| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T99 |
0-6 |
Sentence |
denotes |
3.2.2. |
| T100 |
7-33 |
Sentence |
denotes |
Functional Efficacy Assays |
| T101 |
34-164 |
Sentence |
denotes |
Measurementent of the efficacy of the compound on the B2 receptor was carried out following the protocol described elsewhere [31]. |
| T102 |
165-347 |
Sentence |
denotes |
The method is based on measuring differences in intracellular Ca2+ concentrations produced in diverse conditions on CHO cells expressing recombinant human B2 receptor by fluorometry. |
| T103 |
348-468 |
Sentence |
denotes |
Agonism was measured through the capacity of the compound to increase Ca2+ concentration compared to BK (EC50 ~ 2.4 pM). |
| T104 |
469-576 |
Sentence |
denotes |
Antagonism was measured through the capacity to antagonize BK based on the reduction of Ca2+ concentration. |
