UseCases_ArguminSci_Discourse  

PubMed:17134566 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-95 DRI_Background denotes [Clinicopathologic study of breast cancer with features of endocrine ductal carcinoma-in-situ].
T2 101-233 DRI_Background denotes TIVE: To study the clinicopathologic features and differential diagnosis of 18 cases of endocrine ductal carcinoma-in-situ (E-DCIS).
T3 243-373 DRI_Background denotes Eighteen cases of breast cancer with features of E-DCIS were studied by light microscopy, histochemistry and immunohistochemistry.
T4 374-631 DRI_Approach denotes E-DCIS was diagnosed if the histologic patterns were compatible with those described in the literature and at least 50% of the tumor cells expressing two of the three neuroendocrine markers employed (chromogranin, synaptophysin and neuron-specific enolase).
T5 641-679 DRI_Background denotes E-DCIS tended to occur in older women.
T6 680-740 DRI_Approach denotes All the patients were over 61 years old (mean age=71 years).
T7 741-822 DRI_Background denotes The presenting symptoms were either palpable breast mass or had nipple discharge.
T8 823-899 DRI_Unspecified denotes Histologically, E-DCIS demonstrated an expansile intraductal growth pattern.
T9 900-975 DRI_Background denotes Intraductal papilloma was not uncommon at the peripheral area of the tumor.
T10 976-1135 DRI_Background denotes The tumor cells were polygonal, oval or spindle in shape and contained abundant eosinophilic to granular cytoplasm and mildly to moderately pleomorphic nuclei.
T11 1136-1261 DRI_Background denotes Intracellular or extracellular mucin was highlighted by periodic acid-Schiff (with diastase digestion) or alcian blue stains.
T12 1262-1315 DRI_Background denotes Some tumor cells assumed a signet-ring configuration.
T13 1316-1405 DRI_Approach denotes All the three neuroendocrine markers were expressed by more than 50% of the E-DCIS cells.
T14 1406-1488 DRI_Background denotes The neuroendocrine differentiation was further confirmed in some cases by CD57 and
T15 1489-1508 Token_Label.OUTSIDE denotes CD56 immunostaining
T16 1508-1509 DRI_Background denotes .
T17 1510-1660 DRI_Approach denotes Pagetoid spread into adjacent ductolobular units was frequently seen in E-DCIS, and the expanded lobules were often not rimmed by myoepithelial cells.
T18 1661-1739 DRI_Background denotes These two features helped to distinguish E-DCIS from usual ductal hyperplasia.
T19 1753-1871 DRI_Background denotes E-DCIS represents a subgroup of low-grade DCIS, which carries characteristic morphologic features and immunophenotype.
T20 1872-1938 DRI_Background denotes Conventional light microscopy usually permits a correct diagnosis.
T21 1939-2028 DRI_Background denotes Ancillary histochemical and immunohistochemical studies can be helpful in doubtful cases.