LitCovid-sentences  

PMC:7787218 / 15197-17402 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T62 0-42 Sentence denotes Figure 1 Assessing Reactions to Vaccines.
T63 43-236 Sentence denotes SARS-CoV-2 mRNA vaccines are built on the same lipid-based nanoparticle carrier technology; however, the lipid component of the Pfizer-BioNTech vaccine differs from that of the Moderna vaccine.
T64 237-530 Sentence denotes Operation Warp Speed has led to an unprecedented response to the study of the safety and effectiveness of new vaccine platforms never before used in humans and to the development of vaccines that have been authorized for use less than a year after the SARS-CoV-2 viral sequence was discovered.
T65 531-760 Sentence denotes The next few months could see the authorization of several such vaccines, and inevitably, adverse drug events will be recognized in the coming months that were not seen in the studies conducted before emergency use authorization.
T66 761-880 Sentence denotes Maintenance of vaccine safety requires a proactive approach to maintain public confidence and reduce vaccine hesitancy.
T67 881-1132 Sentence denotes This approach involves not only vigilance but also meticulous response, documentation, and characterization of these events to heighten recognition and allow definition of mechanisms and appropriate approaches to prediction, prevention, and treatment.
T68 1133-1314 Sentence denotes A systematic approach to an adverse reaction to any vaccine requires clinical recognition and appropriate initial treatment, followed by a detailed history and causality assessment.
T69 1315-1582 Sentence denotes Nonimmune immediate reactions such as vasovagal reactions are common and typically manifest with diaphoresis, nausea, vomiting, pallor, and bradycardia, in contrast to the flush, pruritus, urticaria, angioedema, tachycardia, and laryngeal edema seen with anaphylaxis.
T70 1583-1729 Sentence denotes Post-reaction clinical assessment by an allergist–immunologist that includes skin testing for allergy to components of the vaccine can be helpful.
T71 1730-1947 Sentence denotes Use of other laboratory information may aid in clinical and mechanistic assessment and guide future vaccine and drug safety as well as management, such as rechallenge with alternative vaccines if redosing is required.
T72 1948-2059 Sentence denotes A useful resource for searching the excipients of drugs and vaccines is https://dailymed.nlm.nih.gov/dailymed/.
T73 2060-2205 Sentence denotes A useful resource for excipients in licensed vaccines is https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf.