod also,reported
R8224 T10649 T10650 compound lineage,cells
R8225 T10650 T10646 pobj cells,in
R8226 T10651 T10653 nmod [,]
R8227 T10652 T10653 nummod 26,]
R8228 T10653 T10645 pobj ],including
R8229 T10671 T10683 mark that,is
R8230 T10672 T10673 det the,role
R8231 T10654 T10640 punct .,reported
R8232 T10673 T10683 nsubj role,is
R8233 T10674 T10673 prep of,role
R8234 T10655 T10658 advmod Additionally,inhibits
R8235 T10675 T10674 pobj BMPs,of
R8236 T10676 T10675 prep in,BMPs
R8237 T10677 T10678 det the,regulation
R8238 T10656 T10658 punct ",",inhibits
R8239 T10678 T10676 pobj regulation,in
R8240 T10679 T10678 prep of,regulation
R8241 T10680 T10679 pobj proliferation,of
R8242 T10657 T10658 nsubj BMP-4,inhibits
R8243 T10658 T10658 ROOT inhibits,inhibits
R8244 T10659 T10661 nmod thymocyte,[
R8245 T10681 T10680 cc and,proliferation
R8246 T10682 T10680 conj apoptosis,proliferation
R8247 T10660 T10661 compound proliferation,[
R8248 T10683 T10670 ccomp is,suggest
R8249 T10684 T10685 advmod highly,cell
R8250 T10685 T10686 compound cell,type
R8251 T10661 T10658 dobj [,inhibits
R8252 T10686 T10687 npadvmod type,dependent
R8253 T10687 T10683 acomp dependent,is
R8254 T10688 T10670 punct .,suggest
R8255 T10689 T10690 aux To,examine
R8256 T10690 T10702 advcl examine,analysed
R8257 T10662 T10663 nummod 6,]
R8258 T10691 T10693 advmod how,exerts
R8259 T10692 T10693 nsubj BMP-6,exerts
R8260 T10693 T10690 ccomp exerts,examine
R8261 T10694 T10696 poss its,effects
R8262 T10695 T10696 amod functional,effects
R8263 T10663 T10661 appos ],[
R8264 T10696 T10693 dobj effects,exerts
R8265 T10697 T10696 prep in,effects
R8266 T10698 T10699 compound B,cells
R8267 T10664 T10658 punct .,inhibits
R8268 T10699 T10697 pobj cells,in
R8269 T10700 T10702 punct ",",analysed
R8270 T10701 T10702 nsubj we,analysed
R8271 T10665 T10670 advcl Taken,suggest
R8272 T10702 T10702 ROOT analysed,analysed
R8273 T10703 T10705 compound BMP,expression
R8274 T10666 T10665 advmod together,Taken
R8275 T10704 T10705 compound receptor,expression
R8276 T10705 T10702 dobj expression,analysed
R8277 T10706 T10705 prep by,expression
R8278 T10667 T10670 punct ",",suggest
R8279 T10707 T10709 amod western,analysis
R8280 T10708 T10709 compound blot,analysis
R8281 T10668 T10669 det these,data
R8282 T10709 T10706 pobj analysis,by
R8283 T10710 T10702 punct .,analysed
R8284 T10711 T10714 amod Human,cells
R8285 T10669 T10670 nsubj data,suggest
R8286 T10712 T10714 amod peripheral,cells
R8287 T10713 T10714 compound B,cells
R8288 T10714 T10716 nsubjpass cells,found
R8289 T10670 T10670 ROOT suggest,suggest
R8290 T10715 T10716 auxpass were,found
R8291 T10716 T10716 ROOT found,found
R8292 T10717 T10718 aux to,express
R8293 T10737 T10723 relcl signal,receptors
R8294 T10718 T10716 advcl express,found
R8295 T10719 T10721 det the,type
R8296 T10720 T10721 compound BMP,type
R8297 T10738 T10737 prep after,signal
R8298 T10721 T10718 dobj type,express
R8299 T10722 T10723 nsubj I,receptors
R8300 T10723 T10721 relcl receptors,type
R8301 T10739 T10738 pobj binding,after
R8302 T10724 T10723 dobj Act-RIA,receptors
R8303 T10725 T10724 cc and,Act-RIA
R8304 T10740 T10739 prep of,binding
R8305 T10726 T10724 conj BMP-RIB,Act-RIA
R8306 T10727 T10726 punct ",",BMP-RIB
R8307 T10728 T10726 cc and,BMP-RIB
R8308 T10729 T10730 det the,type
R8309 T10741 T10742 amod several,BMPs
R8310 T10730 T10726 conj type,BMP-RIB
R8311 T10731 T10732 compound II-receptors,BMP-RII
R8312 T10732 T10724 conj BMP-RII,Act-RIA
R8313 T10733 T10732 cc and,BMP-RII
R8314 T10734 T10732 conj Act-RIIb,BMP-RII
R8315 T10735 T10724 punct ",",Act-RIA
R8316 T10736 T10737 nsubj which,signal
R8317 T10742 T10740 pobj BMPs,of
R8318 T10743 T10742 punct ",",BMPs
R8319 T10744 T10742 prep including,BMPs
R8320 T10745 T10746 compound BMP-6,[
R8321 T10746 T10744 pobj [,including
R8322 T10747 T10748 nummod "16,13",]
R8323 T10748 T10746 appos ],[
R8324 T10834 T10838 nsubjpass BMP-2,shown
R8325 T10835 T10838 aux has,shown
R8326 T10749 T10716 punct .,found
R8327 T10836 T10838 advmod also,shown
R8328 T10837 T10838 auxpass been,shown
R8329 T10750 T10752 aux To,explore
R8330 T10838 T10838 ROOT shown,shown
R8331 T10839 T10840 aux to,induce
R8332 T10840 T10838 xcomp induce,shown
R8333 T10751 T10752 advmod further,explore
R8334 T10841 T10840 dobj phosphorylation,induce
R8335 T10842 T10841 prep of,phosphorylation
R8336 T10752 T10761 advcl explore,is
R8337 T10843 T10846 nummod p38,]
R8338 T10844 T10846 nmod [,]
R8339 T10845 T10846 nummod 29,]
R8340 T10846 T10842 pobj ],of
R8341 T10753 T10754 nsubj BMP-6,induced
R8342 T10847 T10838 punct .,shown
R8343 T10848 T10857 advmod Thus,represent
R8344 T10754 T10761 advcl induced,is
R8345 T10849 T10857 punct ",",represent
R8346 T10850 T10857 nsubj phosphorylation,represent
R8347 T10851 T10850 prep of,phosphorylation
R8348 T10755 T10754 prt signalling,induced
R8349 T10852 T10851 pobj p38,of
R8350 T10853 T10850 punct ",",phosphorylation
R8351 T10854 T10850 conj STAT3,phosphorylation
R8352 T10756 T10755 punct ",",signalling
R8353 T10855 T10854 cc and,STAT3
R8354 T10856 T10854 conj Smad1/5/8,STAT3
R8355 T10757 T10761 nsubj activation,is
R8356 T10857 T10857 ROOT represent,represent
R8357 T10858 T10860 amod important,pathways
R8358 T10859 T10860 amod BMP-signalling,pathways
R8359 T10758 T10757 prep of,activation
R8360 T10860 T10857 dobj pathways,represent
R8361 T10861 T10862 nsubj that,mediated
R8362 T10862 T10860 relcl mediated,pathways
R8363 T10863 T10864 det the,effects
R8364 T10864 T10862 dobj effects,mediated
R8365 T10865 T10864 prep of,effects
R8366 T10759 T10760 amod several,pathways
R8367 T10866 T10865 pobj BMPs,of
R8368 T10867 T10866 cc and,BMPs
R8369 T10868 T10869 advmod even,cross-talk
R8370 T10760 T10758 pobj pathways,of
R8371 T10869 T10862 npadvmod cross-talk,mediated
R8372 T10870 T10869 prep between,cross-talk
R8373 T10871 T10872 det these,pathways
R8374 T10761 T10761 ROOT is,is
R8375 T10872 T10870 pobj pathways,between
R8376 T10873 T10875 aux has,reported
R8377 T10874 T10875 auxpass been,reported
R8378 T10762 T10761 acomp possible,is
R8379 T10875 T10857 conj reported,represent
R8380 T10876 T10878 compound [,]
R8381 T10763 T10761 punct .,is
R8382 T10877 T10878 compound "29,30",]
R8383 T10878 T10875 oprd ],reported
R8384 T10879 T10857 punct .,represent
R8385 T10764 T10767 det The,pathway
R8386 T10880 T10886 prep In,were
R8387 T10881 T10883 det the,study
R8388 T10882 T10883 amod present,study
R8389 T10765 T10767 amod major,pathway
R8390 T10883 T10880 pobj study,In
R8391 T10884 T10886 punct ",",were
R8392 T10885 T10886 nsubj we,were
R8393 T10766 T10767 amod signalling,pathway
R8394 T10886 T10886 ROOT were,were
R8395 T10887 T10886 neg not,were
R8396 T10888 T10886 acomp able,were
R8397 T10767 T10772 nsubj pathway,is
R8398 T10889 T10890 aux to,detect
R8399 T10890 T10888 xcomp detect,able
R8400 T10891 T10892 amod BMP-6-induced,changes
R8401 T10768 T10767 acl known,pathway
R8402 T10892 T10890 dobj changes,detect
R8403 T10893 T10890 prep in,detect
R8404 T10894 T10896 det the,status
R8405 T10895 T10896 compound phosphorylation,status
R8406 T10769 T10768 prep to,known
R8407 T10896 T10893 pobj status,in
R8408 T10897 T10896 prep of,status
R8409 T10770 T10769 pobj date,to
R8410 T10898 T10897 pobj STAT3,of
R8411 T10899 T10898 cc or,STAT3
R8412 T10771 T10767 punct ",",pathway
R8413 T10900 T10898 conj p38,STAT3
R8414 T10901 T10896 prep in,status
R8415 T10902 T10905 amod human,cells
R8416 T10772 T10772 ROOT is,is
R8417 T10903 T10905 amod peripheral,cells
R8418 T10904 T10905 compound B,cells
R8419 T10773 T10772 attr activation,is
R8420 T10905 T10901 pobj cells,in
R8421 T10906 T10886 punct .,were
R8422 T10907 T10917 advmod Instead,revealed
