Id |
Subject |
Object |
Predicate |
Lexical cue |
T130 |
0-19 |
Sentence |
denotes |
Results and outputs |
T131 |
20-231 |
Sentence |
denotes |
From 100 000 simulated parameter sets, we selected the best 100 baseline model fits on the basis of agreement to the calibration data on daily confirmed COVID-19 cases and weekly mortality due to COVID-19 in SW. |
T132 |
232-319 |
Sentence |
denotes |
The distribution of the best fitting values is shown in online supplemental figure S1A. |
T133 |
320-387 |
Sentence |
denotes |
All results are shown with median and 95% credible intervals (CrI). |
T134 |
388-620 |
Sentence |
denotes |
On 11 May 2020, the reported cumulative number of individuals with (laboratory confirmed) COVID-19 was 7116 in SW,14 and the most recent report on total cumulative deaths showed that 2306 had died from COVID-19 (as of 8 May 2020).25 |
T135 |
622-688 |
Sentence |
denotes |
Estimating the total proportion of individuals with COVID-19 in SW |
T136 |
689-858 |
Sentence |
denotes |
Figure 2 shows the projected numbers of exposed, recovered and infectious (asymptomatic and symptomatic infections) until lockdown measures were lessened on 11 May 2020. |
T137 |
859-1013 |
Sentence |
denotes |
On this date, the model predicts that a total of 5793 (95% CrI 2003 to 12 051) were infectious (0.10% of the total SW population, 95% CrI 0.04% to 0.22%). |
T138 |
1014-1280 |
Sentence |
denotes |
The model also predicts that a total of 189 048 (95% CrI 141 580 to 277 955) have had the virus but recovered (either asymptomatically or symptomatically), which is 3.4% (95% CrI 2.5% to 5.0%) of the SW population (not infectious and not susceptible to reinfection). |
T139 |
1281-1495 |
Sentence |
denotes |
Figure 2 The predicted median size of the exposed (E), infectious (I) and recovered (R) classes, along with the size of asymptomatic and symptomatic individuals on each day in South West England until 11 May 2020. |
T140 |
1496-1630 |
Sentence |
denotes |
Blue and red vertical lines represent the date the government introduced social distancing and school closures/lockdown, respectively. |
T141 |
1632-1709 |
Sentence |
denotes |
Estimating the total hospitalised patients with COVID-19 in acute and IC beds |
T142 |
1710-1949 |
Sentence |
denotes |
The total number of patients in acute (non-IC) hospital beds across SW was projected to be 701 (95% CrI 169 to 1543) and the total number of patients in IC hospital beds was projected to be 110 (95% CrI 8 to 464) on 11 May 2020 (figure 3). |
T143 |
1950-2088 |
Sentence |
denotes |
Note that these ranges are quite large due to the uncertainty in the data and as more data become available these predictions will change. |
T144 |
2089-2227 |
Sentence |
denotes |
Figure 3 The predicted number of hospitalised patients in acute and intensive care beds in the South West England (SW) until 11 May 2020. |
T145 |
2228-2460 |
Sentence |
denotes |
The number of daily incoming patients diagnosed with COVID-19 is shown in orange (from SW daily case data14), 95% credible intervals are shown in light grey, 50% in dark grey and the median value of the fits is highlighted in black. |
T146 |
2461-2531 |
Sentence |
denotes |
The shaded region indicates the prediction of the model from the data. |
T147 |
2532-2666 |
Sentence |
denotes |
Blue and red vertical lines represent the date the government introduced social distancing and school closures/lockdown, respectively. |
T148 |
2667-2686 |
Sentence |
denotes |
IC, intensive care. |
T149 |
2688-2742 |
Sentence |
denotes |
Estimating the reproduction number under interventions |
T150 |
2743-2878 |
Sentence |
denotes |
Figure 4 shows the model prediction for the reproduction (‘R’) number over time until 11 May 2020, when lockdown measures were relaxed. |
T151 |
2879-3018 |
Sentence |
denotes |
All interventions (social distancing, school closures/lockdown) had a significant impact on the reproductive number for COVID-19 in the SW. |
T152 |
3019-3184 |
Sentence |
denotes |
We predict that prior to any interventions R was 2.6 (95% CrI 2.0 to 3.2), and the introduction of social distancing reduced this number to 2.3 (95% CrI 1.8 to 2.9). |
T153 |
3185-3340 |
Sentence |
denotes |
At the minimum, R was 0.6 (95% CrI 0.5 to 0.7) after all prior interventions were enacted and adhered to (social distancing, school closures and lockdown). |
T154 |
3341-3434 |
Sentence |
denotes |
Figure 4 The effect of interventions on estimates of R (y-axis) over time until 11 May 2020. |
T155 |
3435-3693 |
Sentence |
denotes |
Additional results for the fitting performance of the model (online supplemental figure S2A, B and table S2), the performance based on prior data (online supplemental figure S3A–D) and sensitivity analysis can be found in the online supplemental information. |