PubMed_ArguminSci  

PubMed:31672727 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 105-251 DRI_Challenge denotes re important nutrients for animals because they are necessary for protein synthesis in particular during growth, as well as for neurotransmission.
T2 252-362 DRI_Background denotes However, little is known about how animals use past experience to guide their search for amino-acid-rich food.
T3 363-557 DRI_Outcome denotes We reasoned that the larvae of Drosophila melanogaster are suitable for investigating this topic because they are the feeding and growth stages in the life cycle of these holometabolous insects.
T4 558-736 DRI_Approach denotes Specifically, we investigated whether experiencing an odour with a 20 amino-acid mixture as a semi-natural tastant during training establishes odour-tastant associative memories.
T5 737-902 DRI_Background denotes Across a broad concentration range (0.01-20 mmol l-1), such an amino-acid mixture was found to have a rewarding effect, establishing appetitive memory for the odour.
T6 903-1114 DRI_Outcome denotes To our surprise, however, manipulation of the test conditions revealed that relatively high concentrations of the amino-acid mixture (3.3 mmol l-1 and higher) in addition establish aversive memory for the odour.
T7 1115-1360 DRI_Approach denotes We then characterized both of these oppositely valenced memories in terms of their dependency on the number of training trials, their temporal stability, their modulation through starvation and the specific changes in locomotion underlying them.
T8 1361-1554 DRI_Background denotes Collectively, and in the light of what is known about the neuronal organization of odour-food memory in larval D. melanogaster, our data suggest that these memories are established in parallel.
T9 1555-1770 DRI_Outcome denotes We discuss the similarity of our results to what has been reported for sodium chloride, and the possible neurogenetic bases for concentration-dependent changes in valence when these tastants are used as reinforcers.