PMC:7787218 / 17403-20313 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T74 0-94 Sentence denotes Table 1 SARS-CoV-2 Vaccines under Emergency Use Authorization (EUA) or in Late-Phase Studies.
T75 95-224 Sentence denotes Vaccine Platform Type of Vaccine and Immunogen Developer(Name of Vaccine) Dose Scheduleand Administration Phase* Excipients†
T76 225-333 Sentence denotes RNA-based vaccine mRNA encoding spike protein (30 μg) BioNTech–Pfizer(BNT162b2) Two doses (day 0, day 21)
T77 334-730 Sentence denotes Intramuscular Post-EUA 0.43 mg ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-phosphocholine, and 0.2 mg cholesterol, 0.01 mg potassium chloride, 0.01 mg monobasic potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate, and 6 mg sucrose.
T78 731-834 Sentence denotes The diluent (0.9% sodium chloride Injection) contributes an additional 2.16 mg sodium chloride per dose
T79 835-937 Sentence denotes RNA-based vaccine mRNA encoding spike protein (100 μg) Moderna(mRNA-1273) Two doses (day 0, day 28)
T80 938-1208 Sentence denotes Intramuscular Post-EUA Lipids (SM-102; 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 [PEG 2000-DMG]; cholesterol; and 1,2-distearoyl-sn-glycero-3-phosphocholine [DSPC]), tromethamine, tromethamine hydrochloride, acetic acid, sodium acetate, and sucrose
T81 1209-1262 Sentence denotes Adenovirus vector (nonreplicating) ChAdOx1-Sn Cov-19
T82 1263-1407 Sentence denotes Nonreplicating chimpanzee AdV5 expressing spike protein AstraZeneca and University of Oxford(AZD1222) One (day 0) or two (day 0, day 28) doses
T83 1408-1594 Sentence denotes Intramuscular Phase 3 10 mM histidine, 7.5% (w/v) sucrose,35 mM sodium chloride, 1 mM magnesiumchloride, 0.1% (w/v) polysorbate 80,0.1 mM edetate disodium, 0.5% (w/v)ethanol, at pH 6.6
T84 1595-1641 Sentence denotes Adenovirus vector(nonreplicating) Ad26.COV2.S
T85 1642-1757 Sentence denotes Adenovirus 26 vectored vaccine using AdVac and PER.C6 technology Janssen One (day 0) or two (day 0, day 56) doses
T86 1758-1915 Sentence denotes Intramuscular Phase 3 Sodium chloride, citric acid monohydrate, polysorbate 80, 2 hydroxypropyl-B-cyclodextrin (HBCD), ethanol (absolute), sodium hydroxide
T87 1916-2016 Sentence denotes Protein subunit Full-length recombinant SARS-CoV-2 glycoprotein nanoparticle with Matrix M adjuvant
T88 2017-2076 Sentence denotes Spike prefusion protein Novavax Two doses (day 0, day 21)
T89 2077-2206 Sentence denotes Intramuscular Phase 3 Matrix M1 adjuvantFull-length spike protein formulated in polysorbate 80 detergent and Matrix M1 adjuvant
T90 2207-2305 Sentence denotes Protein subunit SARS-CoV-2 vaccine formulation with adjuvant (S-protein) (Baculovirus production)
T91 2306-2370 Sentence denotes Spike protein Sanofi Pasteur and GSK Two doses (day 0, day 21)
T92 2371-2574 Sentence denotes Intramuscular Phase 1–2 Sodium phosphate monobasic monohydrate, sodium phosphate dibasic, sodium chloride polysorbate 20, disodium hydrogen phosphate, potassium dihydrogen phosphate, potassium chloride
T93 2575-2632 Sentence denotes * Phase information was current as of December 21, 2020.
T94 2633-2677 Sentence denotes In all cases, the placebo was normal saline.
T95 2678-2832 Sentence denotes † Bold entries are excipients potentially related to vaccine reaction that may be cross-reactive to other excipients (e.g., PEG 2000 and polysorbate 80).
T96 2833-2910 Sentence denotes SM-102, a component of the Moderna vaccine, is a proprietary ionizable lipid.