R8423 T10774 T10773 prep of,activation
R8424 T10908 T10917 punct ",",revealed
R8425 T10909 T10913 det a,phosphorylation
R8426 T10775 T10774 pobj R-Smads,of
R8427 T10910 T10913 amod rapid,phosphorylation
R8428 T10911 T10910 cc and,rapid
R8429 T10912 T10910 conj marked,rapid
R8430 T10776 T10778 compound [,]
R8431 T10913 T10917 nsubjpass phosphorylation,revealed
R8432 T10914 T10913 prep of,phosphorylation
R8433 T10915 T10914 pobj Smad1/5/8,of
R8434 T10777 T10778 compound "13,27",]
R8435 T10778 T10773 appos ],activation
R8436 T10916 T10917 auxpass was,revealed
R8437 T10779 T10772 punct .,is
R8438 T10917 T10917 ROOT revealed,revealed
R8439 T10918 T10917 punct .,revealed
R8440 T10780 T10787 prep In,shown
R8441 T10919 T10926 prep In,found
R8442 T10920 T10922 det a,study
R8443 T10921 T10922 amod parallel,study
R8444 T10781 T10782 det that,respect
R8445 T10922 T10919 pobj study,In
R8446 T10923 T10926 punct ",",found
R8447 T10782 T10780 pobj respect,In
R8448 T10924 T10926 nsubj we,found
R8449 T10925 T10926 aux have,found
R8450 T10783 T10787 punct ",",shown
R8451 T10926 T10926 ROOT found,found
R8452 T10927 T10931 mark that,induced
R8453 T10784 T10787 nsubjpass BMPs,shown
R8454 T10928 T10929 amod other,BMPs
R8455 T10929 T10931 nsubj BMPs,induced
R8456 T10785 T10787 aux have,shown
R8457 T10930 T10931 advmod also,induced
R8458 T10786 T10787 auxpass been,shown
R8459 T10787 T10787 ROOT shown,shown
R8460 T10788 T10789 aux to,exert
R8461 T10931 T10926 ccomp induced,found
R8462 T10932 T10931 dobj phosphorylation,induced
R8463 T10933 T10932 prep of,phosphorylation
R8464 T10934 T10933 pobj Smad1/5/8,of
R8465 T10789 T10787 xcomp exert,shown
R8466 T10935 T10932 prep in,phosphorylation
R8467 T10936 T10938 amod peripheral,cells
R8468 T10790 T10791 amod antiproliferative,effects
R8469 T10937 T10938 compound B,cells
R8470 T10938 T10935 pobj cells,in
R8471 T10939 T10942 punct (,shown
R8472 T10791 T10789 dobj effects,exert
R8473 T10940 T10942 nsubjpass data,shown
R8474 T10941 T10942 neg not,shown
R8475 T10942 T10931 parataxis shown,induced
R8476 T10792 T10791 prep in,effects
R8477 T10943 T10942 punct ),shown
R8478 T10944 T10926 punct .,found
R8479 T10793 T10794 compound B,lineage
R8480 T10945 T10948 nsubj We,pursuing
R8481 T10946 T10948 aux are,pursuing
R8482 T10947 T10948 advmod currently,pursuing
R8483 T10794 T10795 compound lineage,cells
R8484 T10948 T10948 ROOT pursuing,pursuing
R8485 T10949 T10950 compound microarray,studies
R8486 T10795 T10792 pobj cells,in
R8487 T10950 T10948 dobj studies,pursuing
R8488 T10951 T10952 aux to,identify
R8489 T10952 T10948 advcl identify,pursuing
R8490 T10796 T10789 prep via,exert
R8491 T10953 T10955 det the,pathways
R8492 T10954 T10955 amod signalling,pathways
R8493 T10955 T10952 dobj pathways,identify
R8494 T10797 T10796 pobj phosphorylation,via
R8495 T10956 T10955 cc and,pathways
R8496 T10957 T10958 compound target,genes
R8497 T10958 T10955 conj genes,pathways
R8498 T10798 T10797 prep of,phosphorylation
R8499 T10959 T10962 nsubjpass that,regulated
R8500 T10960 T10962 auxpass are,regulated
R8501 T10961 T10962 advmod differently,regulated
R8502 T10962 T10955 relcl regulated,pathways
R8503 T10799 T10802 amod R-Smad,]
R8504 T10963 T10962 agent by,regulated
R8505 T10964 T10966 det the,BMPs
R8506 T10800 T10802 compound [,]
R8507 T10965 T10966 amod various,BMPs
R8508 T10966 T10963 pobj BMPs,by
R8509 T10967 T10966 prep in,BMPs
R8510 T10801 T10802 compound "11,28",]
R8511 T10968 T10970 amod human,cells
R8512 T10969 T10970 compound B,cells
R8513 T10970 T10967 pobj cells,in
R8514 T10971 T10948 punct .,pursuing
R8515 T10972 T10978 nsubj Upregulation,is
R8516 T10973 T10972 prep of,Upregulation
R8517 T10802 T10798 pobj ],of
R8518 T10974 T10973 pobj Id1,of
R8519 T10975 T10972 prep via,Upregulation
R8520 T10976 T10977 compound Smad1/5/8,phosphorylation
R8521 T10803 T10787 punct .,shown
R8522 T10977 T10975 pobj phosphorylation,via
R8523 T10978 T10978 ROOT is,is
R8524 T10804 T10809 advmod Furthermore,shown
R8525 T10805 T10809 punct ",",shown
R8526 T10979 T10981 det a,mechanism
R8527 T10980 T10981 amod known,mechanism
R8528 T10806 T10809 nsubjpass BMP-2,shown
R8529 T10981 T10978 attr mechanism,is
R8530 T10982 T10981 prep for,mechanism
R8531 T10807 T10809 aux has,shown
R8532 T10983 T10984 nsubj BMP-6,signalling
R8533 T10984 T10982 pcomp signalling,for
R8534 T10985 T10984 prep in,signalling
R8535 T10808 T10809 auxpass been,shown
R8536 T10986 T10988 amod other,systems
R8537 T10987 T10988 compound cell,systems
R8538 T10988 T10985 pobj systems,in
R8539 T10809 T10809 ROOT shown,shown
R8540 T10989 T10991 compound [,]
R8541 T10990 T10991 compound "31,32",]
R8542 T10991 T10984 dobj ],signalling
R8543 T10810 T10811 aux to,induce
R8544 T10992 T10991 cc and,]
R8545 T10993 T10991 conj regulation,]
R8546 T10811 T10809 xcomp induce,shown
R8547 T10812 T10811 dobj activation,induce
R8548 T10813 T10812 prep of,activation
R8549 T10994 T10993 prep of,regulation
R8550 T10995 T10994 pobj Id-proteins,of
R8551 T10814 T10813 pobj STAT3,of
R8552 T10996 T10997 auxpass is,thought
R8553 T10997 T10978 conj thought,is
R8554 T10815 T10812 prep in,activation
R8555 T10998 T10999 aux to,be
R8556 T10999 T10997 xcomp be,thought
R8557 T11000 T11002 det an,mechanism
R8558 T10816 T10817 compound myeloma,cells
R8559 T11001 T11002 amod important,mechanism
R8560 T11002 T10999 attr mechanism,be
R8561 T11003 T11002 prep for,mechanism
R8562 T10817 T10815 pobj cells,in
R8563 T11004 T11005 compound Smad-signalling,[
R8564 T11005 T11007 nmod [,]
R8565 T11006 T11007 nummod 17,]
R8566 T11007 T11003 pobj ],for
R8567 T11008 T10978 punct .,is
R8568 T11009 T11017 prep In,revealed
R8569 T10818 T10820 nmod [,]
R8570 T11010 T11012 det the,study
R8571 T11011 T11012 amod present,study
R8572 T11012 T11009 pobj study,In
R8573 T10819 T10820 nummod 9,]
R8574 T11013 T11017 punct ",",revealed
R8575 T11014 T11016 amod real-time,experiments
R8576 T10820 T10809 dobj ],shown
R8577 T11015 T11016 compound RT-PCR,experiments
R8578 T11016 T11017 nsubj experiments,revealed
R8579 T11017 T11017 ROOT revealed,revealed
R8580 T10821 T10809 punct .,shown
R8581 T11018 T11021 det a,upregulation
R8582 T11019 T11021 amod specific,upregulation
R8583 T11020 T11021 advmod four-fold,upregulation
R8584 T10822 T10829 advmod However,investigated
R8585 T11021 T11017 dobj upregulation,revealed
R8586 T11022 T11021 prep for,upregulation
R8587 T11023 T11022 pobj Id1,for
R8588 T10823 T10829 punct ",",investigated
R8589 T11024 T11021 prep in,upregulation
R8590 T11025 T11026 compound BMP-6-treated,B
R8591 T11026 T11027 compound B,cells
R8592 T10824 T10829 nsubjpass phosphorylation,investigated
R8593 T11027 T11024 pobj cells,in
R8594 T10825 T10824 prep of,phosphorylation
R8595 T10826 T10825 pobj R-Smad,of
R8596 T10827 T10829 auxpass was,investigated
R8597 T11028 T11017 punct ",",revealed
R8598 T11029 T11035 mark while,remained
R8599 T10828 T10829 neg not,investigated
R8600 T11030 T11031 det the,amount
R8601 T11031 T11035 nsubj amount,remained
R8602 T10829 T10829 ROOT investigated,investigated
R8603 T11032 T11031 prep of,amount
R8604 T11033 T11032 pobj Id2,of
R8605 T11034 T11035 nsubj Id4,remained
R8606 T10830 T10829 prep in,investigated
R8607 T11035 T11017 advcl remained,revealed
R8608 T11036 T11035 acomp unchanged,remained
R8609 T10831 T10832 det that,study
R8610 T11037 T11017 punct .,revealed
R8611 T11038 T11046 prep In,demonstrated
R8612 T11039 T11038 pobj agreement,In
R8613 T11040 T11039 prep with,agreement
R8614 T11041 T11040 pobj this,with
R8615 T11042 T11046 punct ",",demonstrated
R8616 T11043 T11045 amod western,analysis
R8617 T11044 T11045 compound blot,analysis
R8618 T10832 T10830 pobj study,in
