PMC:3148254 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue Negation Speculation
T81 0-27 Protein denotes HOIL-1L Interacting Protein
T82 29-33 Protein denotes HOIP
T83 52-56 Protein denotes CD40
T84 115-119 Protein denotes CD40
T85 264-274 Binding denotes engagement
T86 278-282 Protein denotes CD40
T87 290-296 Protein denotes ligand
T88 297-302 Protein denotes CD154
T89 412-416 Protein denotes CD40
T90 530-534 Protein denotes CD40
T91 535-545 Binding denotes engagement
T92 738-742 Protein denotes CD40
T93 986-991 Protein denotes TRAF2
T94 992-1000 Positive_regulation denotes mediates
T95 1001-1012 Binding denotes recruitment
T96 1016-1043 Protein denotes HOIL-1L-interacting protein
T97 1045-1049 Protein denotes HOIP
T98 1058-1076 Entity denotes cytoplasmic domain
T99 1080-1084 Protein denotes CD40
T100 1102-1106 Protein denotes HOIP
T101 1125-1129 Protein denotes CD40
T102 1174-1178 Protein denotes HOIP
T103 1182-1186 Protein denotes CD40
T104 1265-1274 Negative_regulation denotes deficient
T105 1278-1282 Protein denotes HOIP
T106 1302-1306 Protein denotes CD40
T107 1307-1314 Positive_regulation denotes induced
T108 1315-1327 Positive_regulation denotes upregulation
T109 1331-1335 Protein denotes CD80
T110 1405-1414 Negative_regulation denotes defective
T111 1418-1422 Protein denotes HOIP
T112 1423-1432 Negative_regulation denotes deficient
T113 1463-1467 Protein denotes CD40
T114 1613-1617 Protein denotes HOIP
T115 1618-1627 Negative_regulation denotes deficient
T116 1690-1701 Positive_regulation denotes Restoration
T117 1705-1709 Protein denotes HOIP
T118 1710-1720 Gene_expression denotes expression
T119 1801-1805 Protein denotes HOIP
T120 1832-1836 Protein denotes CD40
T1114 1870-1874 Protein denotes CD40
T1115 2082-2086 Protein denotes CD40
T1116 2158-2162 Protein denotes CD40
T1117 2164-2169 Protein denotes CD154
T1118 2174-2183 Gene_expression denotes expressed
T1119 2216-2220 Protein denotes CD40
T1120 2221-2231 Binding denotes engagement
T1121 2484-2488 Protein denotes CD40
T1122 2559-2577 Entity denotes cytoplasmic domain
T1123 2581-2585 Protein denotes CD40
T1124 2685-2696 Binding denotes recruitment
T1125 2803-2808 Protein denotes TRAF1
T1126 2810-2815 Protein denotes TRAF2
T1127 2817-2822 Protein denotes TRAF3
T1128 2828-2833 Protein denotes TRAF6
T1129 2908-2912 Protein denotes CD40
T1130 2982-2989 Binding denotes binding
T1131 2982-2989 Binding denotes binding
T1132 2982-2989 Binding denotes binding
T1133 2982-2989 Binding denotes binding
T1134 2997-3013 Entity denotes cytoplasmic tail
T1135 3017-3021 Protein denotes CD40
T1136 3256-3265 Binding denotes associate
T1137 3256-3265 Binding denotes associate
T1138 3256-3265 Binding denotes associate
T1139 3271-3275 Protein denotes CD40
T1140 3277-3282 Protein denotes TRAF3
T1141 3340-3345 Protein denotes TRAF2
T1142 3350-3355 Protein denotes TRAF6
T1143 3447-3474 Protein denotes HOIL-1L interacting protein
T1144 3476-3480 Protein denotes HOIP
T1145 3572-3581 Binding denotes recruited
T1146 3585-3589 Protein denotes CD40
T1147 3595-3600 Protein denotes TRAF2
T1148 3601-3610 Regulation denotes dependent
T1149 3618-3627 Positive_regulation denotes following
T1150 3628-3638 Binding denotes engagement
T1151 3642-3646 Protein denotes CD40
T1152 3726-3730 Protein denotes HOIP
T1153 3731-3751 Positive_regulation denotes functions downstream true
T1154 3755-3760 Protein denotes TRAF2
T1155 3768-3772 Protein denotes CD40
T1156 3800-3804 Protein denotes HOIP
T6574 3800-3804 Protein denotes HOIP
T6575 3808-3817 Positive_regulation denotes necessary
T1157 3954-3960 Negative_regulation denotes ablate
T1158 3961-3971 Gene_expression denotes expression
T1159 3975-3979 Protein denotes HOIP
T1160 4051-4055 Protein denotes CD40
T1161 4099-4103 Protein denotes CD40
T1162 4104-4111 Positive_regulation denotes induced
T1163 4112-4124 Positive_regulation denotes upregulation
T1164 4128-4132 Protein denotes CD80
T1165 4176-4185 Negative_regulation denotes defective
T1166 4189-4193 Protein denotes HOIP
T1167 4194-4203 Negative_regulation denotes deficient
T1168 4226-4230 Protein denotes CD40
T1169 4235-4239 Protein denotes IL-4
T1170 4434-4441 Negative_regulation denotes absence
T1171 4445-4449 Protein denotes HOIP
T1172 4474-4478 Protein denotes CD40
T1173 4584-4588 Protein denotes HOIP
T1174 4589-4598 Negative_regulation denotes deficient
T1175 4649-4660 Binding denotes association true
T6576 4649-4660 Binding denotes association
T1176 4698-4702 Protein denotes CD40
T1177 4723-4727 Protein denotes HOIP
T1178 4728-4737 Negative_regulation denotes deficient
T1179 4781-4785 Protein denotes HOIP
T1180 4884-4888 Protein denotes CD40
T1181 4889-4899 Binding denotes engagement
T2812 4925-4929 Protein denotes HOIP
T2813 4930-4939 Negative_regulation denotes deficient
T2814 4961-4971 Negative_regulation denotes disruption
T2815 4975-4980 Protein denotes Rnf31
T2816 5000-5004 Protein denotes HOIP
T2817 5049-5053 Protein denotes HOIP
T2818 5057-5066 Binding denotes recruited
T2819 5202-5213 Binding denotes interaction
T2820 5217-5221 Protein denotes CD40
T2821 5227-5231 Protein denotes HOIP
T2822 5326-5337 Binding denotes recruitment
T2823 5341-5345 Protein denotes HOIP
T2824 5349-5353 Protein denotes CD40
T2825 5358-5363 Protein denotes TRAF2
T2826 5364-5373 Regulation denotes dependent
T2827 5413-5417 Protein denotes HOIP
T2828 5445-5449 Protein denotes CD40
T2829 5519-5523 Protein denotes HOIP
T2830 5540-5544 Protein denotes CD40
T2831 5624-5628 Protein denotes HOIP
T2832 5632-5636 Protein denotes CD40
T2833 5687-5694 Negative_regulation denotes disrupt
T2834 5713-5717 Protein denotes HOIP
T2835 5822-5826 Protein denotes CD40
T2836 6033-6038 Protein denotes Rnf31
T2837 6058-6062 Protein denotes HOIP
T2838 6288-6297 Negative_regulation denotes disrupted
