Id |
Subject |
Object |
Predicate |
Lexical cue |
T89 |
0-4 |
Sentence |
denotes |
3.1. |
T90 |
5-60 |
Sentence |
denotes |
Baseline Characteristics and Outcomes in Overall Cohort |
T91 |
61-151 |
Sentence |
denotes |
Median age was 64.1 ± 16.7 years, and the majority of patients were male (n = 108, 65.1%). |
T92 |
152-230 |
Sentence |
denotes |
Arterial hypertension constituted the most common risk factor (n = 83, 50.0%). |
T93 |
231-384 |
Sentence |
denotes |
Cardiovascular disease was present in 18.1% (n = 30), cardiomyopathy in 3.0% (n = 5), diabetes mellitus in 17.5% (n = 29), and obesity in 21.7% (n = 36). |
T94 |
385-746 |
Sentence |
denotes |
Other relevant comorbidities comprised pulmonary disease (e.g., chronic obstructive pulmonary disease, pulmonary fibrosis) in 14.5% (n = 24), previous or active cancer disease in 8.4% (n = 14), and conditions associated with immunodeficiency (e.g., due to chronic immunosuppression therapy after organ transplantation or hematological disease) in 8.4% (n = 14). |
T95 |
747-841 |
Sentence |
denotes |
Information on left ventricular ejection fraction (LVEF) was available in 44 patients (26.5%). |
T96 |
842-886 |
Sentence |
denotes |
Mean LVEF in this subgroup was 53.0 ± 12.3%. |
T97 |
887-951 |
Sentence |
denotes |
In three patients a cardiac pacemaker had been implanted (1.8%). |
T98 |
952-1033 |
Sentence |
denotes |
Implanted cardioverter-defibrillators (ICDs) were present in two patients (1.2%). |
T99 |
1034-1136 |
Sentence |
denotes |
Seven patients (4.2%) presented with syncope in association with COVID-19 prior to hospital admission. |
T100 |
1137-1191 |
Sentence |
denotes |
Median duration of hospitalization was 10.5 days (P25: |
T101 |
1192-1204 |
Sentence |
denotes |
5 days; P75: |
T102 |
1205-1223 |
Sentence |
denotes |
22 days, n = 154). |
T103 |
1224-1368 |
Sentence |
denotes |
In 12 patients, data on duration of hospitalization could not be assessed due to transfer to a different center not participating in this study. |
T104 |
1369-1564 |
Sentence |
denotes |
The majority of patients required oxygen therapy in the course of hospital stay, and over a third of all patients was admitted to intensive care (ICU) or intermediate care units (IMC) (Figure 1). |
T105 |
1565-1616 |
Sentence |
denotes |
Median duration of ICU/IMC-therapy was 8 days (P25: |
T106 |
1617-1629 |
Sentence |
denotes |
4 days; P75: |
T107 |
1630-1641 |
Sentence |
denotes |
22.5 days). |
T108 |
1642-1881 |
Sentence |
denotes |
High-flow oxygen therapy and/or non-invasive ventilation (NIV) by continuous positive airway pressure (CPAP) was necessary in 39 patients (23.5%), and pharmacological circulatory support by vasopressors was provided in 30 patients (18.1%). |
T109 |
1882-1983 |
Sentence |
denotes |
Thirty-seven patients (22.3%) received mechanical ventilation with a median duration of 17 days (P25: |
T110 |
1984-1998 |
Sentence |
denotes |
7.5 days; P75: |
T111 |
1999-2008 |
Sentence |
denotes |
26 days). |
T112 |
2009-2101 |
Sentence |
denotes |
Of these, six patients had to be re-intubated after initially successful weaning (Figure 1). |
T113 |
2102-2239 |
Sentence |
denotes |
Only a minority of patients underwent extracorporeal membrane oxygenation (ECMO) or in-hospital cardiopulmonary resuscitation (Figure 1). |
T114 |
2240-2400 |
Sentence |
denotes |
With respect to cardiovascular events, myocarditis was suspected in one patient based on cardiac biomarker-kinetics and mildly reduced LVEF in echocardiography. |
T115 |
2401-2471 |
Sentence |
denotes |
This patient died due to respiratory failure during the hospital stay. |
T116 |
2472-2546 |
Sentence |
denotes |
However, the diagnosis of myocarditis could not be confirmed upon autopsy. |
T117 |
2547-2633 |
Sentence |
denotes |
Four patients were diagnosed with myocardial infarction (2.4%) during hospitalization. |
T118 |
2634-2867 |
Sentence |
denotes |
Percutaneous coronary intervention (PCI) was performed in two cases, of which one patient presented with ST segment elevation myocardial infarction (STEMI) and one patient with non-ST segment elevation myocardial infarction (NSTEMI). |
T119 |
2868-3062 |
Sentence |
denotes |
In the other two cases diagnosed with NSTEMI, medical therapy alone was preferred due to clinical instability with predominant respiratory symptoms and stable echocardiographic and ECG findings. |
T120 |
3063-3160 |
Sentence |
denotes |
One patient with NSTEMI and PCI died in the course of hospitalization due to mesenteric ischemia. |
T121 |
3161-3237 |
Sentence |
denotes |
Stroke or transient ischemic attack (TIA) was seen in three patients (1.8%). |
T122 |
3238-3388 |
Sentence |
denotes |
Twenty-six patients died during hospitalization, predominantly due to respiratory failure (n = 20, 76.9%) or other non-cardiac reasons (n = 5, 19.2%). |
T123 |
3389-3564 |
Sentence |
denotes |
Only one death was attributed to cardiac causes (3.8%), i.e., cardiac circulatory failure in a mechanically ventilated patient with pre-existent severe cardiovascular disease. |