RELISH-DB

Documents (163,268) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	17928366	MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments. In this study, we provide novel insight into the mechanism of how ERK2 can be sorted to different int	1.4 KB	2020-04-24	1	-
PubMed	19244124	Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy. The mitogen-activated protein kinase (MAPK) signal transduction	1.58 KB	2020-04-24	1	-
PubMed	19805545	Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. Kinase activity is known as the key biochemical property of MAPKs. Here, we report that ERK1/2 also utilizes i	1.88 KB	2020-04-24	22	-
PubMed	20079430	MAP kinases have different functions in Dictyostelium G protein-mediated signaling. Extracellular signal regulated kinases (ERKs) are a class of MAP kinases that function in many signaling pathways in	1.34 KB	2016-07-04	2	-
PubMed	20811985	Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases. Accumulating evidence indicates that p44(ERK1) and p42(ERK2) mitogen-activated protein kinases (MAPKs) have distinct	1.14 KB	2016-07-08	2	-
PubMed	24089523	Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration. Histone deacetylase 6 (HDAC6) is well known for its ability to prom	1.48 KB	2017-02-08	24	-
PubMed	26235619	Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development. ERK1 and ERK2 are the effector kinases of the ERK1/2 MAP-kinase signaling pathway, which plays a central role in transducing sign	1.02 KB	2016-01-25	2	-
PubMed	27376062	ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy? The MAP kinase signaling cascade Ras/Raf/MEK/ERK has been involved in a large variety of cellular and physiological processes that a	1.54 KB	2017-09-04	3	-
PubMed	29454854	ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway. The RAS-regulated RAF-MEK1/2-ERK1/2 signalling pathway is de-regulated in a variety of cancers due to mutations i	1.81 KB	2020-04-24	1	-
PubMed	19114553	Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins. Subcellular localization influences the natu	1.53 KB	2020-04-24	2	-