PMC:7797241 / 19460-23153 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T130 0-19 Sentence denotes Results and outputs
T131 20-231 Sentence denotes From 100 000 simulated parameter sets, we selected the best 100 baseline model fits on the basis of agreement to the calibration data on daily confirmed COVID-19 cases and weekly mortality due to COVID-19 in SW.
T132 232-319 Sentence denotes The distribution of the best fitting values is shown in online supplemental figure S1A.
T133 320-387 Sentence denotes All results are shown with median and 95% credible intervals (CrI).
T134 388-620 Sentence denotes On 11 May 2020, the reported cumulative number of individuals with (laboratory confirmed) COVID-19 was 7116 in SW,14 and the most recent report on total cumulative deaths showed that 2306 had died from COVID-19 (as of 8 May 2020).25
T135 622-688 Sentence denotes Estimating the total proportion of individuals with COVID-19 in SW
T136 689-858 Sentence denotes Figure 2 shows the projected numbers of exposed, recovered and infectious (asymptomatic and symptomatic infections) until lockdown measures were lessened on 11 May 2020.
T137 859-1013 Sentence denotes On this date, the model predicts that a total of 5793 (95% CrI 2003 to 12 051) were infectious (0.10% of the total SW population, 95% CrI 0.04% to 0.22%).
T138 1014-1280 Sentence denotes The model also predicts that a total of 189 048 (95% CrI 141 580 to 277 955) have had the virus but recovered (either asymptomatically or symptomatically), which is 3.4% (95% CrI 2.5% to 5.0%) of the SW population (not infectious and not susceptible to reinfection).
T139 1281-1495 Sentence denotes Figure 2 The predicted median size of the exposed (E), infectious (I) and recovered (R) classes, along with the size of asymptomatic and symptomatic individuals on each day in South West England until 11 May 2020.
T140 1496-1630 Sentence denotes Blue and red vertical lines represent the date the government introduced social distancing and school closures/lockdown, respectively.
T141 1632-1709 Sentence denotes Estimating the total hospitalised patients with COVID-19 in acute and IC beds
T142 1710-1949 Sentence denotes The total number of patients in acute (non-IC) hospital beds across SW was projected to be 701 (95% CrI 169 to 1543) and the total number of patients in IC hospital beds was projected to be 110 (95% CrI 8 to 464) on 11 May 2020 (figure 3).
T143 1950-2088 Sentence denotes Note that these ranges are quite large due to the uncertainty in the data and as more data become available these predictions will change.
T144 2089-2227 Sentence denotes Figure 3 The predicted number of hospitalised patients in acute and intensive care beds in the South West England (SW) until 11 May 2020.
T145 2228-2460 Sentence denotes The number of daily incoming patients diagnosed with COVID-19 is shown in orange (from SW daily case data14), 95% credible intervals are shown in light grey, 50% in dark grey and the median value of the fits is highlighted in black.
T146 2461-2531 Sentence denotes The shaded region indicates the prediction of the model from the data.
T147 2532-2666 Sentence denotes Blue and red vertical lines represent the date the government introduced social distancing and school closures/lockdown, respectively.
T148 2667-2686 Sentence denotes IC, intensive care.
T149 2688-2742 Sentence denotes Estimating the reproduction number under interventions
T150 2743-2878 Sentence denotes Figure 4 shows the model prediction for the reproduction (‘R’) number over time until 11 May 2020, when lockdown measures were relaxed.
T151 2879-3018 Sentence denotes All interventions (social distancing, school closures/lockdown) had a significant impact on the reproductive number for COVID-19 in the SW.
T152 3019-3184 Sentence denotes We predict that prior to any interventions R was 2.6 (95% CrI 2.0 to 3.2), and the introduction of social distancing reduced this number to 2.3 (95% CrI 1.8 to 2.9).
T153 3185-3340 Sentence denotes At the minimum, R was 0.6 (95% CrI 0.5 to 0.7) after all prior interventions were enacted and adhered to (social distancing, school closures and lockdown).
T154 3341-3434 Sentence denotes Figure 4 The effect of interventions on estimates of R (y-axis) over time until 11 May 2020.
T155 3435-3693 Sentence denotes Additional results for the fitting performance of the model (online supplemental figure S2A, B and table S2), the performance based on prior data (online supplemental figure S3A–D) and sensitivity analysis can be found in the online supplemental information.