T2839 6298-6303 Protein denotes Rnf31
T2840 6367-6376 Negative_regulation denotes disrupted
T2841 6377-6382 Protein denotes Rnf31
T2842 6471-6486 Protein denotes Cre recombinase
T2843 6609-6614 Protein denotes Rnf31
T2844 6620-6629 Negative_regulation denotes disrupted
T2845 6699-6703 Protein denotes HOIP
T2846 6712-6722 Gene_expression denotes expression true true
T2847 6961-6965 Protein denotes HOIP
T2848 6966-6975 Negative_regulation denotes deficient
T14778 7027-7031 Protein denotes HOIP
T14779 7063-7068 Protein denotes Rnf31
T14780 7104-7108 Protein denotes HOIP
T14781 7345-7350 Protein denotes Rnf31
T14782 7481-7485 Protein denotes HOIP
T14783 7918-7922 Protein denotes HOIP
T14784 7923-7932 Negative_regulation denotes deficient
T14785 7934-7938 Protein denotes HOIP
T14786 7961-7969 Negative_regulation denotes decrease
T14787 7973-7977 Protein denotes HOIP
T14788 7986-7996 Gene_expression denotes expression
T14789 8017-8026 Positive_regulation denotes following
T14790 8027-8037 Negative_regulation denotes disruption
T14791 8053-8058 Protein denotes Rnf31
T14792 8060-8064 Protein denotes HOIP
T14793 8070-8074 Protein denotes HOIP
T14794 8075-8085 Gene_expression denotes expression
T14795 8193-8197 Protein denotes HOIP
T14796 8245-8249 Protein denotes HOIP
T2849 8340-8344 Protein denotes HOIP
T2850 8345-8354 Negative_regulation denotes deficient
T2851 8373-8383 Negative_regulation denotes disruption
T2852 8391-8396 Protein denotes Rnf31
T2853 8408-8412 Protein denotes HOIP
T2854 8413-8422 Negative_regulation denotes deficient
T2855 8499-8503 Protein denotes HOIP
T2856 8510-8519 Positive_regulation denotes restoring
T2857 8520-8524 Protein denotes HOIP
T2858 8533-8543 Gene_expression denotes expression
T2859 8586-8590 Protein denotes HOIP
T2860 8591-8604 Positive_regulation denotes reconstituted
T2861 8712-8716 Protein denotes HOIP
T2862 8717-8726 Negative_regulation denotes deficient
T4174 8815-8819 Protein denotes HOIP
T4175 8823-8831 Positive_regulation denotes required
T4176 8823-8831 Positive_regulation denotes required
T4177 8836-8840 Protein denotes CD40
T4178 8841-8849 Positive_regulation denotes mediated
T4179 8841-8849 Positive_regulation denotes mediated
T4180 8850-8854 Protein denotes CD80
T4181 8855-8867 Positive_regulation denotes upregulation
T4182 8872-8882 Positive_regulation denotes activation
T4183 8886-8902 Protein denotes germline epsilon
T4184 8903-8916 Transcription denotes transcription
T4185 8917-8927 Binding denotes Engagement
T4186 8931-8935 Protein denotes CD40
T4187 8947-8958 Positive_regulation denotes upregulates
T4188 8959-8969 Gene_expression denotes expression
T4189 8973-8977 Protein denotes CD80
T4190 9130-9134 Protein denotes HOIP
T4191 9138-9142 Protein denotes CD40
T4192 9169-9181 Positive_regulation denotes upregulation
T4193 9185-9189 Protein denotes CD80
T4194 9190-9197 Positive_regulation denotes induced true
T4195 9201-9211 Binding denotes engagement
T4196 9215-9219 Protein denotes CD40
T4197 9240-9244 Protein denotes HOIP
T4198 9260-9264 Protein denotes HOIP
T4199 9265-9278 Positive_regulation denotes reconstituted
T4200 9335-9339 Protein denotes CD40
T4201 9340-9350 Positive_regulation denotes stimulated
T4202 9351-9363 Positive_regulation denotes upregulation
T4203 9367-9371 Protein denotes CD80
T4204 9389-9396 Negative_regulation denotes reduced
T4205 9404-9408 Protein denotes HOIP
T4206 9409-9418 Negative_regulation denotes deficient
T4207 9446-9458 Positive_regulation denotes upregulation
T4208 9462-9466 Protein denotes CD80
T4209 9483-9487 Protein denotes HOIP
T4210 9488-9501 Positive_regulation denotes reconstituted
T4211 9529-9535 Negative_regulation denotes defect
T4212 9539-9543 Protein denotes CD80
T4213 9544-9556 Positive_regulation denotes upregulation
T4214 9564-9568 Protein denotes HOIP
T4215 9569-9578 Negative_regulation denotes deficient
T4216 9589-9592 Positive_regulation denotes due
T4217 9600-9610 Negative_regulation denotes disruption
T4218 9614-9619 Protein denotes Rnf31
T15371 9665-9669 Protein denotes CD40
T15372 9670-9678 Positive_regulation denotes mediated
T15373 9679-9683 Protein denotes CD80
T15374 9684-9696 Positive_regulation denotes upregulation
T15375 9700-9709 Negative_regulation denotes defective
T15376 9713-9717 Protein denotes HOIP
T15377 9718-9727 Negative_regulation denotes deficient
T15378 9858-9868 Gene_expression denotes expression true
T15379 9872-9876 Protein denotes CD80
T15380 10020-10024 Protein denotes HOIP
T15381 10025-10034 Negative_regulation denotes deficient
T15382 10036-10040 Protein denotes HOIP
T15383 10084-10088 Protein denotes HOIP
T15384 10089-10097 Negative_regulation denotes reversed
T15385 10098-10107 Negative_regulation denotes defective
T15386 10108-10112 Protein denotes CD80
T15387 10113-10125 Positive_regulation denotes upregulation
T4219 10239-10243 Protein denotes CD40
T4220 10664-10668 Protein denotes IL-4
T4221 10673-10677 Protein denotes CD40
T4222 10879-10883 Protein denotes HOIP
T4223 10996-11000 Protein denotes CD40
T4224 11020-11024 Protein denotes IL-4
T4225 11040-11050 Transcription denotes production true
T4226 11054-11070 Protein denotes germline epsilon
T4227 11072-11075 Protein denotes GLε
T4228 11153-11157 Protein denotes IL-4
T4229 11158-11165 Positive_regulation denotes induced
T4230 11166-11169 Protein denotes GLε
T4231 11170-11183 Transcription denotes transcription
T4232 11254-11257 Protein denotes GLε
T4233 11258-11268 Gene_expression denotes expression
T4234 11286-11290 Protein denotes HOIP
T4235 11291-11300 Negative_regulation denotes deficient
T4236 11372-11376 Protein denotes IL-4
T4237 11395-11398 Protein denotes GLε
T4238 11399-11409 Gene_expression denotes expression
T4239 11415-11422 Positive_regulation denotes induced
