| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T2771 |
51-66 |
Protein |
denotes |
SHARPIN protein |
| T2772 |
210-217 |
Protein |
denotes |
SHARPIN |
| T2773 |
256-265 |
Protein |
denotes |
ubiquitin |
| T2774 |
291-324 |
Protein |
denotes |
zinc-finger Ran-binding protein 2 |
| T2775 |
326-331 |
Protein |
denotes |
ZFRBP |
| T2776 |
333-339 |
Entity |
denotes |
domain |
| T2779 |
409-416 |
Gene_expression |
denotes |
present |
| T2777 |
424-439 |
Protein |
denotes |
SHARPIN protein |
| T2778 |
488-495 |
Protein |
denotes |
SHARPIN |
| T2780 |
581-593 |
Protein |
denotes |
Sharpin gene |
| T2782 |
798-808 |
Transcription |
denotes |
expression |
| T2781 |
812-819 |
Protein |
denotes |
Sharpin |
| T2783 |
952-964 |
Protein |
denotes |
Sharpin mRNA |
| T2784 |
1045-1054 |
Negative_regulation |
denotes |
decreased |
| T2786 |
1099-1108 |
Negative_regulation |
denotes |
reduction |
| T2785 |
1112-1124 |
Protein |
denotes |
Sharpin mRNA |
| T2790 |
1170-1182 |
Gene_expression |
denotes |
Transfection |
| T2791 |
1170-1182 |
Positive_regulation |
denotes |
Transfection |
| T2787 |
1198-1205 |
Protein |
denotes |
Sharpin |
| T2792 |
1267-1278 |
Entity |
denotes |
cytoplasmic |
| T2793 |
1279-1291 |
Localization |
denotes |
localization |
| T2794 |
1279-1291 |
Localization |
denotes |
localization |
| T2788 |
1299-1314 |
Protein |
denotes |
SHARPIN protein |
| T2789 |
1316-1323 |
Protein |
denotes |
Fig. 1E |
| T13246 |
1403-1410 |
Protein |
denotes |
SHARPIN |
| T13247 |
1507-1510 |
Protein |
denotes |
UBL |
| T13248 |
1512-1521 |
Protein |
denotes |
ubiquitin |
| T13249 |
1539-1544 |
Protein |
denotes |
ZFRBP |
| T13250 |
1546-1579 |
Protein |
denotes |
zinc-finger Ran-Binding protein 2 |
| T13251 |
1629-1644 |
Protein |
denotes |
SHARPIN protein |
| T13252 |
2004-2011 |
Protein |
denotes |
Sharpin |
| T13254 |
2071-2081 |
Transcription |
denotes |
expression |
| T13253 |
2100-2107 |
Protein |
denotes |
WT BMDC |
| T13255 |
2452-2456 |
Protein |
denotes |
FLAG |
| T13256 |
2457-2464 |
Protein |
denotes |
SHARPIN |
| T4275 |
5700-5708 |
Positive_regulation |
denotes |
resulted |
| T4276 |
5700-5708 |
Positive_regulation |
denotes |
resulted |
| T4277 |
5700-5708 |
Positive_regulation |
denotes |
resulted |
| T4270 |
5712-5721 |
Localization |
denotes |
secretion |
| T4271 |
5712-5721 |
Localization |
denotes |
secretion |
| T4272 |
5712-5721 |
Localization |
denotes |
secretion |
| T4265 |
5725-5728 |
Protein |
denotes |
IL6 |
| T4266 |
5730-5737 |
Protein |
denotes |
IL12P70 |
| T4267 |
5743-5748 |
Protein |
denotes |
GMCSF |
| T4273 |
5806-5814 |
Gene_expression |
denotes |
produced |
| T4274 |
5806-5814 |
Gene_expression |
denotes |
produced |
| T4268 |
5871-5878 |
Protein |
denotes |
WT BMDC |
| T4269 |
5880-5883 |
Protein |
denotes |
Fig |
| T4278 |
6089-6096 |
Protein |
denotes |
Sharpin |
| T4279 |
6097-6106 |
Negative_regulation |
denotes |
deficient |
| T4280 |
6144-6151 |
Protein |
denotes |
Sharpin |
| T4284 |
6262-6270 |
Localization |
denotes |
secreted |
| T4281 |
