PubMed:24035784 / 1454-1870 10 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
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T3 | 0-416 | RESULTS | denotes | HPB-ALL cells treated with PUGNAc displayed a significant reduction in DNA fragmentation after TBT-induced apoptosis. DFF45, the protein that inhibits the endonuclease DFF40, was identified to be O-GlcNAc modified. O-GlcNAcylated DFF45 appeared to be more resistant to caspase cleavage during apoptosis. Our results suggest that a decrease in the O-GlcNAc modification on DFF45 occurs before its cleavage by caspase. |