PubMed:32164424 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-9 Sentence denotes COVID-19:
T2 10-198 Sentence denotes An Update on the Epidemiological, Clinical, Preventive and Therapeutic Evidence and Guidelines of Integrative Chinese-Western Medicine for the Management of 2019 Novel Coronavirus Disease.
T3 199-319 Sentence denotes As of 22 February 2020, more than 77662 cases of confirmed COVID-19 have been documented globally with over 2360 deaths.
T4 320-589 Sentence denotes Common presentations of confirmed cases include fever, fatigue, dry cough, upper airway congestion, sputum production, shortness of breath, myalgia/arthralgia with lymphopenia, prolonged prothrombin time, elevated C-reactive protein, and elevated lactate dehydrogenase.
T5 590-766 Sentence denotes The reported severe/critical case ratio is approximately 7-10% and median time to intensive care admission is 9.5-10.5 days with mortality of around 1-2% varied geographically.
T6 767-1049 Sentence denotes Similar to outbreaks of other newly identified virus, there is no proven regimen from conventional medicine and most reports managed the patients with lopinavir/ritonavir, ribavirin, beta-interferon, glucocorticoid and supportive treatment with remdesivir undergoing clinical trial.
T7 1050-1178 Sentence denotes In China, Chinese medicine is proposed as a treatment option by national and provincial guidelines with substantial utilization.
T8 1179-1356 Sentence denotes We reviewed the latest national and provincial clinical guidelines, retrospective cohort studies, and case series regarding the treatment of COVID-19 by add-on Chinese medicine.
T9 1357-1596 Sentence denotes We have also reviewed the clinical evidence generated from SARS and H1N1 management with hypothesized mechanisms and latest in silico findings to identify candidate Chinese medicines for the consideration of possible trials and management.
T10 1597-1787 Sentence denotes Given the paucity of strongly evidence-based regimens, the available data suggest that Chinese medicine could be considered as an adjunctive therapeutic option in the management of COVID-19.