PMC:7799378 / 17903-18682 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T148 0-102 Sentence denotes NET formation can be inhibited by NAC and DPI, indicating the involvement of oxidative stress and NOX.
T149 103-211 Sentence denotes A metabolic shift towards the PPP is required for the NET formation induced by amyloid fibrils and PMA [93].
T150 212-326 Sentence denotes G6PD-derived NADPH can serve as a substrate for NOX, which generates superoxide and stimulates NET formation [17].
T151 327-464 Sentence denotes Neutrophils from individuals with the G6PD Taiwan-Hakka variant are equally effective as normal individuals regarding NET formation [94].
T152 465-591 Sentence denotes However, defective NET formation and NOX activity are observed in neutrophils of individuals with severe G6PD deficiency [95].
T153 592-700 Sentence denotes The absence of NET formation is found in NOX deficiency associated with chronic granulomatous disease (CGD).
T154 701-779 Sentence denotes Severe G6PD deficiency may mimic impaired NOX resulting in dysfunctional NETs.