PMC:2626671 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T624 0-24 Protein denotes Runx3 and T-box proteins
T625 124-128 Protein denotes CD8+
T626 338-346 Protein denotes perforin
T627 561-588 Protein denotes T-box transcription factors
T628 632-642 Protein denotes interferon
T629 644-647 Protein denotes IFN
T630 729-755 Protein denotes transcription factor Runx3
T631 780-785 Protein denotes Runx3
T638 786-795 Regulation denotes regulates
T639 786-795 Regulation denotes regulates
T640 786-795 Regulation denotes regulates
T635 824-834 Gene_expression denotes expression
T636 824-834 Gene_expression denotes expression
T637 824-834 Gene_expression denotes expression
T632 890-895 Protein denotes IFN-γ
T633 897-905 Protein denotes perforin
T634 911-921 Protein denotes granzyme B
T641 1004-1009 Protein denotes Runx3
T642 1053-1080 Protein denotes T-box transcription factors
T3216 4449-4453 Protein denotes CD8+
T3217 4484-4488 Protein denotes CD8+
T3218 4502-4505 Protein denotes P14
T3219 4554-4562 Protein denotes anti-CD3
T3220 4567-4576 Protein denotes anti-CD28
T3221 4617-4629 Protein denotes Gp33 peptide
T3222 4681-4703 Protein denotes recombinant human IL-2
T3223 4705-4711 Protein denotes rhIL-2
T3224 4806-4810 Protein denotes CD8+
T3225 5106-5109 Protein denotes CD3
T3226 5115-5119 Protein denotes CD28
T3227 5257-5261 Protein denotes CD8+
T3228 5429-5433 Protein denotes CD8+
T4534 5478-5488 Gene_expression denotes expression
T4535 5478-5488 Gene_expression denotes expression
T4532 5501-5509 Protein denotes perforin
T4533 5514-5524 Protein denotes granzyme B
T4536 5674-5678 Protein denotes CD8+
T4539 5739-5749 Gene_expression denotes expression
T4540 5739-5749 Gene_expression denotes expression
T4537 5753-5766 Protein denotes perforin mRNA
T4538 5778-5786 Protein denotes perforin
T4541 5855-5863 Protein denotes perforin
T4542 5865-5869 Protein denotes Prf1
T4543 5876-5886 Transcription denotes expression
T4544 5876-5886 Transcription denotes expression
T4545 5895-5903 Positive_regulation denotes increase
T4546 5895-5903 Positive_regulation denotes increase
T4547 5951-5959 Negative_regulation denotes decrease
T4548 5951-5959 Negative_regulation denotes decrease
T4549 5989-6001 Positive_regulation denotes reexpression
T4550 5989-6001 Positive_regulation denotes reexpression
T4551 6051-6061 Protein denotes granzyme B
T4552 6063-6067 Protein denotes Gzmb
T4554 6085-6097 Transcription denotes undetectable
T4555 6085-6097 Transcription denotes undetectable
T4556 6132-6144 Positive_regulation denotes up-regulated
T4557 6132-6144 Positive_regulation denotes up-regulated
T4558 6176-6185 Positive_regulation denotes increased
T4559 6176-6185 Positive_regulation denotes increased
T4553 6242-6260 Protein denotes granzyme B protein
T4560 6265-6274 Gene_expression denotes expressed
T4561 6297-6301 Positive_regulation denotes high
T4565 6373-6382 Gene_expression denotes expressed
T4566 6373-6382 Gene_expression denotes expressed
T4562 6397-6402 Protein denotes IFN-γ
T4563 6407-6410 Protein denotes TNF
T4568 6457-6466 Positive_regulation denotes increased
T4567 6516-6519 Gene_expression denotes see
T4564 6525-6533 Protein denotes Fig. 2 A
T19043 6581-6585 Protein denotes CD8+
T19044 6626-6630 Protein denotes Prf1
T19045 6632-6636 Protein denotes Gzmb
T19046 6638-6643 Protein denotes Tbx21
T19047 6657-6667 Protein denotes Eomes mRNA
T19049 6668-6678 Gene_expression denotes expression
T19050 6668-6678 Gene_expression denotes expression
T19051 6668-6678 Gene_expression denotes expression
T19052 6668-6678 Gene_expression denotes expression
T19048 6698-6701 Protein denotes P14
T19053 6961-6964 Protein denotes P14
T19057 7126-7134 Gene_expression denotes staining
T19058 7126-7134 Gene_expression denotes staining
T19059 7126-7134 Gene_expression denotes staining
T19054 7139-7149 Protein denotes granzyme B
T19055 7151-7156 Protein denotes IFN-γ
T19056 7162-7165 Protein denotes TNF
T19060 7357-7360 Protein denotes P14
T19061 7421-7436 Protein denotes μM Gp33 peptide
T19062 7528-7531 Protein denotes CD8
T4569 8007-8010 Protein denotes TCR
T4571 8254-8261 Gene_expression denotes express
T4570 8294-8302 Protein denotes perforin
T4572 8744-8748 Protein denotes TCRs
T4573 8788-8798 Protein denotes granzyme B
T4576 8799-8809 Gene_expression denotes expression
T4574 8886-8894 Protein denotes perforin
T4577 8895-8905 Gene_expression denotes expression
T4578 8933-8940 Positive_regulation denotes induced
T4575 8988-8992 Protein denotes IL-2
T5868 9273-9283 Regulation denotes regulation
T5869 9273-9283 Regulation denotes regulation
T5866 9384-9388 Protein denotes Prf1
T5867 9393-9397 Protein denotes GzmB
T5870 9571-9575 Protein denotes CD8+
T5871 9616-9619 Protein denotes TCR
T5872 9841-9845 Protein denotes CD8+
T5873 9859-9862 Protein denotes TCR
T5875 9900-9906 Regulation denotes effect
T5874 9914-9924 Gene_expression denotes expression
T5877 9960-9969 Positive_regulation denotes induction
T5876 9973-9983 Protein denotes Eomes mRNA
T5884 10083-10091 Positive_regulation denotes preceded
T5881 10096-10106 Gene_expression denotes expression
T5878 10110-10119 Protein denotes GzmB mRNA
T5879 10132-10142 Protein denotes Eomes mRNA
T5882 10160-10169 Gene_expression denotes expressed
T5883 10188-10200 Gene_expression denotes reexpression
T5880 10204-10217 Protein denotes perforin mRNA
T5889 10446-10454 Positive_regulation denotes required
T5885 10465-10470 Protein denotes IFN-γ
T5887 10471-10481 Gene_expression denotes production
T5891 10578-10588 Positive_regulation denotes contribute
T5890 10602-10609 Regulation denotes control
T5886 10613-10621 Protein denotes perforin
T5888 10622-10632 Gene_expression denotes expression
T5892 10688-10691 Protein denotes TCR
T5896 10700-10706 Positive_regulation denotes induce
T5897 10728-10735 Positive_regulation denotes induces
T5893 10736-10741 Protein denotes IFN-γ
T5894 10844-10848 Protein denotes IL-2
