Id |
Subject |
Object |
Predicate |
Lexical cue |
T74 |
0-35 |
Sentence |
denotes |
Middle eastern respiratory syndrome |
T75 |
36-189 |
Sentence |
denotes |
MERS was first identified in September 2012 in a 60-year-old man in Jeddah, Saudi Arabia, who presented with pneumonia complicated by renal failure [31]. |
T76 |
190-351 |
Sentence |
denotes |
Sporadic cases were reported outside of the Middle East up until 2015, when an outbreak in South Korea occurred with 186 confirmed infections and 38 deaths [32]. |
T77 |
352-493 |
Sentence |
denotes |
MERS has established associations with encephalomyelitis, vasculitis, Guillain-Barré syndrome (GBS), and encephalitis of the brain stem [21]. |
T78 |
494-647 |
Sentence |
denotes |
The clinical course of MERS ranges from asymptomatic cases (about 4%) to severe pneumonia with multiorgan involvement and negative patient outcomes [15]. |
T79 |
648-818 |
Sentence |
denotes |
While pulmonary, gastrointestinal, renal, and hematological complications have been reported in MERS patients, there are fewer reports of neurological complications [15]. |
T80 |
819-911 |
Sentence |
denotes |
In fact, the MERS-CoV virus has never been isolated from neural tissue in human beings [28]. |
T81 |
912-1134 |
Sentence |
denotes |
In a study of 737 hospitalized MERS patients in South Korea, the most commonly reported symptoms were respiratory symptoms (13.6%), fever (11.1%), fatigue (11.1%), myalgia (9.2%), and gastrointestinal symptoms (7.5%) [32]. |
T82 |
1135-1271 |
Sentence |
denotes |
In a study of 23 MERS patients from South Korea, 17.4% experienced neurological symptoms either during or following MERS treatment [33]. |
T83 |
1272-1384 |
Sentence |
denotes |
These neurological complications occurred about two to three weeks after the onset of respiratory symptoms [33]. |
T84 |
1385-1507 |
Sentence |
denotes |
A study from Saudi Arabia (n = 70) reported that 24.7% of MERS patients experienced confusion and 8.6% had a seizure [34]. |
T85 |
1508-1609 |
Sentence |
denotes |
In this study, fever was present in 61.4% of patients, dyspnea occurred in 60%, an 54.3% had a cough. |
T86 |
1610-1749 |
Sentence |
denotes |
MERS symptoms were typically severe with 70% of those hospitalized in this study requiring intensive care and 60% of this cohort died [34]. |
T87 |
1750-1927 |
Sentence |
denotes |
The literature reports a fatal case of a 34-year-old woman with diabetes hospitalized for MERS, who two weeks after diagnosis developed a headache with nausea and vomiting [15]. |
T88 |
1928-2170 |
Sentence |
denotes |
An urgent computed tomography scan showed right frontal lobe intracerebral hemorrhage with massive brain edema; laboratory findings showed disseminated intravascular coagulation, including thrombocytopenia and a prolonged coagulation profile. |
T89 |
2171-2353 |
Sentence |
denotes |
In another case, a 28-year-old man was hospitalized in the intensive care unit for MERS complicated by bacterial pneumonia and had to be put on a ventilator for respiratory distress. |
T90 |
2354-2482 |
Sentence |
denotes |
Unfortunately, after initial improvement, he reported weakness and tingling in his legs that made it impossible for him to walk. |
T91 |
2483-2650 |
Sentence |
denotes |
Using neuroimaging scans, cerebrospinal fluid analysis, nerve conduction velocity studies, and spinal imaging, a diagnosis was made of critical-illness polyneuropathy. |
T92 |
2651-2822 |
Sentence |
denotes |
He was treated with intravenous (IV) immunoglobulin 400 mg/kg daily for five days and was discharged in 40 days; gradual improvement was noted over the next 6 months [15]. |