PMC:7799378 / 12080-13709 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T100 0-118 Sentence denotes Vitamin C, a natural antioxidant and potent free radical scavenger, has long been known for its antiviral effect [60].
T101 119-242 Sentence denotes The capacity for donating electrons enables vitamin C to support essential cellular processes and immune responses [61–64].
T102 243-381 Sentence denotes Vitamin C maintains barrier integrity and facilitates wound healing of the skin against oxidative stress and microbial infections [65,66].
T103 382-481 Sentence denotes Vitamin C is required for chemotaxis, phagocytosis, and microbial clearance in neutrophils [67,68].
T104 482-616 Sentence denotes It is also necessary for apoptosis and clearance of used neutrophils as well as neutrophil extracellular trap (NET) formation [69,70].
T105 617-706 Sentence denotes The acidic condition caused by vitamin C helps to convert inorganic nitrate into NO [71].
T106 707-784 Sentence denotes Lack of vitamin C leads to immune dysfunction and vulnerability to infection.
T107 785-865 Sentence denotes Humans cannot produce vitamin C owing to nonfunctional L-gluconolactone oxidase.
T108 866-973 Sentence denotes Supplementation with a high dose of vitamin C can reduce the symptoms and duration of the common cold [72].
T109 974-1149 Sentence denotes Vitamin C therapy is recognized as a beneficial adjunctive strategy to ameliorate the symptoms of respiratory diseases, including severe acute respiratory disease (SARS) [73].
T110 1150-1273 Sentence denotes Glucose competes with the uptake of the oxidized form of vitamin C, dehydroascorbic acid, via the glucose transporter [74].
T111 1274-1349 Sentence denotes Hence, the bioavailability of vitamin C can be restricted by hyperglycemia.
T112 1350-1509 Sentence denotes If diabetic COVID-19 patients have low levels of vitamin C and are not treated with intravenous vitamin C, it may partly explain the severity of their illness.
T113 1510-1629 Sentence denotes Several clinical trials have been proposed to infuse high dose vitamin C as an intervention for COVID-19 patients [75].