Id |
Subject |
Object |
Predicate |
Lexical cue |
T2235 |
85-95 |
Positive_regulation |
denotes |
initiating |
T2236 |
85-95 |
Positive_regulation |
denotes |
initiating |
T2233 |
96-111 |
Phosphorylation |
denotes |
phosphorylation |
T2234 |
116-126 |
Positive_regulation |
denotes |
activation |
T2232 |
130-199 |
Protein |
denotes |
multiple host intracellular protein kinases and transcription factors |
T2240 |
459-468 |
Regulation |
denotes |
regulator |
T2241 |
459-468 |
Regulation |
denotes |
regulator |
T2237 |
472-495 |
Protein |
denotes |
tumor necrosis factor-α |
T2238 |
497-502 |
Protein |
denotes |
TNF-α |
T2239 |
517-522 |
Protein |
denotes |
TNF-α |
T2242 |
625-630 |
Protein |
denotes |
TNF-α |
T2246 |
631-640 |
Gene_expression |
denotes |
synthesis |
T2247 |
648-658 |
Negative_regulation |
denotes |
attenuated |
T2245 |
686-703 |
Protein |
denotes |
phosphodiesterase |
T2243 |
705-708 |
Protein |
denotes |
PDE |
T2248 |
710-720 |
Negative_regulation |
denotes |
inhibition |
T2249 |
710-720 |
Negative_regulation |
denotes |
inhibition |
T2251 |
865-879 |
Negative_regulation |
denotes |
downregulation |
T2244 |
883-888 |
Protein |
denotes |
TNF-α |
T2250 |
889-899 |
Gene_expression |
denotes |
production |
T2265 |
1015-1022 |
Positive_regulation |
denotes |
results |
T2257 |
1044-1056 |
Positive_regulation |
denotes |
accumulation |
T2258 |
1138-1148 |
Positive_regulation |
denotes |
activation |
T2252 |
1152-1168 |
Protein |
denotes |
Protein kinase A |
T2253 |
1170-1173 |
Protein |
denotes |
PKA |
T2254 |
1177-1180 |
Protein |
denotes |
PKA |
T2259 |
1181-1191 |
Positive_regulation |
denotes |
activation |
T2260 |
1181-1191 |
Positive_regulation |
denotes |
activation |
T2261 |
1197-1202 |
Positive_regulation |
denotes |
leads |
T2262 |
1197-1202 |
Positive_regulation |
denotes |
leads |
T2263 |
1210-1225 |
Phosphorylation |
denotes |
phosphorylation |
T2264 |
1210-1225 |
Phosphorylation |
denotes |
phosphorylation |
T2255 |
1254-1291 |
Protein |
denotes |
cAMP-response element binding protein |
T2256 |
1293-1297 |
Protein |
denotes |
CREB |
T2266 |
1668-1671 |
Protein |
denotes |
PKA |
T2269 |
1726-1736 |
Positive_regulation |
denotes |
activation |
T2270 |
1726-1736 |
Positive_regulation |
denotes |
activation |
T2267 |
1744-1782 |
Protein |
denotes |
transcription factor nuclear factor-κB |
T2268 |
1784-1789 |
Protein |
denotes |
NF-κB |
T2275 |
1927-1934 |
Negative_regulation |
denotes |
inhibit |
T2276 |
1927-1934 |
Negative_regulation |
denotes |
inhibit |
T2271 |
1935-1940 |
Protein |
denotes |
NF-κB |
T2273 |
1973-1986 |
Transcription |
denotes |
transcription |
T2274 |
1973-1986 |
Transcription |
denotes |
transcription |
T2272 |
2008-2013 |
Protein |
denotes |
TNF-α |
T2277 |
2082-2085 |
Protein |
denotes |
PDE |
T2279 |
2086-2096 |
Negative_regulation |
denotes |
inhibition |
T2281 |
2097-2111 |
Negative_regulation |
denotes |
down-regulates |
T2278 |
2112-2117 |
Protein |
denotes |
TNF-α |
T2280 |
2118-2128 |
Gene_expression |
denotes |
production |
T2292 |
2177-2187 |
Negative_regulation |
denotes |
inhibition |
T2282 |
2191-2196 |
Protein |
denotes |
NF-κB |
T2289 |
2201-2208 |
Binding |
denotes |
binding |
T2283 |
2237-2242 |
Protein |
denotes |
NF-κB |
T2284 |
2279-2283 |
Protein |
denotes |
CREB |
T2290 |
2284-2294 |
Positive_regulation |
denotes |
activation |
T2291 |
2300-2311 |
Binding |
denotes |
competition |
T2285 |
2320-2325 |
