BB-norm+ner@ldeleger:BB-norm+ner-47483 JSONTXT

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Id Subject Object Predicate Lexical cue NCBI_Taxonomy OntoBiotope
T3 0-20 Phenotype denotes Ampicillin-resistant OBT:002762
T1 0-134 Title denotes Ampicillin-resistant Haemophilus influenzae type B possessing a TEM-type beta-lactamase but little permeability barrier to ampicillin.
T4 21-50 Microorganism denotes Haemophilus influenzae type B 727
T5 135-155 Phenotype denotes Ampicillin-resistant OBT:002762
T2 135-1070 Paragraph denotes Ampicillin-resistant Haemophilus influenzae type B have been reported only during the past year. Five clinical isolates from the U.S. and Germany all had the TEM-type beta-lactamase which is known to be transferred widely among other gram-negative bacilli. Unlike those bacilli, however, the H. influenzae cell had very little barrier to entry of penicillins. This greater permeability of the H. influenzae cell to penicillins appeared to reduce the protective effect of its beta-lactamase, in that acquisition of the TEM-type beta-lactamase increased levels of resistance to penicillins much less for individual cells of H. influenzae than for those of Escherichia coli. Large inocula of either species appeared highly resistant. The unusually low level of resistance of individual cells of H. influenzae containing the TEM-type beta-lactamase may have delayed their emergence or recognition, and has unresolved clinical implications.
T6 156-185 Microorganism denotes Haemophilus influenzae type B 727
T7 237-245 Habitat denotes clinical OBT:003220
T8 369-382 Phenotype denotes gram-negative OBT:000648
T9 383-390 Microorganism denotes bacilli 91061
T10 405-412 Microorganism denotes bacilli 91061
T11 427-440 Microorganism denotes H. influenzae 727
T12 528-541 Microorganism denotes H. influenzae 727
T13 697-722 Phenotype denotes resistance to penicillins OBT:002829
T14 757-770 Microorganism denotes H. influenzae 727
T15 789-805 Microorganism denotes Escherichia coli 562
T16 855-864 Phenotype denotes resistant OBT:002829
T17 893-903 Phenotype denotes resistance OBT:002829
T18 927-940 Microorganism denotes H. influenzae 727