PMC:7781431 / 8727-9584 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T70 0-39 Sentence denotes RvD is a polyhydroxy metabolite of DHA.
T71 40-197 Sentence denotes To date, six RvDs with different positions of cis-trans isomers, as well as the number, position and chirality of the hydroxyl residues have been discovered.
T72 198-299 Sentence denotes D-series Rvs (RvD1-RvD6) are biosynthesized from DHA by the LOX in PMN and macrophages (Serhan et al.
T73 300-306 Sentence denotes 2002).
T74 307-396 Sentence denotes Hydrolysis of peroxide intermediates derived from two LOXs in DHA produces RvD1 and RvD2.
T75 397-488 Sentence denotes On the other hand, the reduction of the peroxide intermediates produces RvD5 (Serhan et al.
T76 489-495 Sentence denotes 2002).
T77 496-696 Sentence denotes In hypoxic endothelial cells in the presence of aspirin, COX-2 converts DHA to 13-hydroxy-DHA or 17R-hydroxy-DHA and activated PMN converts these products to AT-RvD1, AT-RvD2, and other AT-RvD-series.
T78 697-857 Sentence denotes RvD3 and RvD4 are produced through hydrolysis of 4S-hydroperoxy-17S-hydroxy-docosahexaenoic acid, whereas RvD6 is derived from peroxidase of the same precursor.