Id |
Subject |
Object |
Predicate |
Lexical cue |
Negation |
T6683 |
42-56 |
Negative_regulation |
denotes |
null mutations |
|
T6684 |
70-77 |
Protein |
denotes |
Sharpin |
|
T6685 |
202-206 |
Negative_regulation |
denotes |
loss |
|
T6686 |
210-217 |
Protein |
denotes |
SHARPIN |
|
T6687 |
685-692 |
Protein |
denotes |
SHARPIN |
|
T6688 |
735-745 |
Negative_regulation |
denotes |
disruption |
|
T6689 |
1406-1410 |
Protein |
denotes |
TNFα |
|
T6690 |
1481-1489 |
Negative_regulation |
denotes |
deletion |
|
T6691 |
1493-1496 |
Protein |
denotes |
TNF |
|
T6692 |
1523-1533 |
Negative_regulation |
denotes |
deficiency |
|
T6693 |
1537-1544 |
Protein |
denotes |
SHARPIN |
|
T6694 |
2015-2020 |
Protein |
denotes |
HMGB1 |
|
T6695 |
2021-2031 |
Binding |
denotes |
recognized |
|
T6696 |
2035-2039 |
Protein |
denotes |
TLR2 |
|
T6697 |
2040-2041 |
Protein |
denotes |
4 |
|
T6698 |
2548-2555 |
Protein |
denotes |
IL12P35 |
|
T6699 |
2561-2568 |
Protein |
denotes |
IL12P40 |
|
T6700 |
2569-2578 |
Negative_regulation |
denotes |
deficient |
|
T6701 |
2569-2578 |
Negative_regulation |
denotes |
deficient |
|
T6702 |
2664-2668 |
Protein |
denotes |
IRF3 |
|
T6703 |
2930-2940 |
Positive_regulation |
denotes |
activation |
|
T6704 |
2930-2940 |
Positive_regulation |
denotes |
activation |
|
T6705 |
2930-2940 |
Positive_regulation |
denotes |
activation |
|
T6706 |
2930-2940 |
Positive_regulation |
denotes |
activation |
|
T6707 |
2944-2948 |
Protein |
denotes |
TBK1 |
|
T6708 |
2949-2953 |
Protein |
denotes |
IRF3 |
|
T6709 |
2955-2959 |
Protein |
denotes |
ERK1 |
|
T6710 |
2960-2961 |
Protein |
denotes |
2 |
|
T6711 |
2970-2977 |
Negative_regulation |
denotes |
was not |
true |
T6712 |
2970-2977 |
Negative_regulation |
denotes |
was not |
true |
T6713 |
2970-2977 |
Negative_regulation |
denotes |
was not |
true |
T6714 |
2970-2977 |
Negative_regulation |
denotes |
was not |
true |
T6715 |
3386-3393 |
Protein |
denotes |
SHARPIN |
|
T6716 |
3548-3551 |
Protein |
denotes |
A20 |
|
T6717 |
3556-3560 |
Protein |
denotes |
ITCH |
|
T6718 |
4151-4159 |
Negative_regulation |
denotes |
deletion |
|
T6719 |
4163-4170 |
Protein |
denotes |
Sharpin |
|
T6720 |
4228-4235 |
Protein |
denotes |
SHARPIN |
|
T6721 |
4295-4302 |
Negative_regulation |
denotes |
absence |
|
T6722 |
4306-4313 |
Protein |
denotes |
Sharpin |
|
T6723 |
4314-4324 |
Gene_expression |
denotes |
expression |
|
T6724 |
4666-4670 |
Protein |
denotes |
p100 |
|
T6725 |
4693-4696 |
Protein |
denotes |
p52 |
|
T6726 |
4722-4729 |
Protein |
denotes |
SHARPIN |
|
T6727 |
4730-4739 |
Negative_regulation |
denotes |
deficient |
|
T6728 |
4793-4796 |
Protein |
denotes |
p52 |
|
T6729 |
4797-4801 |
Protein |
denotes |
RELB |
|
T6730 |
4917-4924 |
Protein |
denotes |
Sharpin |
|
T6731 |
4925-4933 |
Negative_regulation |
denotes |
mutation |
|
T6732 |
5070-5076 |
Binding |
denotes |
engage |
|
T6733 |
5070-5076 |
Binding |
denotes |
engage |
|
T6734 |
5077-5081 |
Protein |
denotes |
TLR4 |
|
T6735 |
5086-5090 |
Protein |
denotes |
TLR3 |
|
T6736 |
5302-5309 |
Binding |
denotes |
engages |
|
T6737 |
5310-5314 |
Protein |
denotes |
TLR4 |
|
T6738 |
5327-5332 |
Protein |
denotes |
MYD88 |
|
T6739 |
5347-5351 |
Protein |
denotes |
TRIF |
|
T6740 |
5380-5384 |
Protein |
denotes |
TLR3 |
|
T6741 |
5385-5395 |
Positive_regulation |
denotes |
stimulated |
|
T6742 |
5422-5426 |
Protein |
denotes |
TRIF |
|
T6743 |
5518-5525 |
Protein |
denotes |
Sharpin |
|
T6744 |
5526-5534 |
Negative_regulation |
denotes |
mutation |
|
T6745 |
5626-5630 |
Protein |
denotes |
RIP1 |
|
T6746 |
5635-5640 |