R8619 T11045 T11046 nsubj analysis,demonstrated
R8620 T11046 T11046 ROOT demonstrated,demonstrated
R8621 T11047 T11048 det an,upregulation
R8622 T10833 T10829 punct .,investigated
R8623 T11048 T11046 dobj upregulation,demonstrated
R8624 T11049 T11048 prep of,upregulation
R8625 T11050 T11051 amod Id1,protein
R8626 T11051 T11049 pobj protein,of
R8627 T11125 T11123 pobj interest,of
R8628 T11052 T11046 punct ",",demonstrated
R8629 T11053 T11062 mark while,remained
R8630 T11054 T11055 det the,amount
R8631 T11055 T11062 nsubj amount,remained
R8632 T11056 T11055 prep of,amount
R8633 T11126 T11122 punct .,is
R8634 T11057 T11056 pobj Id2,of
R8635 T11127 T11132 prep In,is
R8636 T11058 T11057 cc and,Id2
R8637 T11128 T11129 det that,respect
R8638 T11059 T11057 conj Id3,Id2
R8639 T11060 T11061 compound protein,levels
R8640 T11061 T11062 nsubj levels,remained
R8641 T11129 T11127 pobj respect,In
R8642 T11062 T11046 advcl remained,demonstrated
R8643 T11063 T11062 acomp unchanged,remained
R8644 T11130 T11132 punct ",",is
R8645 T11064 T11046 punct .,demonstrated
R8646 T11065 T11070 advmod Previously,considered
R8647 T11131 T11132 nsubj it,is
R8648 T11066 T11070 punct ",",considered
R8649 T11067 T11070 nsubjpass Id1,considered
R8650 T11068 T11070 aux has,considered
R8651 T11132 T11132 ROOT is,is
R8652 T11069 T11070 auxpass been,considered
R8653 T11070 T11070 ROOT considered,considered
R8654 T11133 T11132 acomp noteworthy,is
R8655 T11071 T11074 neg not,expressed
R8656 T11072 T11074 aux to,expressed
R8657 T11134 T11143 mark that,induces
R8658 T11135 T11136 amod TGF-β,signalling
R8659 T11073 T11074 auxpass be,expressed
R8660 T11074 T11070 xcomp expressed,considered
R8661 T11075 T11074 prep in,expressed
R8662 T11136 T11143 nsubj signalling,induces
R8663 T11076 T11078 amod later,stages
R8664 T11077 T11078 amod developmental,stages
R8665 T11078 T11075 pobj stages,in
R8666 T11079 T11074 prep than,expressed
R8667 T11080 T11081 amod pro-B,cells
R8668 T11081 T11079 pobj cells,than
R8669 T11137 T11136 prep in,signalling
R8670 T11082 T11084 compound [,]
R8671 T11083 T11084 compound "33,34",]
R8672 T11084 T11081 appos ],cells
R8673 T11138 T11142 amod early,cells
R8674 T11085 T11084 punct ",",]
R8675 T11086 T11084 cc and,]
R8676 T11139 T11138 cc and,early
R8677 T11087 T11089 poss its,expression
R8678 T11088 T11089 amod constitutive,expression
R8679 T11089 T11092 nsubjpass expression,reported
R8680 T11140 T11138 conj mature,early
R8681 T11090 T11092 aux has,reported
R8682 T11091 T11092 auxpass been,reported
R8683 T11141 T11142 compound B,cells
R8684 T11092 T11070 conj reported,considered
R8685 T11093 T11094 aux to,impair
R8686 T11094 T11092 xcomp impair,reported
R8687 T11095 T11098 compound mouse,development
R8688 T11142 T11137 pobj cells,in
R8689 T11096 T11098 compound B,development
R8690 T11097 T11098 compound cell,development
R8691 T11098 T11094 dobj development,impair
R8692 T11143 T11132 ccomp induces,is
R8693 T11099 T11101 nmod [,]
R8694 T11100 T11101 nummod 35,]
R8695 T11144 T11145 preconj both,Id2
R8696 T11101 T11098 appos ],development
R8697 T11102 T11092 punct .,reported
R8698 T11103 T11122 advmod Therefore,is
R8699 T11145 T11148 amod Id2,expression
R8700 T11104 T11122 punct ",",is
R8701 T11105 T11106 poss our,demonstration
R8702 T11146 T11145 cc and,Id2
R8703 T11106 T11122 nsubj demonstration,is
R8704 T11107 T11106 prep of,demonstration
R8705 T11108 T11110 det the,upregulation
R8706 T11147 T11145 conj Id3,Id2
R8707 T11109 T11110 amod time-dependent,upregulation
R8708 T11110 T11107 pobj upregulation,of
R8709 T11111 T11110 prep of,upregulation
R8710 T11112 T11113 compound Id1,mRNA
R8711 T11148 T11151 compound expression,]
R8712 T11149 T11151 compound [,]
R8713 T11113 T11111 pobj mRNA,of
R8714 T11150 T11151 compound "36,37",]
R8715 T11114 T11110 cc and,upregulation
R8716 T11115 T11110 conj protein,upregulation
R8717 T11116 T11110 prep in,upregulation
R8718 T11117 T11121 amod mature,cells
R8719 T11118 T11121 amod normal,cells
R8720 T11151 T11143 dobj ],induces
R8721 T11119 T11121 amod human,cells
R8722 T11120 T11121 compound B,cells
R8723 T11121 T11116 pobj cells,in
R8724 T11122 T11122 ROOT is,is
R8725 T11152 T11143 punct ",",induces
R8726 T11123 T11122 prep of,is
R8727 T11124 T11125 amod particular,interest
R8728 T11153 T11143 cc but,induces
R8729 T11154 T11155 neg not,Id1
R8730 T11155 T11143 conj Id1,induces
R8731 T11156 T11159 punct (,shown
R8732 T11222 T11203 punct .,found
R8733 T11157 T11159 nsubjpass data,shown
R8734 T11223 T11228 advmod However,induce
R8735 T11224 T11228 punct ",",induce
R8736 T11158 T11159 neg not,shown
R8737 T11225 T11228 nsubj BMP-6,induce
R8738 T11159 T11155 parataxis shown,Id1
R8739 T11226 T11228 aux did,induce
R8740 T11227 T11228 neg not,induce
R8741 T11228 T11228 ROOT induce,induce
R8742 T11160 T11159 punct ),shown
R8743 T11229 T11230 amod significant,changes
R8744 T11230 T11228 dobj changes,induce
R8745 T11161 T11132 punct .,is
R8746 T11231 T11230 prep in,changes
R8747 T11232 T11234 det the,expression
R8748 T11162 T11166 advmod Interestingly,show
R8749 T11233 T11234 compound protein,expression
R8750 T11234 T11231 pobj expression,in
R8751 T11235 T11234 prep of,expression
R8752 T11163 T11166 punct ",",show
R8753 T11236 T11235 pobj Id2,of
R8754 T11237 T11236 cc and,Id2
R8755 T11238 T11236 conj Id3,Id2
R8756 T11164 T11165 det these,results
R8757 T11239 T11228 punct .,induce
R8758 T11240 T11242 nsubjpass It,believed
R8759 T11241 T11242 auxpass is,believed
R8760 T11165 T11166 nsubj results,show
R8761 T11242 T11242 ROOT believed,believed
R8762 T11243 T11246 mark that,block
R8763 T11244 T11246 advmod Id,block
R8764 T11166 T11166 ROOT show,show
R8765 T11245 T11246 nsubj proteins,block
R8766 T11246 T11242 ccomp block,believed
R8767 T11247 T11246 dobj differentiation,block
R8768 T11248 T11246 cc and,block
R8769 T11249 T11246 conj promote,block
R8770 T11250 T11249 dobj proliferation,promote
R8771 T11167 T11174 mark that,regulate
R8772 T11251 T11249 prep in,promote
R8773 T11252 T11254 amod various,types
R8774 T11168 T11169 amod various,members
R8775 T11253 T11254 compound cell,types
R8776 T11254 T11251 pobj types,in
R8777 T11255 T11257 compound [,]
R8778 T11169 T11174 nsubj members,regulate
R8779 T11256 T11257 compound "39,33",]
R8780 T11257 T11246 npadvmod ],block
R8781 T11258 T11242 punct .,believed
R8782 T11170 T11169 prep of,members
R8783 T11259 T11261 advmod Id,act
R8784 T11260 T11261 nsubj proteins,act
R8785 T11171 T11173 det the,family
R8786 T11261 T11261 ROOT act,act
R8787 T11262 T11261 prep as,act
R8788 T11263 T11264 amod dominant-negative,inhibitors
R8789 T11264 T11262 pobj inhibitors,as
R8790 T11172 T11173 compound TGF-β,family
R8791 T11265 T11264 prep of,inhibitors
R8792 T11266 T11265 pobj E-proteins,of
R8793 T11173 T11170 pobj family,of
R8794 T11267 T11266 cc and,E-proteins
R8795 T11268 T11266 conj Pax5,E-proteins
R8796 T11269 T11261 conj function,act
R8797 T11270 T11269 prep by,function
R8798 T11174 T11166 ccomp regulate,show
R8799 T11271 T11270 pcomp forming,by
R8800 T11272 T11271 dobj dimers,forming
R8801 T11175 T11176 compound Id,proteins
R8802 T11273 T11271 prep with,forming
R8803 T11274 T11275 det these,proteins
R8804 T11176 T11174 dobj proteins,regulate
R8805 T11275 T11273 pobj proteins,with
R8806 T11276 T11271 punct ",",forming
R8807 T11277 T11271 advcl making,forming
R8808 T11177 T11174 advmod differently,regulate
R8809 T11278 T11279 nsubj them,unable
R8810 T11279 T11277 ccomp unable,making
R8811 T11178 T11166 punct .,show
R8812 T11280 T11281 aux to,bind
R8813 T11281 T11279 xcomp bind,unable
R8814 T11282 T11281 dobj DNA,bind
R8815 T11179 T11183 nsubjpass Id2,considered
R8816 T11283 T11261 punct .,act
