| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-68 |
Sentence |
denotes |
Research progress and challenges to coronavirus vaccine development. |
| T2 |
69-181 |
Sentence |
denotes |
Coronaviruses (CoVs) are non-segmented, single-stranded, positive-sense RNA viruses highly pathogenic to humans. |
| T3 |
182-292 |
Sentence |
denotes |
Some CoVs are known to cause respiratory and intestinal diseases, posing a threat to the global public health. |
| T4 |
293-403 |
Sentence |
denotes |
Against this backdrop, it is of critical importance to develop safe and effective vaccines against these CoVs. |
| T5 |
404-598 |
Sentence |
denotes |
This review discusses human vaccine candidates in any stage of development and explores the viral characteristics, molecular epidemiology, and immunology associated with CoV vaccine development. |
| T6 |
599-827 |
Sentence |
denotes |
At present, there are many obstacles and challenges to vaccine research and development, including the lack of knowledge about virus transmission, pathogenesis, and immune response, absence of the most appropriate animal models. |
| T7 |
828-867 |
Sentence |
denotes |
This article is protected by copyright. |
| T8 |
868-888 |
Sentence |
denotes |
All rights reserved. |