T5899 10853-10862 Positive_regulation denotes activates
T5895 10863-10871 Protein denotes perforin
T5898 10872-10882 Gene_expression denotes expression
T7318 10885-10893 Protein denotes Perforin
T7319 10898-10908 Protein denotes granzyme B
T7320 10909-10919 Gene_expression denotes expression
T7321 10909-10919 Gene_expression denotes expression
T7322 10940-10949 Regulation denotes regulated
T7323 10940-10949 Regulation denotes regulated
T7324 10940-10949 Regulation denotes regulated
T7331 11038-11048 Gene_expression denotes expression
T7332 11038-11048 Gene_expression denotes expression
T7333 11038-11048 Gene_expression denotes expression
T7325 11052-11057 Protein denotes IFN-γ
T7326 11059-11067 Protein denotes perforin
T7327 11073-11083 Protein denotes granzyme B
T7328 11087-11091 Protein denotes CD8+
T7329 11105-11107 Protein denotes WT
T7330 11112-11117 Protein denotes Tbx21
T7334 11125-11135 Negative_regulation denotes -deficient
T7335 11125-11135 Negative_regulation denotes -deficient
T7336 11179-11182 Protein denotes CD8
T7338 11192-11200 Gene_expression denotes produced
T7337 11201-11206 Protein denotes IFN-γ
T7339 11332-11336 Protein denotes CD8+
T7342 11597-11603 Negative_regulation denotes defect
T7340 11607-11620 Protein denotes perforin mRNA
T7341 11621-11631 Gene_expression denotes expression
T7346 11701-11710 Negative_regulation denotes reduction
T7343 11714-11723 Protein denotes GzmB mRNA
T7349 11817-11825 Negative_regulation denotes decrease
T7350 11817-11825 Negative_regulation denotes decrease
T7347 11829-11839 Gene_expression denotes expression
T7348 11829-11839 Gene_expression denotes expression
T7344 11843-11861 Protein denotes granzyme B protein
T7345 11863-11866 Protein denotes Fig
T20028 11884-11894 Regulation denotes Regulation
T20029 11884-11894 Regulation denotes Regulation
T20023 11898-11906 Protein denotes perforin
T20024 11908-11918 Protein denotes granzyme B
T20025 11924-11929 Protein denotes IFN-γ
T20026 11930-11940 Gene_expression denotes expression
T20027 11930-11940 Gene_expression denotes expression
T20030 11989-11994 Protein denotes IFN-γ
T20033 11995-12005 Gene_expression denotes expression
T20034 11995-12005 Gene_expression denotes expression
T20035 11995-12005 Gene_expression denotes expression
T20031 12009-12011 Protein denotes WT
T20032 12013-12018 Protein denotes Tbx21
T20036 12069-12073 Protein denotes CD8+
T20037 12183-12188 Protein denotes IFN-γ
T20038 12189-12199 Gene_expression denotes expression
T20039 12271-12276 Protein denotes IFN-γ
T20040 12315-12319 Protein denotes Prf1
T20041 12324-12333 Protein denotes GzmB mRNA
T20045 12334-12344 Gene_expression denotes expression
T20046 12334-12344 Gene_expression denotes expression
T20042 12370-12373 Protein denotes CD8
T20047 12460-12470 Gene_expression denotes expressing
T20048 12460-12470 Gene_expression denotes expressing
T20043 12477-12481 Protein denotes VP16
T20044 12483-12490 Protein denotes Eo-VP16
T20049 12707-12717 Protein denotes Granzyme B
T20050 12722-12727 Protein denotes IFN-γ
T20053 12728-12738 Gene_expression denotes expression
T20054 12728-12738 Gene_expression denotes expression
T20051 12742-12747 Protein denotes Tbx21
T20052 12755-12760 Protein denotes Tbx21
T20055 12839-12844 Protein denotes IFN-γ
T20057 12845-12855 Gene_expression denotes production
T20056 12881-12888 Protein denotes Eo-VP16
T20058 13024-13034 Protein denotes GFP+ IFN-γ
T7351 13153-13158 Protein denotes Eomes
T7352 13180-13184 Protein denotes CD8+
T7353 13198-13200 Protein denotes WT
T7354 13205-13210 Protein denotes Tbx21
T7355 13440-13444 Protein denotes VP16
T7359 13480-13489 Positive_regulation denotes increased
T7356 13490-13498 Protein denotes perforin
T7358 13499-13509 Gene_expression denotes expression
T7357 13541-13544 Protein denotes CD8
T7360 13601-13608 Protein denotes Eo-VP16
T7364 13632-13638 Negative_regulation denotes defect
T7361 13642-13647 Protein denotes IFN-γ
T7363 13648-13658 Gene_expression denotes production
T7362 13687-13690 Protein denotes CD8
T7365 13721-13728 Protein denotes Eo-VP16
T7371 13737-13743 Positive_regulation denotes induce
T7366 13744-13753 Protein denotes GzmB mRNA
T7369 13754-13764 Gene_expression denotes expression
T7367 13842-13851 Protein denotes GzmB mRNA
T7370 13852-13862 Gene_expression denotes expression
T7368 13892-13899 Protein denotes Eo-VP16
T11239 13902-13907 Protein denotes Runx3
T11240 14013-14018 Protein denotes Runx3
T11245 14029-14038 Gene_expression denotes expressed
T11241 14053-14057 Protein denotes CD8+
T11242 14086-14097 Protein denotes T-bet-Runx3
T11243 14133-14137 Protein denotes CD4+
T11244 14176-14181 Protein denotes Runx3
T11246 14227-14230 Protein denotes CD8
T11247 14245-14250 Protein denotes Runx3
T11248 14304-14306 Protein denotes WT
T11249 14307-14312 Protein denotes Runx3
T11250 14425-14428 Protein denotes org
T11251 14429-14432 Protein denotes cgi
T11252 14477-14482 Protein denotes Runx3
T11253 14486-14489 Protein denotes CD8
T11258 14589-14599 Gene_expression denotes expression
T11259 14589-14599 Gene_expression denotes expression
T11260 14589-14599 Gene_expression denotes expression
T11261 14589-14599 Gene_expression denotes expression
T11254 14603-14611 Protein denotes perforin
T11255 14613-14623 Protein denotes granzyme B
T11256 14629-14634 Protein denotes IFN-γ
T11257 14636-14639 Protein denotes Fig
T11262 14671-14684 Protein denotes perforin mRNA
T11264 14697-14707 Gene_expression denotes expression
T11265 14725-14737 Positive_regulation denotes undetectable
T11263 14741-14746 Protein denotes Runx3
T11266 14797-14802 Protein denotes Runx3
T11267 14925-14930 Protein denotes Runx3
T11275 14935-14943 Positive_regulation denotes required
T11276 14935-14943 Positive_regulation denotes required
T11277 14935-14943 Positive_regulation denotes required
T11272 14956-14966 Gene_expression denotes production
T11273 14956-14966 Gene_expression denotes production
T11274 14956-14966 Gene_expression denotes production
