LitCovid-sentences  

PubMed:32830267 JSONTXT 15 Projects

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Id Subject Object Predicate Lexical cue
T1 0-119 Sentence denotes Incidence, Clinical Characteristics, and Evolution of SARS-CoV-2 Infection in Patients With Inflammatory Bowel Disease:
T2 120-159 Sentence denotes A Single-Center Study in Madrid, Spain.
T3 160-171 Sentence denotes BACKGROUND:
T4 172-271 Sentence denotes There are scarce data about SARS-CoV-2 infection in patients with inflammatory bowel disease (IBD).
T5 272-391 Sentence denotes Our aim was to analyze the incidence, clinical presentation, and severity of SARS-CoV-2 infection in patients with IBD.
T6 392-400 Sentence denotes METHODS:
T7 401-448 Sentence denotes This is a cross-sectional, observational study.
T8 449-642 Sentence denotes We contacted all the patients being treated at our IBD unit to identify those patients with suspected or confirmed SARS-CoV-2 infection, following the World Health Organization case definition.
T9 643-725 Sentence denotes Data were obtained by patient electronical medical records and by phone interview.
T10 726-734 Sentence denotes RESULTS:
T11 735-934 Sentence denotes Eighty-two of 805 patients with IBD (10.2%; 95% confidence interval [CI], 8.3-12.5) were diagnosed as having confirmed (28 patients, 3.5%; 95% CI, 2.4-5.0) or suspected (54 patients, 6.7%) infection.
T12 935-1077 Sentence denotes Patient age was 46 ± 14 years, 44 patients were female (53.7%), 17.3% were smokers, 51.2% had Crohn disease (CD), and 39.0% had comorbidities.
T13 1078-1176 Sentence denotes Digestive symptoms were reported in 41 patients (50.0%), with diarrhea as the most common (42.7%).
T14 1177-1256 Sentence denotes One patient (1.2%) was diagnosed with IBD flare-up during SARS-CoV-2 infection.
T15 1257-1351 Sentence denotes Twenty-two patients (26.8%) temporarily withdrew from their IBD treatment because of COVID-19.
T16 1352-1425 Sentence denotes Most of the patients had mild disease (79.3%), and 1 patient died (1.2%).
T17 1426-1675 Sentence denotes In the multivariate analysis, the presence of dyspnea was associated with moderate to severe infection (odds ratio, 5.3; 95% CI, 1.6-17.7; P = 0.01) and myalgias (odds ratio, 4.8; 95% CI, 1.3-17.9; P = 0.02) were related to a milder clinical course.
T18 1676-1722 Sentence denotes Immunosuppression was not related to severity.
T19 1723-1790 Sentence denotes CONCLUSIONS: SARS-CoV-2 infection in patients with IBD is not rare.
T20 1791-1842 Sentence denotes Dyspnea is associated with a more severe infection.
T21 1843-2030 Sentence denotes Therapy for IBD, including immunomodulators and biologic therapy, is not related to a greater severity of COVID-19, and SARS-CoV-2 infections do not appear to be related to IBD flare-ups.