T4240 11426-11430 Protein denotes HOIP
T4241 11431-11444 Positive_regulation denotes reconstituted
T4242 11509-11513 Protein denotes IL-4
T4243 11557-11561 Protein denotes HOIP
T4244 11607-11611 Protein denotes CD40
T15715 11667-11670 Protein denotes GLε
T15716 11671-11684 Transcription denotes transcription
T15717 11688-11697 Negative_regulation denotes defective
T15718 11701-11705 Protein denotes CD40
T15719 11717-11721 Protein denotes HOIP
T15720 11722-11731 Negative_regulation denotes deficient
T15721 11750-11754 Protein denotes HOIP
T15722 11755-11764 Negative_regulation denotes deficient
T15723 11833-11837 Protein denotes HOIP
T15724 11867-11871 Protein denotes HOIP
T15725 11872-11881 Negative_regulation denotes deficient
T15726 11906-11910 Protein denotes HOIP
T15727 11932-11936 Protein denotes HOIP
T15728 11942-11946 Protein denotes HOIP
T15729 12051-12055 Protein denotes IL-4
T15730 12173-12176 Protein denotes GLε
T15731 12177-12188 Transcription denotes transcripts true
T15732 12231-12236 Protein denotes Hprt1
T15733 12237-12248 Transcription denotes transcripts
T15734 12463-12467 Protein denotes HOIP
T15735 12468-12477 Negative_regulation denotes deficient
T5461 12486-12490 Protein denotes HOIP
T5462 12500-12504 Protein denotes CD40
T5463 12579-12583 Protein denotes HOIP
T5464 12611-12615 Protein denotes CD40
T5465 12672-12676 Protein denotes HOIP
T5466 12705-12709 Protein denotes CD40
T5467 12797-12802 Protein denotes CD154
T5468 12804-12815 Protein denotes CD40 ligand
T5469 12817-12826 Gene_expression denotes expressed
T5470 12968-12972 Protein denotes CD40
T5471 12983-12993 Binding denotes associated
T5472 12994-12999 Protein denotes CD154
T5473 13334-13345 Regulation denotes responsible
T5474 13350-13362 Negative_regulation denotes sequestering
T5475 13363-13377 Protein denotes NF-κB subunits
T5476 13554-13558 Protein denotes CD40
T5477 13559-13567 Positive_regulation denotes mediated
T5478 13559-13567 Positive_regulation denotes mediated
T5479 13568-13583 Phosphorylation denotes phosphorylation
T5480 13588-13599 Protein_catabolism denotes degradation
T5481 13603-13607 Protein denotes IκBα
T5482 13611-13615 Protein denotes HOIP
T5483 13616-13625 Negative_regulation denotes deficient
T5484 13649-13657 Negative_regulation denotes impaired
T5485 13649-13657 Negative_regulation denotes impaired
T5486 13804-13808 Protein denotes CD40
T5487 13809-13819 Binding denotes engagement
T5488 13830-13834 Protein denotes CD40
T5489 13862-13866 Protein denotes HOIP
T5490 13867-13876 Negative_regulation denotes deficient
T5491 13956-13960 Protein denotes CD40
T5492 14000-14004 Protein denotes HOIP
T5493 14005-14018 Positive_regulation denotes reconstituted
T5494 14128-14132 Protein denotes HOIP
T5495 14133-14143 Gene_expression denotes expression true
T16162 14189-14193 Protein denotes CD40
T16163 14246-14250 Protein denotes HOIP
T16164 14251-14260 Negative_regulation denotes deficient
T16165 14268-14272 Protein denotes CD40
T16166 14309-14313 Protein denotes HOIP
T16167 14314-14323 Negative_regulation denotes deficient
T16168 14443-14447 Protein denotes HOIP
T16169 14448-14457 Negative_regulation denotes deficient
T16170 14509-14513 Protein denotes HOIP
T16171 14515-14519 Protein denotes HOIP
T16172 14525-14529 Protein denotes HOIP
T16173 14558-14563 Protein denotes CD154
T16174 14564-14574 Gene_expression denotes expressing
T16175 14676-14683 Negative_regulation denotes lacking
T16176 14684-14689 Protein denotes CD154
T16177 14797-14809 Protein denotes Phospho-IκBα
T16178 14811-14816 Protein denotes pIκBα
T16179 14884-14888 Protein denotes IκBα
T16180 14971-14975 Protein denotes IκBα
T16181 15189-15193 Protein denotes HOIP
T16182 15194-15203 Negative_regulation denotes deficient
T6577 15270-15274 Protein denotes CD40
T6578 15297-15301 Protein denotes CD40
T6579 15354-15358 Protein denotes HOIP
T6580 15359-15368 Negative_regulation denotes deficient
T6581 15390-15394 Protein denotes HOIP
T6582 15521-15525 Protein denotes HOIP
T6583 15529-15538 Binding denotes recruited
T6584 15574-15579 Protein denotes TRAF2
T6585 15580-15589 Regulation denotes dependent
T6586 15614-15618 Protein denotes HOIP
T6587 15619-15639 Regulation denotes functions downstream true
T6588 15643-15648 Protein denotes TRAF2
T6589 15689-15694 Protein denotes TRAF2
T6590 15695-15705 Binding denotes associated
T6591 15695-15705 Binding denotes associated
T6592 15715-15720 Protein denotes cIAP1
T6593 15725-15730 Protein denotes cIAP2
T6594 15738-15742 Regulation denotes role
T6595 15738-15742 Regulation denotes role
T6596 15738-15742 Regulation denotes role
T6597 15738-15742 Regulation denotes role
T6598 15750-15761 Binding denotes recruitment
T6599 15750-15761 Binding denotes recruitment
T6600 15765-15769 Protein denotes HOIP
T6601 15773-15778 Protein denotes TNFR1
T6602 15783-15787 Protein denotes CD40
T6603 15831-15842 Binding denotes association
T6604 15846-15850 Protein denotes HOIP
T6605 15856-15860 Protein denotes CD40
T6606 15881-15888 Regulation denotes altered true
T6607 16095-16102 Negative_regulation denotes reduced
T6608 16117-16122 Protein denotes cIAP1
T6609 16123-16133 Binding denotes associated
T6610 16262-16270 Positive_regulation denotes resulted
T6611 16262-16270 Positive_regulation denotes resulted
T6612 16300-16308 Negative_regulation denotes decrease
T6613 16336-16340 Protein denotes HOIP
T6614 16346-16355 Binding denotes recovered
T6615 16359-16363 Protein denotes CD40
T6616 16408-16416 Positive_regulation denotes increase
T6617 16452-16462 Binding denotes recognized
T6618 16539-16544 Regulation denotes alter true
T6619 16579-16583 Protein denotes HOIP
T6620 16669-16675 Regulation denotes alters
T6621 16699-16703 Protein denotes CD40
T6622 16704-16714 Binding denotes associated
