BB-rel@ldeleger:BB-rel-47483 JSONTXT

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Id Subject Object Predicate Lexical cue
T3 0-20 Phenotype denotes Ampicillin-resistant
T1 0-134 Title denotes Ampicillin-resistant Haemophilus influenzae type B possessing a TEM-type beta-lactamase but little permeability barrier to ampicillin.
T4 21-50 Microorganism denotes Haemophilus influenzae type B
E1 21-50 Exhibits denotes Haemophilus influenzae type B
T5 135-155 Phenotype denotes Ampicillin-resistant
T2 135-1070 Paragraph denotes Ampicillin-resistant Haemophilus influenzae type B have been reported only during the past year. Five clinical isolates from the U.S. and Germany all had the TEM-type beta-lactamase which is known to be transferred widely among other gram-negative bacilli. Unlike those bacilli, however, the H. influenzae cell had very little barrier to entry of penicillins. This greater permeability of the H. influenzae cell to penicillins appeared to reduce the protective effect of its beta-lactamase, in that acquisition of the TEM-type beta-lactamase increased levels of resistance to penicillins much less for individual cells of H. influenzae than for those of Escherichia coli. Large inocula of either species appeared highly resistant. The unusually low level of resistance of individual cells of H. influenzae containing the TEM-type beta-lactamase may have delayed their emergence or recognition, and has unresolved clinical implications.
T6 156-185 Microorganism denotes Haemophilus influenzae type B
E2 156-185 Lives_In denotes Haemophilus influenzae type B
E3 156-185 Lives_In denotes Haemophilus influenzae type B
E4 156-185 Lives_In denotes Haemophilus influenzae type B
E5 156-185 Exhibits denotes Haemophilus influenzae type B
E6 156-185 Exhibits denotes Haemophilus influenzae type B
T7 237-245 Habitat denotes clinical
T8 264-268 Geographical denotes U.S.
T9 273-280 Geographical denotes Germany
T10 369-382 Phenotype denotes gram-negative
T11 383-390 Microorganism denotes bacilli
E7 383-390 Exhibits denotes bacilli
T12 405-412 Microorganism denotes bacilli
T13 427-440 Microorganism denotes H. influenzae
T14 528-541 Microorganism denotes H. influenzae
T15 697-722 Phenotype denotes resistance to penicillins
T16 757-770 Microorganism denotes H. influenzae
E8 757-770 Exhibits denotes H. influenzae
E9 757-770 Exhibits denotes H. influenzae
T17 789-805 Microorganism denotes Escherichia coli
E10 789-805 Exhibits denotes Escherichia coli
E11 789-805 Exhibits denotes Escherichia coli
T18 855-864 Phenotype denotes resistant
T19 893-903 Phenotype denotes resistance
T20 927-940 Microorganism denotes H. influenzae
E12 927-940 Exhibits denotes H. influenzae
R1 E1 T4 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R10 E5 T5 Property Haemophilus influenzae type B,Ampicillin-resistant
R11 E6 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R12 E6 T10 Property Haemophilus influenzae type B,gram-negative
R13 E7 T11 Microorganism bacilli,bacilli
R14 E7 T10 Property bacilli,gram-negative
R15 E8 T16 Microorganism H. influenzae,H. influenzae
R16 E8 T18 Property H. influenzae,resistant
R17 E9 T16 Microorganism H. influenzae,H. influenzae
R18 E9 T15 Property H. influenzae,resistance to penicillins
R19 E10 T17 Microorganism Escherichia coli,Escherichia coli
R2 E1 T3 Property Haemophilus influenzae type B,Ampicillin-resistant
R20 E10 T15 Property Escherichia coli,resistance to penicillins
R21 E11 T17 Microorganism Escherichia coli,Escherichia coli
R22 E11 T18 Property Escherichia coli,resistant
R23 E12 T20 Microorganism H. influenzae,H. influenzae
R24 E12 T19 Property H. influenzae,resistance
R3 E2 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R4 E2 T9 Location Haemophilus influenzae type B,Germany
R5 E3 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R6 E3 T8 Location Haemophilus influenzae type B,U.S.
R7 E4 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R8 E4 T7 Location Haemophilus influenzae type B,clinical
R9 E5 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B