PubMed:15190355 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 94-191 DRI_Background denotes Shaping a developing organ or embryo relies on the spatial regulation of cell division and shape.
T2 192-305 DRI_Background denotes However, morphogenesis also occurs through changes in cell-neighbourhood relationships produced by intercalation.
T3 306-435 DRI_Background denotes Intercalation poses a special problem in epithelia because of the adherens junctions, which maintain the integrity of the tissue.
T4 436-642 DRI_Approach denotes Here we address the mechanism by which an ordered process of cell intercalation directs polarized epithelial morphogenesis during germ-band elongation, the developmental elongation of the Drosophila embryo.
T5 643-802 DRI_Approach denotes Intercalation progresses because junctions are spatially reorganized in the plane of the epithelium following an ordered pattern of disassembly and reassembly.
T6 803-944 DRI_Background denotes The planar remodelling of junctions is not driven by external forces at the tissue boundaries but depends on local forces at cell boundaries.
T7 945-1127 DRI_Background denotes Myosin II is specifically enriched in disassembling junctions, and its planar polarized localization and activity are required for planar junction remodelling and cell intercalation.
T8 1128-1233 DRI_Background denotes This simple cellular mechanism provides a general model for polarized morphogenesis in epithelial organs.