Systems_Biology  

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PMC 4946111 Where next for the reproducibility agenda in computational biology? Abstract Background The concept of reproducibility is a foundation of the scientific method. With the arrival of fast and powerful 38.1 KB 2020-09-16 3
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PMC 4895898 Evaluation of rate law approximations in bottom-up kinetic models of metabolism Abstract Background The mechanistic description of enzyme kinetics in a dynamic model of metabolism requires specifyin 55.9 KB 2020-09-16 3
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PMC 4888568 A rule-based model of insulin signalling pathway Abstract Background The insulin signalling pathway (ISP) is an important biochemical pathway, which regulates some fundamental biological functions s 43.2 KB 2020-09-15 3
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PMC 4895706 A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae Abstract Background Expression quantitative trait locus (eQTL) analysis has been widely used to understand 32 KB 2020-09-16 3
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PMC 4674863 A model for gene deregulation detection using expression data Abstract In tumoral cells, gene regulation mechanisms are severely altered. Genes that do not react normally to their regulators' activi 26.2 KB 2020-09-15 3
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PMC 4654848 Reconstruction of gene networks using prior knowledge Abstract Background Reconstructing gene regulatory networks (GRNs) from expression data is a challenging task that has become essential to the u 44.5 KB 2020-09-15 3
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PMC 4617482 Conditional robustness analysis for fragility discovery and target identification in biochemical networks and in cancer systems biology Abstract Background The study of cancer therapy is a key issue 85.5 KB 2020-09-15 3
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PMC 4574162 Exploring causal networks underlying fat deposition and muscularity in pigs through the integration of phenotypic, genotypic and transcriptomic data Abstract Background Joint modeling and analysis o 30.9 KB 2020-09-15 3
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PMC 4531511 Stochastic simulation of Boolean rxncon models: towards quantitative analysis of large signaling networks Abstract Background Cellular decision-making is governed by molecular networks that are high 34.2 KB 2020-09-15 3
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PMC 4407080 KPP: KEGG Pathway Painter Abstract Background High-throughput technologies became common tools to decipher genome-wide changes of gene expression (GE) patterns. Functional analysis of GE patterns is 11.7 KB 2020-09-16 3
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