PMC:7795888 / 18982-20163 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T117 0-252 Sentence denotes An important issue pertaining to emotion regulation concerns the interindividual variability in experiencing negative or positive affects, as well as the habitual tendency to prefer some regulatory strategies over others to control distressful affects.
T118 253-367 Sentence denotes On the one hand, depression has long been associated with increased levels of negative and stressful affects [35].
T119 368-552 Sentence denotes On the other hand, one of the key components of emotion dysregulation is the inability to regulate negative emotion and to decrease the duration of negative affect once it arises [36].
T120 553-721 Sentence denotes Consistently with this conceptual framework, there is evidence linking impaired emotion regulation mechanisms with depressive symptoms, also at a neurobiological level.
T121 722-920 Sentence denotes Indeed, depression has been repeatedly associated with dysfunction in brain regions that are normally implicated in emotion regulation, including prefrontal cortex, (PFC), amygdala, and hippocampus.
T122 921-1181 Sentence denotes Intriguingly, these regions have been implicated in the regulation of stress and coping, with the PFC and the hippocampus providing inhibitory control over stress responses, whereas the amygdala has been implicated in potentiating stress-related behaviors [5].