R8817 T11284 T11287 nsubjpass It,proposed
R8818 T11285 T11287 aux has,proposed
R8819 T11286 T11287 auxpass been,proposed
R8820 T11287 T11287 ROOT proposed,proposed
R8821 T11288 T11299 mark that,have
R8822 T11180 T11179 cc and,Id2
R8823 T11289 T11290 det the,balance
R8824 T11290 T11299 nsubj balance,have
R8825 T11291 T11290 prep among,balance
R8826 T11181 T11179 conj Id3,Id2
R8827 T11292 T11291 pobj E-proteins,among
R8828 T11293 T11292 punct ",",E-proteins
R8829 T11182 T11183 auxpass are,considered
R8830 T11294 T11292 conj Pax5,E-proteins
R8831 T11295 T11294 cc and,Pax5
R8832 T11183 T11183 ROOT considered,considered
R8833 T11296 T11297 compound Id,proteins
R8834 T11184 T11185 aux to,be
R8835 T11297 T11294 conj proteins,Pax5
R8836 T11298 T11299 aux might,have
R8837 T11185 T11183 xcomp be,considered
R8838 T11299 T11287 ccomp have,proposed
R8839 T11300 T11302 det an,role
R8840 T11186 T11188 det the,proteins
R8841 T11301 T11302 amod important,role
R8842 T11302 T11299 dobj role,have
R8843 T11303 T11302 prep in,role
R8844 T11187 T11188 compound Id,proteins
R8845 T11304 T11306 amod activated,cells
R8846 T11305 T11306 compound B,cells
R8847 T11188 T11185 attr proteins,be
R8848 T11306 T11303 pobj cells,in
R8849 T11307 T11309 nmod [,]
R8850 T11189 T11190 advmod mainly,expressed
R8851 T11190 T11188 acl expressed,proteins
R8852 T11308 T11309 nummod 38,]
R8853 T11191 T11190 prep in,expressed
R8854 T11309 T11306 appos ],cells
R8855 T11310 T11287 punct .,proposed
R8856 T11311 T11318 prep In,implicated
R8857 T11192 T11194 amod mature,cells
R8858 T11312 T11313 det that,respect
R8859 T11313 T11311 pobj respect,In
R8860 T11193 T11194 compound B,cells
R8861 T11314 T11318 punct ",",implicated
R8862 T11315 T11318 nsubjpass E-proteins,implicated
R8863 T11316 T11318 aux have,implicated
R8864 T11194 T11191 pobj cells,in
R8865 T11317 T11318 auxpass been,implicated
R8866 T11318 T11318 ROOT implicated,implicated
R8867 T11195 T11197 nmod [,]
R8868 T11196 T11197 nummod 38,]
R8869 T11319 T11318 prep in,implicated
R8870 T11320 T11322 preconj both,promotion
R8871 T11197 T11194 appos ],cells
R8872 T11321 T11322 det the,promotion
R8873 T11322 T11319 pobj promotion,in
R8874 T11323 T11322 cc and,promotion
R8875 T11198 T11183 punct .,considered
R8876 T11324 T11322 conj inhibition,promotion
R8877 T11325 T11324 prep of,inhibition
R8878 T11326 T11327 compound cell,survival
R8879 T11199 T11201 det The,study
R8880 T11327 T11325 pobj survival,of
R8881 T11328 T11327 cc and,survival
R8882 T11200 T11201 amod present,study
R8883 T11329 T11327 conj growth,survival
R8884 T11330 T11322 prep at,promotion
R8885 T11331 T11332 amod different,points
R8886 T11201 T11203 nsubj study,found
R8887 T11332 T11330 pobj points,at
R8888 T11333 T11322 prep in,promotion
R8889 T11202 T11203 advmod also,found
R8890 T11334 T11335 compound lymphocyte,development
R8891 T11335 T11333 pobj development,in
R8892 T11336 T11338 nmod [,]
R8893 T11203 T11203 ROOT found,found
R8894 T11337 T11338 nummod 40,]
R8895 T11338 T11322 appos ],promotion
R8896 T11339 T11318 punct .,implicated
R8897 T11204 T11203 dobj Id2,found
R8898 T11340 T11341 det The,antiproliferative
R8899 T11341 T11344 nsubj antiproliferative,inducing
R8900 T11205 T11204 cc and,Id2
R8901 T11342 T11341 cc and,antiproliferative
R8902 T11343 T11344 npadvmod death,inducing
R8903 T11344 T11357 csubj inducing,is
R8904 T11206 T11207 compound Id3,protein
R8905 T11345 T11344 dobj effect,inducing
R8906 T11346 T11345 prep of,effect
R8907 T11347 T11346 pobj BMP-6,of
R8908 T11207 T11204 conj protein,Id2
R8909 T11348 T11344 prep in,inducing
R8910 T11349 T11350 compound B,cells
R8911 T11350 T11348 pobj cells,in
R8912 T11208 T11203 prep in,found
R8913 T11351 T11344 prep with,inducing
R8914 T11352 T11353 amod concomitant,upregulation
R8915 T11353 T11351 pobj upregulation,with
R8916 T11354 T11353 prep of,upregulation
R8917 T11355 T11356 amod Id1,protein
R8918 T11209 T11210 compound B,cells
R8919 T11356 T11354 pobj protein,of
R8920 T11357 T11357 ROOT is,is
R8921 T11358 T11359 advmod therefore,in
R8922 T11210 T11208 pobj cells,in
R8923 T11359 T11357 prep in,is
R8924 T11360 T11359 pobj line,in
R8925 T11211 T11212 aux to,be
R8926 T11361 T11360 prep with,line
R8927 T11362 T11363 det the,view
R8928 T11363 T11361 pobj view,with
R8929 T11212 T11203 advcl be,found
R8930 T11364 T11368 mark that,required
R8931 T11365 T11368 prep Id,required
R8932 T11366 T11368 nsubjpass proteins,required
R8933 T11213 T11215 advmod more,expressed
R8934 T11367 T11368 auxpass are,required
R8935 T11368 T11363 acl required,view
R8936 T11369 T11368 prep for,required
R8937 T11214 T11215 advmod highly,expressed
R8938 T11370 T11371 det the,induction
R8939 T11371 T11369 pobj induction,for
R8940 T11372 T11371 prep of,induction
R8941 T11215 T11212 acomp expressed,be
R8942 T11373 T11374 compound growth,arrest
R8943 T11374 T11372 pobj arrest,of
R8944 T11216 T11215 prep than,expressed
R8945 T11375 T11374 cc and,arrest
R8946 T11376 T11374 conj apoptosis,arrest
R8947 T11217 T11216 pobj Id1,than
R8948 T11218 T11217 prep in,Id1
R8949 T11377 T11371 prep in,induction
R8950 T11219 T11218 pcomp resting,in
R8951 T11378 T11379 amod B-lymphocyte,progenitors
R8952 T11379 T11377 pobj progenitors,in
R8953 T11220 T11221 compound B,cells
R8954 T11380 T11371 prep by,induction
R8955 T11381 T11382 compound TGF-β,[
R8956 T11382 T11380 pobj [,by
R8957 T11221 T11219 dobj cells,resting
R8958 T11383 T11384 nummod 40,]
R8959 T11384 T11382 appos ],[
R8960 T11385 T11357 punct .,is
R8961 T11416 T11422 nsubjpass members,overexpressed
R8962 T11386 T11391 advmod Furthermore,known
R8963 T11417 T11416 prep of,members
R8964 T11387 T11391 punct ",",known
R8965 T11388 T11391 advmod Id,known
R8966 T11418 T11420 det the,family
R8967 T11389 T11391 nsubjpass proteins,known
R8968 T11390 T11391 auxpass are,known
R8969 T11391 T11391 ROOT known,known
R8970 T11392 T11391 prep as,known
R8971 T11393 T11394 amod important,parts
R8972 T11419 T11420 compound Id,family
R8973 T11394 T11392 pobj parts,as
R8974 T11395 T11394 prep of,parts
R8975 T11396 T11395 pcomp signalling,of
R8976 T11420 T11417 pobj family,of
R8977 T11397 T11396 dobj pathways,signalling
R8978 T11398 T11397 acl involved,pathways
R8979 T11399 T11398 prep in,involved
R8980 T11421 T11422 auxpass are,overexpressed
R8981 T11400 T11399 pobj development,in
R8982 T11401 T11400 punct ",",development
R8983 T11402 T11403 compound cell,cycle
R8984 T11422 T11413 ccomp overexpressed,established
R8985 T11403 T11400 conj cycle,development
R8986 T11404 T11403 cc and,cycle
R8987 T11405 T11406 compound tumorigenesis,[
R8988 T11423 T11422 prep in,overexpressed
R8989 T11406 T11406 ROOT [,[
R8990 T11407 T11408 nummod 32,]
R8991 T11408 T11391 dobj ],known
R8992 T11424 T11425 det a,range
R8993 T11409 T11391 punct .,known
R8994 T11410 T11413 nsubjpass It,established
R8995 T11425 T11423 pobj range,in
R8996 T11411 T11413 auxpass is,established
R8997 T11412 T11413 advmod well,established
R8998 T11413 T11413 ROOT established,established
R8999 T11426 T11425 prep of,range
R9000 T11414 T11422 mark that,overexpressed
R9001 T11415 T11416 amod various,members
R9002 T11427 T11428 amod human,tumours
R9003 T11428 T11426 pobj tumours,of
R9004 T11429 T11428 cc and,tumours
R9005 T11439 T11440 advmod most,widely
R9006 T11430 T11433 advmod generally,appears
R9007 T11440 T11441 advmod widely,overexpressed
R9008 T11441 T11435 attr overexpressed,be
R9009 T11442 T11441 prep in,overexpressed
R9010 T11443 T11444 det a,variety
R9011 T11431 T11433 punct ",",appears
R9012 T11444 T11442 pobj variety,in
R9013 T11432 T11433 nsubj Id1,appears
R9014 T11433 T11413 conj appears,established
R9015 T11445 T11444 prep of,variety