6290-6297 |
Protein |
denotes |
IL12P70 |
| T4286 |
6357-6361 |
Positive_regulation |
denotes |
role |
| T4282 |
6365-6372 |
Protein |
denotes |
SHARPIN |
| T4285 |
6381-6391 |
Gene_expression |
denotes |
production |
| T4283 |
6395-6402 |
Protein |
denotes |
IL12P70 |
| T4289 |
6432-6438 |
Transcription |
denotes |
levels |
| T4290 |
6432-6438 |
Transcription |
denotes |
levels |
| T4287 |
6459-6472 |
Protein |
denotes |
cytokines Il6 |
| T4288 |
6474-6481 |
Protein |
denotes |
Il12p40 |
| T4291 |
6547-6554 |
Negative_regulation |
denotes |
reduced |
| T4292 |
6547-6554 |
Negative_regulation |
denotes |
reduced |
| T14226 |
6944-6951 |
Protein |
denotes |
IL12P70 |
| T14227 |
6953-6956 |
Protein |
denotes |
IL6 |
| T14228 |
6962-6967 |
Protein |
denotes |
GMCSF |
| T14229 |
7174-7181 |
Protein |
denotes |
IL12P70 |
| T14230 |
7186-7189 |
Protein |
denotes |
IL6 |
| T14231 |
7255-7277 |
Protein |
denotes |
Sharpin-containing BAC |
| T14232 |
7514-7521 |
Protein |
denotes |
IL12P70 |
| T14233 |
7522-7532 |
Gene_expression |
denotes |
production |
| T14538 |
7936-7939 |
Protein |
denotes |
qRT |
| T5633 |
8198-8203 |
Protein |
denotes |
NF-κB |
| T5636 |
8448-8457 |
Positive_regulation |
denotes |
increased |
| T5635 |
8458-8468 |
Gene_expression |
denotes |
expression |
| T5634 |
8495-8498 |
Protein |
denotes |
TLR |
| T5643 |
8585-8595 |
Gene_expression |
denotes |
expression |
| T5644 |
8585-8595 |
Gene_expression |
denotes |
expression |
| T5637 |
8603-8615 |
Protein |
denotes |
LPS receptor |
| T5638 |
8639-8643 |
Protein |
denotes |
TLR4 |
| T5639 |
8668-8672 |
Protein |
denotes |
CD14 |
| T5640 |
8677-8709 |
Protein |
denotes |
myeloid differentiation factor 2 |
| T5641 |
8711-8714 |
Protein |
denotes |
MD2 |
| T5642 |
8715-8719 |
Protein |
denotes |
LY96 |
| T5648 |
8767-8777 |
Gene_expression |
denotes |
expression |
| T5649 |
8767-8777 |
Gene_expression |
denotes |
expression |
| T5650 |
8767-8777 |
Gene_expression |
denotes |
expression |
| T5645 |
8788-8792 |
Protein |
denotes |
CD14 |
| T5646 |
8797-8801 |
Protein |
denotes |
TLR4 |
| T5647 |
8802-8805 |
Protein |
denotes |
MD2 |
| T5653 |
8878-8887 |
Localization |
denotes |
secretion |
| T5651 |
8907-8921 |
Protein |
denotes |
cytokines IL10 |
| T5655 |
8931-8938 |
Negative_regulation |
denotes |
inhibit |
| T5652 |
8939-8943 |
Protein |
denotes |
IL12 |
| T5654 |
8944-8953 |
Localization |
denotes |
secretion |
| T5656 |
9076-9080 |
Protein |
denotes |
IL10 |
| T5659 |
9086-9096 |
Positive_regulation |
denotes |
stimulated |
| T5657 |
9132-9136 |
Protein |
denotes |
IL10 |
| T5661 |
9145-9156 |
Positive_regulation |
denotes |
responsible |
| T5662 |
9161-9170 |
Negative_regulation |
denotes |
decreased |
| T5660 |
9171-9180 |
Localization |
denotes |
secretion |
| T5658 |
9184-9191 |
Protein |
denotes |
IL12P70 |
| T5665 |
9206-9215 |
Positive_regulation |
denotes |
Increased |
| T5664 |
9216-9226 |
Gene_expression |
denotes |
expression |
| T5663 |
9254-9257 |
Protein |
denotes |
TLR |
| T5666 |
9356-9359 |
Protein |
denotes |
A20 |
| T5670 |
9433-9439 |
Positive_regulation |
denotes |
ruling |
| T5671 |
9433-9439 |
Positive_regulation |
denotes |
ruling |
| T5668 |
9444-9458 |
Gene_expression |
denotes |
overexpression |
| T5669 |
9444-9458 |
Positive_regulation |
denotes |
overexpression |
| T5667 |
9462-9465 |
Protein |
denotes |
A20 |
| T14953 |
9565-9569 |
Protein |
denotes |
TLR4 |
| T14954 |
9574-9577 |
Protein |
denotes |
MD2 |
| T14956 |
9578-9588 |
Gene_expression |
denotes |
expression |
| T14957 |
9578-9588 |
Gene_expression |
denotes |
expression |
| T14958 |
9593-9602 |
Negative_regulation |
denotes |
decreased |
| T14959 |
9593-9602 |
Negative_regulation |
denotes |
decreased |
| T14961 |
9593-9602 |
Negative_regulation |
denotes |
decreased |
| T14955 |
9603-9607 |
Protein |
denotes |
IL10 |
| T14960 |
9608-9617 |
Localization |
denotes |
secretion |
| T14962 |
9727-9731 |
Protein |
denotes |
TLR4 |
| T14963 |
9732-9735 |
Protein |
denotes |
MD2 |
| T14964 |
9744-9748 |
Protein |
denotes |
CD14 |
| T14965 |
10038-10042 |
Protein |
denotes |
IL10 |
| T14966 |
10243-10246 |
Protein |
denotes |
qRT |
| T14968 |
10266-10276 |
Gene_expression |
denotes |
production |
| T14967 |
10280-10283 |
Protein |
denotes |
A20 |
| T5672 |
10309-10313 |
Protein |
denotes |
TLR3 |
| T5676 |
10365-10374 |
Regulation |
denotes |
regulated |
| T5677 |
10365-10374 |
Regulation |
denotes |
regulated |
| T5678 |
10365-10374 |
Regulation |
denotes |
regulated |
| T5673 |
10421-10426 |
Protein |
denotes |
NF-κB |
| T5674 |
10428-10432 |
Protein |
denotes |
TBK1 |
| T5675 |
10433-10437 |
Protein |
denotes |
IRF3 |
| T5679 |
10491-10496 |
Protein |
denotes |
NF-κB |
| T5680 |
10498-10502 |
Protein |
denotes |
TBK1 |
| T5681 |
10503-10507 |
Protein |
denotes |
IRF3 |
| T5682 |
10516-10520 |
Protein |
denotes |
MAPK |
| T5683 |
10593-10600 |
Protein |
denotes |
Sharpin |
| T5684 |
10601-10610 |
Negative_regulation |
denotes |
deficient |
| T5699 |
10617-10633 |
Positive_regulation |
denotes |
Stimulus-induced |
| T5700 |
10617-10633 |
Positive_regulation |
denotes |
Stimulus-induced |
| T5691 |
10634-10649 |
Phosphorylation |
denotes |
phosphorylation |
| T5692 |
10634-10649 |
Phosphorylation |
denotes |
phosphorylation |
| T5685 |
10657-10667 |
Protein |
denotes |
IκB kinase |
| T5686 |
10669-10675 |
Protein |
denotes |
IKK1/2 |
| T5687 |
10701-10706 |
Protein |
denotes |
NF-κB |
| T5701 |
10718-10726 |
Positive_regulation |
denotes |
allowing |
| T5702 |
10718-10726 |
Positive_regulation |
denotes |
allowing |
| T5703 |
10718-10726 |
Positive_regulation |
denotes |
allowing |
| T5693 |
10727-10742 |
Phosphorylation |
denotes |
phosphorylation |
| T5694 |
10727-10742 |
Phosphorylation |
denotes |
phosphorylation |
| T5704 |
10747-10766 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5705 |
10747-10766 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5706 |
10747-10766 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5695 |
10767-10778 |
Protein_catabolism |
denotes |
degradation |
| T5696 |
10767-10778 |
Protein_catabolism |
denotes |
degradation |
| T5697 |
10767-10778 |
Protein_catabolism |
denotes |
degradation |
| T5688 |
10786-10791 |
Protein |
denotes |
NF-κB |
| T5689 |
10802-10806 |
Protein |
denotes |
IκBα |
| T5707 |
10810-10817 |
Localization |
denotes |
release |
| T5690 |
10822-10849 |
Protein |
denotes |
NF-κB transcription factors |
| T5698 |
10859-10866 |
Entity |
denotes |
nucleus |
| T5716 |
11064-11073 |
Negative_regulation |
denotes |
exhibited |
| T5717 |
11064-11073 |
Negative_regulation |
denotes |
exhibited |
| T5711 |
11082-11088 |
Positive_regulation |
denotes |
levels |
| T5712 |
11082-11088 |
Positive_regulation |
denotes |
levels |
| T5718 |
11082-11088 |
Positive_regulation |
denotes |
levels |
| T5719 |
11082-11088 |
Positive_regulation |
denotes |
levels |
| T5720 |
11082-11088 |
Positive_regulation |
denotes |
levels |
| T5708 |
11092-11096 |
Protein |
denotes |
TBK1 |
| T5709 |
11098-11104 |
Protein |
denotes |
ERK1/2 |
| T5710 |
11110-11113 |
Protein |
denotes |
p38 |
| T5713 |
11114-11129 |
Phosphorylation |
denotes |
phosphorylation |
| T5714 |
11114-11129 |
Phosphorylation |
denotes |
phosphorylation |
| T5715 |
11114-11129 |
Phosphorylation |
denotes |
phosphorylation |
| T5727 |
11193-11200 |
Negative_regulation |
denotes |
absence |
| T5721 |
11215-11235 |
Protein |
denotes |
SHARPIN decreased NF |
| T5722 |
11236-11238 |
Protein |
denotes |
κB |
| T5728 |
11239-11249 |
Positive_regulation |
denotes |
activation |
| T5729 |
11262-11268 |
Regulation |
denotes |
affect |
| T5730 |
11262-11268 |
Regulation |
denotes |
affect |
| T5731 |
11262-11268 |
Regulation |
denotes |
affect |
| T5723 |
11269-11273 |
Protein |
denotes |
TBK1 |
| T5724 |
11274-11278 |
Protein |
denotes |
IRF3 |
| T5725 |
11280-11284 |
Protein |
denotes |
ERK1 |
| T5726 |
11292-11295 |
Protein |
denotes |
p38 |
| T15304 |
11359-11369 |
Negative_regulation |
denotes |
Inhibition |
| T15303 |
11373-11378 |
Protein |
denotes |
NF-κB |
| T15305 |
11660-11665 |
Protein |
denotes |
NF-κB |
| T15306 |
11667-11671 |
Protein |
denotes |
TBK1 |
| T15307 |
11672-11676 |
Protein |
denotes |
IRF3 |
| T15308 |
11678-11682 |
Protein |
denotes |
ERK1 |
| T15309 |
11690-11693 |
Protein |
denotes |
p38 |
| T15310 |
11714-11718 |
Protein |
denotes |
Beta |
| T15311 |
11719-11724 |
Protein |
denotes |
actin |
| T15315 |
11767-11773 |
Gene_expression |
denotes |
levels |
| T15312 |
11790-11796 |
Protein |
denotes |
p-IκBα |
| T15313 |
11855-11861 |
Protein |
denotes |
ImageJ |
| T15314 |
11863-11866 |
Protein |
denotes |
NIH |
| T6556 |
12021-12030 |
Negative_regulation |
denotes |
defective |
| T6553 |
12031-12035 |
Protein |
denotes |
IL12 |
| T6555 |
12036-12046 |
Gene_expression |
denotes |
production |
| T6554 |
12136-12143 |
Protein |
denotes |
SHARPIN |
| T6557 |
12262-12266 |
Protein |
denotes |
CD4+ |
| T6558 |
12280-12287 |
Protein |
denotes |
WT BMDC |
| T6559 |
12382-12386 |
Protein |
denotes |
IFNγ |
| T6560 |
12493-12496 |
Protein |
denotes |
Th1 |
| T6561 |
12568-12587 |
Protein |
denotes |
TLR2 ligand Pam3CYS |
| T6564 |
12624-12630 |
Positive_regulation |
denotes |
induce |
| T6565 |
12624-12630 |
Positive_regulation |
denotes |
induce |
| T6562 |
12636-12639 |
Protein |
denotes |
Th1 |
| T6563 |
12644-12647 |
Protein |
denotes |
Th2 |
| T6566 |
12685-12692 |
Protein |
denotes |
WT BMDC |
| T6569 |
12693-12700 |
Positive_regulation |
denotes |
induced |
| T6567 |
12701-12712 |
Protein |
denotes |
robust IFNγ |
| T6568 |
12713-12723 |
Gene_expression |
denotes |
production |
| T6573 |
12786-12793 |
Negative_regulation |
denotes |
reduced |
| T6570 |
12794-12797 |
Protein |
denotes |
Th1 |
| T6575 |
12874-12880 |
Negative_regulation |
denotes |
report |
| T6576 |
12884-12893 |
Negative_regulation |
denotes |
decreased |
| T6571 |
12894-12898 |
Protein |
denotes |
IL12 |
| T6574 |
12899-12909 |
Gene_expression |
denotes |
production |
| T6572 |
12940-12944 |
Protein |
denotes |
TLR2 |
| T6577 |
12994-12997 |
Protein |
denotes |
IL4 |
| T6579 |
13135-13145 |
Gene_expression |
denotes |
production |
| T6578 |
13149-13177 |
Protein |
denotes |
Th17-specific cytokine IL17A |
| T6580 |
13321-13324 |
Protein |
denotes |
Th1 |
| T6586 |
13395-13404 |
Positive_regulation |
denotes |
effective |
| T6581 |
13408-13411 |
Protein |
denotes |
IL2 |
| T6584 |
13412-13422 |
Gene_expression |
denotes |
production |
| T6582 |
13490-13497 |
Protein |
denotes |
WT BMDC |
| T6585 |
13498-13505 |
Positive_regulation |
denotes |
induced |
| T6583 |
13511-13514 |
Protein |
denotes |
IL2 |
| T6587 |
13631-13635 |
Protein |
denotes |
CD4+ |
| T15733 |
13837-13841 |
Protein |
denotes |
CD4+ |
| T15734 |
13908-13927 |
Protein |
denotes |
MHC haplotype: H-2b |
| T15735 |
14106-14110 |
Protein |
denotes |
CD4+ |
| T15736 |
14161-14174 |
Protein |
denotes |
MHC haplotype |
| T15740 |
14233-14242 |
Localization |
denotes |
secretion |
| T15741 |
14233-14242 |
Localization |
denotes |
secretion |
| T15742 |
14233-14242 |
Localization |
denotes |
secretion |
| T15737 |
14246-14250 |
Protein |
denotes |
IFNγ |
| T15738 |
14252-14255 |
Protein |
denotes |
IL4 |
| T15739 |
14261-14264 |
Protein |
denotes |
IL2 |
| R11003 |
T13253 |
T13254 |
themeOf |
WT BMDC,expression |
| R11889 |
T14232 |
T14233 |
themeOf |
IL12P70,production |
| R12530 |
T14953 |
T14956 |
themeOf |
TLR4,expression |
| R12531 |
T14954 |
T14957 |
themeOf |
MD2,expression |
| R12532 |
T14955 |
T14960 |
themeOf |
IL10,secretion |
| R12533 |
T14956 |
T14958 |
themeOf |
expression,decreased |
| R12534 |
T14957 |
T14959 |
themeOf |
expression,decreased |
| R12535 |
T14960 |
T14961 |
themeOf |
secretion,decreased |
| R12536 |
T14967 |
T14968 |
themeOf |
A20,production |
| R12792 |
T15303 |
T15304 |
themeOf |
NF-κB,Inhibition |
| R12793 |
T15312 |
T15315 |
themeOf |
p-IκBα,levels |
| R13166 |
T15737 |
T15740 |
themeOf |
IFNγ,secretion |
| R13167 |
T15738 |
T15741 |
themeOf |
IL4,secretion |
| R13168 |
T15739 |
T15742 |
themeOf |
IL2,secretion |
| R2284 |
T2772 |
T2776 |
partOf |
SHARPIN,domain |
| R2285 |
T2774 |
T2776 |
partOf |
zinc-finger Ran-binding protein 2,domain |
| R2286 |
T2775 |
T2776 |
partOf |
ZFRBP,domain |
| R2287 |
T2777 |
T2779 |
themeOf |
SHARPIN protein,present |
| R2288 |
T2781 |
T2782 |
themeOf |
Sharpin,expression |
| R2289 |
T2783 |
T2784 |
themeOf |
Sharpin mRNA,decreased |
| R2290 |
T2785 |
T2786 |
themeOf |
Sharpin mRNA,reduction |
| R2291 |
T2787 |
T2790 |
themeOf |
Sharpin,Transfection |
| R2292 |
T2788 |
T2793 |
themeOf |
SHARPIN protein,localization |
| R2293 |
T2789 |
T2794 |
themeOf |
Fig. 1E,localization |
| R2294 |
T2790 |
T2791 |
themeOf |
Transfection,Transfection |
| R2295 |
T2792 |
T2793 |
locationOf |
cytoplasmic,localization |
| R2296 |
T2792 |
T2794 |
locationOf |
cytoplasmic,localization |
| R3530 |
T4265 |
T4270 |
themeOf |
IL6,secretion |
| R3531 |
T4266 |
T4271 |
themeOf |
IL12P70,secretion |
| R3532 |
T4267 |
T4272 |
themeOf |
GMCSF,secretion |
| R3533 |
T4268 |
T4273 |
themeOf |
WT BMDC,produced |
| R3534 |
T4269 |
T4274 |
themeOf |
Fig,produced |
| R3535 |
T4270 |
T4275 |
themeOf |
secretion,resulted |
| R3536 |
T4271 |
T4276 |
themeOf |
secretion,resulted |
| R3537 |
T4272 |
T4277 |
themeOf |
secretion,resulted |
| R3538 |
T4278 |
T4279 |
themeOf |
Sharpin,deficient |
| R3539 |
T4281 |
T4284 |
themeOf |
IL12P70,secreted |
| R3540 |
T4282 |
T4286 |
causeOf |
SHARPIN,role |
| R3541 |
T4283 |
T4285 |
themeOf |
IL12P70,production |
| R3542 |
T4285 |
T4286 |
themeOf |
production,role |
| R3543 |
T4287 |
T4289 |
themeOf |
cytokines Il6,levels |
| R3544 |
T4288 |
T4290 |
themeOf |
Il12p40,levels |
| R3545 |
T4289 |
T4291 |
themeOf |
levels,reduced |
| R3546 |
T4290 |
T4292 |
themeOf |
levels,reduced |
| R4542 |
T5634 |
T5635 |
themeOf |
TLR,expression |
| R4543 |
T5635 |
T5636 |
themeOf |
expression,increased |
| R4544 |
T5637 |
T5643 |
themeOf |
LPS receptor,expression |
| R4545 |
T5638 |
T5644 |
themeOf |
TLR4,expression |
| R4546 |
T5645 |
T5648 |
themeOf |
CD14,expression |
| R4547 |
T5646 |
T5649 |
themeOf |
TLR4,expression |
| R4548 |
T5647 |
T5650 |
themeOf |
MD2,expression |
| R4549 |
T5651 |
T5653 |
themeOf |
cytokines IL10,secretion |
| R4550 |
T5651 |
T5655 |
causeOf |
cytokines IL10,inhibit |
| R4551 |
T5652 |
T5654 |
themeOf |
IL12,secretion |
| R4552 |
T5654 |
T5655 |
themeOf |
secretion,inhibit |
| R4553 |
T5656 |
T5659 |
themeOf |
IL10,stimulated |
| R4554 |
T5657 |
T5661 |
causeOf |
IL10,responsible |
| R4555 |
T5658 |
T5660 |
themeOf |
IL12P70,secretion |
| R4556 |
T5660 |
T5661 |
themeOf |
secretion,responsible |
| R4557 |
T5660 |
T5662 |
themeOf |
secretion,decreased |
| R4558 |
T5663 |
T5664 |
themeOf |
TLR,expression |
| R4559 |
T5664 |
T5665 |
themeOf |
expression,Increased |
| R4560 |
T5667 |
T5668 |
themeOf |
A20,overexpression |
| R4561 |
T5668 |
T5669 |
themeOf |
overexpression,overexpression |
| R4562 |
T5668 |
T5670 |
themeOf |
overexpression,ruling |
| R4563 |
T5669 |
T5671 |
themeOf |
overexpression,ruling |
| R4564 |
T5673 |
T5676 |
themeOf |
NF-κB,regulated |
| R4565 |
T5674 |
T5677 |
themeOf |
TBK1,regulated |
| R4566 |
T5675 |
T5678 |
themeOf |
IRF3,regulated |
| R4567 |
T5683 |
T5684 |
themeOf |
Sharpin,deficient |
| R4568 |
T5685 |
T5691 |
themeOf |
IκB kinase,phosphorylation |
| R4569 |
T5686 |
T5692 |
themeOf |
IKK1/2,phosphorylation |
| R4570 |
T5686 |
T5695 |
themeOf |
IKK1/2,degradation |
| R4571 |
T5688 |
T5693 |
themeOf |
NF-κB,phosphorylation |
| R4572 |
T5688 |
T5696 |
themeOf |
NF-κB,degradation |
| R4573 |
T5689 |
T5694 |
themeOf |
IκBα,phosphorylation |
| R4574 |
T5689 |
T5697 |
themeOf |
IκBα,degradation |
| R4575 |
T5690 |
T5707 |
themeOf |
NF-κB transcription factors,release |
| R4576 |
T5691 |
T5699 |
themeOf |
phosphorylation,Stimulus-induced |
| R4577 |
T5692 |
T5700 |
themeOf |
phosphorylation,Stimulus-induced |
| R4578 |
T5695 |
T5701 |
themeOf |
degradation,allowing |
| R4579 |
T5695 |
T5704 |
themeOf |
degradation,proteasome-mediated |
| R4580 |
T5696 |
T5702 |
themeOf |
degradation,allowing |
| R4581 |
T5696 |
T5705 |
themeOf |
degradation,proteasome-mediated |
| R4582 |
T5697 |
T5703 |
themeOf |
degradation,allowing |
| R4583 |
T5697 |
T5706 |
themeOf |
degradation,proteasome-mediated |
| R4584 |
T5698 |
T5707 |
locationOf |
nucleus,release |
| R4585 |
T5708 |
T5711 |
themeOf |
TBK1,levels |
| R4586 |
T5708 |
T5713 |
themeOf |
TBK1,phosphorylation |
| R4587 |
T5709 |
T5712 |
themeOf |
ERK1/2,levels |
| R4588 |
T5709 |
T5714 |
themeOf |
ERK1/2,phosphorylation |
| R4589 |
T5710 |
T5715 |
themeOf |
p38,phosphorylation |
| R4590 |
T5711 |
T5716 |
themeOf |
levels,exhibited |
| R4591 |
T5712 |
T5717 |
themeOf |
levels,exhibited |
| R4592 |
T5713 |
T5718 |
themeOf |
phosphorylation,levels |
| R4593 |
T5714 |
T5719 |
themeOf |
phosphorylation,levels |
| R4594 |
T5715 |
T5720 |
themeOf |
phosphorylation,levels |
| R4595 |
T5721 |
T5727 |
themeOf |
SHARPIN decreased NF,absence |
| R4596 |
T5722 |
T5728 |
themeOf |
κB,activation |
| R4597 |
T5723 |
T5729 |
themeOf |
TBK1,affect |
| R4598 |
T5724 |
T5730 |
themeOf |
IRF3,affect |
| R4599 |
T5725 |
T5731 |
themeOf |
ERK1,affect |
| R4600 |
T5727 |
T5729 |
causeOf |
absence,affect |
| R4601 |
T5727 |
T5730 |
causeOf |
absence,affect |
| R4602 |
T5727 |
T5731 |
causeOf |
absence,affect |
| R5313 |
T6553 |
T6555 |
themeOf |
IL12,production |
| R5314 |
T6555 |
T6556 |
themeOf |
production,defective |
| R5315 |
T6562 |
T6564 |
themeOf |
Th1,induce |
| R5316 |
T6563 |
T6565 |
themeOf |
Th2,induce |
| R5317 |
T6566 |
T6569 |
causeOf |
WT BMDC,induced |
| R5318 |
T6567 |
T6568 |
themeOf |
robust IFNγ,production |
| R5319 |
T6568 |
T6569 |
themeOf |
production,induced |
| R5320 |
T6570 |
T6573 |
themeOf |
Th1,reduced |
| R5321 |
T6571 |
T6574 |
themeOf |
IL12,production |
| R5322 |
T6574 |
T6575 |
themeOf |
production,report |
| R5323 |
T6574 |
T6576 |
themeOf |
production,decreased |
| R5324 |
T6578 |
T6579 |
themeOf |
Th17-specific cytokine IL17A,production |
| R5325 |
T6581 |
T6584 |
themeOf |
IL2,production |
| R5326 |
T6582 |
T6585 |
causeOf |
WT BMDC,induced |
| R5327 |
T6583 |
T6585 |
themeOf |
IL2,induced |
| R5328 |
T6584 |
T6586 |
themeOf |
production,effective |