T11268 14970-14975 Protein denotes IFN-γ
T11269 14985-14988 Protein denotes TNF
T11270 14992-14996 Protein denotes IL-2
T11271 15001-15005 Protein denotes CD8+
T20707 15071-15076 Protein denotes Runx3
T20708 15134-15139 Protein denotes Runx3
T20709 15159-15167 Protein denotes perforin
T20713 15168-15178 Gene_expression denotes expression
T20714 15168-15178 Gene_expression denotes expression
T20710 15182-15187 Protein denotes Runx3
T20711 15207-15210 Protein denotes CD8
T20712 15212-15216 Protein denotes SP T
T20715 15249-15254 Protein denotes Actin
T20716 15316-15325 Protein denotes Prf1 mRNA
T20719 15326-15336 Gene_expression denotes expression
T20717 15340-15345 Protein denotes Runx3
T20718 15365-15368 Protein denotes CD8
T20720 15404-15409 Protein denotes Actin
T20728 15445-15455 Gene_expression denotes Expression
T20729 15445-15455 Gene_expression denotes Expression
T20730 15445-15455 Gene_expression denotes Expression
T20731 15445-15455 Gene_expression denotes Expression
T20721 15459-15469 Protein denotes granzyme B
T20722 15471-15476 Protein denotes IFN-γ
T20723 15478-15481 Protein denotes TNF
T20724 15487-15491 Protein denotes IL-2
T20725 15525-15530 Protein denotes Runx3
T20726 15550-15553 Protein denotes CD8
T20727 15555-15559 Protein denotes SP T
T20732 15646-15652 Protein denotes WT GFP
T20736 15748-15755 Binding denotes binding
T20737 15748-15755 Binding denotes binding
T20738 15748-15755 Binding denotes binding
T20739 15748-15755 Binding denotes binding
T20733 15759-15775 Protein denotes endogenous Runx3
T20734 15780-15785 Protein denotes Eomes
T20735 15793-15803 Protein denotes Prf1 locus
T20740 16034-16038 Protein denotes CD8+
T20741 16124-16128 Protein denotes Prf1
T20742 16147-16157 Protein denotes Runx3 ChIP
T20743 16175-16185 Protein denotes Eomes ChIP
T11281 16322-16329 Positive_regulation denotes induces
T11278 16330-16335 Protein denotes Runx3
T11279 16359-16364 Protein denotes Runx3
T11280 16385-16407 Protein denotes IFN-γ and silence IL-4
T11282 16492-16497 Protein denotes Runx3
T11283 16606-16614 Protein denotes perforin
T11290 16615-16625 Gene_expression denotes expression
T11291 16644-16658 Positive_regulation denotes overexpression
T11292 16644-16658 Positive_regulation denotes overexpression
T11284 16662-16664 Protein denotes Eo
T11285 16665-16669 Protein denotes VP16
T11298 16710-16713 Positive_regulation denotes led
T11299 16710-16713 Positive_regulation denotes led
T11293 16720-16728 Positive_regulation denotes increase
T11300 16720-16728 Positive_regulation denotes increase
T11301 16720-16728 Positive_regulation denotes increase
T11286 16737-16745 Protein denotes perforin
T11287 16750-16755 Protein denotes IFN-γ
T11294 16756-16766 Gene_expression denotes expression
T11295 16756-16766 Gene_expression denotes expression
T11296 16877-16886 Regulation denotes involving
T11297 16877-16886 Regulation denotes involving
T11288 16913-16917 Protein denotes Runx
T11289 16922-16949 Protein denotes T-box transcription factors
T11302 16982-16987 Protein denotes Runx3
T11309 17060-17068 Regulation denotes regulate
T11310 17060-17068 Regulation denotes regulate
T11311 17060-17068 Regulation denotes regulate
T11306 17069-17082 Transcription denotes transcription
T11307 17069-17082 Transcription denotes transcription
T11308 17069-17082 Transcription denotes transcription
T11303 17111-17119 Protein denotes perforin
T11304 17121-17126 Protein denotes IFN-γ
T11305 17132-17142 Protein denotes granzyme B
T11312 17236-17241 Protein denotes Eomes
T11313 17246-17251 Protein denotes Runx3
T11319 17252-17257 Binding denotes bound
T11320 17252-17257 Binding denotes bound
T11321 17252-17257 Binding denotes bound
T11322 17252-17257 Binding denotes bound
T11323 17252-17257 Binding denotes bound
T11324 17252-17257 Binding denotes bound
T11318 17269-17276 Entity denotes regions
T11314 17284-17288 Protein denotes Prf1
T11315 17290-17294 Protein denotes Ifng
T11316 17300-17310 Protein denotes Gzmb genes
T11317 17312-17315 Protein denotes Fig
T11325 17401-17406 Protein denotes Runx3
T11333 17407-17412 Binding denotes bound
T11326 17420-17424 Protein denotes Prf1
T11327 17429-17433 Protein denotes Gzmb
T11328 17529-17533 Protein denotes Prf1
T11329 17572-17579 Protein denotes DNase I
T11330 17609-17613 Protein denotes Prf1
T11331 17633-17646 Protein denotes Ifng promoter
T11332 17719-17726 Protein denotes DNase I
T11344 17806-17811 Binding denotes bound
T11334 17829-17837 Protein denotes Prf1 TSS
T11340 17852-17860 Entity denotes enhancer
T11341 17927-17935 Entity denotes promoter
T11335 17943-17953 Protein denotes Il2rb gene
T11342 17970-17976 Binding denotes target
T11336 18030-18038 Protein denotes Ifng TSS
T11343 18048-18054 Binding denotes target
T11337 18058-18072 Protein denotes T-box proteins
T11338 18081-18084 Protein denotes Th1
T11339 18089-18093 Protein denotes CD8+
T11345 18140-18145 Protein denotes Runx3
T11354 18146-18156 Regulation denotes controlled
T11351 18161-18171 Gene_expression denotes expression
T11346 18175-18193 Protein denotes CTL effector genes
T11352 18242-18251 Gene_expression denotes expressed
T11353 18242-18251 Gene_expression denotes expressed
T11347 18252-18257 Protein denotes Runx3
T11348 18262-18269 Protein denotes Eo-VP16
T11349 18273-18277 Protein denotes CD8+
T11350 18291-18296 Protein denotes Runx3
T11355 18339-18343 Protein denotes CD8+
T11356 18408-18413 Protein denotes Runx3
T11357 18417-18420 Protein denotes CD8
T11358 18421-18424 Protein denotes CD4
T11359 18426-18428 Protein denotes SP
T11360 18433-18436 Protein denotes CD8
T11361 18437-18440 Protein denotes CD4
T11362 18494-18499 Protein denotes Runx3
T11363 18503-18506 Protein denotes CD8
T11364 18607-18612 Protein denotes Runx3
T11365 18616-18619 Protein denotes CD8
T11366 18634-18639 Protein denotes Runx3
T11371 18640-18648 Positive_regulation denotes restored
T11376 18640-18648 Positive_regulation denotes restored
