PMC:7784786 / 10222-11788 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T92 0-10 Sentence denotes Patient 3:
T93 11-119 Sentence denotes An 81-year old female, who is COVID-19 positive contact was not identified at the moment of hospitalization.
T94 120-278 Sentence denotes She started symptoms on 2 April and entered the ICU on 5 April. Patient has a previous history of hypertension, diabetes mellitus, glaucoma and smoking habit.
T95 279-339 Sentence denotes She was admitted with frequent cough, wheezing and diarrhea.
T96 340-420 Sentence denotes The diagnosis of viral pneumonia by COVID-19 was confirmed by RT-PCR on 7 April.
T97 421-539 Sentence denotes Oxygen support at 5 l/min and treatment with ceftriaxone, lopinavir–ritonavir, chloroquine and IFN α-2b was indicated.
T98 540-610 Sentence denotes Chest images showed bilateral interstitial infiltration in both lungs.
T99 611-716 Sentence denotes Patient condition was classified as severe, although she did not require invasive mechanical ventilation.
T100 717-798 Sentence denotes A dose of itolizumab (200 mg) was given the day after her admission into the ICU.
T101 799-1045 Sentence denotes Two days after the antibody administration, together with the rest of the therapy, there was an improvement of the respiratory distress while the chest image showed a decrease of the alveolar interstitial infiltrate of both lungs (Figure 1C & D).
T102 1046-1121 Sentence denotes Patient left the ICU after a favorable clinical and radiological evolution.
T103 1122-1198 Sentence denotes IL-6 concentration was measured prior and after the antibody administration.
T104 1199-1374 Sentence denotes IL-6 level at baseline was lower than in previous cases (30 pg/ml), but also decreased 48 h and 168 h after itolizumab infusion, in parallel with patient recovery (Figure 2A).
T105 1375-1457 Sentence denotes IL-1 and TNF-α were untraceable before and 48 h after the antibody administration.
T106 1458-1566 Sentence denotes Regarding to AST concentration, the values were in the normal range during the treatment period (Figure 2B).