T6623 16715-16719 Protein denotes HOIP
T6624 16824-16828 Protein denotes cIAP
T6625 16838-16847 Regulation denotes influence
T6626 16838-16847 Regulation denotes influence
T6627 16852-16863 Binding denotes recruitment
T6628 16868-16899 Protein_modification denotes post-translational modification
T6629 16909-16913 Protein denotes CD40
T6630 16914-16924 Binding denotes associated
T6631 16925-16929 Protein denotes HOIP
T16768 17037-17041 Protein denotes HOIP
T16769 17042-17051 Negative_regulation denotes deficient
T16770 17086-17093 Negative_regulation denotes reduces
T16771 17094-17105 Binding denotes recruitment
T16772 17109-17114 Protein denotes cIAP1
T16773 17118-17122 Protein denotes CD40
T16774 17131-17137 Regulation denotes modify true
T16775 17138-17142 Protein denotes HOIP
T16776 17143-17154 Binding denotes recruitment
T16777 17749-17754 Protein denotes cIAP1
T16778 17756-17761 Protein denotes TRAF2
T16779 17763-17768 Protein denotes TRAF3
T16780 17774-17778 Protein denotes HOIP
T16781 17895-17899 Protein denotes CD40
T16782 17970-17974 Protein denotes HOIP
T16783 17975-17984 Negative_regulation denotes deficient
T16784 18073-18077 Protein denotes HOIP
T16785 18209-18213 Protein denotes CD40
T16786 18215-18220 Protein denotes TRAF2
T16787 18222-18227 Protein denotes TRAF3
T16788 18229-18234 Protein denotes cIAP1
T16789 18236-18240 Protein denotes HOIP
T16790 18242-18246 Protein denotes IKKα
T16791 18247-18248 Protein denotes β
T16792 18254-18258 Protein denotes IKKγ
T16793 18275-18279 Protein denotes HOIP
T16794 18280-18290 Gene_expression denotes expression
T16795 18345-18349 Protein denotes CD40
T16796 18508-18512 Protein denotes HOIP
T16797 18513-18522 Negative_regulation denotes deficient
T16798 18554-18558 Protein denotes HOIP
T16799 18559-18568 Regulation denotes dependent true
T16800 18569-18580 Binding denotes recruitment
T16801 18584-18588 Protein denotes IKKγ
T16802 18592-18596 Protein denotes CD40
T16803 18614-18618 Protein denotes HOIP
T16804 18619-18628 Negative_regulation denotes deficient
T16805 18630-18634 Protein denotes HOIP
T16806 18753-18757 Protein denotes IKKγ
T16807 18782-18786 Protein denotes pMIP
T16808 18791-18795 Protein denotes IKKγ
T16809 18997-19001 Protein denotes IKKγ
T16810 19020-19025 Protein denotes TRAF2
T16811 19285-19290 Protein denotes TRAF3
T16812 19295-19299 Protein denotes HOIP
T6632 19413-19417 Protein denotes HOIP
T6633 19421-19432 Regulation denotes responsible true
T6634 19441-19452 Binding denotes recruitment
T6635 19493-19497 Protein denotes CD40
T6636 19551-19555 Protein denotes HOIP
T6637 19556-19565 Negative_regulation denotes deficient
T6638 19570-19574 Protein denotes HOIP
T6639 19575-19588 Positive_regulation denotes reconstituted
T6640 19703-19707 Protein denotes HOIP
T6641 19719-19724 Protein denotes TRAF2
T6642 19726-19731 Protein denotes TRAF3
T6643 19733-19737 Protein denotes IKKα
T6644 19738-19739 Protein denotes β
T6645 19745-19749 Protein denotes IKKγ
T6646 19770-19775 Protein denotes TRAF2
T6647 19777-19782 Protein denotes TRAF3
T6648 19788-19793 Protein denotes cIAP1
T6649 19797-19801 Protein denotes CD40
T6650 19826-19830 Protein denotes HOIP
T6651 19913-19917 Protein denotes HOIP
T6652 19925-19933 Positive_regulation denotes required true
T6653 19925-19933 Positive_regulation denotes required true
T6654 19925-19933 Positive_regulation denotes required true
T6655 19942-19953 Binding denotes association
T6656 19942-19953 Binding denotes association
T6657 19942-19953 Binding denotes association
T6658 19977-19981 Protein denotes CD40
T6659 19996-20000 Protein denotes IKKα
T6660 20001-20002 Protein denotes β
T6661 20007-20011 Protein denotes IKKγ
T6662 20035-20039 Protein denotes CD40
T6663 20074-20078 Protein denotes HOIP
T6664 20079-20088 Negative_regulation denotes deficient
T6665 20123-20127 Protein denotes IKKα
T6666 20128-20129 Protein denotes β
T6667 20134-20138 Protein denotes IKKγ
T6668 20142-20146 Protein denotes CD40
T6669 20171-20175 Protein denotes HOIP
T6670 20176-20189 Positive_regulation denotes reconstituted
T6671 20359-20366 Negative_regulation denotes absence
T6672 20370-20374 Protein denotes HOIP
T6673 20375-20385 Gene_expression denotes expression
T6674 20412-20416 Protein denotes HOIP
T6675 20553-20557 Protein denotes IKKγ
T6676 20569-20573 Protein denotes CD40
T6677 20732-20736 Protein denotes IKKγ
T6678 20866-20870 Protein denotes IKKγ
T6679 20889-20893 Protein denotes CD40
T6680 21131-21135 Protein denotes IKKγ
T6681 21200-21210 Gene_expression denotes expressing
T6682 21226-21230 Protein denotes IKKγ
T6683 21246-21257 Binding denotes recruitment
T6684 21261-21265 Protein denotes IKKγ
T6685 21269-21273 Protein denotes CD40
T6686 21274-21282 Positive_regulation denotes requires
T6687 21283-21287 Protein denotes HOIP
T6688 21361-21365 Protein denotes IKKγ
T6689 21369-21373 Protein denotes CD40
T6690 21575-21579 Protein denotes CD40
T6691 21580-21590 Binding denotes associated
T6692 21591-21595 Protein denotes IKKγ
T6693 21808-21812 Protein denotes CD40
T6694 21813-21823 Binding denotes associated
T6695 21824-21828 Protein denotes IKKγ
T6696 21890-21905 Phosphorylation denotes phosphorylation
T6697 21944-21948 Protein denotes HOIP
T6698 21952-21960 Positive_regulation denotes required
T6699 21969-21980 Binding denotes association
T6700 21984-21988 Protein denotes IKKγ
T6701 21994-21998 Protein denotes CD40
T6702 22031-22038 Positive_regulation denotes coupled
T6703 22042-22074 Protein_modification denotes post-translational modifications
T6704 22078-22082 Protein denotes IKKγ
T9062 22134-22138 Protein denotes HOIP
T9063 22155-22159 Protein denotes CD40
T9064 22226-22230 Protein denotes HOIP
T9065 22231-22240 Regulation denotes dependent
T9066 22268-22272 Protein denotes CD40