R9016 T11434 T11435 aux to,be
R9017 T11446 T11447 amod human,malignancies
R9018 T11447 T11445 pobj malignancies,of
R9019 T11448 T11450 nmod [,]
R9020 T11449 T11450 nummod 41,]
R9021 T11450 T11444 appos ],variety
R9022 T11435 T11433 xcomp be,appears
R9023 T11451 T11444 punct ",",variety
R9024 T11452 T11444 prep including,variety
R9025 T11453 T11455 amod multiple,[
R9026 T11436 T11438 det the,member
R9027 T11454 T11455 compound myeloma,[
R9028 T11455 T11452 pobj [,including
R9029 T11437 T11438 compound family,member
R9030 T11438 T11441 nsubj member,overexpressed
R9031 T11456 T11457 nummod "42,32",]
R9032 T11514 T11513 pobj Id1,of
R9033 T11457 T11455 acl ],[
R9034 T11458 T11433 punct .,appears
R9035 T11459 T11474 advmod Additionally,be
R9036 T11460 T11474 punct ",",be
R9037 T11515 T11512 prep to,expression
R9038 T11461 T11462 poss our,findings
R9039 T11462 T11474 nsubj findings,be
R9040 T11516 T11515 pobj B-lymphocytes,to
R9041 T11463 T11465 dobj that,activates
R9042 T11464 T11465 nsubj BMP-6,activates
R9043 T11517 T11507 ccomp resulted,is
R9044 T11465 T11462 relcl activates,findings
R9045 T11466 T11468 amod intracellular,pathways
R9046 T11467 T11468 amod signalling,pathways
R9047 T11518 T11517 prep in,resulted
R9048 T11468 T11465 dobj pathways,activates
R9049 T11469 T11468 prep in,pathways
R9050 T11470 T11472 amod human,cells
R9051 T11519 T11522 amod aberrant,development
R9052 T11471 T11472 compound B,cells
R9053 T11472 T11469 pobj cells,in
R9054 T11473 T11474 aux might,be
R9055 T11520 T11521 compound B,cell
R9056 T11474 T11474 ROOT be,be
R9057 T11475 T11474 prep of,be
R9058 T11476 T11478 amod potential,significance
R9059 T11521 T11522 compound cell,development
R9060 T11477 T11478 amod pathophysiological,significance
R9061 T11478 T11475 pobj significance,of
R9062 T11479 T11478 prep in,significance
R9063 T11522 T11518 pobj development,in
R9064 T11480 T11479 pobj lymphoma,in
R9065 T11481 T11480 cc and,lymphoma
R9066 T11523 T11522 punct ",",development
R9067 T11482 T11480 conj inflammation,lymphoma
R9068 T11483 T11474 punct .,be
R9069 T11484 T11486 compound High,mRNA
R9070 T11485 T11486 compound BMP-6,mRNA
R9071 T11486 T11487 compound mRNA,expression
R9072 T11487 T11492 nsubjpass expression,shown
R9073 T11524 T11525 amod massive,apoptosis
R9074 T11488 T11487 prep in,expression
R9075 T11489 T11488 pobj DLBCL,in
R9076 T11490 T11492 aux has,shown
R9077 T11491 T11492 auxpass been,shown
R9078 T11525 T11522 conj apoptosis,development
R9079 T11492 T11492 ROOT shown,shown
R9080 T11493 T11494 aux to,correlate
R9081 T11494 T11492 xcomp correlate,shown
R9082 T11526 T11517 punct ",",resulted
R9083 T11495 T11494 prep to,correlate
R9084 T11496 T11497 amod unfavourable,outcome
R9085 T11497 T11495 pobj outcome,to
R9086 T11527 T11517 cc and,resulted
R9087 T11498 T11500 nmod [,]
R9088 T11499 T11500 nummod 12,]
R9089 T11500 T11495 pobj ],to
R9090 T11528 T11529 amod subsequent,development
R9091 T11501 T11492 punct .,shown
R9092 T11502 T11507 prep In,is
R9093 T11503 T11504 det this,respect
R9094 T11529 T11536 nmod development,]
R9095 T11504 T11502 pobj respect,In
R9096 T11505 T11507 punct ",",is
R9097 T11506 T11507 nsubj it,is
R9098 T11530 T11529 prep of,development
R9099 T11507 T11507 ROOT is,is
R9100 T11508 T11507 prep of,is
R9101 T11509 T11508 pobj interest,of
R9102 T11531 T11532 compound B,cell
R9103 T11510 T11517 dobj that,resulted
R9104 T11511 T11512 amod targeted,expression
R9105 T11512 T11517 nsubj expression,resulted
R9106 T11532 T11533 compound cell,lymphomas
R9107 T11513 T11512 prep of,expression
R9108 T11533 T11530 pobj lymphomas,of
R9109 T11534 T11536 nmod [,]
R9110 T11613 T11609 xcomp elucidate,be
R9111 T11535 T11536 nummod 35,]
R9112 T11536 T11507 npadvmod ],is
R9113 T11614 T11615 det the,role
R9114 T11537 T11507 punct .,is
R9115 T11538 T11543 advmod Moreover,suggested
R9116 T11539 T11543 punct ",",suggested
R9117 T11540 T11543 nsubjpass BMP-6,suggested
R9118 T11541 T11543 aux has,suggested
R9119 T11542 T11543 auxpass been,suggested
R9120 T11615 T11613 dobj role,elucidate
R9121 T11543 T11543 ROOT suggested,suggested
R9122 T11616 T11615 prep of,role
R9123 T11617 T11616 pobj Id-1,of
R9124 T11618 T11617 prep in,Id-1
R9125 T11544 T11545 aux to,play
R9126 T11619 T11621 amod human,cells
R9127 T11545 T11543 xcomp play,suggested
R9128 T11620 T11621 compound B,cells
R9129 T11546 T11547 det a,role
R9130 T11547 T11545 dobj role,play
R9131 T11621 T11618 pobj cells,in
R9132 T11548 T11547 prep in,role
R9133 T11549 T11550 amod rheumatoid,arthritis
R9134 T11550 T11548 pobj arthritis,in
R9135 T11622 T11613 prep by,elucidate
R9136 T11551 T11552 punct (,RA
R9137 T11552 T11550 appos RA,arthritis
R9138 T11623 T11622 pobj selective,by
R9139 T11553 T11543 punct ),suggested
R9140 T11554 T11556 compound [,]
R9141 T11555 T11556 compound "43,44",]
R9142 T11556 T11566 nsubjpass ],found
R9143 T11624 T11623 prt over,selective
R9144 T11557 T11556 cc and,]
R9145 T11558 T11559 amod elevated,levels
R9146 T11559 T11556 conj levels,]
R9147 T11625 T11624 pobj expression,over
R9148 T11560 T11559 prep of,levels
R9149 T11561 T11560 pobj Id1,of
R9150 T11562 T11561 cc and,Id1
R9151 T11626 T11625 cc or,expression
R9152 T11563 T11561 conj Id3,Id1
R9153 T11564 T11566 aux have,found
R9154 T11627 T11625 conj inhibition,expression
R9155 T11565 T11566 auxpass been,found
R9156 T11566 T11566 ROOT found,found
R9157 T11567 T11566 prep in,found
R9158 T11628 T11625 prep of,expression
R9159 T11568 T11569 det the,synovia
R9160 T11569 T11567 pobj synovia,in
R9161 T11570 T11569 prep of,synovia
R9162 T11629 T11631 amod Id-1,expression
R9163 T11571 T11570 pobj RA-patients,of
R9164 T11572 T11574 quantmod [,]
R9165 T11573 T11574 nummod 45,]
R9166 T11630 T11631 compound gene,expression
R9167 T11574 T11569 appos ],synovia
R9168 T11575 T11566 punct .,found
R9169 T11576 T11580 advmod Altogether,point
R9170 T11577 T11580 punct ",",point
R9171 T11578 T11579 det these,results
R9172 T11579 T11580 nsubj results,point
R9173 T11631 T11628 pobj expression,of
R9174 T11580 T11580 ROOT point,point
R9175 T11581 T11580 prep to,point
R9176 T11582 T11584 det an,role
R9177 T11583 T11584 amod important,role
R9178 T11632 T11609 punct .,be
R9179 T11584 T11581 pobj role,to
R9180 T11585 T11584 prep for,role
R9181 T11633 T11643 prep Given,demonstrated
R9182 T11586 T11587 compound Id,proteins
R9183 T11587 T11585 pobj proteins,for
R9184 T11588 T11584 prep in,role
R9185 T11589 T11590 det the,regulation
R9186 T11634 T11635 det the,role
R9187 T11590 T11588 pobj regulation,in
R9188 T11591 T11590 prep of,regulation
R9189 T11592 T11595 amod normal,homeostasis
R9190 T11635 T11633 pobj role,Given
R9191 T11593 T11594 compound B,cell
R9192 T11594 T11595 compound cell,homeostasis
R9193 T11595 T11591 pobj homeostasis,of
R9194 T11596 T11588 cc and,in
R9195 T11636 T11635 prep of,role
R9196 T11597 T11588 conj in,in
R9197 T11598 T11597 pobj diseases,in
R9198 T11637 T11636 pobj BMP-6,of
R9199 T11599 T11598 punct ",",diseases
R9200 T11600 T11604 advmod where,involved
R9201 T11601 T11602 compound B,cells
R9202 T11602 T11604 nsubjpass cells,involved
R9203 T11638 T11635 prep in,role
R9204 T11603 T11604 auxpass are,involved
R9205 T11604 T11598 relcl involved,diseases
R9206 T11605 T11580 punct .,point
R9207 T11606 T11609 nsubj It,be
R9208 T11607 T11609 aux will,be
R9209 T11639 T11642 amod mature,cells
R9210 T11608 T11609 advmod therefore,be
R9211 T11640 T11642 amod human,cells
R9212 T11609 T11609 ROOT be,be
R9213 T11610 T11609 acomp important,be
R9214 T11641 T11642 compound B,cells
R9215 T11611 T11613 aux to,elucidate
R9216 T11612 T11613 advmod further,elucidate
R9217 T11642 T11638 pobj cells,in
