| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T95 |
0-166 |
Sentence |
denotes |
Raloxifene was tested for its ability to displace reference ligands on human recombinant bradykinin B1 or B2 receptors, respectively, expressed in CHO cells at 20 µM. |
| T96 |
167-375 |
Sentence |
denotes |
For this purpose, first saturation isotherms were obtained with reference ligands ([3H] des-Arg10-BK (0.35 nM) in the case of B1, and [3H]-bradykinin (0.2 nM) for B2) incubated for 60 min at room temperature. |
| T97 |
376-509 |
Sentence |
denotes |
Nonspecific binding was evaluated by adding a reference compound (desArg9[Leu8]-BK at 10 µM in the case of B1 and BK at 1 µM for B2). |
| T98 |
510-742 |
Sentence |
denotes |
Antagonism of raloxifene was measured as a percent inhibition of specific binding of [3H]-bradykinin as control, obtained in the presence of raloxifene at 20 µM and using as reference compounds desArg10-KD for B1 and NPC-567 for B2. |