T9067 22273-22281 Positive_regulation denotes mediated
T9068 22282-22294 Positive_regulation denotes upregulation
T9069 22298-22302 Protein denotes CD80
T9070 22303-22313 Gene_expression denotes expression
T9071 22533-22537 Protein denotes HOIP
T9072 22548-22558 Regulation denotes downstream
T9073 22562-22567 Protein denotes TRAF2
T9074 22575-22579 Protein denotes CD40
T9075 22607-22611 Protein denotes HOIP
T9076 22622-22626 Regulation denotes role
T9077 22630-22639 Positive_regulation denotes promoting
T9078 22644-22655 Binding denotes recruitment
T9079 22678-22682 Protein denotes CD40
T9080 22706-22710 Protein denotes CD40
T9081 22809-22813 Protein denotes HOIP
T9082 22863-22867 Protein denotes CD40
T9083 22868-22878 Binding denotes engagement
T9084 22943-22947 Protein denotes HOIP
T9085 22974-22978 Protein denotes CD40
T9086 23022-23026 Protein denotes CD40
T9087 23110-23114 Protein denotes HOIP
T9088 23204-23208 Protein denotes HOIP
T9089 23277-23281 Protein denotes HOIP
T9090 23306-23312 Protein denotes HOIL-1
T9091 23484-23492 Binding denotes interact
T9092 23498-23502 Protein denotes IKKγ
T9093 23652-23660 Positive_regulation denotes mediates
T9094 23661-23672 Binding denotes recruitment
T9095 23676-23680 Protein denotes IKKγ
T9096 23725-23729 Protein denotes CD40
T9097 23730-23740 Binding denotes associated
T9098 23741-23745 Protein denotes HOIP
T9099 23759-23763 Regulation denotes role
T9100 23767-23777 Positive_regulation denotes activating
T9101 23778-23782 Protein denotes IKKγ
T9102 23793-23804 Binding denotes recruitment
T9103 23873-23877 Protein denotes IKKγ
T9104 23893-23897 Protein denotes CD40
T9105 24003-24018 Phosphorylation denotes phosphorylation true
T9106 24023-24037 Ubiquitination denotes ubiquitination true
T9107 24068-24074 Negative_regulation denotes reduce
T9108 24068-24074 Negative_regulation denotes reduce
T9109 24078-24085 Positive_regulation denotes enhance
T9110 24078-24085 Positive_regulation denotes enhance
T9111 24086-24090 Protein denotes IKKγ
T9112 24150-24154 Protein denotes HOIP
T9113 24155-24163 Positive_regulation denotes mediates
T9114 24164-24175 Binding denotes recruitment
T9115 24198-24202 Protein denotes CD40
T9116 24216-24220 Protein denotes HOIP
T9117 24224-24233 Binding denotes recruited
T9118 24237-24241 Protein denotes CD40
T9119 24290-24294 Protein denotes HOIP
T9120 24369-24392 Positive_regulation denotes functions as an adaptor
T9121 24401-24412 Binding denotes recruitment
T9122 24435-24439 Protein denotes CD40
T9123 24483-24487 Protein denotes HOIP
T9124 24548-24552 Protein denotes IKKγ
T9125 24572-24579 Binding denotes binding true
T9126 24633-24637 Protein denotes HOIP
T9127 24744-24749 Positive_regulation denotes serve
T9128 24753-24760 Binding denotes recruit
T9129 24761-24765 Protein denotes IKKγ
T9130 24824-24833 Positive_regulation denotes necessary
T9131 24838-24849 Binding denotes recruitment
T9132 24853-24857 Protein denotes HOIP
T9133 24964-24975 Binding denotes recruitment
T9134 24979-24983 Protein denotes HOIP
T9135 25012-25017 Protein denotes TRAF2
T9136 25018-25027 Regulation denotes dependent
T9137 25046-25051 Protein denotes TRAF2
T9138 25056-25060 Protein denotes HOIP
T9139 25070-25078 Binding denotes interact
T9140 25137-25142 Protein denotes TRAF2
T9141 25254-25258 Protein denotes HOIP
T9142 25263-25267 Binding denotes bind
T9143 25277-25286 Binding denotes associate
T9144 25396-25401 Protein denotes TRAF2
T9145 25406-25410 Protein denotes HOIP
T9146 25414-25418 Protein denotes CD40
T9147 25487-25492 Protein denotes TRAF6
T9148 25504-25509 Protein denotes TRAF2
T9149 25610-25614 Protein denotes CD40
T9150 25643-25648 Protein denotes TRAF2
T9151 25652-25657 Protein denotes TRAF6
T9152 25686-25690 Protein denotes CD40
T9153 25716-25721 Protein denotes TRAF6
T9154 25733-25737 Protein denotes HOIP
T9155 25738-25748 Negative_regulation denotes deficiency
T9156 25765-25769 Protein denotes CD40
T9157 25854-25859 Protein denotes TRAF2
T9158 25864-25869 Protein denotes TRAF6
T9159 25890-25894 Protein denotes HOIP
T9160 25941-25945 Protein denotes CD40
T9161 25990-25995 Protein denotes TRAF6
T9162 26034-26044 Negative_regulation denotes disruption
T9163 26052-26064 Entity denotes binding site
T9164 26069-26074 Protein denotes TRAF6
T9165 26104-26108 Protein denotes CD40
T9166 26112-26120 Negative_regulation denotes deletion
T9167 26128-26151 Entity denotes receptor binding domain
T9168 26175-26180 Protein denotes TRAF6
T9169 26219-26224 Protein denotes TRAF6
T9170 26243-26247 Binding denotes bind
T9171 26248-26252 Protein denotes CD40
T9172 26436-26443 Negative_regulation denotes absence
T9173 26447-26451 Protein denotes HOIP
T9174 26535-26539 Protein denotes CD40
T9175 26619-26623 Protein denotes HOIP
T9176 26673-26678 Protein denotes TRAF2
T9177 26682-26687 Protein denotes TRAF6
T9178 26839-26843 Protein denotes HOIP
T9179 26939-26943 Protein denotes HOIP
T9180 26944-26953 Binding denotes interacts
T9181 26978-26985 Protein denotes SHARPIN
T9182 26987-27057 Protein denotes SHANK-associated RH domain interacting protein in postsynaptic density
T9183 27107-27111 Protein denotes HOIP
T9184 27116-27120 Protein denotes HOIL
T9185 27256-27263 Protein denotes SHARPIN
T9186 27538-27542 Binding denotes link
T9187 27551-27558 Protein denotes SHARPIN
T9188 27563-27567 Protein denotes HOIP
T9189 27638-27645 Negative_regulation denotes defects true
T9190 27653-27663 Regulation denotes regulation
T9191 27679-27683 Protein denotes HOIP
T11918 27909-27919 Gene_expression denotes expressing
T11919 27920-27925 Protein denotes CD154
T12312 28616-28620 Protein denotes HOIP
T12313 28621-28630 Negative_regulation denotes deficient
T12314 28739-28744 Protein denotes Rnf31
T12315 29746-29751 Protein denotes Rnf31