T11377 18640-18648 Positive_regulation denotes restored
T11378 18640-18648 Positive_regulation denotes restored
T11379 18640-18648 Positive_regulation denotes restored
T11372 18649-18659 Gene_expression denotes expression
T11373 18649-18659 Gene_expression denotes expression
T11374 18649-18659 Gene_expression denotes expression
T11375 18649-18659 Gene_expression denotes expression
T11367 18680-18688 Protein denotes perforin
T11368 18690-18700 Protein denotes granzyme B
T11369 18706-18711 Protein denotes IFN-γ
T11370 18713-18716 Protein denotes Fig
T11380 18744-18749 Protein denotes Runx3
T11385 18783-18796 Positive_regulation denotes up-regulation
T11381 18800-18805 Protein denotes Runx1
T11386 18817-18827 Negative_regulation denotes suppressed
T11382 18853-18858 Protein denotes Runx3
T11383 18876-18881 Protein denotes Runx1
T11387 18897-18907 Negative_regulation denotes repression
T11384 18911-18916 Protein denotes Runx3
T11388 18927-18934 Protein denotes Eo-VP16
T11396 18943-18954 Positive_regulation denotes up-regulate
T11389 18955-18963 Protein denotes perforin
T11393 18964-18974 Gene_expression denotes expression
T11390 18993-18998 Protein denotes Runx3
T11398 19024-19032 Positive_regulation denotes restored
T11397 19049-19055 Positive_regulation denotes induce
T11391 19056-19061 Protein denotes IFN-γ
T11394 19062-19072 Gene_expression denotes expression
T11392 19078-19081 Protein denotes TCR
T11395 19082-19095 Positive_regulation denotes restimulation
T11399 19150-19158 Protein denotes perforin
T11402 19159-19169 Gene_expression denotes expression
T11400 19179-19184 Protein denotes Runx3
T11401 19189-19194 Protein denotes Eomes
T22048 19206-19211 Protein denotes Runx3
T22052 19212-19220 Regulation denotes controls
T22053 19212-19220 Regulation denotes controls
T22057 19212-19220 Regulation denotes controls
T22058 19212-19220 Regulation denotes controls
T22059 19212-19220 Regulation denotes controls
T22049 19228-19236 Protein denotes perforin
T22050 19238-19248 Protein denotes granzyme B
T22051 19254-19259 Protein denotes IFN-γ
T22054 19260-19270 Gene_expression denotes expression
T22055 19260-19270 Gene_expression denotes expression
T22056 19260-19270 Gene_expression denotes expression
T22060 19289-19294 Protein denotes Runx3
T22061 19301-19306 Protein denotes Runx3
T22062 19310-19313 Protein denotes CD8
T22063 19388-19405 Protein denotes IRES-GFP cassette
T22064 19407-19410 Protein denotes GFP
T22065 19429-19439 Protein denotes Eomes-VP16
T22066 19441-19443 Protein denotes Eo
T22067 19444-19448 Protein denotes VP16
T22068 19453-19456 Protein denotes Myc
T22069 19457-19462 Protein denotes Runx3
T22070 19464-19469 Protein denotes Runx3
T22074 19678-19692 Positive_regulation denotes Overexpression
T22075 19678-19692 Positive_regulation denotes Overexpression
T22071 19696-19701 Protein denotes Eomes
T22072 19702-19706 Protein denotes VP16
T22073 19830-19857 Protein denotes VP16 transactivation domain
T22078 19863-19873 Gene_expression denotes Expression
T22079 19863-19873 Gene_expression denotes Expression
T22076 19877-19887 Protein denotes granzyme B
T22077 19892-19897 Protein denotes IFN-γ
T22080 20120-20130 Protein denotes granzyme B
T22081 20131-20139 Gene_expression denotes staining
T22082 20235-20241 Protein denotes WT GFP
T22083 20381-20386 Protein denotes Runx3
T22084 20391-20404 Protein denotes T-box factors
T22085 20426-20429 Protein denotes TCR
T22088 20445-20454 Positive_regulation denotes essential
T22086 20465-20470 Protein denotes IFN-γ
T22087 20471-20481 Gene_expression denotes expression
T22089 20483-20488 Protein denotes Runx3
T22096 20492-20499 Gene_expression denotes present
T22090 20509-20513 Protein denotes CD8+
T22097 20526-20535 Negative_regulation denotes represses
T22091 20536-20541 Protein denotes Runx1
T22092 20554-20559 Protein denotes Eomes
T22093 20561-20569 Protein denotes perforin
T22094 20571-20581 Protein denotes granzyme B
T22095 20587-20592 Protein denotes IFN-γ
T22098 20593-20603 Gene_expression denotes expression
T22099 20593-20603 Gene_expression denotes expression
T22105 20615-20626 Regulation denotes participate
T22100 20646-20651 Protein denotes IFN-γ
T22103 20652-20662 Gene_expression denotes expression
T22101 20672-20677 Protein denotes Runx3
T22106 20721-20729 Positive_regulation denotes activate
T22102 20730-20738 Protein denotes perforin
T22104 20739-20749 Gene_expression denotes expression
T22111 20789-20795 Regulation denotes effect
T22112 20789-20795 Regulation denotes effect
T22107 20819-20828 Protein denotes Gzmb mRNA
T22108 20837-20855 Protein denotes granzyme B protein
T22109 20856-20866 Gene_expression denotes expression
T22110 20856-20866 Gene_expression denotes expression
T11409 20890-20896 Positive_regulation denotes defect
T11410 20890-20896 Positive_regulation denotes defect
T11403 20900-20908 Protein denotes perforin
T11404 20913-20923 Protein denotes granzyme B
T11407 20924-20934 Gene_expression denotes expression
T11408 20924-20934 Gene_expression denotes expression
T11405 20936-20941 Protein denotes Runx3
T11406 20945-20948 Protein denotes CD8
T11411 21040-21043 Protein denotes TCR
T11412 21055-21060 Protein denotes Runx3
T11413 21064-21067 Protein denotes CD8
T11414 21173-21177 Protein denotes CD8+
T11415 21214-21219 Protein denotes Runx3
T11421 21322-21332 Positive_regulation denotes activation
T11416 21340-21359 Protein denotes perforin/granzyme B
T11422 21373-21382 Negative_regulation denotes defective
T11417 21386-21391 Protein denotes Runx3
T11418 21395-21399 Protein denotes CD8+
T11419 21554-21557 Protein denotes Fas
T11420 21558-21561 Protein denotes Fas
T13673 21579-21584 Protein denotes Runx3
T13674 21733-21738 Protein denotes Runx3
T13675 21865-21870 Protein denotes Runx3
T13677 21874-21881 Gene_expression denotes present
T13676 21891-21895 Protein denotes CD8+
T13683 21931-21940 Negative_regulation denotes represses
T13678 21941-21946 Protein denotes Runx1
