BB-kb+ner@ldeleger:BB-kb+ner-47483 JSONTXT

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Id Subject Object Predicate Lexical cue NCBI_Taxonomy OntoBiotope
T3 0-20 Phenotype denotes Ampicillin-resistant OBT:002762
T1 0-134 Title denotes Ampicillin-resistant Haemophilus influenzae type B possessing a TEM-type beta-lactamase but little permeability barrier to ampicillin.
T4 21-50 Microorganism denotes Haemophilus influenzae type B 727
E1 21-50 Exhibits denotes Haemophilus influenzae type B
T5 135-155 Phenotype denotes Ampicillin-resistant OBT:002762
T2 135-1070 Paragraph denotes Ampicillin-resistant Haemophilus influenzae type B have been reported only during the past year. Five clinical isolates from the U.S. and Germany all had the TEM-type beta-lactamase which is known to be transferred widely among other gram-negative bacilli. Unlike those bacilli, however, the H. influenzae cell had very little barrier to entry of penicillins. This greater permeability of the H. influenzae cell to penicillins appeared to reduce the protective effect of its beta-lactamase, in that acquisition of the TEM-type beta-lactamase increased levels of resistance to penicillins much less for individual cells of H. influenzae than for those of Escherichia coli. Large inocula of either species appeared highly resistant. The unusually low level of resistance of individual cells of H. influenzae containing the TEM-type beta-lactamase may have delayed their emergence or recognition, and has unresolved clinical implications.
T6 156-185 Microorganism denotes Haemophilus influenzae type B 727
E4 156-185 Lives_In denotes Haemophilus influenzae type B
E5 156-185 Exhibits denotes Haemophilus influenzae type B
E6 156-185 Exhibits denotes Haemophilus influenzae type B
T7 237-245 Habitat denotes clinical OBT:003220
T8 369-382 Phenotype denotes gram-negative OBT:000648
T9 383-390 Microorganism denotes bacilli 91061
E7 383-390 Exhibits denotes bacilli
T10 405-412 Microorganism denotes bacilli 91061
T11 427-440 Microorganism denotes H. influenzae 727
T12 528-541 Microorganism denotes H. influenzae 727
T13 697-722 Phenotype denotes resistance to penicillins OBT:002829
T14 757-770 Microorganism denotes H. influenzae 727
E8 757-770 Exhibits denotes H. influenzae
E9 757-770 Exhibits denotes H. influenzae
T15 789-805 Microorganism denotes Escherichia coli 562
E10 789-805 Exhibits denotes Escherichia coli
E11 789-805 Exhibits denotes Escherichia coli
T16 855-864 Phenotype denotes resistant OBT:002829
T17 893-903 Phenotype denotes resistance OBT:002829
T18 927-940 Microorganism denotes H. influenzae 727
E12 927-940 Exhibits denotes H. influenzae
R1 E1 T4 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R10 E7 T8 Property bacilli,gram-negative
R11 E8 T14 Microorganism H. influenzae,H. influenzae
R12 E8 T16 Property H. influenzae,resistant
R13 E9 T14 Microorganism H. influenzae,H. influenzae
R14 E9 T13 Property H. influenzae,resistance to penicillins
R15 E10 T15 Microorganism Escherichia coli,Escherichia coli
R16 E10 T13 Property Escherichia coli,resistance to penicillins
R17 E11 T15 Microorganism Escherichia coli,Escherichia coli
R18 E11 T16 Property Escherichia coli,resistant
R19 E12 T18 Microorganism H. influenzae,H. influenzae
R2 E1 T3 Property Haemophilus influenzae type B,Ampicillin-resistant
R20 E12 T17 Property H. influenzae,resistance
R3 E4 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R4 E4 T7 Location Haemophilus influenzae type B,clinical
R5 E5 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R6 E5 T5 Property Haemophilus influenzae type B,Ampicillin-resistant
R7 E6 T6 Microorganism Haemophilus influenzae type B,Haemophilus influenzae type B
R8 E6 T8 Property Haemophilus influenzae type B,gram-negative
R9 E7 T9 Microorganism bacilli,bacilli