T12316 29761-29770 Negative_regulation denotes disrupted
T12317 29970-29975 Protein denotes Rnf31
T12318 30051-30055 Protein denotes HOIP
T12319 30064-30074 Gene_expression denotes expression true
T12894 30195-30199 Protein denotes HOIP
T12895 30204-30208 Protein denotes IKKγ
T12896 30399-30403 Protein denotes HOIP
T12897 30494-30498 Protein denotes IKKγ
T12898 30665-30669 Protein denotes HOIP
T12899 30679-30683 Protein denotes IKKγ
T12900 30812-30816 Protein denotes HOIP
T12901 30817-30826 Negative_regulation denotes deficient
T13341 31138-31142 Protein denotes CD80
T13342 31143-31155 Positive_regulation denotes upregulation
T13550 31544-31547 Protein denotes GLε
T13551 31569-31573 Protein denotes CD40
T13552 31574-31583 Positive_regulation denotes simulated true
T13553 31584-31594 Positive_regulation denotes activation
T13554 31598-31601 Protein denotes GLε
T13555 31602-31615 Transcription denotes transcription
T13556 31804-31808 Protein denotes IL-4
T13557 31951-31954 Protein denotes GLε
T13558 31959-31964 Protein denotes Hprt1
T13559 32093-32103 Gene_expression denotes Expression
T13560 32107-32110 Protein denotes GLε
T13561 32148-32158 Gene_expression denotes expression
T13562 32162-32167 Protein denotes Hprt1
T13864 32220-32224 Protein denotes CD40
T13865 32279-32289 Gene_expression denotes expressing
T13866 32296-32301 Protein denotes CD154
T13867 32303-32314 Protein denotes CD40 ligand
T14274 33136-33140 Protein denotes CD40
R10096 T12900 T12901 themeOf HOIP,deficient
R10479 T13341 T13342 themeOf CD80,upregulation
R10647 T13551 T13552 causeOf CD40,simulated
R10648 T13553 T13552 themeOf activation,simulated
R10649 T13554 T13555 themeOf GLε,transcription
R10650 T13555 T13553 themeOf transcription,activation
R10651 T13560 T13559 themeOf GLε,Expression
R10652 T13562 T13561 themeOf Hprt1,expression
R10898 T13866 T13865 themeOf CD154,expressing
R10899 T13867 T13866 equivalentTo CD40 ligand,CD154
R11696 T14783 T14784 themeOf HOIP,deficient
R11697 T14786 T14789 themeOf decrease,following
R11698 T14787 T14788 themeOf HOIP,expression
R11699 T14788 T14786 themeOf expression,decrease
R11700 T14790 T14789 causeOf disruption,following
R11701 T14791 T14790 themeOf Rnf31,disruption
R11702 T14793 T14794 themeOf HOIP,expression
R12170 T15371 T15372 causeOf CD40,mediated
R12171 T15372 T15375 themeOf mediated,defective
R12172 T15373 T15374 themeOf CD80,upregulation
R12173 T15374 T15372 themeOf upregulation,mediated
R12174 T15376 T15377 themeOf HOIP,deficient
R12175 T15379 T15378 themeOf CD80,expression
R12176 T15380 T15381 themeOf HOIP,deficient
R12177 T15385 T15384 themeOf defective,reversed
R12178 T15386 T15387 themeOf CD80,upregulation
R12179 T15387 T15385 themeOf upregulation,defective
R12421 T15715 T15716 themeOf GLε,transcription
R12422 T15716 T15717 themeOf transcription,defective
R12423 T15719 T15720 themeOf HOIP,deficient
R12424 T15721 T15722 themeOf HOIP,deficient
R12425 T15724 T15725 themeOf HOIP,deficient
R12426 T15730 T15731 themeOf GLε,transcripts
R12427 T15732 T15733 themeOf Hprt1,transcripts
R12428 T15734 T15735 themeOf HOIP,deficient
R12750 T16163 T16164 themeOf HOIP,deficient
R12751 T16166 T16167 themeOf HOIP,deficient
R12752 T16168 T16169 themeOf HOIP,deficient
R12753 T16173 T16174 themeOf CD154,expressing
R12754 T16176 T16175 themeOf CD154,lacking
R12755 T16178 T16177 equivalentTo pIκBα,Phospho-IκBα
R12756 T16181 T16182 themeOf HOIP,deficient
R13169 T16768 T16769 themeOf HOIP,deficient
R13170 T16771 T16770 themeOf recruitment,reduces
R13171 T16772 T16771 themeOf cIAP1,recruitment
R13172 T16773 T16771 themeOf CD40,recruitment
R13173 T16775 T16776 themeOf HOIP,recruitment
R13174 T16776 T16774 themeOf recruitment,modify
R13175 T16782 T16783 themeOf HOIP,deficient
R13176 T16793 T16794 themeOf HOIP,expression
R13177 T16796 T16797 themeOf HOIP,deficient
R13178 T16798 T16799 causeOf HOIP,dependent
R13179 T16800 T16799 themeOf recruitment,dependent
R13180 T16801 T16800 themeOf IKKγ,recruitment
R13181 T16802 T16800 themeOf CD40,recruitment
R13182 T16803 T16804 themeOf HOIP,deficient
R2101 T2812 T2813 themeOf HOIP,deficient
R2102 T2815 T2814 themeOf Rnf31,disruption
R2103 T2816 T2815 equivalentTo HOIP,Rnf31
R2104 T2817 T2818 themeOf HOIP,recruited
R2105 T2820 T2819 themeOf CD40,interaction
R2106 T2821 T2819 themeOf HOIP,interaction
R2107 T2822 T2826 themeOf recruitment,dependent
R2108 T2823 T2822 themeOf HOIP,recruitment
R2109 T2824 T2822 themeOf CD40,recruitment
R2110 T2825 T2826 causeOf TRAF2,dependent
R2111 T2834 T2833 themeOf HOIP,disrupt
R2112 T2837 T2836 equivalentTo HOIP,Rnf31
R2113 T2839 T2838 themeOf Rnf31,disrupted
R2114 T2841 T2840 themeOf Rnf31,disrupted
R2115 T2843 T2844 themeOf Rnf31,disrupted
R2116 T2845 T2846 themeOf HOIP,expression
R2117 T2847 T2848 themeOf HOIP,deficient
R2118 T2849 T2850 themeOf HOIP,deficient
R2119 T2852 T2851 themeOf Rnf31,disruption
R2120 T2853 T2854 themeOf HOIP,deficient
R2121 T2857 T2858 themeOf HOIP,expression
R2122 T2858 T2856 themeOf expression,restoring
R2123 T2859 T2860 themeOf HOIP,reconstituted
R2124 T2861 T2862 themeOf HOIP,deficient
R3207 T4174 T4176 causeOf HOIP,required
R3208 T4174 T4175 causeOf HOIP,required
R3209 T4178 T4175 themeOf mediated,required
R3210 T4179 T4176 themeOf mediated,required
R3211 T4180 T4181 themeOf CD80,upregulation
R3212 T4181 T4179 themeOf upregulation,mediated
R3213 T4182 T4178 themeOf activation,mediated
R3214 T4183 T4184 themeOf germline epsilon,transcription
R3215 T4184 T4182 themeOf transcription,activation
R3216 T4185 T4187 causeOf Engagement,upregulates
R3217 T4186 T4185 themeOf CD40,Engagement
R3218 T4188 T4187 themeOf expression,upregulates
R3219 T4189 T4188 themeOf CD80,expression
R3220 T4192 T4194 themeOf upregulation,induced
R3221 T4193 T4192 themeOf CD80,upregulation
R3222 T4195 T4194 causeOf engagement,induced