Protein |
denotes |
NF-κB |
T2286 |
2330-2334 |
Protein |
denotes |
CREB |
T2287 |
2368-2388 |
Protein |
denotes |
CREB binding protein |
T2288 |
2390-2393 |
Protein |
denotes |
CBP |
T2294 |
2462-2472 |
Positive_regulation |
denotes |
activation |
T2293 |
2476-2479 |
Protein |
denotes |
PKA |
T2295 |
2651-2656 |
Protein |
denotes |
NF-κB |
T2296 |
2661-2665 |
Protein |
denotes |
CREB |
T2297 |
2666-2676 |
Positive_regulation |
denotes |
activation |
T2298 |
2666-2676 |
Positive_regulation |
denotes |
activation |
T2302 |
2776-2780 |
Positive_regulation |
denotes |
role |
T2299 |
2784-2787 |
Protein |
denotes |
PKA |
T2303 |
2791-2802 |
Positive_regulation |
denotes |
LPS-induced |
T2300 |
2803-2808 |
Protein |
denotes |
TNF-α |
T2301 |
2809-2819 |
Gene_expression |
denotes |
production |
R1748 |
T2232 |
T2233 |
themeOf |
multiple host intracellular protein kinases and transcription factors,phosphorylation |
R1749 |
T2233 |
T2234 |
themeOf |
phosphorylation,activation |
R1750 |
T2233 |
T2235 |
themeOf |
phosphorylation,initiating |
R1751 |
T2234 |
T2236 |
themeOf |
activation,initiating |
R1752 |
T2237 |
T2240 |
themeOf |
tumor necrosis factor-α,regulator |
R1753 |
T2238 |
T2241 |
themeOf |
TNF-α,regulator |
R1754 |
T2242 |
T2246 |
themeOf |
TNF-α,synthesis |
R1755 |
T2243 |
T2248 |
themeOf |
PDE,inhibition |
R1756 |
T2244 |
T2250 |
themeOf |
TNF-α,production |
R1757 |
T2245 |
T2249 |
themeOf |
phosphodiesterase,inhibition |
R1758 |
T2246 |
T2247 |
themeOf |
synthesis,attenuated |
R1759 |
T2250 |
T2251 |
themeOf |
production,downregulation |
R1760 |
T2280 |
T2281 |
themeOf |
production,down-regulates |
R1761 |
T2252 |
T2257 |
themeOf |
Protein kinase A,accumulation |
R1762 |
T2282 |
T2289 |
themeOf |
NF-κB,binding |
R1763 |
T2253 |
T2259 |
themeOf |
PKA,activation |
R1764 |
T2284 |
T2290 |
themeOf |
CREB,activation |
R1765 |
T2285 |
T2291 |
themeOf |
NF-κB,competition |
R1766 |
T2286 |
T2291 |
themeOf |
CREB,competition |
R1767 |
T2289 |
T2292 |
themeOf |
binding,inhibition |
R1768 |
T2254 |
T2260 |
themeOf |
PKA,activation |
R1769 |
T2255 |
T2263 |
themeOf |
cAMP-response element binding protein,phosphorylation |
R1770 |
T2293 |
T2294 |
themeOf |
PKA,activation |
R1771 |
T2256 |
T2264 |
themeOf |
CREB,phosphorylation |
R1772 |
T2295 |
T2297 |
themeOf |
NF-κB,activation |
R1773 |
T2296 |
T2298 |
themeOf |
CREB,activation |
R1774 |
T2257 |
T2258 |
themeOf |
accumulation,activation |
R1775 |
T2258 |
T2265 |
themeOf |
activation,results |
R1776 |
T2299 |
T2302 |
causeOf |
PKA,role |
R1777 |
T2300 |
T2301 |
themeOf |
TNF-α,production |
R1778 |
T2301 |
T2302 |
themeOf |
production,role |
R1779 |
T2301 |
T2303 |
themeOf |
production,LPS-induced |
R1780 |
T2259 |
T2261 |
themeOf |
activation,leads |
R1781 |
T2260 |
T2262 |
themeOf |
activation,leads |
R1782 |
T2267 |
T2269 |
themeOf |
transcription factor nuclear factor-κB,activation |
R1783 |
T2268 |
T2270 |
themeOf |
NF-κB,activation |
R1784 |
T2271 |
T2273 |
themeOf |
NF-κB,transcription |
R1785 |
T2272 |
T2274 |
themeOf |
TNF-α,transcription |
R1787 |
T2272 |
T2275 |
causeOf |
TNF-α,inhibit |
R1788 |
T2272 |
T2276 |
causeOf |
TNF-α,inhibit |
R1789 |
T2273 |
T2275 |
themeOf |
transcription,inhibit |
R1791 |
T2274 |
T2276 |
themeOf |
transcription,inhibit |
R1792 |
T2277 |
T2279 |
themeOf |
PDE,inhibition |
R1794 |
T2278 |
T2280 |
themeOf |
TNF-α,production |
R1796 |
T2279 |
T2281 |
causeOf |
inhibition,down-regulates |