PubMed:33161199 JSONTXT 19 Projects

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Id Subject Object Predicate Lexical cue
T1 0-68 Sentence denotes Neuroimaging findings of brain MRI and CT in patients with COVID-19:
T2 69-107 Sentence denotes A systematic review and meta-analysis.
T3 108-116 Sentence denotes PURPOSE:
T4 117-262 Sentence denotes To comprehensively evaluate the incidences of abnormal neuroimaging findings in patients with COVID-19 via a systematic review and meta-analysis.
T5 263-270 Sentence denotes METHOD:
T6 271-449 Sentence denotes PubMed-MEDLINE and EMBASE were searched for original articles reporting imaging findings of the brain in adult patients with COVID-19 between January 1, 2020 and October 9, 2020.
T7 450-656 Sentence denotes Abnormal neuroimaging findings were categorized as (1) cerebral microhemorrhages, (2) acute spontaneous intracranial hemorrhage (ICH), (3) acute to subacute infarcts, and (4) encephalitis or encephalopathy.
T8 657-744 Sentence denotes Pooled incidences of neuroimaging findings were assessed using random-effects modeling.
T9 745-865 Sentence denotes Between-study heterogeneity was explored by using the χ2 statistic for pooled incidences and the inconsistency index I2.
T10 866-972 Sentence denotes The quality of the studies was evaluated using the Risk of Bias Assessment Tool for Nonrandomized Studies.
T11 973-1068 Sentence denotes Subgroup meta-regression analysis was performed to identify potential sources of heterogeneity.
T12 1069-1077 Sentence denotes RESULTS:
T13 1078-1147 Sentence denotes Twenty-one eligible papers, including 2125 patients, were identified.
T14 1148-1447 Sentence denotes The pooled incidences of cerebral microhemorrhages, acute spontaneous ICH, acute/subacute infarcts, and encephalitis/encephalopathy were 6.9 % (95 % confidence interval [CI], 4.9 %-8.9 %), 5.4 % (95 % CI, 3.1 %-7.6 %), 24.0 % (95 % CI, 16.1 %-31.8 %), and 3.3 % (95 % CI, 1.9 %-4.7 %), respectively.
T15 1448-1534 Sentence denotes Substantial heterogeneities were noted for all neuroimaging findings (I2 = 87 %-97 %).
T16 1535-1604 Sentence denotes Significant publication biases were present in the pooled incidences.
T17 1605-1777 Sentence denotes In the subgroup meta-regression analysis, patients with mean or median ages over 65 years showed a significantly lower incidence of encephalitis/encephalopathy (P < 0.001).
T18 1778-1950 Sentence denotes Furthermore, studies reported that patients in ICU had significantly higher incidences of cerebral microhemorrhages (P < 0.001) and encephalitis/encephalopathy (P < 0.001).
T19 1951-1963 Sentence denotes CONCLUSIONS:
T20 1964-2067 Sentence denotes Considerable incidences of abnormal neuroimaging findings have been reported in patients with COVID-19.
T21 2068-2150 Sentence denotes Acute to subacute cerebral infarction was the most prevalent neuroimaging finding.