| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-137 |
Sentence |
denotes |
Cloning of tangerine from tomato reveals a carotenoid isomerase essential for the production of beta-carotene and xanthophylls in plants. |
| T2 |
138-263 |
Sentence |
denotes |
Carotenoid biosynthesis in plants has been described at the molecular level for most of the biochemical steps in the pathway. |
| T3 |
264-410 |
Sentence |
denotes |
However, the cis-trans isomerization of carotenoids, which is known to occur in vivo, has remained a mystery since its discovery five decades ago. |
| T4 |
411-561 |
Sentence |
denotes |
To elucidate the molecular mechanism of carotenoid isomerization, we have taken a genetic map-based approach to clone the tangerine locus from tomato. |
| T5 |
562-736 |
Sentence |
denotes |
Fruit of tangerine are orange and accumulate prolycopene (7Z,9Z,7'Z,9'Z-tetra-cis-lycopene) instead of the all-trans-lycopene, which normally is synthesized in the wild type. |
| T6 |
737-889 |
Sentence |
denotes |
Our data indicate that the tangerine gene, designated CRTISO, encodes an authentic carotenoid isomerase that is required during carotenoid desaturation. |
| T7 |
890-988 |
Sentence |
denotes |
CRTISO is a redox-type enzyme structurally related to the bacterial-type phytoene desaturase CRTI. |
| T8 |
989-1037 |
Sentence |
denotes |
Two alleles of tangerine have been investigated. |
| T9 |
1038-1184 |
Sentence |
denotes |
In tangerine(mic), loss of function is attributable to a deletion mutation in CRTISO, and in tangerine(3183), expression of this gene is impaired. |
| T10 |
1185-1294 |
Sentence |
denotes |
CRTISO from tomato is expressed in all green tissues but is upregulated during fruit ripening and in flowers. |
| T11 |
1295-1442 |
Sentence |
denotes |
The function of carotene isomerase in plants presumably is to enable carotenoid biosynthesis to occur in the dark and in nonphotosynthetic tissues. |
