Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
97-244 |
DRI_Background |
denotes |
The use of a yeast cell wall extract derived from Saccharomyces cerevisiae (Actigen(®)) has been proposed as an alternative to in-feed antibiotics. |
T2 |
245-420 |
DRI_Background |
denotes |
This experiment was conducted to investigate the efficacy of yeast cell extract as an alternative to zinc bacitracin or salinomycin using a necrotic enteritis challenge model. |
T3 |
421-516 |
DRI_Background |
denotes |
A feeding study was conducted using 480-day-old male Ross 308 chicks assigned to 48 floor pens. |
T4 |
575-794 |
DRI_Background |
denotes |
The factors were: challenge (- or +) and feed additive (control, zinc bacitracin at 100/50 mg/kg, yeast cell wall extract at 400/800/200 mg/kg, or salinomycin at 60 mg/kg in starter, grower, and finisher, respectively). |
T5 |
795-942 |
DRI_Background |
denotes |
Diets based on wheat, sorghum, soybean meal, meat and bone meal, and canola meal were formulated according to the Ross 308 nutrient specifications. |
T6 |
943-1129 |
DRI_Approach |
denotes |
Birds were challenged using a previously established protocol (attenuated Eimeria spp oocysts) on d 9 and 10(8) to 10(9) Clostridium perfringens (type A strain EHE-NE18) on d 14 and 15). |
T7 |
1130-1210 |
DRI_Background |
denotes |
Challenged and unchallenged birds were partitioned to avoid cross contamination. |
T8 |
1211-1337 |
DRI_Background |
denotes |
Challenged birds had lower weight gain, feed intake and livability compared to unchallenged birds on d 24 and d 35 (P < 0.05). |
T9 |
1338-1497 |
DRI_Background |
denotes |
Birds given zinc bacitracin, yeast cell wall extract, or salinomycin had improved weight gain and livability when compared to control birds given no additives. |
T10 |
1498-1606 |
DRI_Background |
denotes |
Challenge × additive interactions were observed for feed intake and weight gain on d 24 and d 35 (P < 0.01). |
T11 |
1607-1737 |
DRI_Outcome |
denotes |
The additives all had a greater positive impact on feed intake, weight gain, and livability in challenged than unchallenged birds. |
T12 |
1738-1885 |
DRI_Outcome |
denotes |
All challenged birds showed higher necrotic enteritis lesion scores in the small intestine sections when compared to unchallenged birds (P < 0.01). |
T13 |
1886-2027 |
DRI_Background |
denotes |
Birds fed yeast cell wall extract exhibited increased villus height, decreased crypt depth, and increased villus:crypt ratio when challenged. |
T14 |
2028-2180 |
DRI_Background |
denotes |
Yeast cell wall extract, zinc bacitracin, and salinomycin were effective in preventing performance decline from necrotic enteritis in the current study. |
T15 |
2181-2288 |
DRI_Background |
denotes |
This study indicates that yeast cell wall extract has promise as a tool for controlling necrotic enteritis. |