R9218 T11643 T11643 ROOT demonstrated,demonstrated
R9219 T11644 T11643 advmod here,demonstrated
R9220 T11645 T11643 punct ",",demonstrated
R9221 T11646 T11664 nsubj identification,contribute
R9222 T11711 T11718 punct ",",reported
R9223 T11647 T11646 prep of,identification
R9224 T11712 T11715 det an,loop
R9225 T11713 T11715 amod autocrine,loop
R9226 T11648 T11649 nsubj BMP-6,producing
R9227 T11714 T11715 compound BMP-6,loop
R9228 T11715 T11718 nsubjpass loop,reported
R9229 T11649 T11647 pcomp producing,of
R9230 T11716 T11718 aux has,reported
R9231 T11717 T11718 auxpass been,reported
R9232 T11718 T11718 ROOT reported,reported
R9233 T11650 T11649 dobj cells,producing
R9234 T11719 T11718 agent by,reported
R9235 T11720 T11719 pobj others,by
R9236 T11721 T11720 prep in,others
R9237 T11651 T11649 prep in,producing
R9238 T11722 T11721 pobj chondrocytes,in
R9239 T11723 T11721 cc and,in
R9240 T11652 T11651 pobj vivo,in
R9241 T11724 T11721 conj in,in
R9242 T11725 T11726 det the,ovarium
R9243 T11726 T11724 pobj ovarium,in
R9244 T11653 T11649 prep with,producing
R9245 T11654 T11653 pobj possibility,with
R9246 T11655 T11654 prep of,possibility
R9247 T11727 T11729 compound [,]
R9248 T11656 T11655 pobj interaction,of
R9249 T11728 T11729 compound "46,19,18",]
R9250 T11729 T11720 appos ],others
R9251 T11657 T11656 prep with,interaction
R9252 T11730 T11718 punct .,reported
R9253 T11731 T11734 advmod Therefore,wanted
R9254 T11658 T11657 pobj naïve,with
R9255 T11732 T11734 punct ",",wanted
R9256 T11733 T11734 nsubj we,wanted
R9257 T11659 T11658 cc and,naïve
R9258 T11734 T11734 ROOT wanted,wanted
R9259 T11735 T11736 aux to,explore
R9260 T11736 T11734 xcomp explore,wanted
R9261 T11660 T11662 compound memory,cells
R9262 T11737 T11738 det the,possibility
R9263 T11738 T11736 dobj possibility,explore
R9264 T11739 T11738 prep for,possibility
R9265 T11661 T11662 compound B,cells
R9266 T11740 T11743 det an,loop
R9267 T11741 T11743 amod autocrine,loop
R9268 T11742 T11743 compound BMP-6,loop
R9269 T11743 T11739 pobj loop,for
R9270 T11744 T11743 prep in,loop
R9271 T11745 T11747 amod human,cells
R9272 T11662 T11658 conj cells,naïve
R9273 T11746 T11747 compound B,cells
R9274 T11747 T11744 pobj cells,in
R9275 T11748 T11734 punct .,wanted
R9276 T11749 T11750 nsubj We,analysed
R9277 T11663 T11664 aux might,contribute
R9278 T11750 T11750 ROOT analysed,analysed
R9279 T11751 T11752 det the,expression
R9280 T11752 T11750 dobj expression,analysed
R9281 T11664 T11643 ccomp contribute,demonstrated
R9282 T11753 T11754 compound BMP-6,mRNA
R9283 T11754 T11752 appos mRNA,expression
R9284 T11755 T11750 prep in,analysed
R9285 T11665 T11664 prep to,contribute
R9286 T11756 T11759 amod peripheral,cells
R9287 T11757 T11758 compound blood,B
R9288 T11758 T11759 compound B,cells
R9289 T11666 T11667 det the,understanding
R9290 T11759 T11755 pobj cells,in
R9291 T11760 T11750 prep by,analysed
R9292 T11761 T11762 amod real-time,PCR
R9293 T11762 T11760 pobj PCR,by
R9294 T11667 T11665 pobj understanding,to
R9295 T11763 T11750 punct ",",analysed
R9296 T11764 T11750 cc and,analysed
R9297 T11668 T11667 prep of,understanding
R9298 T11765 T11750 conj report,analysed
R9299 T11669 T11672 amod mature,biology
R9300 T11766 T11765 advmod here,report
R9301 T11670 T11671 compound B,cell
R9302 T11767 T11768 det the,upregulation
R9303 T11768 T11765 dobj upregulation,report
R9304 T11769 T11768 prep of,upregulation
R9305 T11671 T11672 compound cell,biology
R9306 T11770 T11772 amod endogenous,transcripts
R9307 T11771 T11772 compound BMP-6,transcripts
R9308 T11772 T11769 pobj transcripts,of
R9309 T11672 T11668 pobj biology,of
R9310 T11773 T11768 prep after,upregulation
R9311 T11774 T11773 pobj stimulation,after
R9312 T11775 T11768 prep with,upregulation
R9313 T11673 T11643 punct .,demonstrated
R9314 T11776 T11775 pobj FCS,with
R9315 T11777 T11768 punct ",",upregulation
R9316 T11674 T11676 compound High,mRNA
R9317 T11778 T11779 compound human,AB-serum
R9318 T11779 T11768 conj AB-serum,upregulation
R9319 T11780 T11779 cc and,AB-serum
R9320 T11781 T11785 punct ",",anti-IgM
R9321 T11782 T11783 advmod most,importantly
R9322 T11783 T11785 advmod importantly,anti-IgM
R9323 T11675 T11676 compound BMP-6,mRNA
R9324 T11784 T11785 punct ",",anti-IgM
R9325 T11785 T11779 conj anti-IgM,AB-serum
R9326 T11786 T11785 punct .,anti-IgM
R9327 T11676 T11677 compound mRNA,expression
R9328 T11787 T11796 advmod However,were
R9329 T11788 T11796 punct ",",were
R9330 T11789 T11790 poss our,attempts
R9331 T11790 T11796 nsubj attempts,were
R9332 T11677 T11682 nsubjpass expression,detected
R9333 T11791 T11792 aux to,study
R9334 T11792 T11790 acl study,attempts
R9335 T11793 T11795 compound BMP-6,levels
R9336 T11678 T11677 prep in,expression
R9337 T11794 T11795 compound protein,levels
R9338 T11795 T11792 dobj levels,study
R9339 T11796 T11796 ROOT were,were
R9340 T11679 T11678 pobj DLBCL,in
R9341 T11797 T11796 acomp unsuccessful,were
R9342 T11798 T11796 acomp due,were
R9343 T11799 T11798 prep to,due
R9344 T11680 T11682 aux has,detected
R9345 T11800 T11799 pobj problems,to
R9346 T11801 T11800 prep with,problems
R9347 T11802 T11803 amod unspecific,binding
R9348 T11803 T11801 pobj binding,with
R9349 T11681 T11682 auxpass been,detected
R9350 T11804 T11803 prep of,binding
R9351 T11805 T11807 det the,antibodies
R9352 T11806 T11807 amod anti-BMP-6,antibodies
R9353 T11682 T11682 ROOT detected,detected
R9354 T11807 T11804 pobj antibodies,of
R9355 T11808 T11803 conj tested,binding
R9356 T11809 T11808 punct ",",tested
R9357 T11683 T11682 agent by,detected
R9358 T11684 T11685 compound gene,expression
R9359 T11685 T11683 pobj expression,by
R9360 T11810 T11808 cc and,tested
R9361 T11811 T11801 pobj lack,with
R9362 T11686 T11685 acl profiling,expression
R9363 T11812 T11811 prep of,lack
R9364 T11813 T11814 amod specific,staining
R9365 T11687 T11689 nmod [,]
R9366 T11814 T11812 pobj staining,of
R9367 T11815 T11814 prep in,staining
R9368 T11816 T11817 compound control,cells
R9369 T11817 T11815 pobj cells,in
R9370 T11818 T11817 acl known,cells
R9371 T11688 T11689 nummod 12,]
R9372 T11819 T11820 aux to,express
R9373 T11820 T11818 xcomp express,known
R9374 T11821 T11822 compound BMP-6,mRNA
R9375 T11689 T11686 dobj ],profiling
R9376 T11822 T11820 dobj mRNA,express
R9377 T11823 T11796 punct .,were
R9378 T11690 T11682 punct .,detected
R9379 T11824 T11832 prep In,detected
R9380 T11825 T11824 pobj contrast,In
R9381 T11826 T11832 punct ",",detected
R9382 T11691 T11703 advmod Furthermore,detected
R9383 T11827 T11829 det the,protein
R9384 T11828 T11829 compound recombinant,protein
R9385 T11692 T11703 punct ",",detected
R9386 T11829 T11832 nsubjpass protein,detected
R9387 T11830 T11832 auxpass was,detected
R9388 T11831 T11832 advmod readily,detected
R9389 T11693 T11703 nsubjpass production,detected
R9390 T11832 T11832 ROOT detected,detected
R9391 T11833 T11832 punct .,detected
R9392 T11834 T11841 prep In,detected
R9393 T11694 T11693 prep of,production
R9394 T11835 T11836 det that,respect
R9395 T11836 T11834 pobj respect,In
R9396 T11837 T11841 punct ",",detected
R9397 T11695 T11696 compound BMP-6,transcripts
R9398 T11838 T11839 amod few,investigators
R9399 T11839 T11841 nsubj investigators,detected
R9400 T11840 T11841 aux have,detected
R9401 T11696 T11694 pobj transcripts,of
R9402 T11841 T11841 ROOT detected,detected
R9403 T11842 T11843 compound BMP-6,protein
R9404 T11843 T11841 dobj protein,detected
R9405 T11697 T11693 prep in,production
R9406 T11844 T11843 prep in,protein
R9407 T11698 T11701 amod normal,cells
R9408 T11699 T11701 amod activated,cells
R9409 T11845 T11844 pobj humans,in
R9410 T11846 T11844 punct ",",in
R9411 T11700 T11701 compound B,cells