T13684 21978-21987 Positive_regulation denotes induction
T13685 21978-21987 Positive_regulation denotes induction
T13686 21978-21987 Positive_regulation denotes induction
T13687 21978-21987 Positive_regulation denotes induction
T13679 21991-21996 Protein denotes Eomes
T13680 21998-22008 Protein denotes granzyme B
T13681 22010-22018 Protein denotes perforin
T13682 22024-22029 Protein denotes IFN-γ
T13688 22031-22036 Protein denotes Runx3
T13690 22037-22042 Binding denotes binds
T13689 22046-22055 Entity denotes promoters
T13691 22227-22232 Protein denotes Runx1
T13692 22265-22270 Protein denotes Runx3
T13693 22286-22291 Protein denotes Runx3
T13700 22292-22303 Positive_regulation denotes contributed
T13701 22292-22303 Positive_regulation denotes contributed
T13702 22292-22303 Positive_regulation denotes contributed
T13697 22319-22329 Gene_expression denotes expression
T13698 22319-22329 Gene_expression denotes expression
T13699 22319-22329 Gene_expression denotes expression
T13694 22333-22336 Protein denotes TNF
T13695 22338-22342 Protein denotes IL-2
T13696 22348-22353 Protein denotes IFN-γ
T13703 22378-22381 Protein denotes TNF
T13704 22386-22390 Protein denotes IL-2
T13705 22412-22417 Protein denotes Runx3
T13708 22418-22426 Negative_regulation denotes subsides
T13706 22484-22489 Protein denotes Runx1
T13709 22500-22511 Negative_regulation denotes derepressed
T13707 22515-22520 Protein denotes Runx3
T13710 22542-22547 Protein denotes Runx3
T13713 22564-22572 Positive_regulation denotes required
T13711 22577-22582 Protein denotes IFN-γ
T13712 22583-22593 Gene_expression denotes expression
T13714 22820-22824 Protein denotes CD8+
T13718 22965-22971 Positive_regulation denotes needed
T13715 23001-23005 Protein denotes CD8+
T13717 23032-23039 Gene_expression denotes produce
T13716 23040-23045 Protein denotes IFN-γ
T13719 23174-23179 Protein denotes Runx3
T13722 23209-23218 Positive_regulation denotes promoting
T13721 23229-23239 Gene_expression denotes expression
T13720 23243-23248 Protein denotes IFN-γ
T13728 23304-23314 Positive_regulation denotes contribute
T13723 23318-23326 Protein denotes perforin
T13726 23327-23337 Gene_expression denotes expression
T13727 23369-23376 Positive_regulation denotes induces
T13724 23377-23387 Protein denotes granzyme B
T13725 23475-23502 Protein denotes T-box transcription factors
T13732 23613-23619 Positive_regulation denotes induce
T13733 23613-23619 Positive_regulation denotes induce
T13734 23613-23619 Positive_regulation denotes induce
T13729 23655-23659 Protein denotes Prf1
T13730 23664-23668 Protein denotes Gzmb
T13731 23670-23673 Protein denotes Fig
T13738 23783-23796 Positive_regulation denotes up-regulation
T13735 23810-23820 Protein denotes Eomes mRNA
T13739 23850-23863 Positive_regulation denotes up-regulation
T13740 23850-23863 Positive_regulation denotes up-regulation
T13736 23867-23871 Protein denotes Gzmb
T13737 23876-23885 Protein denotes Prf1 mRNA
T13747 23926-23930 Regulation denotes role
T13741 23934-23942 Protein denotes perforin
T13745 23943-23953 Gene_expression denotes expression
T13742 23988-23995 Protein denotes Eo-VP16
T13748 24004-24010 Regulation denotes affect
T13743 24011-24021 Protein denotes granzyme B
T13746 24022-24032 Gene_expression denotes expression
T13744 24063-24068 Protein denotes Runx3
T13749 24315-24320 Protein denotes Runx3
T13750 24342-24345 Protein denotes CD8
T13751 24402-24407 Protein denotes Runx3
T13754 24411-24417 Positive_regulation denotes induce
T13752 24418-24426 Protein denotes perforin
T13753 24427-24437 Gene_expression denotes expression
T13755 24529-24534 Protein denotes Runx3
T13759 24555-24562 Positive_regulation denotes induced
T13760 24555-24562 Positive_regulation denotes induced
T13756 24563-24582 Protein denotes T-box factors T-bet
T13757 24587-24592 Protein denotes Eomes
T13758 24597-24603 Protein denotes IL-2Rβ
T13761 24743-24748 Protein denotes Runx3
T13762 24781-24784 Protein denotes CD4
T13763 24889-24892 Protein denotes TCR
T13764 24905-24910 Protein denotes IFN-γ
T13765 24971-24975 Protein denotes CD8+
T13766 24997-25002 Protein denotes Runx3
T13768 25018-25024 Positive_regulation denotes induce
T13767 25029-25061 Protein denotes T-box transcription factor Eomes
T13769 25183-25194 Protein denotes Runx family
T14330 25423-25432 Protein denotes anti–IL-2
T14331 25434-25444 Protein denotes anti–IFN-γ
T14332 25446-25454 Protein denotes anti-TNF
T14333 25456-25471 Protein denotes anti–granzyme B
T14334 25473-25481 Protein denotes anti-CD8
T14335 25483-25492 Protein denotes anti-CD25
T14336 25503-25507 Protein denotes CD44
T14337 25509-25518 Protein denotes Anti-CD69
T14338 25620-25639 Protein denotes anti-Runx3 antibody
T14339 25644-25652 Gene_expression denotes produced
T14340 25830-25844 Protein denotes T-bet antibody
T14341 26044-26047 Protein denotes CD8
T14342 26085-26088 Protein denotes CD8
T14343 26178-26182 Protein denotes Gp33
T14893 26343-26347 Protein denotes CD8+
T14894 26357-26360 Protein denotes CD8
T14895 26396-26403 Protein denotes P14 TCR
T14896 26442-26447 Protein denotes Tbx21
T14897 26585-26589 Protein denotes CD8+
T14898 26603-26608 Protein denotes Runx3
T14899 26812-26826 Protein denotes Immune Disease
T14900 26926-26930 Protein denotes CD8+
T14901 27019-27027 Protein denotes anti-CD3
T14902 27029-27039 Protein denotes clone 2C11
T14903 27050-27054 Protein denotes CD28
T14904 27105-27121 Protein denotes anti–hamster IgG
T14905 27163-27166 Protein denotes TCR
T14906 27406-27412 Protein denotes rhIL-2
T16058 27428-27432 Protein denotes CD8+
T16059 27446-27451 Protein denotes Runx3
T16060 27461-27466 Protein denotes Runx3
T16062 27467-27476 Negative_regulation denotes deficient
T16064 27493-27500 Negative_regulation denotes silence
T16061 27501-27504 Protein denotes CD4
T16063 27505-27515 Gene_expression denotes expression
T16065 27603-27607 Protein denotes CD8+
T16066 27621-27629 Protein denotes Runx3 KO