R3223 T4196 T4195 themeOf CD40,engagement
R3224 T4198 T4199 themeOf HOIP,reconstituted
R3225 T4200 T4201 causeOf CD40,stimulated
R3226 T4202 T4201 themeOf upregulation,stimulated
R3227 T4202 T4204 themeOf upregulation,reduced
R3228 T4203 T4202 themeOf CD80,upregulation
R3229 T4205 T4206 themeOf HOIP,deficient
R3230 T4206 T4204 causeOf deficient,reduced
R3231 T4208 T4207 themeOf CD80,upregulation
R3232 T4209 T4210 themeOf HOIP,reconstituted
R3233 T4211 T4216 themeOf defect,due
R3234 T4212 T4213 themeOf CD80,upregulation
R3235 T4213 T4211 themeOf upregulation,defect
R3236 T4214 T4215 themeOf HOIP,deficient
R3237 T4215 T4211 causeOf deficient,defect
R3238 T4217 T4216 causeOf disruption,due
R3239 T4218 T4217 themeOf Rnf31,disruption
R3240 T4226 T4225 themeOf germline epsilon,production
R3241 T4227 T4226 equivalentTo GLε,germline epsilon
R3242 T4230 T4231 themeOf GLε,transcription
R3243 T4231 T4229 themeOf transcription,induced
R3244 T4232 T4233 themeOf GLε,expression
R3245 T4234 T4235 themeOf HOIP,deficient
R3246 T4237 T4238 themeOf GLε,expression
R3247 T4238 T4239 themeOf expression,induced
R3248 T4240 T4241 themeOf HOIP,reconstituted
R38 T82 T81 equivalentTo HOIP,HOIL-1L Interacting Protein
R39 T86 T85 themeOf CD40,engagement
R40 T88 T85 themeOf CD154,engagement
R41 T90 T91 themeOf CD40,engagement
R4184 T5467 T5469 themeOf CD154,expressed
R4185 T5468 T5467 equivalentTo CD40 ligand,CD154
R4186 T5472 T5471 themeOf CD154,associated
R4187 T5474 T5473 themeOf sequestering,responsible
R4188 T5475 T5474 themeOf NF-κB subunits,sequestering
R4189 T5476 T5477 causeOf CD40,mediated
R4190 T5476 T5478 causeOf CD40,mediated
R4191 T5477 T5484 themeOf mediated,impaired
R4192 T5478 T5485 themeOf mediated,impaired
R4193 T5479 T5478 themeOf phosphorylation,mediated
R4194 T5480 T5477 themeOf degradation,mediated
R4195 T5481 T5480 themeOf IκBα,degradation
R4196 T5481 T5479 themeOf IκBα,phosphorylation
R4197 T5482 T5483 themeOf HOIP,deficient
R4198 T5486 T5487 themeOf CD40,engagement
R4199 T5489 T5490 themeOf HOIP,deficient
R42 T93 T94 causeOf TRAF2,mediates
R4200 T5492 T5493 themeOf HOIP,reconstituted
R4201 T5494 T5495 themeOf HOIP,expression
R43 T95 T94 themeOf recruitment,mediates
R44 T96 T95 themeOf HOIL-1L-interacting protein,recruitment
R45 T97 T96 equivalentTo HOIP,HOIL-1L-interacting protein
R46 T98 T99 partOf cytoplasmic domain,CD40
R47 T98 T95 themeOf cytoplasmic domain,recruitment
R48 T105 T104 themeOf HOIP,deficient
R49 T106 T107 causeOf CD40,induced
R50 T107 T110 themeOf induced,defective
R5001 T6574 T6575 causeOf HOIP,necessary
R5002 T6576 T6575 themeOf association,necessary
R5003 T6577 T6576 themeOf CD40,association
R5004 T6579 T6580 themeOf HOIP,deficient
R5005 T6582 T6583 themeOf HOIP,recruited
R5006 T6583 T6585 themeOf recruited,dependent
R5007 T6584 T6585 causeOf TRAF2,dependent
R5008 T6586 T6587 themeOf HOIP,functions downstream
R5009 T6588 T6587 causeOf TRAF2,functions downstream
R5010 T6589 T6590 themeOf TRAF2,associated
R5011 T6589 T6591 themeOf TRAF2,associated
R5012 T6592 T6590 themeOf cIAP1,associated
R5013 T6592 T6597 causeOf cIAP1,role
R5014 T6592 T6596 causeOf cIAP1,role
R5015 T6593 T6591 themeOf cIAP2,associated
R5016 T6593 T6594 causeOf cIAP2,role
R5017 T6593 T6595 causeOf cIAP2,role
R5018 T6598 T6597 themeOf recruitment,role
R5019 T6598 T6594 themeOf recruitment,role
R5020 T6599 T6596 themeOf recruitment,role
R5021 T6599 T6595 themeOf recruitment,role
R5022 T6600 T6598 themeOf HOIP,recruitment
R5023 T6600 T6599 themeOf HOIP,recruitment
R5024 T6601 T6598 themeOf TNFR1,recruitment
R5025 T6602 T6599 themeOf CD40,recruitment
R5026 T6603 T6606 themeOf association,altered
R5027 T6604 T6603 themeOf HOIP,association
R5028 T6605 T6603 themeOf CD40,association
R5029 T6608 T6609 themeOf cIAP1,associated
R5030 T6609 T6607 themeOf associated,reduced
R5031 T6612 T6611 themeOf decrease,resulted
R5032 T6613 T6612 themeOf HOIP,decrease
R5033 T6613 T6616 themeOf HOIP,increase
R5034 T6613 T6614 themeOf HOIP,recovered
R5035 T6613 T6617 themeOf HOIP,recognized
R5036 T6615 T6614 themeOf CD40,recovered
R5037 T6616 T6610 themeOf increase,resulted
R5038 T6619 T6618 themeOf HOIP,alter
R5039 T6621 T6622 themeOf CD40,associated
R5040 T6623 T6620 themeOf HOIP,alters
R5041 T6623 T6622 themeOf HOIP,associated
R5042 T6624 T6626 causeOf cIAP,influence
R5043 T6624 T6625 causeOf cIAP,influence
R5044 T6627 T6626 themeOf recruitment,influence
R5045 T6628 T6625 themeOf post-translational modification,influence
R5046 T6629 T6630 themeOf CD40,associated
R5047 T6631 T6627 themeOf HOIP,recruitment
R5048 T6631 T6628 themeOf HOIP,post-translational modification
R5049 T6631 T6630 themeOf HOIP,associated
R5050 T6632 T6633 causeOf HOIP,responsible
R5051 T6634 T6633 themeOf recruitment,responsible
R5052 T6635 T6634 themeOf CD40,recruitment
R5053 T6636 T6637 themeOf HOIP,deficient
R5054 T6638 T6639 themeOf HOIP,reconstituted
R5055 T6646 T6655 themeOf TRAF2,association
R5056 T6647 T6657 themeOf TRAF3,association
R5057 T6648 T6656 themeOf cIAP1,association
R5058 T6651 T6654 causeOf HOIP,required
R5059 T6651 T6653 causeOf HOIP,required
R5060 T6651 T6652 causeOf HOIP,required
R5061 T6655 T6654 themeOf association,required
R5062 T6656 T6652 themeOf association,required
R5063 T6657 T6653 themeOf association,required
R5064 T6658 T6655 themeOf CD40,association
R5065 T6658 T6657 themeOf CD40,association
R5066 T6658 T6656 themeOf CD40,association
R5067 T6663 T6664 themeOf HOIP,deficient
R5068 T6669 T6670 themeOf HOIP,reconstituted
R5069 T6672 T6673 themeOf HOIP,expression
R5070 T6673 T6671 themeOf expression,absence
R5071 T6682 T6681 themeOf IKKγ,expressing
R5072 T6683 T6686 themeOf recruitment,requires
R5073 T6684 T6683 themeOf IKKγ,recruitment
R5074 T6685 T6683 themeOf CD40,recruitment
R5075 T6687 T6686 causeOf HOIP,requires
