UseCases_ArguminSci_Discourse  

PubMed:22171043 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-88 DRI_Outcome denotes Optimizing the decoding of movement goals from local field potentials in macaque cortex.
T2 89-228 DRI_Outcome denotes The successful development of motor neuroprosthetic devices hinges on the ability to accurately and reliably decode signals from the brain.
T3 229-381 DRI_Challenge denotes Motor neuroprostheses are widely investigated in behaving non-human primates, but technical constraints have limited progress in optimizing performance.
T4 382-539 DRI_Background denotes In particular, the organization of movement-related neuronal activity across cortical layers remains poorly understood due, in part, to the widespread use of
T5 540-569 Token_Label.OUTSIDE denotes fixed-geometry multielectrode
T6 570-577 DRI_Background denotes arrays.
T7 578-753 DRI_Approach denotes In this study, we use chronically implanted multielectrode arrays with individually movable electrodes to examine how the encoding of movement goals depends on cortical depth.
T8 754-946 DRI_Approach denotes In a series of recordings spanning several months, we varied the depth of each electrode in the prearcuate gyrus of frontal cortex in two monkeys as they performed memory-guided eye movements.
T9 947-1113 DRI_Outcome denotes We decode eye movement goals from local field potentials (LFPs) and multiunit spiking activity recorded across a range of depths up to 3 mm from the cortical surface.
T10 1114-1325 DRI_Outcome denotes We show that both LFP and multiunit signals yield the highest decoding performance at superficial sites, within 0.5 mm of the cortical surface, while performance degrades substantially at sites deeper than 1 mm.
T11 1326-1473 DRI_Outcome denotes We also analyze performance by varying bandpass filtering characteristics and simulating changes in microelectrode array channel count and density.
T12 1474-1518 DRI_Outcome denotes The results indicate that the performance of
T13 1519-1544 Token_Label.OUTSIDE denotes LFP-based neuroprostheses
T14 1545-1666 DRI_Outcome denotes strongly depends on recording configuration and that recording depth is a critical parameter limiting system performance.