bionlp-ost-19-BB-rel-train  

BB-rel@ldeleger:BB-rel-16263187 JSONTXT

Annnotations TAB TSV DIC JSON TextAE

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1 0-135 Title denotes Ability of Lactobacillus gasseri K 7 to inhibit Escherichia coli adhesion in vitro on Caco-2 cells and ex vivo on pigs' jejunal tissue.
T3 11-36 Microorganism denotes Lactobacillus gasseri K 7
T4 48-64 Microorganism denotes Escherichia coli
E2 48-64 Lives_In denotes Escherichia coli
E3 48-64 Lives_In denotes Escherichia coli
E1 48-64 Exhibits denotes Escherichia coli
T5 65-73 Phenotype denotes adhesion
T6 86-98 Habitat denotes Caco-2 cells
T8 114-118 Habitat denotes pigs
T7 114-134 Habitat denotes pigs' jejunal tissue
T9 120-127 Habitat denotes jejunal
T2 136-1930 Paragraph denotes The ability of Lactobacillus (Lb.) gasseri K 7 to inhibit adhesion of Escherichia coli O8:K88 to intestinal mucosa was studied on cultured Caco-2 cells and ex vivo on pigs' small intestinal tissue. Lactobacilli were added simultaneously with E. coli, before E. coli and after E. coli for competition, exclusion and displacement assays. The concentration of lactobacilli on fully differentiated Caco-2 cells was 4.5+/-0.3 x 10(8) cfu/well, while the concentration of E. coli varied from 1.5 x 10(6) to 4.3 x 10(8) cfu/well. The number of E. coli adhered to Caco-2 monolayer (cfu/well) was lineary correlated (R(2)=0.97) to the concentration of added cells. In the assay simulating exclusion, E. coli adhesion was reduced by Lb. gasseri K 7 strain by 0.1 to 0.6 log cfu/well. The binding of E. coli was inhibited even more when incubated simultaneously with lactobacilli, particularly at the lowest concentration of E. coli (ratio E. coli/lactobacilli 1:248), where five-times reduction (or 0.7 log) was observed. When adhesion to tissue derived from pigs' jejunum was tested, concentration of E. coli was constant (6.9+/-0.14 x 10(7) cfu/ml), while the concentration of Lb. gasseri K 7 was 5.9 x 10(7) and 1.3 x 10(7) cfu/ml in two independent experiments, respectively. The adhesion of E. coli and Lb. gasseri K 7 cells to jejunal mucosa was similar (1.0+/-0.17 x 10(6) and 1.54+/-0.10 x 10(6) cfu/cm(2)) when the concentrations of single strains in suspensions were approximately the same. No significant competition, exclusion or displacement of E. coli by lactobacilli was observed on jejunal tissue. In conclusion, Lb. gasseri K 7 was found to be effective in reducing E. coli adhesion to Caco-2 enterocytes, but it was not able to do so in ex vivo conditions tested for pig jejunal tissue.
T10 151-182 Microorganism denotes Lactobacillus (Lb.) gasseri K 7
T11 194-202 Phenotype denotes adhesion
T12 206-229 Microorganism denotes Escherichia coli O8:K88
E5 206-229 Lives_In denotes Escherichia coli O8:K88
E6 206-229 Lives_In denotes Escherichia coli O8:K88
E4 206-229 Exhibits denotes Escherichia coli O8:K88
T14 233-243 Habitat denotes intestinal
T13 233-250 Habitat denotes intestinal mucosa
T15 266-287 Habitat denotes cultured Caco-2 cells
T17 303-307 Habitat denotes pigs
T16 303-332 Habitat denotes pigs' small intestinal tissue
T18 309-325 Habitat denotes small intestinal
T19 334-346 Microorganism denotes Lactobacilli
T20 378-385 Microorganism denotes E. coli
T21 394-401 Microorganism denotes E. coli
T22 412-419 Microorganism denotes E. coli
T23 493-505 Microorganism denotes lactobacilli
E7 493-505 Lives_In denotes lactobacilli
T24 509-542 Habitat denotes fully differentiated Caco-2 cells
T25 602-609 Microorganism denotes E. coli
E8 602-609 Lives_In denotes E. coli
T26 673-680 Microorganism denotes E. coli
E9 673-680 Lives_In denotes E. coli
T27 692-698 Habitat denotes Caco-2
T28 827-834 Microorganism denotes E. coli
E10 827-834 Exhibits denotes E. coli
T29 835-843 Phenotype denotes adhesion
T30 859-874 Microorganism denotes Lb. gasseri K 7
T31 914-921 Phenotype denotes binding
T32 925-932 Microorganism denotes E. coli
E11 925-932 Exhibits denotes E. coli
T33 992-1004 Microorganism denotes lactobacilli
T34 1050-1057 Microorganism denotes E. coli