R5076 T6690 T6691 themeOf CD40,associated
R5077 T6692 T6691 themeOf IKKγ,associated
R5078 T6693 T6694 themeOf CD40,associated
R5079 T6695 T6694 themeOf IKKγ,associated
R5080 T6695 T6696 themeOf IKKγ,phosphorylation
R5081 T6697 T6698 causeOf HOIP,required
R5082 T6699 T6698 themeOf association,required
R5083 T6699 T6702 causeOf association,coupled
R5084 T6700 T6699 themeOf IKKγ,association
R5085 T6701 T6699 themeOf CD40,association
R5086 T6703 T6702 themeOf post-translational modifications,coupled
R5087 T6704 T6703 themeOf IKKγ,post-translational modifications
R51 T108 T107 themeOf upregulation,induced
R52 T109 T108 themeOf CD80,upregulation
R53 T111 T112 themeOf HOIP,deficient
R54 T114 T115 themeOf HOIP,deficient
R55 T117 T118 themeOf HOIP,expression
R56 T118 T116 themeOf expression,Restoration
R6967 T9064 T9065 causeOf HOIP,dependent
R6968 T9066 T9067 causeOf CD40,mediated
R6969 T9067 T9065 themeOf mediated,dependent
R6970 T9068 T9067 themeOf upregulation,mediated
R6971 T9069 T9070 themeOf CD80,expression
R6972 T9070 T9068 themeOf expression,upregulation
R6973 T9071 T9072 themeOf HOIP,downstream
R6974 T9073 T9072 causeOf TRAF2,downstream
R6975 T9075 T9076 causeOf HOIP,role
R6976 T9077 T9076 themeOf promoting,role
R6977 T9078 T9077 themeOf recruitment,promoting
R6978 T9079 T9078 themeOf CD40,recruitment
R6979 T9082 T9083 themeOf CD40,engagement
R6980 T9092 T9091 themeOf IKKγ,interact
R6981 T9094 T9093 themeOf recruitment,mediates
R6982 T9095 T9094 themeOf IKKγ,recruitment
R6983 T9096 T9097 themeOf CD40,associated
R6984 T9098 T9097 themeOf HOIP,associated
R6985 T9098 T9099 causeOf HOIP,role
R6986 T9098 T9102 themeOf HOIP,recruitment
R6987 T9100 T9099 themeOf activating,role
R6988 T9101 T9100 themeOf IKKγ,activating
R6989 T9103 T9106 themeOf IKKγ,ubiquitination
R6990 T9103 T9105 themeOf IKKγ,phosphorylation
R6991 T9105 T9107 causeOf phosphorylation,reduce
R6992 T9105 T9110 causeOf phosphorylation,enhance
R6993 T9106 T9108 causeOf ubiquitination,reduce
R6994 T9106 T9109 causeOf ubiquitination,enhance
R6995 T9111 T9107 themeOf IKKγ,reduce
R6996 T9111 T9108 themeOf IKKγ,reduce
R6997 T9111 T9110 themeOf IKKγ,enhance
R6998 T9111 T9109 themeOf IKKγ,enhance
R6999 T9112 T9113 causeOf HOIP,mediates
R7000 T9114 T9113 themeOf recruitment,mediates
R7001 T9115 T9114 themeOf CD40,recruitment
R7002 T9116 T9117 themeOf HOIP,recruited
R7003 T9118 T9117 themeOf CD40,recruited
R7004 T9119 T9120 causeOf HOIP,functions as an adaptor
R7005 T9121 T9120 themeOf recruitment,functions as an adaptor
R7006 T9122 T9121 themeOf CD40,recruitment
R7007 T9124 T9125 themeOf IKKγ,binding
R7008 T9128 T9127 themeOf recruit,serve
R7009 T9129 T9128 themeOf IKKγ,recruit
R7010 T9131 T9130 themeOf recruitment,necessary
R7011 T9132 T9131 themeOf HOIP,recruitment
R7012 T9133 T9136 themeOf recruitment,dependent
R7013 T9134 T9133 themeOf HOIP,recruitment
R7014 T9135 T9136 causeOf TRAF2,dependent
R7015 T9137 T9139 themeOf TRAF2,interact
R7016 T9138 T9139 themeOf HOIP,interact
R7017 T9141 T9142 themeOf HOIP,bind
R7018 T9141 T9143 themeOf HOIP,associate
R7019 T9154 T9155 themeOf HOIP,deficiency
R7020 T9163 T9162 themeOf binding site,disruption
R7021 T9163 T9165 partOf binding site,CD40
R7022 T9167 T9166 themeOf receptor binding domain,deletion
R7023 T9167 T9168 partOf receptor binding domain,TRAF6
R7024 T9169 T9170 themeOf TRAF6,bind
R7025 T9171 T9170 themeOf CD40,bind
R7026 T9173 T9172 themeOf HOIP,absence
R7027 T9179 T9180 themeOf HOIP,interacts
R7028 T9181 T9180 themeOf SHARPIN,interacts
R7029 T9182 T9181 equivalentTo SHANK-associated RH domain interacting protein in postsynaptic density,SHARPIN
R7030 T9187 T9186 themeOf SHARPIN,link
R7031 T9188 T9186 themeOf HOIP,link
R7032 T9190 T9189 themeOf regulation,defects
R7033 T9191 T9190 themeOf HOIP,regulation
R776 T1117 T1118 themeOf CD154,expressed
R777 T1119 T1120 themeOf CD40,engagement
R778 T1122 T1124 themeOf cytoplasmic domain,recruitment
R779 T1122 T1123 partOf cytoplasmic domain,CD40
R780 T1125 T1131 themeOf TRAF1,binding
R781 T1126 T1132 themeOf TRAF2,binding
R782 T1127 T1133 themeOf TRAF3,binding
R783 T1128 T1130 themeOf TRAF6,binding
R784 T1134 T1131 themeOf cytoplasmic tail,binding
R785 T1134 T1135 partOf cytoplasmic tail,CD40
R786 T1134 T1132 themeOf cytoplasmic tail,binding
R787 T1134 T1133 themeOf cytoplasmic tail,binding
R788 T1134 T1130 themeOf cytoplasmic tail,binding
R789 T1139 T1137 themeOf CD40,associate
R790 T1139 T1136 themeOf CD40,associate
R791 T1139 T1138 themeOf CD40,associate
R792 T1140 T1137 themeOf TRAF3,associate
R793 T1141 T1136 themeOf TRAF2,associate
R794 T1142 T1138 themeOf TRAF6,associate
R795 T1143 T1145 themeOf HOIL-1L interacting protein,recruited
R796 T1144 T1143 equivalentTo HOIP,HOIL-1L interacting protein
R797 T1145 T1148 themeOf recruited,dependent
R798 T1146 T1145 themeOf CD40,recruited
R799 T1147 T1148 causeOf TRAF2,dependent
R800 T1148 T1149 themeOf dependent,following
R801 T1150 T1149 causeOf engagement,following
R802 T1151 T1150 themeOf CD40,engagement
R803 T1152 T1153 causeOf HOIP,functions downstream
R804 T1154 T1153 themeOf TRAF2,functions downstream
R805 T1158 T1157 themeOf expression,ablate
R806 T1159 T1158 themeOf HOIP,expression
R807 T1161 T1162 causeOf CD40,induced
R808 T1162 T1165 themeOf induced,defective
R809 T1163 T1162 themeOf upregulation,induced
R810 T1164 T1163 themeOf CD80,upregulation
R811 T1166 T1167 themeOf HOIP,deficient
R812 T1171 T1170 themeOf HOIP,absence
R813 T1173 T1174 themeOf HOIP,deficient
R814 T1176 T1175 themeOf CD40,association
R815 T1177 T1178 themeOf HOIP,deficient
R816 T1180 T1181 themeOf CD40,engagement
R9245 T11919 T11918 themeOf CD154,expressing
R9582 T12312 T12313 themeOf HOIP,deficient
R9583 T12315 T12316 themeOf Rnf31,disrupted
R9584 T12318 T12319 themeOf HOIP,expression