R9412 T11847 T11848 advmod especially,in
R9413 T11848 T11844 conj in,in
R9414 T11849 T11850 amod non-pathogenic,tissue
R9415 T11701 T11697 pobj cells,in
R9416 T11850 T11848 pobj tissue,in
R9417 T11851 T11841 punct .,detected
R9418 T11852 T11853 det The,possibility
R9419 T11853 T11860 nsubj possibility,is
R9420 T11854 T11853 prep of,possibility
R9421 T11702 T11703 auxpass was,detected
R9422 T11855 T11856 compound BMP-6,production
R9423 T11856 T11854 pobj production,of
R9424 T11703 T11703 ROOT detected,detected
R9425 T11857 T11856 prep in,production
R9426 T11858 T11859 amod human,B-cells
R9427 T11859 T11857 pobj B-cells,in
R9428 T11860 T11860 ROOT is,is
R9429 T11704 T11703 prep in,detected
R9430 T11861 T11860 prep in,is
R9431 T11862 T11861 pobj line,in
R9432 T11705 T11707 det the,study
R9433 T11863 T11862 prep with,line
R9434 T11864 T11866 det a,work
R9435 T11865 T11866 amod recent,work
R9436 T11866 T11863 pobj work,with
R9437 T11706 T11707 amod same,study
R9438 T11867 T11868 nsubj that,reported
R9439 T11868 T11866 relcl reported,work
R9440 T11707 T11704 pobj study,in
R9441 T11869 T11870 det the,production
R9442 T11870 T11868 dobj production,reported
R9443 T11871 T11870 prep of,production
R9444 T11872 T11871 pobj BMP-6,of
R9445 T11708 T11703 punct .,detected
R9446 T11873 T11870 prep in,production
R9447 T11874 T11876 compound mouse,cells
R9448 T11709 T11718 prep Of,reported
R9449 T11875 T11876 compound B,cells
R9450 T11876 T11873 pobj cells,in
R9451 T11877 T11860 punct ",",is
R9452 T11878 T11860 advcl infiltrating,is
R9453 T11710 T11709 pobj note,Of
R9454 T11879 T11881 det the,marrow
R9455 T11880 T11881 compound bone,marrow
R9456 T11881 T11878 dobj marrow,infiltrating
R9457 T11907 T11906 punct .,suggested
R9458 T11882 T11881 prep of,marrow
R9459 T11883 T11882 pobj mice,of
R9460 T11884 T11881 prep with,marrow
R9461 T11885 T11886 amod inflammatory,arthritis
R9462 T11886 T11884 pobj arthritis,with
R9463 T11908 T11909 det The,upregulation
R9464 T11887 T11889 nmod [,]
R9465 T11888 T11889 nummod 43,]
R9466 T11909 T11915 nsubj upregulation,is
R9467 T11889 T11881 appos ],marrow
R9468 T11890 T11860 punct .,is
R9469 T11891 T11906 prep In,suggested
R9470 T11892 T11893 det this,study
R9471 T11893 T11891 pobj study,In
R9472 T11894 T11906 punct ",",suggested
R9473 T11910 T11909 prep of,upregulation
R9474 T11895 T11896 det a,role
R9475 T11896 T11906 nsubjpass role,suggested
R9476 T11897 T11896 prep for,role
R9477 T11911 T11912 det the,BMP-6-transcripts
R9478 T11898 T11897 pobj BMPs,for
R9479 T11899 T11898 prep in,BMPs
R9480 T11900 T11902 det the,process
R9481 T11912 T11910 pobj BMP-6-transcripts,of
R9482 T11901 T11902 amod inflammatoric,process
R9483 T11902 T11899 pobj process,in
R9484 T11903 T11902 prep of,process
R9485 T11913 T11909 prep after,upregulation
R9486 T11904 T11903 pobj arthritis,of
R9487 T11905 T11906 auxpass was,suggested
R9488 T11906 T11906 ROOT suggested,suggested
R9489 T11914 T11915 nsubj IgM-crosslinking,is
R9490 T11915 T11915 ROOT is,is
R9491 T11916 T11915 prep of,is
R9492 T11917 T11918 amod pathophysiologic,interest
R9493 T11918 T11916 pobj interest,of
R9494 T12004 T12013 mark that,define
R9495 T11919 T11921 nmod [,]
R9496 T12005 T12006 amod cellular,context
R9497 T12006 T12013 nsubj context,define
R9498 T11920 T11921 nummod 12,]
R9499 T11921 T11915 attr ],is
R9500 T12007 T12006 prep of,context
R9501 T11922 T11915 punct .,is
R9502 T12008 T12011 det the,cell
R9503 T12009 T12011 compound BMP,cell
R9504 T11923 T11924 det A,loss
R9505 T12010 T12011 compound target,cell
R9506 T12011 T12007 pobj cell,of
R9507 T12012 T12013 aux might,define
R9508 T11924 T11929 nsubjpass loss,suggested
R9509 T12013 T12003 ccomp define,indicating
R9510 T12014 T12017 det the,effects
R9511 T11925 T11924 prep of,loss
R9512 T11926 T11925 pobj TGF-β-responsiveness,of
R9513 T12015 T12017 amod various,effects
R9514 T12016 T12017 amod observed,effects
R9515 T12017 T12013 dobj effects,define
R9516 T11927 T11929 aux has,suggested
R9517 T12018 T11982 punct .,are
R9518 T12019 T12032 prep In,were
R9519 T12020 T12019 pobj contrast,In
R9520 T12021 T12020 prep to,contrast
R9521 T12022 T12023 det the,upregulation
R9522 T11928 T11929 auxpass been,suggested
R9523 T12023 T12021 pobj upregulation,to
R9524 T12024 T12023 prep of,upregulation
R9525 T12025 T12026 compound BMP-6,transcript
R9526 T12026 T12024 pobj transcript,of
R9527 T12027 T12023 prep in,upregulation
R9528 T12028 T12029 compound B,cells
R9529 T11929 T11929 ROOT suggested,suggested
R9530 T12029 T12027 pobj cells,in
R9531 T12030 T12032 punct ",",were
R9532 T12031 T12032 nsubj we,were
R9533 T11930 T11931 aux to,be
R9534 T12032 T12032 ROOT were,were
R9535 T12033 T12032 neg not,were
R9536 T12034 T12032 acomp able,were
R9537 T11931 T11929 xcomp be,suggested
R9538 T12035 T12036 aux to,detect
R9539 T12036 T12034 xcomp detect,able
R9540 T11932 T11934 det a,contribution
R9541 T12037 T12038 compound BMP-6,transcripts
R9542 T12038 T12036 dobj transcripts,detect
R9543 T12039 T12036 prep in,detect
R9544 T11933 T11934 amod critical,contribution
R9545 T12040 T12042 amod human,blood
R9546 T12041 T12042 amod peripheral,blood
R9547 T12042 T12043 compound blood,CD4
R9548 T12043 T12039 pobj CD4,in
R9549 T11934 T11931 attr contribution,be
R9550 T12044 T12043 nummod +,CD4
R9551 T12045 T12043 cc or,CD4
R9552 T12046 T12049 nummod CD8,cells
R9553 T11935 T11934 prep to,contribution
R9554 T12047 T12049 nummod +,cells
R9555 T12048 T12049 compound T,cells
R9556 T12049 T12043 conj cells,CD4
R9557 T11936 T11937 amod malignant,transformation
R9558 T12050 T12051 punct (,resting
R9559 T12051 T12043 acl resting,CD4
R9560 T11937 T11935 pobj transformation,to
R9561 T12052 T12051 cc or,resting
R9562 T12053 T12051 conj stimulated,resting
R9563 T12054 T12053 prep with,stimulated
R9564 T11938 T11940 nmod [,]
R9565 T12055 T12059 amod anti-CD3,data
R9566 T12056 T12055 cc and,anti-CD3
R9567 T12057 T12055 conj anti-CD28,anti-CD3
R9568 T12058 T12059 punct ;,data
R9569 T12059 T12054 pobj data,with
R9570 T12060 T12061 neg not,shown
R9571 T11939 T11940 nummod "47,48",]
R9572 T12061 T12059 acl shown,data
R9573 T12062 T12059 punct ),data
R9574 T12063 T12059 punct ",",data
R9575 T12064 T12059 amod consistent,data
R9576 T11940 T11944 nmod ],mechanisms
R9577 T12065 T12064 prep with,consistent
R9578 T12066 T12067 det the,findings
R9579 T12067 T12065 pobj findings,with
R9580 T11941 T11940 cc and,]
R9581 T12068 T12067 prep in,findings
R9582 T12069 T12070 compound T,cell
R9583 T12070 T12071 compound cell,lines
R9584 T11942 T11944 amod similar,mechanisms
R9585 T12071 T12068 pobj lines,in
R9586 T12072 T12074 nmod [,]
R9587 T11943 T11944 amod oncogenic,mechanisms
R9588 T12073 T12074 nummod 20,]
R9589 T12074 T12077 nmod ],cells
R9590 T12075 T12074 cc and,]
R9591 T11944 T11947 nsubjpass mechanisms,postulated
R9592 T12076 T12074 conj T,]
R9593 T12077 T12067 conj cells,findings
R9594 T12078 T12067 prep in,findings
R9595 T11945 T11947 aux have,postulated
R9596 T12079 T12078 pobj mice,in
R9597 T12080 T12082 nmod [,]
R9598 T12081 T12082 nummod 43,]
R9599 T11946 T11947 auxpass been,postulated
R9600 T11947 T11929 conj postulated,suggested
R9601 T12082 T12067 appos ],findings
R9602 T12083 T12032 punct .,were
R9603 T11948 T11947 prep for,postulated
R9604 T12084 T12087 amod Other,sources
R9605 T12085 T12087 amod potential,sources
R9606 T11949 T11948 pobj BMPs,for
R9607 T11950 T11947 punct .,postulated
R9608 T11951 T11954 nsubj Lines,suggest
R9609 T12086 T12087 compound BMP-6,sources
R9610 T12087 T12095 nsubj sources,be
R9611 T11952 T11951 prep of,Lines
R9612 T12088 T12087 prep for,sources
R9613 T12089 T12091 amod mature,cells
R9614 T12090 T12091 compound B,cells
