LitCovid-sentences  

PubMed:32610873 JSONTXT 23 Projects

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Id Subject Object Predicate Lexical cue
T1 0-123 Sentence denotes Characteristics, Treatment Outcomes and Role of Hydroxychloroquine among 522 COVID-19 hospitalized patients in Jaipur City:
T2 124-151 Sentence denotes An Epidemio-Clinical Study.
T3 152-160 Sentence denotes Purpose:
T4 161-406 Sentence denotes The present study was undertaken to investigate epidemiological distribution, clinical manifestation, co morbid status, treatment strategy and case fatality index of emerging COVID-19 infection at SMS Medical College Hospital, Jaipur, Rajasthan.
T5 407-588 Sentence denotes It also evaluated efficacy of hydroxychloroquine (HCQ) in treatment of patients and risk of serious adverse outcomes in patients with COVID-19 in relation to their co morbid status.
T6 589-611 Sentence denotes Materials and methods:
T7 612-780 Sentence denotes In an attempt to provide extensive information pertaining to epidemiological and clinical characteristics of COVID-19, the present study was undertaken on 522 patients.
T8 781-966 Sentence denotes The patients were COVID-19 confirmed positive by genomic analysis through Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) at SMS Medical College and Attached Hospitals, Jaipur.
T9 967-1244 Sentence denotes The indoor admitted patient's information inclusive of demographic profile (age, sex, nationality, residence), date of confirmation for positive COVID-19 case, travel/ exposure history, date of recovery/ death, clinical features, co morbidities and treatment plan was recorded.
T10 1245-1357 Sentence denotes A serial follow-up of recovered patients to evaluate infective period of the disease was also part of the study.
T11 1358-1366 Sentence denotes Results:
T12 1367-1478 Sentence denotes A total of 522 patients of laboratory confirmed COVID-19 test by RT-PCR at SMS Hospitals, Jaipur were assessed.
T13 1479-1586 Sentence denotes Among the confirmed cases, most of patients were young adult in the age group with mean age of 35.42 years.
T14 1587-1775 Sentence denotes 22.41% patients were below 20 years of age, majority of patients (58.80%) were in the age range of 21 to 50 years and only 18.79% patient population was in the age range of above 50 years.
T15 1776-1885 Sentence denotes Females (39.08%) were affected less than males (60.91%) with an average sex ratio of female: male being 0.64.
T16 1886-2284 Sentence denotes Out of the total analyzed patients, only 24.32% patients were symptomatic, among them fever (55.90%), cough (52.75%), sore throat (49.60%) and shortness of breath (46.45%) were the most common presenting clinical manifestations while a few patients also had symptoms of headache (26.77%), chest pain (6.29%) and other symptoms (7.87%) like pain abdomen, fatigue, joints pain, altered sensorium etc.
T17 2285-2343 Sentence denotes Most of symptomatic patients belonging to older age group.
T18 2344-2493 Sentence denotes An average of 40.40% patient population of above 50 years of age, were symptomatic while none of the patients below 10 years of age were symptomatic.
T19 2494-2561 Sentence denotes 13.98% patients had some or the other underlying co morbid disease.
T20 2562-2862 Sentence denotes The most prevalent co morbidity was hypertension (42.46%) followed by Diabetes mellitus (39.72%), Old k-chest (20.54%), COPD/ Bronchial Asthma (16.43%), Coronary artery disease (13.69%), Chronic kidney disease (13.69%) and Valvular heart disease (6.84%) distributed in co morbid patients of COVID-19.
T21 2863-3050 Sentence denotes 60.27% of patient population with underlying co morbid conditions were more prone to develop symptomatology complex as compared to that observed in patients with no co morbidity (18.42%).
T22 3051-3134 Sentence denotes 116 patients had recovered with effective treatment till the date of data analysis.
T23 3135-3310 Sentence denotes Time of recovery was counted from the date of positive report to 1st negative report of oropharyngeal sample by RT-PCR for COVID-19 with an average recovery time of 8.15 days.
T24 3311-3482 Sentence denotes 23.27% patients recovered within 5 days, while 52.58% patients took about 6-10 days, 23.27% patients took 11-15 days and remaining 0.86% took more than 16 days to recover.
T25 3483-3635 Sentence denotes In the present study 15 patients had died till analysis of data, among the deceased, 73.33% were above 50 year of age with a male preponderance (66.6%).
T26 3636-3779 Sentence denotes Interestingly, all deceased (100%) had presented with clinical manifestations of COVID-19 and all had underlying multiple co morbid conditions.
T27 3780-3900 Sentence denotes Majority of patients had early mortality after admission to hospital with two third death account in initial three days.
T28 3901-4145 Sentence denotes Asymptomatic patients (cases) treated with HCQ recovered early (average recovery time =5.4 days) compared to asymptomatic patients who did not receive any treatment (control group) and had longer recovery time (average recovery time =7.6 days).
T29 4146-4157 Sentence denotes Conclusion:
T30 4158-4259 Sentence denotes The varied spectra of COVID-19 mostly affects young adult age group (third to fifth decades of life).
T31 4260-4388 Sentence denotes Interestingly, early age group was also affected in significant proportion when compared with similar data from other countries.
T32 4389-4474 Sentence denotes It was observed that male population seemed to be was more prone to getting infected.
T33 4475-4662 Sentence denotes Majority of COVID-19 positive patients (nearly three-fourth) were asymptomatic (mostly in young age range) at the time of diagnosis, which poses a major challenge for health care workers.
T34 4663-4782 Sentence denotes Fever, cough, sore throat and shortness of breath were major symptoms that could be detected in such COVID-19 patients.
T35 4783-4858 Sentence denotes Symptomatic clinical manifestations were more common in old age population.
T36 4859-4991 Sentence denotes Infectivity was higher in patients that had underlying co morbid disease, especially in patients with multiple co morbid conditions.
T37 4992-5090 Sentence denotes Symptomatic presentation of COVID-19 was observed to be higher in patients with co morbid disease.
T38 5091-5163 Sentence denotes Average recovery time from COVID-19 was 8 days with effective treatment.
T39 5164-5313 Sentence denotes Mortality in COVID-19 was higher in old age population, male gender, symptomatic and co morbid patients as compared to other similarly matched group.
T40 5314-5443 Sentence denotes Most of mortality was noted within first few days of admission, suggestive of early mortality due to the primary disease process.
T41 5444-5536 Sentence denotes Treatment with HCQ had early recovery without effectively influencing the overall mortality.