PubMed_ArguminSci  

PubMed:22764238 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 83-317 DRI_Background denotes Neural activity within HVC (proper name), a premotor nucleus of the songbird telencephalon analogous to premotor cortical regions in mammals, controls the temporal structure of learned song in male zebra finches (Taeniopygia guttata).
T2 318-447 DRI_Approach denotes HVC is composed of a superficially isomorphic neuronal mosaic, implying that song is encoded in a distributed network within HVC.
T3 448-508 DRI_Approach denotes Here, we combined HVC microlesions (10% focal ablation) with
T4 540-618 DRI_Approach denotes gene (IEG) labeling to explore the network architecture of HVC during singing.
T5 619-743 DRI_Outcome denotes Microlesions produce a transient disruption of HVC activity that results in a temporary (≈ 1 week) loss of vocal patterning.
T6 958-1009 DRI_Background denotes Labeling returned once birds recovered their songs.
T7 1010-1262 DRI_Approach denotes Axial swaths of unlabeled cells occurred whether microlesions were located at rostral or caudal poles of HVC, indicating that the localized reduction in IEG labeling could not be attributable solely to transection of afferents that enter HVC rostrally.
T8 1263-1424 DRI_Approach denotes The asymmetrical pattern of reduced IEG labeling could be explained if synaptic connectivity within HVC is organized preferentially within the rostrocaudal axis.
T9 1425-1606 DRI_Background denotes In vivo retrograde tracer injections and in vitro stimulation and recording experiments in horizontal slices of HVC confirmed a rostrocaudal organization of HVC neural connectivity.
T10 1607-1735 DRI_Outcome denotes Our findings suggest that HVC contains an axially organized network architecture that may encode the temporal structure of song.