Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-81 |
Sentence |
denotes |
Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series. |
T2 |
82-93 |
Sentence |
denotes |
Background: |
T3 |
94-204 |
Sentence |
denotes |
Novel coronavirus-19 disease (COVID-19) is associated with significant cardiovascular morbidity and mortality. |
T4 |
205-299 |
Sentence |
denotes |
To date, there have not been reports of sinus node dysfunction (SND) associated with COVID-19. |
T5 |
300-447 |
Sentence |
denotes |
This case series describes clinical characteristics, potential mechanisms, and short-term outcomes of COVID-19 patients who experience de novo SND. |
T6 |
448-461 |
Sentence |
denotes |
Case summary: |
T7 |
462-545 |
Sentence |
denotes |
We present two cases of new-onset SND in patients recently diagnosed with COVID-19. |
T8 |
546-827 |
Sentence |
denotes |
Patient 1 is a 70-year-old female with no major past medical history who was intubated for acute hypoxic respiratory failure secondary to COVID-19 pneumonia and developed new-onset sinus bradycardia without a compensatory increase in heart rate in response to relative hypotension. |
T9 |
828-1183 |
Sentence |
denotes |
Patient 2 is an 81-year-old male with a past medical history of an ascending aortic aneurysm, hypertension, and obstructive sleep apnoea who required intubation for COVID-19-induced acute hypoxic respiratory failure and exhibited new-onset sinus bradycardia followed by numerous episodes of haemodynamically significant accelerated idioventricular rhythm. |
T10 |
1184-1264 |
Sentence |
denotes |
Two weeks following the onset of SND, both patients remain in sinus bradycardia. |
T11 |
1265-1335 |
Sentence |
denotes |
Discussion: COVID-19-associated SND has not previously been described. |
T12 |
1336-1456 |
Sentence |
denotes |
The potential mechanisms for SND in patients with COVID-19 include myocardial inflammation or direct viral infiltration. |
T13 |
1457-1586 |
Sentence |
denotes |
Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability. |