PubMed:32784110 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-60 Sentence denotes Analysis of cardiopulmonary findings in COVID-19 fatalities:
T2 61-143 Sentence denotes High incidence of pulmonary artery thrombi and acute suppurative bronchopneumonia.
T3 144-346 Sentence denotes Since its recognition in December 2019, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has rapidly spread globally causing a pandemic that represents the greatest medical challenge in decades.
T4 347-515 Sentence denotes The aim of the study was to evaluate the spectrum of cardiopulmonary pathology of COVID-19 based on (non-minimal invasive) autopsies performed on 14 COVID-19 decedents.
T5 516-582 Sentence denotes Bilateral diffuse alveolar damage (DAD) was found in all patients.
T6 583-718 Sentence denotes Superimposed acute bronchopneumonia was present in 11 of 14 (78.6%) patients and was considered the major cause of death in 2 patients.
T7 719-799 Sentence denotes A key finding was the presence of thrombotic/thromboembolic vascular occlusions.
T8 800-843 Sentence denotes We classified 5 types of pulmonary thrombi:
T9 844-1238 Sentence denotes 1. capillary microthrombi (11/14, 78.6%); 2. partially organized thrombi in mid-sized pulmonary arteries with complete vessel occlusion; 3. non-organized thrombi in mid-sized pulmonary arteries that did not completely fill out the vessel lumen and probably represented thromboemboli rather than thrombosis; 4. bone marrow emboli (1/14, 7.1%); and 5. septic pulmonary thromboemboli (1/14, 7.1%).
T10 1239-1376 Sentence denotes Pulmonary thrombi in mid-sized arteries were noted in 5 of 14 (35.7%) patients, causing pulmonary infarction and/or pulmonary hemorrhage.
T11 1377-1585 Sentence denotes All patients had evidence of chronic cardiac disease, including myocardial hypertrophy (13/14, 92.9%), mild to marked coronary artery atherosclerosis (14/14, 100%) and focal myocardial fibrosis (3/14, 21.4%).
T12 1586-1804 Sentence denotes Acute myocardial infarction was found as concurrent cause of death in 3 (21.4%) patients, and significant cardiac hypertrophy (heart weight 750 g) was present in 1 (7.1%) patient with ATTR-positive cardiac amyloidosis.
T13 1805-2041 Sentence denotes The autopsy findings confirm that COVID-19 is a systemic disease, with major involvement of the lungs, that increases the risk of cardiac and vascular complications including acute myocardial injury and thrombotic/thromboembolic events.
T14 2042-2162 Sentence denotes Secondary acute bronchopneumonia is a common complication in patients with COVID-19 and may be the major cause of death.