T35 1065-1072 Microorganism denotes E. coli
T36 1073-1085 Microorganism denotes lactobacilli
T37 1153-1161 Phenotype denotes adhesion
T38 1165-1198 Habitat denotes tissue derived from pigs' jejunum
T40 1185-1189 Habitat denotes pigs
T39 1185-1198 Habitat denotes pigs' jejunum
T41 1228-1235 Microorganism denotes E. coli
E12 1228-1235 Lives_In denotes E. coli
T42 1305-1320 Microorganism denotes Lb. gasseri K 7
E13 1305-1320 Lives_In denotes Lb. gasseri K 7
T43 1410-1418 Phenotype denotes adhesion
T44 1422-1429 Microorganism denotes E. coli
E15 1422-1429 Lives_In denotes E. coli
E14 1422-1429 Exhibits denotes E. coli
T45 1434-1449 Microorganism denotes Lb. gasseri K 7
E17 1434-1449 Lives_In denotes Lb. gasseri K 7
E18 1434-1449 Lives_In denotes Lb. gasseri K 7
E16 1434-1449 Exhibits denotes Lb. gasseri K 7
T46 1459-1466 Habitat denotes jejunal
T47 1459-1473 Habitat denotes jejunal mucosa
T48 1684-1691 Microorganism denotes E. coli
E19 1684-1691 Lives_In denotes E. coli
T49 1695-1707 Microorganism denotes lactobacilli
E20 1695-1707 Lives_In denotes lactobacilli
T50 1724-1731 Habitat denotes jejunal
T51 1724-1738 Habitat denotes jejunal tissue
T52 1755-1770 Microorganism denotes Lb. gasseri K 7
E21 1755-1770 Lives_In denotes Lb. gasseri K 7
T53 1809-1816 Microorganism denotes E. coli
E23 1809-1816 Lives_In denotes E. coli
E24 1809-1816 Lives_In denotes E. coli
E22 1809-1816 Exhibits denotes E. coli
T54 1817-1825 Phenotype denotes adhesion
T55 1829-1847 Habitat denotes Caco-2 enterocytes
T57 1911-1914 Habitat denotes pig
T56 1911-1929 Habitat denotes pig jejunal tissue
T58 1915-1922 Habitat denotes jejunal
R1 E2 T4 Microorganism Escherichia coli,Escherichia coli
R10 E6 T13 Location Escherichia coli O8:K88,intestinal mucosa
R11 E4 T12 Microorganism Escherichia coli O8:K88,Escherichia coli O8:K88
R12 E4 T11 Property Escherichia coli O8:K88,adhesion
R13 E7 T23 Microorganism lactobacilli,lactobacilli
R14 E7 T24 Location lactobacilli,fully differentiated Caco-2 cells
R15 E8 T25 Microorganism E. coli,E. coli
R16 E8 T24 Location E. coli,fully differentiated Caco-2 cells
R17 E9 T26 Microorganism E. coli,E. coli
R18 E9 T27 Location E. coli,Caco-2
R19 E10 T28 Microorganism E. coli,E. coli
R2 E2 T7 Location Escherichia coli,pigs' jejunal tissue
R20 E10 T29 Property E. coli,adhesion
R21 E11 T32 Microorganism E. coli,E. coli
R22 E11 T31 Property E. coli,binding
R23 E12 T41 Microorganism E. coli,E. coli
R24 E12 T38 Location E. coli,tissue derived from pigs' jejunum
R25 E13 T42 Microorganism Lb. gasseri K 7,Lb. gasseri K 7
R26 E13 T38 Location Lb. gasseri K 7,tissue derived from pigs' jejunum
R27 E15 T44 Microorganism E. coli,E. coli
R28 E15 T47 Location E. coli,jejunal mucosa
R29 E14 T44 Microorganism E. coli,E. coli
R3 E3 T4 Microorganism Escherichia coli,Escherichia coli
R30 E14 T43 Property E. coli,adhesion
R31 E17 T45 Microorganism Lb. gasseri K 7,Lb. gasseri K 7
R32 E17 T47 Location Lb. gasseri K 7,jejunal mucosa
R33 E18 T45 Microorganism Lb. gasseri K 7,Lb. gasseri K 7
R34 E18 T46 Location Lb. gasseri K 7,jejunal
R35 E16 T45 Microorganism Lb. gasseri K 7,Lb. gasseri K 7
R36 E16 T43 Property Lb. gasseri K 7,adhesion
R37 E19 T48 Microorganism E. coli,E. coli
R38 E19 T51 Location E. coli,jejunal tissue
R39 E20 T49 Microorganism lactobacilli,lactobacilli
R4 E3 T6 Location Escherichia coli,Caco-2 cells
R40 E20 T51 Location lactobacilli,jejunal tissue
R41 E21 T52 Microorganism Lb. gasseri K 7,Lb. gasseri K 7
R42 E21 T55 Location Lb. gasseri K 7,Caco-2 enterocytes
R43 E23 T53 Microorganism E. coli,E. coli
R44 E23 T55 Location E. coli,Caco-2 enterocytes
R45 E24 T53 Microorganism E. coli,E. coli
R46 E24 T56 Location E. coli,pig jejunal tissue
R47 E22 T53 Microorganism E. coli,E. coli
R48 E22 T54 Property E. coli,adhesion
R5 E1 T4 Microorganism Escherichia coli,Escherichia coli
R6 E1 T5 Property Escherichia coli,adhesion
R7 E5 T12 Microorganism Escherichia coli O8:K88,Escherichia coli O8:K88
R8 E5 T14 Location Escherichia coli O8:K88,intestinal
R9 E6 T12 Microorganism Escherichia coli O8:K88,Escherichia coli O8:K88