PMC:7799377 / 21843-22778 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T147 0-155 Sentence denotes The expression of ACE-2 receptor cells and DPP4 are very low in the CNS [64], and the route by which coronaviruses enter the CNS is subject to speculation.
T148 156-310 Sentence denotes It has been suggested that they invade peripheral nerve terminals first, and, in that way, enter onto a synapse-connected pathway into the CNS [23,65–67].
T149 311-471 Sentence denotes This so-called ‘trans-synaptic transfer’ has been observed for other lesser-known coronaviruses, such as HEV67N and the avian bronchitis virus [10,23,65,67,68].
T150 472-706 Sentence denotes Indeed, the HEV67N virus has been demonstrated in porcine studies to invade the brain; first, it infects the nasal mucosa, lungs, and small intestines and then peripheral nerves transport it retrogradely to the medullary neurons [66].
T151 707-806 Sentence denotes The avian bronchitis virus infects the brainstem of mice and may cause neuroanatomical disruptions.
T152 807-935 Sentence denotes The mice that died of respiratory failure may have had failure of the cardiorespiratory center within the brain stem [23,64,69].