R9615 T11953 T11952 pobj evidence,of
R9616 T12091 T12088 pobj cells,for
R9617 T12092 T12091 prep in,cells
R9618 T12093 T12092 pobj vivo,in
R9619 T12094 T12095 aux might,be
R9620 T12095 T12095 ROOT be,be
R9621 T11954 T11954 ROOT suggest,suggest
R9622 T12096 T12097 amod other,cells
R9623 T12097 T12095 attr cells,be
R9624 T11955 T11957 nsubj [,]
R9625 T12098 T12097 prep of,cells
R9626 T12099 T12101 det the,system
R9627 T11956 T11957 nummod 49,]
R9628 T12100 T12101 amod immune,system
R9629 T12101 T12098 pobj system,of
R9630 T11957 T11954 dobj ],suggest
R9631 T11958 T11966 mark that,is
R9632 T12102 T12101 cc or,system
R9633 T12103 T12101 conj tissue,system
R9634 T12104 T12103 prep with,tissue
R9635 T11959 T11966 prep at,is
R9636 T12105 T12104 pobj contact,with
R9637 T12106 T12105 prep to,contact
R9638 T11960 T11961 amod early,stages
R9639 T12107 T12109 det the,system
R9640 T12108 T12109 amod hematopoietic,system
R9641 T11961 T11959 pobj stages,at
R9642 T12109 T12106 pobj system,to
R9643 T12110 T12095 punct .,be
R9644 T11962 T11961 prep of,stages
R9645 T11963 T11962 pobj carcinogenesis,of
R9646 T11964 T11966 punct ",",is
R9647 T11965 T11966 nsubj BMP-6,is
R9648 T12111 T12114 nummod One,source
R9649 T12112 T12113 advmod well,recognized
R9650 T12113 T12114 amod recognized,source
R9651 T11966 T11957 relcl is,]
R9652 T12114 T12118 nsubj source,is
R9653 T12115 T12114 prep for,source
R9654 T11967 T11966 neg not,is
R9655 T12116 T12117 compound BMP-6,production
R9656 T12117 T12115 pobj production,for
R9657 T12118 T12118 ROOT is,is
R9658 T11968 T11970 det a,promoter
R9659 T12119 T12121 det the,bone
R9660 T12120 T12121 amod human,bone
R9661 T11969 T11970 compound tumour,promoter
R9662 T12121 T12118 attr bone,is
R9663 T12122 T12121 cc and,bone
R9664 T12123 T12124 compound bone,marrow
R9665 T11970 T11966 attr promoter,is
R9666 T12124 T12125 compound marrow,stroma
R9667 T12125 T12121 conj stroma,bone
R9668 T12126 T12128 compound [,]
R9669 T12127 T12128 compound "51,8",]
R9670 T12128 T12121 appos ],bone
R9671 T11971 T11954 punct ",",suggest
R9672 T12129 T12118 punct .,is
R9673 T12130 T12133 advmod Furthermore,is
R9674 T12131 T12133 punct ",",is
R9675 T12132 T12133 nsubj it,is
R9676 T11972 T11954 cc but,suggest
R9677 T12133 T12133 ROOT is,is
R9678 T12134 T12133 acomp noteworthy,is
R9679 T11973 T11954 conj suppresses,suggest
R9680 T12135 T12145 mark that,express
R9681 T12136 T12138 amod human,vein
R9682 T12137 T12138 amod umbilical,vein
R9683 T11974 T11978 amod benign,outgrowth
R9684 T12138 T12140 nmod vein,cells
R9685 T12139 T12140 amod endothelial,cells
R9686 T12140 T12145 nsubj cells,express
R9687 T11975 T11974 cc and,benign
R9688 T12141 T12140 punct (,cells
R9689 T12142 T12140 appos HUVEC,cells
R9690 T12143 T12140 punct ),cells
R9691 T11976 T11974 conj malignant,benign
R9692 T12144 T12145 advmod highly,express
R9693 T12145 T12133 ccomp express,is
R9694 T12146 T12148 compound BMP-6,[
R9695 T11977 T11978 compound tumour,outgrowth
R9696 T12147 T12148 compound mRNA,[
R9697 T12148 T12145 dobj [,express
R9698 T11978 T11973 dobj outgrowth,suppresses
R9699 T12149 T12150 nummod 52,]
R9700 T12150 T12148 conj ],[
R9701 T12151 T12150 punct ",",]
R9702 T12152 T12150 cc and,]
R9703 T11979 T11954 punct .,suggest
R9704 T12153 T12154 amod vascular,endothelium
R9705 T12154 T12150 conj endothelium,]
R9706 T12155 T12157 aux has,reported
R9707 T11980 T11981 det These,findings
R9708 T12156 T12157 auxpass been,reported
R9709 T12157 T12145 conj reported,express
R9710 T11981 T11982 nsubj findings,are
R9711 T12158 T12159 aux to,produce
R9712 T12159 T12157 xcomp produce,reported
R9713 T12160 T12161 compound BMP-6,[
R9714 T11982 T11982 ROOT are,are
R9715 T12161 T12159 dobj [,produce
R9716 T12162 T12163 nummod 53,]
R9717 T11983 T11982 prep in,are
R9718 T11984 T11985 amod good,agreement
R9719 T12163 T12161 appos ],[
R9720 T11985 T11983 pobj agreement,in
R9721 T12164 T12133 punct .,is
R9722 T11986 T11985 prep with,agreement
R9723 T12165 T12166 det These,studies
R9724 T12166 T12168 nsubj studies,imply
R9725 T12167 T12168 aux might,imply
R9726 T11987 T11988 amod previous,findings
R9727 T12168 T12168 ROOT imply,imply
R9728 T12169 T12170 det a,role
R9729 T12170 T12168 dobj role,imply
R9730 T11988 T11986 pobj findings,with
R9731 T12171 T12170 prep for,role
R9732 T12172 T12171 pobj BMP-6,for
R9733 T11989 T11985 prep for,agreement
R9734 T12173 T12170 prep in,role
R9735 T12174 T12175 amod transendothelial,migration
R9736 T12175 T12173 pobj migration,in
R9737 T11990 T11993 amod other,members
R9738 T12176 T12175 prep of,migration
R9739 T12177 T12178 compound B,cells
R9740 T12178 T12176 pobj cells,of
R9741 T11991 T11993 compound TGF-β,members
R9742 T12179 T12168 punct .,imply
R9743 T12180 T12184 npadvmod BMP-6,demonstrated
R9744 T11992 T11993 compound family,members
R9745 T12181 T12184 nsubjpass mRNA,demonstrated
R9746 T12182 T12184 aux has,demonstrated
R9747 T12183 T12184 auxpass been,demonstrated
R9748 T12184 T12184 ROOT demonstrated,demonstrated
R9749 T11993 T11989 pobj members,for
R9750 T12185 T12184 prep in,demonstrated
R9751 T12186 T12189 compound murine,lines
R9752 T11994 T11993 punct ",",members
R9753 T12187 T12189 compound macrophage,lines
R9754 T12188 T12189 compound cell,lines
R9755 T12189 T12185 pobj lines,in
R9756 T11995 T11993 prep including,members
R9757 T12190 T12184 punct ",",demonstrated
R9758 T12191 T12184 cc but,demonstrated
R9759 T12192 T12193 neg not,in
R9760 T11996 T11995 pobj TGF-β1,including
R9761 T12193 T12184 conj in,demonstrated
R9762 T12194 T12193 pobj humans,in
R9763 T12195 T12197 nmod [,]
R9764 T11997 T11996 cc and,TGF-β1
R9765 T12196 T12197 nummod 54,]
R9766 T12197 T12193 conj ],in
R9767 T12198 T12184 punct .,demonstrated
R9768 T11998 T11999 compound BMP-4,[
R9769 T12199 T12216 prep In,described
R9770 T11999 T11996 conj [,TGF-β1
R9771 T12200 T12199 pobj accordance,In
R9772 T12201 T12200 prep with,accordance
R9773 T12000 T12001 nummod 50,]
R9774 T12202 T12203 det these,findings
R9775 T12203 T12201 pobj findings,with
R9776 T12001 T11996 conj ],TGF-β1
R9777 T12204 T12216 punct ",",described
R9778 T12205 T12208 amod other,lines
R9779 T12206 T12208 amod human,lines
R9780 T12002 T11982 punct ",",are
R9781 T12003 T11982 advcl indicating,are
R9782 T12207 T12208 compound cell,lines
R9783 T12208 T12216 nsubjpass lines,described
R9784 T12209 T12208 prep of,lines
R9786 T12210 T12209 pobj neutrophil,of
R9787 T12211 T12210 cc and,neutrophil
R9788 T12212 T12213 amod monocytic,origin
R9789 T12213 T12210 conj origin,neutrophil
R9790 T12214 T12216 aux have,described
R9791 T12215 T12216 auxpass been,described
R9792 T12216 T12216 ROOT described,described
R9793 T12217 T12218 aux to,be
R9794 T12218 T12216 xcomp be,described
R9795 T12219 T12218 acomp negative,be
R9796 T12220 T12218 prep for,be
R9797 T12221 T12223 det the,transcript
R9798 T12222 T12223 compound BMP-6,transcript
R9799 T12223 T12220 pobj transcript,for
R9800 T12224 T12226 quantmod [,]
R9801 T12225 T12226 nummod 20,]
R9802 T12226 T12218 npadvmod ],be
R9803 T12227 T12216 punct .,described
R9804 T12228 T12233 prep To,is
R9805 T12229 T12230 poss our,knowledge
R9806 T12230 T12228 pobj knowledge,To
R9807 T12231 T12233 punct ",",is
R9808 T12232 T12233 expl there,is
R9809 T12233 T12233 ROOT is,is
R9810 T12234 T12233 advmod currently,is
R9811 T12235 T12236 det no,report
R9812 T12236 T12233 attr report,is
R9813 T12237 T12236 prep about,report
R9814 T12238 T12239 compound BMP-6,production
R9815 T12239 T12237 pobj production,about
R9816 T12240 T12239 prep of,production
R9817 T12241 T12243 amod human,cells
R9818 T12242 T12243 amod dendritic,cells
R9819 T12243 T12240 pobj cells,of
R9820 T12244 T12233 punct .,is