PMC:7784786 / 14097-14694 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T127 0-111 Sentence denotes Several anticytokine therapies have been tried for treating the hyperinflammatory phase of COVID-19 [20,23–25].
T128 112-239 Sentence denotes Here, we report the use of a well-known anti-inflammatory antibody targeting CD6 to treat the CRS arising in COVID-19 patients.
T129 240-471 Sentence denotes Using an anti-CD6 antibody could reduce the concentration of several pro-inflammatory cytokines, including IL-6, IFN-γ, TNF-α and IL-17, among others, representing an advantage as compared with single-cytokine targeting antibodies.
T130 472-597 Sentence denotes The antibody would not exacerbate lymphopenia since it does not induce complement or antibody dependent cytotoxicity [10,11].