| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T5633 |
82-87 |
Protein |
denotes |
NF-κB |
| T5636 |
332-341 |
Positive_regulation |
denotes |
increased |
| T5635 |
342-352 |
Gene_expression |
denotes |
expression |
| T5634 |
379-382 |
Protein |
denotes |
TLR |
| T5643 |
469-479 |
Gene_expression |
denotes |
expression |
| T5644 |
469-479 |
Gene_expression |
denotes |
expression |
| T5637 |
487-499 |
Protein |
denotes |
LPS receptor |
| T5638 |
523-527 |
Protein |
denotes |
TLR4 |
| T5639 |
552-556 |
Protein |
denotes |
CD14 |
| T5640 |
561-593 |
Protein |
denotes |
myeloid differentiation factor 2 |
| T5641 |
595-598 |
Protein |
denotes |
MD2 |
| T5642 |
599-603 |
Protein |
denotes |
LY96 |
| T5648 |
651-661 |
Gene_expression |
denotes |
expression |
| T5649 |
651-661 |
Gene_expression |
denotes |
expression |
| T5650 |
651-661 |
Gene_expression |
denotes |
expression |
| T5645 |
672-676 |
Protein |
denotes |
CD14 |
| T5646 |
681-685 |
Protein |
denotes |
TLR4 |
| T5647 |
686-689 |
Protein |
denotes |
MD2 |
| T5653 |
762-771 |
Localization |
denotes |
secretion |
| T5651 |
791-805 |
Protein |
denotes |
cytokines IL10 |
| T5655 |
815-822 |
Negative_regulation |
denotes |
inhibit |
| T5652 |
823-827 |
Protein |
denotes |
IL12 |
| T5654 |
828-837 |
Localization |
denotes |
secretion |
| T5656 |
960-964 |
Protein |
denotes |
IL10 |
| T5659 |
970-980 |
Positive_regulation |
denotes |
stimulated |
| T5657 |
1016-1020 |
Protein |
denotes |
IL10 |
| T5661 |
1029-1040 |
Positive_regulation |
denotes |
responsible |
| T5662 |
1045-1054 |
Negative_regulation |
denotes |
decreased |
| T5660 |
1055-1064 |
Localization |
denotes |
secretion |
| T5658 |
1068-1075 |
Protein |
denotes |
IL12P70 |
| T5665 |
1090-1099 |
Positive_regulation |
denotes |
Increased |
| T5664 |
1100-1110 |
Gene_expression |
denotes |
expression |
| T5663 |
1138-1141 |
Protein |
denotes |
TLR |
| T5666 |
1240-1243 |
Protein |
denotes |
A20 |
| T5670 |
1317-1323 |
Positive_regulation |
denotes |
ruling |
| T5671 |
1317-1323 |
Positive_regulation |
denotes |
ruling |
| T5668 |
1328-1342 |
Gene_expression |
denotes |
overexpression |
| T5669 |
1328-1342 |
Positive_regulation |
denotes |
overexpression |
| T5667 |
1346-1349 |
Protein |
denotes |
A20 |
| T14953 |
1449-1453 |
Protein |
denotes |
TLR4 |
| T14954 |
1458-1461 |
Protein |
denotes |
MD2 |
| T14956 |
1462-1472 |
Gene_expression |
denotes |
expression |
| T14957 |
1462-1472 |
Gene_expression |
denotes |
expression |
| T14958 |
1477-1486 |
Negative_regulation |
denotes |
decreased |
| T14959 |
1477-1486 |
Negative_regulation |
denotes |
decreased |
| T14961 |
1477-1486 |
Negative_regulation |
denotes |
decreased |
| T14955 |
1487-1491 |
Protein |
denotes |
IL10 |
| T14960 |
1492-1501 |
Localization |
denotes |
secretion |
| T14962 |
1611-1615 |
Protein |
denotes |
TLR4 |
| T14963 |
1616-1619 |
Protein |
denotes |
MD2 |
| T14964 |
1628-1632 |
Protein |
denotes |
CD14 |
| T14965 |
1922-1926 |
Protein |
denotes |
IL10 |
| T14966 |
2127-2130 |
Protein |
denotes |
qRT |
| T14968 |
2150-2160 |
Gene_expression |
denotes |
production |
| T14967 |
2164-2167 |
Protein |
denotes |
A20 |
| T5672 |
2193-2197 |
Protein |
denotes |
TLR3 |
| T5676 |
2249-2258 |
Regulation |
denotes |
regulated |
| T5677 |
2249-2258 |
Regulation |
denotes |
regulated |
| T5678 |
2249-2258 |
Regulation |
denotes |
regulated |
| T5673 |
2305-2310 |
Protein |
denotes |
NF-κB |
| T5674 |
2312-2316 |
Protein |
denotes |
TBK1 |
| T5675 |
2317-2321 |
Protein |
denotes |
IRF3 |
| T5679 |
2375-2380 |
Protein |
denotes |
NF-κB |
| T5680 |
2382-2386 |
Protein |
denotes |
TBK1 |
| T5681 |
2387-2391 |
Protein |
denotes |
IRF3 |
| T5682 |
2400-2404 |
Protein |
denotes |
MAPK |
| T5683 |
2477-2484 |
Protein |
denotes |
Sharpin |
| T5684 |
2485-2494 |
Negative_regulation |
denotes |
deficient |
| T5699 |
2501-2517 |
Positive_regulation |
denotes |
Stimulus-induced |
| T5700 |
2501-2517 |
Positive_regulation |
denotes |
Stimulus-induced |
| T5691 |
2518-2533 |
Phosphorylation |
denotes |
phosphorylation |
| T5692 |
2518-2533 |
Phosphorylation |
denotes |
phosphorylation |
| T5685 |
2541-2551 |
Protein |
denotes |
IκB kinase |
| T5686 |
2553-2559 |
Protein |
denotes |
IKK1/2 |
| T5687 |
2585-2590 |
Protein |
denotes |
NF-κB |
| T5701 |
2602-2610 |
Positive_regulation |
denotes |
allowing |
| T5702 |
2602-2610 |
Positive_regulation |
denotes |
allowing |
| T5703 |
2602-2610 |
Positive_regulation |
denotes |
allowing |
| T5693 |
2611-2626 |
Phosphorylation |
denotes |
phosphorylation |
| T5694 |
2611-2626 |
Phosphorylation |
denotes |
phosphorylation |
| T5704 |
2631-2650 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5705 |
2631-2650 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5706 |
2631-2650 |
Positive_regulation |
denotes |
proteasome-mediated |
| T5695 |
2651-2662 |
Protein_catabolism |
denotes |
degradation |
| T5696 |
2651-2662 |
Protein_catabolism |
denotes |
degradation |
| T5697 |
2651-2662 |
Protein_catabolism |
denotes |
degradation |
| T5688 |
2670-2675 |
Protein |
denotes |
NF-κB |
| T5689 |
2686-2690 |
Protein |
denotes |
IκBα |
| T5707 |
2694-2701 |
Localization |
denotes |
release |
| T5690 |
2706-2733 |
Protein |
denotes |
NF-κB transcription factors |
| T5698 |
2743-2750 |
Entity |
denotes |
nucleus |
| T5716 |
2948-2957 |
Negative_regulation |
denotes |
exhibited |
| T5717 |
2948-2957 |
Negative_regulation |
denotes |
exhibited |
| T5711 |
2966-2972 |
Positive_regulation |
denotes |
levels |
| T5712 |
2966-2972 |
Positive_regulation |
denotes |
levels |
| T5718 |
2966-2972 |
Positive_regulation |
denotes |
levels |
| T5719 |
2966-2972 |
Positive_regulation |
denotes |
levels |
| T5720 |
2966-2972 |
Positive_regulation |
denotes |
levels |
| T5708 |
2976-2980 |
Protein |
denotes |
TBK1 |
| T5709 |
2982-2988 |
Protein |
denotes |
ERK1/2 |
| T5710 |
2994-2997 |
Protein |
denotes |
p38 |
| T5713 |
2998-3013 |
Phosphorylation |
denotes |
phosphorylation |
| T5714 |
2998-3013 |
Phosphorylation |
denotes |
phosphorylation |
| T5715 |
2998-3013 |
Phosphorylation |
denotes |
phosphorylation |
| T5727 |
3077-3084 |
Negative_regulation |
denotes |
absence |
| T5721 |
3099-3119 |
Protein |
denotes |
SHARPIN decreased NF |
| T5722 |
3120-3122 |
Protein |
denotes |
κB |
| T5728 |
3123-3133 |
Positive_regulation |
denotes |
activation |
| T5729 |
3146-3152 |
Regulation |
denotes |
affect |
| T5730 |
3146-3152 |
Regulation |
denotes |
affect |
| T5731 |
3146-3152 |
Regulation |
denotes |
affect |
| T5723 |
3153-3157 |
Protein |
denotes |
TBK1 |
| T5724 |
3158-3162 |
Protein |
denotes |
IRF3 |
| T5725 |
3164-3168 |
Protein |
denotes |
ERK1 |
| T5726 |
3176-3179 |
Protein |
denotes |
p38 |
| T15304 |
3243-3253 |
Negative_regulation |
denotes |
Inhibition |
| T15303 |
3257-3262 |
Protein |
denotes |
NF-κB |
| T15305 |
3544-3549 |
Protein |
denotes |
NF-κB |
| T15306 |
3551-3555 |
Protein |
denotes |
TBK1 |
| T15307 |
3556-3560 |
Protein |
denotes |
IRF3 |
| T15308 |
3562-3566 |
Protein |
denotes |
ERK1 |
| T15309 |
3574-3577 |
Protein |
denotes |
p38 |
| T15310 |
3598-3602 |
Protein |
denotes |
Beta |
| T15311 |
3603-3608 |
Protein |
denotes |
actin |
| T15315 |
3651-3657 |
Gene_expression |
denotes |
levels |
| T15312 |
3674-3680 |
Protein |
denotes |
p-IκBα |
| T15313 |
3739-3745 |
Protein |
denotes |
ImageJ |
| T15314 |
3747-3750 |
Protein |
denotes |
NIH |
| R12530 |
T14953 |
T14956 |
themeOf |
TLR4,expression |
| R12531 |
T14954 |
T14957 |
themeOf |
MD2,expression |
| R12532 |
T14955 |
T14960 |
themeOf |
IL10,secretion |
| R12533 |
T14956 |
T14958 |
themeOf |
expression,decreased |
| R12534 |
T14957 |
T14959 |
themeOf |
expression,decreased |
| R12535 |
T14960 |
T14961 |
themeOf |
secretion,decreased |
| R12536 |
T14967 |
T14968 |
themeOf |
A20,production |
| R12792 |
T15303 |
T15304 |
themeOf |
NF-κB,Inhibition |
| R12793 |
T15312 |
T15315 |
themeOf |
p-IκBα,levels |
| R4542 |
T5634 |
T5635 |
themeOf |
TLR,expression |
| R4543 |
T5635 |
T5636 |
themeOf |
expression,increased |
| R4544 |
T5637 |
T5643 |
themeOf |
LPS receptor,expression |
| R4545 |
T5638 |
T5644 |
themeOf |
TLR4,expression |
| R4546 |
T5645 |
T5648 |
themeOf |
CD14,expression |
| R4547 |
T5646 |
T5649 |
themeOf |
TLR4,expression |
| R4548 |
T5647 |
T5650 |
themeOf |
MD2,expression |
| R4549 |
T5651 |
T5653 |
themeOf |
cytokines IL10,secretion |
| R4550 |
T5651 |
T5655 |
causeOf |
cytokines IL10,inhibit |
| R4551 |
T5652 |
T5654 |
themeOf |
IL12,secretion |
| R4552 |
T5654 |
T5655 |
themeOf |
secretion,inhibit |
| R4553 |
T5656 |
T5659 |
themeOf |
IL10,stimulated |
| R4554 |
T5657 |
T5661 |
causeOf |
IL10,responsible |
| R4555 |
T5658 |
T5660 |
themeOf |
IL12P70,secretion |
| R4556 |
T5660 |
T5661 |
themeOf |
secretion,responsible |
| R4557 |
T5660 |
T5662 |
themeOf |
secretion,decreased |
| R4558 |
T5663 |
T5664 |
themeOf |
TLR,expression |
| R4559 |
T5664 |
T5665 |
themeOf |
expression,Increased |
| R4560 |
T5667 |
T5668 |
themeOf |
A20,overexpression |
| R4561 |
T5668 |
T5669 |
themeOf |
overexpression,overexpression |
| R4562 |
T5668 |
T5670 |
themeOf |
overexpression,ruling |
| R4563 |
T5669 |
T5671 |
themeOf |
overexpression,ruling |
| R4564 |
T5673 |
T5676 |
themeOf |
NF-κB,regulated |
| R4565 |
T5674 |
T5677 |
themeOf |
TBK1,regulated |
| R4566 |
T5675 |
T5678 |
themeOf |
IRF3,regulated |
| R4567 |
T5683 |
T5684 |
themeOf |
Sharpin,deficient |
| R4568 |
T5685 |
T5691 |
themeOf |
IκB kinase,phosphorylation |
| R4569 |
T5686 |
T5692 |
themeOf |
IKK1/2,phosphorylation |
| R4570 |
T5686 |
T5695 |
themeOf |
IKK1/2,degradation |
| R4571 |
T5688 |
T5693 |
themeOf |
NF-κB,phosphorylation |
| R4572 |
T5688 |
T5696 |
themeOf |
NF-κB,degradation |
| R4573 |
T5689 |
T5694 |
themeOf |
IκBα,phosphorylation |
| R4574 |
T5689 |
T5697 |
themeOf |
IκBα,degradation |
| R4575 |
T5690 |
T5707 |
themeOf |
NF-κB transcription factors,release |
| R4576 |
T5691 |
T5699 |
themeOf |
phosphorylation,Stimulus-induced |
| R4577 |
T5692 |
T5700 |
themeOf |
phosphorylation,Stimulus-induced |
| R4578 |
T5695 |
T5701 |
themeOf |
degradation,allowing |
| R4579 |
T5695 |
T5704 |
themeOf |
degradation,proteasome-mediated |
| R4580 |
T5696 |
T5702 |
themeOf |
degradation,allowing |
| R4581 |
T5696 |
T5705 |
themeOf |
degradation,proteasome-mediated |
| R4582 |
T5697 |
T5703 |
themeOf |
degradation,allowing |
| R4583 |
T5697 |
T5706 |
themeOf |
degradation,proteasome-mediated |
| R4584 |
T5698 |
T5707 |
locationOf |
nucleus,release |
| R4585 |
T5708 |
T5711 |
themeOf |
TBK1,levels |
| R4586 |
T5708 |
T5713 |
themeOf |
TBK1,phosphorylation |
| R4587 |
T5709 |
T5712 |
themeOf |
ERK1/2,levels |
| R4588 |
T5709 |
T5714 |
themeOf |
ERK1/2,phosphorylation |
| R4589 |
T5710 |
T5715 |
themeOf |
p38,phosphorylation |
| R4590 |
T5711 |
T5716 |
themeOf |
levels,exhibited |
| R4591 |
T5712 |
T5717 |
themeOf |
levels,exhibited |
| R4592 |
T5713 |
T5718 |
themeOf |
phosphorylation,levels |
| R4593 |
T5714 |
T5719 |
themeOf |
phosphorylation,levels |
| R4594 |
T5715 |
T5720 |
themeOf |
phosphorylation,levels |
| R4595 |
T5721 |
T5727 |
themeOf |
SHARPIN decreased NF,absence |
| R4596 |
T5722 |
T5728 |
themeOf |
κB,activation |
| R4597 |
T5723 |
T5729 |
themeOf |
TBK1,affect |
| R4598 |
T5724 |
T5730 |
themeOf |
IRF3,affect |
| R4599 |
T5725 |
T5731 |
themeOf |
ERK1,affect |
| R4600 |
T5727 |
T5729 |
causeOf |
absence,affect |
| R4601 |
T5727 |
T5730 |
causeOf |
absence,affect |
| R4602 |
T5727 |
T5731 |
causeOf |
absence,affect |
