PMC:7784829 / 26414-27158 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T292 0-96 Sentence denotes The spike proteins of corona viruses are essential for entry of the virus into the target cells.
T293 97-265 Sentence denotes The spike protein exists as a trimer on the surface of the virus with one of the monomer in up conformation and the other two in down conformation (Wrapp et al., 2020).
T294 266-407 Sentence denotes The N-terminal region (S1) of the S protein is important for binding to the cellular receptor ACE2 (Hoffmann et al., 2020; Tai et al., 2020).
T295 408-584 Sentence denotes The S protein undergoes priming by cellular protease, TMPRSS2 and the S2 region of the protein is responsible for fusion of viral and cellular membrane (Hoffmann et al., 2020).
T296 585-744 Sentence denotes Therefore, identifying therapeutics for the S protein of the novel corona virus could potentially target the critical process of entry and fusion of the virus.