T16067 27640-27643 Protein denotes CD8
T16068 27644-27647 Protein denotes CD4
T16069 27649-27651 Protein denotes SP
T16070 27655-27658 Protein denotes CD8
T16071 27659-27662 Protein denotes CD4
T16072 27733-27741 Protein denotes Runx3 KO
T16073 27786-27789 Protein denotes CD8
T16074 27790-27793 Protein denotes CD4
T16075 27852-27855 Protein denotes CD8
T16076 27856-27859 Protein denotes CD4
T16077 27909-27917 Protein denotes anti-CD3
T16078 27919-27928 Protein denotes anti-CD28
T16079 27967-27970 Protein denotes TCR
T16080 28058-28061 Protein denotes TCR
T16081 28087-28092 Protein denotes Runx3
T16082 28096-28099 Protein denotes CD8
T16083 28148-28151 Protein denotes CD4
T16084 28152-28162 Gene_expression denotes expression
T16085 28196-28201 Protein denotes Runx3
T16090 28292-28305 Positive_regulation denotes up-regulation
T16091 28292-28305 Positive_regulation denotes up-regulation
T16092 28292-28305 Positive_regulation denotes up-regulation
T16086 28309-28313 Protein denotes CD25
T16087 28318-28322 Protein denotes CD69
T16088 28324-28327 Protein denotes Fig
T16089 28329-28331 Protein denotes S1
T16097 28368-28379 Positive_regulation denotes up-regulate
T16093 28380-28384 Protein denotes CD25
T16094 28386-28391 Protein denotes Runx3
T16095 28395-28398 Protein denotes CD8
T16096 28421-28425 Protein denotes IL-2
T16104 28610-28618 Negative_regulation denotes silenced
T16098 28619-28622 Protein denotes CD4
T16102 28623-28633 Gene_expression denotes expression
T16099 28932-28937 Protein denotes Runx3
T16100 28941-28944 Protein denotes CD8
T16103 28964-28973 Gene_expression denotes coexpress
T16101 28974-28977 Protein denotes CD4
T16106 29033-29042 Gene_expression denotes presented
T16105 29046-29049 Protein denotes Fig
T16107 29051-29053 Protein denotes S2
T16108 29063-29071 Protein denotes Runx3 KO
T16109 29134-29139 Protein denotes Runx3
T16110 29140-29146 Protein denotes KO CD8
T16367 29211-29214 Protein denotes EL4
T16368 29260-29275 Protein denotes μM Gp33 peptide
T16369 29315-29318 Protein denotes P14
T16370 29501-29504 Protein denotes CD8
T16371 29505-29520 Protein denotes allophycocyanin
T16372 29608-29611 Protein denotes CD8
T16930 30388-30392 Protein denotes CD8+
T16931 30602-30605 Protein denotes TCR
T16932 30624-30627 Protein denotes CD8
T16933 30931-30936 Protein denotes Eomes
T16934 30937-30941 Protein denotes VP16
T17552 31782-31811 Protein denotes plus protease and phosphatase
T17553 32672-32679 Protein denotes RNase A
T17554 33363-33366 Protein denotes org
T17555 33367-33370 Protein denotes cgi
T18111 34389-34393 Protein denotes CD8+
T18274 35053-35056 Protein denotes Fig
T18275 35058-35060 Protein denotes S1
T18276 35102-35106 Protein denotes CD8+
T18277 35120-35125 Protein denotes Runx3
T18278 35135-35138 Protein denotes Fig
T18279 35180-35188 Protein denotes Runx3 WT
T18280 35288-35296 Protein denotes Table S1
T18281 35358-35361 Protein denotes org
T18282 35362-35365 Protein denotes cgi
R10737 T13675 T13677 themeOf Runx3,present
R10738 T13678 T13683 themeOf Runx1,represses
R10739 T13679 T13684 themeOf Eomes,induction
R10740 T13680 T13685 themeOf granzyme B,induction
R10741 T13681 T13686 themeOf perforin,induction
R10742 T13682 T13687 themeOf IFN-γ,induction
R10743 T13688 T13690 themeOf Runx3,binds
R10744 T13689 T13690 Site promoters,binds
R10745 T13693 T13700 causeOf Runx3,contributed
R10746 T13693 T13701 causeOf Runx3,contributed
R10747 T13693 T13702 causeOf Runx3,contributed
R10748 T13694 T13697 themeOf TNF,expression
R10749 T13695 T13698 themeOf IL-2,expression
R10750 T13696 T13699 themeOf IFN-γ,expression
R10751 T13697 T13700 themeOf expression,contributed
R10752 T13698 T13701 themeOf expression,contributed
R10753 T13699 T13702 themeOf expression,contributed
R10754 T13705 T13708 themeOf Runx3,subsides
R10755 T13706 T13709 themeOf Runx1,derepressed
R10756 T13710 T13713 causeOf Runx3,required
R10757 T13711 T13712 themeOf IFN-γ,expression
R10758 T13712 T13713 themeOf expression,required
R10759 T13716 T13717 themeOf IFN-γ,produce
R10760 T13717 T13718 themeOf produce,needed
R10761 T13720 T13721 themeOf IFN-γ,expression
R10762 T13721 T13722 themeOf expression,promoting
R10763 T13723 T13726 themeOf perforin,expression
R10764 T13724 T13727 themeOf granzyme B,induces
R10765 T13726 T13728 themeOf expression,contribute
R10766 T13729 T13732 themeOf Prf1,induce
R10767 T13730 T13733 themeOf Gzmb,induce
R10768 T13731 T13734 themeOf Fig,induce
R10769 T13735 T13738 themeOf Eomes mRNA,up-regulation
R10770 T13736 T13739 themeOf Gzmb,up-regulation
R10771 T13737 T13740 themeOf Prf1 mRNA,up-regulation
R10772 T13741 T13745 themeOf perforin,expression
R10773 T13742 T13748 causeOf Eo-VP16,affect
R10774 T13743 T13746 themeOf granzyme B,expression
R10775 T13745 T13747 themeOf expression,role
R10776 T13746 T13748 themeOf expression,affect
R10777 T13751 T13754 causeOf Runx3,induce
R10778 T13752 T13753 themeOf perforin,expression
R10779 T13753 T13754 themeOf expression,induce
R10780 T13756 T13759 themeOf T-box factors T-bet,induced
R10781 T13757 T13760 themeOf Eomes,induced
R10782 T13766 T13768 causeOf Runx3,induce
R10783 T13767 T13768 themeOf T-box transcription factor Eomes,induce
R11154 T14338 T14339 themeOf anti-Runx3 antibody,produced
R12339 T16060 T16062 themeOf Runx3,deficient
R12340 T16061 T16063 themeOf CD4,expression
R12341 T16062 T16064 causeOf deficient,silence
R12342 T16063 T16064 themeOf expression,silence
R12343 T16083 T16084 themeOf CD4,expression
R12344 T16086 T16090 themeOf CD25,up-regulation
R12345 T16087 T16091 themeOf CD69,up-regulation
R12346 T16089 T16092 themeOf S1,up-regulation
R12347 T16093 T16097 themeOf CD25,up-regulate
R12348 T16098 T16102 themeOf CD4,expression
R12349 T16101 T16103 themeOf CD4,coexpress
R12350 T16102 T16104 themeOf expression,silenced
R12351 T16105 T16106 themeOf Fig,presented
R14783 T19044 T19049 themeOf Prf1,expression
R14784 T19045 T19050 themeOf Gzmb,expression
