PubMed:33123093 JSONTXT 19 Projects

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Id Subject Object Predicate Lexical cue
T1 0-40 Sentence denotes The Impact of COVID-19 on Blood Glucose:
T2 41-79 Sentence denotes A Systematic Review and Meta-Analysis.
T3 80-91 Sentence denotes Background:
T4 92-293 Sentence denotes Diabetes mellitus is considered a common comorbidity of COVID-19, which has a wide spectrum of clinical manifestations ranging from asymptomatic infection to severe respiratory symptoms and even death.
T5 294-373 Sentence denotes However, the impact of COVID-19 on blood glucose has not been fully understood.
T6 374-499 Sentence denotes This meta-analysis aimed to summarize available data on the association between glycemic parameters and severity of COVID-19.
T7 500-508 Sentence denotes Methods:
T8 509-598 Sentence denotes PubMed, EMBASE, and Cochrane Library were searched from December 1, 2019 to May 15, 2020.
T9 599-752 Sentence denotes Observational studies investigating blood glucose or glycated hemoglobin A1c (HbA1c) according to the severity of COVID-19 were considered for inclusion.
T10 753-907 Sentence denotes Two independent researchers extracted data from eligible studies using a standardized data extraction sheet and then proceeded to cross check the results.
T11 908-1049 Sentence denotes Data were pooled using a fixed- or random-effects model to calculate the weighted mean differences (WMDs) and 95% confidence intervals (CIs).
T12 1050-1058 Sentence denotes Results:
T13 1059-1184 Sentence denotes Three studies reported blood glucose and HbA1c according to the severity of COVID-19 and were included in this meta-analysis.
T14 1185-1293 Sentence denotes The combined results showed that severe COVID-19 was associated with higher blood glucose (WMD 2.21, 95% CI:
T15 1294-1316 Sentence denotes 1.30-3.13, P < 0.001).
T16 1317-1511 Sentence denotes In addition, HbA1c was slightly higher in patients with severe COVID-19 than those with mild COVID-19, yet this difference did not reach significance (WMD 0.29, 95% CI: -0.59 to 1.16, P = 0.52).
T17 1512-1524 Sentence denotes Conclusions:
T18 1525-1626 Sentence denotes This meta-analysis provides evidence that severe COVID-19 is associated with increased blood glucose.
T19 1627-1745 Sentence denotes This highlights the need to effectively monitor blood glucose to improve prognosis in patients infected with COVID-19.