UseCases_ArguminSci_Discourse  

Documents (562) JSON TSV

source DB source ID text size updated at # proj. # Ann. updated_at
PubMed 21454543 Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). Mutations in leucine-rich repeat kinase 2 (LRRK2) are currently the most common genetic cause of familial 1.88 KB 2020-01-21 33 19
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PubMed 24550389 Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex. DNA mismatch repair is initiated by either the Msh2-Msh6 or the Ms 1.61 KB 2020-01-28 29 14
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PubMed 24403070 Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease. Crossing over between homologous chromosomes is initiated in meiotic prophase in most sexually re 1.17 KB 2020-01-28 28 7
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PubMed 12738769 Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta? Amyloid-beta (Abe 1.92 KB 2015-11-22 28 11
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PubMed 8910404 Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair. DNA mismatch repair plays a key role in the maintenance of genetic fidelity. Mutations in the human mismatc 1.13 KB 2020-01-28 28 8
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PubMed 16150730 RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. beta-Amyloid peptides (Abeta) that form the senile plaques of Alzhe 1.48 KB 2015-11-22 28 10
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PubMed 24443562 The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions. MutLγ, a heterodimer of the MutL homologues Mlh1 and Mlh3, plays a critical role 1.57 KB 2020-02-21 28 12
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PubMed 12665519 Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity. The amyloid beta peptides (Abeta) are the major components of the senile plaque 1.99 KB 2015-11-22 28 17
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PubMed 17855343 Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. Numerous studies have now shown that the amyloid beta-protein (Abeta), the principal component of c 1.44 KB 2015-12-25 28 8
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PubMed 15772078 Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor p 1.83 KB 2015-11-22 27 10
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