PubMed:32656939 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T1 0-66 Sentence denotes Lessons from dermatology about inflammatory responses in Covid-19.
T2 67-219 Sentence denotes The SARS-Cov-2 is a single-stranded RNA virus composed of 16 non-structural proteins (NSP 1-16) with specific roles in the replication of coronaviruses.
T3 220-314 Sentence denotes NSP3 has the property to block host innate immune response and to promote cytokine expression.
T4 315-428 Sentence denotes NSP5 can inhibit interferon (IFN) signalling and NSP16 prevents MAD5 recognition, depressing the innate immunity.
T5 429-528 Sentence denotes Dendritic cells, monocytes, and macrophages are the first cell lineage against viruses' infections.
T6 529-613 Sentence denotes The IFN type I is the danger signal for the human body during this clinical setting.
T7 614-776 Sentence denotes Protective immune responses to viral infection are initiated by innate immune sensors that survey extracellular and intracellular space for foreign nucleic acids.
T8 777-886 Sentence denotes In Covid-19 the pathogenesis is not yet fully understood, but viral and host factors seem to play a key role.
T9 887-1191 Sentence denotes Important points in severe Covid-19 are characterized by an upregulated innate immune response, hypercoagulopathy state, pulmonary tissue damage, neurological and/or gastrointestinal tract involvement, and fatal outcome in severe cases of macrophage activation syndrome, which produce a 'cytokine storm'.
T10 1192-1505 Sentence denotes These systemic conditions share polymorphous cutaneous lesions where innate immune system is involved in the histopathological findings with acute respiratory distress syndrome, hypercoagulability, hyperferritinemia, increased serum levels of D-dimer, lactic dehydrogenase, reactive-C-protein and serum A amyloid.
T11 1506-1843 Sentence denotes It is described that several polymorphous cutaneous lesions similar to erythema pernio, urticarial rashes, diffuse or disseminated erythema, livedo racemosa, blue toe syndrome, retiform purpura, vesicles lesions, and purpuric exanthema or exanthema with clinical aspects of symmetrical drug-related intertriginous and flexural exanthema.
T12 1844-1938 Sentence denotes This review describes the complexity of Covid-19, its pathophysiological and clinical aspects.