Protein |
denotes |
TRAF6 |
|
T6747 |
5680-5687 |
Protein |
denotes |
SHARPIN |
|
T6748 |
5688-5697 |
Binding |
denotes |
interacts |
|
T6749 |
5703-5707 |
Protein |
denotes |
HOIP |
|
T6750 |
5727-5733 |
Positive_regulation |
denotes |
exerts |
|
T6751 |
5727-5733 |
Positive_regulation |
denotes |
exerts |
|
T6752 |
5738-5776 |
Ubiquitination |
denotes |
linear-ubiquitin-chain-ligase activity |
|
T6753 |
5738-5776 |
Ubiquitination |
denotes |
linear-ubiquitin-chain-ligase activity |
|
T6754 |
5804-5808 |
Protein |
denotes |
RIP1 |
|
T6755 |
5813-5817 |
Protein |
denotes |
NEMO |
|
T6756 |
5852-5856 |
Protein |
denotes |
TNFα |
|
T6757 |
5890-5897 |
Protein |
denotes |
Sharpin |
|
T6758 |
5898-5911 |
Negative_regulation |
denotes |
null mutation |
|
T6759 |
5912-5920 |
Negative_regulation |
denotes |
disrupts |
|
T6760 |
5912-5920 |
Negative_regulation |
denotes |
disrupts |
|
T6761 |
5966-5970 |
Protein |
denotes |
TNFα |
|
T6762 |
6134-6141 |
Protein |
denotes |
SHARPIN |
|
T6763 |
6255-6262 |
Protein |
denotes |
SHARPIN |
|
T6764 |
6384-6391 |
Protein |
denotes |
Sharpin |
|
T6765 |
6392-6401 |
Negative_regulation |
denotes |
deficient |
|
R5370 |
T6684 |
T6683 |
themeOf |
Sharpin,null mutations |
R5371 |
T6686 |
T6685 |
themeOf |
SHARPIN,loss |
R5372 |
T6687 |
T6688 |
themeOf |
SHARPIN,disruption |
R5373 |
T6691 |
T6690 |
themeOf |
TNF,deletion |
R5374 |
T6693 |
T6692 |
themeOf |
SHARPIN,deficiency |
R5375 |
T6694 |
T6695 |
themeOf |
HMGB1,recognized |
R5376 |
T6696 |
T6695 |
themeOf |
TLR2,recognized |
R5377 |
T6698 |
T6701 |
themeOf |
IL12P35,deficient |
R5378 |
T6699 |
T6700 |
themeOf |
IL12P40,deficient |
R5379 |
T6703 |
T6712 |
themeOf |
activation,was not |
R5380 |
T6704 |
T6714 |
themeOf |
activation,was not |
R5381 |
T6705 |
T6711 |
themeOf |
activation,was not |
R5382 |
T6706 |
T6713 |
themeOf |
activation,was not |
R5383 |
T6707 |
T6706 |
themeOf |
TBK1,activation |
R5384 |
T6708 |
T6705 |
themeOf |
IRF3,activation |
R5385 |
T6709 |
T6703 |
themeOf |
ERK1,activation |
R5386 |
T6710 |
T6704 |
themeOf |
2,activation |
R5387 |
T6719 |
T6718 |
themeOf |
Sharpin,deletion |
R5388 |
T6722 |
T6723 |
themeOf |
Sharpin,expression |
R5389 |
T6723 |
T6721 |
themeOf |
expression,absence |
R5390 |
T6726 |
T6727 |
themeOf |
SHARPIN,deficient |
R5391 |
T6730 |
T6731 |
themeOf |
Sharpin,mutation |
R5392 |
T6734 |
T6732 |
themeOf |
TLR4,engage |
R5393 |
T6735 |
T6733 |
themeOf |
TLR3,engage |
R5394 |
T6737 |
T6736 |
themeOf |
TLR4,engages |
R5395 |
T6740 |
T6741 |
themeOf |
TLR3,stimulated |
R5396 |
T6743 |
T6744 |
themeOf |
Sharpin,mutation |
R5397 |
T6747 |
T6748 |
themeOf |
SHARPIN,interacts |
R5398 |
T6747 |
T6752 |
causeOf |
SHARPIN,linear-ubiquitin-chain-ligase activity |
R5399 |
T6747 |
T6753 |
causeOf |
SHARPIN,linear-ubiquitin-chain-ligase activity |
R5400 |
T6749 |
T6748 |
themeOf |
HOIP,interacts |
R5401 |
T6752 |
T6751 |
themeOf |
linear-ubiquitin-chain-ligase activity,exerts |
R5402 |
T6752 |
T6759 |
themeOf |
linear-ubiquitin-chain-ligase activity,disrupts |
R5403 |
T6753 |
T6750 |
themeOf |
linear-ubiquitin-chain-ligase activity,exerts |
R5404 |
T6753 |
T6760 |
themeOf |
linear-ubiquitin-chain-ligase activity,disrupts |
R5405 |
T6754 |
T6752 |
themeOf |
RIP1,linear-ubiquitin-chain-ligase activity |
R5406 |
T6755 |
T6753 |
themeOf |
NEMO,linear-ubiquitin-chain-ligase activity |
R5407 |
T6757 |
T6758 |
themeOf |
Sharpin,null mutation |
R5408 |
T6758 |
T6759 |
causeOf |
null mutation,disrupts |
R5409 |
T6758 |
T6760 |
causeOf |
null mutation,disrupts |
R5410 |
T6764 |
T6765 |
themeOf |
Sharpin,deficient |