R14785 T19046 T19051 themeOf Tbx21,expression
R14786 T19047 T19052 themeOf Eomes mRNA,expression
R14787 T19054 T19057 themeOf granzyme B,staining
R14788 T19055 T19058 themeOf IFN-γ,staining
R14789 T19056 T19059 themeOf TNF,staining
R15500 T20023 T20026 themeOf perforin,expression
R15501 T20025 T20027 themeOf IFN-γ,expression
R15502 T20026 T20028 themeOf expression,Regulation
R15503 T20027 T20029 themeOf expression,Regulation
R15504 T20030 T20033 themeOf IFN-γ,expression
R15505 T20031 T20034 themeOf WT,expression
R15506 T20032 T20035 themeOf Tbx21,expression
R15507 T20037 T20038 themeOf IFN-γ,expression
R15508 T20040 T20045 themeOf Prf1,expression
R15509 T20041 T20046 themeOf GzmB mRNA,expression
R15510 T20043 T20047 themeOf VP16,expressing
R15511 T20044 T20048 themeOf Eo-VP16,expressing
R15512 T20049 T20053 themeOf Granzyme B,expression
R15513 T20050 T20054 themeOf IFN-γ,expression
R15514 T20055 T20057 themeOf IFN-γ,production
R15867 T20708 T20713 themeOf Runx3,expression
R15868 T20709 T20714 themeOf perforin,expression
R15869 T20716 T20719 themeOf Prf1 mRNA,expression
R15870 T20721 T20728 themeOf granzyme B,Expression
R15871 T20722 T20729 themeOf IFN-γ,Expression
R15872 T20723 T20730 themeOf TNF,Expression
R15873 T20724 T20731 themeOf IL-2,Expression
R15874 T20733 T20736 themeOf endogenous Runx3,binding
R15875 T20733 T20738 themeOf endogenous Runx3,binding
R15876 T20734 T20737 themeOf Eomes,binding
R15877 T20734 T20739 themeOf Eomes,binding
R15878 T20735 T20738 themeOf Prf1 locus,binding
R15879 T20735 T20739 themeOf Prf1 locus,binding
R16902 T22048 T22052 causeOf Runx3,controls
R16903 T22048 T22053 causeOf Runx3,controls
R16904 T22048 T22057 causeOf Runx3,controls
R16905 T22048 T22058 causeOf Runx3,controls
R16906 T22048 T22059 causeOf Runx3,controls
R16907 T22049 T22052 themeOf perforin,controls
R16908 T22049 T22054 themeOf perforin,expression
R16909 T22050 T22053 themeOf granzyme B,controls
R16910 T22050 T22055 themeOf granzyme B,expression
R16911 T22051 T22056 themeOf IFN-γ,expression
R16912 T22054 T22057 themeOf expression,controls
R16913 T22055 T22058 themeOf expression,controls
R16914 T22056 T22059 themeOf expression,controls
R16915 T22071 T22074 themeOf Eomes,Overexpression
R16916 T22072 T22075 themeOf VP16,Overexpression
R16917 T22076 T22078 themeOf granzyme B,Expression
R16918 T22077 T22079 themeOf IFN-γ,Expression
R16919 T22080 T22081 themeOf granzyme B,staining
R16920 T22086 T22087 themeOf IFN-γ,expression
R16921 T22087 T22088 themeOf expression,essential
R16922 T22089 T22096 themeOf Runx3,present
R16923 T22089 T22097 causeOf Runx3,represses
R16924 T22091 T22097 themeOf Runx1,represses
R16925 T22092 T22098 themeOf Eomes,expression
R16926 T22095 T22099 themeOf IFN-γ,expression
R16927 T22100 T22103 themeOf IFN-γ,expression
R16928 T22101 T22106 causeOf Runx3,activate
R16929 T22102 T22104 themeOf perforin,expression
R16930 T22103 T22105 themeOf expression,participate
R16931 T22104 T22106 themeOf expression,activate
R16932 T22107 T22109 themeOf Gzmb mRNA,expression
R16933 T22107 T22111 causeOf Gzmb mRNA,effect
R16934 T22107 T22112 causeOf Gzmb mRNA,effect
R16935 T22108 T22110 themeOf granzyme B protein,expression
R16936 T22109 T22111 themeOf expression,effect
R16937 T22110 T22112 themeOf expression,effect
R3581 T4567 T4568 themeOf see,increased
R3582 T4532 T4534 themeOf perforin,expression
R3583 T4533 T4535 themeOf granzyme B,expression
R3584 T4537 T4539 themeOf perforin mRNA,expression
R3585 T4570 T4571 themeOf perforin,express
R3586 T4538 T4540 themeOf perforin,expression
R3587 T4541 T4543 themeOf perforin,expression
R3588 T4542 T4544 themeOf Prf1,expression
R3589 T4573 T4576 themeOf granzyme B,expression
R3590 T4543 T4545 themeOf expression,increase
R3591 T4543 T4547 themeOf expression,decrease
R3592 T4543 T4549 themeOf expression,reexpression
R3593 T4544 T4546 themeOf expression,increase
R3594 T4544 T4548 themeOf expression,decrease
R3595 T4544 T4550 themeOf expression,reexpression
R3596 T4574 T4577 themeOf perforin,expression
R3597 T4551 T4554 themeOf granzyme B,undetectable
R3598 T4551 T4556 themeOf granzyme B,up-regulated
R3599 T4551 T4558 themeOf granzyme B,increased
R3600 T4577 T4578 themeOf expression,induced
R3601 T4552 T4555 themeOf Gzmb,undetectable
R3602 T4552 T4557 themeOf Gzmb,up-regulated
R3603 T4552 T4559 themeOf Gzmb,increased
R3604 T4553 T4560 themeOf granzyme B protein,expressed
R3605 T4553 T4561 themeOf granzyme B protein,high
R3606 T4562 T4565 themeOf IFN-γ,expressed
R3607 T4563 T4566 themeOf TNF,expressed
R3608 T4564 T4567 themeOf Fig. 2 A,see
R429 T631 T638 causeOf Runx3,regulates
R430 T631 T639 causeOf Runx3,regulates
R431 T631 T640 causeOf Runx3,regulates
R432 T632 T635 themeOf IFN-γ,expression
R4666 T5866 T5868 themeOf Prf1,regulation
R4667 T5867 T5869 themeOf GzmB,regulation
R4668 T5873 T5874 themeOf TCR,expression
R4669 T5874 T5875 themeOf expression,effect
R4670 T5876 T5877 themeOf Eomes mRNA,induction
R4671 T5878 T5881 themeOf GzmB mRNA,expression
R4672 T5879 T5882 themeOf Eomes mRNA,expressed
R4673 T5880 T5883 themeOf perforin mRNA,reexpression
R4674 T5881 T5884 themeOf expression,preceded
R4675 T5885 T5887 themeOf IFN-γ,production
R4676 T5886 T5888 themeOf perforin,expression
R4677 T5887 T5889 themeOf production,required
R4678 T5888 T5890 themeOf expression,control
R4679 T5890 T5891 themeOf control,contribute
R4680 T5892 T5896 themeOf TCR,induce
R4681 T5893 T5897 themeOf IFN-γ,induces
R4682 T5895 T5898 themeOf perforin,expression
R4683 T5898 T5899 themeOf expression,activates
R527 T633 T636 themeOf perforin,expression
R528 T634 T637 themeOf granzyme B,expression
R529 T635 T638 themeOf expression,regulates
R530 T636 T639 themeOf expression,regulates
R531 T637 T640 themeOf expression,regulates
R5756 T7318 T7320 themeOf Perforin,expression
R5757 T7318 T7322 themeOf Perforin,regulated
R5758 T7319 T7321 themeOf granzyme B,expression
R5759 T7320 T7323 themeOf expression,regulated
