LitCovid-sentences  

PMC:7796041 / 24572-26166 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T204 0-200 Sentence denotes With respect to risk factors for arrhythmia incidence during hospitalization for COVID-19, we could identify age and previous cardiovascular disease as predictors for the occurrence of any arrhythmia.
T205 201-383 Sentence denotes These baseline characteristics have previously been shown to predispose for the development of arrhythmia in the general population without association with infectious diseases [24].
T206 384-488 Sentence denotes Thus, they may reflect a subgroup of greater general susceptibility to additional proarrhythmic effects.
T207 489-625 Sentence denotes In patients with arrhythmia in our cohort, QTc duration was longer at admission, albeit within normal range in the majority of patients.
T208 626-825 Sentence denotes Dynamic changes of the QTc interval under therapy with hydroxychloroquine and azithromycin cannot be evaluated as repeated ECGs during hospital stay were not systematically available in all patients.
T209 826-903 Sentence denotes Thus, proarrhythmic effects of these drugs cannot be excluded in this cohort.
T210 904-1091 Sentence denotes Previous reports point towards significant prolongation of the QTc interval by hydroxychloroquine in COVID-19 which is even more enhanced in combination with azithromycin therapy [25,26].
T211 1092-1177 Sentence denotes However, the rate of associated ventricular arrhythmia has been low in these studies.
T212 1178-1430 Sentence denotes Similarly, no typical “torsades des pointes” were seen in our cohort: in three of five patients with ventricular arrhythmias pre-existent cardiovascular disease was present, and only one of the remaining two patients received QTc-prolonging medication.
T213 1431-1594 Sentence denotes Thus, rather than induced by direct effects of administered medication, ventricular arrhythmias may have been due to other predisposing risk factors in our cohort.