R5760 T7321 T7324 themeOf expression,regulated
R5761 T7325 T7331 themeOf IFN-γ,expression
R5762 T7326 T7332 themeOf perforin,expression
R5763 T7327 T7333 themeOf granzyme B,expression
R5764 T7329 T7334 themeOf WT,-deficient
R5765 T7330 T7335 themeOf Tbx21,-deficient
R5766 T7337 T7338 themeOf IFN-γ,produced
R5767 T7340 T7341 themeOf perforin mRNA,expression
R5768 T7341 T7342 themeOf expression,defect
R5769 T7343 T7346 themeOf GzmB mRNA,reduction
R5770 T7344 T7347 themeOf granzyme B protein,expression
R5771 T7345 T7348 themeOf Fig,expression
R5772 T7347 T7349 themeOf expression,decrease
R5773 T7348 T7350 themeOf expression,decrease
R5774 T7355 T7359 causeOf VP16,increased
R5775 T7356 T7358 themeOf perforin,expression
R5776 T7358 T7359 themeOf expression,increased
R5777 T7360 T7364 causeOf Eo-VP16,defect
R5778 T7361 T7363 themeOf IFN-γ,production
R5779 T7363 T7364 themeOf production,defect
R5780 T7365 T7371 causeOf Eo-VP16,induce
R5781 T7366 T7369 themeOf GzmB mRNA,expression
R5782 T7367 T7370 themeOf GzmB mRNA,expression
R5783 T7369 T7371 themeOf expression,induce
R8797 T11240 T11245 themeOf Runx3,expressed
R8802 T11254 T11258 themeOf perforin,expression
R8804 T11255 T11259 themeOf granzyme B,expression
R8805 T11256 T11260 themeOf IFN-γ,expression
R8806 T11257 T11261 themeOf Fig,expression
R8809 T11262 T11264 themeOf perforin mRNA,expression
R8810 T11262 T11265 causeOf perforin mRNA,undetectable
R8812 T11264 T11265 themeOf expression,undetectable
R8817 T11267 T11275 causeOf Runx3,required
R8818 T11267 T11276 causeOf Runx3,required
R8819 T11267 T11277 causeOf Runx3,required
R8820 T11268 T11272 themeOf IFN-γ,production
R8821 T11269 T11273 themeOf TNF,production
R8822 T11270 T11274 themeOf IL-2,production
R8823 T11272 T11275 themeOf production,required
R8824 T11273 T11276 themeOf production,required
R8826 T11274 T11277 themeOf production,required
R8828 T11278 T11281 themeOf Runx3,induces
R8833 T11283 T11290 themeOf perforin,expression
R8834 T11284 T11291 themeOf Eo,overexpression
R8835 T11285 T11292 themeOf VP16,overexpression
R8836 T11286 T11293 themeOf perforin,increase
R8837 T11286 T11294 themeOf perforin,expression
R8843 T11287 T11295 themeOf IFN-γ,expression
R8845 T11288 T11296 themeOf Runx,involving
R8846 T11289 T11297 themeOf T-box transcription factors,involving
R8847 T11291 T11298 causeOf overexpression,led
R8848 T11292 T11299 causeOf overexpression,led
R8849 T11293 T11298 themeOf increase,led
R8850 T11293 T11299 themeOf increase,led
R8851 T11294 T11300 themeOf expression,increase
R8852 T11295 T11301 themeOf expression,increase
R8855 T11302 T11309 causeOf Runx3,regulate
R8856 T11302 T11310 causeOf Runx3,regulate
R8857 T11302 T11311 causeOf Runx3,regulate
R8858 T11303 T11306 themeOf perforin,transcription
R8860 T11304 T11307 themeOf IFN-γ,transcription
R8862 T11305 T11308 themeOf granzyme B,transcription
R8863 T11306 T11309 themeOf transcription,regulate
R8864 T11307 T11310 themeOf transcription,regulate
R8866 T11308 T11311 themeOf transcription,regulate
R8868 T11312 T11319 themeOf Eomes,bound
R8869 T11312 T11320 themeOf Eomes,bound
R8870 T11312 T11321 themeOf Eomes,bound
R8871 T11313 T11322 themeOf Runx3,bound
R8872 T11313 T11323 themeOf Runx3,bound
R8873 T11313 T11324 themeOf Runx3,bound
R8874 T11314 T11319 themeOf Prf1,bound
R8875 T11314 T11322 themeOf Prf1,bound
R8876 T11314 T11318 partOf Prf1,regions
R8877 T11315 T11320 themeOf Ifng,bound
R8878 T11315 T11323 themeOf Ifng,bound
R8879 T11315 T11318 partOf Ifng,regions
R8880 T11316 T11318 partOf Gzmb genes,regions
R8881 T11317 T11321 themeOf Fig,bound
R8882 T11317 T11324 themeOf Fig,bound
R8883 T11317 T11318 partOf Fig,regions
R8884 T11318 T11319 Site regions,bound
R8885 T11318 T11320 Site regions,bound
R8886 T11318 T11321 Site regions,bound
R8887 T11318 T11322 Site regions,bound
R8888 T11318 T11323 Site regions,bound
R8889 T11318 T11324 Site regions,bound
R8891 T11325 T11333 themeOf Runx3,bound
R8894 T11351 T11354 themeOf expression,controlled
R8895 T11331 T11333 themeOf Ifng promoter,bound
R8896 T11334 T11344 themeOf Prf1 TSS,bound
R8897 T11334 T11340 partOf Prf1 TSS,enhancer
R8898 T11335 T11342 themeOf Il2rb gene,target
R8899 T11335 T11341 partOf Il2rb gene,promoter
R8900 T11336 T11343 themeOf Ifng TSS,target
R8901 T11337 T11343 themeOf T-box proteins,target
R8902 T11340 T11344 Site enhancer,bound
R8903 T11341 T11342 Site promoter,target
R8904 T11367 T11371 themeOf perforin,restored
R8905 T11345 T11354 causeOf Runx3,controlled
R8906 T11346 T11351 themeOf CTL effector genes,expression
R8907 T11347 T11352 themeOf Runx3,expressed
R8908 T11348 T11353 themeOf Eo-VP16,expressed
R8909 T11367 T11372 themeOf perforin,expression
R8910 T11368 T11373 themeOf granzyme B,expression
R8911 T11369 T11374 themeOf IFN-γ,expression
R8912 T11370 T11375 themeOf Fig,expression
R8913 T11372 T11376 themeOf expression,restored
R8914 T11373 T11377 themeOf expression,restored
R8915 T11374 T11378 themeOf expression,restored
R8916 T11375 T11379 themeOf expression,restored
R8917 T11381 T11385 themeOf Runx1,up-regulation
R8918 T11382 T11386 causeOf Runx3,suppressed
R8919 T11383 T11387 themeOf Runx1,repression
R8920 T11384 T11387 causeOf Runx3,repression
R8921 T11385 T11386 themeOf up-regulation,suppressed
R8922 T11388 T11396 causeOf Eo-VP16,up-regulate
R8923 T11389 T11393 themeOf perforin,expression
R8924 T11391 T11394 themeOf IFN-γ,expression
R8925 T11392 T11395 themeOf TCR,restimulation
R8926 T11393 T11396 themeOf expression,up-regulate
R8927 T11394 T11397 themeOf expression,induce
R8928 T11395 T11397 causeOf restimulation,induce
R8929 T11397 T11398 themeOf induce,restored
R8930 T11399 T11402 themeOf perforin,expression
R8931 T11403 T11407 themeOf perforin,expression
R8932 T11404 T11408 themeOf granzyme B,expression
R8933 T11407 T11409 themeOf expression,defect
R8934 T11408 T11410 themeOf expression,defect
R8935 T11416 T11421 themeOf perforin/granzyme B,activation
R8936 T11421 T11422 themeOf activation,defective